TreeWAS – Variant ID: rs3132954

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.001	0.999
H00.1 Chalazion	0.000	0.001	0.999
E10.1 With ketoacidosis	0.997	0.003	0.000
M06 Other rheumatoid arthritis	0.000	0.005	0.995
E20-E35 Disorders of other endocrine glands	0.992	0.008	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.980	0.020	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.980	0.020	0.000
C83.3 Large cell (diffuse)	0.980	0.020	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.980	0.020	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.978	0.022	0.000
E10.4 With neurological complications	0.977	0.023	0.000
M06.3 Rheumatoid nodule	0.000	0.034	0.966
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.038	0.962
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.042	0.958
G35 Multiple sclerosis	0.000	0.044	0.956
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.050	0.950
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.051	0.949
M05 Seropositive rheumatoid arthritis	0.000	0.055	0.945
E28 Ovarian dysfunction	0.943	0.057	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.059	0.941
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.938	0.062	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.070	0.930
E14 Unspecified diabetes mellitus	0.929	0.071	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.923	0.077	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.912	0.088	0.000
E10.2 With renal complications	0.906	0.094	0.000
E21.3 Hyperparathyroidism, unspecified	0.904	0.096	0.000
C81 Hodgkin's disease	0.901	0.099	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.099	0.901
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.100	0.900
E16 Other disorders of pancreatic internal secretion	0.894	0.106	0.000
E10.8 With unspecified complications	0.894	0.106	0.000
E28.2 Polycystic ovarian syndrome	0.876	0.124	0.000
E16.2 Hypoglycaemia, unspecified	0.874	0.126	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.129	0.871
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.136	0.864
E10.5 With peripheral circulatory complications	0.863	0.137	0.000
C83.1 Small cleaved cell (diffuse)	0.859	0.141	0.000
C81.1 Nodular sclerosis	0.857	0.143	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.856	0.144	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.148	0.852
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.152	0.848
E11 Non-insulin-dependent diabetes mellitus	0.848	0.152	0.000
E40-E46 Malnutrition	0.834	0.166	0.000
H00 Hordeolum and chalazion	0.000	0.173	0.827
E07 Other disorders of thyroid	0.826	0.174	0.000
C83.7 Burkitt's tumour	0.815	0.185	0.000
E10.7 With multiple complications	0.813	0.187	0.000
E34 Other endocrine disorders	0.812	0.188	0.000
E28.3 Primary ovarian failure	0.802	0.198	0.000
E14.1 With ketoacidosis	0.801	0.199	0.000
E27 Other disorders of adrenal gland	0.795	0.205	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.207	0.793
L40.5 Arthropathic psoriasis	0.792	0.208	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.208	0.792
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.208	0.792
E11.3 With ophthalmic complications	0.791	0.209	0.000
E11.1 With ketoacidosis	0.789	0.211	0.000
E14.8 With unspecified complications	0.786	0.214	0.000
E23 Hypofunction and other disorders of pituitary gland	0.785	0.215	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.217	0.783
E14.5 With peripheral circulatory complications	0.774	0.226	0.000
C82.2 Large cell, follicular	0.769	0.231	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.232	0.768
E11.5 With peripheral circulatory complications	0.765	0.235	0.000
C84.5 Other and unspecified T-cell lymphomas	0.764	0.236	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.236	0.764
E22 Hyperfunction of pituitary gland	0.762	0.238	0.000
E14.4 With neurological complications	0.762	0.238	0.000
E26 Hyperaldosteronism	0.761	0.238	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.761	0.239	0.000
E07.8 Other specified disorders of thyroid	0.758	0.242	0.000
E10.0 With coma	0.757	0.243	0.000
M12 Other specific arthropathies	0.000	0.247	0.753
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.746	0.254	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.257	0.743
E27.1 Primary adrenocortical insufficiency	0.742	0.258	0.000
C82.0 Small cleaved cell, follicular	0.740	0.260	0.000
C95 Leukaemia of unspecified cell type	0.739	0.261	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.264	0.736
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.267	0.733
E14.3 With ophthalmic complications	0.728	0.272	0.000
E34.8 Other specified endocrine disorders	0.726	0.274	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.724	0.276	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.722	0.278	0.000
E31 Polyglandular dysfunction	0.721	0.279	0.000
C81.0 Lymphocytic predominance	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E46 Unspecified protein-energy malnutrition	0.715	0.285	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.715	0.285	0.000
E24 Cushing's syndrome	0.715	0.285	0.000
M06.2 Rheumatoid bursitis	0.000	0.287	0.713
M06.1 Adult-onset Still's disease	0.000	0.287	0.713
E35 Disorders of endocrine glands in diseases classified elsewhere	0.711	0.289	0.000
E32 Diseases of thymus	0.711	0.289	0.000
E30 Disorders of puberty, not elsewhere classified	0.711	0.289	0.000
C91 Lymphoid leukaemia	0.711	0.289	0.000
C83.6 Undifferentiated (diffuse)	0.703	0.297	0.000
C83.5 Lymphoblastic (diffuse)	0.703	0.297	0.000
C83.4 Immunoblastic (diffuse)	0.703	0.297	0.000
C83.2 Mixed small and large cell (diffuse)	0.703	0.297	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.703	0.297	0.000
C94 Other leukaemias of specified cell type	0.703	0.297	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.702	0.298	0.000
C85.0 Lymphosarcoma	0.701	0.298	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.700	0.300	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.301	0.699
E06 Thyroiditis	0.697	0.303	0.000
C88 Malignant immunoproliferative diseases	0.694	0.306	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.307	0.693
M06.38 Rheumatoid nodule (Other)	0.000	0.307	0.693
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.307	0.693
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.307	0.693
M06.33 Rheumatoid nodule (Forearm)	0.000	0.307	0.693
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.307	0.693
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.310	0.690
E23.7 Disorder of pituitary gland, unspecified	0.686	0.314	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.315	0.685
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.319	0.681
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.319	0.681
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.319	0.681
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.319	0.681
C85.1 B-cell lymphoma, unspecified	0.680	0.320	0.000
E20 Hypoparathyroidism	0.678	0.322	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.322	0.678
M05.2 Rheumatoid vasculitis	0.000	0.322	0.678
M05.1 Rheumatoid lung disease	0.000	0.322	0.678
M05.0 Felty's syndrome	0.000	0.322	0.678
E28.9 Ovarian dysfunction, unspecified	0.676	0.324	0.000
E28.8 Other ovarian dysfunction	0.676	0.324	0.000
E28.1 Androgen excess	0.676	0.324	0.000
E28.0 Oestrogen excess	0.676	0.324	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.325	0.674
M08 Juvenile arthritis	0.000	0.325	0.674
C83.0 Small cell (diffuse)	0.673	0.327	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.327	0.673
E15 Nondiabetic hypoglycaemic coma	0.673	0.327	0.000
C91.9 Lymphoid leukaemia, unspecified	0.669	0.331	0.000
E27.8 Other specified disorders of adrenal gland	0.668	0.332	0.000
E14.7 With multiple complications	0.666	0.334	0.000
E14.0 With coma	0.666	0.334	0.000
C86 Other specified types of T/NK-cell lymphoma	0.666	0.334	0.000
E21.4 Other specified disorders of parathyroid gland	0.661	0.338	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.658	0.341	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.658	0.342	0.000
C81.2 Mixed cellularity	0.656	0.344	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.344	0.656
E21.2 Other hyperparathyroidism	0.655	0.344	0.000
C82.6 Cutaneous follicle centre lymphoma	0.654	0.346	0.000
C82.5 Diffuse follicle centre lymphoma	0.654	0.346	0.000
E25 Adrenogenital disorders	0.653	0.346	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.347	0.653
E14.2 Withrenal complications	0.649	0.351	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.646	0.354	0.000
C81.3 Lymphocytic depletion	0.646	0.354	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.646	0.354	0.000
E13 Other specified diabetes mellitus	0.642	0.357	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.641	0.359	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.641	0.359	0.000
E16.4 Abnormal secretion of gastrin	0.641	0.359	0.000
E16.3 Increased secretion of glucagon	0.641	0.359	0.000
E34.9 Endocrine disorder, unspecified	0.640	0.360	0.000
E11.2 With renal complications	0.635	0.365	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.633	0.366	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.632	0.368	0.000
E22.0 Acromegaly and pituitary gigantism	0.627	0.373	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.375	0.625
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.375	0.625
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.375	0.625
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.375	0.625
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.375	0.625
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.375	0.625
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.375	0.625
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.376	0.624
E23.6 Other disorders of pituitary gland	0.620	0.380	0.000
E26.9 Hyperaldosteronism, unspecified	0.620	0.380	0.000
C95.0 Acute leukaemia of unspecified cell type	0.619	0.381	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.383	0.617
C84.9 Mature T/NK-cell lymphoma, unspecified	0.614	0.386	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.614	0.386	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.614	0.386	0.000
C84.3 Lymphoepithelioid lymphoma	0.614	0.386	0.000
C84.2 T-zone lymphoma	0.614	0.386	0.000
C84.1 Sezary's diease	0.614	0.386	0.000
C84.4 Peripheral T-cell lymphoma	0.613	0.387	0.000
M12.2 Villonodular synovitis (pigmented)	0.000	0.391	0.609
E11.7 With multiple complications	0.608	0.392	0.000
L40 Psoriasis	0.605	0.395	0.000
E11.6 With other specified complications	0.602	0.398	0.000
C82.3 Follicular lymphoma grade IIIa	0.601	0.399	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.598	0.402	0.000
E45 Retarded development following protein-energy malnutrition	0.598	0.402	0.000
E43 Unspecified severe protein-energy malnutrition	0.598	0.402	0.000
E42 Marasmic kwashiorkor	0.598	0.402	0.000
E41 Nutritional marasmus	0.598	0.402	0.000
E40 Kwashiorkor	0.598	0.402	0.000
C82.4 Follicular lymphoma grade IIIb	0.594	0.406	0.000
E07.1 Dyshormogenetic goitre	0.592	0.408	0.000
E07.0 Hypersecretion of calcitonin	0.592	0.408	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.408	0.592
E24.2 Drug-induced Cushing's syndrome	0.591	0.409	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.411	0.589
E27.9 Disorder of adrenal gland, unspecified	0.586	0.414	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.414	0.586
E34.5 Androgen resistance syndrome	0.582	0.418	0.000
E34.4 Constitutional tall stature	0.582	0.418	0.000
E34.3 Short stature, not elsewhere classified	0.582	0.418	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.582	0.418	0.000
E34.1 Other hypersecretion of intestinal hormones	0.582	0.418	0.000
M12.3 Palindromic rheumatism	0.000	0.419	0.581
E14.6 With other specified complications	0.578	0.422	0.000
L40-L45 Papulosquamous disorders	0.578	0.422	0.000
C90.3 Solitary plasmacytoma	0.576	0.424	0.000
L43 Lichen planus	0.575	0.425	0.000
C91.5 Adult T-cell leukaemia	0.574	0.426	0.000
L43.9 Lichen planus, unspecified	0.574	0.426	0.000
E27.5 Adrenomedullary hyperfunction	0.570	0.430	0.000
E27.0 Other adrenocortical overactivity	0.570	0.430	0.000
C93 Monocytic leukaemia	0.570	0.430	0.000
C84.0 Mycosis fungoides	0.570	0.430	0.000
E22.1 Hyperprolactinaemia	0.569	0.431	0.000
E10.6 With other specified complications	0.564	0.436	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.563	0.437	0.000
E23.1 Drug-induced hypopituitarism	0.563	0.437	0.000
J45 Asthma	0.000	0.440	0.560
C81.7 Other Hodgkin's disease	0.557	0.443	0.000
E29 Testicular dysfunction	0.557	0.443	0.000
C81.9 Hodgkin's disease, unspecified	0.549	0.451	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.546	0.454	0.000
E22.8 Other hyperfunction of pituitary gland	0.546	0.454	0.000
E26.8 Other hyperaldosteronism	0.546	0.454	0.000
E26.1 Secondary hyperaldosteronism	0.546	0.454	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.544	0.456	0.000
G36 Other acute disseminated demyelination	0.000	0.460	0.540
M12.5 Traumatic arthropathy	0.000	0.460	0.540
M12.4 Intermittent hydrarthrosis	0.000	0.460	0.540
M12.1 Kaschin-Beck disease	0.000	0.460	0.540
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.460	0.540
E05.8 Other thyrotoxicosis	0.540	0.460	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.461	0.539
E23.2 Diabetes insipidus	0.538	0.462	0.000
E06.5 Other chronic thyroiditis	0.536	0.464	0.000
E03 Other hypothyroidism	0.535	0.465	0.000
E24.0 Pituitary-dependent Cushing's disease	0.531	0.469	0.000
C95.7 Other leukaemia of unspecified cell type	0.530	0.470	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.530	0.470	0.000
E06.3 Autoimmune thyroiditis	0.528	0.472	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.472	0.528
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.472	0.528
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.472	0.528
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.472	0.528
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.472	0.528
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.472	0.528
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.472	0.528
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.472	0.528
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.472	0.528
E31.0 Autoimmune polyglandular failure	0.526	0.473	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.526	0.474	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.524	0.476	0.000
E31.9 Polyglandular dysfunction, unspecified	0.517	0.483	0.000
E31.8 Other polyglandular dysfunction	0.517	0.483	0.000
E31.1 Polyglandular hyperfunction	0.517	0.483	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E24.8 Other Cushing's syndrome	0.512	0.487	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.512	0.487	0.000
E24.3 Ectopic ACTH syndrome	0.512	0.487	0.000
E24.1 Nelson's syndrome	0.512	0.487	0.000
E11.8 With unspecified complications	0.512	0.488	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.488	0.511
M06.18 Adult-onset Still's disease (Other)	0.000	0.488	0.511
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.488	0.511
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.488	0.511
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.488	0.511
M06.14 Adult-onset Still's disease (Hand)	0.000	0.488	0.511
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.488	0.511
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.488	0.511
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.488	0.511
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.488	0.511
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.488	0.511
M06.28 Rheumatoid bursitis (Other)	0.000	0.488	0.511
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.488	0.511
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.488	0.511
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.488	0.511
M06.24 Rheumatoid bursitis (Hand)	0.000	0.488	0.511
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.488	0.511
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.488	0.511
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.488	0.511
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.488	0.511
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.489	0.511
E26.0 Primary hyperaldosteronism	0.510	0.490	0.000
E30.9 Disorder of puberty, unspecified	0.510	0.490	0.000
E30.8 Other disorders of puberty	0.510	0.490	0.000
E30.1 Precocious puberty	0.510	0.490	0.000
E30.0 Delayed puberty	0.510	0.490	0.000
E32.9 Disease of thymus, unspecified	0.510	0.490	0.000
E32.8 Other diseases of thymus	0.510	0.490	0.000
E32.1 Abscess of thymus	0.510	0.490	0.000
E32.0 Persistent hyperplasia of thymus	0.510	0.490	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.510	0.490	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.510	0.490	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.510	0.490	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.510	0.490	0.000
C91.7 Other lymphoid leukaemia	0.510	0.490	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.510	0.490	0.000
C91.3 Prolymphocytic leukaemia	0.510	0.490	0.000
C91.2 Subacute lymphocytic leukaemia	0.510	0.490	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.492	0.508
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.492	0.508
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.493	0.506
C94.7 Other specified leukaemias	0.504	0.496	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.504	0.496	0.000
C94.5 Acute myelofibrosis	0.504	0.496	0.000
C94.4 Acute panmyelosis	0.504	0.496	0.000
C94.3 Mast cell leukaemia	0.504	0.496	0.000
C94.2 Acute megakaryoblastic leukaemia	0.504	0.496	0.000
C94.1 Chronic erythraemia	0.504	0.496	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.504	0.496	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.504	0.496	0.000
C96.8 Histiocytic sarcoma	0.504	0.496	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.504	0.496	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.504	0.496	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.504	0.496	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.504	0.496	0.000
C96.3 True histiocytic lymphoma	0.504	0.496	0.000
C96.2 Malignant mast cell tumour	0.504	0.496	0.000
C96.1 Malignant histiocytosis	0.504	0.496	0.000
C96.0 Letterer-Siwe disease	0.504	0.496	0.000
E16.1 Other hypoglycaemia	0.503	0.497	0.000
E06.4 Drug-induced thyroiditis	0.500	0.500	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.500	0.500	0.000
E06.1 Subacute thyroiditis	0.500	0.500	0.000
E06.0 Acute thyroiditis	0.500	0.500	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.497	0.502	0.000
C88.7 Other malignant immunoproliferative diseases	0.497	0.502	0.000
C88.3 Immunoproliferative small intestinal disease	0.497	0.502	0.000
C88.2 Gamma heavy chain disease	0.497	0.502	0.000
C88.1 Alpha heavy chain disease	0.497	0.502	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.000	0.503	0.497
G37.5 Concentric sclerosis [Balo]	0.000	0.509	0.491
G37.4 Subacute necrotising myelitis	0.000	0.509	0.491
G37.2 Central pontine myelinolysis	0.000	0.509	0.491
G37.1 Central demyelination of corpus callosum	0.000	0.509	0.491
G37.0 Diffuse sclerosis	0.000	0.509	0.491
E20.8 Other hypoparathyroidism	0.486	0.514	0.000
E20.1 Pseudohypoparathyroidism	0.486	0.514	0.000
E20.0 Idiopathic hypoparathyroidism	0.486	0.514	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.514	0.486
M05.08 Felty's syndrome (Other)	0.000	0.514	0.486
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.514	0.486
M05.06 Felty's syndrome (Lower leg)	0.000	0.514	0.486
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.514	0.486
M05.04 Felty's syndrome (Hand)	0.000	0.514	0.486
M05.03 Felty's syndrome (Forearm)	0.000	0.514	0.486
M05.02 Felty's syndrome (Upper arm)	0.000	0.514	0.486
M05.01 Felty's syndrome (Shoulder region)	0.000	0.514	0.486
M05.00 Felty's syndrome (Multiple sites)	0.000	0.514	0.486
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.514	0.486
M05.18 Rheumatoid lung disease (Other)	0.000	0.514	0.486
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.514	0.486
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.514	0.486
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.514	0.486
M05.14 Rheumatoid lung disease (Hand)	0.000	0.514	0.486
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.514	0.486
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.514	0.486
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.514	0.486
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.514	0.486
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.514	0.486
M05.28 Rheumatoid vasculitis (Other)	0.000	0.514	0.486
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.514	0.486
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.514	0.486
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.514	0.486
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.514	0.486
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.514	0.486
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.514	0.486
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.514	0.486
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.514	0.486
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.514	0.486
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.514	0.486
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.514	0.486
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.514	0.486
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.514	0.486
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.514	0.486
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.514	0.486
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.514	0.486
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.514	0.486
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.514	0.486
M08.9 Juvenile arthritis, unspecified	0.000	0.516	0.484
M08.8 Other juvenile arthritis	0.000	0.516	0.484
M08.4 Pauciarticular juvenile arthritis	0.000	0.516	0.484
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.516	0.484
M08.2 Juvenile arthritis with systemic onset	0.000	0.516	0.484
M08.1 Juvenile ankylosing spondylitis	0.000	0.516	0.484
M08.0 Juvenile rheumatoid arthritis	0.000	0.516	0.484
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.516	0.484
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.516	0.484
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.516	0.484
M09.0 Juvenile arthritis in psoriasis	0.000	0.516	0.484
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.517	0.483
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.517	0.483
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.517	0.483
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.517	0.483
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.517	0.483
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.521	0.479
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.477	0.522	0.000
C86.4 Blastic NK-cell lymphoma	0.477	0.522	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.477	0.522	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.477	0.522	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.477	0.522	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.477	0.522	0.000
E27.2 Addisonian crisis	0.471	0.529	0.000
E25.9 Adrenogenital disorder, unspecified	0.469	0.531	0.000
E25.8 Other adrenogenital disorders	0.469	0.531	0.000
L40.3 Pustulosis palmaris et plantaris	0.468	0.532	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.468	0.532	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.468	0.532	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.001	0.532	0.467
C90.1 Plasma cell leukaemia	0.468	0.532	0.000
E14.9 Without complications	0.466	0.534	0.000
M11 Other crystal arthropathies	0.000	0.534	0.465
E13.8 With unspecified complications	0.461	0.539	0.000
E13.7 With multiple complications	0.461	0.539	0.000
E13.6 With other specified complications	0.461	0.539	0.000
E13.5 With peripheral circulatory complications	0.461	0.539	0.000
E13.4 With neurological complications	0.461	0.539	0.000
E13.2 With renal complications	0.461	0.539	0.000
E13.1 With ketoacidosis	0.461	0.539	0.000
E13.0 With coma	0.461	0.539	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.542	0.458
L43.0 Hypertrophic lichen planus	0.456	0.544	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.456	0.544	0.000
E13.9 Without complications	0.454	0.546	0.000
L44 Other papulosquamous disorders	0.453	0.547	0.000
E20.9 Hypoparathyroidism, unspecified	0.452	0.547	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.550	0.450
C85.7 Other specified types of non-Hodgkin's lymphoma	0.450	0.550	0.000
J45.8 Mixed asthma	0.000	0.551	0.449
K90 Intestinal malabsorption	0.449	0.551	0.000
L40.1 Generalised pustular psoriasis	0.446	0.554	0.000
J45.1 Nonallergic asthma	0.000	0.557	0.443
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.557	0.442
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.557	0.442
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.557	0.442
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.557	0.442
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.557	0.442
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.557	0.442
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.557	0.442
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.557	0.442
C86.5 Angioimmunoblastic T-cell lymphoma	0.441	0.559	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.000	0.563	0.437
M12.28 Villonodular synovitis (pigmented) (Other)	0.000	0.563	0.437
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.000	0.563	0.437
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.000	0.563	0.437
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.000	0.563	0.437
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.000	0.563	0.437
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.000	0.563	0.437
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.000	0.563	0.437
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.434	0.566	0.000
L40.2 Acrodermatitis continua	0.434	0.566	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.567	0.432
C91.0 Acute lymphoblastic leukaemia	0.431	0.569	0.000
E44.1 Mild protein-energy malnutrition	0.429	0.571	0.000
E44.0 Moderate protein-energy malnutrition	0.429	0.571	0.000
M14.2 Diabetic arthropathy	0.000	0.573	0.427
M14.4 Arthropathy in amyloidosis	0.000	0.577	0.422

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations