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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132523
log Bayes Factor = 56.8571
Chromosome 6   position 31,136,832  (GRCh37) Explore rs3132523 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E78.0 Pure hypercholesterolaemia
0.000 0.011 0.989
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.014 0.986
E70-E90 Metabolic disorders
0.000 0.018 0.981
G35 Multiple sclerosis
0.975 0.025 0.000
L40 Psoriasis
0.000 0.037 0.963
E14 Unspecified diabetes mellitus
0.000 0.045 0.955
L40.5 Arthropathic psoriasis
0.000 0.085 0.915
E11.0 With coma
0.000 0.136 0.864
E14.3 With ophthalmic complications
0.000 0.141 0.859
E10.3 With ophthalmic complications
0.000 0.143 0.857
E78.8 Other disorders of lipoprotein metabolism
0.000 0.143 0.857
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.162 0.838
E14.9 Without complications
0.000 0.166 0.834
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.166 0.834
E07 Other disorders of thyroid
0.000 0.175 0.825
E78.2 Mixed hyperlipidaemia
0.000 0.176 0.824
L40.0 Psoriasis vulgaris
0.000 0.180 0.820
L40.8 Other psoriasis
0.000 0.192 0.808
E03.8 Other specified hypothyroidism
0.000 0.193 0.807
E11.1 With ketoacidosis
0.000 0.204 0.795
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.215 0.785
E79 Disorders of purine and pyrimidine metabolism
0.000 0.232 0.768
E74 Other disorders of carbohydrate metabolism
0.000 0.234 0.766
E10.6 With other specified complications
0.000 0.244 0.755
E14.5 With peripheral circulatory complications
0.000 0.246 0.754
E10.8 With unspecified complications
0.000 0.248 0.752
E78.1 Pure hyperglyceridaemia
0.000 0.252 0.748
E13 Other specified diabetes mellitus
0.000 0.259 0.741
L40.1 Generalised pustular psoriasis
0.000 0.264 0.736
K90 Intestinal malabsorption
0.000 0.274 0.726
E10.1 With ketoacidosis
0.000 0.282 0.718
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E11.2 With renal complications
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
E14.4 With neurological complications
0.000 0.287 0.713
E78.4 Other hyperlipidaemia
0.000 0.288 0.712
E07.9 Disorder of thyroid, unspecified
0.000 0.288 0.712
E10.0 With coma
0.000 0.289 0.711
E40-E46 Malnutrition
0.000 0.290 0.709
G35-G37 Demyelinating diseases of the central nervous system
0.709 0.290 0.000
E78.6 Lipoprotein deficiency
0.000 0.291 0.709
E78.3 Hyperchylomicronaemia
0.000 0.293 0.707
E77 Disorders of glycoprotein metabolism
0.000 0.296 0.704
E76 Disorders of glycosaminoglycan metabolism
0.000 0.296 0.704
E72 Other disorders of amino-acid metabolism
0.000 0.296 0.704
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.296 0.704
E70 Disorders of aromatic amino-acid metabolism
0.000 0.296 0.704
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.296 0.704
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.309 0.691
L40.2 Acrodermatitis continua
0.000 0.309 0.690
E14.6 With other specified complications
0.000 0.310 0.690
E14.1 With ketoacidosis
0.000 0.312 0.688
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.312 0.688
L40.4 Guttate psoriasis
0.000 0.315 0.685
E14.7 With multiple complications
0.000 0.315 0.685
E14.0 With coma
0.000 0.315 0.685
E84 Cystic fibrosis
0.000 0.322 0.678
E14.2 Withrenal complications
0.000 0.322 0.678
E80.4 Gilbert's syndrome
0.000 0.331 0.669
E80.6 Other disorders of bilirubin metabolism
0.000 0.343 0.657
E78.5 Hyperlipidaemia, unspecified
0.000 0.345 0.655
E83 Disorders of mineral metabolism
0.617 0.345 0.038
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.352 0.648
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.355 0.645
E14.8 With unspecified complications
0.000 0.356 0.644
G37 Other demyelinating diseases of central nervous system
0.643 0.357 0.000
E80.2 Other porphyria
0.000 0.363 0.637
E03.1 Congenital hypothyroidism without goitre
0.000 0.366 0.634
E16 Other disorders of pancreatic internal secretion
0.000 0.368 0.632
E11.8 With unspecified complications
0.000 0.372 0.628
E10.2 With renal complications
0.000 0.381 0.619
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.384 0.615
E10.5 With peripheral circulatory complications
0.000 0.389 0.611
C83.3 Large cell (diffuse)
0.000 0.398 0.602
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.402 0.598
E80.5 Crigler-Najjar syndrome
0.000 0.402 0.598
E80.3 Defects of catalase and peroxydase
0.000 0.402 0.598
E80.0 Hereditary erythropoietic porphyria
0.000 0.402 0.598
E80.1 Porphyria cutanea tarda
0.000 0.407 0.593
E05.8 Other thyrotoxicosis
0.000 0.407 0.593
E07.1 Dyshormogenetic goitre
0.000 0.408 0.591
E07.0 Hypersecretion of calcitonin
0.000 0.408 0.591
E88 Other metabolic disorders
0.000 0.410 0.590
G37.9 Demyelinating disease of central nervous system, unspecified
0.582 0.418 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.419 0.581
E13.9 Without complications
0.000 0.424 0.576
E73 Lactose intolerance
0.000 0.430 0.570
L40.3 Pustulosis palmaris et plantaris
0.000 0.433 0.566
E07.8 Other specified disorders of thyroid
0.000 0.434 0.566
L40-L45 Papulosquamous disorders
0.000 0.435 0.565
E15 Nondiabetic hypoglycaemic coma
0.000 0.437 0.563
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.449 0.551
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.449 0.551
E79.1 Lesch-Nyhan syndrome
0.000 0.449 0.551
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.451 0.549
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.451 0.549
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.451 0.549
E74.2 Disorders of galactose metabolism
0.000 0.451 0.549
E74.1 Disorders of fructose metabolism
0.000 0.451 0.549
G36 Other acute disseminated demyelination
0.544 0.456 0.000
E83.3 Disorders of phosphorus metabolism
0.524 0.465 0.011
E13.8 With unspecified complications
0.000 0.469 0.531
E13.7 With multiple complications
0.000 0.469 0.531
E13.6 With other specified complications
0.000 0.469 0.531
E13.5 With peripheral circulatory complications
0.000 0.469 0.531
E13.4 With neurological complications
0.000 0.469 0.531
E13.2 With renal complications
0.000 0.469 0.531
E13.1 With ketoacidosis
0.000 0.469 0.531
E13.0 With coma
0.000 0.469 0.531
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.470 0.530
K90.3 Pancreatic steatorrhoea
0.000 0.479 0.520
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.479 0.520
K90.1 Tropical sprue
0.000 0.479 0.520
G37.8 Other specified demyelinating diseases of central nervous system
0.518 0.482 0.000
E10.4 With neurological complications
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.491 0.509
E45 Retarded development following protein-energy malnutrition
0.000 0.491 0.509
E43 Unspecified severe protein-energy malnutrition
0.000 0.491 0.509
E42 Marasmic kwashiorkor
0.000 0.491 0.509
E41 Nutritional marasmus
0.000 0.491 0.509
E40 Kwashiorkor
0.000 0.491 0.509
E11.5 With peripheral circulatory complications
0.000 0.491 0.509
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.495 0.504
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.495 0.504
E70.3 Albinism
0.000 0.495 0.504
E70.2 Disorders of tyrosine metabolism
0.000 0.495 0.504
E70.1 Other hyperphenylalaninaemias
0.000 0.495 0.504
E70.0 Classical phenylketonuria
0.000 0.495 0.504
E71.3 Disorders of fatty-acid metabolism
0.000 0.495 0.504
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.495 0.504
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.495 0.504
E71.0 Maple-syrup-urine disease
0.000 0.495 0.504
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.495 0.504
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.495 0.504
E72.5 Disorders of glycine metabolism
0.000 0.495 0.504
E72.4 Disorders of ornithine metabolism
0.000 0.495 0.504
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.495 0.504
E72.2 Disorders of urea cycle metabolism
0.000 0.495 0.504
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.495 0.504
E72.0 Disorders of amino-acid transport
0.000 0.495 0.504
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.495 0.504
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.495 0.504
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.495 0.504
E76.2 Other mucopolysaccharidoses
0.000 0.495 0.504
E76.1 Mucopolysaccharidosis, type II
0.000 0.495 0.504
E76.0 Mucopolysaccharidosis, type I
0.000 0.495 0.504
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.495 0.504
E77.8 Other disorders of glycoprotein metabolism
0.000 0.495 0.504
E77.1 Defects in glycoprotein degradation
0.000 0.495 0.504
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.495 0.504
E13.3 With ophthalmic complications
0.000 0.495 0.504
E83.9 Disorder of mineral metabolism, unspecified
0.478 0.498 0.024
E46 Unspecified protein-energy malnutrition
0.000 0.498 0.501
K90.8 Other intestinal malabsorption
0.000 0.500 0.500
E16.2 Hypoglycaemia, unspecified
0.000 0.501 0.499
E16.1 Other hypoglycaemia
0.000 0.506 0.494
E75.6 Lipid storage disorder, unspecified
0.000 0.507 0.493
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.507 0.493
E75.3 Sphingolipidosis, unspecified
0.000 0.507 0.493
E75.2 Other sphingolipidosis
0.000 0.507 0.493
E75.1 Other gangliosidosis
0.000 0.507 0.493
E75.0 GM2 gangliosidosis
0.000 0.507 0.493
E74.0 Glycogen storage disease
0.000 0.512 0.488
E84.8 Cystic fibrosis with other manifestations
0.000 0.514 0.486
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.514 0.486
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.514 0.486
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.001 0.521 0.479
C83 Diffuse non-Hodgkin's lymphoma
0.003 0.521 0.476
E75.5 Other lipid storage disorders
0.000 0.522 0.477
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.528 0.472
C85.1 B-cell lymphoma, unspecified
0.000 0.529 0.471
E11.6 With other specified complications
0.000 0.530 0.469
E83.8 Other disorders of mineral metabolism
0.442 0.531 0.027
E83.2 Disorders of zinc metabolism
0.442 0.531 0.027
E83.0 Disorders of copper metabolism
0.442 0.531 0.027
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.005 0.533 0.463
E88.2 Lipomatosis, not elsewhere classified
0.000 0.538 0.462
G37.5 Concentric sclerosis [Balo]
0.461 0.539 0.000
G37.4 Subacute necrotising myelitis
0.461 0.539 0.000
G37.2 Central pontine myelinolysis
0.461 0.539 0.000
G37.1 Central demyelination of corpus callosum
0.461 0.539 0.000
G37.0 Diffuse sclerosis
0.461 0.539 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.539 0.460
L43 Lichen planus
0.000 0.540 0.460
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.001 0.545 0.454
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.547 0.453
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.547 0.453
E16.4 Abnormal secretion of gastrin
0.000 0.547 0.453
E16.3 Increased secretion of glucagon
0.000 0.547 0.453
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.550 0.449
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.557 0.443
L42 Pityriasis rosea
0.000 0.559 0.441
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.560 0.440
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.439 0.560 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.560 0.440
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.563 0.436
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.565 0.435
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.567 0.433
G36.0 Neuromyelitis optica [Devic]
0.426 0.574 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.577 0.423
E88.8 Other specified metabolic disorders
0.000 0.577 0.423
E88.3 Tumour lysis syndrome
0.000 0.582 0.418
E11.4 With neurological complications
0.000 0.582 0.418
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.588 0.412
L43.9 Lichen planus, unspecified
0.000 0.590 0.410
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.590 0.409
E73.8 Other lactose intolerance
0.000 0.591 0.408
E73.1 Secondary lactase deficiency
0.000 0.591 0.408
E73.0 Congenital lactase deficiency
0.000 0.591 0.408
L44 Other papulosquamous disorders
0.000 0.595 0.405
L41 Parapsoriasis
0.000 0.595 0.405
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.595 0.405
E89.4 Postprocedural ovarian failure
0.000 0.596 0.404
E85 Amyloidosis
0.001 0.606 0.393
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.608 0.392
G36.9 Acute disseminated demyelination, unspecified
0.390 0.610 0.000
G36.8 Other specified acute disseminated demyelination
0.390 0.610 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.390 0.610 0.000
E06 Thyroiditis
0.000 0.612 0.387
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.614 0.386
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.620 0.380
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.620 0.380
E89.5 Postprocedural testicular hypofunction
0.000 0.620 0.380
E89.1 Postprocedural hypoinsulinaemia
0.000 0.620 0.380
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.628 0.372
C83.7 Burkitt's tumour
0.002 0.630 0.368
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.632 0.368
C82.2 Large cell, follicular
0.001 0.632 0.367
E89.3 Postprocedural hypopituitarism
0.000 0.634 0.366
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.634 0.366
E44.1 Mild protein-energy malnutrition
0.000 0.635 0.365
E44.0 Moderate protein-energy malnutrition
0.000 0.635 0.365
C82.3 Follicular lymphoma grade IIIa
0.001 0.647 0.352
C81 Hodgkin's disease
0.002 0.653 0.344
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.654 0.346
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.001 0.656 0.343
C85.0 Lymphosarcoma
0.001 0.656 0.343
C83.6 Undifferentiated (diffuse)
0.002 0.656 0.341
C83.5 Lymphoblastic (diffuse)
0.002 0.656 0.341
C83.4 Immunoblastic (diffuse)
0.002 0.656 0.341
C83.2 Mixed small and large cell (diffuse)
0.002 0.656 0.341
E83.4 Disorders of magnesium metabolism
0.324 0.662 0.014
E20-E35 Disorders of other endocrine glands
0.000 0.663 0.337
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.003 0.665 0.332
C86 Other specified types of T/NK-cell lymphoma
0.003 0.665 0.332
C84 Peripheral and cutaneous T-cell lymphomas
0.003 0.665 0.332
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.666 0.334
E65-E68 Obesity and other hyperalimentation
0.000 0.670 0.330
L43.3 Subacute (active) lichen planus
0.000 0.670 0.330
L43.2 Lichenoid drug reaction
0.000 0.670 0.330
L43.1 Bullous lichen planus
0.000 0.670 0.330
L43.0 Hypertrophic lichen planus
0.000 0.670 0.330
C82.6 Cutaneous follicle centre lymphoma
0.001 0.674 0.325
C82.5 Diffuse follicle centre lymphoma
0.001 0.674 0.325
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.001 0.674 0.325
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.675 0.325
E89.2 Postprocedural hypoparathyroidism
0.000 0.677 0.323
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.002 0.681 0.316
C82.0 Small cleaved cell, follicular
0.001 0.688 0.311
C94 Other leukaemias of specified cell type
0.004 0.693 0.303
C82.4 Follicular lymphoma grade IIIb
0.001 0.697 0.302
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.699 0.301
C81.9 Hodgkin's disease, unspecified
0.001 0.702 0.297
E28 Ovarian dysfunction
0.000 0.704 0.296
L41.9 Parapsoriasis, unspecified
0.000 0.709 0.290
L41.8 Other parapsoriasis
0.000 0.709 0.290
L41.5 Retiform parapsoriasis
0.000 0.709 0.290
L41.4 Large plaque parapsoriasis
0.000 0.709 0.290
L41.3 Small plaque parapsoriasis
0.000 0.709 0.290
L41.2 Lymphomatoid papulosis
0.000 0.709 0.290
L41.1 Pityriasis lichenoides chronica
0.000 0.709 0.290
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.709 0.290
L44.9 Papulosquamous disorder, unspecified
0.000 0.709 0.290
L44.8 Other specified papulosquamous disorders
0.000 0.709 0.290
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.709 0.290
L44.3 Lichen ruber moniliformis
0.000 0.709 0.290
L44.2 Lichen striatus
0.000 0.709 0.290
L44.1 Lichen nitidus
0.000 0.709 0.290
L44.0 Pityriasis rubra pilaris
0.000 0.709 0.290
C93 Monocytic leukaemia
0.004 0.714 0.282
E83.5 Disorders of calcium metabolism
0.279 0.717 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.717 0.282
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.717 0.282
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.717 0.282
E06.5 Other chronic thyroiditis
0.000 0.722 0.278
E06.4 Drug-induced thyroiditis
0.000 0.722 0.278
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.722 0.278
E06.0 Acute thyroiditis
0.000 0.722 0.278
E28.2 Polycystic ovarian syndrome
0.000 0.723 0.277
C83.1 Small cleaved cell (diffuse)
0.003 0.724 0.273
E23 Hypofunction and other disorders of pituitary gland
0.000 0.725 0.275
E73.9 Lactose intolerance, unspecified
0.001 0.725 0.274
E24 Cushing's syndrome
0.000 0.728 0.272
E85.8 Other amyloidosis
0.001 0.731 0.268
C91 Lymphoid leukaemia
0.003 0.734 0.263
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.735 0.265
E06.1 Subacute thyroiditis
0.000 0.735 0.264
C88 Malignant immunoproliferative diseases
0.004 0.736 0.260
L43.8 Other lichen planus
0.000 0.736 0.264
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.740 0.260
E50-E64 Other nutritional deficiencies
0.000 0.740 0.260
E85.9 Amyloidosis, unspecified
0.001 0.746 0.253
C84.5 Other and unspecified T-cell lymphomas
0.002 0.750 0.248
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.002 0.751 0.247
C81.3 Lymphocytic depletion
0.002 0.751 0.247
C81.2 Mixed cellularity
0.002 0.751 0.247
C81.7 Other Hodgkin's disease
0.002 0.753 0.245
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.758 0.241
E32 Diseases of thymus
0.000 0.758 0.241
E31 Polyglandular dysfunction
0.000 0.758 0.241
E30 Disorders of puberty, not elsewhere classified
0.000 0.758 0.241
E25 Adrenogenital disorders
0.000 0.758 0.241
C84.0 Mycosis fungoides
0.002 0.759 0.239
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.003 0.759 0.238
C86.5 Angioimmunoblastic T-cell lymphoma
0.003 0.759 0.238
C86.4 Blastic NK-cell lymphoma
0.003 0.759 0.238
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.003 0.759 0.238
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.003 0.759 0.238
C86.1 Hepatosplenic T-cell lymphoma
0.003 0.759 0.238
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.003 0.759 0.238
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.003 0.759 0.238
C96.8 Histiocytic sarcoma
0.003 0.759 0.238
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.003 0.759 0.238
C96.6 Unifocal Langerhans-cell histiocytosis
0.003 0.759 0.238
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.003 0.759 0.238
C96.4 Sarcoma of dendritic cells (accessory cells)
0.003 0.759 0.238
C96.3 True histiocytic lymphoma
0.003 0.759 0.238
C96.2 Malignant mast cell tumour
0.003 0.759 0.238
C96.1 Malignant histiocytosis
0.003 0.759 0.238
C96.0 Letterer-Siwe disease
0.003 0.759 0.238
C84.9 Mature T/NK-cell lymphoma, unspecified
0.002 0.760 0.238
C84.8 Cutaneous T-cell lymphoma, unspecified
0.002 0.760 0.238
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.002 0.760 0.238
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.002 0.760 0.238
C84.3 Lymphoepithelioid lymphoma
0.002 0.760 0.238
C84.2 T-zone lymphoma
0.002 0.760 0.238
C84.1 Sezary's diease
0.002 0.760 0.238
C81.0 Lymphocytic predominance
0.002 0.760 0.238
E21.3 Hyperparathyroidism, unspecified
0.000 0.762 0.238
C91.9 Lymphoid leukaemia, unspecified
0.001 0.763 0.236
E67 Other hyperalimentation
0.000 0.763 0.237
E68 Sequelae of hyperalimentation
0.000 0.763 0.237
C82.1 Mixed small cleaved and large cell, follicular
0.001 0.765 0.234
C84.4 Peripheral T-cell lymphoma
0.002 0.772 0.226
E23.7 Disorder of pituitary gland, unspecified
0.000 0.776 0.224
E85.4 Organ-limited amyloidosis
0.001 0.777 0.222
C95 Leukaemia of unspecified cell type
0.004 0.777 0.218
C94.7 Other specified leukaemias
0.003 0.780 0.218
C94.5 Acute myelofibrosis
0.003 0.780 0.218
C94.4 Acute panmyelosis
0.003 0.780 0.218
C94.3 Mast cell leukaemia
0.003 0.780 0.218
C94.2 Acute megakaryoblastic leukaemia
0.003 0.780 0.218
C94.1 Chronic erythraemia
0.003 0.780 0.218
C94.0 Acute erythraemia and erythroleukaemia
0.003 0.780 0.218
E11.3 With ophthalmic complications
0.000 0.780 0.220
E23.2 Diabetes insipidus
0.000 0.782 0.218
E24.2 Drug-induced Cushing's syndrome
0.000 0.782 0.217
K91.4 Colostomy and enterostomy malfunction
0.216 0.784 0.000
E26 Hyperaldosteronism
0.000 0.785 0.215
E28.9 Ovarian dysfunction, unspecified
0.000 0.788 0.212
E28.8 Other ovarian dysfunction
0.000 0.788 0.212
E28.1 Androgen excess
0.000 0.788 0.212
E28.0 Oestrogen excess
0.000 0.788 0.212
E24.9 Cushing's syndrome, unspecified
0.000 0.794 0.206
C93.9 Monocytic leukaemia, unspecified
0.003 0.795 0.202
C93.7 Other monocytic leukaemia
0.003 0.795 0.202
C93.3 Juvenile myelomonocytic leukaemia
0.003 0.795 0.202
C93.2 Subacute monocytic leukaemia
0.003 0.795 0.202
C93.0 Acute monocytic leukaemia
0.003 0.795 0.202
M06 Other rheumatoid arthritis
0.000 0.797 0.203
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.798 0.202
E85.3 Secondary systemic amyloidosis
0.001 0.800 0.199
E20 Hypoparathyroidism
0.000 0.802 0.198
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.803 0.197
E23.1 Drug-induced hypopituitarism
0.000 0.803 0.197
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.805 0.195
E24.8 Other Cushing's syndrome
0.000 0.805 0.195
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.805 0.195
E24.3 Ectopic ACTH syndrome
0.000 0.805 0.195
E24.1 Nelson's syndrome
0.000 0.805 0.195
E24.0 Pituitary-dependent Cushing's disease
0.000 0.805 0.195
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.003 0.807 0.190
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.807 0.193
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.003 0.808 0.189
C91.5 Adult T-cell leukaemia
0.002 0.808 0.190
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.003 0.808 0.189
E23.6 Other disorders of pituitary gland
0.000 0.808 0.191
C81.1 Nodular sclerosis
0.002 0.809 0.189
C91.8 Mature B-cell leukaemia Burkitt-type
0.002 0.809 0.188
C91.7 Other lymphoid leukaemia
0.002 0.809 0.188
C91.6 Prolymphocytic leukaemia of T-cell type
0.002 0.809 0.188
C91.3 Prolymphocytic leukaemia
0.002 0.809 0.188
C91.2 Subacute lymphocytic leukaemia
0.002 0.809 0.188
C83.0 Small cell (diffuse)
0.003 0.810 0.187
E21.4 Other specified disorders of parathyroid gland
0.000 0.810 0.190
E21.2 Other hyperparathyroidism
0.000 0.810 0.190
E23.0 Hypopituitarism
0.000 0.810 0.190
C88.9 Malignant immunoproliferative disease, unspecified
0.003 0.811 0.186
C88.7 Other malignant immunoproliferative diseases
0.003 0.811 0.186
C88.3 Immunoproliferative small intestinal disease
0.003 0.811 0.186
C88.2 Gamma heavy chain disease
0.003 0.811 0.186
C88.1 Alpha heavy chain disease
0.003 0.811 0.186
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.813 0.186
E63 Other nutritional deficiencies
0.000 0.813 0.186
E50 Vitamin A deficiency
0.000 0.813 0.186
E60 Dietary zinc deficiency
0.000 0.813 0.186
E59 Dietary selenium deficiency
0.000 0.813 0.186
E54 Ascorbic acid deficiency
0.000 0.813 0.186
E52 Niacin deficiency [pellagra]
0.000 0.813 0.186
E29 Testicular dysfunction
0.000 0.817 0.183
E56 Other vitamin deficiencies
0.000 0.817 0.182
E06.3 Autoimmune thyroiditis
0.000 0.819 0.180
E58 Dietary calcium deficiency
0.000 0.819 0.180
E06.9 Thyroiditis, unspecified
0.001 0.820 0.180
C92 Myeloid leukaemia
0.004 0.824 0.172
M06.3 Rheumatoid nodule
0.000 0.825 0.175
E51 Thiamine deficiency
0.000 0.825 0.174
E65 Localised adiposity
0.000 0.826 0.174
E25.9 Adrenogenital disorder, unspecified
0.000 0.827 0.173
E25.8 Other adrenogenital disorders
0.000 0.827 0.173
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.827 0.173
E30.9 Disorder of puberty, unspecified
0.000 0.827 0.173
E30.8 Other disorders of puberty
0.000 0.827 0.173
E30.1 Precocious puberty
0.000 0.827 0.173
E30.0 Delayed puberty
0.000 0.827 0.173
E31.9 Polyglandular dysfunction, unspecified
0.000 0.827 0.173
E31.8 Other polyglandular dysfunction
0.000 0.827 0.173
E31.1 Polyglandular hyperfunction
0.000 0.827 0.173
E31.0 Autoimmune polyglandular failure
0.000 0.827 0.173
E32.9 Disease of thymus, unspecified
0.000 0.827 0.173
E32.8 Other diseases of thymus
0.000 0.827 0.173
E32.1 Abscess of thymus
0.000 0.827 0.173
E32.0 Persistent hyperplasia of thymus
0.000 0.827 0.173
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.827 0.173
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.827 0.173
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.827 0.173
C91.0 Acute lymphoblastic leukaemia
0.002 0.830 0.168
E67.8 Other specified hyperalimentation
0.000 0.830 0.170
E67.3 Hypervitaminosis D
0.000 0.830 0.170
E67.2 Megavitamin-B6 syndrome
0.000 0.830 0.170
E67.1 Hypercarotenaemia
0.000 0.830 0.170
E67.0 Hypervitaminosis A
0.000 0.830 0.170
E28.3 Primary ovarian failure
0.000 0.835 0.165
E61 Deficiency of other nutrient elements
0.000 0.837 0.163
C95.7 Other leukaemia of unspecified cell type
0.003 0.840 0.157
C95.2 Subacute leukaemia of unspecified cell type
0.003 0.840 0.157
C93.1 Chronic monocytic leukaemia
0.004 0.845 0.152
E26.9 Hyperaldosteronism, unspecified
0.000 0.846 0.154
E26.8 Other hyperaldosteronism
0.000 0.846 0.154
E26.1 Secondary hyperaldosteronism
0.000 0.846 0.154
E22 Hyperfunction of pituitary gland
0.000 0.846 0.154
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.852 0.148
M06.34 Rheumatoid nodule (Hand)
0.000 0.853 0.147
M06.4 Inflammatory polyarthropathy
0.000 0.854 0.146
M06.2 Rheumatoid bursitis
0.000 0.854 0.146
M06.1 Adult-onset Still's disease
0.000 0.854 0.146
C90 Multiple myeloma and malignant plasma cell neoplasms
0.062 0.857 0.081

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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