TreeWAS – Variant ID: rs3132722

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
E10.9 Without complications	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.001	0.999
L40 Psoriasis	0.000	0.002	0.998
E10.3 With ophthalmic complications	0.000	0.002	0.998
L40.5 Arthropathic psoriasis	0.000	0.002	0.998
K90.0 Coeliac disease	0.000	0.027	0.973
E10.1 With ketoacidosis	0.000	0.043	0.957
L40.0 Psoriasis vulgaris	0.000	0.117	0.883
G35 Multiple sclerosis	0.842	0.158	0.000
E10.0 With coma	0.000	0.188	0.812
E10.2 With renal complications	0.000	0.194	0.806
L40.8 Other psoriasis	0.000	0.236	0.764
L40.4 Guttate psoriasis	0.000	0.284	0.716
L40.2 Acrodermatitis continua	0.000	0.284	0.716
L40.1 Generalised pustular psoriasis	0.000	0.284	0.716
E10.6 With other specified complications	0.000	0.300	0.700
L40.3 Pustulosis palmaris et plantaris	0.000	0.304	0.696
E10.5 With peripheral circulatory complications	0.000	0.326	0.673
E10.7 With multiple complications	0.000	0.328	0.672
E10.4 With neurological complications	0.000	0.360	0.640
E10.8 With unspecified complications	0.000	0.400	0.600
K90 Intestinal malabsorption	0.000	0.418	0.582
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.507	0.492
K90.8 Other intestinal malabsorption	0.000	0.546	0.454
G35-G37 Demyelinating diseases of the central nervous system	0.448	0.552	0.000
E10-E14 Diabetes mellitus	0.001	0.580	0.419
K90.3 Pancreatic steatorrhoea	0.000	0.582	0.417
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.582	0.417
K90.1 Tropical sprue	0.000	0.582	0.417
K90.9 Intestinal malabsorption, unspecified	0.000	0.621	0.379
E13 Other specified diabetes mellitus	0.001	0.648	0.351
G36 Other acute disseminated demyelination	0.347	0.653	0.000
G37 Other demyelinating diseases of central nervous system	0.347	0.653	0.000
E14 Unspecified diabetes mellitus	0.000	0.680	0.320
E13.9 Without complications	0.000	0.697	0.303
E12 Malnutrition-related diabetes mellitus	0.001	0.699	0.300
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.288	0.712	0.000
E83 Disorders of mineral metabolism	0.281	0.719	0.000
E14.3 With ophthalmic complications	0.000	0.723	0.276
G36.0 Neuromyelitis optica [Devic]	0.275	0.725	0.000
E14.4 With neurological complications	0.000	0.743	0.257
E13.8 With unspecified complications	0.001	0.747	0.252
E13.7 With multiple complications	0.001	0.747	0.252
E13.6 With other specified complications	0.001	0.747	0.252
E13.5 With peripheral circulatory complications	0.001	0.747	0.252
E13.4 With neurological complications	0.001	0.747	0.252
E13.3 With ophthalmic complications	0.001	0.747	0.252
E13.2 With renal complications	0.001	0.747	0.252
E13.1 With ketoacidosis	0.001	0.747	0.252
E13.0 With coma	0.001	0.747	0.252
G36.9 Acute disseminated demyelination, unspecified	0.249	0.751	0.000
G36.8 Other specified acute disseminated demyelination	0.249	0.751	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.249	0.751	0.000
E14.5 With peripheral circulatory complications	0.000	0.751	0.249
G37.8 Other specified demyelinating diseases of central nervous system	0.249	0.751	0.000
G37.5 Concentric sclerosis [Balo]	0.249	0.751	0.000
G37.4 Subacute necrotising myelitis	0.249	0.751	0.000
G37.2 Central pontine myelinolysis	0.249	0.751	0.000
G37.1 Central demyelination of corpus callosum	0.249	0.751	0.000
G37.0 Diffuse sclerosis	0.249	0.751	0.000
E14.6 With other specified complications	0.000	0.765	0.235
E14.1 With ketoacidosis	0.000	0.766	0.234
E14.7 With multiple complications	0.000	0.770	0.229
E14.0 With coma	0.000	0.770	0.229
G37.9 Demyelinating disease of central nervous system, unspecified	0.226	0.774	0.000
E83.3 Disorders of phosphorus metabolism	0.224	0.776	0.000
E14.2 Withrenal complications	0.000	0.778	0.222
E14.8 With unspecified complications	0.000	0.780	0.220
E12.9 Without complications	0.001	0.784	0.215
E12.8 With unspecified complications	0.001	0.784	0.215
E12.7 With multiple complications	0.001	0.784	0.215
E12.6 With other specified complications	0.001	0.784	0.215
E12.5 With peripheral circulatory complications	0.001	0.784	0.215
E12.4 With neurological complications	0.001	0.784	0.215
E12.3 With ophthalmic complications	0.001	0.784	0.215
E12.2 With renal complications	0.001	0.784	0.215
E12.1 With ketoacidosis	0.001	0.784	0.215
E12.0 With coma	0.001	0.784	0.215
E83.9 Disorder of mineral metabolism, unspecified	0.202	0.798	0.000
E83.8 Other disorders of mineral metabolism	0.202	0.798	0.000
E83.2 Disorders of zinc metabolism	0.202	0.798	0.000
E83.0 Disorders of copper metabolism	0.202	0.798	0.000
L40-L45 Papulosquamous disorders	0.001	0.801	0.198
E11 Non-insulin-dependent diabetes mellitus	0.000	0.846	0.154
L44 Other papulosquamous disorders	0.001	0.857	0.142
L41 Parapsoriasis	0.001	0.857	0.142
L45 Papulosquamous disorders in diseases classified elsewhere	0.001	0.857	0.142
E11.6 With other specified complications	0.000	0.866	0.134
E11.1 With ketoacidosis	0.000	0.868	0.132
L42 Pityriasis rosea	0.001	0.869	0.130
E83.4 Disorders of magnesium metabolism	0.129	0.871	0.000
E11.0 With coma	0.000	0.873	0.127
E83.5 Disorders of calcium metabolism	0.125	0.875	0.000
E11.2 With renal complications	0.000	0.879	0.121
E11.7 With multiple complications	0.000	0.889	0.111
E11.5 With peripheral circulatory complications	0.000	0.897	0.103
L41.9 Parapsoriasis, unspecified	0.001	0.897	0.102
L41.8 Other parapsoriasis	0.001	0.897	0.102
L41.5 Retiform parapsoriasis	0.001	0.897	0.102
L41.4 Large plaque parapsoriasis	0.001	0.897	0.102
L41.3 Small plaque parapsoriasis	0.001	0.897	0.102
L41.2 Lymphomatoid papulosis	0.001	0.897	0.102
L41.1 Pityriasis lichenoides chronica	0.001	0.897	0.102
L41.0 Pityriasis lichenoides et varioliformis acuta	0.001	0.897	0.102
L44.9 Papulosquamous disorder, unspecified	0.001	0.897	0.102
L44.8 Other specified papulosquamous disorders	0.001	0.897	0.102
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.001	0.897	0.102
L44.3 Lichen ruber moniliformis	0.001	0.897	0.102
L44.2 Lichen striatus	0.001	0.897	0.102
L44.1 Lichen nitidus	0.001	0.897	0.102
L44.0 Pityriasis rubra pilaris	0.001	0.897	0.102
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.095	0.905	0.000
E11.8 With unspecified complications	0.000	0.906	0.094
E70-E90 Metabolic disorders	0.091	0.909	0.000
E89.0 Postprocedural hypothyroidism	0.091	0.909	0.000
E89.2 Postprocedural hypoparathyroidism	0.088	0.912	0.000
E89.1 Postprocedural hypoinsulinaemia	0.078	0.922	0.000
E89.4 Postprocedural ovarian failure	0.077	0.923	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.073	0.927	0.000
E79 Disorders of purine and pyrimidine metabolism	0.070	0.930	0.000
E84 Cystic fibrosis	0.069	0.931	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.068	0.932	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.068	0.932	0.000
E89.5 Postprocedural testicular hypofunction	0.068	0.932	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.066	0.934	0.000
E74 Other disorders of carbohydrate metabolism	0.066	0.934	0.000
L43 Lichen planus	0.002	0.934	0.063
E14.9 Without complications	0.000	0.934	0.066
E77 Disorders of glycoprotein metabolism	0.066	0.934	0.000
E76 Disorders of glycosaminoglycan metabolism	0.066	0.934	0.000
E72 Other disorders of amino-acid metabolism	0.066	0.934	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.066	0.934	0.000
E70 Disorders of aromatic amino-acid metabolism	0.066	0.934	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.066	0.934	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.063	0.937	0.000
E73 Lactose intolerance	0.062	0.938	0.000
E11.4 With neurological complications	0.000	0.938	0.062
E85 Amyloidosis	0.059	0.940	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.054	0.945	0.000
E84.9 Cystic fibrosis, unspecified	0.053	0.947	0.000
E80.1 Porphyria cutanea tarda	0.052	0.948	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.050	0.950	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.050	0.950	0.000
E79.1 Lesch-Nyhan syndrome	0.050	0.950	0.000
E84.8 Cystic fibrosis with other manifestations	0.050	0.950	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.050	0.950	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.050	0.950	0.000
E80.6 Other disorders of bilirubin metabolism	0.048	0.951	0.000
K90-K93 Other diseases of the digestive system	0.000	0.952	0.048
E75.5 Other lipid storage disorders	0.048	0.952	0.000
E85.3 Secondary systemic amyloidosis	0.048	0.952	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.048	0.952	0.000
E75.6 Lipid storage disorder, unspecified	0.047	0.952	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.047	0.952	0.000
E75.3 Sphingolipidosis, unspecified	0.047	0.952	0.000
E75.2 Other sphingolipidosis	0.047	0.952	0.000
E75.1 Other gangliosidosis	0.047	0.952	0.000
E75.0 GM2 gangliosidosis	0.047	0.952	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.047	0.952	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.047	0.952	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.047	0.952	0.000
E74.2 Disorders of galactose metabolism	0.047	0.952	0.000
E74.1 Disorders of fructose metabolism	0.047	0.952	0.000
E74.0 Glycogen storage disease	0.047	0.952	0.000
L43.3 Subacute (active) lichen planus	0.002	0.953	0.046
L43.2 Lichenoid drug reaction	0.002	0.953	0.046
L43.1 Bullous lichen planus	0.002	0.953	0.046
L43.0 Hypertrophic lichen planus	0.002	0.953	0.046
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.047	0.953	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.047	0.953	0.000
E70.3 Albinism	0.047	0.953	0.000
E70.2 Disorders of tyrosine metabolism	0.047	0.953	0.000
E70.1 Other hyperphenylalaninaemias	0.047	0.953	0.000
E70.0 Classical phenylketonuria	0.047	0.953	0.000
E71.3 Disorders of fatty-acid metabolism	0.047	0.953	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.047	0.953	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.047	0.953	0.000
E71.0 Maple-syrup-urine disease	0.047	0.953	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.047	0.953	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.047	0.953	0.000
E72.5 Disorders of glycine metabolism	0.047	0.953	0.000
E72.4 Disorders of ornithine metabolism	0.047	0.953	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.047	0.953	0.000
E72.2 Disorders of urea cycle metabolism	0.047	0.953	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.047	0.953	0.000
E72.0 Disorders of amino-acid transport	0.047	0.953	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.047	0.953	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.047	0.953	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.047	0.953	0.000
E76.2 Other mucopolysaccharidoses	0.047	0.953	0.000
E76.1 Mucopolysaccharidosis, type II	0.047	0.953	0.000
E76.0 Mucopolysaccharidosis, type I	0.047	0.953	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.047	0.953	0.000
E77.8 Other disorders of glycoprotein metabolism	0.047	0.953	0.000
E77.1 Defects in glycoprotein degradation	0.047	0.953	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.047	0.953	0.000
E88 Other metabolic disorders	0.047	0.953	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.033	0.953	0.013
E80.7 Disorder of bilirubin metabolism, unspecified	0.045	0.954	0.000
E80.5 Crigler-Najjar syndrome	0.045	0.954	0.000
E80.3 Defects of catalase and peroxydase	0.045	0.954	0.000
E80.0 Hereditary erythropoietic porphyria	0.045	0.954	0.000
E73.8 Other lactose intolerance	0.045	0.955	0.000
E73.1 Secondary lactase deficiency	0.045	0.955	0.000
E73.0 Congenital lactase deficiency	0.045	0.955	0.000
E89.3 Postprocedural hypopituitarism	0.044	0.956	0.000
E85.8 Other amyloidosis	0.043	0.957	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.043	0.957	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.043	0.957	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.043	0.957	0.000
E73.9 Lactose intolerance, unspecified	0.041	0.958	0.000
E80.2 Other porphyria	0.039	0.961	0.000
E85.9 Amyloidosis, unspecified	0.039	0.961	0.000
L43.8 Other lichen planus	0.002	0.964	0.034
E80.4 Gilbert's syndrome	0.036	0.964	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.036	0.964	0.000
E88.9 Metabolic disorder, unspecified	0.035	0.965	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.965	0.035
E88.8 Other specified metabolic disorders	0.034	0.966	0.000
E40-E46 Malnutrition	0.027	0.966	0.007
E88.3 Tumour lysis syndrome	0.034	0.966	0.000
I20.8 Other forms of angina pectoris	0.034	0.966	0.000
E85.4 Organ-limited amyloidosis	0.033	0.967	0.000
E65-E68 Obesity and other hyperalimentation	0.029	0.968	0.003
E06.3 Autoimmune thyroiditis	0.032	0.968	0.000
E06 Thyroiditis	0.031	0.969	0.000
E00-E07 Disorders of thyroid gland	0.030	0.969	0.001
E50-E64 Other nutritional deficiencies	0.021	0.970	0.009
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.016	0.970	0.014
E65 Localised adiposity	0.029	0.970	0.001
E03 Other hypothyroidism	0.028	0.972	0.001
E03.9 Hypothyroidism, unspecified	0.028	0.972	0.000
E88.2 Lipomatosis, not elsewhere classified	0.026	0.974	0.000
E46 Unspecified protein-energy malnutrition	0.023	0.974	0.002
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.975	0.025
K93.1 Megacolon in Chagas' disease	0.000	0.975	0.025
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.975	0.025
E06.9 Thyroiditis, unspecified	0.025	0.975	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.020	0.975	0.005
E45 Retarded development following protein-energy malnutrition	0.020	0.975	0.005
E43 Unspecified severe protein-energy malnutrition	0.020	0.975	0.005
E42 Marasmic kwashiorkor	0.020	0.975	0.005
E41 Nutritional marasmus	0.020	0.975	0.005
E40 Kwashiorkor	0.020	0.975	0.005
E67 Other hyperalimentation	0.021	0.977	0.002
E68 Sequelae of hyperalimentation	0.021	0.977	0.002
E06.5 Other chronic thyroiditis	0.023	0.977	0.000
E06.4 Drug-induced thyroiditis	0.022	0.977	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.022	0.977	0.000
E06.1 Subacute thyroiditis	0.022	0.977	0.000
E06.0 Acute thyroiditis	0.022	0.977	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.022	0.977	0.001
E00 Congenital iodine-deficiency syndrome	0.022	0.977	0.001
E02 Subclinical iodine-deficiency hypothyroidism	0.021	0.978	0.001
E64 Sequelae of malnutrition and other nutritional deficiencies	0.015	0.978	0.007
E63 Other nutritional deficiencies	0.015	0.978	0.007
E50 Vitamin A deficiency	0.015	0.978	0.007
E60 Dietary zinc deficiency	0.015	0.978	0.007
E59 Dietary selenium deficiency	0.015	0.978	0.007
E54 Ascorbic acid deficiency	0.015	0.978	0.007
E52 Niacin deficiency [pellagra]	0.015	0.978	0.007
E56 Other vitamin deficiencies	0.015	0.978	0.007
E53 Deficiency of other B group vitamins	0.019	0.978	0.003
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.022	0.978	0.000
E51 Thiamine deficiency	0.015	0.978	0.007
E15 Nondiabetic hypoglycaemic coma	0.012	0.978	0.010
E58 Dietary calcium deficiency	0.015	0.979	0.007
E86 Volume depletion	0.021	0.979	0.000
E03.5 Myxoedema coma	0.020	0.980	0.001
E03.4 Atrophy of thyroid (acquired)	0.020	0.980	0.001
E03.3 Postinfectious hypothyroidism	0.020	0.980	0.001
E03.1 Congenital hypothyroidism without goitre	0.020	0.980	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.020	0.980	0.001
C73 Malignant neoplasm of thyroid gland	0.020	0.980	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.018	0.981	0.001
S02.20 Fracture of nasal bones (closed)	0.000	0.981	0.019
E04 Other non-toxic goitre	0.018	0.981	0.000
E16 Other disorders of pancreatic internal secretion	0.003	0.982	0.015
E44.1 Mild protein-energy malnutrition	0.014	0.982	0.004
E44.0 Moderate protein-energy malnutrition	0.014	0.982	0.004
E61 Deficiency of other nutrient elements	0.009	0.982	0.009
R52.1 Chronic intractable pain	0.017	0.983	0.000
E67.8 Other specified hyperalimentation	0.015	0.983	0.002
E67.3 Hypervitaminosis D	0.015	0.983	0.002
E67.2 Megavitamin-B6 syndrome	0.015	0.983	0.002
E67.1 Hypercarotenaemia	0.015	0.983	0.002
E67.0 Hypervitaminosis A	0.015	0.983	0.002
E55 Vitamin D deficiency	0.011	0.983	0.006
E53.9 Vitamin B deficiency, unspecified	0.015	0.983	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.016	0.983	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.016	0.983	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.016	0.983	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.016	0.983	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.016	0.983	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.016	0.983	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.016	0.983	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.016	0.983	0.001
E53.8 Deficiency of other specified B group vitamins	0.016	0.983	0.000
E03.8 Other specified hypothyroidism	0.016	0.984	0.001
E20-E35 Disorders of other endocrine glands	0.013	0.984	0.003
E50.9 Vitamin A deficiency, unspecified	0.011	0.984	0.005
E50.8 Other manifestations of vitamin A deficiency	0.011	0.984	0.005
E50.7 Other ocular manifestations of vitamin A deficiency	0.011	0.984	0.005
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.011	0.984	0.005
E50.5 Vitamin A deficiency with night blindness	0.011	0.984	0.005
E50.4 Vitamin A deficiency with keratomalacia	0.011	0.984	0.005
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.011	0.984	0.005
E50.2 Vitamin A deficiency with corneal xerosis	0.011	0.984	0.005
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.011	0.984	0.005
E50.0 Vitamin A deficiency with conjunctival xerosis	0.011	0.984	0.005
E63.9 Nutritional deficiency, unspecified	0.011	0.984	0.005
E63.8 Other specified nutritional deficiencies	0.011	0.984	0.005
E63.1 Imbalance of constituents of food intake	0.011	0.984	0.005
E63.0 Essential fatty acid [EFA] deficiency	0.011	0.984	0.005
E64.9 Sequelae of unspecified nutritional deficiency	0.011	0.984	0.005
E64.8 Sequelae of other nutritional deficiencies	0.011	0.984	0.005
E64.3 Sequelae of rickets	0.011	0.984	0.005
E64.2 Sequelae of vitamin C deficiency	0.011	0.984	0.005
E64.1 Sequelae of vitamin A deficiency	0.011	0.984	0.005
E64.0 Sequelae of protein-energy malnutrition	0.011	0.984	0.005
E56.9 Vitamin deficiency, unspecified	0.011	0.984	0.005
E56.8 Deficiency of other vitamins	0.011	0.984	0.005
E56.0 Deficiency of vitamin E	0.011	0.984	0.005
E04.2 Non-toxic multinodular goitre	0.016	0.984	0.000
E53.1 Pyridoxine deficiency	0.013	0.984	0.002
E53.0 Riboflavin deficiency	0.013	0.984	0.002
E51.9 Thiamine deficiency, unspecified	0.011	0.984	0.005
E51.8 Other manifestations of thiamine deficiency	0.011	0.984	0.005
E51.1 Beriberi	0.011	0.984	0.005
E56.1 Deficiency of vitamin K	0.011	0.984	0.005
E51.2 Wernicke's encephalopathy	0.011	0.984	0.005
E11.3 With ophthalmic complications	0.000	0.985	0.015
E16.0 Drug-induced hypoglycaemia without coma	0.001	0.985	0.014
R52 Pain, not elsewhere classified	0.015	0.985	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.985	0.015
R52.2 Other chronic pain	0.015	0.985	0.000
E16.1 Other hypoglycaemia	0.002	0.986	0.012
E04.0 Non-toxic diffuse goitre	0.014	0.986	0.000
R52.0 Acute pain	0.014	0.986	0.000
E04.8 Other specified non-toxic goitre	0.013	0.986	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.987	0.013
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.987	0.011
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.987	0.011
E16.4 Abnormal secretion of gastrin	0.002	0.987	0.011
E16.3 Increased secretion of glucagon	0.002	0.987	0.011
E61.9 Deficiency of nutrient element, unspecified	0.006	0.987	0.007
E61.8 Deficiency of other specified nutrient elements	0.006	0.987	0.007
E61.7 Deficiency of multiple nutrient elements	0.006	0.987	0.007
E61.6 Vanadium deficiency	0.006	0.987	0.007
E61.5 Molybdenum deficiency	0.006	0.987	0.007
E61.4 Chromium deficiency	0.006	0.987	0.007
E61.3 Manganese deficiency	0.006	0.987	0.007
E61.0 Copper deficiency	0.006	0.987	0.007
E26 Hyperaldosteronism	0.012	0.987	0.002
E04.9 Non-toxic goitre, unspecified	0.013	0.987	0.000
E61.2 Magnesium deficiency	0.006	0.987	0.007
K91.3 Postoperative intestinal obstruction	0.000	0.987	0.013
E55.0 Rickets, active	0.008	0.988	0.004
E34 Other endocrine disorders	0.011	0.988	0.002
E25 Adrenogenital disorders	0.010	0.988	0.002
E27 Other disorders of adrenal gland	0.012	0.988	0.000
E07 Other disorders of thyroid	0.011	0.988	0.001
E35 Disorders of endocrine glands in diseases classified elsewhere	0.010	0.988	0.002
E32 Diseases of thymus	0.010	0.988	0.002
E31 Polyglandular dysfunction	0.010	0.988	0.002
E30 Disorders of puberty, not elsewhere classified	0.010	0.988	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.988	0.012
E29 Testicular dysfunction	0.010	0.988	0.002
E20 Hypoparathyroidism	0.010	0.988	0.002
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.011	0.989	0.000
C18.7 Sigmoid colon	0.000	0.989	0.011
E61.1 Iron deficiency	0.002	0.989	0.009
E66 Obesity	0.011	0.989	0.000
I38 Endocarditis, valve unspecified	0.011	0.989	0.000
E26.0 Primary hyperaldosteronism	0.010	0.989	0.001
M79.60 Pain in limb (Multiple sites)	0.000	0.989	0.011
H52.2 Astigmatism	0.010	0.990	0.000
E27.2 Addisonian crisis	0.010	0.990	0.000
E27.1 Primary adrenocortical insufficiency	0.010	0.990	0.000
C18.9 Colon, unspecified	0.000	0.990	0.010
E26.9 Hyperaldosteronism, unspecified	0.009	0.990	0.001
R52.9 Pain, unspecified	0.010	0.990	0.000
E34.9 Endocrine disorder, unspecified	0.009	0.990	0.001
E34.0 Carcinoid syndrome	0.009	0.990	0.001
E28 Ovarian dysfunction	0.007	0.990	0.002
E26.8 Other hyperaldosteronism	0.008	0.990	0.001
E26.1 Secondary hyperaldosteronism	0.008	0.990	0.001
E27.3 Drug-induced adrenocortical insufficiency	0.009	0.990	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.008	0.990	0.001
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.009	0.991	0.000
E34.5 Androgen resistance syndrome	0.008	0.991	0.001
E34.4 Constitutional tall stature	0.008	0.991	0.001
E34.3 Short stature, not elsewhere classified	0.008	0.991	0.001
E34.2 Ectopic hormone secretion, not elsewhere classified	0.008	0.991	0.001
E34.1 Other hypersecretion of intestinal hormones	0.008	0.991	0.001
E25.9 Adrenogenital disorder, unspecified	0.008	0.991	0.002
E25.8 Other adrenogenital disorders	0.008	0.991	0.002
E66.2 Extreme obesity with alveolar hypoventilation	0.009	0.991	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.991	0.009
E27.5 Adrenomedullary hyperfunction	0.008	0.991	0.000
E27.0 Other adrenocortical overactivity	0.008	0.991	0.000
E07.1 Dyshormogenetic goitre	0.008	0.991	0.001
E07.0 Hypersecretion of calcitonin	0.008	0.991	0.001
E30.9 Disorder of puberty, unspecified	0.007	0.991	0.002
E30.8 Other disorders of puberty	0.007	0.991	0.002
E30.1 Precocious puberty	0.007	0.991	0.002
E30.0 Delayed puberty	0.007	0.991	0.002
E31.9 Polyglandular dysfunction, unspecified	0.007	0.991	0.002
E31.8 Other polyglandular dysfunction	0.007	0.991	0.002
E31.1 Polyglandular hyperfunction	0.007	0.991	0.002
E31.0 Autoimmune polyglandular failure	0.007	0.991	0.002
E32.9 Disease of thymus, unspecified	0.007	0.991	0.002
E32.8 Other diseases of thymus	0.007	0.991	0.002
E32.1 Abscess of thymus	0.007	0.991	0.002
E32.0 Persistent hyperplasia of thymus	0.007	0.991	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.007	0.991	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.007	0.991	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.007	0.991	0.002
E24 Cushing's syndrome	0.006	0.991	0.003
E23 Hypofunction and other disorders of pituitary gland	0.007	0.991	0.002
E29.9 Testicular dysfunction, unspecified	0.007	0.991	0.001
E29.8 Other testicular dysfunction	0.007	0.991	0.001
E29.0 Testicular hyperfunction	0.007	0.991	0.001
E20.8 Other hypoparathyroidism	0.007	0.991	0.002
E20.1 Pseudohypoparathyroidism	0.007	0.991	0.002
E20.0 Idiopathic hypoparathyroidism	0.007	0.991	0.002
E27.8 Other specified disorders of adrenal gland	0.008	0.992	0.000
C18 Malignant neoplasm of colon	0.000	0.992	0.008
I71 Aortic aneurysm and dissection	0.008	0.992	0.000
C18.2 Ascending colon	0.000	0.992	0.008
E29.1 Testicular hypofunction	0.008	0.992	0.001
E66.0 Obesity due to excess calories	0.008	0.992	0.000
E20.9 Hypoparathyroidism, unspecified	0.007	0.992	0.001
E22 Hyperfunction of pituitary gland	0.006	0.992	0.002
E66.1 Drug-induced obesity	0.008	0.992	0.000
S02.2 Fracture of nasal bones	0.000	0.992	0.008
K92 Other diseases of digestive system	0.000	0.992	0.008
L43.9 Lichen planus, unspecified	0.003	0.992	0.004
G99.2 Myelopathy in diseases classified elsewhere	0.008	0.992	0.000
I71.0 Dissection of aorta [any part]	0.008	0.992	0.000
C18.1 Appendix	0.000	0.992	0.008
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.992	0.007
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.005	0.993	0.002
C74 Malignant neoplasm of adrenal gland	0.007	0.993	0.000
E55.9 Vitamin D deficiency, unspecified	0.004	0.993	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.007	0.993	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.993	0.007
I71.3 Abdominal aortic aneurysm, ruptured	0.007	0.993	0.000
E34.8 Other specified endocrine disorders	0.006	0.993	0.002
E28.3 Primary ovarian failure	0.006	0.993	0.001
E28.9 Ovarian dysfunction, unspecified	0.005	0.993	0.002
E28.8 Other ovarian dysfunction	0.005	0.993	0.002
E28.1 Androgen excess	0.005	0.993	0.002
E28.0 Oestrogen excess	0.005	0.993	0.002
E27.9 Disorder of adrenal gland, unspecified	0.007	0.993	0.001
K91.1 Postgastric surgery syndromes	0.000	0.993	0.007
K92.8 Other specified diseases of digestive system	0.000	0.993	0.007
E23.6 Other disorders of pituitary gland	0.006	0.993	0.001
C18.6 Descending colon	0.000	0.993	0.007
E24.8 Other Cushing's syndrome	0.004	0.993	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.993	0.002
E24.3 Ectopic ACTH syndrome	0.004	0.993	0.002
E24.1 Nelson's syndrome	0.004	0.993	0.002
E24.0 Pituitary-dependent Cushing's disease	0.004	0.993	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.993	0.001
E23.1 Drug-induced hypopituitarism	0.005	0.993	0.001
C75 Malignant neoplasm of other endocrine glands and related structures	0.006	0.994	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.006	0.994	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.994	0.001
N13 Obstructive and reflux uropathy	0.000	0.994	0.006
E07.8 Other specified disorders of thyroid	0.005	0.994	0.001
I71.8 Aortic aneurysm of unspecified site, ruptured	0.006	0.994	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.006	0.994	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.006	0.994	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.994	0.006
E22.9 Hyperfunction of pituitary gland, unspecified	0.005	0.994	0.002
E22.8 Other hyperfunction of pituitary gland	0.005	0.994	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.994	0.006
C74.0 Cortex of adrenal gland	0.006	0.994	0.000
C18.8 Overlapping lesion of colon	0.000	0.994	0.006
E05 Thyrotoxicosis [hyperthyroidism]	0.005	0.994	0.000
K92.1 Melaena	0.000	0.994	0.006
S02.21 Fracture of nasal bones (open)	0.000	0.994	0.006
E22.0 Acromegaly and pituitary gigantism	0.005	0.994	0.001
E24.2 Drug-induced Cushing's syndrome	0.003	0.994	0.003
C74.9 Adrenal gland, unspecified	0.006	0.994	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.001	0.994	0.005
Q61 Cystic kidney disease	0.000	0.994	0.006
E21.2 Other hyperparathyroidism	0.004	0.994	0.002
C74.1 Medulla of adrenal gland	0.005	0.994	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.994	0.002
E21.4 Other specified disorders of parathyroid gland	0.004	0.994	0.002
Q61.2 Polycystic kidney, adult type	0.000	0.994	0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.006	0.994	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.004	0.995	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.005	0.995	0.000
E24.9 Cushing's syndrome, unspecified	0.002	0.995	0.003
E23.0 Hypopituitarism	0.005	0.995	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations