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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132944
log Bayes Factor = 208.472
Chromosome 6   position 32,307,446  (GRCh37) Explore rs3132944 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
M35 Other systemic involvement of connective tissue
0.000 0.002 0.998
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
E11.3 With ophthalmic complications
0.000 0.002 0.998
I10-I15 Hypertensive diseases
0.000 0.002 0.998
E14.3 With ophthalmic complications
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
I10 Essential (primary) hypertension
0.000 0.003 0.997
G37 Other demyelinating diseases of central nervous system
0.997 0.003 0.000
M20-M25 Other joint disorders
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.000 0.004 0.996
L40.9 Psoriasis, unspecified
0.000 0.006 0.994
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
M07 Psoriatic and enteropathic arthropathies
0.000 0.007 0.993
J33.8 Other polyp of sinus
0.000 0.008 0.992
E10.5 With peripheral circulatory complications
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.012 0.988
M07.3 Other psoriatic arthropathies
0.000 0.012 0.988
I20-I25 Ischaemic heart diseases
0.000 0.013 0.987
I22 Subsequent myocardial infarction
0.000 0.013 0.987
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.015 0.985
L43 Lichen planus
0.000 0.016 0.984
H40-H42 Glaucoma
0.000 0.023 0.977
I12 Hypertensive renal disease
0.000 0.025 0.975
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.027 0.973
E06 Thyroiditis
0.000 0.028 0.972
E10.2 With renal complications
0.000 0.031 0.969
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.031 0.969
H34 Retinal vascular occlusions
0.000 0.036 0.964
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.038 0.962
H40 Glaucoma
0.000 0.038 0.962
L43.9 Lichen planus, unspecified
0.000 0.039 0.961
M06.0 Seronegative rheumatoid arthritis
0.000 0.039 0.961
H40.9 Glaucoma, unspecified
0.000 0.040 0.960
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.043 0.957
I12.9 Hypertensive renal disease without renal failure
0.000 0.043 0.957
M06.3 Rheumatoid nodule
0.000 0.044 0.956
E06.3 Autoimmune thyroiditis
0.000 0.045 0.955
M34 Systemic sclerosis
0.000 0.049 0.951
E10.8 With unspecified complications
0.000 0.051 0.949
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.063 0.937
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.070 0.930
E10.0 With coma
0.000 0.071 0.929
M65-M68 Disorders of synovium and tendon
0.000 0.081 0.919
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.088 0.912
M45-M49 Spondylopathies
0.000 0.088 0.912
M45 Ankylosing spondylitis
0.000 0.090 0.910
M06.4 Inflammatory polyarthropathy
0.000 0.098 0.902
E78.2 Mixed hyperlipidaemia
0.000 0.103 0.897
M65 Synovitis and tenosynovitis
0.000 0.103 0.897
E88 Other metabolic disorders
0.000 0.105 0.895
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.111 0.889
E78.1 Pure hyperglyceridaemia
0.000 0.118 0.882
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.118 0.882
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.119 0.881
E07 Other disorders of thyroid
0.000 0.119 0.881
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.119 0.881
M35.1 Other overlap syndromes
0.000 0.126 0.874
H34.8 Other retinal vascular occlusions
0.000 0.128 0.872
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.129 0.871
M06.34 Rheumatoid nodule (Hand)
0.000 0.133 0.867
M34.1 CR(E)ST syndrome
0.000 0.135 0.865
G37.8 Other specified demyelinating diseases of central nervous system
0.864 0.136 0.000
H34.2 Other retinal artery occlusions
0.000 0.139 0.861
E11.2 With renal complications
0.000 0.145 0.855
L43.8 Other lichen planus
0.000 0.147 0.853
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.150 0.850
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.151 0.849
E10.6 With other specified complications
0.000 0.151 0.848
M35.7 Hypermobility syndrome
0.000 0.153 0.847
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.155 0.845
M34.9 Systemic sclerosis, unspecified
0.000 0.155 0.845
E11.5 With peripheral circulatory complications
0.000 0.156 0.844
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.157 0.843
E83 Disorders of mineral metabolism
0.581 0.159 0.260
H35 Other retinal disorders
0.000 0.161 0.839
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.162 0.838
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.166 0.834
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.166 0.834
L40.8 Other psoriasis
0.000 0.167 0.833
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.169 0.831
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.171 0.829
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.172 0.828
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.175 0.825
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.175 0.825
I21 Acute myocardial infarction
0.000 0.185 0.815
E14.4 With neurological complications
0.000 0.187 0.813
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.189 0.811
E03.8 Other specified hypothyroidism
0.000 0.189 0.810
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.192 0.808
I15 Secondary hypertension
0.000 0.198 0.801
L57.0 Actinic keratosis
0.000 0.203 0.797
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.205 0.795
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.207 0.793
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.207 0.793
H35.4 Peripheral retinal degeneration
0.000 0.207 0.793
E89.0 Postprocedural hypothyroidism
0.000 0.208 0.792
M86-M90 Other osteopathies
0.000 0.208 0.792
M31 Other necrotising vasculopathies
0.000 0.210 0.790
M30 Polyarteritis nodosa and related conditions
0.000 0.210 0.790
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.212 0.788
E11.8 With unspecified complications
0.000 0.215 0.785
H35.8 Other specified retinal disorders
0.000 0.216 0.784
L80 Vitiligo
0.000 0.219 0.781
E14.5 With peripheral circulatory complications
0.000 0.222 0.778
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.222 0.778
I11 Hypertensive heart disease
0.000 0.225 0.775
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.227 0.773
E07.9 Disorder of thyroid, unspecified
0.000 0.228 0.772
H40.4 Glaucoma secondary to eye inflammation
0.000 0.229 0.771
E74 Other disorders of carbohydrate metabolism
0.000 0.229 0.771
D64.9 Anaemia, unspecified
0.000 0.230 0.770
I21.9 Acute myocardial infarction, unspecified
0.000 0.230 0.770
D60-D64 Aplastic and other anaemias
0.000 0.230 0.770
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.231 0.769
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.233 0.767
D64 Other anaemias
0.000 0.233 0.767
M35.2 Behcet's disease
0.000 0.237 0.763
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.761 0.239 0.000
M86 Osteomyelitis
0.000 0.241 0.759
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.245 0.755
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.247 0.753
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.252 0.748
H40.5 Glaucoma secondary to other eye disorders
0.000 0.260 0.740
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.262 0.738
M86.9 Osteomyelitis, unspecified
0.000 0.263 0.737
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.265 0.735
H34.9 Retinal vascular occlusion, unspecified
0.000 0.265 0.734
H34.1 Central retinal artery occlusion
0.000 0.269 0.731
L40.3 Pustulosis palmaris et plantaris
0.000 0.269 0.731
G36 Other acute disseminated demyelination
0.730 0.269 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.270 0.730
E14.2 Withrenal complications
0.000 0.271 0.729
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.272 0.728
H33 Retinal detachments and breaks
0.000 0.273 0.727
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.275 0.725
E16.1 Other hypoglycaemia
0.000 0.277 0.723
I12.0 Hypertensive renal disease with renal failure
0.000 0.277 0.723
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.279 0.721
M91-M94 Chondropathies
0.000 0.279 0.721
E40-E46 Malnutrition
0.000 0.281 0.719
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.281 0.719
H40.1 Primary open-angle glaucoma
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.284 0.716
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.284 0.716
M35.5 Multifocal fibrosclerosis
0.000 0.284 0.716
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.284 0.716
Chapter VIII Diseases of the ear and mastoid process
0.000 0.285 0.715
I13 Hypertensive heart and renal disease
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.286 0.714
H43-H45 Disorders of vitreous body and globe
0.000 0.286 0.714
I00-I02 Acute rheumatic fever
0.000 0.286 0.714
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.286 0.714
E88.8 Other specified metabolic disorders
0.000 0.288 0.712
M07.5 Arthropathy in ulcerative colitis
0.000 0.288 0.712
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.288 0.712
M07.2 Psoriatic spondylitis
0.000 0.288 0.712
M07.1 Arthritis mutilans
0.000 0.288 0.712
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.288 0.712
E88.2 Lipomatosis, not elsewhere classified
0.000 0.288 0.712
M07.38 Other psoriatic arthropathies (Other)
0.000 0.291 0.709
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.291 0.709
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.291 0.709
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.291 0.709
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.291 0.709
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.291 0.709
L85 Other epidermal thickening
0.000 0.292 0.708
M14 Arthropathies in other diseases classified elsewhere
0.000 0.293 0.707
L43.3 Subacute (active) lichen planus
0.000 0.294 0.706
L43.2 Lichenoid drug reaction
0.000 0.294 0.706
L43.1 Bullous lichen planus
0.000 0.294 0.706
L43.0 Hypertrophic lichen planus
0.000 0.294 0.706
E13 Other specified diabetes mellitus
0.000 0.296 0.704
E78.4 Other hyperlipidaemia
0.000 0.297 0.703
H42 Glaucoma in diseases classified elsewhere
0.000 0.299 0.700
E70 Disorders of aromatic amino-acid metabolism
0.000 0.300 0.700
H30 Chorioretinal inflammation
0.000 0.301 0.699
E06.5 Other chronic thyroiditis
0.000 0.303 0.697
E06.4 Drug-induced thyroiditis
0.000 0.303 0.697
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.303 0.697
E06.1 Subacute thyroiditis
0.000 0.303 0.697
E06.0 Acute thyroiditis
0.000 0.303 0.697
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.304 0.696
M34.8 Other forms of systemic sclerosis
0.000 0.306 0.694
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.307 0.693
H34.0 Transient retinal artery occlusion
0.000 0.309 0.691
E79 Disorders of purine and pyrimidine metabolism
0.000 0.309 0.691
H35.6 Retinal haemorrhage
0.000 0.309 0.691
H40.6 Glaucoma secondary to drugs
0.000 0.310 0.689
H40.3 Glaucoma secondary to eye trauma
0.000 0.310 0.689
L10-L14 Bullous disorders
0.000 0.311 0.689
E11.6 With other specified complications
0.000 0.311 0.689
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.311 0.689
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.311 0.689
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.311 0.689
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.311 0.689
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.311 0.689
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.311 0.689
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.311 0.689
H60-H62 Diseases of external ear
0.000 0.313 0.687
E07.8 Other specified disorders of thyroid
0.000 0.313 0.687
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.315 0.685
M06.38 Rheumatoid nodule (Other)
0.000 0.315 0.685
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.315 0.685
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.315 0.685
M06.33 Rheumatoid nodule (Forearm)
0.000 0.315 0.685
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.315 0.685
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.315 0.685
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.318 0.682
M34.0 Progressive systemic sclerosis
0.000 0.318 0.682
H35.7 Separation of retinal layers
0.000 0.325 0.675
H33.3 Retinal breaks without detachment
0.000 0.327 0.673
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.331 0.669
M12 Other specific arthropathies
0.000 0.333 0.667
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.333 0.667
I24 Other acute ischaemic heart diseases
0.000 0.334 0.666
E84 Cystic fibrosis
0.000 0.334 0.666
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.334 0.665
M07.6 Other enteropathic arthropathies
0.000 0.336 0.664
M65.1 Other infective (teno)synovitis
0.000 0.340 0.660
M31.6 Other giant cell arteritis
0.000 0.341 0.659
M49 Spondylopathies in diseases classified elsewhere
0.000 0.341 0.659
E72 Other disorders of amino-acid metabolism
0.000 0.341 0.659
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.341 0.659
L94 Other localised connective tissue disorders
0.000 0.343 0.657
E65-E68 Obesity and other hyperalimentation
0.000 0.343 0.657
L40.0 Psoriasis vulgaris
0.000 0.343 0.657
M31.3 Wegener's granulomatosis
0.000 0.347 0.653
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.348 0.652
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.348 0.652
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.348 0.652
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.348 0.652
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.348 0.652
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.348 0.652
L85.8 Other specified epidermal thickening
0.000 0.350 0.650
D62 Acute posthaemorrhagic anaemia
0.000 0.350 0.650
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.351 0.649
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.351 0.649
L42 Pityriasis rosea
0.000 0.353 0.647
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.353 0.647
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.353 0.647
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.353 0.647
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.353 0.647
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.353 0.647
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.353 0.647
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.353 0.647
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.353 0.647
M24 Other specific joint derangements
0.000 0.353 0.646
E88.3 Tumour lysis syndrome
0.000 0.356 0.644
M65.2 Calcific tendinitis
0.000 0.357 0.643
M65.0 Abscess of tendon sheath
0.000 0.357 0.643
E11.4 With neurological complications
0.000 0.357 0.643
E88.9 Metabolic disorder, unspecified
0.000 0.358 0.642
M10 Gout
0.000 0.359 0.641
M32 Systemic lupus erythematosus
0.000 0.361 0.639
M11 Other crystal arthropathies
0.000 0.367 0.633
H61 Other disorders of external ear
0.000 0.367 0.633
E89.4 Postprocedural ovarian failure
0.000 0.367 0.633
L55 Sunburn
0.000 0.368 0.632
M35.0 Sicca syndrome [Sjogren]
0.000 0.368 0.632
E07.1 Dyshormogenetic goitre
0.000 0.368 0.632
E07.0 Hypersecretion of calcitonin
0.000 0.368 0.632
E06.9 Thyroiditis, unspecified
0.000 0.370 0.630
I15.9 Seconday hypertension, unspecified
0.000 0.373 0.626
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.375 0.625
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.375 0.624
H43 Disorders of vitreous body
0.000 0.376 0.624
E05.8 Other thyrotoxicosis
0.000 0.377 0.623
I15.1 Hypertension secondary to other renal disorders
0.000 0.379 0.621
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.379 0.621
E73 Lactose intolerance
0.000 0.380 0.620
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.382 0.618
E83.9 Disorder of mineral metabolism, unspecified
0.451 0.384 0.165
H60 Otitis externa
0.000 0.385 0.615
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.386 0.614
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.387 0.613
I21.4 Acute subendocardial myocardial infarction
0.000 0.388 0.612
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.391 0.609
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.391 0.609
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.391 0.609
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.391 0.609
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.391 0.609
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.391 0.609
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.391 0.609
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.391 0.609
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.392 0.608
E03.1 Congenital hypothyroidism without goitre
0.000 0.393 0.607
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.393 0.607
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.394 0.606
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.394 0.606
E89.5 Postprocedural testicular hypofunction
0.000 0.394 0.606
E89.1 Postprocedural hypoinsulinaemia
0.000 0.394 0.606
M90 Osteopathies in diseases classified elsewhere
0.000 0.395 0.604
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.396 0.604
L87 Transepidermal elimination disorders
0.000 0.396 0.604
L86 Keratoderma in diseases classified elsewhere
0.000 0.396 0.604
I23 Certain current complications following acute myocardial infarction
0.000 0.396 0.603
E83.8 Other disorders of mineral metabolism
0.416 0.397 0.187
E83.2 Disorders of zinc metabolism
0.416 0.397 0.187
E83.0 Disorders of copper metabolism
0.416 0.397 0.187
H35.1 Retinopathy of prematurity
0.000 0.399 0.601
H40.0 Glaucoma suspect
0.000 0.399 0.601
E78.8 Other disorders of lipoprotein metabolism
0.000 0.401 0.599
M30.0 Polyarteritis nodosa
0.000 0.401 0.599
L90 Atrophic disorders of skin
0.000 0.402 0.598
M33 Dermatopolymyositis
0.000 0.402 0.598
M80-M85 Disorders of bone density and structure
0.000 0.402 0.598
L83 Acanthosis nigricans
0.000 0.403 0.597
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.406 0.594
L58 Radiodermatitis
0.000 0.406 0.593
L57.5 Actinic granuloma
0.000 0.408 0.591
L57.3 Poikiloderma of Civatte
0.000 0.408 0.591
L57.2 Cutis rhomboidalis nuchae
0.000 0.408 0.591
L57.1 Actinic reticuloid
0.000 0.408 0.591
M66 Spontaneous rupture of synovium and tendon
0.000 0.409 0.591
D50-D53 Nutritional anaemias
0.000 0.411 0.589
H35.2 Other proliferative retinopathy
0.000 0.413 0.587
M86.98 Osteomyelitis, unspecified (Other)
0.000 0.415 0.585
H46 Optic neuritis
0.000 0.415 0.585
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.416 0.584
M15-M19 Arthrosis
0.000 0.416 0.584
L95.8 Other vasculitis limited to skin
0.000 0.416 0.584
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.416 0.583
H61.0 Perichondritis of external ear
0.000 0.417 0.583
L93 Lupus erythematosus
0.000 0.419 0.581
L20-L30 Dermatitis and eczema
0.000 0.419 0.581
E83.3 Disorders of phosphorus metabolism
0.509 0.419 0.072
H33.4 Traction detachment of retina
0.000 0.420 0.580
M60-M63 Disorders of muscles
0.000 0.423 0.577
M86.6 Other chronic osteomyelitis
0.000 0.423 0.576
M31.9 Necrotising vasculopathy, unspecified
0.000 0.424 0.576
I15.8 Other secondary hypertension
0.000 0.425 0.575
I15.2 Hypertension secondary to endocrine disorders
0.000 0.425 0.575
E80.4 Gilbert's syndrome
0.000 0.427 0.573
E89.3 Postprocedural hypopituitarism
0.000 0.428 0.572
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.428 0.572
I15.0 Renovascular hypertension
0.000 0.428 0.572
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.429 0.571
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.431 0.569
E20-E35 Disorders of other endocrine glands
0.000 0.432 0.568
M94 Other disorders of cartilage
0.000 0.432 0.568
M31.8 Other specified necrotising vasculopathies
0.000 0.433 0.567
M31.7 Microscopic polyangiitis
0.000 0.433 0.567
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.433 0.567
M31.2 Lethal midline granuloma
0.000 0.433 0.567
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.433 0.567
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.433 0.567
M30.2 Juvenile polyarteritis
0.000 0.433 0.567
M14.6 Neuropathic arthropathy
0.000 0.440 0.560
L94.2 Calcinosis cutis
0.000 0.443 0.557
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.443 0.557
M00-M03 Infectious arthropathies
0.000 0.443 0.556
L90.0 Lichen sclerosus et atrophicus
0.000 0.443 0.557
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.444 0.556
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.447 0.553
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.447 0.553
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.447 0.553
E74.2 Disorders of galactose metabolism
0.000 0.447 0.553
E74.1 Disorders of fructose metabolism
0.000 0.447 0.553
E74.0 Glycogen storage disease
0.000 0.447 0.553
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.448 0.552
L28 Lichen simplex chronicus and prurigo
0.000 0.448 0.552
M31.1 Thrombotic microangiopathy
0.000 0.449 0.550
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.450 0.550
H43.3 Other vitreous opacities
0.000 0.450 0.550
D64.4 Congenital dyserythropoietic anaemia
0.000 0.450 0.550
D64.3 Other sideroblastic anaemias
0.000 0.450 0.550
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.450 0.550
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.450 0.550
D64.0 Hereditary sideroblastic anaemia
0.000 0.450 0.550
M18 Arthrosis of first carpometacarpal joint
0.000 0.450 0.550
L88 Pyoderma gangrenosum
0.000 0.451 0.548
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.455 0.544
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.455 0.544
M86.3 Chronic multifocal osteomyelitis
0.000 0.455 0.544
M86.2 Subacute osteomyelitis
0.000 0.455 0.544
M86.0 Acute haematogenous osteomyelitis
0.000 0.455 0.544
H61.8 Other specified disorders of external ear
0.000 0.457 0.543
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.460 0.540
E89.2 Postprocedural hypoparathyroidism
0.000 0.460 0.540
G36.0 Neuromyelitis optica [Devic]
0.539 0.460 0.000
D50 Iron deficiency anaemia
0.000 0.461 0.539
H61.1 Non-infective disorders of pinna
0.000 0.462 0.538
M80 Osteoporosis with pathological fracture
0.000 0.464 0.536
H60.9 Otitis externa, unspecified
0.000 0.466 0.534
E11.0 With coma
0.000 0.467 0.533
L12 Pemphigoid
0.000 0.470 0.530
H60.3 Other infective otitis externa
0.000 0.470 0.530
E65 Localised adiposity
0.000 0.470 0.530
M92 Other juvenile osteochondrosis
0.000 0.470 0.529
M82 Osteoporosis in diseases classified elsewhere
0.000 0.471 0.529

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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