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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132958
log Bayes Factor = 219.016
Chromosome 6   position 32,297,901  (GRCh37) Explore rs3132958 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
G37 Other demyelinating diseases of central nervous system
0.995 0.004 0.000
# Top node
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
I10 Essential (primary) hypertension
0.000 0.006 0.994
M35 Other systemic involvement of connective tissue
0.000 0.006 0.994
I10-I15 Hypertensive diseases
0.000 0.006 0.994
Chapter VII Diseases of the eye and adnexa
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
E10.5 With peripheral circulatory complications
0.000 0.007 0.993
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.008 0.992
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
J33.8 Other polyp of sinus
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.009 0.991
M20-M25 Other joint disorders
0.000 0.013 0.987
Chapter IX Diseases of the circulatory system
0.000 0.013 0.987
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.016 0.984
L43 Lichen planus
0.000 0.017 0.983
E10.2 With renal complications
0.000 0.025 0.975
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.030 0.970
E06 Thyroiditis
0.000 0.030 0.970
I22 Subsequent myocardial infarction
0.000 0.031 0.969
I20-I25 Ischaemic heart diseases
0.000 0.032 0.968
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.041 0.959
L43.9 Lichen planus, unspecified
0.000 0.042 0.958
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.044 0.956
I12 Hypertensive renal disease
0.000 0.046 0.954
E10.8 With unspecified complications
0.000 0.046 0.954
E06.3 Autoimmune thyroiditis
0.000 0.048 0.952
H40-H42 Glaucoma
0.000 0.048 0.952
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.050 0.950
M45-M49 Spondylopathies
0.000 0.051 0.949
M45 Ankylosing spondylitis
0.000 0.052 0.948
H34 Retinal vascular occlusions
0.000 0.052 0.948
M06.0 Seronegative rheumatoid arthritis
0.000 0.054 0.946
M34 Systemic sclerosis
0.000 0.054 0.946
M65-M68 Disorders of synovium and tendon
0.000 0.056 0.944
M06.3 Rheumatoid nodule
0.000 0.057 0.943
E10.0 With coma
0.000 0.058 0.942
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.060 0.940
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.062 0.938
I12.9 Hypertensive renal disease without renal failure
0.000 0.063 0.937
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.064 0.936
M65 Synovitis and tenosynovitis
0.000 0.071 0.929
H35 Other retinal disorders
0.000 0.074 0.926
H40 Glaucoma
0.000 0.078 0.922
H40.9 Glaucoma, unspecified
0.000 0.082 0.918
E78.2 Mixed hyperlipidaemia
0.000 0.090 0.910
M06.4 Inflammatory polyarthropathy
0.000 0.093 0.907
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.094 0.906
E07 Other disorders of thyroid
0.000 0.095 0.905
E11.5 With peripheral circulatory complications
0.000 0.099 0.901
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.102 0.898
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.107 0.893
E78.1 Pure hyperglyceridaemia
0.000 0.107 0.893
E11.2 With renal complications
0.000 0.113 0.887
H35.4 Peripheral retinal degeneration
0.000 0.116 0.884
H35.8 Other specified retinal disorders
0.000 0.117 0.883
E88 Other metabolic disorders
0.000 0.117 0.883
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.118 0.882
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.135 0.865
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.137 0.863
M34.1 CR(E)ST syndrome
0.000 0.138 0.862
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.138 0.862
G37.8 Other specified demyelinating diseases of central nervous system
0.861 0.139 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.142 0.858
L40.8 Other psoriasis
0.000 0.145 0.855
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.145 0.855
M35.7 Hypermobility syndrome
0.000 0.146 0.854
L43.8 Other lichen planus
0.000 0.146 0.854
M35.1 Other overlap syndromes
0.000 0.147 0.853
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.149 0.851
M34.9 Systemic sclerosis, unspecified
0.000 0.154 0.846
H34.8 Other retinal vascular occlusions
0.000 0.159 0.841
M06.34 Rheumatoid nodule (Hand)
0.000 0.164 0.836
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.165 0.835
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.169 0.831
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.171 0.829
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.174 0.826
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.175 0.825
E07.9 Disorder of thyroid, unspecified
0.000 0.179 0.821
H34.2 Other retinal artery occlusions
0.000 0.182 0.818
E10.6 With other specified complications
0.000 0.183 0.817
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.190 0.810
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.190 0.810
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.190 0.810
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.193 0.807
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.196 0.804
E11.8 With unspecified complications
0.000 0.202 0.798
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.203 0.797
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.205 0.795
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.208 0.792
E14.4 With neurological complications
0.000 0.209 0.791
E03.8 Other specified hypothyroidism
0.000 0.211 0.789
H43-H45 Disorders of vitreous body and globe
0.000 0.212 0.788
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.213 0.787
I15 Secondary hypertension
0.000 0.213 0.787
M30 Polyarteritis nodosa and related conditions
0.000 0.223 0.777
E83 Disorders of mineral metabolism
0.355 0.226 0.419
E74 Other disorders of carbohydrate metabolism
0.000 0.226 0.774
D64.9 Anaemia, unspecified
0.000 0.228 0.772
I22.8 Subsequent myocardial infarction of other sites
0.000 0.230 0.770
H35.6 Retinal haemorrhage
0.000 0.232 0.768
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.234 0.766
L57.0 Actinic keratosis
0.000 0.237 0.763
M35.2 Behcet's disease
0.000 0.238 0.761
D64 Other anaemias
0.000 0.240 0.760
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.241 0.759
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.242 0.758
D60-D64 Aplastic and other anaemias
0.000 0.243 0.757
E14.5 With peripheral circulatory complications
0.000 0.247 0.753
E89.0 Postprocedural hypothyroidism
0.000 0.247 0.753
H35.7 Separation of retinal layers
0.000 0.251 0.749
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.255 0.745
Chapter VIII Diseases of the ear and mastoid process
0.000 0.258 0.742
H40.4 Glaucoma secondary to eye inflammation
0.000 0.259 0.741
H40.5 Glaucoma secondary to other eye disorders
0.000 0.262 0.737
M31 Other necrotising vasculopathies
0.000 0.263 0.737
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.264 0.736
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.733 0.267 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.268 0.732
E14.2 Withrenal complications
0.000 0.269 0.731
G36 Other acute disseminated demyelination
0.729 0.271 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.275 0.725
M65.1 Other infective (teno)synovitis
0.000 0.276 0.724
H43 Disorders of vitreous body
0.000 0.276 0.724
H34.9 Retinal vascular occlusion, unspecified
0.000 0.276 0.723
M14 Arthropathies in other diseases classified elsewhere
0.000 0.277 0.723
H34.1 Central retinal artery occlusion
0.000 0.279 0.721
H30 Chorioretinal inflammation
0.000 0.280 0.720
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.281 0.719
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.715
M07.2 Psoriatic spondylitis
0.000 0.284 0.715
M07.1 Arthritis mutilans
0.000 0.284 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.715
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.715
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.286 0.714
E40-E46 Malnutrition
0.000 0.287 0.713
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.287 0.713
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.287 0.713
M35.5 Multifocal fibrosclerosis
0.000 0.287 0.713
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.287 0.713
I13 Hypertensive heart and renal disease
0.000 0.288 0.712
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.288 0.712
L40.0 Psoriasis vulgaris
0.000 0.292 0.708
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.292 0.708
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.293 0.707
H60-H62 Diseases of external ear
0.000 0.294 0.706
L43.3 Subacute (active) lichen planus
0.000 0.295 0.705
L43.2 Lichenoid drug reaction
0.000 0.295 0.705
L43.1 Bullous lichen planus
0.000 0.295 0.705
L43.0 Hypertrophic lichen planus
0.000 0.295 0.705
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.296 0.704
E88.2 Lipomatosis, not elsewhere classified
0.000 0.296 0.704
E88.8 Other specified metabolic disorders
0.000 0.297 0.703
H33 Retinal detachments and breaks
0.000 0.297 0.703
E70 Disorders of aromatic amino-acid metabolism
0.000 0.299 0.701
I11 Hypertensive heart disease
0.000 0.299 0.701
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.300 0.700
E13 Other specified diabetes mellitus
0.000 0.302 0.698
E07.8 Other specified disorders of thyroid
0.000 0.303 0.697
E11.6 With other specified complications
0.000 0.304 0.696
E06.5 Other chronic thyroiditis
0.000 0.304 0.695
E06.4 Drug-induced thyroiditis
0.000 0.304 0.695
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.304 0.695
E06.1 Subacute thyroiditis
0.000 0.304 0.695
E06.0 Acute thyroiditis
0.000 0.304 0.695
M34.8 Other forms of systemic sclerosis
0.000 0.306 0.693
E79 Disorders of purine and pyrimidine metabolism
0.000 0.308 0.692
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.309 0.691
M49 Spondylopathies in diseases classified elsewhere
0.000 0.312 0.688
H42 Glaucoma in diseases classified elsewhere
0.000 0.318 0.682
E16.1 Other hypoglycaemia
0.000 0.318 0.681
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.320 0.680
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.320 0.680
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.320 0.680
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.320 0.680
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.320 0.680
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.320 0.680
H34.0 Transient retinal artery occlusion
0.000 0.320 0.679
H35.2 Other proliferative retinopathy
0.000 0.321 0.679
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.321 0.679
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.321 0.679
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.321 0.679
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.321 0.679
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.321 0.679
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.321 0.679
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.322 0.678
M34.0 Progressive systemic sclerosis
0.000 0.322 0.678
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.323 0.677
E78.4 Other hyperlipidaemia
0.000 0.323 0.677
E11.4 With neurological complications
0.000 0.323 0.677
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.324 0.676
M06.38 Rheumatoid nodule (Other)
0.000 0.324 0.676
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.324 0.676
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.324 0.676
M06.33 Rheumatoid nodule (Forearm)
0.000 0.324 0.676
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.324 0.676
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.324 0.676
M12 Other specific arthropathies
0.000 0.324 0.676
M91-M94 Chondropathies
0.000 0.326 0.674
M07.6 Other enteropathic arthropathies
0.000 0.331 0.668
E84 Cystic fibrosis
0.000 0.334 0.666
M65.2 Calcific tendinitis
0.000 0.334 0.666
M65.0 Abscess of tendon sheath
0.000 0.334 0.666
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.335 0.665
H35.1 Retinopathy of prematurity
0.000 0.336 0.664
H40.6 Glaucoma secondary to drugs
0.000 0.339 0.661
H40.3 Glaucoma secondary to eye trauma
0.000 0.339 0.661
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.659
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.344 0.656
L10-L14 Bullous disorders
0.000 0.346 0.654
M86-M90 Other osteopathies
0.000 0.348 0.652
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.350 0.650
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.350 0.650
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.350 0.650
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.350 0.650
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.350 0.650
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.350 0.650
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.350 0.650
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.350 0.650
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.350 0.650
H61 Other disorders of external ear
0.000 0.351 0.649
E07.1 Dyshormogenetic goitre
0.000 0.351 0.649
E07.0 Hypersecretion of calcitonin
0.000 0.351 0.649
E06.9 Thyroiditis, unspecified
0.000 0.352 0.648
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.353 0.647
H43.3 Other vitreous opacities
0.000 0.357 0.643
M66 Spontaneous rupture of synovium and tendon
0.000 0.360 0.640
H43.9 Disorder of vitreous body, unspecified
0.000 0.362 0.638
E88.3 Tumour lysis syndrome
0.000 0.364 0.636
M32 Systemic lupus erythematosus
0.000 0.365 0.635
E88.9 Metabolic disorder, unspecified
0.000 0.367 0.633
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.367 0.633
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.368 0.632
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.368 0.632
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.368 0.632
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.368 0.632
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.368 0.632
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.368 0.632
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.368 0.632
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.368 0.632
M11 Other crystal arthropathies
0.000 0.371 0.629
H40.1 Primary open-angle glaucoma
0.000 0.380 0.620
E89.4 Postprocedural ovarian failure
0.000 0.381 0.619
H33.3 Retinal breaks without detachment
0.000 0.381 0.619
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.382 0.618
L42 Pityriasis rosea
0.000 0.383 0.617
H60 Otitis externa
0.000 0.383 0.617
I15.9 Seconday hypertension, unspecified
0.000 0.383 0.617
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.387 0.613
L55 Sunburn
0.000 0.387 0.613
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.387 0.613
M31.6 Other giant cell arteritis
0.000 0.388 0.612
E05.8 Other thyrotoxicosis
0.000 0.390 0.609
E73 Lactose intolerance
0.000 0.393 0.606
I15.1 Hypertension secondary to other renal disorders
0.000 0.396 0.604
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.401 0.599
M86 Osteomyelitis
0.000 0.401 0.598
E89.3 Postprocedural hypopituitarism
0.000 0.402 0.598
I23 Certain current complications following acute myocardial infarction
0.000 0.406 0.594
M33 Dermatopolymyositis
0.000 0.408 0.592
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.409 0.591
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.409 0.591
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.409 0.591
E89.5 Postprocedural testicular hypofunction
0.000 0.409 0.591
E89.1 Postprocedural hypoinsulinaemia
0.000 0.409 0.591
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.409 0.591
M30.0 Polyarteritis nodosa
0.000 0.409 0.591
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.409 0.591
M60-M63 Disorders of muscles
0.000 0.413 0.587
D62 Acute posthaemorrhagic anaemia
0.000 0.414 0.586
H61.0 Perichondritis of external ear
0.000 0.416 0.584
M14.6 Neuropathic arthropathy
0.000 0.417 0.583
M35.0 Sicca syndrome [Sjogren]
0.000 0.420 0.580
H35.5 Hereditary retinal dystrophy
0.000 0.421 0.579
E65-E68 Obesity and other hyperalimentation
0.000 0.421 0.579
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.422 0.578
M80-M85 Disorders of bone density and structure
0.000 0.422 0.578
I21 Acute myocardial infarction
0.000 0.423 0.577
I24 Other acute ischaemic heart diseases
0.000 0.430 0.570
H61.8 Other specified disorders of external ear
0.000 0.430 0.570
L57.5 Actinic granuloma
0.000 0.430 0.570
L57.3 Poikiloderma of Civatte
0.000 0.430 0.570
L57.2 Cutis rhomboidalis nuchae
0.000 0.430 0.570
L57.1 Actinic reticuloid
0.000 0.430 0.570
M86.9 Osteomyelitis, unspecified
0.000 0.431 0.569
E11.0 With coma
0.000 0.432 0.568
H40.0 Glaucoma suspect
0.000 0.433 0.567
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.435 0.565
I15.8 Other secondary hypertension
0.000 0.436 0.564
I15.2 Hypertension secondary to endocrine disorders
0.000 0.436 0.564
H33.4 Traction detachment of retina
0.000 0.437 0.563
E78.8 Other disorders of lipoprotein metabolism
0.000 0.438 0.562
E03.1 Congenital hypothyroidism without goitre
0.000 0.438 0.561
M00-M03 Infectious arthropathies
0.000 0.440 0.559
L58 Radiodermatitis
0.000 0.440 0.559
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.443 0.557
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.443 0.557
M30.2 Juvenile polyarteritis
0.000 0.443 0.557
E83.8 Other disorders of mineral metabolism
0.255 0.445 0.301
E83.2 Disorders of zinc metabolism
0.255 0.445 0.301
E83.0 Disorders of copper metabolism
0.255 0.445 0.301
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.445 0.555
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.445 0.555
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.445 0.555
E74.2 Disorders of galactose metabolism
0.000 0.445 0.555
E74.1 Disorders of fructose metabolism
0.000 0.445 0.555
E74.0 Glycogen storage disease
0.000 0.445 0.555
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.445 0.555
H61.1 Non-infective disorders of pinna
0.000 0.445 0.555
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.448 0.552
M31.3 Wegener's granulomatosis
0.000 0.448 0.552
E20-E35 Disorders of other endocrine glands
0.000 0.449 0.551
I15.0 Renovascular hypertension
0.000 0.449 0.551
M10 Gout
0.000 0.450 0.550
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.453 0.547
D64.4 Congenital dyserythropoietic anaemia
0.000 0.455 0.545
D64.3 Other sideroblastic anaemias
0.000 0.455 0.545
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.455 0.545
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.455 0.545
D64.0 Hereditary sideroblastic anaemia
0.000 0.455 0.545
H60.3 Other infective otitis externa
0.000 0.456 0.544
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.457 0.543
E83.9 Disorder of mineral metabolism, unspecified
0.276 0.458 0.266
M31.9 Necrotising vasculopathy, unspecified
0.000 0.462 0.538
G36.0 Neuromyelitis optica [Devic]
0.538 0.462 0.000
M31.1 Thrombotic microangiopathy
0.000 0.464 0.535
E80.4 Gilbert's syndrome
0.000 0.466 0.534
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.467 0.533
E89.2 Postprocedural hypoparathyroidism
0.000 0.468 0.532
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.469 0.531
M31.8 Other specified necrotising vasculopathies
0.000 0.471 0.528
M31.7 Microscopic polyangiitis
0.000 0.471 0.528
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.471 0.528
M31.2 Lethal midline granuloma
0.000 0.471 0.528
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.473 0.527
H43.2 Crystalline deposits in vitreous body
0.000 0.474 0.526
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.476 0.524
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.476 0.524
I00 Rheumatic fever without mention of heart involvement
0.000 0.476 0.523
G36.9 Acute disseminated demyelination, unspecified
0.523 0.477 0.000
G36.8 Other specified acute disseminated demyelination
0.523 0.477 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.523 0.477 0.000
H30.9 Chorioretinal inflammation, unspecified
0.000 0.479 0.520
I70 Atherosclerosis
0.000 0.480 0.520
M65.19 Other infective (teno)synovitis (Site unspecified)
0.000 0.480 0.519
M65.18 Other infective (teno)synovitis (Other)
0.000 0.480 0.519
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.000 0.480 0.519
M65.16 Other infective (teno)synovitis (Lower leg)
0.000 0.480 0.519
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.000 0.480 0.519
M65.13 Other infective (teno)synovitis (Forearm)
0.000 0.480 0.519
M65.12 Other infective (teno)synovitis (Upper arm)
0.000 0.480 0.519
M65.11 Other infective (teno)synovitis (Shoulder region)
0.000 0.480 0.519
M65.10 Other infective (teno)synovitis (Multiple sites)
0.000 0.480 0.519
H43.0 Vitreous prolapse
0.000 0.481 0.519
H46 Optic neuritis
0.000 0.481 0.519
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.481 0.518
M14.4 Arthropathy in amyloidosis
0.000 0.481 0.518
M14.3 Lipoid dermatoarthritis
0.000 0.481 0.518
M14.2 Diabetic arthropathy
0.000 0.481 0.518
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.481 0.518
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.481 0.518
M82 Osteoporosis in diseases classified elsewhere
0.000 0.482 0.518
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.483 0.517
H30.8 Other chorioretinal inflammations
0.000 0.484 0.516
H30.2 Posterior cyclitis
0.000 0.484 0.516
H30.1 Disseminated chorioretinal inflammation
0.000 0.484 0.516
H30.0 Focal chorioretinal inflammation
0.000 0.484 0.516
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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