TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs3135333
log Bayes Factor = 19.888
Chromosome 6   position 32,963,784  (GRCh37) Explore rs3135333 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.996 0.004 0.000
E03 Other hypothyroidism
0.531 0.468 0.001
E10 Insulin-dependent diabetes mellitus
0.000 0.559 0.441
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.435 0.565 0.001
E10.9 Without complications
0.000 0.567 0.433
E10.4 With neurological complications
0.000 0.575 0.425
E10.1 With ketoacidosis
0.000 0.575 0.425
E10.2 With renal complications
0.000 0.577 0.423
E03.1 Congenital hypothyroidism without goitre
0.410 0.589 0.001
E10.3 With ophthalmic complications
0.000 0.606 0.394
E03.5 Myxoedema coma
0.381 0.619 0.001
E03.4 Atrophy of thyroid (acquired)
0.381 0.619 0.001
E03.3 Postinfectious hypothyroidism
0.381 0.619 0.001
E03.0 Congenital hypothyroidism with diffuse goitre
0.381 0.619 0.001
E10.8 With unspecified complications
0.000 0.672 0.328
E10.7 With multiple complications
0.000 0.683 0.317
E10.5 With peripheral circulatory complications
0.000 0.740 0.260
E03.8 Other specified hypothyroidism
0.257 0.742 0.001
K90 Intestinal malabsorption
0.000 0.746 0.254
E10.0 With coma
0.000 0.759 0.241
E10.6 With other specified complications
0.000 0.770 0.230
E10-E14 Diabetes mellitus
0.001 0.798 0.201
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.798 0.202
K90.3 Pancreatic steatorrhoea
0.000 0.817 0.182
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.817 0.182
K90.1 Tropical sprue
0.000 0.817 0.182
E00-E07 Disorders of thyroid gland
0.174 0.823 0.003
E11 Non-insulin-dependent diabetes mellitus
0.000 0.832 0.168
E13 Other specified diabetes mellitus
0.001 0.837 0.162
E11.4 With neurological complications
0.000 0.844 0.156
E11.5 With peripheral circulatory complications
0.000 0.846 0.154
E07 Other disorders of thyroid
0.152 0.847 0.001
E12 Malnutrition-related diabetes mellitus
0.001 0.855 0.145
E13.9 Without complications
0.000 0.858 0.142
E02 Subclinical iodine-deficiency hypothyroidism
0.130 0.868 0.002
E07.8 Other specified disorders of thyroid
0.131 0.869 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.871 0.129
E11.8 With unspecified complications
0.000 0.872 0.128
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.125 0.873 0.003
E00 Congenital iodine-deficiency syndrome
0.125 0.873 0.003
K90.8 Other intestinal malabsorption
0.000 0.873 0.126
E11.3 With ophthalmic complications
0.000 0.875 0.125
E11.7 With multiple complications
0.000 0.879 0.121
E07.9 Disorder of thyroid, unspecified
0.120 0.880 0.000
E06 Thyroiditis
0.117 0.882 0.001
E13.8 With unspecified complications
0.001 0.883 0.117
E13.7 With multiple complications
0.001 0.883 0.117
E13.6 With other specified complications
0.001 0.883 0.117
E13.5 With peripheral circulatory complications
0.001 0.883 0.117
E13.4 With neurological complications
0.001 0.883 0.117
E13.2 With renal complications
0.001 0.883 0.117
E13.1 With ketoacidosis
0.001 0.883 0.117
E13.0 With coma
0.001 0.883 0.117
E11.1 With ketoacidosis
0.000 0.884 0.116
E04 Other non-toxic goitre
0.115 0.884 0.000
E11.2 With renal complications
0.000 0.884 0.116
E07.1 Dyshormogenetic goitre
0.109 0.890 0.001
E07.0 Hypersecretion of calcitonin
0.109 0.890 0.001
E04.2 Non-toxic multinodular goitre
0.109 0.891 0.000
E11.0 With coma
0.000 0.895 0.104
E12.9 Without complications
0.001 0.896 0.104
E12.8 With unspecified complications
0.001 0.896 0.104
E12.7 With multiple complications
0.001 0.896 0.104
E12.6 With other specified complications
0.001 0.896 0.104
E12.5 With peripheral circulatory complications
0.001 0.896 0.104
E12.4 With neurological complications
0.001 0.896 0.104
E12.3 With ophthalmic complications
0.001 0.896 0.104
E12.2 With renal complications
0.001 0.896 0.104
E12.1 With ketoacidosis
0.001 0.896 0.104
E12.0 With coma
0.001 0.896 0.104
E13.3 With ophthalmic complications
0.001 0.900 0.099
E11.6 With other specified complications
0.000 0.901 0.098
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.089 0.909 0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.089 0.909 0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.089 0.909 0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.089 0.909 0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.089 0.909 0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.089 0.909 0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.089 0.909 0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.089 0.909 0.002
E06.1 Subacute thyroiditis
0.087 0.912 0.001
E06.9 Thyroiditis, unspecified
0.084 0.915 0.001
E06.4 Drug-induced thyroiditis
0.084 0.915 0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.084 0.915 0.001
E06.0 Acute thyroiditis
0.084 0.915 0.001
E06.5 Other chronic thyroiditis
0.084 0.915 0.001
E04.8 Other specified non-toxic goitre
0.083 0.917 0.000
E06.3 Autoimmune thyroiditis
0.072 0.927 0.001
E04.0 Non-toxic diffuse goitre
0.069 0.931 0.001
E14 Unspecified diabetes mellitus
0.000 0.931 0.068
E04.1 Non-toxic single thyroid nodule
0.068 0.932 0.000
E14.8 With unspecified complications
0.000 0.943 0.056
C78.7 Secondary malignant neoplasm of liver
0.054 0.946 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.052 0.948 0.000
E14.6 With other specified complications
0.000 0.948 0.052
E14.2 Withrenal complications
0.000 0.949 0.051
C78.0 Secondary malignant neoplasm of lung
0.050 0.950 0.000
E14.7 With multiple complications
0.000 0.950 0.049
C78.2 Secondary malignant neoplasm of pleura
0.047 0.953 0.000
E14.3 With ophthalmic complications
0.000 0.955 0.045
E14.4 With neurological complications
0.000 0.955 0.045
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.043 0.957 0.000
C77.9 Lymph node, unspecified
0.042 0.958 0.000
E14.1 With ketoacidosis
0.000 0.958 0.042
E14.0 With coma
0.000 0.959 0.041
E14.5 With peripheral circulatory complications
0.000 0.959 0.040
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.040 0.960 0.000
G35 Multiple sclerosis
0.038 0.962 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.038 0.962 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.038 0.962 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.038 0.962 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.037 0.963 0.000
C77.8 Lymph nodes of multiple regions
0.036 0.964 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.032 0.968 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.016 0.968 0.015
C77.5 Intrapelvic lymph nodes
0.029 0.971 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.025 0.971 0.004
C76 Malignant neoplasm of other and ill-defined sites
0.029 0.971 0.000
C80 Malignant neoplasm without specification of site
0.028 0.972 0.000
C77.4 Inguinal and lower limb lymph nodes
0.027 0.973 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.026 0.974 0.000
E04.9 Non-toxic goitre, unspecified
0.026 0.974 0.000
E14.9 Without complications
0.000 0.976 0.024
C76.3 Pelvis
0.023 0.977 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.008 0.977 0.014
C80.0 Malignant neoplasm, primary site unknown, so stated
0.022 0.978 0.000
E40-E46 Malnutrition
0.008 0.978 0.014
G35-G37 Demyelinating diseases of the central nervous system
0.021 0.978 0.000
E05.5 Thyroid crisis or storm
0.018 0.979 0.003
E05.4 Thyrotoxicosis factitia
0.018 0.979 0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.018 0.979 0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.018 0.979 0.003
C76.8 Overlapping lesion of other and ill-defined sites
0.021 0.979 0.000
C76.7 Other ill-defined sites
0.021 0.979 0.000
C76.5 Lower limb
0.021 0.979 0.000
C76.4 Upper limb
0.021 0.979 0.000
C76.2 Abdomen
0.021 0.979 0.000
C76.1 Thorax
0.021 0.979 0.000
C76.0 Head, face and neck
0.020 0.979 0.000
E05.8 Other thyrotoxicosis
0.018 0.980 0.003
C77.2 Intra-abdominal lymph nodes
0.020 0.980 0.000
C77.0 Lymph nodes of head, face and neck
0.020 0.980 0.000
I42.9 Cardiomyopathy, unspecified
0.020 0.980 0.000
C80.9 Malignant neoplasm, unspecified
0.019 0.981 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.016 0.981 0.003
E50-E64 Other nutritional deficiencies
0.013 0.982 0.005
G36 Other acute disseminated demyelination
0.018 0.982 0.000
E83 Disorders of mineral metabolism
0.017 0.983 0.000
E83.1 Disorders of iron metabolism
0.017 0.983 0.000
E16 Other disorders of pancreatic internal secretion
0.002 0.983 0.014
E15 Nondiabetic hypoglycaemic coma
0.006 0.983 0.011
G37 Other demyelinating diseases of central nervous system
0.016 0.983 0.000
E70-E90 Metabolic disorders
0.017 0.983 0.000
C77.1 Intrathoracic lymph nodes
0.016 0.984 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.006 0.984 0.010
E45 Retarded development following protein-energy malnutrition
0.006 0.984 0.010
E43 Unspecified severe protein-energy malnutrition
0.006 0.984 0.010
E42 Marasmic kwashiorkor
0.006 0.984 0.010
E41 Nutritional marasmus
0.006 0.984 0.010
E40 Kwashiorkor
0.006 0.984 0.010
E88 Other metabolic disorders
0.016 0.984 0.000
K90-K93 Other diseases of the digestive system
0.000 0.984 0.016
E46 Unspecified protein-energy malnutrition
0.002 0.984 0.014
J38.4 Oedema of larynx
0.016 0.984 0.000
I42.8 Other cardiomyopathies
0.015 0.985 0.000
I42 Cardiomyopathy
0.015 0.985 0.000
E83.5 Disorders of calcium metabolism
0.015 0.985 0.000
G36.0 Neuromyelitis optica [Devic]
0.015 0.985 0.000
E83.3 Disorders of phosphorus metabolism
0.015 0.985 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.986 0.014
E85 Amyloidosis
0.014 0.986 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.014 0.986 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.014 0.986 0.000
E53 Deficiency of other B group vitamins
0.012 0.986 0.002
E65-E68 Obesity and other hyperalimentation
0.007 0.986 0.007
K51.9 Ulcerative colitis, unspecified
0.014 0.986 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.013 0.987 0.000
K51 Ulcerative colitis
0.013 0.987 0.000
K51.2 Ulcerative (chronic) proctitis
0.013 0.987 0.000
E79 Disorders of purine and pyrimidine metabolism
0.013 0.987 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.009 0.987 0.004
E63 Other nutritional deficiencies
0.009 0.987 0.004
E50 Vitamin A deficiency
0.009 0.987 0.004
E60 Dietary zinc deficiency
0.009 0.987 0.004
E59 Dietary selenium deficiency
0.009 0.987 0.004
E54 Ascorbic acid deficiency
0.009 0.987 0.004
E52 Niacin deficiency [pellagra]
0.009 0.987 0.004
E51 Thiamine deficiency
0.009 0.987 0.004
E56 Other vitamin deficiencies
0.009 0.987 0.004
I42.1 Obstructive hypertrophic cardiomyopathy
0.013 0.987 0.000
G36.9 Acute disseminated demyelination, unspecified
0.013 0.987 0.000
G36.8 Other specified acute disseminated demyelination
0.013 0.987 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.013 0.987 0.000
I42.6 Alcoholic cardiomyopathy
0.013 0.987 0.000
E58 Dietary calcium deficiency
0.009 0.987 0.004
E85.3 Secondary systemic amyloidosis
0.013 0.987 0.000
E74 Other disorders of carbohydrate metabolism
0.013 0.987 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.013 0.987 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.013 0.987 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.013 0.987 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.013 0.987 0.000
E83.8 Other disorders of mineral metabolism
0.013 0.987 0.000
E83.2 Disorders of zinc metabolism
0.013 0.987 0.000
E83.0 Disorders of copper metabolism
0.013 0.987 0.000
E88.3 Tumour lysis syndrome
0.013 0.987 0.000
E88.2 Lipomatosis, not elsewhere classified
0.013 0.987 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.001 0.987 0.011
E84 Cystic fibrosis
0.012 0.987 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.012 0.988 0.000
E72 Other disorders of amino-acid metabolism
0.012 0.988 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.002 0.988 0.010
E16.8 Other specified disorders of pancreatic internal secretion
0.002 0.988 0.010
E16.4 Abnormal secretion of gastrin
0.002 0.988 0.010
E16.3 Increased secretion of glucagon
0.002 0.988 0.010
E16.1 Other hypoglycaemia
0.002 0.988 0.011
G37.5 Concentric sclerosis [Balo]
0.012 0.988 0.000
G37.4 Subacute necrotising myelitis
0.012 0.988 0.000
G37.2 Central pontine myelinolysis
0.012 0.988 0.000
G37.1 Central demyelination of corpus callosum
0.012 0.988 0.000
G37.0 Diffuse sclerosis
0.012 0.988 0.000
E77 Disorders of glycoprotein metabolism
0.012 0.988 0.000
E76 Disorders of glycosaminoglycan metabolism
0.012 0.988 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.012 0.988 0.000
E70 Disorders of aromatic amino-acid metabolism
0.012 0.988 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.012 0.988 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.012 0.988 0.000
E85.8 Other amyloidosis
0.012 0.988 0.000
E89.2 Postprocedural hypoparathyroidism
0.012 0.988 0.000
E88.9 Metabolic disorder, unspecified
0.012 0.988 0.000
E44.1 Mild protein-energy malnutrition
0.004 0.988 0.008
E44.0 Moderate protein-energy malnutrition
0.004 0.988 0.008
E88.8 Other specified metabolic disorders
0.012 0.988 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.012 0.988 0.000
K51.5 Mucosal proctocolitis
0.012 0.988 0.000
E53.8 Deficiency of other specified B group vitamins
0.012 0.988 0.000
E83.4 Disorders of magnesium metabolism
0.012 0.988 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.988 0.012
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.012 0.988 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.011 0.988 0.000
E86 Volume depletion
0.011 0.989 0.000
I42.5 Other restrictive cardiomyopathy
0.011 0.989 0.000
I42.4 Endocardial fibroelastosis
0.011 0.989 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.011 0.989 0.000
C79 Secondary malignant neoplasm of other sites
0.011 0.989 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.011 0.989 0.000
E61 Deficiency of other nutrient elements
0.007 0.989 0.004
K51.1 Ulcerative (chronic) ileocolitis
0.011 0.989 0.000
E55 Vitamin D deficiency
0.008 0.989 0.003
E85.2 Heredofamilial amyloidosis, unspecified
0.010 0.990 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.010 0.990 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.010 0.990 0.000
E53.9 Vitamin B deficiency, unspecified
0.009 0.990 0.001
E73 Lactose intolerance
0.010 0.990 0.000
I42.2 Other hypertrophic cardiomyopathy
0.010 0.990 0.000
E53.1 Pyridoxine deficiency
0.009 0.990 0.002
E53.0 Riboflavin deficiency
0.009 0.990 0.002
E80.1 Porphyria cutanea tarda
0.010 0.990 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.010 0.990 0.000
E85.9 Amyloidosis, unspecified
0.010 0.990 0.000
E67 Other hyperalimentation
0.005 0.990 0.005
E68 Sequelae of hyperalimentation
0.005 0.990 0.005
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.010 0.990 0.000
E80.2 Other porphyria
0.010 0.990 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.010 0.990 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.010 0.990 0.000
E79.1 Lesch-Nyhan syndrome
0.010 0.990 0.000
E50.9 Vitamin A deficiency, unspecified
0.007 0.990 0.003
E50.8 Other manifestations of vitamin A deficiency
0.007 0.990 0.003
E50.7 Other ocular manifestations of vitamin A deficiency
0.007 0.990 0.003
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.007 0.990 0.003
E50.5 Vitamin A deficiency with night blindness
0.007 0.990 0.003
E50.4 Vitamin A deficiency with keratomalacia
0.007 0.990 0.003
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.007 0.990 0.003
E50.2 Vitamin A deficiency with corneal xerosis
0.007 0.990 0.003
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.007 0.990 0.003
E50.0 Vitamin A deficiency with conjunctival xerosis
0.007 0.990 0.003
E63.9 Nutritional deficiency, unspecified
0.007 0.990 0.003
E63.8 Other specified nutritional deficiencies
0.007 0.990 0.003
E63.1 Imbalance of constituents of food intake
0.007 0.990 0.003
E63.0 Essential fatty acid [EFA] deficiency
0.007 0.990 0.003
E64.9 Sequelae of unspecified nutritional deficiency
0.007 0.990 0.003
E64.8 Sequelae of other nutritional deficiencies
0.007 0.990 0.003
E64.3 Sequelae of rickets
0.007 0.990 0.003
E64.2 Sequelae of vitamin C deficiency
0.007 0.990 0.003
E64.1 Sequelae of vitamin A deficiency
0.007 0.990 0.003
E64.0 Sequelae of protein-energy malnutrition
0.007 0.990 0.003
E51.9 Thiamine deficiency, unspecified
0.007 0.990 0.003
E51.8 Other manifestations of thiamine deficiency
0.007 0.990 0.003
E51.1 Beriberi
0.007 0.990 0.003
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.010 0.990 0.000
E56.9 Vitamin deficiency, unspecified
0.007 0.990 0.003
E56.8 Deficiency of other vitamins
0.007 0.990 0.003
E56.0 Deficiency of vitamin E
0.007 0.990 0.003
E84.9 Cystic fibrosis, unspecified
0.009 0.990 0.000
E51.2 Wernicke's encephalopathy
0.007 0.990 0.003
E56.1 Deficiency of vitamin K
0.007 0.990 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.009 0.990 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.009 0.990 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.009 0.990 0.000
E74.2 Disorders of galactose metabolism
0.009 0.990 0.000
E74.1 Disorders of fructose metabolism
0.009 0.990 0.000
E74.0 Glycogen storage disease
0.009 0.990 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.009 0.991 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.009 0.991 0.000
E89.5 Postprocedural testicular hypofunction
0.009 0.991 0.000
E89.1 Postprocedural hypoinsulinaemia
0.009 0.991 0.000
E72.0 Disorders of amino-acid transport
0.009 0.991 0.000
E84.8 Cystic fibrosis with other manifestations
0.009 0.991 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.009 0.991 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.009 0.991 0.000
C79.2 Secondary malignant neoplasm of skin
0.009 0.991 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.009 0.991 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.009 0.991 0.000
E72.5 Disorders of glycine metabolism
0.009 0.991 0.000
E72.4 Disorders of ornithine metabolism
0.009 0.991 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.009 0.991 0.000
E72.2 Disorders of urea cycle metabolism
0.009 0.991 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.009 0.991 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.009 0.991 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.009 0.991 0.000
E70.3 Albinism
0.009 0.991 0.000
E70.2 Disorders of tyrosine metabolism
0.009 0.991 0.000
E70.1 Other hyperphenylalaninaemias
0.009 0.991 0.000
E70.0 Classical phenylketonuria
0.009 0.991 0.000
E71.3 Disorders of fatty-acid metabolism
0.009 0.991 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.009 0.991 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.009 0.991 0.000
E71.0 Maple-syrup-urine disease
0.009 0.991 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.009 0.991 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.009 0.991 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.009 0.991 0.000
E76.2 Other mucopolysaccharidoses
0.009 0.991 0.000
E76.1 Mucopolysaccharidosis, type II
0.009 0.991 0.000
E76.0 Mucopolysaccharidosis, type I
0.009 0.991 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.009 0.991 0.000
E77.8 Other disorders of glycoprotein metabolism
0.009 0.991 0.000
E77.1 Defects in glycoprotein degradation
0.009 0.991 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.009 0.991 0.000
E65 Localised adiposity
0.004 0.991 0.005
E80.7 Disorder of bilirubin metabolism, unspecified
0.009 0.991 0.000
E80.5 Crigler-Najjar syndrome
0.009 0.991 0.000
E80.3 Defects of catalase and peroxydase
0.009 0.991 0.000
E80.0 Hereditary erythropoietic porphyria
0.009 0.991 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.009 0.991 0.000
E80.6 Other disorders of bilirubin metabolism
0.009 0.991 0.000
E89.4 Postprocedural ovarian failure
0.009 0.991 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.991 0.008
K93.1 Megacolon in Chagas' disease
0.000 0.991 0.008
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.991 0.008
E75.6 Lipid storage disorder, unspecified
0.008 0.991 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.008 0.991 0.000
E75.3 Sphingolipidosis, unspecified
0.008 0.991 0.000
E75.2 Other sphingolipidosis
0.008 0.991 0.000
E75.1 Other gangliosidosis
0.008 0.991 0.000
E75.0 GM2 gangliosidosis
0.008 0.991 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.009 0.991 0.000
E89.3 Postprocedural hypopituitarism
0.008 0.992 0.000
E75.5 Other lipid storage disorders
0.008 0.992 0.000
K51.8 Other ulcerative colitis
0.008 0.992 0.000
E61.9 Deficiency of nutrient element, unspecified
0.005 0.992 0.003
E61.8 Deficiency of other specified nutrient elements
0.005 0.992 0.003
E61.7 Deficiency of multiple nutrient elements
0.005 0.992 0.003
E61.6 Vanadium deficiency
0.005 0.992 0.003
E61.5 Molybdenum deficiency
0.005 0.992 0.003
E61.4 Chromium deficiency
0.005 0.992 0.003
E61.3 Manganese deficiency
0.005 0.992 0.003
E61.0 Copper deficiency
0.005 0.992 0.003
E61.2 Magnesium deficiency
0.005 0.992 0.003
C79.7 Secondary malignant neoplasm of adrenal gland
0.008 0.992 0.000
C79.6 Secondary malignant neoplasm of ovary
0.008 0.992 0.000
E85.4 Organ-limited amyloidosis
0.008 0.992 0.000
E20-E35 Disorders of other endocrine glands
0.004 0.992 0.004
E55.0 Rickets, active
0.006 0.992 0.002
E73.8 Other lactose intolerance
0.008 0.992 0.000
E73.1 Secondary lactase deficiency
0.008 0.992 0.000
E73.0 Congenital lactase deficiency
0.008 0.992 0.000
E89.0 Postprocedural hypothyroidism
0.008 0.992 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.001 0.992 0.006
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.992 0.008
E67.8 Other specified hyperalimentation
0.004 0.992 0.004
E67.3 Hypervitaminosis D
0.004 0.992 0.004
E67.2 Megavitamin-B6 syndrome
0.004 0.992 0.004
E67.1 Hypercarotenaemia
0.004 0.992 0.004
E67.0 Hypervitaminosis A
0.004 0.992 0.004
G59.0 Diabetic mononeuropathy
0.000 0.992 0.008
I89.0 Lymphoedema, not elsewhere classified
0.007 0.993 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.007 0.993 0.000
E11.9 Without complications
0.000 0.993 0.007
K56.7 Ileus, unspecified
0.000 0.994 0.006
H50.9 Strabismus, unspecified
0.000 0.994 0.006
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.006 0.994 0.000
E73.9 Lactose intolerance, unspecified
0.006 0.994 0.000
M25.57 Pain in joint (Ankle and foot)
0.000 0.994 0.006
E31 Polyglandular dysfunction
0.003 0.994 0.003
L81.9 Disorder of pigmentation, unspecified
0.006 0.994 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.003 0.994 0.003
E32 Diseases of thymus
0.003 0.994 0.003
E30 Disorders of puberty, not elsewhere classified
0.003 0.994 0.003
E25 Adrenogenital disorders
0.003 0.994 0.003
K51.4 Pseudopolyposis of colon
0.006 0.994 0.000
H11.3 Conjunctival haemorrhage
0.006 0.994 0.000
E20 Hypoparathyroidism
0.003 0.994 0.003
E61.1 Iron deficiency
0.002 0.995 0.003
E34 Other endocrine disorders
0.003 0.995 0.002
E26 Hyperaldosteronism
0.003 0.995 0.003
N18.9 Chronic renal failure, unspecified
0.000 0.995 0.005
H11 Other disorders of conjunctiva
0.005 0.995 0.000
E24 Cushing's syndrome
0.003 0.995 0.002
E29 Testicular dysfunction
0.002 0.995 0.003
H11.0 Pterygium
0.005 0.995 0.000
E23 Hypofunction and other disorders of pituitary gland
0.001 0.995 0.004
H50 Other strabismus
0.000 0.995 0.005
D12.7 Rectosigmoid junction
0.005 0.995 0.000
E55.9 Vitamin D deficiency, unspecified
0.004 0.995 0.001
E80.4 Gilbert's syndrome
0.005 0.995 0.000
E28 Ovarian dysfunction
0.003 0.995 0.002
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.995 0.005
E22 Hyperfunction of pituitary gland
0.002 0.995 0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.003 0.995 0.001
H50.2 Vertical strabismus
0.000 0.995 0.005
E31.0 Autoimmune polyglandular failure
0.003 0.995 0.002
H50.0 Convergent concomitant strabismus
0.000 0.995 0.005
E31.9 Polyglandular dysfunction, unspecified
0.003 0.995 0.002
E31.8 Other polyglandular dysfunction
0.003 0.995 0.002
E31.1 Polyglandular hyperfunction
0.003 0.995 0.002
E25.9 Adrenogenital disorder, unspecified
0.002 0.995 0.002
E25.8 Other adrenogenital disorders
0.002 0.995 0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.002 0.995 0.002
E30.9 Disorder of puberty, unspecified
0.002 0.995 0.002
E30.8 Other disorders of puberty
0.002 0.995 0.002
E30.1 Precocious puberty
0.002 0.995 0.002
E30.0 Delayed puberty
0.002 0.995 0.002
E32.9 Disease of thymus, unspecified
0.002 0.995 0.002
E32.8 Other diseases of thymus
0.002 0.995 0.002
E32.1 Abscess of thymus
0.002 0.995 0.002
E32.0 Persistent hyperplasia of thymus
0.002 0.995 0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.002 0.995 0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.002 0.995 0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.002 0.995 0.002
Z09.0 Follow-up examination after surgery for other conditions
0.005 0.995 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.004 0.996 0.000
E23.6 Other disorders of pituitary gland
0.000 0.996 0.004
E23.2 Diabetes insipidus
0.000 0.996 0.004
E20.8 Other hypoparathyroidism
0.002 0.996 0.002
E20.1 Pseudohypoparathyroidism
0.002 0.996 0.002
E20.0 Idiopathic hypoparathyroidism
0.002 0.996 0.002
H11.2 Conjunctival scars
0.004 0.996 0.000
H50.4 Other and unspecified heterotropia
0.000 0.996 0.004
E27 Other disorders of adrenal gland
0.002 0.996 0.002
E34.5 Androgen resistance syndrome
0.003 0.996 0.002
E34.4 Constitutional tall stature
0.003 0.996 0.002
E34.3 Short stature, not elsewhere classified
0.003 0.996 0.002
E34.2 Ectopic hormone secretion, not elsewhere classified
0.003 0.996 0.002
E34.1 Other hypersecretion of intestinal hormones
0.003 0.996 0.002
E26.8 Other hyperaldosteronism
0.002 0.996 0.002
E26.1 Secondary hyperaldosteronism
0.002 0.996 0.002
E34.0 Carcinoid syndrome
0.003 0.996 0.001
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.004 0.996 0.001
H50.8 Other specified strabismus
0.000 0.996 0.004
E23.0 Hypopituitarism
0.000 0.996 0.004
N18.0 End-stage renal disease
0.000 0.996 0.004
E26.9 Hyperaldosteronism, unspecified
0.002 0.996 0.002
H11.1 Conjunctival degenerations and deposits
0.004 0.996 0.000
H50.5 Heterophoria
0.000 0.996 0.004
C79.9 Secondary malignant neoplasm, unspecified site
0.004 0.996 0.000
L89.1 Stage II decubitus ulcer
0.004 0.996 0.000
E20.9 Hypoparathyroidism, unspecified
0.002 0.996 0.002
E24.8 Other Cushing's syndrome
0.002 0.996 0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.002 0.996 0.002
E24.3 Ectopic ACTH syndrome
0.002 0.996 0.002
E24.1 Nelson's syndrome
0.002 0.996 0.002
E29.9 Testicular dysfunction, unspecified
0.002 0.996 0.002
E29.8 Other testicular dysfunction
0.002 0.996 0.002
E29.0 Testicular hyperfunction
0.002 0.996 0.002
R74.8 Abnormal levels of other serum enzymes
0.004 0.996 0.000
E34.9 Endocrine disorder, unspecified
0.003 0.996 0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.996 0.003
E23.1 Drug-induced hypopituitarism
0.001 0.996 0.003
H50.6 Mechanical strabismus
0.000 0.996 0.004
H50.3 Intermittent heterotropia
0.000 0.996 0.004
H11.9 Disorder of conjunctiva, unspecified
0.004 0.996 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.996 0.003
H11.8 Other specified disorders of conjunctiva
0.004 0.996 0.000
E24.2 Drug-induced Cushing's syndrome
0.002 0.996 0.002
E24.0 Pituitary-dependent Cushing's disease
0.002 0.996 0.002
E34.8 Other specified endocrine disorders
0.002 0.996 0.002
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.004 0.996 0.000
E28.9 Ovarian dysfunction, unspecified
0.002 0.996 0.001
E28.8 Other ovarian dysfunction
0.002 0.996 0.001
E28.1 Androgen excess
0.002 0.996 0.001
E28.0 Oestrogen excess
0.002 0.996 0.001
E26.0 Primary hyperaldosteronism
0.002 0.996 0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.000 0.996 0.004
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.000 0.996 0.004
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.000 0.996 0.004
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.000 0.996 0.004
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.000 0.996 0.004
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.000 0.996 0.004
E21.5 Disorder of parathyroid gland, unspecified
0.003 0.996 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.