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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3135395
log Bayes Factor = 306.183
Chromosome 6   position 32,405,192  (GRCh37) Explore rs3135395 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.001 0.999
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
E10.5 With peripheral circulatory complications
0.000 0.002 0.998
M06.0 Seronegative rheumatoid arthritis
0.000 0.003 0.997
E10.2 With renal complications
0.000 0.003 0.997
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.003 0.997
J32 Chronic sinusitis
0.000 0.008 0.992
J33.8 Other polyp of sinus
0.000 0.010 0.990
E06 Thyroiditis
0.000 0.010 0.990
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.012 0.988
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.012 0.988
M34 Systemic sclerosis
0.000 0.013 0.987
E11.1 With ketoacidosis
0.000 0.014 0.986
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.015 0.985
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.015 0.985
M06.3 Rheumatoid nodule
0.000 0.016 0.984
E11.3 With ophthalmic complications
0.000 0.017 0.983
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.017 0.983
E06.3 Autoimmune thyroiditis
0.000 0.020 0.980
E11.9 Without complications
0.000 0.024 0.976
K90 Intestinal malabsorption
0.000 0.027 0.973
E10.0 With coma
0.000 0.031 0.969
E07 Other disorders of thyroid
0.000 0.032 0.968
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.033 0.967
Chapter XI Diseases of the digestive system
0.000 0.036 0.964
K90-K93 Other diseases of the digestive system
0.000 0.037 0.963
G35-G37 Demyelinating diseases of the central nervous system
0.957 0.038 0.005
H36 Retinal disorders in diseases classified elsewhere
0.000 0.042 0.958
K70-K77 Diseases of liver
0.000 0.043 0.957
K75 Other inflammatory liver diseases
0.000 0.044 0.956
K75.4 Autoimmune hepatitis
0.000 0.045 0.955
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.046 0.954
M06.4 Inflammatory polyarthropathy
0.000 0.046 0.954
E11.4 With neurological complications
0.000 0.046 0.954
E10.8 With unspecified complications
0.000 0.047 0.953
E11.5 With peripheral circulatory complications
0.000 0.047 0.953
G37 Other demyelinating diseases of central nervous system
0.947 0.051 0.002
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.052 0.948
L43 Lichen planus
0.000 0.053 0.947
L43.9 Lichen planus, unspecified
0.000 0.055 0.945
L40-L45 Papulosquamous disorders
0.000 0.056 0.944
M45-M49 Spondylopathies
0.000 0.057 0.943
M45 Ankylosing spondylitis
0.000 0.057 0.943
G37.9 Demyelinating disease of central nervous system, unspecified
0.942 0.058 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.059 0.941
M34.1 CR(E)ST syndrome
0.000 0.060 0.940
J47 Bronchiectasis
0.000 0.061 0.939
J32.0 Chronic maxillary sinusitis
0.000 0.061 0.939
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.064 0.936
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.064 0.936
E07.9 Disorder of thyroid, unspecified
0.000 0.071 0.929
H30-H36 Disorders of choroid and retina
0.000 0.073 0.927
Chapter VII Diseases of the eye and adnexa
0.000 0.077 0.923
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.078 0.922
M34.9 Systemic sclerosis, unspecified
0.000 0.078 0.922
J32.4 Chronic pansinusitis
0.000 0.078 0.922
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.082 0.918
M35.1 Other overlap syndromes
0.000 0.086 0.914
K73 Chronic hepatitis, not elsewhere classified
0.000 0.105 0.895
J46 Status asthmaticus
0.000 0.108 0.892
E14.1 With ketoacidosis
0.000 0.109 0.891
L43.8 Other lichen planus
0.000 0.111 0.889
J20-J22 Other acute lower respiratory infections
0.000 0.112 0.888
M30 Polyarteritis nodosa and related conditions
0.000 0.116 0.884
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.117 0.883
J32.9 Chronic sinusitis, unspecified
0.000 0.118 0.882
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.123 0.877
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.124 0.876
D64.9 Anaemia, unspecified
0.000 0.124 0.876
E10.6 With other specified complications
0.000 0.125 0.875
D60-D64 Aplastic and other anaemias
0.000 0.128 0.872
D64 Other anaemias
0.000 0.129 0.871
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.129 0.871
E14.6 With other specified complications
0.000 0.130 0.870
K82 Other diseases of gallbladder
0.000 0.133 0.867
M65-M68 Disorders of synovium and tendon
0.000 0.137 0.863
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.138 0.862
K82.8 Other specified diseases of gallbladder
0.000 0.139 0.861
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.141 0.859
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.153 0.847
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.160 0.840
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.162 0.838
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.165 0.835
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.168 0.832
E11.2 With renal complications
0.000 0.170 0.830
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.170 0.830
J22 Unspecified acute lower respiratory infection
0.000 0.172 0.828
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.175 0.825
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.178 0.822
M35.0 Sicca syndrome [Sjogren]
0.000 0.179 0.821
J32.8 Other chronic sinusitis
0.000 0.180 0.820
E11.8 With unspecified complications
0.000 0.186 0.814
M65 Synovitis and tenosynovitis
0.000 0.190 0.810
J84 Other interstitial pulmonary diseases
0.000 0.192 0.808
E07.8 Other specified disorders of thyroid
0.000 0.193 0.807
M35.7 Hypermobility syndrome
0.000 0.196 0.804
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.198 0.802
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.198 0.802
M14 Arthropathies in other diseases classified elsewhere
0.000 0.201 0.799
M35.2 Behcet's disease
0.000 0.201 0.799
E14.8 With unspecified complications
0.000 0.201 0.799
E11.6 With other specified complications
0.000 0.216 0.784
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.218 0.782
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.218 0.782
K90.9 Intestinal malabsorption, unspecified
0.000 0.218 0.782
E03.8 Other specified hypothyroidism
0.000 0.218 0.782
K81 Cholecystitis
0.000 0.220 0.780
E14.2 Withrenal complications
0.000 0.221 0.779
L80 Vitiligo
0.000 0.221 0.779
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.223 0.777
K73.9 Chronic hepatitis, unspecified
0.000 0.226 0.773
K82.2 Perforation of gallbladder
0.000 0.227 0.773
J60-J70 Lung diseases due to external agents
0.000 0.228 0.772
L10-L14 Bullous disorders
0.000 0.228 0.772
E06.9 Thyroiditis, unspecified
0.000 0.231 0.769
J32.2 Chronic ethmoidal sinusitis
0.000 0.236 0.764
K81.9 Cholecystitis, unspecified
0.000 0.236 0.764
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.241 0.759
M30.0 Polyarteritis nodosa
0.000 0.245 0.755
K75.9 Inflammatory liver disease, unspecified
0.000 0.247 0.753
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.248 0.752
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.248 0.752
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.249 0.751
H34 Retinal vascular occlusions
0.000 0.254 0.746
M34.8 Other forms of systemic sclerosis
0.000 0.254 0.746
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.256 0.744
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.258 0.742
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.260 0.740
E14.4 With neurological complications
0.000 0.261 0.739
M60-M63 Disorders of muscles
0.000 0.264 0.736
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.264 0.736
E14.5 With peripheral circulatory complications
0.000 0.272 0.728
J37 Chronic laryngitis and laryngotracheitis
0.000 0.273 0.727
K82.3 Fistula of gallbladder
0.000 0.273 0.727
Chapter VIII Diseases of the ear and mastoid process
0.000 0.274 0.726
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.277 0.723
K75.8 Other specified inflammatory liver diseases
0.000 0.277 0.723
J86 Pyothorax
0.000 0.278 0.722
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M80-M85 Disorders of bone density and structure
0.000 0.284 0.716
K74 Fibrosis and cirrhosis of liver
0.000 0.284 0.716
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.285 0.715
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.285 0.715
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.285 0.715
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.285 0.715
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.285 0.715
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.285 0.715
M49 Spondylopathies in diseases classified elsewhere
0.000 0.290 0.710
K72 Hepatic failure, not elsewhere classified
0.000 0.290 0.710
E06.5 Other chronic thyroiditis
0.000 0.290 0.709
E06.4 Drug-induced thyroiditis
0.000 0.290 0.709
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.290 0.709
E06.1 Subacute thyroiditis
0.000 0.290 0.709
E06.0 Acute thyroiditis
0.000 0.290 0.709
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.293 0.707
M34.0 Progressive systemic sclerosis
0.000 0.293 0.707
E16.1 Other hypoglycaemia
0.000 0.293 0.707
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.295 0.705
M06.38 Rheumatoid nodule (Other)
0.000 0.295 0.705
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.295 0.705
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.295 0.705
M06.33 Rheumatoid nodule (Forearm)
0.000 0.295 0.705
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.295 0.705
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.297 0.703
K71 Toxic liver disease
0.000 0.298 0.702
H60-H62 Diseases of external ear
0.000 0.298 0.702
K90.3 Pancreatic steatorrhoea
0.000 0.302 0.698
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.302 0.698
K90.1 Tropical sprue
0.000 0.302 0.698
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.303 0.697
E07.1 Dyshormogenetic goitre
0.000 0.306 0.694
E07.0 Hypersecretion of calcitonin
0.000 0.306 0.694
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.306 0.694
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.308 0.692
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.310 0.690
M14.6 Neuropathic arthropathy
0.000 0.310 0.690
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.311 0.689
M32 Systemic lupus erythematosus
0.000 0.313 0.687
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.313 0.687
K77 Liver disorders in diseases classified elsewhere
0.000 0.314 0.686
K75.2 Nonspecific reactive hepatitis
0.000 0.315 0.685
K75.1 Phlebitis of portal vein
0.000 0.315 0.685
M15-M19 Arthrosis
0.000 0.315 0.685
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.316 0.684
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.316 0.684
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.316 0.684
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.316 0.684
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.316 0.684
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.316 0.684
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.316 0.684
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.316 0.684
M80 Osteoporosis with pathological fracture
0.000 0.316 0.684
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.316 0.684
G37.8 Other specified demyelinating diseases of central nervous system
0.682 0.317 0.001
M12 Other specific arthropathies
0.000 0.318 0.682
M18 Arthrosis of first carpometacarpal joint
0.000 0.318 0.682
G37.5 Concentric sclerosis [Balo]
0.679 0.320 0.001
G37.4 Subacute necrotising myelitis
0.679 0.320 0.001
G37.2 Central pontine myelinolysis
0.679 0.320 0.001
G37.1 Central demyelination of corpus callosum
0.679 0.320 0.001
G37.0 Diffuse sclerosis
0.679 0.320 0.001
J85 Abscess of lung and mediastinum
0.000 0.321 0.679
L43.3 Subacute (active) lichen planus
0.000 0.321 0.679
L43.2 Lichenoid drug reaction
0.000 0.321 0.679
L43.1 Bullous lichen planus
0.000 0.321 0.679
L43.0 Hypertrophic lichen planus
0.000 0.321 0.679
L41 Parapsoriasis
0.000 0.323 0.677
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.323 0.677
D62 Acute posthaemorrhagic anaemia
0.000 0.323 0.677
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.323 0.677
M24 Other specific joint derangements
0.000 0.324 0.676
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.324 0.676
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.324 0.676
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.324 0.676
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.324 0.676
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.324 0.676
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.324 0.676
L94 Other localised connective tissue disorders
0.000 0.325 0.675
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.325 0.675
H40-H42 Glaucoma
0.000 0.327 0.673
E05.8 Other thyrotoxicosis
0.000 0.329 0.671
M91-M94 Chondropathies
0.000 0.330 0.670
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.330 0.670
E83 Disorders of mineral metabolism
0.655 0.330 0.015
J45.1 Nonallergic asthma
0.000 0.331 0.669
H30 Chorioretinal inflammation
0.000 0.333 0.666
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.333 0.666
M31 Other necrotising vasculopathies
0.000 0.334 0.666
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.335 0.665
J41 Simple and mucopurulent chronic bronchitis
0.000 0.336 0.664
E40-E46 Malnutrition
0.000 0.336 0.664
L12 Pemphigoid
0.000 0.338 0.662
H61 Other disorders of external ear
0.000 0.338 0.662
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.340 0.660
K85 Acute pancreatitis
0.000 0.341 0.659
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.344 0.656
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.344 0.656
J32.1 Chronic frontal sinusitis
0.000 0.345 0.655
G36 Other acute disseminated demyelination
0.650 0.346 0.004
M20 Acquired deformities of fingers and toes
0.000 0.347 0.653
D50-D53 Nutritional anaemias
0.000 0.348 0.652
M65.1 Other infective (teno)synovitis
0.000 0.349 0.651
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.349 0.651
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.350 0.650
M60 Myositis
0.000 0.350 0.650
J31.2 Chronic pharyngitis
0.000 0.351 0.649
H43-H45 Disorders of vitreous body and globe
0.000 0.352 0.648
M86-M90 Other osteopathies
0.000 0.353 0.647
E13 Other specified diabetes mellitus
0.000 0.354 0.646
J21 Acute bronchiolitis
0.000 0.355 0.644
M82 Osteoporosis in diseases classified elsewhere
0.000 0.357 0.643
L44 Other papulosquamous disorders
0.000 0.357 0.643
M07 Psoriatic and enteropathic arthropathies
0.000 0.357 0.643
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.358 0.642
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.358 0.642
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.358 0.642
H10-H13 Disorders of conjunctiva
0.000 0.360 0.640
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.363 0.637
E11.0 With coma
0.000 0.364 0.636
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.366 0.634
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.366 0.634
M30.2 Juvenile polyarteritis
0.000 0.366 0.634
J42 Unspecified chronic bronchitis
0.000 0.366 0.634
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.368 0.632
J45.8 Mixed asthma
0.000 0.370 0.629
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.372 0.628
L95.8 Other vasculitis limited to skin
0.000 0.373 0.627
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.375 0.625
D64.4 Congenital dyserythropoietic anaemia
0.000 0.375 0.625
D64.3 Other sideroblastic anaemias
0.000 0.375 0.625
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.375 0.625
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.375 0.625
D64.0 Hereditary sideroblastic anaemia
0.000 0.375 0.625
L83 Acanthosis nigricans
0.000 0.378 0.622
K82.9 Disease of gallbladder, unspecified
0.000 0.380 0.620
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.381 0.619
K74.3 Primary biliary cirrhosis
0.000 0.382 0.618
K74.5 Biliary cirrhosis, unspecified
0.000 0.383 0.617
M00-M03 Infectious arthropathies
0.000 0.384 0.616
H60 Otitis externa
0.000 0.384 0.616
K90.8 Other intestinal malabsorption
0.000 0.384 0.615
L84 Corns and callosities
0.000 0.389 0.611
H61.8 Other specified disorders of external ear
0.000 0.389 0.611
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.390 0.610
L57.0 Actinic keratosis
0.000 0.390 0.610
H34.2 Other retinal artery occlusions
0.000 0.391 0.609
E83.5 Disorders of calcium metabolism
0.607 0.392 0.000
M86 Osteomyelitis
0.000 0.395 0.605
J31.1 Chronic nasopharyngitis
0.000 0.395 0.605
M10 Gout
0.000 0.396 0.604
K75.0 Abscess of liver
0.000 0.397 0.603
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.398 0.602
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.399 0.601
L87 Transepidermal elimination disorders
0.000 0.399 0.601
L86 Keratoderma in diseases classified elsewhere
0.000 0.399 0.601
E03.1 Congenital hypothyroidism without goitre
0.000 0.400 0.600
K50-K52 Noninfective enteritis and colitis
0.009 0.402 0.589
D50 Iron deficiency anaemia
0.000 0.403 0.597
L13 Other bullous disorders
0.000 0.404 0.595
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.594 0.405 0.001
K85.1 Biliary acute pancreatitis
0.000 0.406 0.594
J69 Pneumonitis due to solids and liquids
0.000 0.407 0.593
J86.0 Pyothorax with fistula
0.000 0.409 0.591
M82.1 Osteoporosis in endocrine disorders
0.000 0.409 0.591
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.409 0.591
L42 Pityriasis rosea
0.000 0.410 0.590
M66 Spontaneous rupture of synovium and tendon
0.000 0.411 0.589
K72.0 Acute and subacute hepatic failure
0.000 0.415 0.585
M35.8 Other specified systemic involvement of connective tissue
0.000 0.417 0.583
M11 Other crystal arthropathies
0.000 0.419 0.580
M65.2 Calcific tendinitis
0.000 0.419 0.580
M65.0 Abscess of tendon sheath
0.000 0.419 0.580
L12.1 Cicatricial pemphigoid
0.000 0.420 0.580
J85.2 Abscess of lung without pneumonia
0.000 0.421 0.579
M86.9 Osteomyelitis, unspecified
0.000 0.422 0.578
J67.2 Bird fancier's lung
0.000 0.424 0.576
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.426 0.574
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.427 0.573
M14.4 Arthropathy in amyloidosis
0.000 0.427 0.573
M14.3 Lipoid dermatoarthritis
0.000 0.427 0.573
M14.2 Diabetic arthropathy
0.000 0.427 0.573
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.427 0.573
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.427 0.573
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.427 0.573
J43 Emphysema
0.000 0.428 0.572
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.430 0.569
J86.9 Pyothorax without fistula
0.000 0.431 0.569
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.432 0.568
D50.9 Iron deficiency anaemia, unspecified
0.000 0.434 0.566
M24.1 Other articular cartilage disorders
0.000 0.434 0.566
H34.1 Central retinal artery occlusion
0.000 0.435 0.565
M24.7 Protrusio acetabuli
0.000 0.436 0.564
M60.0 Infective myositis
0.000 0.438 0.562
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.438 0.562
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.439 0.560
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.441 0.559
K81.1 Chronic cholecystitis
0.000 0.441 0.559
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.441 0.559
J45.0 Predominantly allergic asthma
0.000 0.442 0.558
K52 Other non-infective gastro-enteritis and colitis
0.003 0.442 0.555
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.443 0.557
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.443 0.557
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.443 0.557
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.443 0.557
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.443 0.557
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.443 0.557
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.443 0.557
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.443 0.557
H31 Other disorders of choroid
0.001 0.444 0.556
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.446 0.554
J66 Airway disease due to specific organic dust
0.000 0.446 0.554
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.446 0.554
J62 Pneumoconiosis due to dust containing silica
0.000 0.446 0.554
J65 Pneumoconiosis associated with tuberculosis
0.000 0.446 0.554
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.446 0.554
L94.2 Calcinosis cutis
0.000 0.446 0.554
E83.9 Disorder of mineral metabolism, unspecified
0.545 0.446 0.009
L10 Pemphigus
0.000 0.446 0.553
L14 Bullous disorders in diseases classified elsewhere
0.000 0.446 0.553
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.447 0.553
J60 Coalworker's pneumoconiosis
0.000 0.447 0.553
H16 Keratitis
0.000 0.449 0.551
H43 Disorders of vitreous body
0.000 0.449 0.551
J84.0 Alveolar and parietoalveolar conditions
0.000 0.450 0.550
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.452 0.548
H34.9 Retinal vascular occlusion, unspecified
0.000 0.452 0.548
K82.1 Hydrops of gallbladder
0.000 0.456 0.544
J95-J99 Other diseases of the respiratory system
0.000 0.457 0.543
H20 Iridocyclitis
0.000 0.457 0.543
H60.3 Other infective otitis externa
0.000 0.457 0.543
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.458 0.542
H61.2 Impacted cerumen
0.000 0.458 0.542
J20 Acute bronchitis
0.000 0.461 0.539
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.461 0.539
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.462 0.538
H11 Other disorders of conjunctiva
0.000 0.465 0.535
E50-E64 Other nutritional deficiencies
0.000 0.465 0.535
H34.0 Transient retinal artery occlusion
0.000 0.465 0.535
K52.1 Toxic gastro-enteritis and colitis
0.000 0.466 0.533
J37.0 Chronic laryngitis
0.000 0.468 0.532
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.470 0.530
M36.3 Arthropathy in other blood disorders
0.000 0.470 0.530
M36.2 Haemophilic arthropathy
0.000 0.470 0.530
M36.1 Arthropathy in neoplastic disease
0.000 0.470 0.530
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.470 0.530
M20.0 Deformity of finger(s)
0.000 0.471 0.529
D50.8 Other iron deficiency anaemias
0.000 0.471 0.529
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.472 0.528
M61 Calcification and ossification of muscle
0.000 0.472 0.528
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.000 0.472 0.528
L55 Sunburn
0.000 0.472 0.527
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.475 0.525
K82.0 Obstruction of gallbladder
0.000 0.477 0.523
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.000 0.477 0.523
M60.9 Myositis, unspecified
0.000 0.477 0.522
J37.1 Chronic laryngotracheitis
0.000 0.478 0.521
M33 Dermatopolymyositis
0.000 0.480 0.520
H33 Retinal detachments and breaks
0.000 0.480 0.520
L94.0 Localised scleroderma [morphea]
0.000 0.480 0.520
L85 Other epidermal thickening
0.000 0.481 0.519
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.482 0.518
H11.4 Other conjunctival vascular disorders and cysts
0.000 0.482 0.518
M31.1 Thrombotic microangiopathy
0.000 0.485 0.515
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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