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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3135322
log Bayes Factor = 53.1371
Chromosome 6   position 28,946,920  (GRCh37) Explore rs3135322 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.004 0.996
E16.2 Hypoglycaemia, unspecified
0.000 0.005 0.995
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.006 0.994
E00-E07 Disorders of thyroid gland
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.048 0.952
E10.2 With renal complications
0.000 0.056 0.944
E10.4 With neurological complications
0.000 0.101 0.899
E10.1 With ketoacidosis
0.000 0.113 0.887
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.827 0.173 0.000
E05.8 Other thyrotoxicosis
0.000 0.187 0.813
E13 Other specified diabetes mellitus
0.000 0.215 0.785
E16.1 Other hypoglycaemia
0.000 0.247 0.753
E10.7 With multiple complications
0.000 0.251 0.749
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.261 0.738
E10.0 With coma
0.000 0.279 0.721
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.287 0.713
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.287 0.713
E16.4 Abnormal secretion of gastrin
0.000 0.287 0.713
E16.3 Increased secretion of glucagon
0.000 0.287 0.713
E15 Nondiabetic hypoglycaemic coma
0.000 0.287 0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.712
E14 Unspecified diabetes mellitus
0.000 0.299 0.701
E40-E46 Malnutrition
0.000 0.313 0.687
E10.6 With other specified complications
0.000 0.332 0.668
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.333 0.667
E10.5 With peripheral circulatory complications
0.000 0.354 0.646
E13.9 Without complications
0.000 0.369 0.631
E07 Other disorders of thyroid
0.000 0.386 0.614
E14.3 With ophthalmic complications
0.000 0.407 0.593
E06 Thyroiditis
0.000 0.416 0.583
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.427 0.573
E13.3 With ophthalmic complications
0.000 0.433 0.567
E14.1 With ketoacidosis
0.000 0.435 0.565
E13.8 With unspecified complications
0.000 0.437 0.563
E13.7 With multiple complications
0.000 0.437 0.563
E13.6 With other specified complications
0.000 0.437 0.563
E13.5 With peripheral circulatory complications
0.000 0.437 0.563
E13.4 With neurological complications
0.000 0.437 0.563
E13.2 With renal complications
0.000 0.437 0.563
E13.1 With ketoacidosis
0.000 0.437 0.563
E13.0 With coma
0.000 0.437 0.563
E14.6 With other specified complications
0.000 0.467 0.533
E14.8 With unspecified complications
0.000 0.472 0.528
E14.4 With neurological complications
0.000 0.479 0.521
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.510
E10.8 With unspecified complications
0.000 0.492 0.507
E14.7 With multiple complications
0.000 0.497 0.503
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.507 0.493
E45 Retarded development following protein-energy malnutrition
0.000 0.507 0.493
E43 Unspecified severe protein-energy malnutrition
0.000 0.507 0.493
E42 Marasmic kwashiorkor
0.000 0.507 0.493
E41 Nutritional marasmus
0.000 0.507 0.493
E40 Kwashiorkor
0.000 0.507 0.493
E07.8 Other specified disorders of thyroid
0.000 0.515 0.485
E14.2 Withrenal complications
0.000 0.520 0.479
E14.5 With peripheral circulatory complications
0.000 0.526 0.474
E06.9 Thyroiditis, unspecified
0.000 0.529 0.471
E14.0 With coma
0.000 0.529 0.470
E03 Other hypothyroidism
0.000 0.530 0.470
E46 Unspecified protein-energy malnutrition
0.000 0.533 0.467
E07.1 Dyshormogenetic goitre
0.000 0.560 0.440
E07.0 Hypersecretion of calcitonin
0.000 0.560 0.440
E06.1 Subacute thyroiditis
0.000 0.561 0.438
E06.4 Drug-induced thyroiditis
0.000 0.581 0.418
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.581 0.418
E06.0 Acute thyroiditis
0.000 0.581 0.418
K90 Intestinal malabsorption
0.000 0.596 0.403
E06.5 Other chronic thyroiditis
0.000 0.599 0.401
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.616 0.384
E44.1 Mild protein-energy malnutrition
0.000 0.646 0.353
E44.0 Moderate protein-energy malnutrition
0.000 0.646 0.353
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.648 0.352
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.657 0.343
E03.5 Myxoedema coma
0.000 0.663 0.337
E03.4 Atrophy of thyroid (acquired)
0.000 0.663 0.337
E03.3 Postinfectious hypothyroidism
0.000 0.663 0.337
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.663 0.337
E50-E64 Other nutritional deficiencies
0.000 0.666 0.334
E03.1 Congenital hypothyroidism without goitre
0.000 0.675 0.324
E11 Non-insulin-dependent diabetes mellitus
0.000 0.679 0.321
E65-E68 Obesity and other hyperalimentation
0.000 0.679 0.321
E11.6 With other specified complications
0.000 0.708 0.292
K90.3 Pancreatic steatorrhoea
0.000 0.710 0.289
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.710 0.289
K90.1 Tropical sprue
0.000 0.710 0.289
E03.8 Other specified hypothyroidism
0.000 0.714 0.286
E11.1 With ketoacidosis
0.000 0.719 0.281
K90.8 Other intestinal malabsorption
0.000 0.724 0.276
E11.0 With coma
0.000 0.734 0.266
E07.9 Disorder of thyroid, unspecified
0.000 0.753 0.247
E54 Ascorbic acid deficiency
0.000 0.757 0.243
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.760 0.240
E63 Other nutritional deficiencies
0.000 0.760 0.240
E50 Vitamin A deficiency
0.000 0.760 0.240
E60 Dietary zinc deficiency
0.000 0.760 0.240
E59 Dietary selenium deficiency
0.000 0.760 0.240
E52 Niacin deficiency [pellagra]
0.000 0.760 0.240
E11.2 With renal complications
0.000 0.761 0.239
E51 Thiamine deficiency
0.000 0.762 0.238
E11.7 With multiple complications
0.000 0.770 0.230
E67 Other hyperalimentation
0.000 0.770 0.230
E68 Sequelae of hyperalimentation
0.000 0.770 0.230
E56 Other vitamin deficiencies
0.000 0.774 0.226
E58 Dietary calcium deficiency
0.000 0.782 0.218
E55 Vitamin D deficiency
0.000 0.793 0.207
M45.X9 Ankylosing spondylitis (Site unspecified)
0.200 0.800 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.806 0.194
E61 Deficiency of other nutrient elements
0.000 0.806 0.193
I83 Varicose veins of lower extremities
0.189 0.811 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.813 0.186
E20-E35 Disorders of other endocrine glands
0.000 0.815 0.184
E11.8 With unspecified complications
0.000 0.820 0.180
E50.9 Vitamin A deficiency, unspecified
0.000 0.828 0.172
E50.8 Other manifestations of vitamin A deficiency
0.000 0.828 0.172
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.828 0.172
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.828 0.172
E50.5 Vitamin A deficiency with night blindness
0.000 0.828 0.172
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.828 0.172
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.828 0.172
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.828 0.172
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.828 0.172
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.828 0.172
E63.9 Nutritional deficiency, unspecified
0.000 0.828 0.172
E63.8 Other specified nutritional deficiencies
0.000 0.828 0.172
E63.1 Imbalance of constituents of food intake
0.000 0.828 0.172
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.828 0.172
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.828 0.172
E64.8 Sequelae of other nutritional deficiencies
0.000 0.828 0.172
E64.3 Sequelae of rickets
0.000 0.828 0.172
E64.2 Sequelae of vitamin C deficiency
0.000 0.828 0.172
E64.1 Sequelae of vitamin A deficiency
0.000 0.828 0.172
E64.0 Sequelae of protein-energy malnutrition
0.000 0.828 0.172
E65 Localised adiposity
0.000 0.828 0.172
E51.9 Thiamine deficiency, unspecified
0.000 0.829 0.171
E51.8 Other manifestations of thiamine deficiency
0.000 0.829 0.171
E51.1 Beriberi
0.000 0.829 0.171
E51.2 Wernicke's encephalopathy
0.000 0.831 0.169
E24 Cushing's syndrome
0.000 0.831 0.169
E67.8 Other specified hyperalimentation
0.000 0.835 0.165
E67.3 Hypervitaminosis D
0.000 0.835 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.835 0.165
E67.1 Hypercarotenaemia
0.000 0.835 0.165
E67.0 Hypervitaminosis A
0.000 0.835 0.165
E83 Disorders of mineral metabolism
0.145 0.836 0.019
E56.9 Vitamin deficiency, unspecified
0.000 0.838 0.162
E56.8 Deficiency of other vitamins
0.000 0.838 0.162
E56.0 Deficiency of vitamin E
0.000 0.838 0.162
E53 Deficiency of other B group vitamins
0.000 0.838 0.162
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.840 0.160
E21.3 Hyperparathyroidism, unspecified
0.000 0.847 0.153
E56.1 Deficiency of vitamin K
0.000 0.851 0.148
E55.0 Rickets, active
0.000 0.851 0.148
E24.9 Cushing's syndrome, unspecified
0.000 0.856 0.144
E24.0 Pituitary-dependent Cushing's disease
0.000 0.860 0.140
E06.3 Autoimmune thyroiditis
0.001 0.861 0.138
E61.9 Deficiency of nutrient element, unspecified
0.000 0.861 0.139
E61.8 Deficiency of other specified nutrient elements
0.000 0.861 0.139
E61.7 Deficiency of multiple nutrient elements
0.000 0.861 0.139
E61.6 Vanadium deficiency
0.000 0.861 0.139
E61.5 Molybdenum deficiency
0.000 0.861 0.139
E61.4 Chromium deficiency
0.000 0.861 0.139
E61.3 Manganese deficiency
0.000 0.861 0.139
E61.0 Copper deficiency
0.000 0.861 0.139
E20 Hypoparathyroidism
0.000 0.862 0.138
E11.5 With peripheral circulatory complications
0.000 0.865 0.135
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.867 0.132
E32 Diseases of thymus
0.000 0.867 0.132
E30 Disorders of puberty, not elsewhere classified
0.000 0.867 0.132
E24.2 Drug-induced Cushing's syndrome
0.000 0.868 0.132
I83.0 Varicose veins of lower extremities with ulcer
0.129 0.871 0.000
E14.9 Without complications
0.000 0.871 0.129
E25 Adrenogenital disorders
0.000 0.872 0.128
E83.3 Disorders of phosphorus metabolism
0.122 0.873 0.005
E31 Polyglandular dysfunction
0.000 0.874 0.126
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.123 0.877 0.000
E28 Ovarian dysfunction
0.000 0.878 0.122
E61.2 Magnesium deficiency
0.000 0.878 0.122
E24.8 Other Cushing's syndrome
0.000 0.879 0.121
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.879 0.121
E24.3 Ectopic ACTH syndrome
0.000 0.879 0.121
E24.1 Nelson's syndrome
0.000 0.879 0.121
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.879 0.121
E53.9 Vitamin B deficiency, unspecified
0.000 0.881 0.119
E83.8 Other disorders of mineral metabolism
0.104 0.882 0.014
E83.2 Disorders of zinc metabolism
0.104 0.882 0.014
E83.0 Disorders of copper metabolism
0.104 0.882 0.014
E83.9 Disorder of mineral metabolism, unspecified
0.104 0.883 0.014
E53.1 Pyridoxine deficiency
0.000 0.884 0.116
E53.0 Riboflavin deficiency
0.000 0.884 0.116
E61.1 Iron deficiency
0.000 0.884 0.116
E55.9 Vitamin D deficiency, unspecified
0.000 0.884 0.116
E21.2 Other hyperparathyroidism
0.000 0.885 0.115
E21.4 Other specified disorders of parathyroid gland
0.000 0.885 0.115
E29 Testicular dysfunction
0.000 0.886 0.114
E11.3 With ophthalmic complications
0.000 0.887 0.113
E20.9 Hypoparathyroidism, unspecified
0.000 0.895 0.105
E34 Other endocrine disorders
0.000 0.897 0.103
M45 Ankylosing spondylitis
0.102 0.898 0.000
E20.8 Other hypoparathyroidism
0.000 0.901 0.099
E20.1 Pseudohypoparathyroidism
0.000 0.901 0.099
E20.0 Idiopathic hypoparathyroidism
0.000 0.901 0.099
E30.9 Disorder of puberty, unspecified
0.000 0.905 0.095
E30.8 Other disorders of puberty
0.000 0.905 0.095
E30.1 Precocious puberty
0.000 0.905 0.095
E30.0 Delayed puberty
0.000 0.905 0.095
E32.9 Disease of thymus, unspecified
0.000 0.905 0.095
E32.8 Other diseases of thymus
0.000 0.905 0.095
E32.1 Abscess of thymus
0.000 0.905 0.095
E32.0 Persistent hyperplasia of thymus
0.000 0.905 0.095
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.905 0.095
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.905 0.095
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.905 0.095
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.906 0.093
E25.9 Adrenogenital disorder, unspecified
0.000 0.908 0.092
E25.8 Other adrenogenital disorders
0.000 0.908 0.092
E31.9 Polyglandular dysfunction, unspecified
0.000 0.909 0.091
E31.8 Other polyglandular dysfunction
0.000 0.909 0.091
E31.1 Polyglandular hyperfunction
0.000 0.909 0.091
E28.2 Polycystic ovarian syndrome
0.000 0.910 0.089
E28.9 Ovarian dysfunction, unspecified
0.000 0.912 0.088
E28.8 Other ovarian dysfunction
0.000 0.912 0.088
E28.1 Androgen excess
0.000 0.912 0.088
E28.0 Oestrogen excess
0.000 0.912 0.088
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.912 0.088
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.912 0.087
E26 Hyperaldosteronism
0.000 0.913 0.086
E31.0 Autoimmune polyglandular failure
0.000 0.915 0.084
E29.9 Testicular dysfunction, unspecified
0.000 0.917 0.083
E70-E90 Metabolic disorders
0.001 0.917 0.081
E21.0 Primary hyperparathyroidism
0.000 0.918 0.082
E29.8 Other testicular dysfunction
0.000 0.918 0.082
E29.0 Testicular hyperfunction
0.000 0.918 0.082
M45.X2 Ankylosing spondylitis (Cervical region)
0.081 0.919 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.921 0.079
M45.X6 Ankylosing spondylitis (Lumbar region)
0.078 0.921 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.923 0.077
E28.3 Primary ovarian failure
0.000 0.924 0.076
E22 Hyperfunction of pituitary gland
0.000 0.925 0.075
E34.3 Short stature, not elsewhere classified
0.000 0.925 0.075
E34.5 Androgen resistance syndrome
0.000 0.926 0.074
E34.4 Constitutional tall stature
0.000 0.926 0.074
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.926 0.074
E34.1 Other hypersecretion of intestinal hormones
0.000 0.926 0.074
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.073 0.927 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.073 0.927 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.073 0.927 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.073 0.927 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.073 0.927 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.073 0.927 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.930 0.070
I83.1 Varicose veins of lower extremities with inflammation
0.070 0.930 0.000
E11.4 With neurological complications
0.000 0.931 0.069
E78.1 Pure hyperglyceridaemia
0.000 0.931 0.069
E34.8 Other specified endocrine disorders
0.000 0.931 0.069
E23 Hypofunction and other disorders of pituitary gland
0.000 0.931 0.069
E34.9 Endocrine disorder, unspecified
0.000 0.933 0.067
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.935 0.064
E74 Other disorders of carbohydrate metabolism
0.001 0.937 0.062
E26.8 Other hyperaldosteronism
0.000 0.938 0.062
E26.1 Secondary hyperaldosteronism
0.000 0.938 0.062
E78.6 Lipoprotein deficiency
0.000 0.938 0.061
E34.0 Carcinoid syndrome
0.000 0.939 0.061
E29.1 Testicular hypofunction
0.000 0.939 0.061
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.060 0.940 0.000
E78.3 Hyperchylomicronaemia
0.000 0.940 0.060
E23.7 Disorder of pituitary gland, unspecified
0.000 0.940 0.060
E77 Disorders of glycoprotein metabolism
0.001 0.940 0.058
E76 Disorders of glycosaminoglycan metabolism
0.001 0.940 0.058
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.940 0.058
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.940 0.058
R31 Unspecified haematuria
0.059 0.941 0.000
E88 Other metabolic disorders
0.000 0.941 0.058
E73 Lactose intolerance
0.001 0.941 0.058
E84 Cystic fibrosis
0.001 0.942 0.057
E85 Amyloidosis
0.001 0.942 0.057
E70 Disorders of aromatic amino-acid metabolism
0.001 0.943 0.055
E79 Disorders of purine and pyrimidine metabolism
0.001 0.944 0.054
E26.9 Hyperaldosteronism, unspecified
0.001 0.945 0.054
E22.8 Other hyperfunction of pituitary gland
0.000 0.946 0.054
E72 Other disorders of amino-acid metabolism
0.001 0.946 0.053
E83.4 Disorders of magnesium metabolism
0.044 0.946 0.009
E22.1 Hyperprolactinaemia
0.000 0.947 0.053
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.947 0.053
E75.5 Other lipid storage disorders
0.001 0.949 0.051
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.949 0.051
E78.4 Other hyperlipidaemia
0.000 0.950 0.050
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.950 0.050
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.950 0.050
E23.1 Drug-induced hypopituitarism
0.000 0.950 0.050
E88.9 Metabolic disorder, unspecified
0.000 0.952 0.048
E85.4 Organ-limited amyloidosis
0.000 0.953 0.047
E75.2 Other sphingolipidosis
0.001 0.953 0.047
E75.6 Lipid storage disorder, unspecified
0.001 0.953 0.046
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.953 0.046
E75.3 Sphingolipidosis, unspecified
0.001 0.953 0.046
E75.1 Other gangliosidosis
0.001 0.953 0.046
E75.0 GM2 gangliosidosis
0.001 0.953 0.046
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.954 0.045
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.954 0.045
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.954 0.045
E74.2 Disorders of galactose metabolism
0.001 0.954 0.045
E74.1 Disorders of fructose metabolism
0.001 0.954 0.045
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.955 0.045
E88.2 Lipomatosis, not elsewhere classified
0.000 0.955 0.044
E74.0 Glycogen storage disease
0.001 0.956 0.044
E04 Other non-toxic goitre
0.002 0.956 0.042
E85.8 Other amyloidosis
0.001 0.957 0.043
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.957 0.042
E71.3 Disorders of fatty-acid metabolism
0.001 0.957 0.042
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.957 0.042
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.957 0.042
E71.0 Maple-syrup-urine disease
0.001 0.957 0.042
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.957 0.042
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.957 0.042
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.957 0.042
E76.2 Other mucopolysaccharidoses
0.001 0.957 0.042
E76.1 Mucopolysaccharidosis, type II
0.001 0.957 0.042
E76.0 Mucopolysaccharidosis, type I
0.001 0.957 0.042
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.957 0.042
E77.8 Other disorders of glycoprotein metabolism
0.001 0.957 0.042
E77.1 Defects in glycoprotein degradation
0.001 0.957 0.042
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.957 0.042
E73.8 Other lactose intolerance
0.001 0.958 0.042
E73.1 Secondary lactase deficiency
0.001 0.958 0.042
E73.0 Congenital lactase deficiency
0.001 0.958 0.042
E84.8 Cystic fibrosis with other manifestations
0.001 0.958 0.041
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.958 0.041
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.958 0.042
E73.9 Lactose intolerance, unspecified
0.001 0.958 0.041
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.958 0.041
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.958 0.041
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.958 0.041
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.959 0.040
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.959 0.040
E70.2 Disorders of tyrosine metabolism
0.001 0.959 0.040
E70.1 Other hyperphenylalaninaemias
0.001 0.959 0.040
E70.0 Classical phenylketonuria
0.001 0.959 0.040
E85.3 Secondary systemic amyloidosis
0.001 0.960 0.040
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.960 0.039
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.960 0.039
E79.1 Lesch-Nyhan syndrome
0.001 0.960 0.039
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.040 0.960 0.000
E84.9 Cystic fibrosis, unspecified
0.001 0.960 0.039
E88.8 Other specified metabolic disorders
0.000 0.960 0.039
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.961 0.038
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.961 0.038
E72.5 Disorders of glycine metabolism
0.001 0.961 0.038
E72.4 Disorders of ornithine metabolism
0.001 0.961 0.038
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.961 0.038
E72.2 Disorders of urea cycle metabolism
0.001 0.961 0.038
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.038 0.962 0.000
E72.0 Disorders of amino-acid transport
0.001 0.962 0.037
E70.3 Albinism
0.001 0.962 0.037
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.963 0.037
C15 Malignant neoplasm of oesophagus
0.000 0.964 0.036
I73.9 Peripheral vascular disease, unspecified
0.000 0.964 0.036
I89.0 Lymphoedema, not elsewhere classified
0.036 0.964 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.964 0.035
E78.8 Other disorders of lipoprotein metabolism
0.000 0.964 0.036
I73 Other peripheral vascular diseases
0.000 0.964 0.036
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.965 0.034
I77 Other disorders of arteries and arterioles
0.000 0.965 0.035
E88.3 Tumour lysis syndrome
0.001 0.965 0.034
C15-C26 Malignant neoplasms of digestive organs
0.000 0.965 0.035
Z71.8 Other specified counselling
0.035 0.965 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.965 0.034
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.034 0.965 0.000
C20 Malignant neoplasm of rectum
0.000 0.966 0.034
I86 Varicose veins of other sites
0.034 0.966 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.966 0.034
E23.6 Other disorders of pituitary gland
0.000 0.967 0.033
E26.0 Primary hyperaldosteronism
0.001 0.967 0.032
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.967 0.033
C15.4 Middle third of oesophagus
0.000 0.967 0.033
I77.6 Arteritis, unspecified
0.000 0.967 0.033
C15.5 Lower third of oesophagus
0.000 0.968 0.032
E23.2 Diabetes insipidus
0.000 0.968 0.032
I74 Arterial embolism and thrombosis
0.000 0.968 0.032
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.968 0.031
E04.8 Other specified non-toxic goitre
0.001 0.968 0.030
I86.8 Varicose veins of other specified sites
0.031 0.969 0.000
I73.0 Raynaud's syndrome
0.000 0.969 0.031
E53.8 Deficiency of other specified B group vitamins
0.000 0.969 0.031
I81 Portal vein thrombosis
0.030 0.970 0.000
C15.9 Oesophagus, unspecified
0.000 0.970 0.030
I74.5 Embolism and thrombosis of iliac artery
0.000 0.970 0.030
I77.8 Other specified disorders of arteries and arterioles
0.000 0.970 0.030
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.970 0.030
I89.1 Lymphangitis
0.030 0.970 0.000
I72 Other aneurysm
0.000 0.971 0.029
I86.4 Gastric varices
0.028 0.972 0.000
C25 Malignant neoplasm of pancreas
0.000 0.972 0.028
I85 Oesophageal varices
0.028 0.972 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.972 0.028
C15.0 Cervical part of oesophagus
0.000 0.972 0.028
E85.9 Amyloidosis, unspecified
0.001 0.972 0.027
I82 Other venous embolism and thrombosis
0.028 0.972 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.972 0.027
C15.3 Upper third of oesophagus
0.000 0.973 0.027
I77.3 Arterial fibromuscular dysplasia
0.000 0.973 0.027
I77.1 Stricture of artery
0.000 0.973 0.027
C15.1 Thoracic part of oesophagus
0.000 0.973 0.026
C15.8 Overlapping lesion of oesophagus
0.000 0.974 0.026
C15.2 Abdominal part of oesophagus
0.000 0.974 0.026
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.974 0.026
I72.4 Aneurysm of artery of lower extremity
0.000 0.974 0.026
E66 Obesity
0.000 0.974 0.026
I86.3 Vulval varices
0.026 0.974 0.000
C17 Malignant neoplasm of small intestine
0.000 0.974 0.026
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.974 0.026
I77.2 Rupture of artery
0.000 0.974 0.025
I86.2 Pelvic varices
0.025 0.974 0.000
I77.5 Necrosis of artery
0.000 0.975 0.025
I77.4 Coeliac artery compression syndrome
0.000 0.975 0.025
K90-K93 Other diseases of the digestive system
0.000 0.975 0.025
C17.0 Duodenum
0.000 0.975 0.025
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.975 0.025
I86.0 Sublingual varices
0.025 0.975 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.975 0.025
I70 Atherosclerosis
0.000 0.975 0.025
I72.3 Aneurysm of iliac artery
0.000 0.976 0.024
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.976 0.024
I72.1 Aneurysm of artery of upper extremity
0.000 0.976 0.024
C25.3 Pancreatic duct
0.000 0.976 0.024
E80.2 Other porphyria
0.001 0.976 0.023
I85.9 Oesophageal varices without bleeding
0.024 0.976 0.000
I88 Nonspecific lymphadenitis
0.023 0.976 0.000
I87 Other disorders of veins
0.023 0.977 0.000
C25.2 Tail of pancreas
0.000 0.977 0.023
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.977 0.023
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.977 0.022
E80.5 Crigler-Najjar syndrome
0.001 0.977 0.022
E80.3 Defects of catalase and peroxydase
0.001 0.977 0.022
E80.0 Hereditary erythropoietic porphyria
0.001 0.977 0.022
C25.1 Body of pancreas
0.000 0.977 0.023
I82.8 Embolism and thrombosis of other specified veins
0.023 0.977 0.000
E04.0 Non-toxic diffuse goitre
0.002 0.978 0.021
I72.0 Aneurysm of carotid artery
0.000 0.978 0.022
C25.8 Overlapping lesion of pancreas
0.000 0.978 0.022
C24.0 Extrahepatic bile duct
0.000 0.978 0.022
C25.4 Endocrine pancreas
0.000 0.978 0.022
I82.0 Budd-Chiari syndrome
0.022 0.978 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.979 0.021
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.979 0.021
C21 Malignant neoplasm of anus and anal canal
0.000 0.979 0.021
E23.0 Hypopituitarism
0.000 0.979 0.021
E27 Other disorders of adrenal gland
0.000 0.979 0.020
E11.9 Without complications
0.000 0.979 0.021
E80.1 Porphyria cutanea tarda
0.001 0.980 0.019
I82.1 Thrombophlebitis migrans
0.020 0.980 0.000
E80.6 Other disorders of bilirubin metabolism
0.001 0.980 0.019
M45-M49 Spondylopathies
0.020 0.980 0.000
I72.2 Aneurysm of renal artery
0.000 0.981 0.019
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.981 0.019
E83.5 Disorders of calcium metabolism
0.005 0.981 0.014
I72.9 Aneurysm of unspecified site
0.000 0.981 0.019
I82.3 Embolism and thrombosis of renal vein
0.019 0.981 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.981 0.019
I70.8 Atherosclerosis of other arteries
0.000 0.981 0.019
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.981 0.019
E66.1 Drug-induced obesity
0.000 0.981 0.019
C17.8 Overlapping lesion of small intestine
0.000 0.981 0.018
C17.3 Meckel's diverticulum
0.000 0.981 0.018
C25.7 Other parts of pancreas
0.000 0.981 0.018
I70.1 Atherosclerosis of renal artery
0.000 0.981 0.018
I79.1 Aortitis in diseases classified elsewhere
0.000 0.981 0.018
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.981 0.018
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.982 0.018
C25.9 Pancreas, unspecified
0.000 0.982 0.018

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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