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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3135365
log Bayes Factor = 229.562
Chromosome 6   position 32,389,255  (GRCh37) Explore rs3135365 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.002 0.998
I22 Subsequent myocardial infarction
0.000 0.002 0.998
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.002 0.998
E14.3 With ophthalmic complications
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
E10.5 With peripheral circulatory complications
0.000 0.002 0.998
L43 Lichen planus
0.000 0.002 0.998
J33.0 Polyp of nasal cavity
0.000 0.004 0.996
H30-H36 Disorders of choroid and retina
0.000 0.004 0.996
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.991 0.005 0.004
L43.9 Lichen planus, unspecified
0.000 0.006 0.994
M07 Psoriatic and enteropathic arthropathies
0.000 0.006 0.994
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
M35 Other systemic involvement of connective tissue
0.000 0.009 0.991
M07.3 Other psoriatic arthropathies
0.000 0.010 0.990
G37 Other demyelinating diseases of central nervous system
0.988 0.011 0.001
E06 Thyroiditis
0.000 0.012 0.988
M20-M25 Other joint disorders
0.000 0.013 0.987
G37.9 Demyelinating disease of central nervous system, unspecified
0.986 0.014 0.000
J33.8 Other polyp of sinus
0.000 0.014 0.986
H40-H42 Glaucoma
0.000 0.015 0.985
E11.1 With ketoacidosis
0.000 0.015 0.985
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.017 0.983
E06.3 Autoimmune thyroiditis
0.000 0.021 0.979
H40 Glaucoma
0.000 0.022 0.978
H40.9 Glaucoma, unspecified
0.000 0.022 0.978
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.024 0.976
E10.2 With renal complications
0.000 0.026 0.974
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.033 0.967
M06.0 Seronegative rheumatoid arthritis
0.000 0.033 0.967
M65-M68 Disorders of synovium and tendon
0.000 0.037 0.963
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.038 0.962
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.042 0.958
M65 Synovitis and tenosynovitis
0.000 0.053 0.947
I12 Hypertensive renal disease
0.000 0.054 0.946
E10.8 With unspecified complications
0.000 0.057 0.943
H34 Retinal vascular occlusions
0.000 0.062 0.938
E78.2 Mixed hyperlipidaemia
0.000 0.064 0.936
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.065 0.935
I20 Angina pectoris
0.000 0.066 0.934
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.070 0.930
M06.3 Rheumatoid nodule
0.000 0.071 0.929
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.072 0.928
Chapter VI Diseases of the nervous system
0.013 0.075 0.912
I35.0 Aortic (valve) stenosis
0.000 0.076 0.924
I12.9 Hypertensive renal disease without renal failure
0.000 0.081 0.919
E07 Other disorders of thyroid
0.000 0.083 0.917
G50-G59 Nerve, nerve root and plexus disorders
0.001 0.085 0.914
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.085 0.915
G56.0 Carpal tunnel syndrome
0.000 0.088 0.912
E11.2 With renal complications
0.000 0.089 0.911
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.089 0.910
E11.5 With peripheral circulatory complications
0.000 0.089 0.911
G56 Mononeuropathies of upper limb
0.000 0.090 0.910
G59.0 Diabetic mononeuropathy
0.000 0.092 0.908
M06.4 Inflammatory polyarthropathy
0.000 0.095 0.905
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.097 0.903
M34 Systemic sclerosis
0.000 0.105 0.895
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.106 0.894
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.106 0.894
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.002 0.107 0.892
D64.9 Anaemia, unspecified
0.000 0.107 0.893
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.108 0.892
D60-D64 Aplastic and other anaemias
0.000 0.111 0.889
D64 Other anaemias
0.000 0.111 0.889
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.116 0.884
I35 Nonrheumatic aortic valve disorders
0.000 0.119 0.881
I25 Chronic ischaemic heart disease
0.000 0.120 0.880
L43.8 Other lichen planus
0.000 0.122 0.878
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.130 0.870
E88 Other metabolic disorders
0.000 0.131 0.868
I20.9 Angina pectoris, unspecified
0.000 0.136 0.864
G63 Polyneuropathy in diseases classified elsewhere
0.001 0.139 0.860
E89.0 Postprocedural hypothyroidism
0.000 0.146 0.854
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.149 0.851
E78.1 Pure hyperglyceridaemia
0.000 0.158 0.842
Chapter VIII Diseases of the ear and mastoid process
0.000 0.158 0.842
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.159 0.841
E07.9 Disorder of thyroid, unspecified
0.000 0.159 0.841
M45-M49 Spondylopathies
0.000 0.160 0.840
G63.2 Diabetic polyneuropathy
0.000 0.163 0.837
M45 Ankylosing spondylitis
0.000 0.163 0.837
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.164 0.836
I20.0 Unstable angina
0.000 0.165 0.835
I25.1 Atherosclerotic heart disease
0.000 0.165 0.835
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.165 0.835
H43-H45 Disorders of vitreous body and globe
0.000 0.166 0.834
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.167 0.833
L40.8 Other psoriasis
0.000 0.169 0.831
I25.5 Ischaemic cardiomyopathy
0.000 0.169 0.831
I35.8 Other aortic valve disorders
0.000 0.170 0.830
H60-H62 Diseases of external ear
0.000 0.170 0.830
H34.8 Other retinal vascular occlusions
0.000 0.172 0.828
M31 Other necrotising vasculopathies
0.000 0.173 0.827
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.173 0.827
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.173 0.827
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.182 0.818
G61 Inflammatory polyneuropathy
0.001 0.184 0.816
E11.4 With neurological complications
0.000 0.185 0.815
E10.6 With other specified complications
0.000 0.185 0.815
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.186 0.814
M35.7 Hypermobility syndrome
0.000 0.192 0.807
D50-D53 Nutritional anaemias
0.000 0.193 0.807
M06.34 Rheumatoid nodule (Hand)
0.000 0.195 0.805
E03.8 Other specified hypothyroidism
0.000 0.196 0.804
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.197 0.803
H61 Other disorders of external ear
0.000 0.197 0.803
E78.6 Lipoprotein deficiency
0.000 0.204 0.796
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.204 0.796
E14.4 With neurological complications
0.000 0.205 0.795
I21 Acute myocardial infarction
0.000 0.208 0.792
H34.2 Other retinal artery occlusions
0.000 0.209 0.791
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.209 0.791
M35.2 Behcet's disease
0.000 0.210 0.790
I20.1 Angina pectoris with documented spasm
0.000 0.210 0.790
G37.8 Other specified demyelinating diseases of central nervous system
0.788 0.211 0.001
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.212 0.788
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.214 0.786
H43 Disorders of vitreous body
0.000 0.214 0.786
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.216 0.783
D50 Iron deficiency anaemia
0.000 0.217 0.783
E11.8 With unspecified complications
0.000 0.221 0.778
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.223 0.777
M35.1 Other overlap syndromes
0.000 0.227 0.773
M34.1 CR(E)ST syndrome
0.000 0.228 0.772
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.229 0.771
I05-I09 Chronic rheumatic heart diseases
0.000 0.230 0.770
H40.5 Glaucoma secondary to other eye disorders
0.000 0.230 0.770
D50.8 Other iron deficiency anaemias
0.000 0.231 0.769
M34.9 Systemic sclerosis, unspecified
0.000 0.231 0.769
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.231 0.769
H40.4 Glaucoma secondary to eye inflammation
0.000 0.232 0.768
H61.0 Perichondritis of external ear
0.000 0.232 0.768
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.232 0.768
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.233 0.767
E14.5 With peripheral circulatory complications
0.000 0.235 0.765
I35.1 Aortic (valve) insufficiency
0.000 0.241 0.759
I22.8 Subsequent myocardial infarction of other sites
0.000 0.242 0.758
M31.6 Other giant cell arteritis
0.000 0.243 0.757
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.244 0.756
E11.6 With other specified complications
0.000 0.244 0.756
G51 Facial nerve disorders
0.000 0.245 0.755
L40.0 Psoriasis vulgaris
0.000 0.246 0.754
I15 Secondary hypertension
0.000 0.246 0.754
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.247 0.753
H60 Otitis externa
0.000 0.248 0.752
I24 Other acute ischaemic heart diseases
0.000 0.251 0.749
M30 Polyarteritis nodosa and related conditions
0.000 0.251 0.749
E83 Disorders of mineral metabolism
0.486 0.251 0.263
L57.0 Actinic keratosis
0.000 0.253 0.747
E20-E35 Disorders of other endocrine glands
0.000 0.255 0.745
E74 Other disorders of carbohydrate metabolism
0.000 0.260 0.740
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.261 0.739
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.263 0.737
L80 Vitiligo
0.000 0.264 0.736
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.266 0.734
H34.1 Central retinal artery occlusion
0.000 0.267 0.733
M65.1 Other infective (teno)synovitis
0.000 0.271 0.729
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.272 0.728
G54 Nerve root and plexus disorders
0.000 0.274 0.725
M15-M19 Arthrosis
0.000 0.275 0.725
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.275 0.725
G52 Disorders of other cranial nerves
0.001 0.277 0.722
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.277 0.723
E06.9 Thyroiditis, unspecified
0.000 0.278 0.722
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.281 0.719
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.281 0.718
E14.2 Withrenal complications
0.000 0.281 0.718
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.716
E78.3 Hyperchylomicronaemia
0.000 0.283 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E70 Disorders of aromatic amino-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.715
L43.3 Subacute (active) lichen planus
0.000 0.285 0.715
L43.2 Lichenoid drug reaction
0.000 0.285 0.715
L43.1 Bullous lichen planus
0.000 0.285 0.715
L43.0 Hypertrophic lichen planus
0.000 0.285 0.715
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.285 0.715
M14 Arthropathies in other diseases classified elsewhere
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.286 0.714
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.286 0.714
G36 Other acute disseminated demyelination
0.711 0.286 0.003
E07.8 Other specified disorders of thyroid
0.000 0.287 0.713
M07.5 Arthropathy in ulcerative colitis
0.000 0.288 0.712
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.288 0.712
M07.2 Psoriatic spondylitis
0.000 0.288 0.712
M07.1 Arthritis mutilans
0.000 0.288 0.712
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.288 0.712
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.710 0.289 0.001
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.289 0.711
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.289 0.711
M35.5 Multifocal fibrosclerosis
0.000 0.289 0.711
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.289 0.711
M18 Arthrosis of first carpometacarpal joint
0.000 0.289 0.711
H40.1 Primary open-angle glaucoma
0.000 0.290 0.710
M07.38 Other psoriatic arthropathies (Other)
0.000 0.290 0.710
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.290 0.710
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.290 0.710
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.290 0.710
G37.5 Concentric sclerosis [Balo]
0.709 0.290 0.001
G37.4 Subacute necrotising myelitis
0.709 0.290 0.001
G37.2 Central pontine myelinolysis
0.709 0.290 0.001
G37.1 Central demyelination of corpus callosum
0.709 0.290 0.001
G37.0 Diffuse sclerosis
0.709 0.290 0.001
E16.1 Other hypoglycaemia
0.000 0.291 0.709
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.291 0.709
G61.0 Guillain-Barre syndrome
0.000 0.291 0.709
E06.5 Other chronic thyroiditis
0.000 0.292 0.708
E06.4 Drug-induced thyroiditis
0.000 0.292 0.708
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.292 0.708
E06.1 Subacute thyroiditis
0.000 0.292 0.708
E06.0 Acute thyroiditis
0.000 0.292 0.708
E89.2 Postprocedural hypoparathyroidism
0.000 0.292 0.708
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.292 0.708
H42 Glaucoma in diseases classified elsewhere
0.000 0.293 0.706
I21.9 Acute myocardial infarction, unspecified
0.000 0.294 0.706
H43.3 Other vitreous opacities
0.000 0.297 0.703
L85 Other epidermal thickening
0.000 0.299 0.701
H40.6 Glaucoma secondary to drugs
0.000 0.299 0.701
H40.3 Glaucoma secondary to eye trauma
0.000 0.299 0.701
H30 Chorioretinal inflammation
0.000 0.299 0.701
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.300 0.700
G61.8 Other inflammatory polyneuropathies
0.000 0.302 0.698
H34.9 Retinal vascular occlusion, unspecified
0.000 0.302 0.698
G60 Hereditary and idiopathic neuropathy
0.001 0.302 0.697
I00-I02 Acute rheumatic fever
0.000 0.303 0.696
G56.8 Other mononeuropathies of upper limb
0.000 0.304 0.696
G53 Cranial nerve disorders in diseases classified elsewhere
0.001 0.305 0.695
E13 Other specified diabetes mellitus
0.000 0.306 0.694
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.307 0.693
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.307 0.693
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.307 0.693
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.307 0.693
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.307 0.693
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.307 0.693
M12 Other specific arthropathies
0.000 0.310 0.690
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.310 0.690
H61.8 Other specified disorders of external ear
0.000 0.312 0.688
J30-J39 Other diseases of upper respiratory tract
0.000 0.312 0.688
Chapter X Diseases of the respiratory system
0.000 0.312 0.688
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.317 0.683
E40-E46 Malnutrition
0.000 0.319 0.681
E73 Lactose intolerance
0.000 0.319 0.681
E79 Disorders of purine and pyrimidine metabolism
0.000 0.320 0.680
E11.0 With coma
0.000 0.320 0.679
M24 Other specific joint derangements
0.000 0.321 0.679
M65.2 Calcific tendinitis
0.000 0.321 0.679
M65.0 Abscess of tendon sheath
0.000 0.321 0.679
H61.1 Non-infective disorders of pinna
0.000 0.321 0.679
E88.8 Other specified metabolic disorders
0.000 0.321 0.679
D50.9 Iron deficiency anaemia, unspecified
0.000 0.323 0.677
E84 Cystic fibrosis
0.000 0.324 0.676
H34.0 Transient retinal artery occlusion
0.000 0.328 0.672
L85.8 Other specified epidermal thickening
0.000 0.329 0.671
I11 Hypertensive heart disease
0.000 0.330 0.669
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.333 0.667
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.334 0.666
M06.38 Rheumatoid nodule (Other)
0.000 0.334 0.666
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.334 0.666
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.334 0.666
M06.33 Rheumatoid nodule (Forearm)
0.000 0.334 0.666
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.334 0.666
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.334 0.666
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.334 0.666
L10-L14 Bullous disorders
0.000 0.336 0.663
E89.4 Postprocedural ovarian failure
0.000 0.337 0.663
M11 Other crystal arthropathies
0.000 0.337 0.663
M07.6 Other enteropathic arthropathies
0.000 0.339 0.660
E07.1 Dyshormogenetic goitre
0.000 0.343 0.657
E07.0 Hypersecretion of calcitonin
0.000 0.343 0.657
E72 Other disorders of amino-acid metabolism
0.000 0.346 0.654
G59.8 Other mononeuropathies in diseases classified elsewhere
0.000 0.347 0.653
E28 Ovarian dysfunction
0.000 0.347 0.653
G56.4 Causalgia
0.000 0.347 0.653
H35 Other retinal disorders
0.000 0.348 0.652
I05 Rheumatic mitral valve diseases
0.000 0.348 0.651
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.349 0.651
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.351 0.649
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.351 0.649
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.351 0.649
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.351 0.649
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.351 0.649
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.351 0.649
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.351 0.649
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.351 0.649
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.351 0.649
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.352 0.648
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.352 0.648
E89.5 Postprocedural testicular hypofunction
0.000 0.352 0.648
E89.1 Postprocedural hypoinsulinaemia
0.000 0.352 0.648
H40.0 Glaucoma suspect
0.000 0.352 0.648
J32 Chronic sinusitis
0.000 0.353 0.647
E88.2 Lipomatosis, not elsewhere classified
0.000 0.353 0.647
E23 Hypofunction and other disorders of pituitary gland
0.000 0.355 0.645
H60.3 Other infective otitis externa
0.000 0.355 0.645
M60-M63 Disorders of muscles
0.000 0.356 0.644
I23 Certain current complications following acute myocardial infarction
0.000 0.356 0.644
L42 Pityriasis rosea
0.000 0.356 0.644
L94 Other localised connective tissue disorders
0.000 0.356 0.644
E05.8 Other thyrotoxicosis
0.000 0.357 0.643
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.358 0.642
M34.0 Progressive systemic sclerosis
0.000 0.358 0.642
M10 Gout
0.000 0.358 0.642
G64 Other disorders of peripheral nervous system
0.001 0.359 0.639
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.361 0.639
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.361 0.639
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.361 0.639
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.361 0.639
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.361 0.639
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.361 0.639
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.361 0.639
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.361 0.639
E88.3 Tumour lysis syndrome
0.000 0.361 0.638
M80-M85 Disorders of bone density and structure
0.000 0.362 0.638
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.362 0.638
D64.4 Congenital dyserythropoietic anaemia
0.000 0.363 0.637
D64.3 Other sideroblastic anaemias
0.000 0.363 0.637
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.363 0.637
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.363 0.637
D64.0 Hereditary sideroblastic anaemia
0.000 0.363 0.637
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.364 0.635
H60.1 Cellulitis of external ear
0.000 0.364 0.635
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.366 0.634
H35.8 Other specified retinal disorders
0.000 0.366 0.634
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.366 0.634
M66 Spontaneous rupture of synovium and tendon
0.000 0.367 0.633
I25.6 Silent myocardial ischaemia
0.000 0.369 0.631
M49 Spondylopathies in diseases classified elsewhere
0.000 0.370 0.630
G51.0 Bell's palsy
0.000 0.370 0.630
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.370 0.629
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.373 0.627
H43.8 Other disorders of vitreous body
0.000 0.375 0.625
M34.8 Other forms of systemic sclerosis
0.000 0.375 0.625
E88.9 Metabolic disorder, unspecified
0.000 0.377 0.623
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.377 0.623
D61 Other aplastic anaemias
0.000 0.378 0.622
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.379 0.621
D53 Other nutritional anaemias
0.000 0.380 0.620
I09 Other rheumatic heart diseases
0.000 0.381 0.619
G63.8 Polyneuropathy in other diseases classified elsewhere
0.001 0.383 0.616
G63.6 Polyneuropathy in other musculoskeletal disorders
0.001 0.383 0.616
G63.5 Polyneuropathy in systemic connective tissue disorders
0.001 0.383 0.616
G63.4 Polyneuropathy in nutritional deficiency
0.001 0.383 0.616
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.001 0.383 0.616
G63.1 Polyneuropathy in neoplastic disease
0.001 0.383 0.616
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.001 0.383 0.616
H43.2 Crystalline deposits in vitreous body
0.000 0.383 0.617
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.384 0.616
M91-M94 Chondropathies
0.000 0.386 0.614
M31.3 Wegener's granulomatosis
0.000 0.387 0.613
M32 Systemic lupus erythematosus
0.000 0.388 0.612
E03.1 Congenital hypothyroidism without goitre
0.000 0.388 0.612
G70-G73 Diseases of myoneural junction and muscle
0.006 0.388 0.605
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.389 0.611
E29 Testicular dysfunction
0.000 0.391 0.609
H43.9 Disorder of vitreous body, unspecified
0.000 0.393 0.607
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.394 0.606
E78.8 Other disorders of lipoprotein metabolism
0.000 0.394 0.606
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.394 0.606
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.395 0.605
G54.6 Phantom limb syndrome with pain
0.000 0.396 0.603
G51.9 Disorder of facial nerve, unspecified
0.000 0.397 0.603
L92.0 Granuloma annulare
0.000 0.398 0.602
H60.4 Cholesteatoma of external ear
0.000 0.398 0.601
I24.8 Other forms of acute ischaemic heart disease
0.000 0.399 0.601
J32.9 Chronic sinusitis, unspecified
0.000 0.399 0.601
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.400 0.600
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.400 0.600
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.400 0.600
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.400 0.600
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.400 0.600
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.400 0.600
G60.0 Hereditary motor and sensory neuropathy
0.000 0.401 0.598
L55 Sunburn
0.000 0.402 0.598
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.402 0.598
I25.2 Old myocardial infarction
0.000 0.402 0.598
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.405 0.595
G56.1 Other lesions of median nerve
0.000 0.406 0.594
M31.8 Other specified necrotising vasculopathies
0.000 0.407 0.593
M31.7 Microscopic polyangiitis
0.000 0.407 0.593
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.407 0.593
M31.2 Lethal midline granuloma
0.000 0.407 0.593
I15.9 Seconday hypertension, unspecified
0.000 0.409 0.591
M24.1 Other articular cartilage disorders
0.000 0.410 0.590
M31.1 Thrombotic microangiopathy
0.000 0.411 0.589
G56.3 Lesion of radial nerve
0.000 0.411 0.588
M15 Polyarthrosis
0.000 0.412 0.588
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.413 0.587
M67 Other disorders of synovium and tendon
0.000 0.414 0.586
I05.9 Mitral valve disease, unspecified
0.000 0.414 0.586
G61.9 Inflammatory polyneuropathy, unspecified
0.001 0.415 0.585
G61.1 Serum neuropathy
0.001 0.415 0.585
H60.9 Otitis externa, unspecified
0.000 0.417 0.583
M80 Osteoporosis with pathological fracture
0.000 0.417 0.583
H55-H59 Other disorders of eye and adnexa
0.000 0.418 0.582
E28.3 Primary ovarian failure
0.000 0.418 0.581

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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