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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3173443
log Bayes Factor = 88.6823
Chromosome 6   position 28,137,027  (GRCh37) Explore rs3173443 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.997 0.003 0.000
E05.9 Thyrotoxicosis, unspecified
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.996 0.004 0.000
N40 Hyperplasia of prostate
0.000 0.014 0.986
E10.3 With ophthalmic complications
0.984 0.016 0.000
E14 Unspecified diabetes mellitus
0.980 0.020 0.000
K40 Inguinal hernia
0.000 0.022 0.978
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.025 0.975
E10.1 With ketoacidosis
0.952 0.048 0.000
E20-E35 Disorders of other endocrine glands
0.942 0.058 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.917 0.083 0.000
E14.9 Without complications
0.907 0.093 0.000
E10.2 With renal complications
0.906 0.094 0.000
E27 Other disorders of adrenal gland
0.904 0.096 0.000
E27.1 Primary adrenocortical insufficiency
0.885 0.115 0.000
E11 Non-insulin-dependent diabetes mellitus
0.884 0.116 0.000
E23 Hypofunction and other disorders of pituitary gland
0.880 0.120 0.000
E11.5 With peripheral circulatory complications
0.875 0.125 0.000
E10.6 With other specified complications
0.869 0.131 0.000
E03 Other hypothyroidism
0.861 0.139 0.000
K90 Intestinal malabsorption
0.855 0.144 0.001
E07 Other disorders of thyroid
0.847 0.153 0.000
E14.3 With ophthalmic complications
0.832 0.168 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.825 0.175 0.000
E23.2 Diabetes insipidus
0.822 0.178 0.000
E14.4 With neurological complications
0.808 0.192 0.000
E10.5 With peripheral circulatory complications
0.804 0.196 0.000
E20 Hypoparathyroidism
0.790 0.210 0.000
E03.9 Hypothyroidism, unspecified
0.785 0.215 0.000
E10.0 With coma
0.783 0.217 0.000
E10.7 With multiple complications
0.780 0.220 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.778 0.221 0.000
E14.6 With other specified complications
0.763 0.237 0.000
E11.3 With ophthalmic complications
0.762 0.238 0.000
E14.1 With ketoacidosis
0.762 0.238 0.000
E24 Cushing's syndrome
0.758 0.242 0.000
E14.2 Withrenal complications
0.752 0.248 0.000
E10.4 With neurological complications
0.750 0.250 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.747 0.252 0.000
K90.9 Intestinal malabsorption, unspecified
0.741 0.259 0.000
E31 Polyglandular dysfunction
0.734 0.266 0.000
E11.6 With other specified complications
0.723 0.277 0.000
E14.5 With peripheral circulatory complications
0.722 0.277 0.000
E23.0 Hypopituitarism
0.719 0.281 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.715 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.715 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
E05.5 Thyroid crisis or storm
0.715 0.285 0.000
E05.4 Thyrotoxicosis factitia
0.715 0.285 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.715 0.285 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.715 0.285 0.000
E27.2 Addisonian crisis
0.705 0.295 0.000
E14.7 With multiple complications
0.703 0.297 0.000
E14.0 With coma
0.703 0.297 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.299 0.701
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.299 0.701
E07.8 Other specified disorders of thyroid
0.699 0.301 0.000
E16.1 Other hypoglycaemia
0.699 0.301 0.000
E20.9 Hypoparathyroidism, unspecified
0.681 0.319 0.000
E25 Adrenogenital disorders
0.679 0.320 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.675 0.324 0.000
E32 Diseases of thymus
0.675 0.324 0.000
E30 Disorders of puberty, not elsewhere classified
0.675 0.324 0.000
N40-N51 Diseases of male genital organs
0.000 0.324 0.676
E07.9 Disorder of thyroid, unspecified
0.673 0.327 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.330 0.670
E40-E46 Malnutrition
0.669 0.331 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.665 0.335 0.000
N42 Other disorders of prostate
0.000 0.338 0.662
E27.5 Adrenomedullary hyperfunction
0.648 0.351 0.000
E27.0 Other adrenocortical overactivity
0.648 0.351 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.646 0.354 0.000
N42.8 Other specified disorders of prostate
0.000 0.357 0.643
E24.2 Drug-induced Cushing's syndrome
0.643 0.357 0.000
E11.0 With coma
0.642 0.358 0.000
K90.8 Other intestinal malabsorption
0.637 0.362 0.001
E14.8 With unspecified complications
0.636 0.364 0.000
E11.7 With multiple complications
0.634 0.366 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.631 0.369 0.000
E23.1 Drug-induced hypopituitarism
0.631 0.369 0.000
E05.8 Other thyrotoxicosis
0.628 0.372 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.625 0.374 0.000
N41 Inflammatory diseases of prostate
0.000 0.379 0.621
E28 Ovarian dysfunction
0.619 0.381 0.000
E23.6 Other disorders of pituitary gland
0.617 0.382 0.000
E03.5 Myxoedema coma
0.617 0.383 0.000
E03.4 Atrophy of thyroid (acquired)
0.617 0.383 0.000
E03.3 Postinfectious hypothyroidism
0.617 0.383 0.000
E03.1 Congenital hypothyroidism without goitre
0.617 0.383 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.616 0.384 0.000
K90.3 Pancreatic steatorrhoea
0.613 0.386 0.001
K90.2 Blind loop syndrome, not elsewhere classified
0.613 0.386 0.001
K90.1 Tropical sprue
0.613 0.386 0.001
E10.8 With unspecified complications
0.612 0.388 0.000
E07.1 Dyshormogenetic goitre
0.608 0.392 0.000
E07.0 Hypersecretion of calcitonin
0.608 0.392 0.000
E23.7 Disorder of pituitary gland, unspecified
0.604 0.396 0.000
E27.9 Disorder of adrenal gland, unspecified
0.599 0.401 0.000
E29 Testicular dysfunction
0.589 0.411 0.000
E24.0 Pituitary-dependent Cushing's disease
0.588 0.412 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.415 0.585
E31.0 Autoimmune polyglandular failure
0.584 0.416 0.000
E06 Thyroiditis
0.575 0.424 0.000
E26 Hyperaldosteronism
0.575 0.425 0.000
N46 Male infertility
0.000 0.426 0.574
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.430 0.570
N41.0 Acute prostatitis
0.000 0.430 0.570
E20.8 Other hypoparathyroidism
0.567 0.433 0.000
E20.1 Pseudohypoparathyroidism
0.567 0.433 0.000
E20.0 Idiopathic hypoparathyroidism
0.567 0.433 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.441 0.559
E11.1 With ketoacidosis
0.547 0.453 0.000
E13 Other specified diabetes mellitus
0.545 0.454 0.000
E24.8 Other Cushing's syndrome
0.544 0.456 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.544 0.456 0.000
E24.3 Ectopic ACTH syndrome
0.544 0.456 0.000
E24.1 Nelson's syndrome
0.544 0.456 0.000
E03.8 Other specified hypothyroidism
0.538 0.461 0.000
N44 Torsion of testis
0.000 0.462 0.538
N42.0 Calculus of prostate
0.000 0.463 0.537
E31.9 Polyglandular dysfunction, unspecified
0.526 0.474 0.000
E31.8 Other polyglandular dysfunction
0.526 0.474 0.000
E31.1 Polyglandular hyperfunction
0.526 0.474 0.000
E50-E64 Other nutritional deficiencies
0.519 0.480 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.513 0.487 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.513 0.487 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.513 0.487 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.513 0.487 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.513 0.487 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.513 0.487 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.513 0.487 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.513 0.487 0.000
N45 Orchitis and epididymitis
0.000 0.488 0.512
E34 Other endocrine disorders
0.493 0.507 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.491 0.509 0.000
E25.9 Adrenogenital disorder, unspecified
0.487 0.513 0.000
E25.8 Other adrenogenital disorders
0.487 0.513 0.000
E30.9 Disorder of puberty, unspecified
0.484 0.515 0.000
E30.8 Other disorders of puberty
0.484 0.515 0.000
E30.1 Precocious puberty
0.484 0.515 0.000
E30.0 Delayed puberty
0.484 0.515 0.000
E32.9 Disease of thymus, unspecified
0.484 0.515 0.000
E32.8 Other diseases of thymus
0.484 0.515 0.000
E32.1 Abscess of thymus
0.484 0.515 0.000
E32.0 Persistent hyperplasia of thymus
0.484 0.515 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.484 0.515 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.484 0.515 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.484 0.515 0.000
E11.8 With unspecified complications
0.481 0.519 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.479 0.520 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.479 0.520 0.000
E45 Retarded development following protein-energy malnutrition
0.479 0.520 0.000
E43 Unspecified severe protein-energy malnutrition
0.479 0.520 0.000
E42 Marasmic kwashiorkor
0.479 0.520 0.000
E41 Nutritional marasmus
0.479 0.520 0.000
E40 Kwashiorkor
0.479 0.520 0.000
N42.3 Dysplasia of prostate
0.000 0.525 0.475
N42.2 Atrophy of prostate
0.000 0.540 0.460
E28.3 Primary ovarian failure
0.459 0.541 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.544 0.456
E24.9 Cushing's syndrome, unspecified
0.450 0.550 0.000
N41.3 Prostatocystitis
0.000 0.554 0.446
N41.2 Abscess of prostate
0.000 0.554 0.446
E28.9 Ovarian dysfunction, unspecified
0.444 0.556 0.000
E28.8 Other ovarian dysfunction
0.444 0.556 0.000
E28.1 Androgen excess
0.444 0.556 0.000
E28.0 Oestrogen excess
0.444 0.556 0.000
E46 Unspecified protein-energy malnutrition
0.431 0.569 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.575 0.425
N41.8 Other inflammatory diseases of prostate
0.000 0.576 0.424
E29.9 Testicular dysfunction, unspecified
0.422 0.578 0.000
E29.8 Other testicular dysfunction
0.422 0.578 0.000
E29.0 Testicular hyperfunction
0.422 0.578 0.000
E22 Hyperfunction of pituitary gland
0.420 0.580 0.000
E06.5 Other chronic thyroiditis
0.417 0.583 0.000
E06.9 Thyroiditis, unspecified
0.416 0.584 0.000
E06.4 Drug-induced thyroiditis
0.413 0.587 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.413 0.587 0.000
E06.1 Subacute thyroiditis
0.413 0.587 0.000
E06.0 Acute thyroiditis
0.413 0.587 0.000
E26.9 Hyperaldosteronism, unspecified
0.412 0.588 0.000
E26.8 Other hyperaldosteronism
0.412 0.588 0.000
E26.1 Secondary hyperaldosteronism
0.412 0.588 0.000
E13.8 With unspecified complications
0.391 0.609 0.000
E13.7 With multiple complications
0.391 0.609 0.000
E13.6 With other specified complications
0.391 0.609 0.000
E13.5 With peripheral circulatory complications
0.391 0.609 0.000
E13.4 With neurological complications
0.391 0.609 0.000
E13.2 With renal complications
0.391 0.609 0.000
E13.1 With ketoacidosis
0.391 0.609 0.000
E13.0 With coma
0.391 0.609 0.000
E13.3 With ophthalmic complications
0.390 0.610 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.620 0.380
E61 Deficiency of other nutrient elements
0.380 0.620 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.377 0.623 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.372 0.627 0.000
E63 Other nutritional deficiencies
0.372 0.627 0.000
E56 Other vitamin deficiencies
0.372 0.627 0.000
E50 Vitamin A deficiency
0.372 0.627 0.000
E60 Dietary zinc deficiency
0.372 0.627 0.000
E59 Dietary selenium deficiency
0.372 0.627 0.000
E54 Ascorbic acid deficiency
0.372 0.627 0.000
E52 Niacin deficiency [pellagra]
0.372 0.627 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.633 0.366
E28.2 Polycystic ovarian syndrome
0.366 0.634 0.000
E51 Thiamine deficiency
0.365 0.635 0.000
E58 Dietary calcium deficiency
0.361 0.639 0.000
E11.2 With renal complications
0.355 0.645 0.000
E34.5 Androgen resistance syndrome
0.354 0.646 0.000
E34.4 Constitutional tall stature
0.354 0.646 0.000
E34.3 Short stature, not elsewhere classified
0.354 0.646 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.354 0.646 0.000
E34.1 Other hypersecretion of intestinal hormones
0.354 0.646 0.000
E34.8 Other specified endocrine disorders
0.346 0.653 0.000
E44.1 Mild protein-energy malnutrition
0.344 0.656 0.000
E44.0 Moderate protein-energy malnutrition
0.344 0.656 0.000
E53 Deficiency of other B group vitamins
0.341 0.659 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.664 0.336
E29.1 Testicular hypofunction
0.335 0.665 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.673 0.327
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.673 0.327
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.673 0.327
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.683 0.317
K40-K46 Hernia
0.000 0.688 0.312
E26.0 Primary hyperaldosteronism
0.311 0.689 0.000
E61.1 Iron deficiency
0.306 0.694 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.301 0.699 0.000
E22.8 Other hyperfunction of pituitary gland
0.301 0.699 0.000
E34.0 Carcinoid syndrome
0.300 0.699 0.000
N51.2 Balanitis in diseases classified elsewhere
0.000 0.701 0.298
N41.1 Chronic prostatitis
0.000 0.707 0.293
K41 Femoral hernia
0.000 0.707 0.293
E21.4 Other specified disorders of parathyroid gland
0.289 0.710 0.000
N43 Hydrocele and spermatocele
0.000 0.716 0.284
E65-E68 Obesity and other hyperalimentation
0.278 0.722 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.276 0.724 0.000
E61.9 Deficiency of nutrient element, unspecified
0.272 0.728 0.000
E61.8 Deficiency of other specified nutrient elements
0.272 0.728 0.000
E61.7 Deficiency of multiple nutrient elements
0.272 0.728 0.000
E61.6 Vanadium deficiency
0.272 0.728 0.000
E61.5 Molybdenum deficiency
0.272 0.728 0.000
E61.4 Chromium deficiency
0.272 0.728 0.000
E61.3 Manganese deficiency
0.272 0.728 0.000
E61.0 Copper deficiency
0.272 0.728 0.000
E34.9 Endocrine disorder, unspecified
0.271 0.729 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.270 0.729 0.000
E22.1 Hyperprolactinaemia
0.270 0.730 0.000
E21.2 Other hyperparathyroidism
0.268 0.731 0.000
E50.9 Vitamin A deficiency, unspecified
0.267 0.733 0.000
E50.8 Other manifestations of vitamin A deficiency
0.267 0.733 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.267 0.733 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.267 0.733 0.000
E50.5 Vitamin A deficiency with night blindness
0.267 0.733 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.267 0.733 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.267 0.733 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.267 0.733 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.267 0.733 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.267 0.733 0.000
E56.9 Vitamin deficiency, unspecified
0.267 0.733 0.000
E56.8 Deficiency of other vitamins
0.267 0.733 0.000
E56.1 Deficiency of vitamin K
0.267 0.733 0.000
E56.0 Deficiency of vitamin E
0.267 0.733 0.000
E63.9 Nutritional deficiency, unspecified
0.267 0.733 0.000
E63.8 Other specified nutritional deficiencies
0.267 0.733 0.000
E63.1 Imbalance of constituents of food intake
0.267 0.733 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.267 0.733 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.267 0.733 0.000
E64.8 Sequelae of other nutritional deficiencies
0.267 0.733 0.000
E64.3 Sequelae of rickets
0.267 0.733 0.000
E64.2 Sequelae of vitamin C deficiency
0.267 0.733 0.000
E64.1 Sequelae of vitamin A deficiency
0.267 0.733 0.000
E64.0 Sequelae of protein-energy malnutrition
0.267 0.733 0.000
N50 Other disorders of male genital organs
0.000 0.734 0.266
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.735 0.264
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.737 0.263
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.737 0.263
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.737 0.263
E51.9 Thiamine deficiency, unspecified
0.261 0.738 0.000
E51.8 Other manifestations of thiamine deficiency
0.261 0.738 0.000
E51.1 Beriberi
0.261 0.738 0.000
E06.3 Autoimmune thyroiditis
0.258 0.742 0.000
E11.4 With neurological complications
0.257 0.742 0.000
E55 Vitamin D deficiency
0.257 0.743 0.000
E51.2 Wernicke's encephalopathy
0.254 0.746 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.748 0.252
E53.1 Pyridoxine deficiency
0.245 0.755 0.000
E53.0 Riboflavin deficiency
0.245 0.755 0.000
E53.8 Deficiency of other specified B group vitamins
0.236 0.764 0.000
E27.8 Other specified disorders of adrenal gland
0.233 0.764 0.003
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.765 0.234
E61.2 Magnesium deficiency
0.234 0.766 0.000
K46 Unspecified abdominal hernia
0.000 0.770 0.229
E53.9 Vitamin B deficiency, unspecified
0.224 0.775 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.223 0.776 0.000
E21.3 Hyperparathyroidism, unspecified
0.223 0.776 0.000
E13.9 Without complications
0.223 0.777 0.001
N50.9 Disorder of male genital organs, unspecified
0.000 0.779 0.221
E11.9 Without complications
0.221 0.779 0.000
N48 Other disorders of penis
0.000 0.779 0.221
N50.0 Atrophy of testis
0.000 0.780 0.219
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.790 0.210
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.790 0.210
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.790 0.210
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.790 0.210
N48.4 Impotence of organic origin
0.000 0.793 0.207
N43.2 Other hydrocele
0.000 0.796 0.204
N43.1 Infected hydrocele
0.000 0.796 0.204
N43.0 Encysted hydrocele
0.000 0.796 0.204
E04 Other non-toxic goitre
0.202 0.798 0.000
K43 Ventral hernia
0.000 0.799 0.201
E67 Other hyperalimentation
0.199 0.800 0.000
E68 Sequelae of hyperalimentation
0.199 0.800 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.807 0.193
N48.1 Balanoposthitis
0.000 0.812 0.188
E55.0 Rickets, active
0.184 0.816 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.817 0.183
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.817 0.183
E22.0 Acromegaly and pituitary gigantism
0.175 0.825 0.001
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.835 0.165
N43.4 Spermatocele
0.000 0.838 0.162
K44 Diaphragmatic hernia
0.000 0.838 0.162
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.841 0.159
N48.2 Other inflammatory disorders of penis
0.000 0.841 0.159
K45 Other abdominal hernia
0.000 0.850 0.150
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.853 0.147
N48.5 Ulcer of penis
0.000 0.854 0.146
E04.8 Other specified non-toxic goitre
0.145 0.855 0.000
K75.4 Autoimmune hepatitis
0.145 0.855 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.856 0.144
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.856 0.144
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.856 0.144
K43.4 Parastomal hernia with gangrene
0.000 0.856 0.144
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.856 0.144
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.856 0.144
K43.1 Ventral hernia with gangrene
0.000 0.856 0.144
E67.8 Other specified hyperalimentation
0.143 0.857 0.000
E67.3 Hypervitaminosis D
0.143 0.857 0.000
E67.2 Megavitamin-B6 syndrome
0.143 0.857 0.000
E67.1 Hypercarotenaemia
0.143 0.857 0.000
E67.0 Hypervitaminosis A
0.143 0.857 0.000
E21.0 Primary hyperparathyroidism
0.143 0.857 0.000
K75 Other inflammatory liver diseases
0.137 0.863 0.000
N48.3 Priapism
0.000 0.864 0.136
K75.9 Inflammatory liver disease, unspecified
0.131 0.869 0.000
K75.8 Other specified inflammatory liver diseases
0.131 0.869 0.000
N48.0 Leukoplakia of penis
0.000 0.875 0.124
E04.9 Non-toxic goitre, unspecified
0.120 0.880 0.000
E04.0 Non-toxic diffuse goitre
0.118 0.882 0.000
E65 Localised adiposity
0.116 0.883 0.001
K44.1 Diaphragmatic hernia with gangrene
0.000 0.884 0.116
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.886 0.114
K90-K93 Other diseases of the digestive system
0.052 0.888 0.060
K42 Umbilical hernia
0.000 0.889 0.111
K45.1 Other specified abdominal hernia with gangrene
0.000 0.892 0.107
E04.1 Non-toxic single thyroid nodule
0.107 0.892 0.000
N43.3 Hydrocele, unspecified
0.000 0.900 0.100
K75.3 Granulomatous hepatitis, not elsewhere classified
0.098 0.902 0.000
K75.2 Nonspecific reactive hepatitis
0.098 0.902 0.000
K75.1 Phlebitis of portal vein
0.098 0.902 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.907 0.093
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.912 0.088
N39.0 Urinary tract infection, site not specified
0.000 0.918 0.082
K93 Disorders of other digestive organs in diseases classified elsewhere
0.038 0.919 0.043
K42.1 Umbilical hernia with gangrene
0.000 0.920 0.080
K92.0 Haematemesis
0.000 0.923 0.077
E83 Disorders of mineral metabolism
0.004 0.925 0.071
K92 Other diseases of digestive system
0.001 0.928 0.071
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.930 0.069
E55.9 Vitamin D deficiency, unspecified
0.068 0.932 0.000
N48.6 Balanitis xerotica obliterans
0.000 0.932 0.068
I83 Varicose veins of lower extremities
0.000 0.932 0.068
K50 Crohn's disease [regional enteritis]
0.000 0.934 0.066
T39.1 4-Aminophenol derivatives
0.000 0.934 0.066
K92.9 Disease of digestive system, unspecified
0.000 0.934 0.065
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.936 0.064
K50-K52 Noninfective enteritis and colitis
0.000 0.936 0.063
K75.0 Abscess of liver
0.063 0.937 0.000
M20.1 Hallux valgus (acquired)
0.000 0.937 0.063
K50.1 Crohn's disease of large intestine
0.000 0.938 0.062
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.938 0.062
K51 Ulcerative colitis
0.000 0.939 0.061
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.940 0.060
K50.8 Other Crohn's disease
0.000 0.940 0.060
T39.0 Salicylates
0.000 0.941 0.059
Chapter XI Diseases of the digestive system
0.001 0.941 0.059
K51.9 Ulcerative colitis, unspecified
0.000 0.941 0.059
N48.9 Disorder of penis, unspecified
0.001 0.941 0.058
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.942 0.058
K51.2 Ulcerative (chronic) proctitis
0.000 0.942 0.058
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.027 0.942 0.031
K93.1 Megacolon in Chagas' disease
0.027 0.942 0.031
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.027 0.942 0.031
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.944 0.056
K50.0 Crohn's disease of small intestine
0.000 0.944 0.056
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.945 0.054
K50.9 Crohn's disease, unspecified
0.000 0.946 0.054
E83.9 Disorder of mineral metabolism, unspecified
0.003 0.946 0.051
E83.8 Other disorders of mineral metabolism
0.003 0.946 0.051
E83.2 Disorders of zinc metabolism
0.003 0.946 0.051
E83.0 Disorders of copper metabolism
0.003 0.946 0.051
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.948 0.052
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.948 0.051
N39 Other disorders of urinary system
0.000 0.949 0.051
E83.3 Disorders of phosphorus metabolism
0.002 0.950 0.048
K51.4 Pseudopolyposis of colon
0.000 0.951 0.049
R47.0 Dysphasia and aphasia
0.048 0.952 0.000
N48.8 Other specified disorders of penis
0.000 0.953 0.047
N39.9 Disorder of urinary system, unspecified
0.000 0.953 0.047
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.953 0.047
K92.8 Other specified diseases of digestive system
0.001 0.954 0.045
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.954 0.046
T39.4 Antirheumatics, not elsewhere classified
0.000 0.954 0.046
T39.2 Pyrazolone derivatives
0.000 0.954 0.046
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.956 0.044
T42.4 Benzodiazepines
0.000 0.957 0.043
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.957 0.043
N50.1 Vascular disorders of male genital organs
0.000 0.957 0.043
N39.8 Other specified disorders of urinary system
0.000 0.959 0.041
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.959 0.041
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.960 0.040
K35-K38 Diseases of appendix
0.000 0.960 0.040
T50.8 Diagnostic agents
0.000 0.961 0.039
T50.7 Analeptics and opioid receptor antagonists
0.000 0.961 0.039
T50.5 Appetite depressants
0.000 0.961 0.039
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.961 0.039
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.961 0.039
T50.1 Loop [high-ceiling] diuretics
0.000 0.961 0.039
T50.0 Mineralocorticoids and their antagonists
0.000 0.961 0.039
E04.2 Non-toxic multinodular goitre
0.039 0.961 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.962 0.038
N30-N39 Other diseases of urinary system
0.000 0.962 0.038
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.962 0.037
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.963 0.037
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.963 0.037
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.963 0.037
K51.5 Mucosal proctocolitis
0.000 0.963 0.037
K51.8 Other ulcerative colitis
0.000 0.963 0.037
N39.2 Orthostatic proteinuria, unspecified
0.000 0.963 0.037
T50.4 Drugs affecting uric acid metabolism
0.000 0.964 0.036
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.964 0.036
N32.0 Bladder-neck obstruction
0.000 0.964 0.036
N32 Other disorders of bladder
0.000 0.964 0.036
T36 Poisoning by systemic antibiotics
0.000 0.964 0.035
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.965 0.035
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.965 0.035
T42.1 Iminostilbenes
0.000 0.965 0.035
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.965 0.035
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.965 0.035
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.965 0.035
R47 Speech disturbances, not elsewhere classified
0.035 0.965 0.000
N32.8 Other specified disorders of bladder
0.000 0.966 0.034
K37 Unspecified appendicitis
0.000 0.967 0.033
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.967 0.033
T42.2 Succinimides and oxazolidinediones
0.000 0.967 0.033
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.967 0.033
N39.1 Persistent proteinuria, unspecified
0.000 0.967 0.033
R47.1 Dysarthria and anarthria
0.033 0.967 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.967 0.033
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.967 0.033
K38 Other diseases of appendix
0.000 0.967 0.033
Z90.5 Acquired absence of kidney
0.000 0.967 0.033
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.967 0.032
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.968 0.032
Chapter XIV Diseases of the genitourinary system
0.000 0.968 0.032
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.968 0.032
N34 Urethritis and urethral syndrome
0.000 0.969 0.031
N32.2 Vesical fistula, not elsewhere classified
0.000 0.970 0.030
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.970 0.030
T45.0 Antiallergic and antiemetic drugs
0.000 0.970 0.030
N36 Other disorders of urethra
0.000 0.970 0.030
T42.3 Barbiturates
0.000 0.971 0.029
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.971 0.029
T45.8 Other primarily systemic and haematological agents
0.000 0.971 0.029
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.971 0.029

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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