TreeWAS – Variant ID: rs35208507

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.0 Calculus of kidney	1.000	0.000	0.000
N20 Calculus of kidney and ureter	1.000	0.000	0.000
N20.1 Calculus of ureter	1.000	0.000	0.000
N20.2 Calculus of kidney with calculus of ureter	0.999	0.001	0.000
N21 Calculus of lower urinary tract	0.984	0.016	0.000
N20-N23 Urolithiasis	0.984	0.016	0.000
N21.0 Calculus in bladder	0.983	0.017	0.000
N21.1 Calculus in urethra	0.907	0.093	0.000
I10 Essential (primary) hypertension	0.000	0.160	0.840
N20.9 Urinary calculus, unspecified	0.815	0.185	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.705	0.295	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.705	0.295	0.000
I10-I15 Hypertensive diseases	0.000	0.389	0.611
I15 Secondary hypertension	0.000	0.417	0.583
I15.1 Hypertension secondary to other renal disorders	0.000	0.439	0.561
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.506	0.494	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.506	0.494	0.000
N21.8 Other lower urinary tract calculus	0.492	0.507	0.001
I15.9 Seconday hypertension, unspecified	0.000	0.534	0.466
I13 Hypertensive heart and renal disease	0.000	0.562	0.438
I12 Hypertensive renal disease	0.000	0.571	0.429
I15.8 Other secondary hypertension	0.000	0.582	0.418
I15.2 Hypertension secondary to endocrine disorders	0.000	0.582	0.418
I15.0 Renovascular hypertension	0.000	0.632	0.368
I12.0 Hypertensive renal disease with renal failure	0.000	0.650	0.350
I11 Hypertensive heart disease	0.000	0.652	0.347
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.686	0.314
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.686	0.314
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.686	0.314
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.686	0.314
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.750	0.250
I12.9 Hypertensive renal disease without renal failure	0.000	0.772	0.228
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.843	0.156
N18.3 Chronic kidney disease, stage 3	0.000	0.906	0.094
N23 Unspecified renal colic	0.027	0.973	0.000
N18 Chronic renal failure	0.000	0.974	0.026
N18.4 Chronic kidney disease, stage 4	0.000	0.980	0.020
N18.9 Chronic renal failure, unspecified	0.000	0.981	0.019
N18.1 Chronic kidney disease, stage 1	0.000	0.982	0.018
N18.5 Chronic kidney disease, stage 5	0.000	0.983	0.017
N17-N19 Renal failure	0.000	0.983	0.017
N17.9 Acute renal failure, unspecified	0.000	0.983	0.017
N17 Acute renal failure	0.000	0.984	0.016
N18.2 Chronic kidney disease, stage 2	0.000	0.986	0.014
N18.8 Other chronic renal failure	0.000	0.986	0.013
N17.2 Acute renal failure with medullary necrosis	0.000	0.988	0.012
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.988	0.012
N19 Unspecified renal failure	0.000	0.989	0.011
N17.8 Other acute renal failure	0.000	0.989	0.011
N18.0 End-stage renal disease	0.000	0.990	0.010
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.991	0.009
N17.0 Acute renal failure with tubular necrosis	0.000	0.991	0.009
I78.1 Naevus, nonneoplastic	0.000	0.992	0.008
Z90.5 Acquired absence of kidney	0.007	0.993	0.000
E66.8 Other obesity	0.007	0.993	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.993	0.007
C67 Malignant neoplasm of bladder	0.007	0.993	0.000
G31.8 Other specified degenerative diseases of nervous system	0.007	0.993	0.000
C67.6 Ureteric orifice	0.006	0.994	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.994	0.006
C67.2 Lateral wall of bladder	0.006	0.994	0.000
C67.9 Bladder, unspecified	0.006	0.994	0.000
C67.3 Anterior wall of bladder	0.006	0.994	0.000
C71.9 Brain, unspecified	0.000	0.994	0.006
C67.4 Posterior wall of bladder	0.006	0.994	0.000
I61 Intracerebral haemorrhage	0.000	0.994	0.006
C67.1 Dome of bladder	0.006	0.994	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.994	0.006
C67.5 Bladder neck	0.006	0.994	0.000
H26.9 Cataract, unspecified	0.006	0.994	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.994	0.006
C67.0 Trigone of bladder	0.005	0.995	0.000
C67.7 Urachus	0.005	0.995	0.000
C71 Malignant neoplasm of brain	0.000	0.995	0.005
G25.0 Essential tremor	0.005	0.995	0.000
C71.1 Frontal lobe	0.000	0.995	0.005
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.995	0.005
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.995	0.005
C67.8 Overlapping lesion of bladder	0.005	0.995	0.000
I61.8 Other intracerebral haemorrhage	0.000	0.995	0.005
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.995	0.005
C71.2 Temporal lobe	0.000	0.995	0.005
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.995	0.005
C64-C68 Malignant neoplasms of urinary tract	0.005	0.995	0.000
C66 Malignant neoplasm of ureter	0.005	0.995	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
L50.9 Urticaria, unspecified	0.000	0.995	0.005
C71.3 Parietal lobe	0.000	0.995	0.005
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.995	0.005
I22.8 Subsequent myocardial infarction of other sites	0.000	0.996	0.004
G44.2 Tension-type headache	0.004	0.996	0.000
C71.4 Occipital lobe	0.000	0.996	0.004
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.996	0.004
C65 Malignant neoplasm of renal pelvis	0.004	0.996	0.000
I22 Subsequent myocardial infarction	0.000	0.996	0.004
I78 Diseases of capillaries	0.000	0.996	0.004
C90.0 Multiple myeloma	0.000	0.996	0.004
C71.8 Overlapping lesion of brain	0.000	0.996	0.004
C71.7 Brain stem	0.000	0.996	0.004
C71.5 Cerebral ventricle	0.000	0.996	0.004
M85.6 Other cyst of bone	0.004	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.996	0.004
C68 Malignant neoplasm of other and unspecified urinary organs	0.004	0.996	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.004	0.996	0.000
C71.6 Cerebellum	0.000	0.996	0.004
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.996	0.004
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.996	0.004
M85.8 Other specified disorders of bone density and structure	0.004	0.996	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.996	0.004
M50.2 Other cervical disk displacement	0.000	0.996	0.004
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.004	0.996	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.000	0.996	0.003
L65.9 Nonscarring hair loss, unspecified	0.000	0.996	0.004
C68.0 Urethra	0.003	0.996	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.003	0.996	0.000
M85.66 Other cyst of bone (Lower leg)	0.003	0.997	0.000
O44.1 Placenta praevia with haemorrhage	0.003	0.997	0.000
M85 Other disorders of bone density and structure	0.003	0.997	0.000
I78.8 Other diseases of capillaries	0.000	0.997	0.003
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.997	0.003
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.997	0.003
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
G97.8 Other postprocedural disorders of nervous system	0.003	0.997	0.000
M85.68 Other cyst of bone (Other)	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.997	0.003
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.997	0.003
Z01.4 Gynaecological examination (general)(routine)	0.000	0.997	0.003
M85.69 Other cyst of bone (Site unspecified)	0.003	0.997	0.000
M85.63 Other cyst of bone (Forearm)	0.003	0.997	0.000
M85.62 Other cyst of bone (Upper arm)	0.003	0.997	0.000
M85.61 Other cyst of bone (Shoulder region)	0.003	0.997	0.000
M85.60 Other cyst of bone (Multiple sites)	0.003	0.997	0.000
C68.8 Overlapping lesion of urinary organs	0.003	0.997	0.000
C68.1 Paraurethral glands	0.003	0.997	0.000
J35.0 Chronic tonsillitis	0.003	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.997	0.003
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
M85.64 Other cyst of bone (Hand)	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.997	0.000
M31.3 Wegener's granulomatosis	0.000	0.997	0.003
C68.9 Urinary organ, unspecified	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.003	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.003	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.003	0.997	0.000
N10 Acute tubulo-interstitial nephritis	0.003	0.997	0.000
M85.9 Disorder of bone density and structure, unspecified	0.003	0.997	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.003	0.997	0.000
M85.22 Hyperostosis of skull-Upper arm	0.003	0.997	0.000
S05.1 Contusion of eyeball and orbital tissues	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.997	0.003
M85.0 Fibrous dysplasia (monostotic)	0.003	0.997	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.003	0.997	0.000
M85.20 Hyperostosis of skull-Mult sites	0.002	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.997	0.003
G25.1 Drug-induced tremor	0.002	0.997	0.000
M85.29 Hyperostosis of skull-Site unspec	0.002	0.997	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.997	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.997	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.997	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.997	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.997	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.997	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.997	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
N13.6 Pyonephrosis	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.002	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.002	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.002	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.002	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.998	0.002
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.002	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.002	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.002	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.002	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.002	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.002	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.002	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.002	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.002	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.002	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.002	0.998	0.000
M85.38 Osteitis condensans (Other)	0.002	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.002	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.002	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.002	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.002	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.002	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.002	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.002	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.002	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.002	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.002	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.002	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.002	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.002	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.002	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.002	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
I60-I69 Cerebrovascular diseases	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.998	0.002
I67 Other cerebrovascular diseases	0.000	0.998	0.002
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.998	0.002
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.002
K11.2 Sialoadenitis	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
O44 Placenta praevia	0.002	0.998	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.002	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.002	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.002	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.002	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.002	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.002	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.002	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
L65 Other nonscarring hair loss	0.000	0.998	0.002
E66.2 Extreme obesity with alveolar hypoventilation	0.002	0.998	0.000
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.998	0.002
E66 Obesity	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
L60.9 Nail disorder, unspecified	0.000	0.998	0.002
L82 Seborrhoeic keratosis	0.000	0.998	0.002
G44 Other headache syndromes	0.002	0.998	0.000
R18 Ascites	0.000	0.998	0.002
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
Z50.0 Cardiac rehabilitation	0.000	0.998	0.002
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.002
Z47.8 Other specified orthopaedic follow-up care	0.000	0.998	0.002
Chapter IX Diseases of the circulatory system	0.000	0.998	0.002
Z39.0 Care and examination immediately after delivery	0.000	0.998	0.002
G00 Bacterial meningitis, not elsewhere classified	0.000	0.998	0.002
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
L50 Urticaria	0.000	0.998	0.002
Q76.0 Spina bifida occulta	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
Z39.2 Routine postpartum follow-up	0.000	0.998	0.002
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
N15 Other renal tubulo-interstitial diseases	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.998	0.002
I67.5 Moyamoya disease	0.000	0.998	0.002
I67.4 Hypertensive encephalopathy	0.000	0.998	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.998	0.002
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.998	0.002
J35.2 Hypertrophy of adenoids	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
N13 Obstructive and reflux uropathy	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.000	0.998	0.002
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.998	0.002
K92.0 Haematemesis	0.000	0.998	0.002
L65.8 Other specified nonscarring hair loss	0.000	0.998	0.002
L65.2 Alopecia mucinosa	0.000	0.998	0.002
L65.1 Anagen effluvium	0.000	0.998	0.002
L65.0 Telogen effluvium	0.000	0.998	0.002
E66.1 Drug-induced obesity	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.998	0.002
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.998	0.002
G44.1 Vascular headache, not elsewhere classified	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
M31 Other necrotising vasculopathies	0.000	0.998	0.002
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.002
Q23.2 Congenital mitral stenosis	0.000	0.998	0.002
W29.9 Unspecified place	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.998	0.002
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
M31.9 Necrotising vasculopathy, unspecified	0.000	0.998	0.002
L50.8 Other urticaria	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
G00.8 Other bacterial meningitis	0.000	0.998	0.002
G00.3 Staphylococcal meningitis	0.000	0.998	0.002
G00.2 Streptococcal meningitis	0.000	0.998	0.002
G00.0 Haemophilus meningitis	0.000	0.998	0.002
L50.6 Contact urticaria	0.000	0.998	0.002
L50.5 Cholinergic urticaria	0.000	0.998	0.002
L50.4 Vibratory urticaria	0.000	0.998	0.002
L50.3 Dermatographic urticaria	0.000	0.998	0.002
L50.2 Urticaria due to cold and heat	0.000	0.998	0.002
O90 Complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
M76.66 Achilles tendinitis (Lower leg)	0.000	0.998	0.002
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.001	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.002
Q76.5 Cervical rib	0.002	0.998	0.000
I68.0 Cerebral amyloid angiopathy	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.000	0.998	0.002
M31.1 Thrombotic microangiopathy	0.000	0.998	0.002
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.998	0.002
N14.4 Toxic nephropathy, not elsewhere classified	0.001	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.001	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.001	0.998	0.000
N14.0 Analgesic nephropathy	0.001	0.998	0.000
G03 Meningitis due to other and unspecified causes	0.000	0.998	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.001
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.998	0.001
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
N70.0 Acute salpingitis and oophoritis	0.000	0.998	0.002
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
C90.3 Solitary plasmacytoma	0.000	0.998	0.002
M31.0 Hypersensitivity angiitis	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.001	0.998	0.000
N15.0 Balkan nephropathy	0.001	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.002	0.998	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.002	0.998	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.001	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
H35.8 Other specified retinal disorders	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.000	0.998	0.002
O90.0 Disruption of Caesarean section wound	0.000	0.998	0.002
I00-I02 Acute rheumatic fever	0.000	0.998	0.001
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
G03.9 Meningitis, unspecified	0.000	0.998	0.002
G44.3 Chronic posttraumatic headache	0.001	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.000	0.998	0.001
O90.1 Disruption of perineal obstetric wound	0.000	0.998	0.001
V04.1 Traffic accident	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.998	0.001
M31.7 Microscopic polyangiitis	0.000	0.998	0.001
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.998	0.001
M31.2 Lethal midline granuloma	0.000	0.998	0.001
M43.1 Spondylolisthesis	0.000	0.998	0.001
M75.3 Calcific tendinitis of shoulder	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.001	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.998	0.001
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.998	0.001
J35 Chronic diseases of tonsils and adenoids	0.002	0.998	0.000
C44.1 Skin of eyelid, including canthus	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.998	0.002
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.998	0.001
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.998	0.001
O24 Diabetes mellitus in pregnancy	0.000	0.998	0.002
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.998	0.001
G04.1 Tropical spastic paraplegia	0.000	0.998	0.001
G04.0 Acute disseminated encephalitis	0.000	0.998	0.001
G31.9 Degenerative disease of nervous system, unspecified	0.002	0.998	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.998	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.001
N15.1 Renal and perinephric abscess	0.001	0.998	0.000
N99.5 Malfunction of external stoma of urinary tract	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
N03.9 Unspecified	0.000	0.998	0.002
Z39 Postpartum care and examination	0.000	0.998	0.002
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.998	0.001
O90.5 Postpartum thyroiditis	0.000	0.998	0.001
O90.4 Postpartum acute renal failure	0.000	0.998	0.001
O90.3 Cardiomyopathy in the puerperium	0.000	0.998	0.001
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.998	0.001
B00.1 Herpesviral vesicular dermatitis	0.001	0.999	0.000
G03.8 Meningitis due to other specified causes	0.000	0.999	0.001
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.999	0.001
G03.1 Chronic meningitis	0.000	0.999	0.001
G03.0 Nonpyogenic meningitis	0.000	0.999	0.001
Q65 Congenital deformities of hip	0.001	0.999	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.999	0.001
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.999	0.001
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.999	0.001
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.999	0.001
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.999	0.001
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.999	0.001
L60.2 Onychogryphosis	0.000	0.999	0.001
Z04.3 Examination and observation following other accident	0.001	0.999	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
L60 Nail disorders	0.000	0.999	0.001
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.999	0.000
I02 Rheumatic chorea	0.000	0.999	0.001
I01 Rheumatic fever with heart involvement	0.000	0.999	0.001
M45 Ankylosing spondylitis	0.000	0.999	0.001
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.999	0.001
M43.12 Spondylolisthesis (Cervical region)	0.000	0.999	0.001
E66.0 Obesity due to excess calories	0.001	0.999	0.000
F43.2 Adjustment disorders	0.000	0.999	0.001
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.999	0.001
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.999	0.001
S70 Superficial injury of hip and thigh	0.000	0.999	0.001
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.999	0.001
O90.9 Complication of the puerperium, unspecified	0.000	0.999	0.001
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.999	0.001
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.999	0.001
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.999	0.001
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.999	0.001
M54.50 Low back pain (Multiple sites in spine)	0.001	0.999	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.999	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.999	0.001
G44.8 Other specified headache syndromes	0.001	0.999	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.001	0.999	0.000
N99.2 Postprocedural adhesions of vagina	0.001	0.999	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.999	0.001
H05.2 Exophthalmic conditions	0.001	0.999	0.000
K70.0 Alcoholic fatty liver	0.000	0.999	0.001
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.999	0.001
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.999	0.001
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.999	0.001
S80.8 Other superficial injuries of lower leg	0.001	0.999	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.999	0.001
N97.9 Female infertility, unspecified	0.001	0.999	0.000
S70.0 Contusion of hip	0.000	0.999	0.001
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.999	0.001
Chapter XIV Diseases of the genitourinary system	0.001	0.999	0.000
F43.0 Acute stress reaction	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations