TreeWAS – Variant ID: rs3135392

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	1.000	0.000	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
C83.3 Large cell (diffuse)	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
C83 Diffuse non-Hodgkin's lymphoma	1.000	0.000	0.000
C44.3 Skin of other and unspecified parts of face	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.998	0.002	0.000
E10-E14 Diabetes mellitus	0.998	0.002	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.998	0.002	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.997	0.003	0.000
C44.2 Skin of ear and external auricular canal	0.992	0.008	0.000
L40 Psoriasis	0.991	0.009	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.990	0.010	0.000
L40-L45 Papulosquamous disorders	0.986	0.014	0.000
E10.1 With ketoacidosis	0.984	0.016	0.000
E10.9 Without complications	0.980	0.020	0.000
C44.6 Skin of upper limb, including shoulder	0.972	0.028	0.000
C44.4 Skin of scalp and neck	0.970	0.030	0.000
L43 Lichen planus	0.968	0.032	0.000
C44.7 Skin of lower limb, including hip	0.966	0.034	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.965	0.035	0.000
C85.1 B-cell lymphoma, unspecified	0.965	0.035	0.000
Chapter II Neoplasms	0.956	0.044	0.000
L43.9 Lichen planus, unspecified	0.953	0.047	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.952	0.048	0.000
E10.2 With renal complications	0.941	0.059	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.939	0.061	0.000
E10.3 With ophthalmic complications	0.928	0.072	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.926	0.074	0.000
# Top node	0.923	0.077	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.910	0.090	0.000
E20-E35 Disorders of other endocrine glands	0.908	0.092	0.000
K90 Intestinal malabsorption	0.903	0.097	0.000
H00.1 Chalazion	0.000	0.100	0.900
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.895	0.105	0.000
Q60-Q64 Congenital malformations of the urinary system	0.888	0.112	0.000
E28 Ovarian dysfunction	0.878	0.122	0.000
C02.9 Tongue, unspecified	0.878	0.122	0.000
E40-E46 Malnutrition	0.871	0.129	0.000
E14 Unspecified diabetes mellitus	0.870	0.130	0.000
D60-D64 Aplastic and other anaemias	0.870	0.130	0.000
Q61 Cystic kidney disease	0.869	0.131	0.000
D55-D59 Haemolytic anaemias	0.861	0.139	0.000
L40.9 Psoriasis, unspecified	0.858	0.142	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.856	0.144	0.000
C82.2 Large cell, follicular	0.854	0.146	0.000
C82.0 Small cleaved cell, follicular	0.852	0.148	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.849	0.151	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.848	0.152	0.000
D61 Other aplastic anaemias	0.845	0.155	0.000
L50-L54 Urticaria and erythema	0.844	0.156	0.000
C02.1 Border of tongue	0.843	0.157	0.000
C44.0 Skin of lip	0.841	0.159	0.000
Q61.3 Polycystic kidney, unspecified	0.840	0.160	0.000
K52 Other non-infective gastro-enteritis and colitis	0.828	0.172	0.000
K50-K52 Noninfective enteritis and colitis	0.825	0.175	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.822	0.178	0.000
K90-K93 Other diseases of the digestive system	0.820	0.180	0.000
D61.9 Aplastic anaemia, unspecified	0.819	0.181	0.000
E28.3 Primary ovarian failure	0.817	0.183	0.000
Chapter XI Diseases of the digestive system	0.817	0.183	0.000
C04 Malignant neoplasm of floor of mouth	0.814	0.186	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.813	0.187	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.198	0.802
E10.4 With neurological complications	0.800	0.200	0.000
C83.2 Mixed small and large cell (diffuse)	0.798	0.202	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.794	0.206	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.794	0.206	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.208	0.792
Q60.2 Renal agenesis, unspecified	0.792	0.208	0.000
E28.2 Polycystic ovarian syndrome	0.790	0.210	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.789	0.211	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.785	0.215	0.000
E46 Unspecified protein-energy malnutrition	0.780	0.220	0.000
L43.0 Hypertrophic lichen planus	0.777	0.223	0.000
H00 Hordeolum and chalazion	0.000	0.225	0.775
L40.3 Pustulosis palmaris et plantaris	0.775	0.225	0.000
C83.1 Small cleaved cell (diffuse)	0.775	0.225	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.772	0.228	0.000
D56 Thalassaemia	0.770	0.230	0.000
Q60.0 Renal agenesis, unilateral	0.770	0.230	0.000
E10.5 With peripheral circulatory complications	0.769	0.231	0.000
K90.9 Intestinal malabsorption, unspecified	0.769	0.231	0.000
E10.7 With multiple complications	0.767	0.233	0.000
L51 Erythema multiforme	0.766	0.233	0.000
E06 Thyroiditis	0.765	0.235	0.000
C12 Malignant neoplasm of pyriform sinus	0.765	0.235	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.237	0.763
L52 Erythema nodosum	0.762	0.238	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.759	0.241	0.000
Q43 Other congenital malformations of intestine	0.756	0.244	0.000
C02.8 Overlapping lesion of tongue	0.751	0.249	0.000
C13 Malignant neoplasm of hypopharynx	0.750	0.250	0.000
E10.0 With coma	0.750	0.250	0.000
E23 Hypofunction and other disorders of pituitary gland	0.750	0.250	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.250	0.750
E07 Other disorders of thyroid	0.748	0.252	0.000
C88 Malignant immunoproliferative diseases	0.748	0.252	0.000
K50 Crohn's disease [regional enteritis]	0.744	0.256	0.000
D58 Other hereditary haemolytic anaemias	0.741	0.259	0.000
E10.8 With unspecified complications	0.738	0.262	0.000
L44 Other papulosquamous disorders	0.735	0.265	0.000
K50.1 Crohn's disease of large intestine	0.734	0.266	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.734	0.266	0.000
Q61.9 Cystic kidney disease, unspecified	0.734	0.266	0.000
C84.5 Other and unspecified T-cell lymphomas	0.734	0.266	0.000
C10 Malignant neoplasm of oropharynx	0.733	0.267	0.000
M05 Seropositive rheumatoid arthritis	0.001	0.269	0.731
C90 Multiple myeloma and malignant plasma cell neoplasms	0.731	0.269	0.000
D62 Acute posthaemorrhagic anaemia	0.729	0.271	0.000
K52.3 Indeterminate colitis	0.728	0.272	0.000
C83.7 Burkitt's tumour	0.725	0.275	0.000
E26 Hyperaldosteronism	0.725	0.275	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.721	0.279	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.720	0.280	0.000
C95 Leukaemia of unspecified cell type	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C94 Other leukaemias of specified cell type	0.717	0.283	0.000
C85.0 Lymphosarcoma	0.717	0.283	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
C83.6 Undifferentiated (diffuse)	0.717	0.283	0.000
C83.5 Lymphoblastic (diffuse)	0.717	0.283	0.000
C83.4 Immunoblastic (diffuse)	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.284	0.000
E12 Malnutrition-related diabetes mellitus	0.715	0.284	0.000
E14.3 With ophthalmic complications	0.715	0.285	0.000
C82.6 Cutaneous follicle centre lymphoma	0.715	0.285	0.000
C82.5 Diffuse follicle centre lymphoma	0.715	0.285	0.000
C02.2 Ventral surface of tongue	0.714	0.286	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.713	0.287	0.000
L42 Pityriasis rosea	0.713	0.287	0.000
L40.1 Generalised pustular psoriasis	0.712	0.288	0.000
L40.2 Acrodermatitis continua	0.711	0.289	0.000
C05 Malignant neoplasm of palate	0.710	0.290	0.000
E14.8 With unspecified complications	0.709	0.291	0.000
L41 Parapsoriasis	0.707	0.293	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.707	0.293	0.000
L51.9 Erythema multiforme, unspecified	0.706	0.294	0.000
C03 Malignant neoplasm of gum	0.704	0.296	0.000
Q00-Q07 Congenital malformations of the nervous system	0.701	0.299	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.701	0.299	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.304	0.696
E14.5 With peripheral circulatory complications	0.695	0.305	0.000
L43.3 Subacute (active) lichen planus	0.694	0.306	0.000
L43.2 Lichenoid drug reaction	0.694	0.306	0.000
L43.1 Bullous lichen planus	0.694	0.306	0.000
L10-L14 Bullous disorders	0.693	0.307	0.000
C82.4 Follicular lymphoma grade IIIb	0.692	0.308	0.000
M06 Other rheumatoid arthritis	0.000	0.308	0.692
C81 Hodgkin's disease	0.689	0.311	0.000
D61.1 Drug-induced aplastic anaemia	0.689	0.311	0.000
D80-D89 Certain disorders involving the immune mechanism	0.688	0.312	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.685	0.315	0.000
E14.4 With neurological complications	0.684	0.315	0.000
Q50-Q56 Congenital malformations of genital organs	0.684	0.316	0.000
E14.1 With ketoacidosis	0.684	0.316	0.000
E31 Polyglandular dysfunction	0.683	0.317	0.000
L40.4 Guttate psoriasis	0.682	0.318	0.000
C07 Malignant neoplasm of parotid gland	0.681	0.319	0.000
D56.1 Beta thalassaemia	0.679	0.321	0.000
M05-M14 Inflammatory polyarthropathies	0.001	0.322	0.677
C74 Malignant neoplasm of adrenal gland	0.677	0.323	0.000
C04.9 Floor of mouth, unspecified	0.675	0.324	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.325	0.675
C02.0 Dorsal surface of tongue	0.674	0.326	0.000
C91 Lymphoid leukaemia	0.673	0.327	0.000
C82.3 Follicular lymphoma grade IIIa	0.673	0.327	0.000
E07.8 Other specified disorders of thyroid	0.671	0.329	0.000
D59 Acquired haemolytic anaemia	0.670	0.329	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.333	0.667
C11 Malignant neoplasm of nasopharynx	0.665	0.335	0.000
C73 Malignant neoplasm of thyroid gland	0.657	0.343	0.000
M06.3 Rheumatoid nodule	0.000	0.344	0.656
C85.7 Other specified types of non-Hodgkin's lymphoma	0.655	0.344	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.655	0.345	0.000
G35 Multiple sclerosis	0.000	0.346	0.654
C44.9 Malignant neoplasm of skin, unspecified	0.652	0.348	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.652	0.348	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.651	0.349	0.000
E32 Diseases of thymus	0.651	0.349	0.000
E30 Disorders of puberty, not elsewhere classified	0.651	0.349	0.000
C86 Other specified types of T/NK-cell lymphoma	0.651	0.349	0.000
C04.0 Anterior floor of mouth	0.650	0.350	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.649	0.351	0.000
K90.3 Pancreatic steatorrhoea	0.648	0.352	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.648	0.352	0.000
K90.1 Tropical sprue	0.648	0.352	0.000
Q61.2 Polycystic kidney, adult type	0.648	0.352	0.000
Q35-Q37 Cleft lip and cleft palate	0.647	0.353	0.000
Q61.5 Medullary cystic kidney	0.645	0.354	0.000
C00 Malignant neoplasm of lip	0.645	0.355	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.643	0.357	0.000
C06.0 Cheek mucosa	0.643	0.357	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.642	0.358	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.637	0.363	0.000
E06.3 Autoimmune thyroiditis	0.637	0.363	0.000
D64 Other anaemias	0.637	0.363	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.636	0.364	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.367	0.633
C82.1 Mixed small cleaved and large cell, follicular	0.632	0.368	0.000
Q61.0 Congenital single renal cyst	0.632	0.368	0.000
C84.0 Mycosis fungoides	0.631	0.369	0.000
E28.9 Ovarian dysfunction, unspecified	0.629	0.370	0.000
E28.8 Other ovarian dysfunction	0.629	0.370	0.000
E28.1 Androgen excess	0.629	0.370	0.000
E28.0 Oestrogen excess	0.629	0.370	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.627	0.373	0.000
E25 Adrenogenital disorders	0.625	0.375	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.624	0.376	0.000
E45 Retarded development following protein-energy malnutrition	0.624	0.376	0.000
E43 Unspecified severe protein-energy malnutrition	0.624	0.376	0.000
E42 Marasmic kwashiorkor	0.624	0.376	0.000
E41 Nutritional marasmus	0.624	0.376	0.000
E40 Kwashiorkor	0.624	0.376	0.000
L43.8 Other lichen planus	0.624	0.376	0.000
E14.7 With multiple complications	0.624	0.376	0.000
E14.0 With coma	0.624	0.376	0.000
Q61.8 Other cystic kidney diseases	0.623	0.377	0.000
Q61.1 Polycystic kidney, infantile type	0.623	0.377	0.000
E29 Testicular dysfunction	0.623	0.377	0.000
Q43.1 Hirschsprung's disease	0.623	0.377	0.000
C02.4 Lingual tonsil	0.621	0.378	0.000
D73 Diseases of spleen	0.621	0.379	0.000
E34 Other endocrine disorders	0.617	0.383	0.000
D57 Sickle-cell disorders	0.617	0.383	0.000
D55 Anaemia due to enzyme disorders	0.617	0.383	0.000
E14.2 Withrenal complications	0.616	0.384	0.000
E23.2 Diabetes insipidus	0.616	0.384	0.000
D70 Agranulocytosis	0.616	0.384	0.000
Q60.6 Potter's syndrome	0.614	0.386	0.000
Q60.5 Renal hypoplasia, unspecified	0.614	0.386	0.000
Q60.4 Renal hypoplasia, bilateral	0.614	0.386	0.000
Q60.3 Renal hypoplasia, unilateral	0.614	0.386	0.000
Q60.1 Renal agenesis, bilateral	0.614	0.386	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.614	0.386	0.000
Q40 Other congenital malformations of upper alimentary tract	0.613	0.387	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.612	0.387	0.000
D56.3 Thalassaemia trait	0.612	0.387	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.612	0.388	0.000
E23.6 Other disorders of pituitary gland	0.611	0.388	0.000
C83.0 Small cell (diffuse)	0.611	0.389	0.000
C01 Malignant neoplasm of base of tongue	0.610	0.389	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.609	0.391	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.609	0.391	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.609	0.391	0.000
C84.3 Lymphoepithelioid lymphoma	0.609	0.391	0.000
C84.2 T-zone lymphoma	0.609	0.391	0.000
C84.1 Sezary's diease	0.609	0.391	0.000
E20 Hypoparathyroidism	0.608	0.392	0.000
D61.0 Constitutional aplastic anaemia	0.608	0.392	0.000
D61.8 Other specified aplastic anaemias	0.606	0.394	0.000
D61.3 Idiopathic aplastic anaemia	0.606	0.394	0.000
D61.2 Aplastic anaemia due to other external agents	0.606	0.394	0.000
L53 Other erythematous conditions	0.606	0.394	0.000
E22 Hyperfunction of pituitary gland	0.606	0.394	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.395	0.605
L54 Erythema in diseases classified elsewhere	0.605	0.395	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.605	0.395	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.604	0.396	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.604	0.396	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.604	0.396	0.000
Q43.0 Meckel's diverticulum	0.603	0.397	0.000
C90.3 Solitary plasmacytoma	0.601	0.399	0.000
Q61.4 Renal dysplasia	0.599	0.401	0.000
D68 Other coagulation defects	0.599	0.401	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.598	0.402	0.000
C06.2 Retromolar area	0.592	0.408	0.000
C95.0 Acute leukaemia of unspecified cell type	0.590	0.410	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.590	0.410	0.000
C06.9 Mouth, unspecified	0.588	0.412	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.588	0.412	0.000
C91.9 Lymphoid leukaemia, unspecified	0.584	0.415	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.416	0.584
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.416	0.584
D69 Purpura and other haemorrhagic conditions	0.584	0.416	0.000
C04.8 Overlapping lesion of floor of mouth	0.584	0.416	0.000
C04.1 Lateral floor of mouth	0.584	0.416	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.583	0.417	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.583	0.417	0.000
Q39 Congenital malformations of oesophagus	0.581	0.419	0.000
Q64 Other congenital malformations of urinary system	0.581	0.419	0.000
C13.0 Postcricoid region	0.580	0.420	0.000
Q03 Congenital hydrocephalus	0.578	0.422	0.000
C10.9 Oropharynx, unspecified	0.577	0.423	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.426	0.574
E14.6 With other specified complications	0.574	0.426	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.426	0.573
E24 Cushing's syndrome	0.573	0.427	0.000
C13.9 Hypopharynx, unspecified	0.571	0.429	0.000
C05.0 Hard palate	0.570	0.430	0.000
E23.7 Disorder of pituitary gland, unspecified	0.570	0.430	0.000
L40.8 Other psoriasis	0.569	0.431	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.431	0.569
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.431	0.569
C81.1 Nodular sclerosis	0.569	0.431	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.569	0.431	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.432	0.568
L51.1 Bullous erythema multiforme	0.568	0.432	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.432	0.568
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.432	0.568
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.432	0.568
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.432	0.568
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.568	0.432	0.000
C91.5 Adult T-cell leukaemia	0.566	0.434	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.566	0.434	0.000
C06.1 Vestibule of mouth	0.566	0.434	0.000
L13 Other bullous disorders	0.565	0.434	0.000
C93 Monocytic leukaemia	0.565	0.435	0.001
D58.0 Hereditary spherocytosis	0.564	0.436	0.000
E06.9 Thyroiditis, unspecified	0.564	0.436	0.000
D73.5 Infarction of spleen	0.564	0.436	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.438	0.562
E26.9 Hyperaldosteronism, unspecified	0.561	0.439	0.000
C84.4 Peripheral T-cell lymphoma	0.560	0.440	0.000
E26.0 Primary hyperaldosteronism	0.560	0.440	0.000
E10.6 With other specified complications	0.557	0.443	0.000
K90.8 Other intestinal malabsorption	0.557	0.443	0.000
C08.0 Submandibular gland	0.557	0.443	0.000
L44.0 Pityriasis rubra pilaris	0.554	0.445	0.000
Q55 Other congenital malformations of male genital organs	0.553	0.446	0.000
D68.6 Other Thrombophilia	0.553	0.447	0.000
C74.9 Adrenal gland, unspecified	0.552	0.448	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.552	0.448	0.000
D56.9 Thalassaemia, unspecified	0.552	0.448	0.000
D56.8 Other thalassaemias	0.552	0.448	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.552	0.448	0.000
D56.2 Delta-beta thalassaemia	0.552	0.448	0.000
D56.0 Alpha thalassaemia	0.552	0.448	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.448	0.552
Q30 Congenital malformations of nose	0.550	0.450	0.000
L51.8 Other erythema multiforme	0.550	0.450	0.000
L51.2 Toxic epidermal necrolysis [Lyell]	0.550	0.450	0.000
L51.0 Nonbullous erythema multiforme	0.550	0.450	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.549	0.451	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.549	0.451	0.000
E06.4 Drug-induced thyroiditis	0.549	0.451	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.549	0.451	0.000
E06.1 Subacute thyroiditis	0.549	0.451	0.000
E06.0 Acute thyroiditis	0.549	0.451	0.000
L57.0 Actinic keratosis	0.548	0.452	0.000
Q43.3 Congenital malformations of intestinal fixation	0.547	0.452	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.545	0.455	0.000
L58 Radiodermatitis	0.544	0.456	0.000
L55 Sunburn	0.544	0.456	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.015	0.458	0.527
D59.9 Acquired haemolytic anaemia, unspecified	0.542	0.458	0.000
Q43.7 Persistent cloaca	0.542	0.458	0.000
Q43.6 Congenital fistula of rectum and anus	0.542	0.458	0.000
Q43.5 Ectopic anus	0.542	0.458	0.000
Q43.4 Duplication of intestine	0.542	0.458	0.000
Q43.2 Other congenital functional disorders of colon	0.542	0.458	0.000
K51 Ulcerative colitis	0.541	0.459	0.000
Q07 Other congenital malformations of nervous system	0.541	0.459	0.000
E34.8 Other specified endocrine disorders	0.541	0.459	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.461	0.539
C90.1 Plasma cell leukaemia	0.539	0.461	0.000
C13.8 Overlapping lesion of hypopharynx	0.538	0.462	0.000
C13.2 Posterior wall of hypopharynx	0.538	0.462	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.538	0.462	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.538	0.462	0.000
E23.1 Drug-induced hypopituitarism	0.538	0.462	0.000
E07.1 Dyshormogenetic goitre	0.536	0.463	0.000
E07.0 Hypersecretion of calcitonin	0.536	0.463	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.536	0.463	0.000
C88.7 Other malignant immunoproliferative diseases	0.536	0.463	0.000
C88.3 Immunoproliferative small intestinal disease	0.536	0.463	0.000
C88.2 Gamma heavy chain disease	0.536	0.463	0.000
C88.1 Alpha heavy chain disease	0.536	0.463	0.000
D83 Common variable immunodeficiency	0.536	0.464	0.000
D58.2 Other haemoglobinopathies	0.536	0.464	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.536	0.464	0.000
C74.0 Cortex of adrenal gland	0.535	0.465	0.000
E13 Other specified diabetes mellitus	0.534	0.465	0.000
E05.8 Other thyrotoxicosis	0.534	0.465	0.000
K50.8 Other Crohn's disease	0.534	0.466	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.534	0.466	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.531	0.469	0.000
D58.1 Hereditary elliptocytosis	0.531	0.469	0.000
E22.0 Acromegaly and pituitary gigantism	0.531	0.469	0.000
C90.0 Multiple myeloma	0.531	0.469	0.000
D73.0 Hyposplenism	0.530	0.470	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.530	0.470	0.000
C09 Malignant neoplasm of tonsil	0.530	0.470	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.471	0.529
Q45 Other congenital malformations of digestive system	0.529	0.471	0.000
L44.9 Papulosquamous disorder, unspecified	0.527	0.473	0.000
L44.8 Other specified papulosquamous disorders	0.527	0.473	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.527	0.473	0.000
L44.3 Lichen ruber moniliformis	0.527	0.473	0.000
L44.2 Lichen striatus	0.527	0.473	0.000
L44.1 Lichen nitidus	0.527	0.473	0.000
D67 Hereditary factor IX deficiency	0.526	0.474	0.000
C03.1 Lower gum	0.526	0.474	0.000
C10.8 Overlapping lesion of oropharynx	0.526	0.474	0.000
C10.4 Branchial cleft	0.526	0.474	0.000
C10.3 Posterior wall of oropharynx	0.526	0.474	0.000
C10.2 Lateral wall of oropharynx	0.526	0.474	0.000
C10.1 Anterior surface of epiglottis	0.526	0.474	0.000
C10.0 Vallecula	0.526	0.474	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.476	0.524
M05.2 Rheumatoid vasculitis	0.001	0.476	0.524
M05.1 Rheumatoid lung disease	0.001	0.476	0.524
M05.0 Felty's syndrome	0.001	0.476	0.524
E31.0 Autoimmune polyglandular failure	0.521	0.479	0.000
M12 Other specific arthropathies	0.001	0.480	0.519
E26.8 Other hyperaldosteronism	0.520	0.480	0.000
E26.1 Secondary hyperaldosteronism	0.520	0.480	0.000
Q31 Congenital malformations of larynx	0.519	0.481	0.000
D69.2 Other nonthrombocytopenic purpura	0.518	0.482	0.000
Q53 Undescended testicle	0.517	0.483	0.000
D74 Methaemoglobinaemia	0.516	0.484	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.516	0.484	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.516	0.484	0.000
Q63 Other congenital malformations of kidney	0.516	0.484	0.000
C95.7 Other leukaemia of unspecified cell type	0.514	0.486	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.514	0.486	0.000
C94.7 Other specified leukaemias	0.514	0.486	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.514	0.486	0.000
C94.5 Acute myelofibrosis	0.514	0.486	0.000
C94.4 Acute panmyelosis	0.514	0.486	0.000
C94.3 Mast cell leukaemia	0.514	0.486	0.000
C94.2 Acute megakaryoblastic leukaemia	0.514	0.486	0.000
C94.1 Chronic erythraemia	0.514	0.486	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.514	0.486	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.514	0.486	0.000
C96.8 Histiocytic sarcoma	0.514	0.486	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.514	0.486	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.514	0.486	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.514	0.486	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.514	0.486	0.000
C96.3 True histiocytic lymphoma	0.514	0.486	0.000
C96.2 Malignant mast cell tumour	0.514	0.486	0.000
C96.1 Malignant histiocytosis	0.514	0.486	0.000
C96.0 Letterer-Siwe disease	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.513	0.487	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.513	0.487	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.513	0.487	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.513	0.487	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.513	0.487	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.513	0.487	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.513	0.487	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.513	0.487	0.000
E12.9 Without complications	0.513	0.487	0.000
E12.8 With unspecified complications	0.513	0.487	0.000
E12.7 With multiple complications	0.513	0.487	0.000
E12.6 With other specified complications	0.513	0.487	0.000
E12.5 With peripheral circulatory complications	0.513	0.487	0.000
E12.4 With neurological complications	0.513	0.487	0.000
E12.3 With ophthalmic complications	0.513	0.487	0.000
E12.2 With renal complications	0.513	0.487	0.000
E12.1 With ketoacidosis	0.513	0.487	0.000
E12.0 With coma	0.513	0.487	0.000
Q52 Other congenital malformations of female genitalia	0.512	0.488	0.000
D80 Immunodeficiency with predominantly antibody defects	0.512	0.488	0.000
C08.8 Overlapping lesion of major salivary glands	0.511	0.489	0.000
C08.1 Sublingual gland	0.511	0.489	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.510	0.489	0.000
D69.4 Other primary thrombocytopenia	0.510	0.490	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.510	0.490	0.000
C05.8 Overlapping lesion of palate	0.509	0.491	0.000
C05.2 Uvula	0.509	0.491	0.000
D68.0 Von Willebrand's disease	0.509	0.491	0.000
Q04 Other congenital malformations of brain	0.508	0.492	0.000
L41.9 Parapsoriasis, unspecified	0.507	0.493	0.000
L41.8 Other parapsoriasis	0.507	0.493	0.000
L41.5 Retiform parapsoriasis	0.507	0.493	0.000
L41.4 Large plaque parapsoriasis	0.507	0.493	0.000
L41.3 Small plaque parapsoriasis	0.507	0.493	0.000
L41.2 Lymphomatoid papulosis	0.507	0.493	0.000
L41.1 Pityriasis lichenoides chronica	0.507	0.493	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.507	0.493	0.000
K51.4 Pseudopolyposis of colon	0.506	0.494	0.000
D84 Other immunodeficiencies	0.505	0.494	0.000
C03.9 Gum, unspecified	0.505	0.495	0.000
C03.0 Upper gum	0.505	0.495	0.000
C81.0 Lymphocytic predominance	0.504	0.495	0.000
Q06 Other congenital malformations of spinal cord	0.503	0.497	0.000
Q01 Encephalocele	0.503	0.497	0.000
Q00 Anencephaly and similar malformations	0.503	0.497	0.000
Q02 Microcephaly	0.503	0.497	0.000
Q34 Other congenital malformations of respiratory system	0.503	0.497	0.000
Q33 Congenital malformations of lung	0.503	0.497	0.000
Q32 Congenital malformations of trachea and bronchus	0.503	0.497	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.502	0.498	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.502	0.498	0.000
G37 Other demyelinating diseases of central nervous system	0.004	0.498	0.497
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.498	0.502	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations