TreeWAS – Variant ID: rs3134745

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
L40 Psoriasis	0.000	0.002	0.998
E10.1 With ketoacidosis	0.996	0.004	0.000
L40.5 Arthropathic psoriasis	0.000	0.005	0.995
E14 Unspecified diabetes mellitus	0.992	0.008	0.000
M35.0 Sicca syndrome [Sjogren]	0.990	0.010	0.000
E27 Other disorders of adrenal gland	0.988	0.012	0.000
D64.9 Anaemia, unspecified	0.986	0.014	0.000
N40 Hyperplasia of prostate	0.000	0.014	0.986
E27.1 Primary adrenocortical insufficiency	0.984	0.016	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.978	0.022	0.000
E14.3 With ophthalmic complications	0.976	0.024	0.000
E16 Other disorders of pancreatic internal secretion	0.962	0.038	0.000
N40-N51 Diseases of male genital organs	0.000	0.040	0.960
N42 Other disorders of prostate	0.000	0.041	0.959
D64 Other anaemias	0.958	0.042	0.000
N42.8 Other specified disorders of prostate	0.000	0.051	0.949
D60-D64 Aplastic and other anaemias	0.944	0.056	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.939	0.061	0.000
L40.0 Psoriasis vulgaris	0.000	0.061	0.939
D61 Other aplastic anaemias	0.938	0.062	0.000
E16.2 Hypoglycaemia, unspecified	0.933	0.067	0.000
D61.9 Aplastic anaemia, unspecified	0.933	0.067	0.000
E07 Other disorders of thyroid	0.927	0.073	0.000
E21.3 Hyperparathyroidism, unspecified	0.920	0.080	0.000
E10.2 With renal complications	0.908	0.092	0.000
E10.4 With neurological complications	0.892	0.108	0.000
E24 Cushing's syndrome	0.891	0.109	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.118	0.882
E10.0 With coma	0.878	0.122	0.000
E23 Hypofunction and other disorders of pituitary gland	0.876	0.124	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.874	0.126	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.864	0.136	0.000
K90 Intestinal malabsorption	0.849	0.151	0.000
E07.9 Disorder of thyroid, unspecified	0.847	0.153	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.844	0.156	0.000
E23.2 Diabetes insipidus	0.841	0.159	0.000
N42.2 Atrophy of prostate	0.000	0.162	0.838
E03.8 Other specified hypothyroidism	0.829	0.171	0.000
E10.6 With other specified complications	0.829	0.171	0.000
E31 Polyglandular dysfunction	0.819	0.181	0.000
E28 Ovarian dysfunction	0.811	0.189	0.000
E14.6 With other specified complications	0.806	0.194	0.000
E14.1 With ketoacidosis	0.798	0.202	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.203	0.797
N41 Inflammatory diseases of prostate	0.000	0.207	0.793
K90.9 Intestinal malabsorption, unspecified	0.772	0.228	0.000
E10.8 With unspecified complications	0.771	0.229	0.000
E20 Hypoparathyroidism	0.769	0.231	0.000
E24.2 Drug-induced Cushing's syndrome	0.769	0.231	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.235	0.765
E14.8 With unspecified complications	0.760	0.240	0.000
N48 Other disorders of penis	0.000	0.241	0.759
D62 Acute posthaemorrhagic anaemia	0.757	0.243	0.000
E14.5 With peripheral circulatory complications	0.757	0.243	0.000
E07.8 Other specified disorders of thyroid	0.753	0.247	0.000
E10.7 With multiple complications	0.749	0.251	0.000
N44 Torsion of testis	0.000	0.253	0.747
K75.4 Autoimmune hepatitis	0.737	0.263	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.734	0.266	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.730	0.270	0.000
L40.8 Other psoriasis	0.000	0.272	0.728
K75 Other inflammatory liver diseases	0.727	0.273	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.727	0.273	0.000
E29 Testicular dysfunction	0.721	0.279	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
L40.4 Guttate psoriasis	0.000	0.285	0.715
L40.2 Acrodermatitis continua	0.000	0.285	0.715
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.714	0.286	0.000
E14.4 With neurological complications	0.714	0.286	0.000
E10.5 With peripheral circulatory complications	0.713	0.287	0.000
E14.7 With multiple complications	0.711	0.289	0.000
E14.0 With coma	0.711	0.289	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.290	0.710
N48.1 Balanoposthitis	0.000	0.291	0.709
E27.5 Adrenomedullary hyperfunction	0.708	0.292	0.000
E27.0 Other adrenocortical overactivity	0.708	0.292	0.000
E06 Thyroiditis	0.707	0.293	0.000
E14.2 Withrenal complications	0.704	0.296	0.000
E15 Nondiabetic hypoglycaemic coma	0.701	0.299	0.000
E24.0 Pituitary-dependent Cushing's disease	0.699	0.301	0.000
N48.4 Impotence of organic origin	0.000	0.301	0.699
D61.1 Drug-induced aplastic anaemia	0.694	0.306	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.310	0.690
E31.0 Autoimmune polyglandular failure	0.690	0.310	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.690	0.310	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.690	0.310	0.000
E16.4 Abnormal secretion of gastrin	0.690	0.310	0.000
E16.3 Increased secretion of glucagon	0.690	0.310	0.000
N45 Orchitis and epididymitis	0.000	0.312	0.688
D64.4 Congenital dyserythropoietic anaemia	0.687	0.313	0.000
D64.3 Other sideroblastic anaemias	0.687	0.313	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.687	0.313	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.687	0.313	0.000
D64.0 Hereditary sideroblastic anaemia	0.687	0.313	0.000
D61.0 Constitutional aplastic anaemia	0.683	0.317	0.000
K70-K77 Diseases of liver	0.681	0.319	0.000
E23.6 Other disorders of pituitary gland	0.679	0.321	0.000
E16.1 Other hypoglycaemia	0.676	0.324	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.675	0.325	0.000
K75.8 Other specified inflammatory liver diseases	0.674	0.326	0.000
K73 Chronic hepatitis, not elsewhere classified	0.674	0.326	0.000
E21.4 Other specified disorders of parathyroid gland	0.673	0.327	0.000
E21.2 Other hyperparathyroidism	0.673	0.327	0.000
D61.8 Other specified aplastic anaemias	0.672	0.328	0.000
D61.3 Idiopathic aplastic anaemia	0.672	0.328	0.000
D61.2 Aplastic anaemia due to other external agents	0.672	0.328	0.000
L40.1 Generalised pustular psoriasis	0.000	0.333	0.667
E14.9 Without complications	0.666	0.334	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.665	0.335	0.000
E07.1 Dyshormogenetic goitre	0.664	0.336	0.000
E07.0 Hypersecretion of calcitonin	0.664	0.336	0.000
E24.8 Other Cushing's syndrome	0.661	0.338	0.000
E24.9 Cushing's syndrome, unspecified	0.659	0.341	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.653	0.347	0.000
E25 Adrenogenital disorders	0.653	0.347	0.000
N46 Male infertility	0.000	0.348	0.652
N42.3 Dysplasia of prostate	0.000	0.348	0.651
K73.9 Chronic hepatitis, unspecified	0.648	0.352	0.000
E27.9 Disorder of adrenal gland, unspecified	0.646	0.354	0.000
E28.3 Primary ovarian failure	0.640	0.360	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.639	0.361	0.000
E24.3 Ectopic ACTH syndrome	0.639	0.361	0.000
E24.1 Nelson's syndrome	0.639	0.361	0.000
E40-E46 Malnutrition	0.635	0.365	0.000
K75.0 Abscess of liver	0.633	0.367	0.000
N42.0 Calculus of prostate	0.000	0.367	0.632
I77 Other disorders of arteries and arterioles	0.632	0.368	0.000
E28.2 Polycystic ovarian syndrome	0.630	0.370	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.630	0.370	0.000
E13 Other specified diabetes mellitus	0.629	0.370	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.628	0.372	0.000
E23.1 Drug-induced hypopituitarism	0.628	0.372	0.000
N43 Hydrocele and spermatocele	0.000	0.373	0.627
I70-I79 Diseases of arteries, arterioles and capillaries	0.626	0.374	0.000
I77.1 Stricture of artery	0.620	0.380	0.000
I74 Arterial embolism and thrombosis	0.620	0.380	0.000
E27.2 Addisonian crisis	0.615	0.385	0.000
K90.3 Pancreatic steatorrhoea	0.608	0.391	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.608	0.391	0.000
K90.1 Tropical sprue	0.608	0.391	0.000
I73 Other peripheral vascular diseases	0.608	0.392	0.000
E06.3 Autoimmune thyroiditis	0.607	0.393	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.606	0.394	0.000
E20.9 Hypoparathyroidism, unspecified	0.604	0.396	0.000
I73.0 Raynaud's syndrome	0.600	0.400	0.000
K90.8 Other intestinal malabsorption	0.593	0.407	0.000
E31.9 Polyglandular dysfunction, unspecified	0.587	0.413	0.000
E31.8 Other polyglandular dysfunction	0.587	0.413	0.000
E31.1 Polyglandular hyperfunction	0.587	0.413	0.000
I77.6 Arteritis, unspecified	0.587	0.413	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.584	0.416	0.000
I74.8 Embolism and thrombosis of other arteries	0.582	0.418	0.000
K72 Hepatic failure, not elsewhere classified	0.582	0.418	0.000
E28.9 Ovarian dysfunction, unspecified	0.581	0.418	0.000
E28.8 Other ovarian dysfunction	0.581	0.418	0.000
E28.1 Androgen excess	0.581	0.418	0.000
E28.0 Oestrogen excess	0.581	0.418	0.000
N48.3 Priapism	0.000	0.420	0.580
I77.9 Disorder of arteries and arterioles, unspecified	0.577	0.423	0.000
D64.8 Other specified anaemias	0.575	0.425	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.428	0.572
N50 Other disorders of male genital organs	0.000	0.428	0.572
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.572	0.428	0.000
N41.3 Prostatocystitis	0.000	0.431	0.569
N41.2 Abscess of prostate	0.000	0.431	0.569
E23.7 Disorder of pituitary gland, unspecified	0.568	0.432	0.000
I74.5 Embolism and thrombosis of iliac artery	0.568	0.432	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.568	0.432	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.433	0.567
E05.8 Other thyrotoxicosis	0.566	0.433	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.439	0.561
E26 Hyperaldosteronism	0.555	0.445	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.448	0.552
E20.8 Other hypoparathyroidism	0.551	0.448	0.000
E20.1 Pseudohypoparathyroidism	0.551	0.448	0.000
E20.0 Idiopathic hypoparathyroidism	0.551	0.448	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.550	0.450	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.547	0.453	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.545	0.455	0.000
N48.5 Ulcer of penis	0.000	0.469	0.531
D80-D89 Certain disorders involving the immune mechanism	0.530	0.470	0.000
E22 Hyperfunction of pituitary gland	0.528	0.471	0.000
D60.8 Other acquired pure red cell aplasias	0.526	0.473	0.000
D60.1 Transient acquired pure red cell aplasia	0.526	0.473	0.000
D60.0 Chronic acquired pure red cell aplasia	0.526	0.473	0.000
N48.9 Disorder of penis, unspecified	0.000	0.478	0.522
E29.1 Testicular hypofunction	0.522	0.478	0.000
K75.2 Nonspecific reactive hepatitis	0.521	0.479	0.000
K75.1 Phlebitis of portal vein	0.521	0.479	0.000
E29.9 Testicular dysfunction, unspecified	0.517	0.483	0.000
E29.8 Other testicular dysfunction	0.517	0.483	0.000
E29.0 Testicular hyperfunction	0.517	0.483	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E30.9 Disorder of puberty, unspecified	0.513	0.486	0.000
E30.8 Other disorders of puberty	0.513	0.486	0.000
E30.1 Precocious puberty	0.513	0.486	0.000
E30.0 Delayed puberty	0.513	0.486	0.000
E32.9 Disease of thymus, unspecified	0.513	0.486	0.000
E32.8 Other diseases of thymus	0.513	0.486	0.000
E32.1 Abscess of thymus	0.513	0.486	0.000
E32.0 Persistent hyperplasia of thymus	0.513	0.486	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.513	0.486	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.513	0.486	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.513	0.486	0.000
D80 Immunodeficiency with predominantly antibody defects	0.510	0.490	0.000
E06.4 Drug-induced thyroiditis	0.507	0.493	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.507	0.493	0.000
E06.1 Subacute thyroiditis	0.507	0.493	0.000
E06.0 Acute thyroiditis	0.507	0.493	0.000
K72.0 Acute and subacute hepatic failure	0.507	0.493	0.000
N43.2 Other hydrocele	0.000	0.497	0.502
K74 Fibrosis and cirrhosis of liver	0.499	0.501	0.000
N51.2 Balanitis in diseases classified elsewhere	0.000	0.503	0.497
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.496	0.504	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.000	0.505	0.495
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.000	0.505	0.495
N51.0 Disorders of prostate in diseases classified elsewhere	0.000	0.505	0.495
K77 Liver disorders in diseases classified elsewhere	0.488	0.511	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.486	0.514	0.000
E06.5 Other chronic thyroiditis	0.484	0.515	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.483	0.517	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.483	0.517	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.483	0.517	0.000
E34 Other endocrine disorders	0.483	0.517	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.481	0.519	0.000
D69 Purpura and other haemorrhagic conditions	0.480	0.520	0.000
K71 Toxic liver disease	0.478	0.522	0.000
I77.2 Rupture of artery	0.476	0.524	0.000
E50-E64 Other nutritional deficiencies	0.470	0.529	0.000
K70 Alcoholic liver disease	0.470	0.530	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.469	0.531	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.468	0.531	0.000
E25.9 Adrenogenital disorder, unspecified	0.468	0.532	0.000
E25.8 Other adrenogenital disorders	0.468	0.532	0.000
N50.0 Atrophy of testis	0.000	0.532	0.468
I77.0 Arteriovenous fistula, acquired	0.467	0.533	0.000
D69.6 Thrombocytopenia, unspecified	0.466	0.534	0.000
E13.3 With ophthalmic complications	0.465	0.535	0.000
I71 Aortic aneurysm and dissection	0.463	0.537	0.000
N43.1 Infected hydrocele	0.000	0.542	0.458
E44 Protein-energy malnutrition of moderate and mild degree	0.455	0.544	0.000
E45 Retarded development following protein-energy malnutrition	0.455	0.544	0.000
E43 Unspecified severe protein-energy malnutrition	0.455	0.544	0.000
E42 Marasmic kwashiorkor	0.455	0.544	0.000
E41 Nutritional marasmus	0.455	0.544	0.000
E40 Kwashiorkor	0.455	0.544	0.000
I77.5 Necrosis of artery	0.453	0.547	0.000
I77.4 Coeliac artery compression syndrome	0.453	0.547	0.000
I77.3 Arterial fibromuscular dysplasia	0.453	0.547	0.000
E13.8 With unspecified complications	0.451	0.548	0.000
E13.7 With multiple complications	0.451	0.548	0.000
E13.6 With other specified complications	0.451	0.548	0.000
E13.5 With peripheral circulatory complications	0.451	0.548	0.000
E13.4 With neurological complications	0.451	0.548	0.000
E13.2 With renal complications	0.451	0.548	0.000
E13.1 With ketoacidosis	0.451	0.548	0.000
E13.0 With coma	0.451	0.548	0.000
N43.0 Encysted hydrocele	0.000	0.550	0.450
N50.1 Vascular disorders of male genital organs	0.000	0.552	0.448
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.442	0.558	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.441	0.559	0.000
K72.9 Hepatic failure, unspecified	0.441	0.559	0.000
K70.4 Alcoholic hepatic failure	0.438	0.562	0.000
D83 Common variable immunodeficiency	0.437	0.563	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.435	0.564	0.000
N43.4 Spermatocele	0.000	0.565	0.435
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.433	0.567	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.433	0.567	0.000
D69.4 Other primary thrombocytopenia	0.432	0.568	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.429	0.571	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.426	0.573	0.000
N48.8 Other specified disorders of penis	0.000	0.580	0.420
E27.8 Other specified disorders of adrenal gland	0.419	0.580	0.001
N41.1 Chronic prostatitis	0.000	0.581	0.419
D84 Other immunodeficiencies	0.417	0.583	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.590	0.410
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.590	0.410
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.590	0.410
K74.3 Primary biliary cirrhosis	0.410	0.590	0.000
C85.1 B-cell lymphoma, unspecified	0.409	0.591	0.000
N50.9 Disorder of male genital organs, unspecified	0.000	0.591	0.409
M35 Other systemic involvement of connective tissue	0.407	0.593	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.405	0.595	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.401	0.598	0.000
K72.1 Chronic hepatic failure	0.399	0.600	0.000
E26.8 Other hyperaldosteronism	0.398	0.602	0.000
E26.1 Secondary hyperaldosteronism	0.398	0.602	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.603	0.397
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.396	0.604	0.000
E21.0 Primary hyperparathyroidism	0.393	0.607	0.000
I79.1 Aortitis in diseases classified elsewhere	0.390	0.609	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.390	0.609	0.000
D69.0 Allergic purpura	0.390	0.610	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.387	0.613	0.000
I70 Atherosclerosis	0.387	0.613	0.000
K70.0 Alcoholic fatty liver	0.385	0.615	0.000
D55-D59 Haemolytic anaemias	0.380	0.620	0.000
D81 Combined immunodeficiencies	0.380	0.620	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.379	0.621	0.000
E22.8 Other hyperfunction of pituitary gland	0.379	0.621	0.000
K75.9 Inflammatory liver disease, unspecified	0.378	0.622	0.000
I73.9 Peripheral vascular disease, unspecified	0.377	0.623	0.000
L40-L45 Papulosquamous disorders	0.033	0.624	0.343
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.375	0.625	0.000
D69.2 Other nonthrombocytopenic purpura	0.375	0.625	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.625	0.375
E46 Unspecified protein-energy malnutrition	0.373	0.626	0.000
D83.9 Common variable immunodeficiency, unspecified	0.371	0.629	0.000
K71.0 Toxic liver disease with cholestasis	0.367	0.632	0.000
I77.8 Other specified disorders of arteries and arterioles	0.367	0.633	0.000
I73.8 Other specified peripheral vascular diseases	0.366	0.634	0.000
D69.8 Other specified haemorrhagic conditions	0.366	0.634	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.365	0.634	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.365	0.634	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.365	0.634	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.365	0.634	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.365	0.634	0.000
E51 Thiamine deficiency	0.365	0.635	0.000
E26.9 Hyperaldosteronism, unspecified	0.363	0.637	0.000
K74.6 Other and unspecified cirrhosis of liver	0.358	0.642	0.000
K74.4 Secondary biliary cirrhosis	0.358	0.642	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.358	0.642	0.000
K74.1 Hepatic sclerosis	0.358	0.642	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.357	0.643	0.000
D69.5 Secondary thrombocytopenia	0.354	0.646	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.353	0.647	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.350	0.650	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.350	0.650	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.349	0.651	0.000
D67 Hereditary factor IX deficiency	0.348	0.652	0.000
E34.5 Androgen resistance syndrome	0.346	0.653	0.000
E34.4 Constitutional tall stature	0.346	0.653	0.000
E34.3 Short stature, not elsewhere classified	0.346	0.653	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.346	0.653	0.000
E34.1 Other hypersecretion of intestinal hormones	0.346	0.653	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.345	0.655	0.000
D82 Immunodeficiency associated with other major defects	0.344	0.655	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.344	0.656	0.000
K71.9 Toxic liver disease, unspecified	0.343	0.657	0.000
K71.8 Toxic liver disease with other disorders of liver	0.343	0.657	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.343	0.657	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.343	0.657	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.343	0.657	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.343	0.657	0.000
K71.2 Toxic liver disease with acute hepatitis	0.343	0.657	0.000
E13.9 Without complications	0.342	0.658	0.000
E34.8 Other specified endocrine disorders	0.339	0.661	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.339	0.661	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.337	0.662	0.000
E63 Other nutritional deficiencies	0.337	0.662	0.000
E50 Vitamin A deficiency	0.337	0.662	0.000
E60 Dietary zinc deficiency	0.337	0.662	0.000
E59 Dietary selenium deficiency	0.337	0.662	0.000
E54 Ascorbic acid deficiency	0.337	0.662	0.000
E52 Niacin deficiency [pellagra]	0.337	0.662	0.000
D84.9 Immunodeficiency, unspecified	0.336	0.664	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.335	0.665	0.000
M35.1 Other overlap syndromes	0.334	0.666	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.332	0.668	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.332	0.668	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.332	0.668	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.332	0.668	0.000
D69.1 Qualitative platelet defects	0.329	0.671	0.000
E06.9 Thyroiditis, unspecified	0.329	0.671	0.001
K74.0 Hepatic fibrosis	0.328	0.672	0.000
K74.5 Biliary cirrhosis, unspecified	0.327	0.673	0.000
E44.1 Mild protein-energy malnutrition	0.327	0.673	0.000
E44.0 Moderate protein-energy malnutrition	0.327	0.673	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.326	0.674	0.000
E61 Deficiency of other nutrient elements	0.324	0.676	0.000
D50-D53 Nutritional anaemias	0.320	0.680	0.000
E58 Dietary calcium deficiency	0.318	0.682	0.000
E56 Other vitamin deficiencies	0.317	0.683	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.684	0.315
D83.8 Other common variable immunodeficiencies	0.314	0.686	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.314	0.686	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.314	0.686	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.314	0.686	0.000
E34.9 Endocrine disorder, unspecified	0.312	0.688	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.312	0.688	0.000
M35.7 Hypermobility syndrome	0.311	0.689	0.000
E22.1 Hyperprolactinaemia	0.308	0.692	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.307	0.693	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.306	0.694	0.000
D69.9 Haemorrhagic condition, unspecified	0.304	0.696	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.299	0.701	0.000
D84.8 Other specified immunodeficiencies	0.299	0.701	0.000
D84.1 Defects in the complement system	0.299	0.701	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.299	0.701	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.299	0.701	0.000
N43.3 Hydrocele, unspecified	0.000	0.701	0.299
I70.0 Atherosclerosis of aorta	0.298	0.702	0.000
M35.2 Behcet's disease	0.298	0.702	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.298	0.702	0.000
C91 Lymphoid leukaemia	0.296	0.704	0.000
E26.0 Primary hyperaldosteronism	0.294	0.705	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.292	0.708	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.292	0.708	0.000
M35.5 Multifocal fibrosclerosis	0.292	0.708	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.292	0.708	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.291	0.709	0.000
E51.2 Wernicke's encephalopathy	0.290	0.710	0.000
I71.0 Dissection of aorta [any part]	0.289	0.711	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.286	0.713	0.000
C83.3 Large cell (diffuse)	0.285	0.715	0.000
C85.0 Lymphosarcoma	0.284	0.716	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.284	0.716	0.000
D58 Other hereditary haemolytic anaemias	0.281	0.719	0.000
K90-K93 Other diseases of the digestive system	0.280	0.720	0.000
C81 Hodgkin's disease	0.279	0.721	0.000
D89.3 Immune reconstitution syndrome	0.278	0.722	0.000
I70.9 Generalised and unspecified atherosclerosis	0.278	0.722	0.000
C91.1 Chronic lymphocytic leukaemia	0.277	0.723	0.000
D57 Sickle-cell disorders	0.274	0.726	0.000
I72 Other aneurysm	0.274	0.726	0.000
D89.1 Cryoglobulinaemia	0.273	0.727	0.000
D55 Anaemia due to enzyme disorders	0.273	0.727	0.000
D81.9 Combined immunodeficiency, unspecified	0.272	0.727	0.000
D81.8 Other combined immunodeficiencies	0.272	0.727	0.000
D81.7 Major histocompatibility complex class II deficiency	0.272	0.727	0.000
D81.6 Major histocompatibility complex class I deficiency	0.272	0.727	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.272	0.727	0.000
D81.4 Nezelof's syndrome	0.272	0.727	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.272	0.727	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.272	0.727	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.272	0.727	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.272	0.727	0.000
M35.8 Other specified systemic involvement of connective tissue	0.272	0.728	0.000
E53 Deficiency of other B group vitamins	0.272	0.728	0.000
L41 Parapsoriasis	0.024	0.731	0.246
L45 Papulosquamous disorders in diseases classified elsewhere	0.024	0.731	0.246
D63.8 Anaemia in other chronic diseases classified elsewhere	0.267	0.733	0.000
N41.0 Acute prostatitis	0.000	0.736	0.264
C84 Peripheral and cutaneous T-cell lymphomas	0.264	0.736	0.000
L44 Other papulosquamous disorders	0.024	0.737	0.239
E51.9 Thiamine deficiency, unspecified	0.262	0.738	0.000
E51.8 Other manifestations of thiamine deficiency	0.262	0.738	0.000
E51.1 Beriberi	0.262	0.738	0.000
I70.8 Atherosclerosis of other arteries	0.260	0.740	0.000
L42 Pityriasis rosea	0.022	0.740	0.238
K70.1 Alcoholic hepatitis	0.260	0.740	0.000
H36.0 Diabetic retinopathy	0.259	0.741	0.000
I70.1 Atherosclerosis of renal artery	0.257	0.743	0.000
C88 Malignant immunoproliferative diseases	0.255	0.745	0.000
D59 Acquired haemolytic anaemia	0.255	0.745	0.000
C95 Leukaemia of unspecified cell type	0.253	0.747	0.000
C86 Other specified types of T/NK-cell lymphoma	0.252	0.748	0.000
D56 Thalassaemia	0.251	0.749	0.000
E55 Vitamin D deficiency	0.249	0.751	0.000
D50 Iron deficiency anaemia	0.248	0.752	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.247	0.753	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.247	0.753	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.247	0.753	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.247	0.753	0.000
D82.2 Immunodeficiency with short-limbed stature	0.247	0.753	0.000
D82.0 Wiskott-Aldrich syndrome	0.247	0.753	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations