TreeWAS – Variant ID: rs34626435

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.1 Left ventricular failure	0.000	0.889	0.111
I50 Heart failure	0.000	0.953	0.047
I50.0 Congestive heart failure	0.000	0.962	0.038
T43.0 Tricyclic and tetracyclic antidepressants	0.029	0.971	0.000
I50.9 Heart failure, unspecified	0.000	0.972	0.028
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.026	0.974	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.022	0.978	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.020	0.979	0.000
T43.6 Psychostimulants with abuse potential	0.020	0.980	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.020	0.980	0.000
T43.2 Other and unspecified antidepressants	0.020	0.980	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.020	0.980	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.019	0.981	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.019	0.981	0.000
T43.9 Psychotropic drug, unspecified	0.019	0.981	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.019	0.981	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.019	0.981	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.019	0.981	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.018	0.982	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.018	0.982	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.017	0.982	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.017	0.983	0.000
T36 Poisoning by systemic antibiotics	0.017	0.983	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.017	0.983	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.016	0.984	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.984	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.016	0.984	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.016	0.984	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.016	0.984	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.016	0.984	0.000
T45.5 Anticoagulants	0.016	0.984	0.000
T45.0 Antiallergic and antiemetic drugs	0.015	0.985	0.000
T46.1 Calcium-channel blockers	0.015	0.985	0.000
T38.1 Thyroid hormones and substitutes	0.015	0.985	0.000
T50.8 Diagnostic agents	0.015	0.985	0.000
T50.7 Analeptics and opioid receptor antagonists	0.015	0.985	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.015	0.985	0.000
T50.5 Appetite depressants	0.015	0.985	0.000
T50.4 Drugs affecting uric acid metabolism	0.015	0.985	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.015	0.985	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.015	0.985	0.000
T50.1 Loop [high-ceiling] diuretics	0.015	0.985	0.000
T50.0 Mineralocorticoids and their antagonists	0.015	0.985	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.015	0.985	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.015	0.985	0.000
T46.7 Peripheral vasodilators	0.015	0.985	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.015	0.985	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.015	0.985	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.015	0.985	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.014	0.986	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.014	0.986	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.014	0.986	0.000
T45.8 Other primarily systemic and haematological agents	0.014	0.986	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.014	0.986	0.000
T45.6 Fibrinolysis-affecting drugs	0.014	0.986	0.000
T45.4 Iron and its compounds	0.014	0.986	0.000
T45.3 Enzymes, not elsewhere classified	0.014	0.986	0.000
T45.2 Vitamins, not elsewhere classified	0.014	0.986	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.014	0.986	0.000
T42.0 Hydantoin derivatives	0.014	0.986	0.000
T36.0 Penicillins	0.013	0.987	0.000
T38.9 Other and unspecified hormone antagonists	0.013	0.987	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.013	0.987	0.000
T38.7 Androgens and anabolic congeners	0.013	0.987	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.013	0.987	0.000
T38.5 Other oestrogens and progestogens	0.013	0.987	0.000
T38.4 Oral contraceptives	0.013	0.987	0.000
T38.2 Antithyroid drugs	0.013	0.987	0.000
T38.0 Glucocorticoids and synthetic analogues	0.013	0.987	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.013	0.987	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.013	0.987	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.013	0.987	0.000
T47.7 Emetics	0.013	0.987	0.000
T47.6 Antidiarrhoeal drugs	0.013	0.987	0.000
T47.5 Digestants	0.013	0.987	0.000
T47.4 Other laxatives	0.013	0.987	0.000
T47.3 Saline and osmotic laxatives	0.013	0.987	0.000
T47.2 Stimulant laxatives	0.013	0.987	0.000
T47.0 Histamine H(2)-receptor antagonists	0.013	0.987	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.012	0.988	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.012	0.988	0.000
T42.3 Barbiturates	0.012	0.988	0.000
T42.2 Succinimides and oxazolidinediones	0.012	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.012	0.988	0.000
T36.8 Other systemic antibiotics	0.012	0.988	0.000
T36.7 Antifungal antibiotics, systemically used	0.012	0.988	0.000
T36.6 Rifamycins	0.012	0.988	0.000
T36.5 Aminoglycosides	0.012	0.988	0.000
T36.4 Tetracyclines	0.012	0.988	0.000
T36.3 Macrolides	0.012	0.988	0.000
T36.2 Chloramphenicol group	0.012	0.988	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.012	0.988	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.012	0.988	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.012	0.988	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.012	0.988	0.000
T37.5 Antiviral drugs	0.012	0.988	0.000
T37.4 Anthelminthics	0.012	0.988	0.000
T37.3 Other antiprotozoal drugs	0.012	0.988	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.012	0.988	0.000
T37.1 Antimycobacterial drugs	0.012	0.988	0.000
T37.0 Sulphonamides	0.012	0.988	0.000
T41.5 Therapeutic gases	0.012	0.988	0.000
T41.4 Anaesthetic, unspecified	0.012	0.988	0.000
T41.3 Local anaesthetics	0.012	0.988	0.000
T41.2 Other and unspecified general anaesthetics	0.012	0.988	0.000
T41.1 Intravenous anaesthetics	0.012	0.988	0.000
T41.0 Inhaled anaesthetics	0.012	0.988	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.012	0.988	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.012	0.988	0.000
T48.5 Anti-common-cold drugs	0.012	0.988	0.000
T48.4 Expectorants	0.012	0.988	0.000
T48.3 Antitussives	0.012	0.988	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.012	0.988	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.012	0.988	0.000
T48.0 Oxytocic drugs	0.012	0.988	0.000
T49.9 Topical agent, unspecified	0.012	0.988	0.000
T49.8 Other topical agents	0.012	0.988	0.000
T49.7 Dental drugs, topically applied	0.012	0.988	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.012	0.988	0.000
T49.5 Ophthalmological drugs and preparations	0.012	0.988	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.012	0.988	0.000
T49.3 Emollients, demulcents and protectants	0.012	0.988	0.000
T49.2 Local astringents and local detergents	0.012	0.988	0.000
T49.1 Antipruritics	0.012	0.988	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.012	0.988	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.012	0.988	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.012	0.988	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.012	0.988	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.012	0.988	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.012	0.988	0.000
T44.0 Anticholinesterase agents	0.012	0.988	0.000
T42.1 Iminostilbenes	0.011	0.989	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.011	0.989	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.011	0.989	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.011	0.989	0.000
C67.9 Bladder, unspecified	0.000	0.990	0.010
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.009	0.991	0.000
T42.4 Benzodiazepines	0.009	0.991	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.008	0.992	0.000
T39.4 Antirheumatics, not elsewhere classified	0.008	0.992	0.000
T39.2 Pyrazolone derivatives	0.008	0.992	0.000
T39.0 Salicylates	0.008	0.992	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.993	0.007
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.993	0.007
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.007	0.993	0.000
T40.8 Lysergide [LSD]	0.007	0.993	0.000
T40.7 Cannabis (derivatives)	0.007	0.993	0.000
T40.5 Cocaine	0.007	0.993	0.000
T40.3 Methadone	0.007	0.993	0.000
T40.1 Heroin	0.007	0.993	0.000
T40.0 Opium	0.007	0.993	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
C67 Malignant neoplasm of bladder	0.000	0.994	0.006
T40.6 Other and unspecified narcotics	0.006	0.994	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.994	0.006
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.994	0.006
T40.4 Other synthetic narcotics	0.006	0.994	0.000
C67.4 Posterior wall of bladder	0.000	0.994	0.006
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
C67.6 Ureteric orifice	0.000	0.995	0.005
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.995	0.005
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.995	0.005
C67.2 Lateral wall of bladder	0.000	0.995	0.005
C67.5 Bladder neck	0.000	0.995	0.005
C67.7 Urachus	0.000	0.995	0.005
C67.0 Trigone of bladder	0.000	0.995	0.005
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.995	0.005
I42.0 Dilated cardiomyopathy	0.000	0.995	0.005
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.995	0.004
C67.8 Overlapping lesion of bladder	0.000	0.995	0.004
T39.1 4-Aminophenol derivatives	0.005	0.995	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.996	0.004
I42 Cardiomyopathy	0.000	0.996	0.004
C67.1 Dome of bladder	0.000	0.996	0.004
E87.7 Fluid overload	0.004	0.996	0.000
S61.1 Open wound of finger(s) with damage to nail	0.004	0.996	0.000
H54.9 Unspecified visual impairment (binocular)	0.004	0.996	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.996	0.004
T40.2 Other opioids	0.004	0.996	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.996	0.004
I42.8 Other cardiomyopathies	0.000	0.996	0.004
C67.3 Anterior wall of bladder	0.000	0.996	0.003
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.996	0.004
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.997	0.003
I42.5 Other restrictive cardiomyopathy	0.000	0.997	0.003
I42.4 Endocardial fibroelastosis	0.000	0.997	0.003
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.997	0.003
H54.4 Blindness, one eye	0.003	0.997	0.000
W22.9 Unspecified place	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
H54.6 Unqualified visual loss, one eye	0.003	0.997	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.997	0.003
H54.1 Blindness, one eye, low vision, other eye	0.003	0.997	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.003	0.997	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.997	0.003
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.997	0.003
M48.06 Spinal stenosis (Lumbar region)	0.000	0.997	0.003
H54.5 Low vision, one eye	0.002	0.997	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.997	0.000
H54.2 Low vision, both eyes	0.002	0.997	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.998	0.002
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.001	0.998	0.001
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
B00.4 Herpesviral encephalitis	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
Z91.5 Personal history of self-harm	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.002	0.998	0.000
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
W22 Striking against or struck by other objects	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
H54.7 Unspecified visual loss	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
S41.0 Open wound of shoulder	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
C32.1 Supraglottis	0.002	0.998	0.000
W22.2 School, other institution and public administrative area	0.002	0.998	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.002	0.998	0.000
D09.0 Bladder	0.000	0.998	0.002
I84.4 External haemorrhoids with other complications	0.000	0.998	0.002
K76.9 Liver disease, unspecified	0.000	0.998	0.002
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
Z50.5 Speech therapy	0.000	0.998	0.002
T17.5 Foreign body in bronchus	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
K82.8 Other specified diseases of gallbladder	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
B00.8 Other forms of herpesviral infection	0.002	0.998	0.000
B00.7 Disseminated herpesviral disease	0.002	0.998	0.000
B00.3 Herpesviral meningitis	0.002	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.002	0.998	0.000
B00.0 Eczema herpeticum	0.002	0.998	0.000
W22.8 Other specified place	0.002	0.998	0.000
W22.6 Industrial and construction area	0.002	0.998	0.000
W22.4 Street and highway	0.002	0.998	0.000
W22.0 Home	0.002	0.998	0.000
W22.7 Farm	0.002	0.998	0.000
W22.5 Trade and service area	0.002	0.998	0.000
W22.1 Residential institution	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
T13 Other injuries of lower limb, level unspecified	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
W22.3 Sports and athletics area	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
T17 Foreign body in respiratory tract	0.002	0.998	0.000
I49.1 Atrial premature depolarisation	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.000	0.998	0.002
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
M81.94 Osteoporosis, unspecified (Hand)	0.001	0.998	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.001	0.998	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.001	0.998	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.001	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.001	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
T09 Other injuries of spine and trunk, level unspecified	0.002	0.998	0.000
G00.1 Pneumococcal meningitis	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.001	0.998	0.000
T18 Foreign body in alimentary tract	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.998	0.000
S11.9 Open wound of neck, part unspecified	0.001	0.998	0.000
S52.1 Fracture of upper end of radius	0.000	0.998	0.001
T17.2 Foreign body in pharynx	0.002	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
W22.09 Striking against or struck by other objects; Home; During unspecified activity	0.001	0.998	0.000
W22.03 Striking against or struck by other objects; Home; While engaged in other types of work	0.001	0.998	0.000
W22.41 Striking against or struck by other objects; Street and highway;While engaged in leisure activity	0.001	0.998	0.000
W22.62 Striking against or struck by other objects; Industrial and construction area ;While working for income	0.001	0.998	0.000
W22.88 Striking against or struck by other objects; Other specified places ;While engaged in other specified activities	0.001	0.998	0.000
B00.5 Herpesviral ocular disease	0.001	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.002
H33.3 Retinal breaks without detachment	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.998	0.002
B35.3 Tinea pedis	0.002	0.998	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.001	0.998	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.001	0.998	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.001	0.998	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.001	0.998	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.001	0.998	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.001	0.998	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.001	0.998	0.000
T13.1 Open wound of lower limb, level unspecified	0.001	0.998	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.001	0.998	0.000
T18.0 Foreign body in mouth	0.001	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.001	0.998	0.000
S11 Open wound of neck	0.001	0.998	0.000
C91.0 Acute lymphoblastic leukaemia	0.001	0.998	0.000
T09.0 Superficial injury of trunk, level unspecified	0.001	0.998	0.000
Z60.2 Living alone	0.000	0.998	0.002
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.001	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.001	0.998	0.000
S19 Other and unspecified injuries of neck	0.001	0.998	0.000
T11 Other injuries of upper limb, level unspecified	0.001	0.998	0.000
C18.2 Ascending colon	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
M84.9 Disorder of continuity of bone, unspecified	0.001	0.998	0.000
M84.8 Other disorders of continuity of bone	0.001	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.998	0.000
T17.4 Foreign body in trachea	0.001	0.998	0.000
T17.3 Foreign body in larynx	0.001	0.998	0.000
T17.1 Foreign body in nostril	0.001	0.998	0.000
T17.0 Foreign body in nasal sinus	0.001	0.998	0.000
I49 Other cardiac arrhythmias	0.000	0.998	0.002
T16 Foreign body in ear	0.001	0.998	0.000
S10-S19 Injuries to the neck	0.001	0.998	0.000
S19.9 Unspecified injury of neck	0.001	0.998	0.000
S41.1 Open wound of upper arm	0.001	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.998	0.001
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.999	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.999	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.999	0.001
T11.1 Open wound of upper limb, level unspecified	0.001	0.999	0.000
Y85 Sequelae of transport accidents	0.001	0.999	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.999	0.001
C32 Malignant neoplasm of larynx	0.001	0.999	0.000
G00.9 Bacterial meningitis, unspecified	0.001	0.999	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.001	0.999	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.001	0.999	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.001	0.999	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.001	0.999	0.000
T09.3 Injury of spinal cord, level unspecified	0.001	0.999	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.001	0.999	0.000
T09.1 Open wound of trunk, level unspecified	0.001	0.999	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.001	0.999	0.000
T18.5 Foreign body in anus and rectum	0.001	0.999	0.000
T18.4 Foreign body in colon	0.001	0.999	0.000
T18.3 Foreign body in small intestine	0.001	0.999	0.000
T18.2 Foreign body in stomach	0.001	0.999	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.999	0.001
K10.8 Other specified diseases of jaws	0.001	0.999	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.001	0.999	0.000
W10.8 Other specified place	0.001	0.999	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.001	0.999	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.001	0.999	0.000
T12 Fracture of lower limb, level unspecified	0.001	0.999	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.001	0.999	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.001	0.999	0.000
T10 Fracture of upper limb, level unspecified	0.001	0.999	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.001	0.999	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.001	0.999	0.000
T08 Fracture of spine, level unspecified	0.001	0.999	0.000
T19 Foreign body in genito-urinary tract	0.001	0.999	0.000
T15 Foreign body on external eye	0.001	0.999	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.999	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.999	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.999	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S32.30 Fracture of ilium (closed)	0.001	0.999	0.000
S52.11 Fracture of upper end of radius (open)	0.000	0.999	0.001
F40.2 Specific (isolated) phobias	0.001	0.999	0.000
S19.8 Other specified injuries of neck	0.001	0.999	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.001	0.999	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.001	0.999	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.999	0.000
M22.4 Chondromalacia patellae	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.999	0.000
M81.8 Other osteoporosis	0.001	0.999	0.000
M81.6 Localised osteoporosis [Lequesne]	0.001	0.999	0.000
M81.5 Idiopathic osteoporosis	0.001	0.999	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.001	0.999	0.000
M81.1 Postoophorectomy osteoporosis	0.001	0.999	0.000
M81.0 Postmenopausal osteoporosis	0.001	0.999	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
T90.9 Sequelae of unspecified injury of head	0.001	0.999	0.000
R09.2 Respiratory arrest	0.000	0.999	0.001
S14.6 Injury of other and unspecified nerves of neck	0.001	0.999	0.000
S14.5 Injury of cervical sympathetic nerves	0.001	0.999	0.000
S14.4 Injury of peripheral nerves of neck	0.001	0.999	0.000
S14.3 Injury of brachial plexus	0.001	0.999	0.000
S14.2 Injury of nerve root of cervical spine	0.001	0.999	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.001	0.999	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.999	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.001	0.999	0.000
W44.0 Home	0.001	0.999	0.000
M80-M85 Disorders of bone density and structure	0.001	0.999	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.999	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations