TreeWAS – Variant ID: rs320

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I22 Subsequent myocardial infarction	0.000	0.001	0.999
I25.2 Old myocardial infarction	0.000	0.002	0.998
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.004	0.996
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.018	0.982
I71 Aortic aneurysm and dissection	0.000	0.024	0.976
I73 Other peripheral vascular diseases	0.000	0.025	0.975
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.026	0.974
I77 Other disorders of arteries and arterioles	0.000	0.028	0.972
I73.9 Peripheral vascular disease, unspecified	0.000	0.029	0.971
E78.0 Pure hypercholesterolaemia	0.000	0.034	0.966
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.035	0.964
I77.1 Stricture of artery	0.000	0.037	0.963
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.039	0.961
I24 Other acute ischaemic heart diseases	0.000	0.041	0.959
I21.9 Acute myocardial infarction, unspecified	0.000	0.045	0.955
E78.2 Mixed hyperlipidaemia	0.000	0.052	0.948
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.054	0.946
I21.4 Acute subendocardial myocardial infarction	0.000	0.071	0.929
I20 Angina pectoris	0.000	0.081	0.919
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.090	0.910
I71.0 Dissection of aorta [any part]	0.000	0.092	0.908
I73.8 Other specified peripheral vascular diseases	0.000	0.107	0.893
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.110	0.890
I25.5 Ischaemic cardiomyopathy	0.000	0.119	0.881
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.125	0.875
I20.0 Unstable angina	0.000	0.128	0.872
I70 Atherosclerosis	0.000	0.132	0.868
I25.4 Coronary artery aneurysm	0.000	0.133	0.867
E78.5 Hyperlipidaemia, unspecified	0.000	0.133	0.867
Chapter IX Diseases of the circulatory system	0.000	0.135	0.865
E78.4 Other hyperlipidaemia	0.000	0.137	0.863
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.141	0.859
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.141	0.859
I20.9 Angina pectoris, unspecified	0.000	0.150	0.850
E78.1 Pure hyperglyceridaemia	0.000	0.156	0.844
I77.8 Other specified disorders of arteries and arterioles	0.000	0.168	0.832
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.189	0.811
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.202	0.798
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.233	0.767
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.233	0.767
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.235	0.765
I77.0 Arteriovenous fistula, acquired	0.000	0.251	0.749
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.289	0.711
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.300	0.700
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.300	0.700
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.300	0.700
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.300	0.700
I77.5 Necrosis of artery	0.000	0.303	0.697
I77.4 Coeliac artery compression syndrome	0.000	0.303	0.697
I77.3 Arterial fibromuscular dysplasia	0.000	0.303	0.697
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.309	0.691
I77.2 Rupture of artery	0.000	0.310	0.690
E78.3 Hyperchylomicronaemia	0.000	0.311	0.689
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.313	0.687
I70.1 Atherosclerosis of renal artery	0.000	0.325	0.675
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.326	0.673
I74 Arterial embolism and thrombosis	0.000	0.341	0.659
I24.8 Other forms of acute ischaemic heart disease	0.000	0.343	0.657
E78.6 Lipoprotein deficiency	0.000	0.348	0.652
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.356	0.644
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.364	0.636
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.373	0.627
I79.1 Aortitis in diseases classified elsewhere	0.000	0.373	0.627
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.373	0.627
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.373	0.627
I00-I02 Acute rheumatic fever	0.000	0.378	0.622
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.389	0.611
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.392	0.608
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.393	0.607
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.403	0.597
I70.9 Generalised and unspecified atherosclerosis	0.000	0.411	0.589
I74.8 Embolism and thrombosis of other arteries	0.000	0.412	0.588
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.425	0.575
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.439	0.561
I70.0 Atherosclerosis of aorta	0.000	0.440	0.560
I70.8 Atherosclerosis of other arteries	0.000	0.449	0.550
I22.8 Subsequent myocardial infarction of other sites	0.000	0.455	0.545
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.464	0.536
I97.1 Other functional disturbances following cardiac surgery	0.000	0.466	0.534
I25.3 Aneurysm of heart	0.000	0.479	0.521
E78.8 Other disorders of lipoprotein metabolism	0.000	0.487	0.512
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.490	0.510
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.490	0.510
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.490	0.510
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.490	0.510
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.490	0.510
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.490	0.510
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.490	0.510
I77.6 Arteritis, unspecified	0.000	0.490	0.510
I24.1 Dressler's syndrome	0.000	0.493	0.506
I23.8 Other current complications following acute myocardial infarction	0.000	0.496	0.504
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.500	0.500
I20.1 Angina pectoris with documented spasm	0.000	0.502	0.498
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.516	0.484
I25.6 Silent myocardial ischaemia	0.001	0.523	0.476
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.525	0.475
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.541	0.458
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.544	0.456
I00 Rheumatic fever without mention of heart involvement	0.000	0.553	0.447
I02 Rheumatic chorea	0.000	0.554	0.446
I01 Rheumatic fever with heart involvement	0.000	0.554	0.446
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.564	0.436
I97.0 Postcardiotomy syndrome	0.000	0.564	0.436
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.571	0.429
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.572	0.428
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.578	0.422
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.590	0.410
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.590	0.410
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.598	0.402
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.605	0.395
I78 Diseases of capillaries	0.000	0.605	0.395
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.611	0.389
I74.5 Embolism and thrombosis of iliac artery	0.000	0.633	0.366
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.634	0.365
I99 Other and unspecified disorders of circulatory system	0.000	0.636	0.364
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.660	0.340
I70.80 Atherosclerosis of other arteries (without gangrene)	0.001	0.676	0.323
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.680	0.320
I01.8 Other acute rheumatic heart disease	0.000	0.680	0.320
I01.2 Acute rheumatic myocarditis	0.000	0.680	0.320
I01.1 Acute rheumatic endocarditis	0.000	0.680	0.320
I01.0 Acute rheumatic pericarditis	0.000	0.680	0.320
I02.9 Rheumatic chorea without heart involvement	0.000	0.680	0.320
I02.0 Rheumatic chorea with heart involvement	0.000	0.680	0.320
I05-I09 Chronic rheumatic heart diseases	0.000	0.687	0.313
I28 Other diseases of pulmonary vessels	0.000	0.689	0.311
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.692	0.308
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.706	0.294
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.706	0.294
I98.0 Cardiovascular syphilis	0.000	0.706	0.294
I78.9 Disease of capillaries, unspecified	0.000	0.717	0.283
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.720	0.280
I26 Pulmonary embolism	0.000	0.746	0.254
I07 Rheumatic tricuspid valve diseases	0.000	0.756	0.244
I78.8 Other diseases of capillaries	0.000	0.759	0.241
I28.8 Other specified diseases of pulmonary vessels	0.000	0.774	0.226
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.775	0.225
I09 Other rheumatic heart diseases	0.000	0.777	0.223
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.777	0.223
I28.1 Aneurysm of pulmonary artery	0.000	0.777	0.223
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.777	0.223
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.781	0.219
I05 Rheumatic mitral valve diseases	0.000	0.793	0.207
I27 Other pulmonary heart diseases	0.000	0.794	0.206
I07.1 Tricuspid insufficiency	0.000	0.806	0.194
I05.1 Rheumatic mitral insufficiency	0.000	0.816	0.184
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.821	0.179
I07.9 Tricuspid valve disease, unspecified	0.000	0.825	0.175
I07.8 Other tricuspid valve diseases	0.000	0.825	0.175
I07.2 Tricuspid stenosis with insufficiency	0.000	0.825	0.175
I07.0 Tricuspid stenosis	0.000	0.825	0.175
I72 Other aneurysm	0.001	0.829	0.170
I06 Rheumatic aortic valve diseases	0.000	0.830	0.170
I20.8 Other forms of angina pectoris	0.000	0.831	0.168
I09.8 Other specified rheumatic heart diseases	0.000	0.840	0.160
I09.2 Chronic rheumatic pericarditis	0.000	0.840	0.160
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.840	0.160
I09.0 Rheumatic myocarditis	0.000	0.840	0.160
I09.9 Rheumatic heart disease, unspecified	0.000	0.841	0.159
I27.9 Pulmonary heart disease, unspecified	0.000	0.848	0.152
I05.8 Other mitral valve diseases	0.000	0.851	0.148
I27.1 Kyphoscoliotic heart disease	0.000	0.852	0.148
I27.8 Other specified pulmonary heart diseases	0.000	0.861	0.139
I05.9 Mitral valve disease, unspecified	0.000	0.862	0.138
I72.9 Aneurysm of unspecified site	0.001	0.869	0.130
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.870	0.130
I05.0 Mitral stenosis	0.000	0.875	0.124
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.876	0.124
I72.2 Aneurysm of renal artery	0.001	0.876	0.123
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.877	0.122
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.877	0.122
Z95.1 Presence of aortocoronary bypass graft	0.000	0.877	0.123
I06.1 Rheumatic aortic insufficiency	0.000	0.877	0.122
I06.8 Other rheumatic aortic valve diseases	0.000	0.878	0.122
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.878	0.122
I10-I15 Hypertensive diseases	0.000	0.881	0.119
I27.0 Primary pulmonary hypertension	0.000	0.884	0.116
Z95.2 Presence of prosthetic heart valve	0.000	0.884	0.116
I72.1 Aneurysm of artery of upper extremity	0.001	0.886	0.113
I27.2 Other secondary pulmonary hypertension	0.000	0.891	0.109
I73.0 Raynaud's syndrome	0.000	0.892	0.107
I72.4 Aneurysm of artery of lower extremity	0.001	0.893	0.107
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.896	0.104
I06.0 Rheumatic aortic stenosis	0.001	0.897	0.102
I95 Hypotension	0.000	0.898	0.102
I78.1 Naevus, nonneoplastic	0.000	0.903	0.097
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.903	0.096
I05.2 Mitral stenosis with insufficiency	0.000	0.909	0.091
I11 Hypertensive heart disease	0.000	0.913	0.087
I72.3 Aneurysm of iliac artery	0.001	0.920	0.079
I15 Secondary hypertension	0.000	0.924	0.075
I13 Hypertensive heart and renal disease	0.000	0.924	0.075
N90 Other noninflammatory disorders of vulva and perineum	0.000	0.925	0.075
N90.4 Leukoplakia of vulva	0.000	0.925	0.075
I95.8 Other hypotension	0.000	0.926	0.074
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.929	0.071
N90.6 Hypertrophy of vulva	0.000	0.929	0.071
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.929	0.070
I95.0 Idiopathic hypotension	0.000	0.930	0.070
N90.7 Vulvar cyst	0.000	0.931	0.069
I72.8 Aneurysm of other specified arteries	0.001	0.931	0.068
N90.5 Atrophy of vulva	0.000	0.932	0.068
N90.1 Moderate vulvar dysplasia	0.000	0.941	0.059
I15.1 Hypertension secondary to other renal disorders	0.000	0.941	0.059
I72.0 Aneurysm of carotid artery	0.002	0.942	0.056
I08 Multiple valve diseases	0.000	0.944	0.056
N90.0 Mild vulvar dysplasia	0.000	0.945	0.055
I15.8 Other secondary hypertension	0.000	0.946	0.054
I15.2 Hypertension secondary to endocrine disorders	0.000	0.946	0.054
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.946	0.054
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.946	0.054
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.946	0.054
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.000	0.946	0.054
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.946	0.053
Z95.3 Presence of xenogenic heart valve	0.000	0.947	0.053
I08.8 Other multiple valve diseases	0.000	0.951	0.049
I15.9 Seconday hypertension, unspecified	0.000	0.953	0.047
I15.0 Renovascular hypertension	0.000	0.954	0.045
I08.9 Multiple valve disease, unspecified	0.000	0.955	0.044
I13.9 Hypertensive heart and renal disease, unspecified	0.001	0.956	0.044
I95.1 Orthostatic hypotension	0.000	0.958	0.042
N90.3 Dysplasia of vulva, unspecified	0.000	0.959	0.041
I95.2 Hypotension due to drugs	0.000	0.963	0.037
I12 Hypertensive renal disease	0.000	0.975	0.025
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.975	0.025
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.976	0.024
I95.9 Hypotension, unspecified	0.000	0.976	0.024
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.976	0.024
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.979	0.021
Z95.4 Presence of other heart-valve replacement	0.000	0.981	0.018
I81 Portal vein thrombosis	0.000	0.982	0.018
E70-E90 Metabolic disorders	0.000	0.982	0.018
I83 Varicose veins of lower extremities	0.000	0.983	0.017
E73 Lactose intolerance	0.000	0.985	0.015
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.985	0.015
S20.8 Superficial injuries of other and unspecified parts of thorax	0.015	0.985	0.000
E85 Amyloidosis	0.000	0.985	0.015
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.985	0.015
G50.0 Trigeminal neuralgia	0.000	0.985	0.015
I85 Oesophageal varices	0.000	0.986	0.014
I87 Other disorders of veins	0.000	0.986	0.014
E73.9 Lactose intolerance, unspecified	0.000	0.986	0.014
E79 Disorders of purine and pyrimidine metabolism	0.000	0.986	0.014
E84 Cystic fibrosis	0.000	0.986	0.013
I88 Nonspecific lymphadenitis	0.000	0.986	0.013
E85.4 Organ-limited amyloidosis	0.000	0.987	0.013
I08.0 Disorders of both mitral and aortic valves	0.000	0.987	0.013
E74 Other disorders of carbohydrate metabolism	0.000	0.987	0.013
I87.1 Compression of vein	0.000	0.987	0.013
E77 Disorders of glycoprotein metabolism	0.000	0.987	0.013
E76 Disorders of glycosaminoglycan metabolism	0.000	0.987	0.013
E72 Other disorders of amino-acid metabolism	0.000	0.987	0.013
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.987	0.013
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.987	0.013
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.988	0.012
E85.3 Secondary systemic amyloidosis	0.000	0.988	0.012
E70 Disorders of aromatic amino-acid metabolism	0.000	0.988	0.011
E73.8 Other lactose intolerance	0.000	0.989	0.011
E73.1 Secondary lactase deficiency	0.000	0.989	0.011
E73.0 Congenital lactase deficiency	0.000	0.989	0.011
I85.9 Oesophageal varices without bleeding	0.000	0.989	0.011
E85.9 Amyloidosis, unspecified	0.000	0.989	0.011
E85.8 Other amyloidosis	0.000	0.989	0.011
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.989	0.011
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.989	0.011
M25.57 Pain in joint (Ankle and foot)	0.000	0.989	0.011
E84.9 Cystic fibrosis, unspecified	0.000	0.989	0.011
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.989	0.011
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.990	0.010
I87.9 Disorder of vein, unspecified	0.000	0.990	0.010
I87.0 Postphlebitic syndrome	0.000	0.990	0.010
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.990	0.010
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.990	0.010
E79.1 Lesch-Nyhan syndrome	0.000	0.990	0.010
E84.8 Cystic fibrosis with other manifestations	0.000	0.990	0.010
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.990	0.010
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.990	0.010
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.990	0.010
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.990	0.010
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.990	0.009
I88.8 Other nonspecific lymphadenitis	0.000	0.990	0.009
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.990	0.009
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.990	0.009
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.990	0.009
E74.2 Disorders of galactose metabolism	0.000	0.990	0.009
E74.1 Disorders of fructose metabolism	0.000	0.990	0.009
E74.0 Glycogen storage disease	0.000	0.990	0.009
I87.8 Other specified disorders of veins	0.000	0.990	0.009
E71.3 Disorders of fatty-acid metabolism	0.000	0.991	0.009
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.991	0.009
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.991	0.009
E71.0 Maple-syrup-urine disease	0.000	0.991	0.009
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.991	0.009
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.991	0.009
E72.5 Disorders of glycine metabolism	0.000	0.991	0.009
E72.4 Disorders of ornithine metabolism	0.000	0.991	0.009
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.991	0.009
E72.2 Disorders of urea cycle metabolism	0.000	0.991	0.009
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.991	0.009
E72.0 Disorders of amino-acid transport	0.000	0.991	0.009
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.991	0.009
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.991	0.009
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.991	0.009
E76.2 Other mucopolysaccharidoses	0.000	0.991	0.009
E76.1 Mucopolysaccharidosis, type II	0.000	0.991	0.009
E76.0 Mucopolysaccharidosis, type I	0.000	0.991	0.009
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.991	0.009
E77.8 Other disorders of glycoprotein metabolism	0.000	0.991	0.009
E77.1 Defects in glycoprotein degradation	0.000	0.991	0.009
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.991	0.009
S20 Superficial injury of thorax	0.009	0.991	0.000
E88 Other metabolic disorders	0.000	0.991	0.009
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.991	0.009
S20.2 Contusion of thorax	0.009	0.991	0.000
E75.6 Lipid storage disorder, unspecified	0.000	0.991	0.009
E75.5 Other lipid storage disorders	0.000	0.991	0.009
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.991	0.009
E75.3 Sphingolipidosis, unspecified	0.000	0.991	0.009
E75.1 Other gangliosidosis	0.000	0.991	0.009
E75.0 GM2 gangliosidosis	0.000	0.991	0.009
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.991	0.008
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.991	0.008
E70.2 Disorders of tyrosine metabolism	0.000	0.991	0.008
E70.1 Other hyperphenylalaninaemias	0.000	0.991	0.008
E70.0 Classical phenylketonuria	0.000	0.991	0.008
I85.0 Oesophageal varices with bleeding	0.000	0.991	0.008
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.991	0.009
E80.4 Gilbert's syndrome	0.000	0.992	0.008
R16.1 Splenomegaly, not elsewhere classified	0.008	0.992	0.000
E80.2 Other porphyria	0.000	0.992	0.008
M07.30 Other psoriatic arthropathies (Multiple sites)	0.008	0.992	0.000
E75.2 Other sphingolipidosis	0.000	0.992	0.008
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.992	0.008
E80.5 Crigler-Najjar syndrome	0.000	0.992	0.008
E80.3 Defects of catalase and peroxydase	0.000	0.992	0.008
E80.0 Hereditary erythropoietic porphyria	0.000	0.992	0.008
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.992	0.008
E70.3 Albinism	0.000	0.993	0.007
E80.1 Porphyria cutanea tarda	0.000	0.993	0.007
N85.1 Endometrial adenomatous hyperplasia	0.007	0.993	0.000
I51.9 Heart disease, unspecified	0.000	0.993	0.007
I80 Phlebitis and thrombophlebitis	0.000	0.993	0.007
E88.3 Tumour lysis syndrome	0.000	0.993	0.007
S20.7 Multiple superficial injuries of thorax	0.007	0.993	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.993	0.007
S20.0 Contusion of breast	0.007	0.993	0.000
G50 Disorders of trigeminal nerve	0.000	0.993	0.007
S20.1 Other and unspecified superficial injuries of breast	0.007	0.993	0.000
M07.3 Other psoriatic arthropathies	0.007	0.993	0.000
E88.8 Other specified metabolic disorders	0.000	0.993	0.006
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.006	0.994	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.994	0.006
E86 Volume depletion	0.000	0.994	0.006
S20.4 Other superficial injuries of back wall of thorax	0.006	0.994	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.994	0.006
E88.9 Metabolic disorder, unspecified	0.000	0.994	0.006
I86 Varicose veins of other sites	0.000	0.994	0.006
E88.2 Lipomatosis, not elsewhere classified	0.000	0.994	0.006
I84.4 External haemorrhoids with other complications	0.000	0.994	0.006
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.994	0.006
G50.1 Atypical facial pain	0.000	0.994	0.006
S20.3 Other superficial injuries of front wall of thorax	0.005	0.994	0.000
S06.2 Diffuse brain injury	0.000	0.994	0.006
I89.1 Lymphangitis	0.000	0.994	0.006
M07.34 Other psoriatic arthropathies (Hand)	0.005	0.994	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.995	0.005
I12.9 Hypertensive renal disease without renal failure	0.001	0.995	0.004
G50.8 Other disorders of trigeminal nerve	0.000	0.995	0.005
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.995	0.005
E80.6 Other disorders of bilirubin metabolism	0.001	0.995	0.005
S06 Intracranial injury	0.000	0.995	0.005
M07.38 Other psoriatic arthropathies (Other)	0.005	0.995	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.005	0.995	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.005	0.995	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.005	0.995	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.995	0.005
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.995	0.005
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.995	0.005
G50.9 Disorder of trigeminal nerve, unspecified	0.000	0.995	0.005
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.995	0.005
S06.3 Focal brain injury	0.000	0.995	0.005
M07.36 Other psoriatic arthropathies (Lower leg)	0.005	0.995	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.005	0.995	0.000
D47.2 Monoclonal gammopathy	0.000	0.995	0.005
M07.39 Other psoriatic arthropathies (Site unspecified)	0.005	0.995	0.000
I60-I69 Cerebrovascular diseases	0.000	0.995	0.005
I86.3 Vulval varices	0.000	0.995	0.004
I86.0 Sublingual varices	0.000	0.995	0.004
C02.1 Border of tongue	0.005	0.995	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.005	0.995	0.000
I82 Other venous embolism and thrombosis	0.000	0.995	0.004
C06.0 Cheek mucosa	0.005	0.995	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.995	0.004
S06.8 Other intracranial injuries	0.000	0.995	0.004
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.996	0.004
O00.1 Tubal pregnancy	0.004	0.996	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.996	0.004
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.996	0.004
S06.9 Intracranial injury, unspecified	0.000	0.996	0.004
C02 Malignant neoplasm of other and unspecified parts of tongue	0.004	0.996	0.000
E11.5 With peripheral circulatory complications	0.000	0.996	0.004
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.996	0.004
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.996	0.004
S06.4 Epidural haemorrhage	0.000	0.996	0.004
S06.5 Traumatic subdural haemorrhage	0.000	0.996	0.004
C06 Malignant neoplasm of other and unspecified parts of mouth	0.004	0.996	0.000
W19.4 Street and highway	0.004	0.996	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.996	0.004
S06.7 Intracranial injury with prolonged coma	0.000	0.996	0.004
S06.1 Traumatic cerebral oedema	0.000	0.996	0.004
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.996	0.004
I86.2 Pelvic varices	0.000	0.996	0.003
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.996	0.004
S00.0 Superficial injury of scalp	0.000	0.996	0.004
I63 Cerebral infarction	0.000	0.996	0.004
C02.9 Tongue, unspecified	0.004	0.996	0.000
I86.1 Scrotal varices	0.000	0.996	0.004
Z93.5 Cystostomy status	0.000	0.996	0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.996	0.004
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.004	0.996	0.000
I86.8 Varicose veins of other specified sites	0.000	0.996	0.003
I82.1 Thrombophlebitis migrans	0.000	0.996	0.003
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.996	0.003
C06.2 Retromolar area	0.003	0.996	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.996	0.003
E11.9 Without complications	0.000	0.996	0.004
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.996	0.003
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.997	0.003
I86.4 Gastric varices	0.000	0.997	0.003
C00 Malignant neoplasm of lip	0.003	0.997	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.997	0.003
C02.2 Ventral surface of tongue	0.003	0.997	0.000
S63.6 Sprain and strain of finger(s)	0.000	0.997	0.003
C07 Malignant neoplasm of parotid gland	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
Z95.0 Presence of cardiac pacemaker	0.000	0.997	0.003
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.003
E11 Non-insulin-dependent diabetes mellitus	0.000	0.997	0.003
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.997	0.003
C00.0 External upper lip	0.003	0.997	0.000
C02.8 Overlapping lesion of tongue	0.003	0.997	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.003	0.997	0.000
C02.0 Dorsal surface of tongue	0.003	0.997	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.997	0.003
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.997	0.003
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
I68.0 Cerebral amyloid angiopathy	0.000	0.997	0.003
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.997	0.003
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.003	0.997	0.000
C06.1 Vestibule of mouth	0.003	0.997	0.000
I82.3 Embolism and thrombosis of renal vein	0.000	0.997	0.003
M07 Psoriatic and enteropathic arthropathies	0.003	0.997	0.000
E11.1 With ketoacidosis	0.000	0.997	0.003
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.997	0.003
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.997	0.003
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.997	0.003
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.997	0.003
S06.0 Concussion	0.000	0.997	0.003
C03 Malignant neoplasm of gum	0.003	0.997	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.997	0.003
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.997	0.003
C15.5 Lower third of oesophagus	0.000	0.997	0.003
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.997	0.003
I82.0 Budd-Chiari syndrome	0.000	0.997	0.003
C10 Malignant neoplasm of oropharynx	0.003	0.997	0.000
C04 Malignant neoplasm of floor of mouth	0.003	0.997	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.003
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.997	0.003
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
C02.4 Lingual tonsil	0.003	0.997	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.997	0.003
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.997	0.003
E11.3 With ophthalmic complications	0.000	0.997	0.003
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.997	0.003
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.003	0.997	0.000
C06.9 Mouth, unspecified	0.003	0.997	0.000
I63.8 Other cerebral infarction	0.000	0.997	0.003
I65.1 Occlusion and stenosis of basilar artery	0.000	0.997	0.003
J36 Peritonsillar abscess	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.997	0.003
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.997	0.003
E89.5 Postprocedural testicular hypofunction	0.000	0.997	0.003
E89.1 Postprocedural hypoinsulinaemia	0.000	0.997	0.003
I65.2 Occlusion and stenosis of carotid artery	0.000	0.997	0.003
C00.9 Lip, unspecified	0.003	0.997	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.003
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.997	0.003
C00.1 External lower lip	0.003	0.997	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.997	0.003
C03.1 Lower gum	0.003	0.997	0.000
C11 Malignant neoplasm of nasopharynx	0.003	0.997	0.000
C05 Malignant neoplasm of palate	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations