TreeWAS – Variant ID: rs3135758

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z85.3 Personal history of malignant neoplasm of breast	0.923	0.077	0.000
C50.9 Breast, unspecified	0.770	0.230	0.000
C50 Malignant neoplasm of breast	0.463	0.537	0.000
C50.1 Central portion of breast	0.404	0.596	0.000
C50.0 Nipple and areola	0.381	0.619	0.000
C50.3 Lower-inner quadrant of breast	0.369	0.630	0.000
C50.4 Upper-outer quadrant of breast	0.334	0.666	0.000
C50.6 Axillary tail of breast	0.332	0.668	0.000
C50.5 Lower-outer quadrant of breast	0.294	0.706	0.000
C50.2 Upper-inner quadrant of breast	0.270	0.730	0.000
C50-C50 Malignant neoplasm of breast	0.221	0.779	0.000
C50.8 Overlapping lesion of breast	0.149	0.851	0.001
D27 Benign neoplasm of ovary	0.000	0.893	0.107
M25 Other joint disorders, not elsewhere classified	0.061	0.939	0.000
M25.4 Effusion of joint	0.059	0.941	0.000
M24 Other specific joint derangements	0.059	0.941	0.000
M06.9 Rheumatoid arthritis, unspecified	0.059	0.941	0.000
M06 Other rheumatoid arthritis	0.058	0.942	0.000
M79.8 Other specified soft tissue disorders	0.057	0.943	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.057	0.943	0.000
M05-M14 Inflammatory polyarthropathies	0.057	0.943	0.000
M20-M25 Other joint disorders	0.057	0.943	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.057	0.943	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.056	0.944	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.056	0.944	0.000
D46 Myelodysplastic syndromes	0.056	0.944	0.000
M24.1 Other articular cartilage disorders	0.055	0.945	0.000
M25.46 Effusion of joint (Lower leg)	0.055	0.945	0.000
D48.5 Skin	0.055	0.945	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.054	0.945	0.000
M70-M79 Other soft tissue disorders	0.054	0.946	0.000
M25.0 Haemarthrosis	0.053	0.947	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.053	0.947	0.000
M24.0 Loose body in joint	0.053	0.947	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.052	0.948	0.000
M10 Gout	0.052	0.948	0.000
M25.3 Other instability of joint	0.052	0.948	0.000
M79.6 Pain in limb	0.052	0.948	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.051	0.949	0.000
M25.47 Effusion of joint (Ankle and foot)	0.051	0.949	0.000
M25.5 Pain in joint	0.050	0.950	0.000
M06.0 Seronegative rheumatoid arthritis	0.050	0.950	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.050	0.950	0.000
M86-M90 Other osteopathies	0.049	0.950	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.049	0.951	0.000
M80-M85 Disorders of bone density and structure	0.049	0.951	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.049	0.951	0.000
D45 Polycythaemia vera	0.048	0.952	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.048	0.952	0.000
M25.06 Haemarthrosis (Lower leg)	0.048	0.952	0.000
Chapter II Neoplasms	0.048	0.952	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.047	0.953	0.000
M10.9 Gout, unspecified	0.047	0.953	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.047	0.953	0.000
M79.67 Pain in limb (Ankle and foot)	0.047	0.953	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.047	0.953	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.047	0.953	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.047	0.953	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.047	0.953	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.046	0.954	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.046	0.954	0.000
M25.9 Joint disorder, unspecified	0.046	0.954	0.000
M24.2 Disorder of ligament	0.046	0.954	0.000
M25.56 Pain in joint (Lower leg)	0.046	0.954	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.046	0.954	0.000
M45-M49 Spondylopathies	0.046	0.954	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.046	0.954	0.000
M25.8 Other specified joint disorders	0.046	0.954	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.046	0.954	0.000
M25.53 Pain in joint (Forearm)	0.046	0.954	0.000
M25.43 Effusion of joint (Forearm)	0.045	0.954	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.045	0.954	0.000
D46.2 Refractory anaemia with excess of blasts	0.045	0.954	0.000
M06.3 Rheumatoid nodule	0.045	0.955	0.000
M79.88 Other specified soft tissue disorders (Other)	0.045	0.955	0.000
M79.66 Pain in limb (Lower leg)	0.045	0.955	0.000
M21 Other acquired deformities of limbs	0.045	0.955	0.000
M33 Dermatopolymyositis	0.045	0.955	0.000
M24.07 Loose body in joint (Ankle and foot)	0.044	0.956	0.000
M77 Other enthesopathies	0.044	0.956	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.044	0.956	0.000
M25.2 Flail joint	0.044	0.956	0.000
M25.1 Fistula of joint	0.044	0.956	0.000
M07 Psoriatic and enteropathic arthropathies	0.044	0.956	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.044	0.956	0.000
M86 Osteomyelitis	0.043	0.957	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.043	0.957	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.043	0.957	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.043	0.957	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.043	0.957	0.000
M25.49 Effusion of joint (Site unspecified)	0.043	0.957	0.000
M25.48 Effusion of joint (Other)	0.043	0.957	0.000
M25.44 Effusion of joint (Hand)	0.043	0.957	0.000
M25.42 Effusion of joint (Upper arm)	0.043	0.957	0.000
M25.41 Effusion of joint (Shoulder region)	0.043	0.957	0.000
M25.40 Effusion of joint (Multiple sites)	0.043	0.957	0.000
M79.2 Neuralgia and neuritis, unspecified	0.043	0.957	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.043	0.957	0.000
C18.2 Ascending colon	0.043	0.957	0.000
M79.69 Pain in limb (Site unspecified)	0.043	0.957	0.000
M24.02 Loose body in joint (Upper arm)	0.043	0.957	0.000
M79.60 Pain in limb (Multiple sites)	0.043	0.957	0.000
M24.9 Joint derangement, unspecified	0.042	0.957	0.000
M24.7 Protrusio acetabuli	0.042	0.957	0.000
M24.6 Ankylosis of joint	0.042	0.957	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.042	0.957	0.000
C51-C58 Malignant neoplasms of female genital organs	0.042	0.958	0.000
M24.01 Loose body in joint (Shoulder region)	0.042	0.958	0.000
C15-C26 Malignant neoplasms of digestive organs	0.042	0.958	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.042	0.958	0.000
M24.5 Contracture of joint	0.042	0.958	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.042	0.958	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.042	0.958	0.000
M06.8 Other specified rheumatoid arthritis	0.042	0.958	0.000
M06.2 Rheumatoid bursitis	0.042	0.958	0.000
M06.1 Adult-onset Still's disease	0.042	0.958	0.000
M32 Systemic lupus erythematosus	0.042	0.958	0.000
M60-M63 Disorders of muscles	0.042	0.958	0.000
C18 Malignant neoplasm of colon	0.042	0.958	0.000
M14 Arthropathies in other diseases classified elsewhere	0.042	0.958	0.000
M25.31 Other instability of joint (Shoulder region)	0.042	0.958	0.000
M79.61 Pain in limb (Shoulder region)	0.042	0.958	0.000
M46 Other inflammatory spondylopathies	0.042	0.958	0.000
M00-M03 Infectious arthropathies	0.041	0.958	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.041	0.959	0.000
M79.5 Residual foreign body in soft tissue	0.041	0.959	0.000
C18.0 Caecum	0.041	0.959	0.000
M12 Other specific arthropathies	0.041	0.959	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.041	0.959	0.000
M08 Juvenile arthritis	0.041	0.959	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.041	0.959	0.000
M30 Polyarteritis nodosa and related conditions	0.041	0.959	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.041	0.959	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.041	0.959	0.000
M34 Systemic sclerosis	0.041	0.959	0.000
M25.37 Other instability of joint (Ankle and foot)	0.041	0.959	0.000
M71 Other bursopathies	0.041	0.959	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.041	0.959	0.000
M87 Osteonecrosis	0.041	0.959	0.000
M79.9 Soft tissue disorder, unspecified	0.040	0.960	0.000
M79.3 Panniculitis, unspecified	0.040	0.960	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.040	0.960	0.000
D46.7 Other myelodysplastic syndromes	0.040	0.960	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.040	0.960	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.040	0.960	0.000
D46.4 Refractory anaemia, unspecified	0.040	0.960	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.040	0.960	0.000
D46.1 Refractory anaemia with sideroblasts	0.040	0.960	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.040	0.960	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.040	0.960	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.040	0.960	0.000
M24.18 Other articular cartilage disorders (Other)	0.040	0.960	0.000
M24.14 Other articular cartilage disorders (Hand)	0.040	0.960	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.040	0.960	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.040	0.960	0.000
M76 Enthesopathies of lower limb, excluding foot	0.039	0.961	0.000
C15 Malignant neoplasm of oesophagus	0.039	0.961	0.000
M89 Other disorders of bone	0.039	0.961	0.000
M11 Other crystal arthropathies	0.039	0.961	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.039	0.961	0.000
M25.54 Pain in joint (Hand)	0.039	0.961	0.000
D37.7 Other digestive organs	0.039	0.961	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.039	0.961	0.000
M10.0 Idiopathic gout	0.039	0.961	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.039	0.961	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.039	0.961	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.039	0.961	0.000
M84 Disorders of continuity of bone	0.039	0.961	0.000
M25.36 Other instability of joint (Lower leg)	0.039	0.961	0.000
M21.0 Valgus deformity, not elsewhere classified	0.039	0.961	0.000
M25.09 Haemarthrosis (Site unspecified)	0.038	0.962	0.000
M25.08 Haemarthrosis (Other)	0.038	0.962	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.038	0.962	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.038	0.962	0.000
M25.04 Haemarthrosis (Hand)	0.038	0.962	0.000
M25.03 Haemarthrosis (Forearm)	0.038	0.962	0.000
M25.02 Haemarthrosis (Upper arm)	0.038	0.962	0.000
M25.01 Haemarthrosis (Shoulder region)	0.038	0.962	0.000
M25.00 Haemarthrosis (Multiple sites)	0.038	0.962	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.038	0.962	0.000
D48.4 Peritoneum	0.038	0.962	0.000
D48.3 Retroperitoneum	0.038	0.962	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.038	0.962	0.000
C16 Malignant neoplasm of stomach	0.038	0.962	0.000
M24.09 Loose body in joint (Site unspecified)	0.038	0.962	0.000
M24.08 Loose body in joint (Other)	0.038	0.962	0.000
M24.06 Loose body in joint-Lower leg	0.038	0.962	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.038	0.962	0.000
M24.04 Loose body in joint (Hand)	0.038	0.962	0.000
M24.03 Loose body in joint (Forearm)	0.038	0.962	0.000
M24.00 Loose body in joint (Multiple sites)	0.038	0.962	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.038	0.962	0.000
M85 Other disorders of bone density and structure	0.038	0.962	0.000
M06.4 Inflammatory polyarthropathy	0.038	0.962	0.000
M25.7 Osteophyte	0.038	0.962	0.000
M40-M43 Deforming dorsopathies	0.038	0.962	0.000
D44.8 Pluriglandular involvement	0.038	0.962	0.000
D48.0 Bone and articular cartilage	0.037	0.962	0.000
M91-M94 Chondropathies	0.038	0.962	0.000
M81 Osteoporosis without pathological fracture	0.037	0.963	0.000
M10.4 Other secondary gout	0.037	0.963	0.000
M10.3 Gout due to impairment of renal function	0.037	0.963	0.000
M10.2 Drug-induced gout	0.037	0.963	0.000
M10.1 Lead-induced gout	0.037	0.963	0.000
M25.39 Other instability of joint (Site unspecified)	0.037	0.963	0.000
M25.38 Other instability of joint (Other)	0.037	0.963	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.037	0.963	0.000
M25.34 Other instability of joint (Hand)	0.037	0.963	0.000
M25.33 Other instability of joint (Forearm)	0.037	0.963	0.000
M25.32 Other instability of joint (Upper arm)	0.037	0.963	0.000
M25.30 Other instability of joint (Multiple sites)	0.037	0.963	0.000
M79.68 Pain in limb (Other)	0.037	0.963	0.000
M77.4 Metatarsalgia	0.037	0.963	0.000
C54 Malignant neoplasm of corpus uteri	0.037	0.963	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.037	0.963	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.037	0.963	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.037	0.963	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.037	0.963	0.000
M80 Osteoporosis with pathological fracture	0.037	0.963	0.000
M24.26 Disorder of ligament (Lower leg)	0.037	0.963	0.000
M86.9 Osteomyelitis, unspecified	0.037	0.963	0.000
M10.99 Gout, unspecified (Site unspecified)	0.037	0.963	0.000
M05 Seropositive rheumatoid arthritis	0.037	0.963	0.000
M24.24 Disorder of ligament (Hand)	0.036	0.964	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.036	0.964	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.036	0.964	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.036	0.964	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.036	0.964	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.036	0.964	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.036	0.964	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.036	0.964	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.036	0.964	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.036	0.964	0.000
D37.9 Digestive organ, unspecified	0.036	0.964	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.036	0.964	0.000
M25.84 Other specified joint disorders (Hand)	0.036	0.964	0.000
M24.23 Disorder of ligament (Forearm)	0.036	0.964	0.000
M06.34 Rheumatoid nodule (Hand)	0.036	0.964	0.000
C53 Malignant neoplasm of cervix uteri	0.036	0.964	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.036	0.964	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.036	0.964	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.036	0.964	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.036	0.964	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.036	0.964	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.036	0.964	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.036	0.964	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.036	0.964	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.036	0.964	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.036	0.964	0.000
M79.1 Myalgia	0.036	0.964	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.036	0.964	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.035	0.964	0.000
C15.5 Lower third of oesophagus	0.036	0.964	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.035	0.964	0.000
M47 Spondylosis	0.036	0.964	0.000
M65-M68 Disorders of synovium and tendon	0.035	0.964	0.000
D37.4 Colon	0.035	0.965	0.000
M25.58 Pain in joint (Other)	0.035	0.965	0.000
D37.2 Small intestine	0.035	0.965	0.000
D48.6 Breast	0.035	0.965	0.000
D40.0 Prostate	0.035	0.965	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.035	0.965	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.035	0.965	0.000
M25.88 Other specified joint disorders (Other)	0.035	0.965	0.000
M33.1 Other dermatomyositis	0.035	0.965	0.000
M83 Adult osteomalacia	0.035	0.965	0.000
M82 Osteoporosis in diseases classified elsewhere	0.035	0.965	0.000
M25.83 Other specified joint disorders (Forearm)	0.035	0.965	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.035	0.965	0.000
M86.8 Other osteomyelitis	0.035	0.965	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.035	0.965	0.000
M77.5 Other enthesopathy of foot	0.034	0.965	0.000
M07.3 Other psoriatic arthropathies	0.034	0.965	0.000
C15.9 Oesophagus, unspecified	0.034	0.965	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.034	0.966	0.000
M77.9 Enthesopathy, unspecified	0.034	0.966	0.000
M10.98 Gout, unspecified (Other)	0.034	0.966	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.034	0.966	0.000
M10.93 Gout, unspecified (Forearm)	0.034	0.966	0.000
M10.92 Gout, unspecified (Upper arm)	0.034	0.966	0.000
M10.91 Gout, unspecified (Shoulder region)	0.034	0.966	0.000
M10.90 Gout, unspecified (Multiple sites)	0.034	0.966	0.000
M89.9 Disorder of bone, unspecified	0.034	0.966	0.000
D37.1 Stomach	0.034	0.966	0.000
M31 Other necrotising vasculopathies	0.034	0.966	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.034	0.966	0.000
M21.4 Flat foot [pes planus] (acquired)	0.034	0.966	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.034	0.966	0.000
C23 Malignant neoplasm of gallbladder	0.034	0.966	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.034	0.966	0.000
C18.1 Appendix	0.034	0.966	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.034	0.966	0.000
M99 Biomechanical lesions, not elsewhere classified	0.034	0.966	0.000
D39.1 Ovary	0.034	0.966	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.034	0.966	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.033	0.966	0.000
C54.1 Endometrium	0.034	0.966	0.000
M45 Ankylosing spondylitis	0.033	0.967	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.033	0.967	0.000
M25.98 Joint disorder, unspecified (Other)	0.033	0.967	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.033	0.967	0.000
M25.94 Joint disorder, unspecified (Hand)	0.033	0.967	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.033	0.967	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.033	0.967	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.033	0.967	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.033	0.967	0.000
M24.29 Disorder of ligament (Site unspecified)	0.033	0.967	0.000
M24.28 Disorder of ligament (Other)	0.033	0.967	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.033	0.967	0.000
M24.22 Disorder of ligament (Upper arm)	0.033	0.967	0.000
M24.21 Disorder of ligament (Shoulder region)	0.033	0.967	0.000
M24.20 Disorder of ligament (Multiple sites)	0.033	0.967	0.000
M33.2 Polymyositis	0.033	0.967	0.000
D37.3 Appendix	0.033	0.967	0.000
M10.94 Gout, unspecified (Hand)	0.033	0.967	0.000
M87.2 Osteonecrosis due to previous trauma	0.033	0.967	0.000
M49 Spondylopathies in diseases classified elsewhere	0.033	0.967	0.000
M79.62 Pain in limb (Upper arm)	0.033	0.967	0.000
D37.5 Rectum	0.033	0.967	0.000
M90 Osteopathies in diseases classified elsewhere	0.033	0.967	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.033	0.967	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.033	0.967	0.000
M25.82 Other specified joint disorders (Upper arm)	0.033	0.967	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.033	0.967	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.033	0.967	0.000
M79.7 Fibromyalgia	0.033	0.967	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.033	0.967	0.000
M24.56 Contracture of joint (Lower leg)	0.033	0.967	0.000
D44.9 Endocrine gland, unspecified	0.033	0.967	0.000
D44.7 Aortic body and other paraganglia	0.033	0.967	0.000
D44.6 Carotid body	0.033	0.967	0.000
D44.5 Pineal gland	0.033	0.967	0.000
D44.4 Craniopharyngeal duct	0.033	0.967	0.000
D44.3 Pituitary gland	0.033	0.967	0.000
D44.2 Parathyroid gland	0.033	0.967	0.000
D44.1 Adrenal gland	0.033	0.967	0.000
D44.0 Thyroid gland	0.033	0.967	0.000
M79.0 Rheumatism, unspecified	0.033	0.967	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.033	0.967	0.000
M06.38 Rheumatoid nodule (Other)	0.033	0.967	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.033	0.967	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.033	0.967	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.033	0.967	0.000
M06.33 Rheumatoid nodule (Forearm)	0.033	0.967	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.033	0.967	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.033	0.967	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.033	0.967	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.033	0.967	0.000
D48.7 Other specified sites	0.032	0.967	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.032	0.967	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.033	0.967	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.032	0.968	0.000
M21.9 Acquired deformity of limb, unspecified	0.032	0.968	0.000
M21.8 Other specified acquired deformities of limbs	0.032	0.968	0.000
M21.7 Unequal limb length (acquired)	0.032	0.968	0.000
M21.6 Other acquired deformities of ankle and foot	0.032	0.968	0.000
M46.4 Discitis, unspecified	0.032	0.968	0.000
M79.63 Pain in limb (Forearm)	0.032	0.968	0.000
C18.4 Transverse colon	0.032	0.968	0.000
M33.9 Dermatopolymyositis, unspecified	0.032	0.968	0.000
M33.0 Juvenile dermatomyositis	0.032	0.968	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.032	0.968	0.000
M21.2 Flexion deformity	0.032	0.968	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.032	0.968	0.000
M77.3 Calcaneal spur	0.032	0.968	0.000
M77.2 Periarthritis of wrist	0.032	0.968	0.000
M47.1 Other spondylosis with myelopathy	0.032	0.968	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.032	0.968	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.032	0.968	0.000
C56 Malignant neoplasm of ovary	0.032	0.968	0.000
D40.9 Male genital organ, unspecified	0.032	0.968	0.000
D40.7 Other male genital organs	0.032	0.968	0.000
D40.1 Testis	0.032	0.968	0.000
M25.19 Fistula of joint (Site unspecified)	0.032	0.968	0.000
M25.18 Fistula of joint (Other)	0.032	0.968	0.000
M25.17 Fistula of joint (Ankle and foot)	0.032	0.968	0.000
M25.16 Fistula of joint (Lower leg)	0.032	0.968	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.032	0.968	0.000
M25.14 Fistula of joint (Hand)	0.032	0.968	0.000
M25.13 Fistula of joint (Forearm)	0.032	0.968	0.000
M25.12 Fistula of joint (Upper arm)	0.032	0.968	0.000
M25.11 Fistula of joint (Shoulder region)	0.032	0.968	0.000
M25.10 Fistula of joint (Multiple sites)	0.032	0.968	0.000
M25.29 Flail joint (Site unspecified)	0.032	0.968	0.000
M25.28 Flail joint (Other)	0.032	0.968	0.000
M25.27 Flail joint (Ankle and foot)	0.032	0.968	0.000
M25.26 Flail joint (Lower leg)	0.032	0.968	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.032	0.968	0.000
M25.24 Flail joint (Hand)	0.032	0.968	0.000
M25.23 Flail joint (Forearm)	0.032	0.968	0.000
M25.22 Flail joint (Upper arm)	0.032	0.968	0.000
M25.21 Flail joint (Shoulder region)	0.032	0.968	0.000
M25.20 Flail joint (Multiple sites)	0.032	0.968	0.000
C52 Malignant neoplasm of vagina	0.032	0.968	0.000
M07.6 Other enteropathic arthropathies	0.032	0.968	0.000
M07.5 Arthropathy in ulcerative colitis	0.032	0.968	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.032	0.968	0.000
M07.2 Psoriatic spondylitis	0.032	0.968	0.000
M07.1 Arthritis mutilans	0.032	0.968	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.032	0.968	0.000
M62 Other disorders of muscle	0.032	0.968	0.000
D37.6 Liver, gallbladder and bile ducts	0.031	0.968	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.031	0.968	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.031	0.968	0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.031	0.968	0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.031	0.968	0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.031	0.968	0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.031	0.968	0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.031	0.968	0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.031	0.968	0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.031	0.968	0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.031	0.968	0.000
M25.52 Pain in joint (Upper arm)	0.031	0.968	0.000
C45 Mesothelioma	0.031	0.969	0.000
C53.9 Cervix uteri, unspecified	0.031	0.969	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.031	0.969	0.000
M86.6 Other chronic osteomyelitis	0.031	0.969	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.031	0.969	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.031	0.969	0.000
M86.3 Chronic multifocal osteomyelitis	0.031	0.969	0.000
M86.2 Subacute osteomyelitis	0.031	0.969	0.000
M86.1 Other acute osteomyelitis	0.031	0.969	0.000
M86.0 Acute haematogenous osteomyelitis	0.031	0.969	0.000
C16.1 Fundus of stomach	0.031	0.969	0.000
D39.9 Female genital organ, unspecified	0.031	0.969	0.000
D39.7 Other female genital organs	0.031	0.969	0.000
D39.2 Placenta	0.031	0.969	0.000
D39.0 Uterus	0.031	0.969	0.000
M79.64 Pain in limb (Hand)	0.031	0.969	0.000
M81.9 Osteoporosis, unspecified	0.031	0.969	0.000
C16.0 Cardia	0.031	0.969	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.031	0.969	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.031	0.969	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.031	0.969	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.031	0.969	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.031	0.969	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.031	0.969	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.031	0.969	0.000
M34.1 CR(E)ST syndrome	0.031	0.969	0.000
C17 Malignant neoplasm of small intestine	0.031	0.969	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.031	0.969	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.031	0.969	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.031	0.969	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.031	0.969	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.031	0.969	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.031	0.969	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.031	0.969	0.000
M14.6 Neuropathic arthropathy	0.031	0.969	0.000
M85.6 Other cyst of bone	0.031	0.969	0.000
M00 Pyogenic arthritis	0.031	0.969	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.031	0.969	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.031	0.969	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.031	0.969	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.031	0.969	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.031	0.969	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.031	0.969	0.000
M87.9 Osteonecrosis, unspecified	0.031	0.969	0.000
M88 Paget's disease of bone [osteitis deformans]	0.030	0.969	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.031	0.969	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.031	0.969	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.031	0.969	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.031	0.969	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.031	0.969	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.031	0.969	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.031	0.969	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.031	0.969	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.031	0.969	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.031	0.969	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.031	0.969	0.000
M24.68 Ankylosis of joint (Other)	0.031	0.969	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.031	0.969	0.000
M24.66 Ankylosis of joint (Lower leg)	0.031	0.969	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.031	0.969	0.000
M24.64 Ankylosis of joint (Hand)	0.031	0.969	0.000
M24.63 Ankylosis of joint (Forearm)	0.031	0.969	0.000
M24.62 Ankylosis of joint (Upper arm)	0.031	0.969	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.031	0.969	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.031	0.969	0.000
M24.79 Protrusio acetabuli-Site unspec	0.031	0.969	0.000
M24.78 Protrusio acetabuli-Other	0.031	0.969	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.031	0.969	0.000
M24.76 Protrusio acetabuli-Lower leg	0.031	0.969	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.031	0.969	0.000
M24.74 Protrusio acetabuli-Hand	0.031	0.969	0.000
M24.73 Protrusio acetabuli-Forearm	0.031	0.969	0.000
M24.72 Protrusio acetabuli-Upper arm	0.031	0.969	0.000
M24.71 Protrusio acetabuli-Shldr region	0.031	0.969	0.000
M24.70 Protrusio acetabuli-Mult sites	0.031	0.969	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.031	0.969	0.000
M24.98 Joint derangement, unspecified (Other)	0.031	0.969	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.031	0.969	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.031	0.969	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.031	0.969	0.000
M24.94 Joint derangement, unspecified (Hand)	0.031	0.969	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.031	0.969	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.031	0.969	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.031	0.969	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.031	0.969	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.031	0.969	0.000
C58 Malignant neoplasm of placenta	0.031	0.969	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations