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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3134926
log Bayes Factor = 56.2858
Chromosome 6   position 32,200,147  (GRCh37) Explore rs3134926 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.007 0.993
M05-M14 Inflammatory polyarthropathies
0.000 0.008 0.992
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.008 0.992
M05 Seropositive rheumatoid arthritis
0.000 0.009 0.991
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.009 0.991
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.010 0.990
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.010 0.990
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.012 0.988
K90.0 Coeliac disease
0.000 0.012 0.988
E03 Other hypothyroidism
0.000 0.017 0.983
E03.9 Hypothyroidism, unspecified
0.000 0.022 0.978
E50-E64 Other nutritional deficiencies
0.000 0.029 0.971
E10.2 With renal complications
0.000 0.032 0.968
J33.0 Polyp of nasal cavity
0.000 0.038 0.962
J33 Nasal polyp
0.000 0.042 0.958
E04 Other non-toxic goitre
0.000 0.042 0.958
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.052 0.948
E20-E35 Disorders of other endocrine glands
0.000 0.059 0.941
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.059 0.941
E14 Unspecified diabetes mellitus
0.000 0.060 0.940
E27 Other disorders of adrenal gland
0.000 0.061 0.939
J33.9 Nasal polyp, unspecified
0.000 0.065 0.935
E27.1 Primary adrenocortical insufficiency
0.000 0.066 0.934
M06.3 Rheumatoid nodule
0.000 0.067 0.933
E05.9 Thyrotoxicosis, unspecified
0.000 0.080 0.920
J30-J39 Other diseases of upper respiratory tract
0.000 0.082 0.918
E16 Other disorders of pancreatic internal secretion
0.000 0.088 0.912
E53 Deficiency of other B group vitamins
0.000 0.092 0.908
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.095 0.905
E14.3 With ophthalmic complications
0.000 0.098 0.902
E16.2 Hypoglycaemia, unspecified
0.000 0.115 0.885
J39 Other diseases of upper respiratory tract
0.000 0.119 0.881
E55 Vitamin D deficiency
0.000 0.121 0.879
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.122 0.878
M06.4 Inflammatory polyarthropathy
0.000 0.124 0.876
E04.9 Non-toxic goitre, unspecified
0.000 0.126 0.874
J32 Chronic sinusitis
0.000 0.132 0.868
E10.0 With coma
0.000 0.133 0.867
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.134 0.866
E04.0 Non-toxic diffuse goitre
0.000 0.135 0.865
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.135 0.865
E06 Thyroiditis
0.000 0.136 0.864
E10.6 With other specified complications
0.000 0.139 0.861
G37 Other demyelinating diseases of central nervous system
0.000 0.139 0.861
E10.4 With neurological complications
0.000 0.144 0.856
L40 Psoriasis
0.000 0.152 0.848
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.156 0.844
M06.0 Seronegative rheumatoid arthritis
0.000 0.157 0.843
J32.9 Chronic sinusitis, unspecified
0.000 0.158 0.842
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.837 0.163 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.173 0.827
E27.8 Other specified disorders of adrenal gland
0.000 0.177 0.823
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.182 0.818
E55.9 Vitamin D deficiency, unspecified
0.000 0.188 0.812
E27.2 Addisonian crisis
0.000 0.191 0.809
J38.4 Oedema of larynx
0.000 0.193 0.807
E53.8 Deficiency of other specified B group vitamins
0.000 0.193 0.807
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.194 0.806
M07 Psoriatic and enteropathic arthropathies
0.000 0.196 0.804
E10.5 With peripheral circulatory complications
0.000 0.199 0.801
E06.3 Autoimmune thyroiditis
0.000 0.202 0.798
Chapter X Diseases of the respiratory system
0.000 0.202 0.798
E53.9 Vitamin B deficiency, unspecified
0.000 0.206 0.794
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.207 0.792
E04.2 Non-toxic multinodular goitre
0.000 0.210 0.790
M06.34 Rheumatoid nodule (Hand)
0.000 0.211 0.789
J20-J22 Other acute lower respiratory infections
0.000 0.217 0.783
J39.8 Other specified diseases of upper respiratory tract
0.000 0.217 0.783
L40.5 Arthropathic psoriasis
0.000 0.219 0.781
J40-J47 Chronic lower respiratory diseases
0.000 0.227 0.773
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.228 0.772
J47 Bronchiectasis
0.000 0.230 0.770
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.235 0.765
E20 Hypoparathyroidism
0.000 0.237 0.763
E61 Deficiency of other nutrient elements
0.000 0.241 0.759
J38.5 Laryngeal spasm
0.000 0.241 0.759
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.248 0.752
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.249 0.751
J20 Acute bronchitis
0.000 0.251 0.749
M12 Other specific arthropathies
0.000 0.252 0.748
J33.8 Other polyp of sinus
0.000 0.259 0.741
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.261 0.739
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.263 0.737
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.264 0.736
E05.8 Other thyrotoxicosis
0.000 0.275 0.725
E11 Non-insulin-dependent diabetes mellitus
0.000 0.276 0.724
J20.9 Acute bronchitis, unspecified
0.000 0.280 0.720
E14.8 With unspecified complications
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.716
M06.1 Adult-onset Still's disease
0.000 0.283 0.716
E14.5 With peripheral circulatory complications
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E70-E90 Metabolic disorders
0.000 0.286 0.714
E10.8 With unspecified complications
0.000 0.287 0.713
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.289 0.711
M08 Juvenile arthritis
0.000 0.289 0.711
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.289 0.711
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.289 0.711
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.289 0.711
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.289 0.711
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.289 0.711
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.289 0.711
M05.8 Other seropositive rheumatoid arthritis
0.000 0.289 0.711
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.289 0.711
M05.2 Rheumatoid vasculitis
0.000 0.289 0.711
M05.1 Rheumatoid lung disease
0.000 0.289 0.711
M05.0 Felty's syndrome
0.000 0.289 0.711
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.291 0.709
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.291 0.709
J39.2 Other diseases of pharynx
0.000 0.292 0.708
M10 Gout
0.000 0.295 0.705
E03.5 Myxoedema coma
0.000 0.295 0.704
E03.4 Atrophy of thyroid (acquired)
0.000 0.295 0.704
E03.3 Postinfectious hypothyroidism
0.000 0.295 0.704
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.295 0.704
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
J44 Other chronic obstructive pulmonary disease
0.000 0.297 0.703
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.304 0.696
E63 Other nutritional deficiencies
0.000 0.304 0.696
E56 Other vitamin deficiencies
0.000 0.304 0.696
E50 Vitamin A deficiency
0.000 0.304 0.696
E60 Dietary zinc deficiency
0.000 0.304 0.696
E59 Dietary selenium deficiency
0.000 0.304 0.696
E54 Ascorbic acid deficiency
0.000 0.304 0.696
E52 Niacin deficiency [pellagra]
0.000 0.304 0.696
M06.8 Other specified rheumatoid arthritis
0.000 0.307 0.693
E24 Cushing's syndrome
0.000 0.309 0.690
E04.8 Other specified non-toxic goitre
0.000 0.313 0.687
E07 Other disorders of thyroid
0.000 0.313 0.687
E86 Volume depletion
0.000 0.316 0.684
J22 Unspecified acute lower respiratory infection
0.000 0.317 0.683
E51 Thiamine deficiency
0.000 0.317 0.683
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.318 0.682
J38.1 Polyp of vocal cord and larynx
0.000 0.319 0.681
J34 Other disorders of nose and nasal sinuses
0.000 0.319 0.681
E15 Nondiabetic hypoglycaemic coma
0.000 0.320 0.680
E25 Adrenogenital disorders
0.000 0.322 0.678
L40.0 Psoriasis vulgaris
0.000 0.323 0.677
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.324 0.676
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.325 0.675
E32 Diseases of thymus
0.000 0.325 0.675
E31 Polyglandular dysfunction
0.000 0.325 0.675
E30 Disorders of puberty, not elsewhere classified
0.000 0.325 0.675
J32.0 Chronic maxillary sinusitis
0.000 0.326 0.674
E14.7 With multiple complications
0.000 0.326 0.674
E14.6 With other specified complications
0.000 0.326 0.674
E14.0 With coma
0.000 0.326 0.674
E27.5 Adrenomedullary hyperfunction
0.000 0.326 0.673
E27.0 Other adrenocortical overactivity
0.000 0.326 0.673
E14.1 With ketoacidosis
0.000 0.328 0.672
J34.3 Hypertrophy of nasal turbinates
0.000 0.330 0.670
M07.3 Other psoriatic arthropathies
0.000 0.331 0.669
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.331 0.669
M06.38 Rheumatoid nodule (Other)
0.000 0.331 0.669
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.331 0.669
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.331 0.669
M06.33 Rheumatoid nodule (Forearm)
0.000 0.331 0.669
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.331 0.669
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.331 0.669
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.334 0.666
E11.3 With ophthalmic complications
0.000 0.335 0.665
E14.9 Without complications
0.000 0.335 0.665
J33.1 Polypoid sinus degeneration
0.000 0.339 0.660
E11.8 With unspecified complications
0.000 0.340 0.660
J37 Chronic laryngitis and laryngotracheitis
0.000 0.340 0.660
G36 Other acute disseminated demyelination
0.000 0.341 0.659
J32.8 Other chronic sinusitis
0.000 0.342 0.658
E61.1 Iron deficiency
0.000 0.344 0.656
J38.7 Other diseases of larynx
0.000 0.344 0.656
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.346 0.654
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.346 0.654
E16.4 Abnormal secretion of gastrin
0.000 0.346 0.654
E16.3 Increased secretion of glucagon
0.000 0.346 0.654
E14.2 Withrenal complications
0.000 0.346 0.653
J38.0 Paralysis of vocal cords and larynx
0.000 0.348 0.652
E53.1 Pyridoxine deficiency
0.000 0.349 0.651
E53.0 Riboflavin deficiency
0.000 0.349 0.651
E40-E46 Malnutrition
0.000 0.356 0.644
E73 Lactose intolerance
0.000 0.357 0.643
E58 Dietary calcium deficiency
0.000 0.362 0.638
E20.9 Hypoparathyroidism, unspecified
0.000 0.364 0.636
J32.4 Chronic pansinusitis
0.000 0.365 0.635
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.365 0.635
E27.9 Disorder of adrenal gland, unspecified
0.000 0.367 0.633
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.368 0.632
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.369 0.631
J39.1 Other abscess of pharynx
0.000 0.369 0.631
E55.0 Rickets, active
0.000 0.370 0.630
J21 Acute bronchiolitis
0.000 0.370 0.630
M14 Arthropathies in other diseases classified elsewhere
0.000 0.371 0.629
E34 Other endocrine disorders
0.000 0.372 0.628
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.372 0.628
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.372 0.628
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.372 0.628
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.372 0.628
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.372 0.628
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.372 0.628
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.372 0.628
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.372 0.628
J38.2 Nodules of vocal cords
0.000 0.380 0.620
E06.4 Drug-induced thyroiditis
0.000 0.380 0.619
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.380 0.619
E06.0 Acute thyroiditis
0.000 0.380 0.619
G37.5 Concentric sclerosis [Balo]
0.000 0.383 0.617
G37.4 Subacute necrotising myelitis
0.000 0.383 0.617
G37.2 Central pontine myelinolysis
0.000 0.383 0.617
G37.1 Central demyelination of corpus callosum
0.000 0.383 0.617
G37.0 Diffuse sclerosis
0.000 0.383 0.617
J32.2 Chronic ethmoidal sinusitis
0.000 0.384 0.616
E06.5 Other chronic thyroiditis
0.000 0.386 0.614
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.391 0.609
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.392 0.608
L40.3 Pustulosis palmaris et plantaris
0.000 0.392 0.608
L40.2 Acrodermatitis continua
0.000 0.392 0.608
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.393 0.607
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.396 0.604
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.396 0.604
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.396 0.604
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.396 0.604
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.396 0.604
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.396 0.604
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.400 0.599
M12.3 Palindromic rheumatism
0.000 0.406 0.594
M10.0 Idiopathic gout
0.000 0.406 0.594
E73.9 Lactose intolerance, unspecified
0.000 0.408 0.592
L40.1 Generalised pustular psoriasis
0.000 0.409 0.590
E06.9 Thyroiditis, unspecified
0.000 0.410 0.589
E16.1 Other hypoglycaemia
0.000 0.416 0.584
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.419 0.581
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.423 0.577
M07.6 Other enteropathic arthropathies
0.000 0.424 0.576
M07.5 Arthropathy in ulcerative colitis
0.000 0.424 0.576
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.424 0.576
M07.2 Psoriatic spondylitis
0.000 0.424 0.576
M07.1 Arthritis mutilans
0.000 0.424 0.576
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.424 0.576
E07.8 Other specified disorders of thyroid
0.000 0.426 0.574
L40-L45 Papulosquamous disorders
0.000 0.427 0.573
M11 Other crystal arthropathies
0.000 0.429 0.571
J20.8 Acute bronchitis due to other specified organisms
0.000 0.436 0.564
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.439 0.561
E14.4 With neurological complications
0.000 0.439 0.561
E24.9 Cushing's syndrome, unspecified
0.000 0.442 0.558
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.445 0.555
E24.0 Pituitary-dependent Cushing's disease
0.000 0.445 0.555
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.447 0.553
J38.6 Stenosis of larynx
0.000 0.447 0.552
J32.3 Chronic sphenoidal sinusitis
0.000 0.449 0.551
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.450 0.550
E06.1 Subacute thyroiditis
0.000 0.452 0.548
J80 Adult respiratory distress syndrome
0.000 0.452 0.548
E20.8 Other hypoparathyroidism
0.000 0.452 0.547
E20.1 Pseudohypoparathyroidism
0.000 0.452 0.547
E20.0 Idiopathic hypoparathyroidism
0.000 0.452 0.547
E61.9 Deficiency of nutrient element, unspecified
0.000 0.455 0.544
E61.8 Deficiency of other specified nutrient elements
0.000 0.455 0.544
E61.7 Deficiency of multiple nutrient elements
0.000 0.455 0.544
E61.6 Vanadium deficiency
0.000 0.455 0.544
E61.5 Molybdenum deficiency
0.000 0.455 0.544
E61.4 Chromium deficiency
0.000 0.455 0.544
E61.3 Manganese deficiency
0.000 0.455 0.544
E61.0 Copper deficiency
0.000 0.455 0.544
J20.7 Acute bronchitis due to echovirus
0.000 0.463 0.537
J20.6 Acute bronchitis due to rhinovirus
0.000 0.463 0.537
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.463 0.537
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.463 0.537
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.463 0.537
J20.2 Acute bronchitis due to streptococcus
0.000 0.463 0.537
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.463 0.537
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.463 0.537
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.464 0.536
M12.5 Traumatic arthropathy
0.000 0.464 0.536
M12.4 Intermittent hydrarthrosis
0.000 0.464 0.536
M12.1 Kaschin-Beck disease
0.000 0.464 0.536
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.464 0.536
L40.4 Guttate psoriasis
0.000 0.465 0.535
E11.0 With coma
0.000 0.465 0.535
E11.1 With ketoacidosis
0.000 0.470 0.530
E79 Disorders of purine and pyrimidine metabolism
0.000 0.473 0.527
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.477 0.523
J43 Emphysema
0.000 0.479 0.521
J21.9 Acute bronchiolitis, unspecified
0.000 0.480 0.520
E78.2 Mixed hyperlipidaemia
0.000 0.481 0.519
E11.7 With multiple complications
0.000 0.481 0.519
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.483 0.517
E03.8 Other specified hypothyroidism
0.000 0.484 0.515
J46 Status asthmaticus
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E89.0 Postprocedural hypothyroidism
0.000 0.487 0.513
E88 Other metabolic disorders
0.000 0.488 0.512
E77 Disorders of glycoprotein metabolism
0.000 0.488 0.512
E76 Disorders of glycosaminoglycan metabolism
0.000 0.488 0.512
E72 Other disorders of amino-acid metabolism
0.000 0.488 0.512
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.488 0.512
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.488 0.512
M08.9 Juvenile arthritis, unspecified
0.000 0.490 0.510
M08.8 Other juvenile arthritis
0.000 0.490 0.510
M08.4 Pauciarticular juvenile arthritis
0.000 0.490 0.510
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.490 0.510
M08.2 Juvenile arthritis with systemic onset
0.000 0.490 0.510
M08.1 Juvenile ankylosing spondylitis
0.000 0.490 0.510
M08.0 Juvenile rheumatoid arthritis
0.000 0.490 0.510
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.490 0.510
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.490 0.510
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.490 0.510
M09.0 Juvenile arthritis in psoriasis
0.000 0.490 0.510
M05.09 Felty's syndrome (Site unspecified)
0.000 0.490 0.510
M05.08 Felty's syndrome (Other)
0.000 0.490 0.510
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.490 0.510
M05.06 Felty's syndrome (Lower leg)
0.000 0.490 0.510
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.490 0.510
M05.04 Felty's syndrome (Hand)
0.000 0.490 0.510
M05.03 Felty's syndrome (Forearm)
0.000 0.490 0.510
M05.02 Felty's syndrome (Upper arm)
0.000 0.490 0.510
M05.01 Felty's syndrome (Shoulder region)
0.000 0.490 0.510
M05.00 Felty's syndrome (Multiple sites)
0.000 0.490 0.510
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.490 0.510
M05.18 Rheumatoid lung disease (Other)
0.000 0.490 0.510
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.490 0.510
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.490 0.510
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.490 0.510
M05.14 Rheumatoid lung disease (Hand)
0.000 0.490 0.510
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.490 0.510
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.490 0.510
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.490 0.510
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.490 0.510
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.490 0.510
M05.28 Rheumatoid vasculitis (Other)
0.000 0.490 0.510
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.490 0.510
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.490 0.510
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.490 0.510
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.490 0.510
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.490 0.510
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.490 0.510
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.490 0.510
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.490 0.510
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.490 0.510
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.490 0.510
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.490 0.510
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.490 0.510
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.490 0.510
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.490 0.510
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.490 0.510
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.490 0.510
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.490 0.510
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.490 0.510
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.490 0.510
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.490 0.510
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.490 0.510
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.490 0.510
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.490 0.510
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.490 0.510
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.490 0.510
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.490 0.510
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.490 0.510
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.490 0.510
L40.8 Other psoriasis
0.000 0.491 0.509
E11.4 With neurological complications
0.000 0.491 0.509
E11.2 With renal complications
0.000 0.492 0.508
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.492 0.508
M12.2 Villonodular synovitis (pigmented)
0.000 0.493 0.507
J40 Bronchitis, not specified as acute or chronic
0.000 0.494 0.506
M10.4 Other secondary gout
0.000 0.494 0.506
M10.3 Gout due to impairment of renal function
0.000 0.494 0.506
M10.2 Drug-induced gout
0.000 0.494 0.506
M10.1 Lead-induced gout
0.000 0.494 0.506
E26 Hyperaldosteronism
0.000 0.496 0.504
E78.8 Other disorders of lipoprotein metabolism
0.000 0.497 0.503
E84 Cystic fibrosis
0.000 0.497 0.502
Chapter VI Diseases of the nervous system
0.000 0.499 0.501
E50.9 Vitamin A deficiency, unspecified
0.000 0.501 0.499
E50.8 Other manifestations of vitamin A deficiency
0.000 0.501 0.499
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.501 0.499
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.501 0.499
E50.5 Vitamin A deficiency with night blindness
0.000 0.501 0.499
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.501 0.499
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.501 0.499
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.501 0.499
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.501 0.499
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.501 0.499
E56.9 Vitamin deficiency, unspecified
0.000 0.501 0.499
E56.8 Deficiency of other vitamins
0.000 0.501 0.499
E56.1 Deficiency of vitamin K
0.000 0.501 0.499
E56.0 Deficiency of vitamin E
0.000 0.501 0.499
E63.9 Nutritional deficiency, unspecified
0.000 0.501 0.499
E63.8 Other specified nutritional deficiencies
0.000 0.501 0.499
E63.1 Imbalance of constituents of food intake
0.000 0.501 0.499
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.501 0.499
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.501 0.499
E64.8 Sequelae of other nutritional deficiencies
0.000 0.501 0.499
E64.3 Sequelae of rickets
0.000 0.501 0.499
E64.2 Sequelae of vitamin C deficiency
0.000 0.501 0.499
E64.1 Sequelae of vitamin A deficiency
0.000 0.501 0.499
E64.0 Sequelae of protein-energy malnutrition
0.000 0.501 0.499
E04.1 Non-toxic single thyroid nodule
0.000 0.501 0.499
K90 Intestinal malabsorption
0.000 0.501 0.499
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.503 0.497
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.503 0.497
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.503 0.497
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.503 0.497
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.503 0.497
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.503 0.497
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.503 0.497
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.503 0.497
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.503 0.497
J00-J06 Acute upper respiratory infections
0.000 0.504 0.496
# Top node
0.000 0.504 0.496
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.505 0.495
E24.8 Other Cushing's syndrome
0.000 0.505 0.495
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.505 0.495
E24.3 Ectopic ACTH syndrome
0.000 0.505 0.495
E24.1 Nelson's syndrome
0.000 0.505 0.495
E07.1 Dyshormogenetic goitre
0.000 0.507 0.492
E07.0 Hypersecretion of calcitonin
0.000 0.507 0.492
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.508 0.492
E23 Hypofunction and other disorders of pituitary gland
0.000 0.510 0.490
E28 Ovarian dysfunction
0.000 0.510 0.490
E51.9 Thiamine deficiency, unspecified
0.000 0.510 0.490
E51.8 Other manifestations of thiamine deficiency
0.000 0.510 0.490
E51.1 Beriberi
0.000 0.510 0.490
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.511 0.489
E25.9 Adrenogenital disorder, unspecified
0.000 0.514 0.486
E25.8 Other adrenogenital disorders
0.000 0.514 0.486
E34.8 Other specified endocrine disorders
0.000 0.515 0.485
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.515 0.485
J81 Pulmonary oedema
0.000 0.515 0.485
E30.9 Disorder of puberty, unspecified
0.000 0.516 0.484
E30.8 Other disorders of puberty
0.000 0.516 0.484
E30.1 Precocious puberty
0.000 0.516 0.484
E30.0 Delayed puberty
0.000 0.516 0.484
E31.9 Polyglandular dysfunction, unspecified
0.000 0.516 0.484
E31.8 Other polyglandular dysfunction
0.000 0.516 0.484
E31.1 Polyglandular hyperfunction
0.000 0.516 0.484
E31.0 Autoimmune polyglandular failure
0.000 0.516 0.484
E32.9 Disease of thymus, unspecified
0.000 0.516 0.484
E32.8 Other diseases of thymus
0.000 0.516 0.484
E32.1 Abscess of thymus
0.000 0.516 0.484
E32.0 Persistent hyperplasia of thymus
0.000 0.516 0.484
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.516 0.484
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.516 0.484
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.516 0.484
G36.0 Neuromyelitis optica [Devic]
0.000 0.517 0.483

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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