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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34670419
log Bayes Factor = 1.0504
Chromosome 7   position 99,130,834  (GRCh37) Explore rs34670419 on Ensembl!
Variant rs34670419 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.127 0.873
I51.7 Cardiomegaly
0.000 0.144 0.856
I10-I15 Hypertensive diseases
0.000 0.152 0.848
I51 Complications and ill-defined descriptions of heart disease
0.000 0.156 0.844
I30-I52 Other forms of heart disease
0.000 0.159 0.841
Chapter IX Diseases of the circulatory system
0.000 0.167 0.833
I44 Atrioventricular and left bundle-branch block
0.000 0.246 0.754
I05-I09 Chronic rheumatic heart diseases
0.000 0.250 0.750
I49 Other cardiac arrhythmias
0.000 0.277 0.723
I44.0 Atrioventricular block, first degree
0.000 0.288 0.712
I50 Heart failure
0.000 0.292 0.708
I49.9 Cardiac arrhythmia, unspecified
0.000 0.299 0.701
I42 Cardiomyopathy
0.000 0.303 0.697
I08 Multiple valve diseases
0.000 0.306 0.694
I33 Acute and subacute endocarditis
0.000 0.324 0.676
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.349 0.651
I44.1 Atrioventricular block, second degree
0.000 0.362 0.638
I60-I69 Cerebrovascular diseases
0.000 0.363 0.637
I50.1 Left ventricular failure
0.000 0.372 0.628
I38 Endocarditis, valve unspecified
0.000 0.374 0.626
I11 Hypertensive heart disease
0.000 0.377 0.623
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.385 0.615
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.391 0.608
I15 Secondary hypertension
0.000 0.392 0.608
I13 Hypertensive heart and renal disease
0.000 0.392 0.608
I51.6 Cardiovascular disease, unspecified
0.000 0.395 0.605
I51.5 Myocardial degeneration
0.000 0.395 0.605
I51.4 Myocarditis, unspecified
0.000 0.395 0.605
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.395 0.605
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.395 0.605
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.395 0.605
I51.0 Cardiac septal defect, acquired
0.000 0.395 0.605
I52 Other heart disorders in diseases classified elsewhere
0.000 0.397 0.603
I48 Atrial fibrillation and flutter
0.000 0.397 0.603
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.397 0.603
I41 Myocarditis in diseases classified elsewhere
0.000 0.397 0.603
I40 Acute myocarditis
0.000 0.397 0.603
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.397 0.603
I32 Pericarditis in diseases classified elsewhere
0.000 0.397 0.603
I00-I02 Acute rheumatic fever
0.000 0.403 0.597
I36 Nonrheumatic tricuspid valve disorders
0.000 0.407 0.593
I50.0 Congestive heart failure
0.000 0.408 0.592
I30 Acute pericarditis
0.000 0.410 0.590
I67 Other cerebrovascular diseases
0.000 0.419 0.581
I07 Rheumatic tricuspid valve diseases
0.000 0.422 0.578
I42.2 Other hypertrophic cardiomyopathy
0.000 0.429 0.571
I37 Pulmonary valve disorders
0.000 0.432 0.568
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.434 0.566
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.435 0.564
I33.0 Acute and subacute infective endocarditis
0.000 0.441 0.559
I34 Nonrheumatic mitral valve disorders
0.000 0.448 0.552
I51.9 Heart disease, unspecified
0.000 0.449 0.551
I44.7 Left bundle-branch block, unspecified
0.000 0.450 0.550
I67.9 Cerebrovascular disease, unspecified
0.000 0.450 0.550
I12 Hypertensive renal disease
0.000 0.452 0.548
I44.5 Left posterior fascicular block
0.000 0.459 0.541
I44.4 Left anterior fascicular block
0.000 0.459 0.541
I09 Other rheumatic heart diseases
0.000 0.462 0.537
I06 Rheumatic aortic valve diseases
0.000 0.462 0.537
I44.6 Other and unspecified fascicular block
0.000 0.464 0.536
I20-I25 Ischaemic heart diseases
0.000 0.465 0.535
I49.5 Sick sinus syndrome
0.000 0.468 0.532
I35 Nonrheumatic aortic valve disorders
0.000 0.471 0.529
I49.8 Other specified cardiac arrhythmias
0.000 0.474 0.526
I49.2 Junctional premature depolarisation
0.000 0.481 0.519
I31 Other diseases of pericardium
0.000 0.491 0.509
I45 Other conduction disorders
0.000 0.494 0.506
I27 Other pulmonary heart diseases
0.000 0.494 0.506
I08.8 Other multiple valve diseases
0.000 0.496 0.504
I42.8 Other cardiomyopathies
0.000 0.500 0.500
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.500 0.500
I42.6 Alcoholic cardiomyopathy
0.000 0.500 0.500
I42.5 Other restrictive cardiomyopathy
0.000 0.500 0.500
I42.4 Endocardial fibroelastosis
0.000 0.500 0.500
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.500 0.500
I08.9 Multiple valve disease, unspecified
0.000 0.503 0.497
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.503 0.497
I63 Cerebral infarction
0.000 0.503 0.497
I20 Angina pectoris
0.000 0.508 0.492
I46 Cardiac arrest
0.000 0.511 0.488
I33.9 Acute endocarditis, unspecified
0.000 0.515 0.485
I51.8 Other ill-defined heart diseases
0.000 0.521 0.479
I42.0 Dilated cardiomyopathy
0.000 0.521 0.479
I42.9 Cardiomyopathy, unspecified
0.000 0.522 0.478
I05 Rheumatic mitral valve diseases
0.000 0.529 0.471
I67.1 Cerebral aneurysm, nonruptured
0.000 0.529 0.471
I35.0 Aortic (valve) stenosis
0.000 0.533 0.467
I44.3 Other and unspecified atrioventricular block
0.000 0.537 0.462
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.539 0.461
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.543 0.457
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.543 0.457
I07.1 Tricuspid insufficiency
0.000 0.545 0.455
I63.9 Cerebral infarction, unspecified
0.000 0.548 0.452
I20.9 Angina pectoris, unspecified
0.000 0.549 0.451
I49.3 Ventricular premature depolarisation
0.000 0.549 0.450
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.553 0.447
I49.1 Atrial premature depolarisation
0.000 0.555 0.445
I49.0 Ventricular fibrillation and flutter
0.000 0.556 0.444
I28 Other diseases of pulmonary vessels
0.000 0.559 0.441
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.560 0.440
I34.0 Mitral (valve) insufficiency
0.000 0.561 0.439
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.564 0.436
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.564 0.436
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.564 0.436
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.564 0.436
I15.9 Seconday hypertension, unspecified
0.000 0.564 0.436
I15.8 Other secondary hypertension
0.000 0.564 0.436
I15.2 Hypertension secondary to endocrine disorders
0.000 0.564 0.436
I15.1 Hypertension secondary to other renal disorders
0.000 0.564 0.436
I15.0 Renovascular hypertension
0.000 0.564 0.436
I20.8 Other forms of angina pectoris
0.000 0.566 0.434
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.568 0.432
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.568 0.432
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.568 0.432
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.568 0.432
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.568 0.432
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.568 0.432
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.568 0.432
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.568 0.432
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.568 0.432
I40.9 Acute myocarditis, unspecified
0.000 0.568 0.432
I40.8 Other acute myocarditis
0.000 0.568 0.432
I40.1 Isolated myocarditis
0.000 0.568 0.432
I40.0 Infective myocarditis
0.000 0.568 0.432
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.568 0.432
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.568 0.432
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.568 0.432
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.568 0.432
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.568 0.432
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.568 0.432
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.568 0.432
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.568 0.432
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.568 0.432
I48.4 Atypical atrial flutter
0.000 0.568 0.432
I48.3 Typical atrial flutter
0.000 0.568 0.432
I48.2 Chronic atrial fibrillation
0.000 0.568 0.432
I48.1 Persistent atrial fibrillation
0.000 0.568 0.432
I48.0 Paroxysmal atrial fibrillation
0.000 0.568 0.432
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.568 0.432
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.568 0.432
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.568 0.432
I02 Rheumatic chorea
0.000 0.572 0.428
I01 Rheumatic fever with heart involvement
0.000 0.572 0.428
I00 Rheumatic fever without mention of heart involvement
0.000 0.572 0.428
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.575 0.425
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.575 0.425
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.575 0.425
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.575 0.425
I12.9 Hypertensive renal disease without renal failure
0.000 0.575 0.425
I30.8 Other forms of acute pericarditis
0.000 0.577 0.423
I30.1 Infective pericarditis
0.000 0.577 0.423
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.577 0.423
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.583 0.417
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.583 0.417
I67.5 Moyamoya disease
0.000 0.583 0.417
I67.4 Hypertensive encephalopathy
0.000 0.583 0.417
I67.3 Progressive vascular leukoencephalopathy
0.000 0.583 0.417
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.583 0.417
I21 Acute myocardial infarction
0.000 0.583 0.417
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.584 0.415
I07.9 Tricuspid valve disease, unspecified
0.000 0.585 0.414
I07.8 Other tricuspid valve diseases
0.000 0.585 0.414
I07.2 Tricuspid stenosis with insufficiency
0.000 0.585 0.414
I07.0 Tricuspid stenosis
0.000 0.585 0.414
I27.2 Other secondary pulmonary hypertension
0.000 0.586 0.414
I30.9 Acute pericarditis, unspecified
0.000 0.590 0.410
I35.8 Other aortic valve disorders
0.000 0.591 0.408
I47 Paroxysmal tachycardia
0.000 0.592 0.408
I37.9 Pulmonary valve disorder, unspecified
0.000 0.592 0.407
I37.8 Other pulmonary valve disorders
0.000 0.592 0.407
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.592 0.407
I37.0 Pulmonary valve stenosis
0.000 0.592 0.407
I21.4 Acute subendocardial myocardial infarction
0.000 0.594 0.406
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.601 0.398
I62 Other nontraumatic intracranial haemorrhage
0.000 0.602 0.397
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.603 0.397
I27.0 Primary pulmonary hypertension
0.000 0.603 0.397
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.604 0.396
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.604 0.396
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.604 0.396
I61 Intracerebral haemorrhage
0.000 0.604 0.396
I49.4 Other and unspecified premature depolarisation
0.000 0.609 0.390
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.614 0.385
I06.8 Other rheumatic aortic valve diseases
0.000 0.614 0.385
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.614 0.385
I06.1 Rheumatic aortic insufficiency
0.000 0.614 0.385
I06.0 Rheumatic aortic stenosis
0.000 0.614 0.385
I09.9 Rheumatic heart disease, unspecified
0.000 0.614 0.385
I09.8 Other specified rheumatic heart diseases
0.000 0.614 0.385
I09.2 Chronic rheumatic pericarditis
0.000 0.614 0.385
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.614 0.385
I09.0 Rheumatic myocarditis
0.000 0.614 0.385
I23 Certain current complications following acute myocardial infarction
0.000 0.616 0.384
I63.8 Other cerebral infarction
0.000 0.618 0.382
I45.1 Other and unspecified right bundle-branch block
0.000 0.625 0.375
I37.1 Pulmonary valve insufficiency
0.000 0.627 0.373
I31.3 Pericardial effusion (noninflammatory)
0.000 0.634 0.366
I26 Pulmonary embolism
0.000 0.635 0.365
I31.8 Other specified diseases of pericardium
0.000 0.635 0.365
I31.2 Haemopericardium, not elsewhere classified
0.000 0.635 0.365
I31.1 Chronic constrictive pericarditis
0.000 0.635 0.365
I31.0 Chronic adhesive pericarditis
0.000 0.635 0.365
I45.4 Nonspecific intraventricular block
0.000 0.637 0.363
I45.3 Trifascicular block
0.000 0.637 0.363
I45.0 Right fascicular block
0.000 0.637 0.363
I45.9 Conduction disorder, unspecified
0.000 0.637 0.363
I27.8 Other specified pulmonary heart diseases
0.000 0.637 0.363
I27.1 Kyphoscoliotic heart disease
0.000 0.637 0.363
I45.6 Preexcitation syndrome
0.000 0.638 0.361
I67.8 Other specified cerebrovascular diseases
0.000 0.641 0.359
I99 Other and unspecified disorders of circulatory system
0.000 0.643 0.357
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.644 0.356
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.644 0.356
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.644 0.356
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.644 0.356
I67.2 Cerebral atherosclerosis
0.000 0.644 0.356
I24 Other acute ischaemic heart diseases
0.000 0.644 0.356
I46.1 Sudden cardiac death, so described
0.000 0.650 0.350
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.650 0.350
I83 Varicose veins of lower extremities
0.000 0.652 0.348
I27.9 Pulmonary heart disease, unspecified
0.000 0.655 0.345
I45.2 Bifascicular block
0.000 0.655 0.344
I05.8 Other mitral valve diseases
0.000 0.662 0.338
I05.1 Rheumatic mitral insufficiency
0.000 0.662 0.338
I05.0 Mitral stenosis
0.000 0.662 0.338
I45.8 Other specified conduction disorders
0.000 0.663 0.337
I44.2 Atrioventricular block, complete
0.000 0.671 0.328
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.672 0.327
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.672 0.327
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.672 0.327
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.672 0.327
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.672 0.327
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.672 0.327
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.672 0.327
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.672 0.327
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.672 0.327
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.672 0.327
I68.0 Cerebral amyloid angiopathy
0.000 0.672 0.327
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.673 0.327
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.675 0.325
I46.9 Cardiac arrest, unspecified
0.000 0.679 0.321
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.679 0.320
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.682 0.318
I69 Sequelae of cerebrovascular disease
0.000 0.682 0.318
I05.2 Mitral stenosis with insufficiency
0.000 0.684 0.316
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.684 0.316
I28.8 Other specified diseases of pulmonary vessels
0.000 0.684 0.316
I28.1 Aneurysm of pulmonary artery
0.000 0.684 0.316
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.684 0.316
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.684 0.315
I20.0 Unstable angina
0.000 0.688 0.312
I45.5 Other specified heart block
0.000 0.690 0.310
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.691 0.309
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.693 0.307
I01.8 Other acute rheumatic heart disease
0.000 0.693 0.307
I01.2 Acute rheumatic myocarditis
0.000 0.693 0.307
I01.1 Acute rheumatic endocarditis
0.000 0.693 0.307
I01.0 Acute rheumatic pericarditis
0.000 0.693 0.307
I02.9 Rheumatic chorea without heart involvement
0.000 0.693 0.307
I02.0 Rheumatic chorea with heart involvement
0.000 0.693 0.307
I86 Varicose veins of other sites
0.000 0.696 0.304
I05.9 Mitral valve disease, unspecified
0.000 0.701 0.299
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.701 0.299
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.701 0.299
I20.1 Angina pectoris with documented spasm
0.000 0.702 0.298
I35.1 Aortic (valve) insufficiency
0.000 0.704 0.296
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.705 0.295
I50.9 Heart failure, unspecified
0.000 0.706 0.294
I87 Other disorders of veins
0.000 0.706 0.294
I47.0 Reentry ventricular arrhythmia
0.000 0.707 0.293
I81 Portal vein thrombosis
0.000 0.709 0.291
I60 Subarachnoid haemorrhage
0.000 0.710 0.289
I47.2 Ventricular tachycardia
0.000 0.711 0.289
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.714 0.286
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.714 0.286
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.714 0.286
I65.1 Occlusion and stenosis of basilar artery
0.000 0.714 0.286
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.714 0.286
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.714 0.286
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.715 0.285
I62.1 Nontraumatic extradural haemorrhage
0.000 0.715 0.285
I61.8 Other intracerebral haemorrhage
0.000 0.716 0.284
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.716 0.284
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.716 0.284
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.716 0.284
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.716 0.284
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.716 0.284
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.716 0.284
I46.0 Cardiac arrest with successful resuscitation
0.000 0.720 0.280
I12.0 Hypertensive renal disease with renal failure
0.000 0.721 0.279
I82 Other venous embolism and thrombosis
0.000 0.722 0.277
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.722 0.277
I23.8 Other current complications following acute myocardial infarction
0.000 0.725 0.275
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.725 0.275
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.725 0.275
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.725 0.275
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.725 0.275
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.725 0.275
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.725 0.275
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.725 0.275
I31.9 Disease of pericardium, unspecified
0.000 0.731 0.269
I88 Nonspecific lymphadenitis
0.000 0.732 0.268
I34.1 Mitral (valve) prolapse
0.000 0.733 0.267
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.736 0.263
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.738 0.262
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.739 0.261
I22 Subsequent myocardial infarction
0.000 0.739 0.260
I08.0 Disorders of both mitral and aortic valves
0.001 0.742 0.257
I89.0 Lymphoedema, not elsewhere classified
0.000 0.743 0.257
I24.1 Dressler's syndrome
0.000 0.744 0.255
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.750 0.250
I86.1 Scrotal varices
0.000 0.758 0.242
I89.1 Lymphangitis
0.000 0.759 0.241
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.761 0.239
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.767 0.233
I87.1 Compression of vein
0.000 0.770 0.230
I35.9 Aortic valve disorder, unspecified
0.001 0.771 0.228
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.771 0.228
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.772 0.228
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.772 0.228
I65.2 Occlusion and stenosis of carotid artery
0.000 0.772 0.227
I87.8 Other specified disorders of veins
0.000 0.772 0.227
I82.8 Embolism and thrombosis of other specified veins
0.000 0.773 0.227
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.774 0.226
I21.9 Acute myocardial infarction, unspecified
0.000 0.777 0.223
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.778 0.222
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.778 0.222
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.780 0.220
I86.8 Varicose veins of other specified sites
0.000 0.782 0.218
I86.3 Vulval varices
0.000 0.782 0.218
I86.2 Pelvic varices
0.000 0.782 0.218
I86.0 Sublingual varices
0.000 0.782 0.218
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.787 0.213
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.788 0.212
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.788 0.212
I97.0 Postcardiotomy syndrome
0.000 0.788 0.212
I87.9 Disorder of vein, unspecified
0.000 0.789 0.211
I87.0 Postphlebitic syndrome
0.000 0.789 0.211
I86.4 Gastric varices
0.000 0.790 0.210
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.791 0.209
I60.8 Other subarachnoid haemorrhage
0.000 0.792 0.207
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.792 0.207
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.792 0.207
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.792 0.207
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.792 0.207
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.792 0.207
I97.1 Other functional disturbances following cardiac surgery
0.000 0.793 0.207
I85 Oesophageal varices
0.000 0.794 0.206
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.799 0.201
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.799 0.201
I82.3 Embolism and thrombosis of renal vein
0.000 0.801 0.199
I82.2 Embolism and thrombosis of vena cava
0.000 0.801 0.199
I82.1 Thrombophlebitis migrans
0.000 0.801 0.199
I82.0 Budd-Chiari syndrome
0.000 0.801 0.199
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.802 0.197
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.806 0.193
I88.8 Other nonspecific lymphadenitis
0.000 0.807 0.192
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.807 0.192
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.807 0.192
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.813 0.187
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.813 0.187
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.813 0.187
I98.0 Cardiovascular syphilis
0.000 0.813 0.187
I95 Hypotension
0.000 0.813 0.187
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.813 0.187
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.814 0.186
I80 Phlebitis and thrombophlebitis
0.000 0.817 0.183
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.824 0.175
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.825 0.174
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.826 0.173
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.826 0.173
I22.8 Subsequent myocardial infarction of other sites
0.000 0.831 0.169
I69.3 Sequelae of cerebral infarction
0.000 0.845 0.155
I95.2 Hypotension due to drugs
0.000 0.845 0.155
I82.9 Embolism and thrombosis of unspecified vein
0.001 0.856 0.144
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.856 0.144
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.858 0.142
I60.9 Subarachnoid haemorrhage, unspecified
0.001 0.861 0.139
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.862 0.138
I95.0 Idiopathic hypotension
0.000 0.866 0.134
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.867 0.132
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.868 0.132
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.871 0.129
I85.0 Oesophageal varices with bleeding
0.000 0.871 0.129
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.874 0.126
I95.8 Other hypotension
0.000 0.882 0.118
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.883 0.117
I24.8 Other forms of acute ischaemic heart disease
0.001 0.891 0.109
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.895 0.105
I85.9 Oesophageal varices without bleeding
0.000 0.898 0.102
I95.1 Orthostatic hypotension
0.000 0.910 0.090
I25 Chronic ischaemic heart disease
0.000 0.910 0.090
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.916 0.084
K58.9 Irritable bowel syndrome without diarrhoea
0.000 0.924 0.076
I25.3 Aneurysm of heart
0.000 0.931 0.069
I25.6 Silent myocardial ischaemia
0.000 0.935 0.065
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.935 0.065
I95.9 Hypotension, unspecified
0.000 0.937 0.063
I47.1 Supraventricular tachycardia
0.001 0.941 0.059
I25.4 Coronary artery aneurysm
0.000 0.941 0.059
I70-I79 Diseases of arteries, arterioles and capillaries
0.001 0.947 0.052
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.948 0.052
I84 Haemorrhoids
0.000 0.952 0.048
I84.2 Internal haemorrhoids without complication
0.000 0.956 0.044
K22.1 Ulcer of oesophagus
0.000 0.956 0.044
I70 Atherosclerosis
0.001 0.961 0.038
I25.5 Ischaemic cardiomyopathy
0.000 0.961 0.038
K26 Duodenal ulcer
0.000 0.961 0.039
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.963 0.036
I84.4 External haemorrhoids with other complications
0.000 0.964 0.036
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.965 0.035
I78 Diseases of capillaries
0.001 0.965 0.034
K26.7 Chronic without haemorrhage or perforation
0.000 0.966 0.034
I72 Other aneurysm
0.001 0.967 0.032
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.968 0.032
K58 Irritable bowel syndrome
0.000 0.970 0.030
K22 Other diseases of oesophagus
0.000 0.970 0.030
I84.1 Internal haemorrhoids with other complications
0.000 0.970 0.030
K26.4 Chronic or unspecified with haemorrhage
0.000 0.971 0.029
K22.9 Disease of oesophagus, unspecified
0.000 0.971 0.029
I70.2 Atherosclerosis of arteries of the extremities
0.001 0.971 0.028
I84.0 Internal thrombosed haemorrhoids
0.000 0.972 0.028
I70.9 Generalised and unspecified atherosclerosis
0.001 0.972 0.027
I70.8 Atherosclerosis of other arteries
0.001 0.972 0.027
I70.1 Atherosclerosis of renal artery
0.001 0.972 0.027
I70.0 Atherosclerosis of aorta
0.001 0.972 0.027
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.972 0.028
K26.2 Acute with both haemorrhage and perforation
0.000 0.972 0.028
K26.1 Acute with perforation
0.000 0.972 0.028
K26.0 Acute with haemorrhage
0.000 0.972 0.028
I25.2 Old myocardial infarction
0.000 0.972 0.028
I72.4 Aneurysm of artery of lower extremity
0.001 0.973 0.027
I74 Arterial embolism and thrombosis
0.001 0.973 0.026
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.973 0.026
I79.1 Aortitis in diseases classified elsewhere
0.001 0.973 0.026
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.001 0.973 0.026
I84.3 External thrombosed haemorrhoids
0.000 0.973 0.027
I78.1 Naevus, nonneoplastic
0.000 0.974 0.026
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.974 0.026
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.974 0.025
I78.9 Disease of capillaries, unspecified
0.001 0.975 0.024
K26.5 Chronic or unspecified with perforation
0.000 0.975 0.025
I84.9 Unspecified haemorrhoids without complication
0.000 0.975 0.025
I84.5 External haemorrhoids without complication
0.000 0.976 0.024
K25 Gastric ulcer
0.000 0.976 0.024
I72.9 Aneurysm of unspecified site
0.001 0.976 0.023
I72.6 Aneurysm and dissection of vertebral artery
0.001 0.976 0.023
I72.5 Aneurysm and dissection of other precerebral arteries
0.001 0.976 0.023
I72.2 Aneurysm of renal artery
0.001 0.976 0.023
I72.1 Aneurysm of artery of upper extremity
0.001 0.976 0.023
H35.3 Degeneration of macula and posterior pole
0.000 0.976 0.024
H35 Other retinal disorders
0.000 0.977 0.023
K26.3 Acute without haemorrhage or perforation
0.000 0.977 0.023
I78.0 Hereditary haemorrhagic telangiectasia
0.001 0.977 0.022
K22.4 Dyskinesia of oesophagus
0.000 0.978 0.022
I72.3 Aneurysm of iliac artery
0.001 0.978 0.021
H35.8 Other specified retinal disorders
0.000 0.978 0.022
I77 Other disorders of arteries and arterioles
0.001 0.978 0.021
I78.8 Other diseases of capillaries
0.001 0.978 0.021
K22.3 Perforation of oesophagus
0.000 0.978 0.022
I84.6 Residual haemorrhoidal skin tags
0.000 0.978 0.022
I74.5 Embolism and thrombosis of iliac artery
0.001 0.978 0.021
I72.0 Aneurysm of carotid artery
0.001 0.978 0.021
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.978 0.021
K25.3 Acute without haemorrhage or perforation
0.000 0.979 0.021
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.001 0.979 0.020
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.979 0.021
I70.01 Atherosclerosis of aorta (with gangrene)
0.001 0.979 0.020
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.979 0.020
I70.11 Atherosclerosis of renal artery (with gangrene)
0.001 0.979 0.020
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.979 0.020
I70.81 Atherosclerosis of other arteries (with gangrene)
0.001 0.979 0.020
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.979 0.020
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.001 0.979 0.020
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.001 0.979 0.020
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.979 0.020
K22.0 Achalasia of cardia
0.000 0.980 0.020
K22.2 Oesophageal obstruction
0.000 0.980 0.020
H35.0 Background retinopathy and retinal vascular changes
0.000 0.980 0.020
I74.8 Embolism and thrombosis of other arteries
0.001 0.980 0.019
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.001 0.980 0.019
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.001 0.980 0.019
I74.0 Embolism and thrombosis of abdominal aorta
0.001 0.980 0.019
K22.7 Barrett's oesophagus
0.000 0.980 0.020
K22.5 Diverticulum of oesophagus, acquired
0.000 0.980 0.019
K25.4 Chronic or unspecified with haemorrhage
0.000 0.981 0.019
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.981 0.019
K28 Gastrojejunal ulcer
0.000 0.981 0.019
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.981 0.019
J44 Other chronic obstructive pulmonary disease
0.000 0.981 0.019
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.001 0.981 0.018
I73 Other peripheral vascular diseases
0.001 0.981 0.018
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.981 0.019
H30-H36 Disorders of choroid and retina
0.000 0.982 0.018
I72.8 Aneurysm of other specified arteries
0.001 0.982 0.017
H35.9 Retinal disorder, unspecified
0.000 0.982 0.018
K20 Oesophagitis
0.000 0.982 0.018
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.982 0.018
K25.5 Chronic or unspecified with perforation
0.000 0.982 0.018
K25.2 Acute with both haemorrhage and perforation
0.000 0.982 0.018

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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