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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34457396
log Bayes Factor = 18.3682
Chromosome 19   position 10,752,352  (GRCh37) Explore rs34457396 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
G90-G99 Other disorders of the nervous system
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.996 0.004 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.995 0.005 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.994 0.006 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.992 0.008 0.000
I30-I52 Other forms of heart disease
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.987 0.013 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.985 0.015 0.000
Z71.8 Other specified counselling
0.983 0.017 0.000
Chapter II Neoplasms
0.980 0.020 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.978 0.022 0.000
I35 Nonrheumatic aortic valve disorders
0.977 0.023 0.000
B95-B98 Bacterial, viral and other infectious agents
0.977 0.023 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.975 0.025 0.000
G95 Other diseases of spinal cord
0.975 0.025 0.000
C15-C26 Malignant neoplasms of digestive organs
0.970 0.030 0.000
C18 Malignant neoplasm of colon
0.968 0.032 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.964 0.036 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.963 0.037 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.961 0.039 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.961 0.039 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.960 0.040 0.000
Chapter X Diseases of the respiratory system
0.958 0.042 0.000
Z12 Special screening examination for neoplasms
0.958 0.042 0.000
Z95.2 Presence of prosthetic heart valve
0.952 0.048 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.950 0.050 0.000
Z36 Antenatal screening
0.949 0.051 0.000
Z95.1 Presence of aortocoronary bypass graft
0.948 0.052 0.000
Z37 Outcome of delivery
0.946 0.054 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.944 0.056 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.938 0.062 0.000
C18.7 Sigmoid colon
0.933 0.067 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.930 0.070 0.000
I71 Aortic aneurysm and dissection
0.925 0.075 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.925 0.075 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.924 0.076 0.000
Chapter XX External causes of morbidity and mortality
0.922 0.078 0.000
Z37.2 Twins, both liveborn
0.912 0.088 0.000
J90-J94 Other diseases of pleura
0.910 0.090 0.000
G95.1 Vascular myelopathies
0.910 0.090 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.909 0.091 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.903 0.097 0.000
J93 Pneumothorax
0.900 0.100 0.000
O85-O92 Complications predominantly related to the puerperium
0.899 0.101 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.898 0.102 0.000
Z94 Transplanted organ and tissue status
0.896 0.104 0.000
J30-J39 Other diseases of upper respiratory tract
0.896 0.104 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.894 0.106 0.000
I51 Complications and ill-defined descriptions of heart disease
0.894 0.106 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.892 0.108 0.000
C18.9 Colon, unspecified
0.892 0.108 0.000
I74 Arterial embolism and thrombosis
0.891 0.109 0.000
C18.2 Ascending colon
0.890 0.110 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.889 0.111 0.000
Z34 Supervision of normal pregnancy
0.886 0.114 0.000
I35.0 Aortic (valve) stenosis
0.884 0.116 0.000
I31 Other diseases of pericardium
0.883 0.117 0.000
B35-B49 Mycoses
0.880 0.120 0.000
Z95.4 Presence of other heart-valve replacement
0.880 0.120 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.880 0.120 0.000
Z89 Acquired absence of limb
0.874 0.126 0.000
J93.9 Pneumothorax, unspecified
0.872 0.128 0.000
C92 Myeloid leukaemia
0.870 0.130 0.000
Z80 Family history of malignant neoplasm
0.867 0.133 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.866 0.134 0.000
Z35 Supervision of high-risk pregnancy
0.865 0.135 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.864 0.136 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.859 0.141 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.859 0.141 0.000
J30 Vasomotor and allergic rhinitis
0.856 0.144 0.000
Z36.9 Antenatal screening, unspecified
0.854 0.146 0.000
Z72 Problems related to lifestyle
0.852 0.148 0.000
Z39 Postpartum care and examination
0.851 0.149 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.851 0.149 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.851 0.149 0.000
C18.6 Descending colon
0.849 0.151 0.000
C18.4 Transverse colon
0.848 0.152 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.847 0.153 0.000
I44 Atrioventricular and left bundle-branch block
0.845 0.155 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.841 0.159 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.841 0.159 0.000
G95.2 Cord compression, unspecified
0.841 0.159 0.000
I20 Angina pectoris
0.840 0.160 0.000
C07 Malignant neoplasm of parotid gland
0.840 0.160 0.000
Z74 Problems related to care-provider dependency
0.839 0.161 0.000
G40-G47 Episodic and paroxysmal disorders
0.839 0.161 0.000
Z83 Family history of other specific disorders
0.839 0.161 0.000
I45 Other conduction disorders
0.838 0.162 0.000
G96 Other disorders of central nervous system
0.837 0.163 0.000
B37 Candidiasis
0.835 0.165 0.000
I25.5 Ischaemic cardiomyopathy
0.832 0.168 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.827 0.173 0.000
I10-I15 Hypertensive diseases
0.826 0.174 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.825 0.175 0.000
G90 Disorders of autonomic nervous system
0.825 0.175 0.000
I33 Acute and subacute endocarditis
0.825 0.175 0.000
I78 Diseases of capillaries
0.823 0.177 0.000
I46 Cardiac arrest
0.823 0.177 0.000
G95.9 Disease of spinal cord, unspecified
0.822 0.178 0.000
Z72.0 Tobacco use
0.821 0.179 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.821 0.179 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.817 0.183 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.812 0.188 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.812 0.188 0.000
I20.0 Unstable angina
0.811 0.189 0.000
B15-B19 Viral hepatitis
0.810 0.190 0.000
C20 Malignant neoplasm of rectum
0.810 0.190 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.810 0.190 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.807 0.193 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.805 0.195 0.000
C85.1 B-cell lymphoma, unspecified
0.802 0.198 0.000
O90 Complications of the puerperium, not elsewhere classified
0.802 0.198 0.000
J95-J99 Other diseases of the respiratory system
0.801 0.199 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.800 0.200 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.800 0.200 0.000
Z83.3 Family history of diabetes mellitus
0.800 0.200 0.000
I51.7 Cardiomegaly
0.799 0.201 0.000
I22 Subsequent myocardial infarction
0.799 0.201 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.798 0.202 0.000
Z31 Procreative management
0.798 0.202 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.797 0.203 0.000
I45.1 Other and unspecified right bundle-branch block
0.796 0.204 0.000
I44.0 Atrioventricular block, first degree
0.793 0.207 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.793 0.207 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.792 0.208 0.000
I44.1 Atrioventricular block, second degree
0.792 0.208 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.792 0.208 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.791 0.209 0.000
Z34.8 Supervision of other normal pregnancy
0.789 0.211 0.000
C45 Mesothelioma
0.787 0.213 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.787 0.213 0.000
I31.3 Pericardial effusion (noninflammatory)
0.786 0.214 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.784 0.216 0.000
J38.3 Other diseases of vocal cords
0.784 0.216 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.783 0.217 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.781 0.219 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.777 0.223 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.777 0.223 0.000
O30 Multiple gestation
0.776 0.224 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.774 0.226 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.773 0.227 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.772 0.228 0.000
I12 Hypertensive renal disease
0.771 0.229 0.000
Q50-Q56 Congenital malformations of genital organs
0.770 0.230 0.000
J93.1 Other spontaneous pneumothorax
0.769 0.231 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.767 0.233 0.000
O42 Premature rupture of membranes
0.767 0.233 0.000
Z57 Occupational exposure to risk-factors
0.767 0.233 0.000
O47 False labour
0.765 0.235 0.000
J30.1 Allergic rhinitis due to pollen
0.765 0.235 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.764 0.236 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.763 0.237 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.763 0.237 0.000
Chapter XXII Codes for special purposes
0.759 0.241 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.758 0.242 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.757 0.243 0.000
I71.0 Dissection of aorta [any part]
0.757 0.243 0.000
G95.0 Syringomyelia and syringobulbia
0.757 0.243 0.000
J86 Pyothorax
0.756 0.244 0.000
I36 Nonrheumatic tricuspid valve disorders
0.756 0.244 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.755 0.245 0.000
Z39.0 Care and examination immediately after delivery
0.755 0.245 0.000
C92.0 Acute myeloid leukaemia
0.754 0.246 0.000
I51.9 Heart disease, unspecified
0.753 0.247 0.000
B37.0 Candidal stomatitis
0.752 0.248 0.000
Z76 Persons encountering health services in other circumstances
0.751 0.249 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.750 0.250 0.000
J39 Other diseases of upper respiratory tract
0.750 0.250 0.000
Z94.7 Corneal transplant status
0.749 0.251 0.000
Z71.9 Counselling, unspecified
0.749 0.251 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.748 0.252 0.000
I25.3 Aneurysm of heart
0.748 0.252 0.000
J30.4 Allergic rhinitis, unspecified
0.747 0.253 0.000
I30 Acute pericarditis
0.747 0.253 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.746 0.254 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.746 0.254 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.746 0.254 0.000
I74.5 Embolism and thrombosis of iliac artery
0.743 0.256 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.743 0.256 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.743 0.257 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.743 0.257 0.000
O32.1 Maternal care for breech presentation
0.743 0.257 0.000
O32.8 Maternal care for other malpresentation of foetus
0.742 0.258 0.000
Z29 Need for other prophylactic measures
0.742 0.258 0.000
I35.9 Aortic valve disorder, unspecified
0.740 0.259 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.740 0.259 0.000
Z63 Other problems related to primary support group, including family circumstances
0.740 0.260 0.000
O86 Other puerperal infections
0.740 0.260 0.000
Q80-Q89 Other congenital malformations
0.740 0.260 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.737 0.263 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.736 0.264 0.000
A15-A19 Tuberculosis
0.734 0.266 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.732 0.268 0.000
Z84 Family history of other conditions
0.732 0.268 0.000
Z82.3 Family history of stroke
0.731 0.269 0.000
C12 Malignant neoplasm of pyriform sinus
0.731 0.269 0.000
C92.1 Chronic myeloid leukaemia
0.731 0.269 0.000
D00-D09 In situ neoplasms
0.730 0.270 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.728 0.271 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.728 0.272 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.728 0.272 0.000
B50-B64 Protozoal diseases
0.728 0.272 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.727 0.273 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.727 0.273 0.000
J93.8 Other pneumothorax
0.726 0.274 0.000
I46.9 Cardiac arrest, unspecified
0.726 0.274 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.726 0.274 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.725 0.275 0.000
Y52 Agents primarily affecting the cardiovascular system
0.724 0.276 0.000
J35 Chronic diseases of tonsils and adenoids
0.722 0.278 0.000
J60-J70 Lung diseases due to external agents
0.721 0.279 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.721 0.279 0.000
Z36.8 Other antenatal screening
0.720 0.280 0.000
Z71.6 Tobacco abuse counselling
0.720 0.280 0.000
I24 Other acute ischaemic heart diseases
0.719 0.281 0.000
A80-A89 Viral infections of the central nervous system
0.719 0.281 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.719 0.281 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.718 0.282 0.000
V80-V89 Other land transport accidents
0.718 0.282 0.000
I12.9 Hypertensive renal disease without renal failure
0.717 0.282 0.000
Z94.4 Liver transplant status
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.284 0.000
G83 Other paralytic syndromes
0.715 0.285 0.000
B02 Zoster [herpes zoster]
0.715 0.285 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.715 0.285 0.000
G92 Toxic encephalopathy
0.715 0.285 0.000
Z38 Liveborn infants according to place of birth
0.714 0.286 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.714 0.286 0.000
Q23 Congenital malformations of aortic and mitral valves
0.713 0.287 0.000
G96.0 Cerebrospinal fluid leak
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
I31.1 Chronic constrictive pericarditis
0.713 0.287 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.713 0.287 0.000
Z82.2 Family history of deafness and hearing loss
0.713 0.287 0.000
Z82.1 Family history of blindness and visual loss
0.713 0.287 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.711 0.289 0.000
I48 Atrial fibrillation and flutter
0.711 0.289 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.711 0.289 0.000
I41 Myocarditis in diseases classified elsewhere
0.711 0.289 0.000
I40 Acute myocarditis
0.711 0.289 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.711 0.289 0.000
I32 Pericarditis in diseases classified elsewhere
0.711 0.289 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.711 0.289 0.000
C17 Malignant neoplasm of small intestine
0.710 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
I37 Pulmonary valve disorders
0.709 0.290 0.000
O85 Puerperal sepsis
0.709 0.291 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
Z71.7 Human immunodeficiency virus [HIV] counselling
0.708 0.292 0.000
Z71.5 Drug abuse counselling and surveillance
0.708 0.292 0.000
Z71.4 Alcohol abuse counselling and surveillance
0.708 0.292 0.000
Z71.0 Person consulting on behalf of another person
0.708 0.292 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.706 0.294 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.706 0.294 0.000
O90.8 Other complications of the puerperium, not elsewhere classified
0.706 0.294 0.000
I33.0 Acute and subacute infective endocarditis
0.706 0.294 0.000
Z95.3 Presence of xenogenic heart valve
0.705 0.294 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.704 0.295 0.000
I51.6 Cardiovascular disease, unspecified
0.703 0.296 0.000
Z75 Problems related to medical facilities and other health care
0.703 0.297 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.702 0.298 0.000
O32.3 Maternal care for face, brow and chin presentation
0.701 0.299 0.000
Z74.0 Reduced mobility
0.701 0.299 0.000
J94 Other pleural conditions
0.700 0.300 0.000
B00 Herpesviral [herpes simplex] infections
0.700 0.300 0.000
Z35.5 Supervision of elderly primigravida
0.700 0.300 0.000
A00-A09 Intestinal infectious diseases
0.699 0.300 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.699 0.301 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.699 0.301 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.699 0.301 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.699 0.301 0.000
Z89.5 Acquired absence of leg at or below knee
0.699 0.301 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.698 0.302 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.698 0.302 0.000
J93.0 Spontaneous tension pneumothorax
0.696 0.304 0.000
Z95.0 Presence of cardiac pacemaker
0.695 0.305 0.000
C83.3 Large cell (diffuse)
0.695 0.305 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.694 0.306 0.000
C18.8 Overlapping lesion of colon
0.694 0.306 0.000
C83.1 Small cleaved cell (diffuse)
0.694 0.306 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.693 0.307 0.000
Q00-Q07 Congenital malformations of the nervous system
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.693 0.307 0.000
Y00-Y09 Assault
0.692 0.308 0.000
O30.0 Twin pregnancy
0.692 0.308 0.000
Z89.4 Acquired absence of foot and ankle
0.692 0.308 0.000
Z10 Routine general health check-up of defined subpopulation
0.691 0.309 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.691 0.309 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.690 0.309 0.000
Z94.1 Heart transplant status
0.690 0.310 0.000
J30.3 Other allergic rhinitis
0.689 0.311 0.000
I35.8 Other aortic valve disorders
0.688 0.312 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.688 0.312 0.000
C95 Leukaemia of unspecified cell type
0.688 0.312 0.000
C94 Other leukaemias of specified cell type
0.688 0.312 0.000
C93 Monocytic leukaemia
0.688 0.312 0.000
C88 Malignant immunoproliferative diseases
0.688 0.312 0.000
C86 Other specified types of T/NK-cell lymphoma
0.688 0.312 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.688 0.312 0.000
I45.8 Other specified conduction disorders
0.688 0.312 0.000
B37.9 Candidiasis, unspecified
0.688 0.312 0.000
C23 Malignant neoplasm of gallbladder
0.687 0.313 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.687 0.313 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.687 0.313 0.000
Z12.3 Special screening examination for neoplasm of breast
0.687 0.313 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.687 0.313 0.000
B37.8 Candidiasis of other sites
0.685 0.315 0.000
Z99.8 Dependence on other enabling machines and devices
0.684 0.316 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.684 0.316 0.000
V40-V49 Car occupant injured in transport accident
0.684 0.316 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.683 0.317 0.000
Z99.1 Dependence on respirator
0.683 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.319 0.000
I78.1 Naevus, nonneoplastic
0.680 0.320 0.000
Z36.5 Antenatal screening for isoimmunisation
0.680 0.320 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.680 0.320 0.000
Z37.9 Outcome of delivery unspecified
0.678 0.322 0.000
Z37.7 Other multiple births, all stillborn
0.678 0.322 0.000
Z37.6 Other multiple births, some liveborn
0.678 0.322 0.000
Z37.5 Other multiple births, all liveborn
0.678 0.322 0.000
Z37.4 Twins, both stillborn
0.678 0.322 0.000
Z37.3 Twins, one liveborn and one stillborn
0.678 0.322 0.000
Z37.1 Single stillbirth
0.678 0.322 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.678 0.322 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.677 0.323 0.000
Z89.2 Acquired absence of upper limb above wrist
0.676 0.323 0.000
Z83.6 Family history of diseases of the respiratory system
0.676 0.324 0.000
G44 Other headache syndromes
0.676 0.324 0.000
Z71.2 Person consulting for explanation of investigation findings
0.675 0.324 0.000
Z99.3 Dependence on wheelchair
0.675 0.325 0.000
G90.2 Horner's syndrome
0.674 0.326 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.674 0.326 0.000
X50-X57 Overexertion, travel and privation
0.672 0.328 0.000
C04 Malignant neoplasm of floor of mouth
0.671 0.329 0.000
J95.8 Other postprocedural respiratory disorders
0.671 0.329 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.670 0.330 0.000
Z37.0 Single live birth
0.669 0.331 0.000
J38.4 Oedema of larynx
0.669 0.331 0.000
B99-B99 Other infectious diseases
0.669 0.331 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.668 0.332 0.000
Z94.0 Kidney transplant status
0.668 0.332 0.000
C18.1 Appendix
0.668 0.332 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.668 0.332 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.668 0.332 0.000
I35.1 Aortic (valve) insufficiency
0.667 0.333 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.667 0.333 0.000
Q35-Q37 Cleft lip and cleft palate
0.667 0.333 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.667 0.333 0.000
Z29.0 Isolation
0.667 0.333 0.000
X60-X84 Intentional self-harm
0.666 0.334 0.000
Z57.2 Occupational exposure to dust
0.666 0.334 0.000
I21.9 Acute myocardial infarction, unspecified
0.666 0.334 0.000
Q51 Congenital malformations of uterus and cervix
0.664 0.336 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.663 0.336 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.663 0.336 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.663 0.336 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.663 0.336 0.000
C45.9 Mesothelioma, unspecified
0.664 0.336 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.662 0.338 0.000
I74.8 Embolism and thrombosis of other arteries
0.661 0.339 0.000
Y35-Y36 Legal intervention and operations of war
0.661 0.339 0.000
Y10-Y34 Event of undetermined intent
0.661 0.339 0.000
X85-X99 Assault
0.661 0.339 0.000
X30-X39 Exposure to forces of nature
0.661 0.339 0.000
X10-X19 Contact with heat and hot substances
0.661 0.339 0.000
X00-X09 Exposure to smoke, fire and flames
0.661 0.339 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.661 0.339 0.000
W75-W84 Other accidental threats to breathing
0.661 0.339 0.000
W65-W74 Accidental drowning and submersion
0.661 0.339 0.000
V95-V97 Air and space transport accidents
0.661 0.339 0.000
V90-V94 Water transport accidents
0.661 0.339 0.000
V70-V79 Bus occupant injured in transport accident
0.661 0.339 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.661 0.339 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.661 0.339 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.661 0.339 0.000
G95.8 Other specified diseases of spinal cord
0.659 0.341 0.000
J39.2 Other diseases of pharynx
0.659 0.341 0.000
Q27 Other congenital malformations of peripheral vascular system
0.659 0.341 0.000
J92 Pleural plaque
0.659 0.341 0.000
Z00.0 General medical examination
0.658 0.342 0.000
G45.3 Amaurosis fugax
0.658 0.342 0.000
B18 Chronic viral hepatitis
0.658 0.342 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.658 0.342 0.000
I21.4 Acute subendocardial myocardial infarction
0.657 0.343 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.656 0.344 0.000
J85 Abscess of lung and mediastinum
0.655 0.345 0.000
Z94.8 Other transplanted organ and tissue status
0.655 0.345 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.655 0.345 0.000
G81 Hemiplegia
0.654 0.346 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.653 0.347 0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.653 0.347 0.000
I15 Secondary hypertension
0.652 0.348 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.651 0.348 0.000
C46 Kaposi's sarcoma
0.651 0.348 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.650 0.350 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.650 0.350 0.000
C81 Hodgkin's disease
0.648 0.351 0.000
D04 Carcinoma in situ of skin
0.648 0.352 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.647 0.353 0.000
C85.0 Lymphosarcoma
0.647 0.353 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.647 0.353 0.000
I45.2 Bifascicular block
0.647 0.353 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.646 0.353 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.646 0.353 0.000
G93 Other disorders of brain
0.645 0.355 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.645 0.355 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.645 0.355 0.000
G47 Sleep disorders
0.645 0.355 0.000
J09-J18 Influenza and pneumonia
0.645 0.355 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.644 0.356 0.000
O91 Infections of breast associated with childbirth
0.644 0.356 0.000
O89 Complications of anaesthesia during the puerperium
0.644 0.356 0.000
O88 Obstetric embolism
0.644 0.356 0.000
O87 Venous complications in the puerperium
0.644 0.356 0.000
Y59 Other and unspecified vaccines and biological substances
0.644 0.356 0.000
Y58 Bacterial vaccines
0.644 0.356 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.644 0.356 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.644 0.356 0.000
Y48 Anaesthetics and therapeutic gases
0.644 0.356 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.644 0.356 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.643 0.357 0.000
G30-G32 Other degenerative diseases of the nervous system
0.643 0.357 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.642 0.358 0.000
Z94.6 Bone transplant status
0.642 0.358 0.000
Z94.5 Skin transplant status
0.642 0.358 0.000
Z94.3 Heart and lungs transplant status
0.642 0.358 0.000
Z94.2 Lung transplant status
0.642 0.358 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.642 0.358 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.641 0.358 0.000
J86.0 Pyothorax with fistula
0.641 0.359 0.000
O45 Premature separation of placenta [abruptio placentae]
0.641 0.359 0.000
O33 Maternal care for known or suspected disproportion
0.641 0.359 0.000
O31 Complications specific to multiple gestation
0.641 0.359 0.000
I51.5 Myocardial degeneration
0.641 0.359 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.641 0.359 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.641 0.359 0.000
I51.0 Cardiac septal defect, acquired
0.641 0.359 0.000
I51.4 Myocarditis, unspecified
0.640 0.360 0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]
0.640 0.360 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.640 0.360 0.000
C13 Malignant neoplasm of hypopharynx
0.640 0.360 0.000
C11 Malignant neoplasm of nasopharynx
0.640 0.360 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.640 0.360 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.640 0.360 0.000
C05 Malignant neoplasm of palate
0.640 0.360 0.000
C03 Malignant neoplasm of gum
0.640 0.360 0.000
C00 Malignant neoplasm of lip
0.640 0.360 0.000
Z64 Problems related to certain psychosocial circumstances
0.640 0.360 0.000
I78.8 Other diseases of capillaries
0.639 0.361 0.000
O90.1 Disruption of perineal obstetric wound
0.639 0.361 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.639 0.361 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.639 0.361 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.639 0.361 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.638 0.362 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.638 0.362 0.000
B65-B83 Helminthiases
0.637 0.363 0.000
Y49.2 Other and unspecified antidepressants
0.637 0.363 0.000
Z89.6 Acquired absence of leg above knee
0.636 0.363 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.636 0.364 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.635 0.365 0.000
Q60-Q64 Congenital malformations of the urinary system
0.634 0.365 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.634 0.366 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.634 0.366 0.000
G91 Hydrocephalus
0.634 0.366 0.000
C16 Malignant neoplasm of stomach
0.633 0.366 0.000
I31.8 Other specified diseases of pericardium
0.633 0.367 0.000
I31.2 Haemopericardium, not elsewhere classified
0.633 0.367 0.000
I31.0 Chronic adhesive pericarditis
0.633 0.367 0.000
B49 Unspecified mycosis
0.632 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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