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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132538
log Bayes Factor = 46.7526
Chromosome 6   position 31,113,842  (GRCh37) Explore rs3132538 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
E10 Insulin-dependent diabetes mellitus
0.000 0.005 0.995
E11.9 Without complications
0.000 0.005 0.995
E10.9 Without complications
0.000 0.006 0.994
E11 Non-insulin-dependent diabetes mellitus
0.000 0.007 0.993
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
L40 Psoriasis
0.000 0.016 0.984
E70-E90 Metabolic disorders
0.000 0.018 0.981
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.027 0.973
E05.9 Thyrotoxicosis, unspecified
0.000 0.029 0.971
L40.5 Arthropathic psoriasis
0.000 0.044 0.956
E14 Unspecified diabetes mellitus
0.000 0.096 0.904
L40.8 Other psoriasis
0.000 0.126 0.874
G35-G37 Demyelinating diseases of the central nervous system
0.873 0.127 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.129 0.871
G37 Other demyelinating diseases of central nervous system
0.839 0.161 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.171 0.829
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.176 0.824
E14.3 With ophthalmic complications
0.000 0.182 0.818
M06.9 Rheumatoid arthritis, unspecified
0.000 0.184 0.816
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.187 0.813
G37.9 Demyelinating disease of central nervous system, unspecified
0.801 0.199 0.000
E11.0 With coma
0.000 0.201 0.799
L40.0 Psoriasis vulgaris
0.000 0.201 0.799
E10.8 With unspecified complications
0.000 0.217 0.783
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.217 0.783
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.224 0.776
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.235 0.765
E13 Other specified diabetes mellitus
0.000 0.239 0.761
E10.3 With ophthalmic complications
0.000 0.240 0.760
E78.1 Pure hyperglyceridaemia
0.000 0.241 0.759
E78.4 Other hyperlipidaemia
0.000 0.246 0.754
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.248 0.752
L40.1 Generalised pustular psoriasis
0.000 0.253 0.747
E11.2 With renal complications
0.000 0.254 0.746
E10.6 With other specified complications
0.000 0.257 0.743
E11.1 With ketoacidosis
0.000 0.257 0.743
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.262 0.738
E78.5 Hyperlipidaemia, unspecified
0.000 0.272 0.728
E78.6 Lipoprotein deficiency
0.000 0.274 0.726
E14.9 Without complications
0.000 0.280 0.720
E74 Other disorders of carbohydrate metabolism
0.000 0.281 0.719
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E03.5 Myxoedema coma
0.000 0.283 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E03.8 Other specified hypothyroidism
0.000 0.286 0.714
E10.7 With multiple complications
0.000 0.287 0.713
E11.7 With multiple complications
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.294 0.706
L40.4 Guttate psoriasis
0.000 0.294 0.706
L40.2 Acrodermatitis continua
0.000 0.294 0.706
E07 Other disorders of thyroid
0.000 0.296 0.704
E79 Disorders of purine and pyrimidine metabolism
0.000 0.296 0.704
E77 Disorders of glycoprotein metabolism
0.000 0.296 0.704
E76 Disorders of glycosaminoglycan metabolism
0.000 0.296 0.704
E72 Other disorders of amino-acid metabolism
0.000 0.296 0.704
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.296 0.704
E70 Disorders of aromatic amino-acid metabolism
0.000 0.296 0.704
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.296 0.704
E05.5 Thyroid crisis or storm
0.000 0.303 0.697
E05.4 Thyrotoxicosis factitia
0.000 0.303 0.697
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.303 0.697
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.303 0.697
G37.8 Other specified demyelinating diseases of central nervous system
0.696 0.304 0.000
E14.1 With ketoacidosis
0.000 0.308 0.692
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.313 0.687
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.313 0.687
E14.5 With peripheral circulatory complications
0.000 0.315 0.684
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.321 0.679
E84 Cystic fibrosis
0.000 0.324 0.676
G36 Other acute disseminated demyelination
0.671 0.329 0.000
E10.0 With coma
0.000 0.335 0.665
K51.9 Ulcerative colitis, unspecified
0.662 0.338 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.341 0.659
K51 Ulcerative colitis
0.658 0.342 0.000
E14.4 With neurological complications
0.000 0.345 0.655
E14.7 With multiple complications
0.000 0.351 0.648
E14.0 With coma
0.000 0.351 0.648
L40-L45 Papulosquamous disorders
0.000 0.355 0.645
E03.1 Congenital hypothyroidism without goitre
0.000 0.362 0.638
K51.2 Ulcerative (chronic) proctitis
0.635 0.365 0.000
E40-E46 Malnutrition
0.000 0.365 0.635
E13.9 Without complications
0.000 0.379 0.621
E14.6 With other specified complications
0.000 0.380 0.620
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.380 0.620
E10.5 With peripheral circulatory complications
0.000 0.389 0.611
E14.2 Withrenal complications
0.000 0.397 0.603
K51.5 Mucosal proctocolitis
0.603 0.397 0.000
G37.5 Concentric sclerosis [Balo]
0.602 0.398 0.000
G37.4 Subacute necrotising myelitis
0.602 0.398 0.000
G37.2 Central pontine myelinolysis
0.602 0.398 0.000
G37.1 Central demyelination of corpus callosum
0.602 0.398 0.000
G37.0 Diffuse sclerosis
0.602 0.398 0.000
E11.8 With unspecified complications
0.000 0.401 0.599
E14.8 With unspecified complications
0.000 0.404 0.596
K51.3 Ulcerative (chronic) rectosigmoiditis
0.593 0.407 0.000
E80.2 Other porphyria
0.000 0.412 0.588
E80.4 Gilbert's syndrome
0.000 0.416 0.584
E85 Amyloidosis
0.000 0.416 0.584
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.583 0.417 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.419 0.581
E80.6 Other disorders of bilirubin metabolism
0.000 0.419 0.581
E10.2 With renal complications
0.000 0.420 0.580
E10.1 With ketoacidosis
0.000 0.421 0.579
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.421 0.579
L43 Lichen planus
0.000 0.439 0.561
E73 Lactose intolerance
0.000 0.442 0.558
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.444 0.556
E80.5 Crigler-Najjar syndrome
0.000 0.444 0.556
E80.3 Defects of catalase and peroxydase
0.000 0.444 0.556
E80.0 Hereditary erythropoietic porphyria
0.000 0.444 0.556
E80.1 Porphyria cutanea tarda
0.000 0.446 0.554
E16 Other disorders of pancreatic internal secretion
0.000 0.449 0.551
E05.8 Other thyrotoxicosis
0.000 0.450 0.550
E13.8 With unspecified complications
0.000 0.454 0.546
E13.7 With multiple complications
0.000 0.454 0.546
E13.6 With other specified complications
0.000 0.454 0.546
E13.5 With peripheral circulatory complications
0.000 0.454 0.546
E13.4 With neurological complications
0.000 0.454 0.546
E13.2 With renal complications
0.000 0.454 0.546
E13.1 With ketoacidosis
0.000 0.454 0.546
E13.0 With coma
0.000 0.454 0.546
I25 Chronic ischaemic heart disease
0.000 0.455 0.545
K51.4 Pseudopolyposis of colon
0.544 0.456 0.000
E83 Disorders of mineral metabolism
0.463 0.457 0.081
I25.5 Ischaemic cardiomyopathy
0.000 0.465 0.535
K51.1 Ulcerative (chronic) ileocolitis
0.530 0.470 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.471 0.529
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.471 0.528
G36.0 Neuromyelitis optica [Devic]
0.526 0.474 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.475 0.525
I20-I25 Ischaemic heart diseases
0.000 0.477 0.523
L43.9 Lichen planus, unspecified
0.000 0.478 0.522
I25.1 Atherosclerotic heart disease
0.000 0.483 0.517
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.484 0.515
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.484 0.515
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.484 0.515
E74.2 Disorders of galactose metabolism
0.000 0.484 0.515
E74.1 Disorders of fructose metabolism
0.000 0.484 0.515
I22 Subsequent myocardial infarction
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.493 0.507
E07.1 Dyshormogenetic goitre
0.000 0.495 0.505
E07.0 Hypersecretion of calcitonin
0.000 0.495 0.505
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.495 0.504
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.495 0.504
E70.3 Albinism
0.000 0.495 0.504
E70.2 Disorders of tyrosine metabolism
0.000 0.495 0.504
E70.1 Other hyperphenylalaninaemias
0.000 0.495 0.504
E70.0 Classical phenylketonuria
0.000 0.495 0.504
E71.3 Disorders of fatty-acid metabolism
0.000 0.495 0.504
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.495 0.504
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.495 0.504
E71.0 Maple-syrup-urine disease
0.000 0.495 0.504
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.495 0.504
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.495 0.504
E72.5 Disorders of glycine metabolism
0.000 0.495 0.504
E72.4 Disorders of ornithine metabolism
0.000 0.495 0.504
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.495 0.504
E72.2 Disorders of urea cycle metabolism
0.000 0.495 0.504
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.495 0.504
E72.0 Disorders of amino-acid transport
0.000 0.495 0.504
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.495 0.504
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.495 0.504
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.495 0.504
E76.2 Other mucopolysaccharidoses
0.000 0.495 0.504
E76.1 Mucopolysaccharidosis, type II
0.000 0.495 0.504
E76.0 Mucopolysaccharidosis, type I
0.000 0.495 0.504
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.495 0.504
E77.8 Other disorders of glycoprotein metabolism
0.000 0.495 0.504
E77.1 Defects in glycoprotein degradation
0.000 0.495 0.504
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.495 0.504
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.495 0.504
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.495 0.504
E79.1 Lesch-Nyhan syndrome
0.000 0.495 0.504
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.495 0.504
E88 Other metabolic disorders
0.000 0.496 0.504
E13.3 With ophthalmic complications
0.000 0.500 0.500
L42 Pityriasis rosea
0.000 0.504 0.496
E75.6 Lipid storage disorder, unspecified
0.000 0.507 0.493
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.507 0.493
E75.3 Sphingolipidosis, unspecified
0.000 0.507 0.493
E75.2 Other sphingolipidosis
0.000 0.507 0.493
E75.1 Other gangliosidosis
0.000 0.507 0.493
E75.0 GM2 gangliosidosis
0.000 0.507 0.493
E84.8 Cystic fibrosis with other manifestations
0.000 0.515 0.485
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.515 0.485
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.515 0.485
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.516 0.484
E10.4 With neurological complications
0.000 0.517 0.482
G36.9 Acute disseminated demyelination, unspecified
0.481 0.519 0.000
G36.8 Other specified acute disseminated demyelination
0.481 0.519 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.481 0.519 0.000
E75.5 Other lipid storage disorders
0.000 0.524 0.476
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.524 0.476
I24 Other acute ischaemic heart diseases
0.000 0.525 0.475
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.527 0.473
E07.8 Other specified disorders of thyroid
0.000 0.532 0.468
K51.8 Other ulcerative colitis
0.467 0.533 0.000
I25.2 Old myocardial infarction
0.000 0.533 0.467
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.534 0.466
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.534 0.466
L44 Other papulosquamous disorders
0.000 0.537 0.463
L41 Parapsoriasis
0.000 0.537 0.463
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.537 0.463
E84.9 Cystic fibrosis, unspecified
0.000 0.542 0.458
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.544 0.455
E45 Retarded development following protein-energy malnutrition
0.000 0.544 0.455
E43 Unspecified severe protein-energy malnutrition
0.000 0.544 0.455
E42 Marasmic kwashiorkor
0.000 0.544 0.455
E41 Nutritional marasmus
0.000 0.544 0.455
E40 Kwashiorkor
0.000 0.544 0.455
E11.5 With peripheral circulatory complications
0.000 0.548 0.452
E11.6 With other specified complications
0.000 0.552 0.448
E74.0 Glycogen storage disease
0.000 0.554 0.445
I23 Certain current complications following acute myocardial infarction
0.000 0.557 0.443
E16.1 Other hypoglycaemia
0.000 0.560 0.440
K90 Intestinal malabsorption
0.000 0.564 0.435
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.567 0.433
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.567 0.433
E85.8 Other amyloidosis
0.000 0.581 0.419
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.581 0.419
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.581 0.419
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.581 0.419
E11.4 With neurological complications
0.000 0.592 0.407
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.593 0.407
I22.8 Subsequent myocardial infarction of other sites
0.000 0.596 0.404
L43.3 Subacute (active) lichen planus
0.000 0.597 0.402
L43.2 Lichenoid drug reaction
0.000 0.597 0.402
L43.1 Bullous lichen planus
0.000 0.597 0.402
L43.0 Hypertrophic lichen planus
0.000 0.597 0.402
E73.8 Other lactose intolerance
0.000 0.600 0.400
E73.1 Secondary lactase deficiency
0.000 0.600 0.400
E73.0 Congenital lactase deficiency
0.000 0.600 0.400
K51.0 Ulcerative (chronic) enterocolitis
0.400 0.600 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.602 0.397
E83.3 Disorders of phosphorus metabolism
0.367 0.603 0.030
E85.9 Amyloidosis, unspecified
0.000 0.604 0.396
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.605 0.395
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.605 0.395
E16.4 Abnormal secretion of gastrin
0.000 0.605 0.395
E16.3 Increased secretion of glucagon
0.000 0.605 0.395
M06 Other rheumatoid arthritis
0.000 0.607 0.393
I25.6 Silent myocardial ischaemia
0.000 0.609 0.391
E83.9 Disorder of mineral metabolism, unspecified
0.332 0.610 0.058
E83.8 Other disorders of mineral metabolism
0.332 0.610 0.058
E83.2 Disorders of zinc metabolism
0.332 0.610 0.058
E83.0 Disorders of copper metabolism
0.332 0.610 0.058
E85.4 Organ-limited amyloidosis
0.000 0.613 0.386
I23.8 Other current complications following acute myocardial infarction
0.000 0.615 0.385
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.615 0.385
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.620 0.380
I21 Acute myocardial infarction
0.000 0.622 0.378
E65-E68 Obesity and other hyperalimentation
0.000 0.624 0.376
E85.3 Secondary systemic amyloidosis
0.000 0.625 0.375
E46 Unspecified protein-energy malnutrition
0.000 0.625 0.375
E50-E64 Other nutritional deficiencies
0.001 0.628 0.371
I25.3 Aneurysm of heart
0.000 0.629 0.370
E88.2 Lipomatosis, not elsewhere classified
0.000 0.634 0.365
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.637 0.363
E88.9 Metabolic disorder, unspecified
0.000 0.638 0.361
E88.8 Other specified metabolic disorders
0.000 0.638 0.361
E88.3 Tumour lysis syndrome
0.000 0.638 0.361
E89.3 Postprocedural hypopituitarism
0.000 0.640 0.360
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.642 0.358
E06 Thyroiditis
0.001 0.646 0.354
I25.4 Coronary artery aneurysm
0.000 0.647 0.353
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.652 0.348
E89.4 Postprocedural ovarian failure
0.000 0.654 0.346
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.658 0.342
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.658 0.342
E89.5 Postprocedural testicular hypofunction
0.000 0.658 0.342
E89.1 Postprocedural hypoinsulinaemia
0.000 0.658 0.342
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.660 0.340
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.667 0.333
L41.9 Parapsoriasis, unspecified
0.000 0.668 0.332
L41.8 Other parapsoriasis
0.000 0.668 0.332
L41.5 Retiform parapsoriasis
0.000 0.668 0.332
L41.4 Large plaque parapsoriasis
0.000 0.668 0.332
L41.3 Small plaque parapsoriasis
0.000 0.668 0.332
L41.2 Lymphomatoid papulosis
0.000 0.668 0.332
L41.1 Pityriasis lichenoides chronica
0.000 0.668 0.332
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.668 0.332
L44.9 Papulosquamous disorder, unspecified
0.000 0.668 0.332
L44.8 Other specified papulosquamous disorders
0.000 0.668 0.332
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.668 0.332
L44.3 Lichen ruber moniliformis
0.000 0.668 0.332
L44.2 Lichen striatus
0.000 0.668 0.332
L44.1 Lichen nitidus
0.000 0.668 0.332
L44.0 Pityriasis rubra pilaris
0.000 0.668 0.332
E44.1 Mild protein-energy malnutrition
0.000 0.673 0.327
E44.0 Moderate protein-energy malnutrition
0.000 0.673 0.327
M06.3 Rheumatoid nodule
0.000 0.677 0.323
L43.8 Other lichen planus
0.000 0.679 0.321
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.682 0.317
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.682 0.317
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.682 0.317
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.682 0.317
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.682 0.317
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.682 0.317
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.682 0.317
I21.9 Acute myocardial infarction, unspecified
0.000 0.683 0.317
M06.4 Inflammatory polyarthropathy
0.000 0.685 0.315
I21.4 Acute subendocardial myocardial infarction
0.000 0.686 0.314
K90.3 Pancreatic steatorrhoea
0.000 0.687 0.312
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.687 0.312
K90.1 Tropical sprue
0.000 0.687 0.312
E16.2 Hypoglycaemia, unspecified
0.000 0.697 0.303
K90.8 Other intestinal malabsorption
0.000 0.711 0.289
K90.9 Intestinal malabsorption, unspecified
0.000 0.711 0.289
M06.2 Rheumatoid bursitis
0.000 0.718 0.282
M06.1 Adult-onset Still's disease
0.000 0.718 0.282
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.720 0.280
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.726 0.274
I24.1 Dressler's syndrome
0.000 0.727 0.273
E89.2 Postprocedural hypoparathyroidism
0.000 0.728 0.271
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.729 0.271
E61 Deficiency of other nutrient elements
0.001 0.729 0.270
M06.8 Other specified rheumatoid arthritis
0.000 0.730 0.270
I24.8 Other forms of acute ischaemic heart disease
0.000 0.730 0.270
E67 Other hyperalimentation
0.000 0.730 0.270
E68 Sequelae of hyperalimentation
0.000 0.730 0.270
E83.4 Disorders of magnesium metabolism
0.233 0.733 0.034
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.733 0.266
E63 Other nutritional deficiencies
0.001 0.733 0.266
E56 Other vitamin deficiencies
0.001 0.733 0.266
E50 Vitamin A deficiency
0.001 0.733 0.266
E60 Dietary zinc deficiency
0.001 0.733 0.266
E59 Dietary selenium deficiency
0.001 0.733 0.266
E58 Dietary calcium deficiency
0.001 0.733 0.266
E54 Ascorbic acid deficiency
0.001 0.733 0.266
E52 Niacin deficiency [pellagra]
0.001 0.733 0.266
E51 Thiamine deficiency
0.001 0.736 0.263
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.740 0.260
M06.34 Rheumatoid nodule (Hand)
0.000 0.742 0.258
E73.9 Lactose intolerance, unspecified
0.001 0.745 0.254
E06.5 Other chronic thyroiditis
0.001 0.746 0.254
E06.4 Drug-induced thyroiditis
0.001 0.746 0.254
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.746 0.254
E06.0 Acute thyroiditis
0.001 0.746 0.254
E20-E35 Disorders of other endocrine glands
0.000 0.754 0.246
E06.1 Subacute thyroiditis
0.001 0.765 0.234
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.768 0.232
M06.38 Rheumatoid nodule (Other)
0.000 0.768 0.232
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.768 0.232
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.768 0.232
M06.33 Rheumatoid nodule (Forearm)
0.000 0.768 0.232
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.768 0.232
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.774 0.226
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.774 0.226
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.774 0.226
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.774 0.226
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.774 0.226
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.774 0.226
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.774 0.226
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.774 0.226
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.774 0.226
E65 Localised adiposity
0.000 0.776 0.224
E83.5 Disorders of calcium metabolism
0.214 0.776 0.010
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.780 0.220
E61.1 Iron deficiency
0.000 0.789 0.211
E28 Ovarian dysfunction
0.000 0.789 0.211
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.789 0.211
M06.0 Seronegative rheumatoid arthritis
0.000 0.790 0.210
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.790 0.210
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.791 0.208
E11.3 With ophthalmic complications
0.000 0.795 0.205
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.797 0.202
M06.18 Adult-onset Still's disease (Other)
0.000 0.797 0.202
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.797 0.202
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.797 0.202
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.797 0.202
M06.14 Adult-onset Still's disease (Hand)
0.000 0.797 0.202
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.797 0.202
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.797 0.202
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.797 0.202
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.797 0.202
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.797 0.202
M06.28 Rheumatoid bursitis (Other)
0.000 0.797 0.202
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.797 0.202
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.797 0.202
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.797 0.202
M06.24 Rheumatoid bursitis (Hand)
0.000 0.797 0.202
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.797 0.202
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.797 0.202
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.797 0.202
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.797 0.202
E28.2 Polycystic ovarian syndrome
0.000 0.805 0.195
E61.9 Deficiency of nutrient element, unspecified
0.001 0.806 0.194
E61.8 Deficiency of other specified nutrient elements
0.001 0.806 0.194
E61.7 Deficiency of multiple nutrient elements
0.001 0.806 0.194
E61.6 Vanadium deficiency
0.001 0.806 0.194
E61.5 Molybdenum deficiency
0.001 0.806 0.194
E61.4 Chromium deficiency
0.001 0.806 0.194
E61.3 Manganese deficiency
0.001 0.806 0.194
E61.0 Copper deficiency
0.001 0.806 0.194
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.806 0.194
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.806 0.194
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.806 0.194
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.806 0.194
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.806 0.194
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.806 0.194
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.806 0.194
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.806 0.194
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.806 0.194
E67.8 Other specified hyperalimentation
0.000 0.806 0.193
E67.3 Hypervitaminosis D
0.000 0.806 0.193
E67.2 Megavitamin-B6 syndrome
0.000 0.806 0.193
E67.1 Hypercarotenaemia
0.000 0.806 0.193
E67.0 Hypervitaminosis A
0.000 0.806 0.193
E50.9 Vitamin A deficiency, unspecified
0.001 0.809 0.191
E50.8 Other manifestations of vitamin A deficiency
0.001 0.809 0.191
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.809 0.191
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.809 0.191
E50.5 Vitamin A deficiency with night blindness
0.001 0.809 0.191
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.809 0.191
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.809 0.191
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.809 0.191
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.809 0.191
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.809 0.191
E56.9 Vitamin deficiency, unspecified
0.001 0.809 0.191
E56.8 Deficiency of other vitamins
0.001 0.809 0.191
E56.1 Deficiency of vitamin K
0.001 0.809 0.191
E56.0 Deficiency of vitamin E
0.001 0.809 0.191
E63.9 Nutritional deficiency, unspecified
0.001 0.809 0.191
E63.8 Other specified nutritional deficiencies
0.001 0.809 0.191
E63.1 Imbalance of constituents of food intake
0.001 0.809 0.191
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.809 0.191
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.809 0.191
E64.8 Sequelae of other nutritional deficiencies
0.001 0.809 0.191
E64.3 Sequelae of rickets
0.001 0.809 0.191
E64.2 Sequelae of vitamin C deficiency
0.001 0.809 0.191
E64.1 Sequelae of vitamin A deficiency
0.001 0.809 0.191
E64.0 Sequelae of protein-energy malnutrition
0.001 0.809 0.191
E51.9 Thiamine deficiency, unspecified
0.001 0.811 0.189
E51.8 Other manifestations of thiamine deficiency
0.001 0.811 0.189
E51.1 Beriberi
0.001 0.811 0.189
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.812 0.188
E23 Hypofunction and other disorders of pituitary gland
0.000 0.812 0.188
E24 Cushing's syndrome
0.000 0.813 0.187
E51.2 Wernicke's encephalopathy
0.001 0.814 0.186
E26 Hyperaldosteronism
0.000 0.817 0.183
E55 Vitamin D deficiency
0.001 0.818 0.182
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.818 0.182
E61.2 Magnesium deficiency
0.001 0.822 0.177
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.823 0.177
E32 Diseases of thymus
0.000 0.823 0.177
E31 Polyglandular dysfunction
0.000 0.823 0.177
E30 Disorders of puberty, not elsewhere classified
0.000 0.823 0.177
E25 Adrenogenital disorders
0.000 0.823 0.177
E06.9 Thyroiditis, unspecified
0.001 0.829 0.170
E23.7 Disorder of pituitary gland, unspecified
0.000 0.845 0.155
E28.9 Ovarian dysfunction, unspecified
0.000 0.848 0.151
E28.8 Other ovarian dysfunction
0.000 0.848 0.151
E28.1 Androgen excess
0.000 0.848 0.151
E28.0 Oestrogen excess
0.000 0.848 0.151
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.849 0.151
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.849 0.151
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.849 0.151
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.849 0.151
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.849 0.151
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.849 0.151
E29 Testicular dysfunction
0.000 0.850 0.149
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.851 0.149
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.854 0.146
E24.9 Cushing's syndrome, unspecified
0.000 0.856 0.144
E20 Hypoparathyroidism
0.000 0.856 0.144
E06.3 Autoimmune thyroiditis
0.001 0.857 0.142
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.859 0.140

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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