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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132572
log Bayes Factor = 39.1162
Chromosome 6   position 30,861,729  (GRCh37) Explore rs3132572 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E11.9 Without complications
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.011 0.989
E14 Unspecified diabetes mellitus
0.000 0.017 0.983
G35-G37 Demyelinating diseases of the central nervous system
0.980 0.020 0.000
K90.0 Coeliac disease
0.000 0.028 0.972
E14.9 Without complications
0.000 0.044 0.956
E10.1 With ketoacidosis
0.000 0.047 0.953
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.054 0.945
E70-E90 Metabolic disorders
0.002 0.056 0.942
E11.5 With peripheral circulatory complications
0.000 0.060 0.940
G37 Other demyelinating diseases of central nervous system
0.928 0.072 0.000
E10.4 With neurological complications
0.000 0.076 0.924
E78.5 Hyperlipidaemia, unspecified
0.000 0.076 0.924
Chapter VI Diseases of the nervous system
0.902 0.097 0.000
L40.0 Psoriasis vulgaris
0.000 0.099 0.901
E10.2 With renal complications
0.000 0.101 0.899
E11.4 With neurological complications
0.000 0.108 0.892
E78.2 Mixed hyperlipidaemia
0.000 0.108 0.892
G37.9 Demyelinating disease of central nervous system, unspecified
0.884 0.116 0.000
E11.6 With other specified complications
0.000 0.123 0.877
I20-I25 Ischaemic heart diseases
0.000 0.126 0.874
I24 Other acute ischaemic heart diseases
0.000 0.128 0.872
G40-G47 Episodic and paroxysmal disorders
0.858 0.142 0.000
E14.3 With ophthalmic complications
0.000 0.144 0.856
I21 Acute myocardial infarction
0.000 0.144 0.856
G00-G09 Inflammatory diseases of the central nervous system
0.853 0.147 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.149 0.851
E13 Other specified diabetes mellitus
0.000 0.169 0.831
G40 Epilepsy
0.827 0.173 0.000
G30-G32 Other degenerative diseases of the nervous system
0.826 0.174 0.000
I25 Chronic ischaemic heart disease
0.000 0.174 0.826
I24.8 Other forms of acute ischaemic heart disease
0.000 0.177 0.823
E11.0 With coma
0.000 0.180 0.820
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.195 0.805
I22 Subsequent myocardial infarction
0.000 0.195 0.805
G20-G26 Extrapyramidal and movement disorders
0.804 0.196 0.000
E10.5 With peripheral circulatory complications
0.000 0.198 0.802
E11.1 With ketoacidosis
0.000 0.198 0.802
I21.4 Acute subendocardial myocardial infarction
0.000 0.211 0.789
I21.9 Acute myocardial infarction, unspecified
0.000 0.211 0.789
I10-I15 Hypertensive diseases
0.000 0.213 0.787
I10 Essential (primary) hypertension
0.000 0.213 0.787
I12 Hypertensive renal disease
0.000 0.216 0.784
G46 Vascular syndromes of brain in cerebrovascular diseases
0.782 0.218 0.000
E11.2 With renal complications
0.000 0.221 0.779
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.222 0.778
I12.0 Hypertensive renal disease with renal failure
0.000 0.224 0.776
E78.1 Pure hyperglyceridaemia
0.000 0.230 0.770
E20-E35 Disorders of other endocrine glands
0.000 0.230 0.770
I25.1 Atherosclerotic heart disease
0.000 0.231 0.769
E85 Amyloidosis
0.001 0.237 0.762
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.761 0.239 0.000
E10.6 With other specified complications
0.000 0.249 0.751
I25.2 Old myocardial infarction
0.000 0.258 0.742
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.259 0.741
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.262 0.738
E78.8 Other disorders of lipoprotein metabolism
0.000 0.262 0.738
G43 Migraine
0.734 0.266 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.731 0.269 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.729 0.271 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.728 0.272 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.272 0.728
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.723 0.277 0.000
G03 Meningitis due to other and unspecified causes
0.722 0.278 0.000
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
L40.8 Other psoriasis
0.000 0.284 0.716
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.712 0.287 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.290 0.710
E78.6 Lipoprotein deficiency
0.000 0.291 0.709
E78.3 Hyperchylomicronaemia
0.000 0.291 0.709
E13.9 Without complications
0.000 0.291 0.709
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.706 0.294 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.295 0.705
E14.8 With unspecified complications
0.000 0.295 0.705
E14.7 With multiple complications
0.000 0.295 0.705
E14.6 With other specified complications
0.000 0.295 0.705
E14.5 With peripheral circulatory complications
0.000 0.295 0.705
E14.4 With neurological complications
0.000 0.295 0.705
E14.2 Withrenal complications
0.000 0.295 0.705
E14.1 With ketoacidosis
0.000 0.295 0.705
E14.0 With coma
0.000 0.295 0.705
G36 Other acute disseminated demyelination
0.702 0.297 0.000
G20 Parkinson's disease
0.700 0.300 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.698 0.302 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.697 0.303 0.000
E74 Other disorders of carbohydrate metabolism
0.001 0.306 0.692
E24 Cushing's syndrome
0.000 0.316 0.684
E40-E46 Malnutrition
0.000 0.317 0.683
G46.7 Other lacunar syndromes
0.682 0.318 0.000
E83 Disorders of mineral metabolism
0.524 0.319 0.157
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.322 0.676
E79 Disorders of purine and pyrimidine metabolism
0.001 0.323 0.675
E77 Disorders of glycoprotein metabolism
0.001 0.323 0.675
E76 Disorders of glycosaminoglycan metabolism
0.001 0.323 0.675
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.323 0.675
E72 Other disorders of amino-acid metabolism
0.001 0.323 0.675
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.323 0.675
E70 Disorders of aromatic amino-acid metabolism
0.001 0.323 0.675
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.323 0.675
E78.4 Other hyperlipidaemia
0.000 0.325 0.675
I25.5 Ischaemic cardiomyopathy
0.000 0.326 0.674
L40-L45 Papulosquamous disorders
0.000 0.332 0.668
G80-G83 Cerebral palsy and other paralytic syndromes
0.666 0.334 0.000
G37.5 Concentric sclerosis [Balo]
0.665 0.334 0.000
G37.4 Subacute necrotising myelitis
0.665 0.334 0.000
G37.2 Central pontine myelinolysis
0.665 0.334 0.000
G37.1 Central demyelination of corpus callosum
0.665 0.334 0.000
G37.0 Diffuse sclerosis
0.665 0.334 0.000
G46.4 Cerebellar stroke syndrome
0.663 0.337 0.000
I23 Certain current complications following acute myocardial infarction
0.000 0.339 0.661
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.339 0.661
G24 Dystonia
0.654 0.346 0.000
G44 Other headache syndromes
0.652 0.348 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.351 0.649
G40.7 Petit mal, unspecified, without grand mal seizures
0.648 0.351 0.000
G40.9 Epilepsy, unspecified
0.648 0.352 0.000
E22 Hyperfunction of pituitary gland
0.000 0.353 0.647
I15 Secondary hypertension
0.000 0.353 0.646
E73 Lactose intolerance
0.001 0.355 0.644
G70-G73 Diseases of myoneural junction and muscle
0.643 0.357 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.642 0.358 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.360 0.640
E85.9 Amyloidosis, unspecified
0.001 0.365 0.635
G31.2 Degeneration of nervous system due to alcohol
0.635 0.365 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.633 0.367 0.000
G30 Alzheimer's disease
0.631 0.369 0.000
G03.9 Meningitis, unspecified
0.628 0.372 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.373 0.626
E84 Cystic fibrosis
0.002 0.376 0.623
E89.3 Postprocedural hypopituitarism
0.000 0.376 0.623
E24.9 Cushing's syndrome, unspecified
0.000 0.377 0.623
E11.8 With unspecified complications
0.000 0.377 0.623
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.619 0.381 0.000
Chapter IX Diseases of the circulatory system
0.000 0.382 0.618
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.383 0.617
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.383 0.617
G41 Status epilepticus
0.616 0.384 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.386 0.614
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.611 0.389 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.611 0.389 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.611 0.389 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.390 0.610
G43.8 Other migraine
0.610 0.390 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.390 0.610
I24.1 Dressler's syndrome
0.000 0.395 0.605
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.601 0.399 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.601 0.399 0.000
G00 Bacterial meningitis, not elsewhere classified
0.597 0.403 0.000
E13.8 With unspecified complications
0.000 0.404 0.595
E13.7 With multiple complications
0.000 0.404 0.595
E13.6 With other specified complications
0.000 0.404 0.595
E13.5 With peripheral circulatory complications
0.000 0.404 0.595
E13.4 With neurological complications
0.000 0.404 0.595
E13.3 With ophthalmic complications
0.000 0.404 0.595
E13.2 With renal complications
0.000 0.404 0.595
E13.1 With ketoacidosis
0.000 0.404 0.595
E13.0 With coma
0.000 0.404 0.595
G40.4 Other generalised epilepsy and epileptic syndromes
0.593 0.407 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.592 0.407 0.000
I25.6 Silent myocardial ischaemia
0.000 0.408 0.592
E29 Testicular dysfunction
0.000 0.408 0.592
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.412 0.588
G43.9 Migraine, unspecified
0.585 0.415 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.580 0.420 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.420 0.580
E15 Nondiabetic hypoglycaemic coma
0.000 0.423 0.577
G23 Other degenerative diseases of basal ganglia
0.576 0.424 0.000
G21 Secondary Parkinsonism
0.576 0.424 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.576 0.424 0.000
G22 Parkinsonism in diseases classified elsewhere
0.576 0.424 0.000
M06 Other rheumatoid arthritis
0.000 0.425 0.575
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.425 0.575
G83 Other paralytic syndromes
0.573 0.427 0.000
L43 Lichen planus
0.000 0.429 0.571
G25 Other extrapyramidal and movement disorders
0.567 0.433 0.000
G06.1 Intraspinal abscess and granuloma
0.566 0.434 0.000
I13 Hypertensive heart and renal disease
0.000 0.436 0.564
E28 Ovarian dysfunction
0.000 0.436 0.564
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.561 0.439 0.000
G46.6 Pure sensory lacunar syndrome
0.561 0.439 0.000
G46.5 Pure motor lacunar syndrome
0.561 0.439 0.000
G46.3 Brain stem stroke syndrome
0.561 0.439 0.000
G46.2 Posterior cerebral artery syndrome
0.561 0.439 0.000
G46.1 Anterior cerebral artery syndrome
0.561 0.439 0.000
G46.0 Middle cerebral artery syndrome
0.561 0.439 0.000
I11 Hypertensive heart disease
0.000 0.442 0.557
G24.9 Dystonia, unspecified
0.555 0.445 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.446 0.554
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.447 0.553
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.448 0.552
E32 Diseases of thymus
0.000 0.448 0.552
E31 Polyglandular dysfunction
0.000 0.448 0.552
E30 Disorders of puberty, not elsewhere classified
0.000 0.448 0.552
E25 Adrenogenital disorders
0.000 0.448 0.552
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.451 0.549
G40.5 Special epileptic syndromes
0.549 0.451 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.452 0.548
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.453 0.547
E85.8 Other amyloidosis
0.001 0.453 0.546
E85.3 Secondary systemic amyloidosis
0.001 0.453 0.546
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.453 0.546
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.453 0.546
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.453 0.546
I15.1 Hypertension secondary to other renal disorders
0.000 0.454 0.546
G31.1 Senile degeneration of brain, not elsewhere classified
0.546 0.454 0.000
E85.4 Organ-limited amyloidosis
0.001 0.457 0.542
G44.0 Cluster headache syndrome
0.542 0.458 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.460 0.540
G30.8 Other Alzheimer's disease
0.533 0.467 0.000
G43.0 Migraine without aura [common migraine]
0.531 0.469 0.000
G06.2 Extradural and subdural abscess, unspecified
0.527 0.473 0.000
G43.3 Complicated migraine
0.526 0.474 0.000
G43.2 Status migrainosus
0.526 0.474 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.525 0.475 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.476 0.524
G40.8 Other epilepsy
0.523 0.477 0.000
I20 Angina pectoris
0.000 0.478 0.522
G43.1 Migraine with aura [classical migraine]
0.520 0.480 0.000
G24.8 Other dystonia
0.520 0.480 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.481 0.519
G03.8 Meningitis due to other specified causes
0.517 0.482 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.517 0.482 0.000
G03.1 Chronic meningitis
0.517 0.482 0.000
G03.0 Nonpyogenic meningitis
0.517 0.482 0.000
E23.0 Hypopituitarism
0.000 0.484 0.516
G82 Paraplegia and tetraplegia
0.515 0.485 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
K90 Intestinal malabsorption
0.000 0.487 0.513
G44.2 Tension-type headache
0.512 0.488 0.000
I25.4 Coronary artery aneurysm
0.000 0.489 0.511
I23.8 Other current complications following acute myocardial infarction
0.000 0.491 0.509
G31.0 Circumscribed brain atrophy
0.509 0.491 0.000
E50-E64 Other nutritional deficiencies
0.000 0.493 0.506
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.506 0.493 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.506 0.493 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.506 0.493 0.000
L43.9 Lichen planus, unspecified
0.000 0.494 0.506
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.495 0.505
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.495 0.505
E16.4 Abnormal secretion of gastrin
0.000 0.495 0.505
E16.3 Increased secretion of glucagon
0.000 0.495 0.505
E16.1 Other hypoglycaemia
0.000 0.495 0.505
G70 Myasthenia gravis and other myoneural disorders
0.505 0.495 0.000
G06.0 Intracranial abscess and granuloma
0.504 0.496 0.000
G36.9 Acute disseminated demyelination, unspecified
0.504 0.496 0.000
G36.8 Other specified acute disseminated demyelination
0.504 0.496 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.504 0.496 0.000
G36.0 Neuromyelitis optica [Devic]
0.504 0.496 0.000
I25.3 Aneurysm of heart
0.000 0.496 0.504
M07.3 Other psoriatic arthropathies
0.000 0.496 0.504
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.503 0.496
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.503 0.496
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.503 0.496
E74.2 Disorders of galactose metabolism
0.001 0.503 0.496
E74.1 Disorders of fructose metabolism
0.001 0.503 0.496
E74.0 Glycogen storage disease
0.001 0.503 0.496
I22.8 Subsequent myocardial infarction of other sites
0.000 0.504 0.496
E46 Unspecified protein-energy malnutrition
0.000 0.505 0.494
E20 Hypoparathyroidism
0.000 0.507 0.493
G83.4 Cauda equina syndrome
0.493 0.507 0.000
E26 Hyperaldosteronism
0.000 0.508 0.491
E24.8 Other Cushing's syndrome
0.000 0.509 0.491
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.509 0.491
E24.3 Ectopic ACTH syndrome
0.000 0.509 0.491
E24.2 Drug-induced Cushing's syndrome
0.000 0.509 0.491
E24.1 Nelson's syndrome
0.000 0.509 0.491
E24.0 Pituitary-dependent Cushing's disease
0.000 0.509 0.491
G72 Other myopathies
0.490 0.509 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.510 0.490
E45 Retarded development following protein-energy malnutrition
0.000 0.510 0.490
E43 Unspecified severe protein-energy malnutrition
0.000 0.510 0.490
E42 Marasmic kwashiorkor
0.000 0.510 0.490
E41 Nutritional marasmus
0.000 0.510 0.490
E40 Kwashiorkor
0.000 0.510 0.490
E83.9 Disorder of mineral metabolism, unspecified
0.376 0.512 0.112
E83.8 Other disorders of mineral metabolism
0.376 0.512 0.112
E83.2 Disorders of zinc metabolism
0.376 0.512 0.112
E83.0 Disorders of copper metabolism
0.376 0.512 0.112
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.001 0.514 0.485
E89.8 Other postprocedural endocrine and metabolic disorders
0.001 0.514 0.485
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.514 0.485
E89.5 Postprocedural testicular hypofunction
0.001 0.514 0.485
E89.4 Postprocedural ovarian failure
0.001 0.514 0.485
E89.1 Postprocedural hypoinsulinaemia
0.001 0.514 0.485
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.515 0.484
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.515 0.484
E70.3 Albinism
0.001 0.515 0.484
E70.2 Disorders of tyrosine metabolism
0.001 0.515 0.484
E70.1 Other hyperphenylalaninaemias
0.001 0.515 0.484
E70.0 Classical phenylketonuria
0.001 0.515 0.484
E71.3 Disorders of fatty-acid metabolism
0.001 0.515 0.484
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.515 0.484
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.515 0.484
E71.0 Maple-syrup-urine disease
0.001 0.515 0.484
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.515 0.484
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.515 0.484
E72.5 Disorders of glycine metabolism
0.001 0.515 0.484
E72.4 Disorders of ornithine metabolism
0.001 0.515 0.484
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.515 0.484
E72.2 Disorders of urea cycle metabolism
0.001 0.515 0.484
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.515 0.484
E72.0 Disorders of amino-acid transport
0.001 0.515 0.484
E75.6 Lipid storage disorder, unspecified
0.001 0.515 0.484
E75.5 Other lipid storage disorders
0.001 0.515 0.484
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.515 0.484
E75.3 Sphingolipidosis, unspecified
0.001 0.515 0.484
E75.2 Other sphingolipidosis
0.001 0.515 0.484
E75.1 Other gangliosidosis
0.001 0.515 0.484
E75.0 GM2 gangliosidosis
0.001 0.515 0.484
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.515 0.484
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.515 0.484
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.515 0.484
E76.2 Other mucopolysaccharidoses
0.001 0.515 0.484
E76.1 Mucopolysaccharidosis, type II
0.001 0.515 0.484
E76.0 Mucopolysaccharidosis, type I
0.001 0.515 0.484
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.515 0.484
E77.8 Other disorders of glycoprotein metabolism
0.001 0.515 0.484
E77.1 Defects in glycoprotein degradation
0.001 0.515 0.484
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.515 0.484
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.515 0.484
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.515 0.484
E79.1 Lesch-Nyhan syndrome
0.001 0.515 0.484
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.515 0.484
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.515 0.485
M05 Seropositive rheumatoid arthritis
0.000 0.521 0.479
L44 Other papulosquamous disorders
0.000 0.521 0.479
L41 Parapsoriasis
0.000 0.521 0.479
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.521 0.479
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.522 0.478
E21.3 Hyperparathyroidism, unspecified
0.000 0.523 0.477
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.523 0.477
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.526 0.474
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.526 0.474
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.526 0.474
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.526 0.474
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.526 0.474
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.526 0.474
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.526 0.474
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.472 0.528 0.000
G10 Huntington's disease
0.469 0.531 0.000
G24.4 Idiopathic orofacial dystonia
0.469 0.531 0.000
G24.3 Spasmodic torticollis
0.469 0.531 0.000
G24.2 Idiopathic nonfamilial dystonia
0.469 0.531 0.000
G24.1 Idiopathic familial dystonia
0.469 0.531 0.000
G24.0 Drug-induced dystonia
0.469 0.531 0.000
G30.0 Alzheimer's disease with early onset
0.469 0.531 0.000
G44.3 Chronic posttraumatic headache
0.467 0.533 0.000
G44.1 Vascular headache, not elsewhere classified
0.467 0.533 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.002 0.534 0.464
E22.1 Hyperprolactinaemia
0.000 0.535 0.465
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.535 0.465
E29.1 Testicular hypofunction
0.000 0.536 0.464
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.536 0.464
E22.8 Other hyperfunction of pituitary gland
0.000 0.536 0.464
I15.9 Seconday hypertension, unspecified
0.000 0.536 0.464
I15.8 Other secondary hypertension
0.000 0.536 0.464
I15.2 Hypertension secondary to endocrine disorders
0.000 0.536 0.464
I15.0 Renovascular hypertension
0.000 0.536 0.464
G82.1 Spastic paraplegia
0.463 0.537 0.000
E89.2 Postprocedural hypoparathyroidism
0.001 0.537 0.462
I20.0 Unstable angina
0.000 0.537 0.463
E73.8 Other lactose intolerance
0.001 0.538 0.461
E73.1 Secondary lactase deficiency
0.001 0.538 0.461
E73.0 Congenital lactase deficiency
0.001 0.538 0.461
M75 Shoulder lesions
0.000 0.538 0.462
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.461 0.539 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.458 0.542 0.000
E23.6 Other disorders of pituitary gland
0.000 0.542 0.458
M75.0 Adhesive capsulitis of shoulder
0.000 0.544 0.456
G25.9 Extrapyramidal and movement disorder, unspecified
0.455 0.544 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.545 0.455
E83.5 Disorders of calcium metabolism
0.440 0.545 0.016
G80 Infantile cerebral palsy
0.455 0.545 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.545 0.455
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.454 0.546 0.000
G04.1 Tropical spastic paraplegia
0.454 0.546 0.000
G04.0 Acute disseminated encephalitis
0.454 0.546 0.000
G83.8 Other specified paralytic syndromes
0.453 0.547 0.000
G30.1 Alzheimer's disease with late onset
0.452 0.548 0.000
M70-M79 Other soft tissue disorders
0.000 0.548 0.452
E34 Other endocrine disorders
0.000 0.549 0.451
E88 Other metabolic disorders
0.002 0.550 0.448
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.551 0.449
E23.1 Drug-induced hypopituitarism
0.000 0.551 0.449
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.551 0.449
M75.4 Impingement syndrome of shoulder
0.000 0.552 0.448
E84.8 Cystic fibrosis with other manifestations
0.001 0.552 0.446
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.552 0.446
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.552 0.446
E23.2 Diabetes insipidus
0.000 0.552 0.447
E83.3 Disorders of phosphorus metabolism
0.352 0.554 0.094
G41.0 Grand mal status epilepticus
0.446 0.554 0.000
I00-I02 Acute rheumatic fever
0.000 0.557 0.443
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.558 0.442
G83.9 Paralytic syndrome, unspecified
0.442 0.558 0.000
G41.8 Other status epilepticus
0.442 0.558 0.000
G41.2 Complex partial status epilepticus
0.442 0.558 0.000
G41.1 Petit mal status epilepticus
0.442 0.558 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.438 0.561 0.000
G02.1 Meningitis in mycoses
0.438 0.561 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.438 0.561 0.000
G41.9 Status epilepticus, unspecified
0.438 0.562 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.564 0.436
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.564 0.436
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.565 0.435
L42 Pityriasis rosea
0.000 0.569 0.431
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.431 0.569 0.000
G14 Postpolio syndrome
0.431 0.569 0.000
E73.9 Lactose intolerance, unspecified
0.001 0.569 0.430
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.570 0.430
G00.8 Other bacterial meningitis
0.428 0.572 0.000
G00.3 Staphylococcal meningitis
0.428 0.572 0.000
G00.2 Streptococcal meningitis
0.428 0.572 0.000
G00.0 Haemophilus meningitis
0.428 0.572 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.573 0.427
G70.9 Myoneural disorder, unspecified
0.427 0.573 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.574 0.426
M45 Ankylosing spondylitis
0.000 0.574 0.426
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.425 0.575 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.425 0.575 0.000
G00.1 Pneumococcal meningitis
0.425 0.575 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.575 0.424
E29.8 Other testicular dysfunction
0.000 0.575 0.424
E29.0 Testicular hyperfunction
0.000 0.575 0.424
E22.0 Acromegaly and pituitary gigantism
0.000 0.577 0.422
M45-M49 Spondylopathies
0.000 0.578 0.422
G25.8 Other specified extrapyramidal and movement disorders
0.417 0.583 0.000
G83.1 Monoplegia of lower limb
0.417 0.583 0.000
G00.9 Bacterial meningitis, unspecified
0.416 0.583 0.000
M06.3 Rheumatoid nodule
0.000 0.583 0.417
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.584 0.416
E21.4 Other specified disorders of parathyroid gland
0.000 0.584 0.416
E21.2 Other hyperparathyroidism
0.000 0.584 0.416
G44.4 Drug-induced headache, not elsewhere classified
0.414 0.586 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.586 0.414
G21.9 Secondary Parkinsonism, unspecified
0.413 0.587 0.000
G21.8 Other secondary Parkinsonism
0.413 0.587 0.000
G21.4 Vascular parkinsonism
0.413 0.587 0.000
G21.3 Postencephalitic Parkinsonism
0.413 0.587 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.413 0.587 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.413 0.587 0.000
G21.0 Malignant neuroleptic syndrome
0.413 0.587 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.413 0.587 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.413 0.587 0.000
G23.3 Multiple system atrophy, cerebellar type
0.413 0.587 0.000
G23.2 Striatonigral degeneration
0.413 0.587 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.413 0.587 0.000
G23.0 Hallervorden-Spatz disease
0.413 0.587 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.587 0.413
M06.2 Rheumatoid bursitis
0.000 0.587 0.413
M06.1 Adult-onset Still's disease
0.000 0.587 0.413
G83.5 Locked-in syndrome
0.411 0.589 0.000
G83.3 Monoplegia, unspecified
0.411 0.589 0.000
G83.0 Diplegia of upper limbs
0.411 0.589 0.000
M75.1 Rotator cuff syndrome
0.000 0.590 0.410
L43.3 Subacute (active) lichen planus
0.000 0.591 0.409
L43.2 Lichenoid drug reaction
0.000 0.591 0.409
L43.1 Bullous lichen planus
0.000 0.591 0.409
L43.0 Hypertrophic lichen planus
0.000 0.591 0.409
G11 Hereditary ataxia
0.407 0.593 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.407 0.593 0.000
G25.5 Other chorea
0.407 0.593 0.000
G25.4 Drug-induced chorea
0.407 0.593 0.000
G25.2 Other specified forms of tremor
0.407 0.593 0.000
G25.1 Drug-induced tremor
0.407 0.593 0.000
E61 Deficiency of other nutrient elements
0.000 0.595 0.405
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.595 0.404
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.595 0.404
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.595 0.404
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.595 0.404
E28.9 Ovarian dysfunction, unspecified
0.000 0.596 0.404

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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