TreeWAS – Variant ID: rs3218816

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E10.9 Without complications	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000
E11.9 Without complications	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
E10.3 With ophthalmic complications	0.996	0.004
M06.9 Rheumatoid arthritis, unspecified	0.965	0.035
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.961	0.039
E10.1 With ketoacidosis	0.948	0.052
M06 Other rheumatoid arthritis	0.929	0.071
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.921	0.079
E11.3 With ophthalmic complications	0.915	0.085
M05-M14 Inflammatory polyarthropathies	0.891	0.109
E10.5 With peripheral circulatory complications	0.887	0.113
M05 Seropositive rheumatoid arthritis	0.882	0.118
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.877	0.123
M05.9 Seropositive rheumatoid arthritis, unspecified	0.876	0.124
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.865	0.135
E10.4 With neurological complications	0.857	0.143
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.844	0.156
E10.0 With coma	0.829	0.171
E10.2 With renal complications	0.802	0.198
E11.2 With renal complications	0.793	0.207
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.786	0.214
E11.4 With neurological complications	0.779	0.221
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.779	0.221
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.775	0.225
E11.0 With coma	0.759	0.241
M06.3 Rheumatoid nodule	0.758	0.242
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.747	0.253
E14 Unspecified diabetes mellitus	0.742	0.258
E11.1 With ketoacidosis	0.722	0.278
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E11.8 With unspecified complications	0.717	0.283
E11.7 With multiple complications	0.717	0.283
E11.6 With other specified complications	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.696	0.304
M06.98 Rheumatoid arthritis, unspecified (Other)	0.692	0.308
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.686	0.314
M10 Gout	0.670	0.329
M06.8 Other specified rheumatoid arthritis	0.666	0.334
M06.4 Inflammatory polyarthropathy	0.666	0.334
M06.2 Rheumatoid bursitis	0.666	0.334
M06.1 Adult-onset Still's disease	0.666	0.334
E13 Other specified diabetes mellitus	0.665	0.335
M06.0 Seronegative rheumatoid arthritis	0.663	0.337
M14 Arthropathies in other diseases classified elsewhere	0.639	0.361
M12 Other specific arthropathies	0.639	0.361
M09 Juvenile arthritis in diseases classified elsewhere	0.639	0.361
M08 Juvenile arthritis	0.639	0.361
M06.34 Rheumatoid nodule (Hand)	0.636	0.364
M05.8 Other seropositive rheumatoid arthritis	0.632	0.367
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.632	0.367
M05.2 Rheumatoid vasculitis	0.632	0.367
M05.1 Rheumatoid lung disease	0.632	0.367
M05.0 Felty's syndrome	0.632	0.367
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.628	0.372
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.628	0.372
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.628	0.372
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.628	0.372
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.628	0.372
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.628	0.372
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.628	0.372
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.628	0.372
M11 Other crystal arthropathies	0.626	0.374
Chapter IV Endocrine, nutritional and metabolic diseases	0.618	0.382
E11.5 With peripheral circulatory complications	0.601	0.398
E14.3 With ophthalmic complications	0.586	0.414
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.564	0.436
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.549	0.451
M06.39 Rheumatoid nodule (Site unspecified)	0.544	0.456
M06.38 Rheumatoid nodule (Other)	0.544	0.456
M06.37 Rheumatoid nodule (Ankle and foot)	0.544	0.456
M06.36 Rheumatoid nodule (Lower leg)	0.544	0.456
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.544	0.456
M06.33 Rheumatoid nodule (Forearm)	0.544	0.456
M06.32 Rheumatoid nodule (Upper arm)	0.544	0.456
M06.31 Rheumatoid nodule (Shoulder region)	0.544	0.456
M06.30 Rheumatoid nodule (Multiple sites)	0.544	0.456
E14.8 With unspecified complications	0.532	0.468
E14.7 With multiple complications	0.532	0.468
E14.6 With other specified complications	0.532	0.468
E14.5 With peripheral circulatory complications	0.532	0.468
E14.4 With neurological complications	0.532	0.468
E14.2 Withrenal complications	0.532	0.468
E14.1 With ketoacidosis	0.532	0.468
E14.0 With coma	0.532	0.468
E20-E35 Disorders of other endocrine glands	0.528	0.472
E16 Other disorders of pancreatic internal secretion	0.526	0.474
M07 Psoriatic and enteropathic arthropathies	0.521	0.479
E12.9 Without complications	0.514	0.486
E12.8 With unspecified complications	0.514	0.486
E12.7 With multiple complications	0.514	0.486
E12.6 With other specified complications	0.514	0.486
E12.5 With peripheral circulatory complications	0.514	0.486
E12.4 With neurological complications	0.514	0.486
E12.3 With ophthalmic complications	0.514	0.486
E12.2 With renal complications	0.514	0.486
E12.1 With ketoacidosis	0.514	0.486
E12.0 With coma	0.514	0.486
M10.9 Gout, unspecified	0.513	0.487
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.508	0.492
E16.2 Hypoglycaemia, unspecified	0.498	0.502
E14.9 Without complications	0.494	0.506
M13 Other arthritis	0.486	0.514
M10.4 Other secondary gout	0.481	0.519
M10.3 Gout due to impairment of renal function	0.481	0.519
M10.2 Drug-induced gout	0.481	0.519
M10.1 Lead-induced gout	0.481	0.519
M10.0 Idiopathic gout	0.481	0.519
M06.19 Adult-onset Still's disease (Site unspecified)	0.478	0.522
M06.18 Adult-onset Still's disease (Other)	0.478	0.522
M06.17 Adult-onset Still's disease (Ankle and foot)	0.478	0.522
M06.16 Adult-onset Still's disease (Lower leg)	0.478	0.522
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.478	0.522
M06.14 Adult-onset Still's disease (Hand)	0.478	0.522
M06.13 Adult-onset Still's disease (Forearm)	0.478	0.522
M06.12 Adult-onset Still's disease (Upper arm)	0.478	0.522
M06.11 Adult-onset Still's disease (Shoulder region)	0.478	0.522
M06.10 Adult-onset Still's disease (Multiple sites)	0.478	0.522
M06.29 Rheumatoid bursitis (Site unspecified)	0.478	0.522
M06.28 Rheumatoid bursitis (Other)	0.478	0.522
M06.27 Rheumatoid bursitis (Ankle and foot)	0.478	0.522
M06.26 Rheumatoid bursitis (Lower leg)	0.478	0.522
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.478	0.522
M06.24 Rheumatoid bursitis (Hand)	0.478	0.522
M06.23 Rheumatoid bursitis (Forearm)	0.478	0.522
M06.22 Rheumatoid bursitis (Upper arm)	0.478	0.522
M06.21 Rheumatoid bursitis (Shoulder region)	0.478	0.522
M06.20 Rheumatoid bursitis (Multiple sites)	0.478	0.522
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.478	0.522
M06.48 Inflammatory polyarthropathy (Other)	0.478	0.522
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.478	0.522
M06.46 Inflammatory polyarthropathy (Lower leg)	0.478	0.522
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.478	0.522
M06.44 Inflammatory polyarthropathy (Hand)	0.478	0.522
M06.43 Inflammatory polyarthropathy (Forearm)	0.478	0.522
M06.42 Inflammatory polyarthropathy (Upper arm)	0.478	0.522
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.478	0.522
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.478	0.522
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.478	0.522
M06.88 Other specified rheumatoid arthritis (Other)	0.478	0.522
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.478	0.522
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.478	0.522
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.478	0.522
M06.84 Other specified rheumatoid arthritis (Hand)	0.478	0.522
M06.83 Other specified rheumatoid arthritis (Forearm)	0.478	0.522
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.478	0.522
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.478	0.522
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.478	0.522
E13.8 With unspecified complications	0.477	0.523
E13.7 With multiple complications	0.477	0.523
E13.6 With other specified complications	0.477	0.523
E13.5 With peripheral circulatory complications	0.477	0.523
E13.4 With neurological complications	0.477	0.523
E13.3 With ophthalmic complications	0.477	0.523
E13.2 With renal complications	0.477	0.523
E13.1 With ketoacidosis	0.477	0.523
E13.0 With coma	0.477	0.523
M06.08 Seronegative rheumatoid arthritis (Other)	0.475	0.525
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.475	0.525
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.475	0.525
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.475	0.525
M06.04 Seronegative rheumatoid arthritis (Hand)	0.475	0.525
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.475	0.525
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.475	0.525
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.475	0.525
M80-M85 Disorders of bone density and structure	0.473	0.527
E50-E64 Other nutritional deficiencies	0.468	0.532
M08.9 Juvenile arthritis, unspecified	0.458	0.542
M08.8 Other juvenile arthritis	0.458	0.542
M08.4 Pauciarticular juvenile arthritis	0.458	0.542
M08.3 Juvenile polyarthritis (seronegative)	0.458	0.542
M08.2 Juvenile arthritis with systemic onset	0.458	0.542
M08.1 Juvenile ankylosing spondylitis	0.458	0.542
M08.0 Juvenile rheumatoid arthritis	0.458	0.542
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.458	0.542
M09.2 Juvenile arthritis in ulcerative colitis	0.458	0.542
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.458	0.542
M09.0 Juvenile arthritis in psoriasis	0.458	0.542
M12.8 Other specific arthropathies, not elsewhere classified	0.458	0.542
M12.5 Traumatic arthropathy	0.458	0.542
M12.4 Intermittent hydrarthrosis	0.458	0.542
M12.3 Palindromic rheumatism	0.458	0.542
M12.2 Villonodular synovitis (pigmented)	0.458	0.542
M12.1 Kaschin-Beck disease	0.458	0.542
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.458	0.542
M14.8 Arthropathies in other specified diseases classified elsewhere	0.458	0.542
M14.6 Neuropathic arthropathy	0.458	0.542
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.458	0.542
M14.4 Arthropathy in amyloidosis	0.458	0.542
M14.3 Lipoid dermatoarthritis	0.458	0.542
M14.2 Diabetic arthropathy	0.458	0.542
M14.1 Crystal arthropathy in other metabolic disorders	0.458	0.542
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.458	0.542
M05.09 Felty's syndrome (Site unspecified)	0.453	0.546
M05.08 Felty's syndrome (Other)	0.453	0.546
M05.07 Felty's syndrome (Ankle and foot)	0.453	0.546
M05.06 Felty's syndrome (Lower leg)	0.453	0.546
M05.05 Felty's syndrome (Pelvic region and thigh)	0.453	0.546
M05.04 Felty's syndrome (Hand)	0.453	0.546
M05.03 Felty's syndrome (Forearm)	0.453	0.546
M05.02 Felty's syndrome (Upper arm)	0.453	0.546
M05.01 Felty's syndrome (Shoulder region)	0.453	0.546
M05.00 Felty's syndrome (Multiple sites)	0.453	0.546
M05.19 Rheumatoid lung disease (Site unspecified)	0.453	0.546
M05.18 Rheumatoid lung disease (Other)	0.453	0.546
M05.17 Rheumatoid lung disease (Ankle and foot)	0.453	0.546
M05.16 Rheumatoid lung disease (Lower leg)	0.453	0.546
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.453	0.546
M05.14 Rheumatoid lung disease (Hand)	0.453	0.546
M05.13 Rheumatoid lung disease (Forearm)	0.453	0.546
M05.12 Rheumatoid lung disease (Upper arm)	0.453	0.546
M05.11 Rheumatoid lung disease (Shoulder region)	0.453	0.546
M05.10 Rheumatoid lung disease (Multiple sites)	0.453	0.546
M05.29 Rheumatoid vasculitis (Site unspecified)	0.453	0.546
M05.28 Rheumatoid vasculitis (Other)	0.453	0.546
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.453	0.546
M05.26 Rheumatoid vasculitis (Lower leg)	0.453	0.546
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.453	0.546
M05.24 Rheumatoid vasculitis (Hand)	0.453	0.546
M05.23 Rheumatoid vasculitis (Forearm)	0.453	0.546
M05.22 Rheumatoid vasculitis (Upper arm)	0.453	0.546
M05.21 Rheumatoid vasculitis (Shoulder region)	0.453	0.546
M05.20 Rheumatoid vasculitis (Multiple sites)	0.453	0.546
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.453	0.546
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.453	0.546
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.453	0.546
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.453	0.546
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.453	0.546
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.453	0.546
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.453	0.546
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.453	0.546
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.453	0.546
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.453	0.546
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.453	0.546
M05.88 Other seropositive rheumatoid arthritis (Other)	0.453	0.546
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.453	0.546
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.453	0.546
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.453	0.546
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.453	0.546
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.453	0.546
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.453	0.546
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.453	0.546
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.453	0.546
M11.9 Crystal arthropathy, unspecified	0.449	0.551
M11.8 Other specified crystal arthropathies	0.449	0.551
M11.1 Familial chondrocalcinosis	0.449	0.551
M11.0 Hydroxyapatite deposition disease	0.449	0.551
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.443	0.557
M65-M68 Disorders of synovium and tendon	0.443	0.557
M11.2 Other chondrocalcinosis	0.436	0.564
M84 Disorders of continuity of bone	0.435	0.565
M91-M94 Chondropathies	0.434	0.566
E29 Testicular dysfunction	0.431	0.569
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.431	0.569
M70-M79 Other soft tissue disorders	0.430	0.570
M60-M63 Disorders of muscles	0.426	0.574
E13.9 Without complications	0.424	0.575
M86-M90 Other osteopathies	0.414	0.586
E22 Hyperfunction of pituitary gland	0.408	0.591
M00-M03 Infectious arthropathies	0.408	0.592
E15 Nondiabetic hypoglycaemic coma	0.404	0.596
E40-E46 Malnutrition	0.404	0.596
M10.99 Gout, unspecified (Site unspecified)	0.400	0.600
M65 Synovitis and tenosynovitis	0.398	0.602
M10.97 Gout, unspecified (Ankle and foot)	0.396	0.604
M40-M43 Deforming dorsopathies	0.393	0.607
M20-M25 Other joint disorders	0.392	0.608
# Top node	0.392	0.608
Chapter VIII Diseases of the ear and mastoid process	0.389	0.611
M84.0 Malunion of fracture	0.388	0.612
M79 Other soft tissue disorders, not elsewhere classified	0.387	0.613
E53 Deficiency of other B group vitamins	0.385	0.615
E23 Hypofunction and other disorders of pituitary gland	0.379	0.621
E21.3 Hyperparathyroidism, unspecified	0.379	0.621
E35 Disorders of endocrine glands in diseases classified elsewhere	0.378	0.621
E34 Other endocrine disorders	0.378	0.621
E32 Diseases of thymus	0.378	0.621
E31 Polyglandular dysfunction	0.378	0.621
E30 Disorders of puberty, not elsewhere classified	0.378	0.621
E26 Hyperaldosteronism	0.378	0.621
E25 Adrenogenital disorders	0.378	0.621
E20 Hypoparathyroidism	0.378	0.621
E16.9 Disorder of pancreatic internal secretion, unspecified	0.377	0.623
E16.8 Other specified disorders of pancreatic internal secretion	0.377	0.623
E16.4 Abnormal secretion of gastrin	0.377	0.623
E16.3 Increased secretion of glucagon	0.377	0.623
E16.1 Other hypoglycaemia	0.377	0.623
E16.0 Drug-induced hypoglycaemia without coma	0.377	0.623
E24 Cushing's syndrome	0.376	0.624
H65-H75 Diseases of middle ear and mastoid	0.375	0.625
M07.6 Other enteropathic arthropathies	0.374	0.626
M07.5 Arthropathy in ulcerative colitis	0.374	0.626
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.374	0.626
M07.2 Psoriatic spondylitis	0.374	0.626
M07.1 Arthritis mutilans	0.374	0.626
M07.0 Distal interphalangeal psoriatic arthropathy	0.374	0.626
M10.98 Gout, unspecified (Other)	0.367	0.632
M10.95 Gout, unspecified (Pelvic region and thigh)	0.367	0.632
M10.94 Gout, unspecified (Hand)	0.367	0.632
M10.93 Gout, unspecified (Forearm)	0.367	0.632
M10.92 Gout, unspecified (Upper arm)	0.367	0.632
M10.91 Gout, unspecified (Shoulder region)	0.367	0.632
M10.90 Gout, unspecified (Multiple sites)	0.367	0.632
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.366	0.634
M84.1 Nonunion of fracture [pseudarthrosis]	0.365	0.635
E28 Ovarian dysfunction	0.364	0.636
E29.1 Testicular hypofunction	0.362	0.638
M35 Other systemic involvement of connective tissue	0.362	0.638
M79.0 Rheumatism, unspecified	0.357	0.643
M94 Other disorders of cartilage	0.352	0.648
M77 Other enthesopathies	0.351	0.649
M85 Other disorders of bone density and structure	0.350	0.650
M13.0 Polyarthritis, unspecified	0.350	0.650
M13.8 Other specified arthritis	0.348	0.651
M13.1 Monoarthritis, not elsewhere classified	0.348	0.651
M65.3 Trigger finger	0.348	0.652
M79.1 Myalgia	0.346	0.654
E65-E68 Obesity and other hyperalimentation	0.346	0.654
M10.09 Idiopathic gout (Site unspecified)	0.345	0.655
M10.08 Idiopathic gout (Other)	0.345	0.655
M10.07 Idiopathic gout (Ankle and foot)	0.345	0.655
M10.06 Idiopathic gout (Lower leg)	0.345	0.655
M10.05 Idiopathic gout (Pelvic region and thigh)	0.345	0.655
M10.04 Idiopathic gout (Hand)	0.345	0.655
M10.03 Idiopathic gout (Forearm)	0.345	0.655
M10.02 Idiopathic gout (Upper arm)	0.345	0.655
M10.01 Idiopathic gout (Shoulder region)	0.345	0.655
M10.00 Idiopathic gout (Multiple sites)	0.345	0.655
M10.19 Lead-induced gout (Site unspecified)	0.345	0.655
M10.18 Lead-induced gout (Other)	0.345	0.655
M10.17 Lead-induced gout (Ankle and foot)	0.345	0.655
M10.16 Lead-induced gout (Lower leg)	0.345	0.655
M10.15 Lead-induced gout (Pelvic region and thigh)	0.345	0.655
M10.14 Lead-induced gout (Hand)	0.345	0.655
M10.13 Lead-induced gout (Forearm)	0.345	0.655
M10.12 Lead-induced gout (Upper arm)	0.345	0.655
M10.11 Lead-induced gout (Shoulder region)	0.345	0.655
M10.10 Lead-induced gout (Multiple sites)	0.345	0.655
M10.29 Drug-induced gout (Site unspecified)	0.345	0.655
M10.28 Drug-induced gout (Other)	0.345	0.655
M10.27 Drug-induced gout (Ankle and foot)	0.345	0.655
M10.26 Drug-induced gout (Lower leg)	0.345	0.655
M10.25 Drug-induced gout (Pelvic region and thigh)	0.345	0.655
M10.24 Drug-induced gout (Hand)	0.345	0.655
M10.23 Drug-induced gout (Forearm)	0.345	0.655
M10.22 Drug-induced gout (Upper arm)	0.345	0.655
M10.21 Drug-induced gout (Shoulder region)	0.345	0.655
M10.20 Drug-induced gout (Multiple sites)	0.345	0.655
M10.39 Gout due to impairment of renal function (Site unspecified)	0.345	0.655
M10.38 Gout due to impairment of renal function (Other)	0.345	0.655
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.345	0.655
M10.36 Gout due to impairment of renal function (Lower leg)	0.345	0.655
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.345	0.655
M10.34 Gout due to impairment of renal function (Hand)	0.345	0.655
M10.33 Gout due to impairment of renal function (Forearm)	0.345	0.655
M10.32 Gout due to impairment of renal function (Upper arm)	0.345	0.655
M10.31 Gout due to impairment of renal function (Shoulder region)	0.345	0.655
M10.30 Gout due to impairment of renal function (Multiple sites)	0.345	0.655
M10.49 Other secondary gout (Site unspecified)	0.345	0.655
M10.48 Other secondary gout (Other)	0.345	0.655
M10.47 Other secondary gout (Ankle and foot)	0.345	0.655
M10.46 Other secondary gout (Lower leg)	0.345	0.655
M10.45 Other secondary gout (Pelvic region and thigh)	0.345	0.655
M10.44 Other secondary gout (Hand)	0.345	0.655
M10.43 Other secondary gout (Forearm)	0.345	0.655
M10.42 Other secondary gout (Upper arm)	0.345	0.655
M10.41 Other secondary gout (Shoulder region)	0.345	0.655
M10.40 Other secondary gout (Multiple sites)	0.345	0.655
M83 Adult osteomalacia	0.339	0.661
M82 Osteoporosis in diseases classified elsewhere	0.339	0.661
M84.03 Malunion of fracture (Forearm)	0.338	0.661
M62 Other disorders of muscle	0.338	0.662
E64 Sequelae of malnutrition and other nutritional deficiencies	0.336	0.664
E63 Other nutritional deficiencies	0.336	0.664
E56 Other vitamin deficiencies	0.336	0.664
E51 Thiamine deficiency	0.336	0.664
E50 Vitamin A deficiency	0.336	0.664
E60 Dietary zinc deficiency	0.336	0.664
E59 Dietary selenium deficiency	0.336	0.664
E58 Dietary calcium deficiency	0.336	0.664
E54 Ascorbic acid deficiency	0.336	0.664
E52 Niacin deficiency [pellagra]	0.336	0.664
M89 Other disorders of bone	0.335	0.665
H73 Other disorders of tympanic membrane	0.335	0.665
M45-M49 Spondylopathies	0.333	0.667
E22.0 Acromegaly and pituitary gigantism	0.332	0.668
H60-H62 Diseases of external ear	0.332	0.668
M10.96 Gout, unspecified (Lower leg)	0.331	0.669
M80 Osteoporosis with pathological fracture	0.331	0.669
E27 Other disorders of adrenal gland	0.329	0.671
H90-H95 Other disorders of ear	0.329	0.671
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.328	0.671
M08.08 Juvenile rheumatoid arthritis (Other)	0.328	0.671
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.328	0.671
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.328	0.671
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.328	0.671
M08.04 Juvenile rheumatoid arthritis (Hand)	0.328	0.671
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.328	0.671
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.328	0.671
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.328	0.671
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.328	0.671
M08.19 Juvenile ankylosing spondylitis (Site unspecified)	0.328	0.671
M08.18 Juvenile ankylosing spondylitis (Other)	0.328	0.671
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)	0.328	0.671
M08.16 Juvenile ankylosing spondylitis (Lower leg)	0.328	0.671
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)	0.328	0.671
M08.14 Juvenile ankylosing spondylitis (Hand)	0.328	0.671
M08.13 Juvenile ankylosing spondylitis (Forearm)	0.328	0.671
M08.12 Juvenile ankylosing spondylitis (Upper arm)	0.328	0.671
M08.11 Juvenile ankylosing spondylitis (Shoulder region)	0.328	0.671
M08.10 Juvenile ankylosing spondylitis (Multiple sites)	0.328	0.671
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.328	0.671
M08.28 Juvenile arthritis with systemic onset (Other)	0.328	0.671
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)	0.328	0.671
M08.26 Juvenile arthritis with systemic onset (Lower leg)	0.328	0.671
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)	0.328	0.671
M08.24 Juvenile arthritis with systemic onset (Hand)	0.328	0.671
M08.23 Juvenile arthritis with systemic onset (Forearm)	0.328	0.671
M08.22 Juvenile arthritis with systemic onset (Upper arm)	0.328	0.671
M08.21 Juvenile arthritis with systemic onset (Shoulder region)	0.328	0.671
M08.20 Juvenile arthritis with systemic onset (Multiple sites)	0.328	0.671
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)	0.328	0.671
M08.38 Juvenile polyarthritis (seronegative) (Other)	0.328	0.671
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)	0.328	0.671
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)	0.328	0.671
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)	0.328	0.671
M08.34 Juvenile polyarthritis (seronegative) (Hand)	0.328	0.671
M08.33 Juvenile polyarthritis (seronegative) (Forearm)	0.328	0.671
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)	0.328	0.671
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)	0.328	0.671
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)	0.328	0.671
M08.49 Pauciarticular juvenile arthritis (Site unspecified)	0.328	0.671
M08.48 Pauciarticular juvenile arthritis (Other)	0.328	0.671
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)	0.328	0.671
M08.46 Pauciarticular juvenile arthritis (Lower leg)	0.328	0.671
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)	0.328	0.671
M08.44 Pauciarticular juvenile arthritis (Hand)	0.328	0.671
M08.43 Pauciarticular juvenile arthritis (Forearm)	0.328	0.671
M08.42 Pauciarticular juvenile arthritis (Upper arm)	0.328	0.671
M08.41 Pauciarticular juvenile arthritis (Shoulder region)	0.328	0.671
M08.40 Pauciarticular juvenile arthritis (Multiple sites)	0.328	0.671
M08.89 Other juvenile arthritis (Site unspecified)	0.328	0.671
M08.88 Other juvenile arthritis (Other)	0.328	0.671
M08.87 Other juvenile arthritis (Ankle and foot)	0.328	0.671
M08.86 Other juvenile arthritis (Lower leg)	0.328	0.671
M08.85 Other juvenile arthritis (Pelvic region and thigh)	0.328	0.671
M08.84 Other juvenile arthritis (Hand)	0.328	0.671
M08.83 Other juvenile arthritis (Forearm)	0.328	0.671
M08.82 Other juvenile arthritis (Upper arm)	0.328	0.671
M08.81 Other juvenile arthritis (Shoulder region)	0.328	0.671
M08.80 Other juvenile arthritis (Multiple sites)	0.328	0.671
M08.99 Juvenile arthritis, unspecified (Site unspecified)	0.328	0.671
M08.98 Juvenile arthritis, unspecified (Other)	0.328	0.671
M08.97 Juvenile arthritis, unspecified (Ankle and foot)	0.328	0.671
M08.96 Juvenile arthritis, unspecified (Lower leg)	0.328	0.671
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)	0.328	0.671
M08.94 Juvenile arthritis, unspecified (Hand)	0.328	0.671
M08.93 Juvenile arthritis, unspecified (Forearm)	0.328	0.671
M08.92 Juvenile arthritis, unspecified (Upper arm)	0.328	0.671
M08.91 Juvenile arthritis, unspecified (Shoulder region)	0.328	0.671
M08.90 Juvenile arthritis, unspecified (Multiple sites)	0.328	0.671
M09.09 Juvenile arthritis in psoriasis (Site unspecified)	0.328	0.671
M09.08 Juvenile arthritis in psoriasis (Other)	0.328	0.671
M09.07 Juvenile arthritis in psoriasis (Ankle and foot)	0.328	0.671
M09.06 Juvenile arthritis in psoriasis (Lower leg)	0.328	0.671
M09.05 Juvenile arthritis in psoriasis (Pelvic region and thigh)	0.328	0.671
M09.04 Juvenile arthritis in psoriasis (Hand)	0.328	0.671
M09.03 Juvenile arthritis in psoriasis (Forearm)	0.328	0.671
M09.02 Juvenile arthritis in psoriasis (Upper arm)	0.328	0.671
M09.01 Juvenile arthritis in psoriasis (Shoulder region)	0.328	0.671
M09.00 Juvenile arthritis in psoriasis (Multiple sites)	0.328	0.671
M09.19 Juvenile arthritis in Crohn's disease [regional enteritis] (Site unspecified)	0.328	0.671
M09.18 Juvenile arthritis in Crohn's disease [regional enteritis] (Other)	0.328	0.671
M09.17 Juvenile arthritis in Crohn's disease [regional enteritis] (Ankle and foot)	0.328	0.671
M09.16 Juvenile arthritis in Crohn's disease [regional enteritis] (Lower leg)	0.328	0.671
M09.15 Juvenile arthritis in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.328	0.671
M09.14 Juvenile arthritis in Crohn's disease [regional enteritis] (Hand)	0.328	0.671
M09.13 Juvenile arthritis in Crohn's disease [regional enteritis] (Forearm)	0.328	0.671
M09.12 Juvenile arthritis in Crohn's disease [regional enteritis] (Upper arm)	0.328	0.671
M09.11 Juvenile arthritis in Crohn's disease [regional enteritis] (Shoulder region)	0.328	0.671
M09.10 Juvenile arthritis in Crohn's disease [regional enteritis] (Multiple sites)	0.328	0.671
M09.29 Juvenile arthritis in ulcerative colitis (Site unspecified)	0.328	0.671
M09.28 Juvenile arthritis in ulcerative colitis (Other)	0.328	0.671
M09.27 Juvenile arthritis in ulcerative colitis (Ankle and foot)	0.328	0.671
M09.26 Juvenile arthritis in ulcerative colitis (Lower leg)	0.328	0.671
M09.25 Juvenile arthritis in ulcerative colitis (Pelvic region and thigh)	0.328	0.671
M09.24 Juvenile arthritis in ulcerative colitis (Hand)	0.328	0.671
M09.23 Juvenile arthritis in ulcerative colitis (Forearm)	0.328	0.671
M09.22 Juvenile arthritis in ulcerative colitis (Upper arm)	0.328	0.671
M09.21 Juvenile arthritis in ulcerative colitis (Shoulder region)	0.328	0.671
M09.20 Juvenile arthritis in ulcerative colitis (Multiple sites)	0.328	0.671
M09.89 Juvenile arthritis in other diseases classified elsewhere (Site unspecified)	0.328	0.671
M09.88 Juvenile arthritis in other diseases classified elsewhere (Other)	0.328	0.671
M09.87 Juvenile arthritis in other diseases classified elsewhere (Ankle and foot)	0.328	0.671
M09.86 Juvenile arthritis in other diseases classified elsewhere (Lower leg)	0.328	0.671

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations