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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3134603
log Bayes Factor = 147.34
Chromosome 6   position 32,126,002  (GRCh37) Explore rs3134603 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
I30-I52 Other forms of heart disease
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
L43 Lichen planus
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
L43.9 Lichen planus, unspecified
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
I35 Nonrheumatic aortic valve disorders
0.000 0.003 0.997
Chapter VII Diseases of the eye and adnexa
0.000 0.003 0.997
K51.9 Ulcerative colitis, unspecified
0.997 0.003 0.000
E10.4 With neurological complications
0.000 0.003 0.997
I35.0 Aortic (valve) stenosis
0.000 0.003 0.997
J45.9 Asthma, unspecified
0.000 0.003 0.997
K51 Ulcerative colitis
0.996 0.004 0.000
G37 Other demyelinating diseases of central nervous system
0.996 0.004 0.000
I47 Paroxysmal tachycardia
0.000 0.004 0.996
I20.0 Unstable angina
0.000 0.005 0.995
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.007 0.993
M05 Seropositive rheumatoid arthritis
0.000 0.008 0.992
G37.9 Demyelinating disease of central nervous system, unspecified
0.992 0.008 0.000
I25.1 Atherosclerotic heart disease
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.008 0.992
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.010 0.990
E14.3 With ophthalmic complications
0.000 0.011 0.989
E70-E90 Metabolic disorders
0.000 0.011 0.989
K70-K77 Diseases of liver
0.000 0.012 0.988
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.012 0.988
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.013 0.987
K55-K64 Other diseases of intestines
0.000 0.015 0.985
K51.3 Ulcerative (chronic) rectosigmoiditis
0.985 0.015 0.000
K60 Fissure and fistula of anal and rectal regions
0.000 0.016 0.984
I47.1 Supraventricular tachycardia
0.000 0.017 0.983
K82 Other diseases of gallbladder
0.000 0.017 0.983
K50-K52 Noninfective enteritis and colitis
0.005 0.018 0.977
K60.2 Anal fissure, unspecified
0.000 0.018 0.982
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.018 0.982
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.018 0.982
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.020 0.980
K82.8 Other specified diseases of gallbladder
0.000 0.021 0.979
I20.9 Angina pectoris, unspecified
0.000 0.021 0.979
H43-H45 Disorders of vitreous body and globe
0.000 0.022 0.978
E11.3 With ophthalmic complications
0.000 0.023 0.977
K74 Fibrosis and cirrhosis of liver
0.000 0.025 0.975
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.028 0.972
H43 Disorders of vitreous body
0.000 0.028 0.972
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.029 0.971
I25.2 Old myocardial infarction
0.000 0.031 0.969
H40-H42 Glaucoma
0.000 0.032 0.968
J45 Asthma
0.000 0.039 0.961
E10.5 With peripheral circulatory complications
0.000 0.040 0.960
I24 Other acute ischaemic heart diseases
0.000 0.041 0.959
K74.3 Primary biliary cirrhosis
0.000 0.041 0.959
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.042 0.958
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.045 0.955
J40-J47 Chronic lower respiratory diseases
0.000 0.049 0.951
E14.9 Without complications
0.000 0.050 0.950
H40 Glaucoma
0.000 0.052 0.948
H40.9 Glaucoma, unspecified
0.000 0.053 0.947
Chapter X Diseases of the respiratory system
0.000 0.054 0.946
M07 Psoriatic and enteropathic arthropathies
0.000 0.058 0.942
K52 Other non-infective gastro-enteritis and colitis
0.001 0.063 0.937
I31 Other diseases of pericardium
0.000 0.070 0.930
H34 Retinal vascular occlusions
0.000 0.070 0.930
H43.3 Other vitreous opacities
0.000 0.071 0.929
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.073 0.927
K51.8 Other ulcerative colitis
0.926 0.074 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.076 0.924
H43.8 Other disorders of vitreous body
0.000 0.076 0.924
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.082 0.918
I21 Acute myocardial infarction
0.000 0.082 0.918
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.083 0.917
I46 Cardiac arrest
0.000 0.085 0.915
K60.0 Acute anal fissure
0.000 0.087 0.913
E11.2 With renal complications
0.000 0.089 0.911
E07 Other disorders of thyroid
0.000 0.090 0.910
I25.5 Ischaemic cardiomyopathy
0.000 0.092 0.908
G37.8 Other specified demyelinating diseases of central nervous system
0.907 0.093 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.094 0.906
K51.2 Ulcerative (chronic) proctitis
0.904 0.096 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.096 0.904
I47.2 Ventricular tachycardia
0.000 0.097 0.903
E10.2 With renal complications
0.000 0.098 0.902
K55 Vascular disorders of intestine
0.000 0.098 0.902
M07.3 Other psoriatic arthropathies
0.000 0.099 0.901
K81 Cholecystitis
0.000 0.102 0.898
I21.9 Acute myocardial infarction, unspecified
0.000 0.103 0.897
E83 Disorders of mineral metabolism
0.859 0.104 0.037
K50 Crohn's disease [regional enteritis]
0.000 0.108 0.891
I31.3 Pericardial effusion (noninflammatory)
0.000 0.114 0.886
J95-J99 Other diseases of the respiratory system
0.000 0.116 0.884
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.122 0.878
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.129 0.871
J44 Other chronic obstructive pulmonary disease
0.000 0.129 0.871
I20.1 Angina pectoris with documented spasm
0.000 0.129 0.871
E03.8 Other specified hypothyroidism
0.000 0.130 0.870
K82.1 Hydrops of gallbladder
0.000 0.131 0.869
E05.9 Thyrotoxicosis, unspecified
0.000 0.135 0.865
E11.5 With peripheral circulatory complications
0.000 0.137 0.863
K75 Other inflammatory liver diseases
0.000 0.137 0.863
I46.9 Cardiac arrest, unspecified
0.000 0.137 0.863
E11.1 With ketoacidosis
0.000 0.139 0.861
K63 Other diseases of intestine
0.000 0.140 0.860
E07.9 Disorder of thyroid, unspecified
0.000 0.145 0.855
E13 Other specified diabetes mellitus
0.000 0.146 0.854
K55.2 Angiodysplasia of colon
0.000 0.146 0.854
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.146 0.854
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.152 0.848
K81.1 Chronic cholecystitis
0.000 0.154 0.846
K60.5 Anorectal fistula
0.000 0.159 0.841
M65-M68 Disorders of synovium and tendon
0.000 0.164 0.836
M06.4 Inflammatory polyarthropathy
0.000 0.165 0.835
K58 Irritable bowel syndrome
0.000 0.166 0.834
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.168 0.832
K74.6 Other and unspecified cirrhosis of liver
0.000 0.168 0.832
H34.2 Other retinal artery occlusions
0.000 0.173 0.827
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.174 0.826
K81.9 Cholecystitis, unspecified
0.000 0.176 0.824
K63.9 Disease of intestine, unspecified
0.000 0.176 0.824
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.177 0.823
J43 Emphysema
0.000 0.179 0.821
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.180 0.820
M06.3 Rheumatoid nodule
0.000 0.180 0.820
I15 Secondary hypertension
0.000 0.183 0.817
E06 Thyroiditis
0.000 0.184 0.816
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.187 0.813
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.188 0.812
K72.9 Hepatic failure, unspecified
0.000 0.188 0.812
I12 Hypertensive renal disease
0.000 0.194 0.806
K51.5 Mucosal proctocolitis
0.806 0.194 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.196 0.804
E83.3 Disorders of phosphorus metabolism
0.794 0.197 0.010
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.197 0.803
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.200 0.800
K52.1 Toxic gastro-enteritis and colitis
0.000 0.200 0.799
K80 Cholelithiasis
0.000 0.204 0.796
J98 Other respiratory disorders
0.000 0.204 0.796
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.205 0.795
E11.0 With coma
0.000 0.205 0.795
I35.8 Other aortic valve disorders
0.000 0.206 0.793
H34.8 Other retinal vascular occlusions
0.000 0.211 0.789
L43.8 Other lichen planus
0.000 0.211 0.789
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.211 0.788
I45 Other conduction disorders
0.000 0.212 0.788
K50.8 Other Crohn's disease
0.000 0.213 0.787
K55.8 Other vascular disorders of intestine
0.000 0.213 0.787
J86 Pyothorax
0.000 0.214 0.786
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.215 0.785
H43.9 Disorder of vitreous body, unspecified
0.000 0.216 0.784
K74.5 Biliary cirrhosis, unspecified
0.000 0.218 0.782
M65 Synovitis and tenosynovitis
0.000 0.220 0.780
K75.4 Autoimmune hepatitis
0.000 0.220 0.780
H40.1 Primary open-angle glaucoma
0.000 0.221 0.779
I47.0 Reentry ventricular arrhythmia
0.000 0.222 0.778
I44 Atrioventricular and left bundle-branch block
0.000 0.225 0.775
J46 Status asthmaticus
0.000 0.230 0.770
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.231 0.769
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.231 0.769
I51 Complications and ill-defined descriptions of heart disease
0.000 0.231 0.769
I25.4 Coronary artery aneurysm
0.000 0.233 0.767
K73 Chronic hepatitis, not elsewhere classified
0.000 0.235 0.765
K50.9 Crohn's disease, unspecified
0.000 0.236 0.764
E11.6 With other specified complications
0.000 0.236 0.764
M06.0 Seronegative rheumatoid arthritis
0.000 0.237 0.763
M11 Other crystal arthropathies
0.000 0.237 0.763
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.754 0.246 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.250 0.750
E40-E46 Malnutrition
0.000 0.250 0.750
E13.9 Without complications
0.000 0.251 0.749
L40.8 Other psoriasis
0.000 0.251 0.749
H30 Chorioretinal inflammation
0.000 0.252 0.748
K72.0 Acute and subacute hepatic failure
0.000 0.252 0.747
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.255 0.745
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.255 0.745
I25.3 Aneurysm of heart
0.000 0.257 0.743
J98.4 Other disorders of lung
0.000 0.261 0.739
E74 Other disorders of carbohydrate metabolism
0.000 0.261 0.739
I23 Certain current complications following acute myocardial infarction
0.000 0.263 0.737
E88 Other metabolic disorders
0.000 0.263 0.737
K82.3 Fistula of gallbladder
0.000 0.263 0.737
K63.3 Ulcer of intestine
0.000 0.265 0.735
K60.4 Rectal fistula
0.000 0.265 0.735
I51.8 Other ill-defined heart diseases
0.000 0.268 0.732
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.274 0.726
K50.0 Crohn's disease of small intestine
0.000 0.277 0.723
L40.0 Psoriasis vulgaris
0.000 0.280 0.720
M14 Arthropathies in other diseases classified elsewhere
0.000 0.281 0.719
I30 Acute pericarditis
0.000 0.281 0.719
E83.5 Disorders of calcium metabolism
0.714 0.283 0.003
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
I52 Other heart disorders in diseases classified elsewhere
0.000 0.283 0.716
I48 Atrial fibrillation and flutter
0.000 0.283 0.716
I41 Myocarditis in diseases classified elsewhere
0.000 0.283 0.716
I40 Acute myocarditis
0.000 0.283 0.716
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.283 0.716
I32 Pericarditis in diseases classified elsewhere
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.716
E16.3 Increased secretion of glucagon
0.000 0.283 0.716
E16.1 Other hypoglycaemia
0.000 0.283 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
L43.3 Subacute (active) lichen planus
0.000 0.284 0.716
L43.2 Lichenoid drug reaction
0.000 0.284 0.716
L43.1 Bullous lichen planus
0.000 0.284 0.716
L43.0 Hypertrophic lichen planus
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
E14.8 With unspecified complications
0.000 0.284 0.715
E14.7 With multiple complications
0.000 0.284 0.715
E14.6 With other specified complications
0.000 0.284 0.715
E14.5 With peripheral circulatory complications
0.000 0.284 0.715
E14.4 With neurological complications
0.000 0.284 0.715
E14.2 Withrenal complications
0.000 0.284 0.715
E14.1 With ketoacidosis
0.000 0.284 0.715
E14.0 With coma
0.000 0.284 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
G36 Other acute disseminated demyelination
0.715 0.285 0.000
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
H43.1 Vitreous haemorrhage
0.000 0.288 0.712
M05.8 Other seropositive rheumatoid arthritis
0.000 0.288 0.711
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.288 0.711
M05.2 Rheumatoid vasculitis
0.000 0.288 0.711
M05.1 Rheumatoid lung disease
0.000 0.288 0.711
M05.0 Felty's syndrome
0.000 0.288 0.711
E83.9 Disorder of mineral metabolism, unspecified
0.689 0.288 0.022
E78.2 Mixed hyperlipidaemia
0.000 0.290 0.710
E78.6 Lipoprotein deficiency
0.000 0.290 0.710
E78.3 Hyperchylomicronaemia
0.000 0.290 0.710
K51.4 Pseudopolyposis of colon
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.000 0.291 0.709
E76 Disorders of glycosaminoglycan metabolism
0.000 0.291 0.709
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.291 0.709
E72 Other disorders of amino-acid metabolism
0.000 0.291 0.709
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.291 0.709
E70 Disorders of aromatic amino-acid metabolism
0.000 0.291 0.709
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.291 0.709
E06.3 Autoimmune thyroiditis
0.000 0.291 0.709
K51.1 Ulcerative (chronic) ileocolitis
0.708 0.291 0.000
K82.9 Disease of gallbladder, unspecified
0.000 0.292 0.708
K77 Liver disorders in diseases classified elsewhere
0.000 0.292 0.708
K71 Toxic liver disease
0.000 0.292 0.708
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.292 0.708
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.292 0.708
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.292 0.708
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.292 0.708
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.292 0.708
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.292 0.708
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.292 0.708
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.292 0.708
K51.0 Ulcerative (chronic) enterocolitis
0.708 0.292 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.292 0.708
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.293 0.706
Chapter VIII Diseases of the ear and mastoid process
0.000 0.295 0.705
K90.9 Intestinal malabsorption, unspecified
0.000 0.296 0.704
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.297 0.703
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.298 0.702
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.299 0.701
I11 Hypertensive heart disease
0.000 0.300 0.700
K74.4 Secondary biliary cirrhosis
0.000 0.301 0.699
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.301 0.699
K74.1 Hepatic sclerosis
0.000 0.301 0.699
K55.1 Chronic vascular disorders of intestine
0.000 0.303 0.697
H43.2 Crystalline deposits in vitreous body
0.000 0.303 0.697
H43.0 Vitreous prolapse
0.000 0.303 0.697
H34.1 Central retinal artery occlusion
0.000 0.304 0.696
K63.2 Fistula of intestine
0.000 0.305 0.695
H42 Glaucoma in diseases classified elsewhere
0.000 0.306 0.694
E78.1 Pure hyperglyceridaemia
0.000 0.307 0.693
J86.9 Pyothorax without fistula
0.000 0.307 0.693
I44.7 Left bundle-branch block, unspecified
0.000 0.307 0.693
M06.34 Rheumatoid nodule (Hand)
0.000 0.309 0.691
I31.9 Disease of pericardium, unspecified
0.000 0.309 0.691
I45.5 Other specified heart block
0.000 0.309 0.691
E79 Disorders of purine and pyrimidine metabolism
0.000 0.310 0.690
J45.8 Mixed asthma
0.000 0.311 0.689
J45.1 Nonallergic asthma
0.000 0.311 0.689
K63.4 Enteroptosis
0.000 0.311 0.689
E11.8 With unspecified complications
0.000 0.313 0.687
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.002 0.315 0.684
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.315 0.685
I05-I09 Chronic rheumatic heart diseases
0.000 0.315 0.685
E78.8 Other disorders of lipoprotein metabolism
0.000 0.316 0.684
J41 Simple and mucopurulent chronic bronchitis
0.000 0.318 0.682
I44.3 Other and unspecified atrioventricular block
0.000 0.318 0.682
I45.2 Bifascicular block
0.000 0.320 0.680
H40.6 Glaucoma secondary to drugs
0.000 0.320 0.679
H40.4 Glaucoma secondary to eye inflammation
0.000 0.320 0.679
H40.3 Glaucoma secondary to eye trauma
0.000 0.320 0.679
E78.4 Other hyperlipidaemia
0.000 0.322 0.678
J86.0 Pyothorax with fistula
0.000 0.322 0.678
K82.2 Perforation of gallbladder
0.000 0.323 0.677
E11.4 With neurological complications
0.000 0.323 0.677
E84 Cystic fibrosis
0.000 0.324 0.675
M07.6 Other enteropathic arthropathies
0.000 0.324 0.675
M07.5 Arthropathy in ulcerative colitis
0.000 0.324 0.675
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.324 0.675
M07.2 Psoriatic spondylitis
0.000 0.324 0.675
M07.1 Arthritis mutilans
0.000 0.324 0.675
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.324 0.675
L42 Pityriasis rosea
0.000 0.324 0.675
J43.2 Centrilobular emphysema
0.000 0.325 0.675
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.325 0.675
I12.9 Hypertensive renal disease without renal failure
0.000 0.326 0.674
J43.9 Emphysema, unspecified
0.000 0.327 0.673
I37 Pulmonary valve disorders
0.000 0.327 0.673
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.332 0.668
I15.1 Hypertension secondary to other renal disorders
0.000 0.333 0.667
I31.8 Other specified diseases of pericardium
0.000 0.333 0.667
I31.2 Haemopericardium, not elsewhere classified
0.000 0.333 0.667
I31.0 Chronic adhesive pericarditis
0.000 0.333 0.667
H34.9 Retinal vascular occlusion, unspecified
0.000 0.333 0.666
H34.0 Transient retinal artery occlusion
0.000 0.333 0.666
Chapter VI Diseases of the nervous system
0.661 0.335 0.004
K90.8 Other intestinal malabsorption
0.000 0.336 0.663
K82.0 Obstruction of gallbladder
0.000 0.338 0.662
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.338 0.662
K52.3 Indeterminate colitis
0.001 0.340 0.659
I36 Nonrheumatic tricuspid valve disorders
0.000 0.342 0.658
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.342 0.658
J98.6 Disorders of diaphragm
0.000 0.343 0.657
I46.1 Sudden cardiac death, so described
0.000 0.344 0.656
M12 Other specific arthropathies
0.000 0.344 0.655
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.345 0.655
E07.1 Dyshormogenetic goitre
0.000 0.347 0.652
E07.0 Hypersecretion of calcitonin
0.000 0.347 0.652
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.349 0.651
K72.1 Chronic hepatic failure
0.000 0.350 0.650
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.350 0.650
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.001 0.351 0.649
E05.5 Thyroid crisis or storm
0.000 0.352 0.648
E05.4 Thyrotoxicosis factitia
0.000 0.352 0.648
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.352 0.648
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.352 0.648
M07.38 Other psoriatic arthropathies (Other)
0.000 0.354 0.646
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.354 0.646
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.354 0.646
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.354 0.646
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.354 0.646
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.354 0.646
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.354 0.646
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.354 0.646
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.354 0.646
M45-M49 Spondylopathies
0.000 0.354 0.646
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.357 0.643
E83.8 Other disorders of mineral metabolism
0.616 0.358 0.026
E83.2 Disorders of zinc metabolism
0.616 0.358 0.026
E83.0 Disorders of copper metabolism
0.616 0.358 0.026
G80-G83 Cerebral palsy and other paralytic syndromes
0.639 0.360 0.001
K75.0 Abscess of liver
0.000 0.362 0.638
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.362 0.638
M70-M79 Other soft tissue disorders
0.000 0.362 0.638
J96 Respiratory failure, not elsewhere classified
0.000 0.366 0.634
I21.4 Acute subendocardial myocardial infarction
0.000 0.368 0.632
I22.8 Subsequent myocardial infarction of other sites
0.000 0.369 0.630
M86-M90 Other osteopathies
0.000 0.371 0.629
E73 Lactose intolerance
0.000 0.373 0.627
H65-H75 Diseases of middle ear and mastoid
0.000 0.373 0.627
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.374 0.626
K75.8 Other specified inflammatory liver diseases
0.000 0.374 0.625
M45 Ankylosing spondylitis
0.000 0.377 0.623
K80.8 Other cholelithiasis
0.000 0.379 0.621
E89.2 Postprocedural hypoparathyroidism
0.000 0.380 0.619
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.381 0.619
K75.2 Nonspecific reactive hepatitis
0.000 0.381 0.619
K75.1 Phlebitis of portal vein
0.000 0.381 0.619
I24.1 Dressler's syndrome
0.000 0.381 0.619
G81 Hemiplegia
0.617 0.383 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.384 0.616
I15.9 Seconday hypertension, unspecified
0.000 0.384 0.616
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.387 0.613
I46.0 Cardiac arrest with successful resuscitation
0.000 0.387 0.613
E13.8 With unspecified complications
0.000 0.388 0.612
E13.7 With multiple complications
0.000 0.388 0.612
E13.6 With other specified complications
0.000 0.388 0.612
E13.5 With peripheral circulatory complications
0.000 0.388 0.612
E13.4 With neurological complications
0.000 0.388 0.612
E13.3 With ophthalmic complications
0.000 0.388 0.612
E13.2 With renal complications
0.000 0.388 0.612
E13.1 With ketoacidosis
0.000 0.388 0.612
E13.0 With coma
0.000 0.388 0.612
H60-H62 Diseases of external ear
0.000 0.388 0.612
J95.8 Other postprocedural respiratory disorders
0.000 0.388 0.612
K60.1 Chronic anal fissure
0.000 0.390 0.610
E89.3 Postprocedural hypopituitarism
0.000 0.390 0.610
E07.8 Other specified disorders of thyroid
0.000 0.391 0.609
H40.5 Glaucoma secondary to other eye disorders
0.000 0.394 0.606
J42 Unspecified chronic bronchitis
0.000 0.394 0.606
I31.1 Chronic constrictive pericarditis
0.000 0.398 0.602
G81.9 Hemiplegia, unspecified
0.601 0.399 0.000
I45.8 Other specified conduction disorders
0.000 0.399 0.601
H71 Cholesteatoma of middle ear
0.000 0.400 0.600
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.400 0.599
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.401 0.599
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.401 0.599
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.401 0.599
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.401 0.599
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.401 0.599
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.401 0.599
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.401 0.599
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.401 0.599
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.401 0.599
M11.2 Other chondrocalcinosis
0.000 0.406 0.594
I45.1 Other and unspecified right bundle-branch block
0.000 0.409 0.591
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.410 0.589
J43.8 Other emphysema
0.000 0.411 0.589
J43.1 Panlobular emphysema
0.000 0.411 0.589
J43.0 MacLeod's syndrome
0.000 0.411 0.589
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.411 0.589
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.412 0.588
M06.38 Rheumatoid nodule (Other)
0.000 0.412 0.588
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.412 0.588
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.412 0.588
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.412 0.588
M06.33 Rheumatoid nodule (Forearm)
0.000 0.412 0.588
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.412 0.588
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.412 0.588
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.412 0.588
E05.8 Other thyrotoxicosis
0.000 0.413 0.587
G30-G32 Other degenerative diseases of the nervous system
0.585 0.413 0.002
I15.8 Other secondary hypertension
0.000 0.414 0.586
I15.2 Hypertension secondary to endocrine disorders
0.000 0.414 0.586
I15.0 Renovascular hypertension
0.000 0.414 0.586
L10-L14 Bullous disorders
0.000 0.414 0.585
I44.0 Atrioventricular block, first degree
0.000 0.414 0.586
E06.5 Other chronic thyroiditis
0.000 0.415 0.585
E06.4 Drug-induced thyroiditis
0.000 0.415 0.585

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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