TreeWAS – Variant ID: rs35211576

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I67 Other cerebrovascular diseases	0.977	0.023	0.000
I10-I15 Hypertensive diseases	0.976	0.024	0.000
I60-I69 Cerebrovascular diseases	0.974	0.026	0.000
Chapter IX Diseases of the circulatory system	0.968	0.032	0.000
I08.0 Disorders of both mitral and aortic valves	0.963	0.037	0.000
I05-I09 Chronic rheumatic heart diseases	0.963	0.037	0.000
I08 Multiple valve diseases	0.962	0.038	0.000
I67.2 Cerebral atherosclerosis	0.952	0.048	0.000
I67.1 Cerebral aneurysm, nonruptured	0.952	0.048	0.000
I63 Cerebral infarction	0.940	0.060	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.905	0.095	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.892	0.108	0.000
I67.8 Other specified cerebrovascular diseases	0.884	0.116	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.883	0.117	0.000
I60 Subarachnoid haemorrhage	0.882	0.118	0.000
I63.8 Other cerebral infarction	0.871	0.129	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.830	0.170	0.000
I00-I02 Acute rheumatic fever	0.805	0.195	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.787	0.213	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.775	0.225	0.000
I61 Intracerebral haemorrhage	0.749	0.251	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.743	0.257	0.000
I15 Secondary hypertension	0.743	0.257	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.730	0.269	0.000
I13 Hypertensive heart and renal disease	0.728	0.271	0.000
I09 Other rheumatic heart diseases	0.725	0.275	0.000
I67.4 Hypertensive encephalopathy	0.723	0.277	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.722	0.278	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.720	0.280	0.000
I67.5 Moyamoya disease	0.700	0.300	0.000
I67.3 Progressive vascular leukoencephalopathy	0.700	0.300	0.000
I08.8 Other multiple valve diseases	0.699	0.301	0.000
I00 Rheumatic fever without mention of heart involvement	0.688	0.312	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.686	0.314	0.000
I11 Hypertensive heart disease	0.681	0.319	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.674	0.326	0.000
I67.9 Cerebrovascular disease, unspecified	0.672	0.328	0.000
I06 Rheumatic aortic valve diseases	0.667	0.333	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.662	0.337	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.659	0.341	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.654	0.346	0.000
I60.8 Other subarachnoid haemorrhage	0.653	0.347	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.652	0.348	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.647	0.353	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.645	0.355	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.633	0.367	0.000
I07 Rheumatic tricuspid valve diseases	0.631	0.369	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.624	0.376	0.000
I15.0 Renovascular hypertension	0.620	0.380	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.599	0.401	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.588	0.412	0.000
I61.8 Other intracerebral haemorrhage	0.587	0.413	0.000
I08.9 Multiple valve disease, unspecified	0.586	0.414	0.000
I02 Rheumatic chorea	0.577	0.423	0.000
I01 Rheumatic fever with heart involvement	0.577	0.423	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.565	0.434	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.559	0.441	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.558	0.442	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.555	0.445	0.000
I09.9 Rheumatic heart disease, unspecified	0.554	0.446	0.000
I15.9 Seconday hypertension, unspecified	0.554	0.446	0.000
I65.1 Occlusion and stenosis of basilar artery	0.553	0.446	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.544	0.456	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.538	0.462	0.000
I15.8 Other secondary hypertension	0.533	0.467	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.531	0.469	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.529	0.471	0.000
I15.2 Hypertension secondary to endocrine disorders	0.528	0.472	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.525	0.475	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.524	0.476	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.522	0.478	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.522	0.478	0.000
I09.8 Other specified rheumatic heart diseases	0.519	0.480	0.000
I09.2 Chronic rheumatic pericarditis	0.519	0.480	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.519	0.480	0.000
I09.0 Rheumatic myocarditis	0.519	0.480	0.000
I72 Other aneurysm	0.514	0.486	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.495	0.505	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.492	0.508	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.492	0.508	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.492	0.508	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.492	0.508	0.000
I62 Other nontraumatic intracranial haemorrhage	0.492	0.508	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.488	0.512	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.487	0.513	0.000
I06.0 Rheumatic aortic stenosis	0.485	0.515	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.484	0.516	0.000
I68.0 Cerebral amyloid angiopathy	0.479	0.521	0.000
I06.8 Other rheumatic aortic valve diseases	0.478	0.521	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.478	0.521	0.000
I72.4 Aneurysm of artery of lower extremity	0.477	0.523	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.474	0.526	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.470	0.530	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.468	0.532	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.467	0.533	0.000
I72.0 Aneurysm of carotid artery	0.466	0.534	0.000
I07.9 Tricuspid valve disease, unspecified	0.453	0.547	0.000
I07.8 Other tricuspid valve diseases	0.453	0.547	0.000
I07.2 Tricuspid stenosis with insufficiency	0.453	0.547	0.000
I07.0 Tricuspid stenosis	0.453	0.547	0.000
I05 Rheumatic mitral valve diseases	0.447	0.552	0.000
I15.1 Hypertension secondary to other renal disorders	0.435	0.565	0.000
I06.1 Rheumatic aortic insufficiency	0.431	0.569	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.425	0.574	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.414	0.586	0.000
I01.8 Other acute rheumatic heart disease	0.414	0.586	0.000
I01.2 Acute rheumatic myocarditis	0.414	0.586	0.000
I01.1 Acute rheumatic endocarditis	0.414	0.586	0.000
I01.0 Acute rheumatic pericarditis	0.414	0.586	0.000
I02.9 Rheumatic chorea without heart involvement	0.414	0.586	0.000
I02.0 Rheumatic chorea with heart involvement	0.414	0.586	0.000
I72.8 Aneurysm of other specified arteries	0.410	0.590	0.000
I72.3 Aneurysm of iliac artery	0.410	0.590	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.406	0.594	0.000
I07.1 Tricuspid insufficiency	0.394	0.606	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.393	0.607	0.000
I72.9 Aneurysm of unspecified site	0.385	0.615	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.373	0.627	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.369	0.631	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.369	0.631	0.000
I70 Atherosclerosis	0.357	0.642	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.340	0.659	0.000
I79.1 Aortitis in diseases classified elsewhere	0.340	0.660	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.340	0.660	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.336	0.664	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.336	0.664	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.336	0.664	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.332	0.667	0.000
I05.9 Mitral valve disease, unspecified	0.326	0.673	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.322	0.677	0.000
I74 Arterial embolism and thrombosis	0.321	0.679	0.000
I05.0 Mitral stenosis	0.318	0.682	0.000
I05.8 Other mitral valve diseases	0.318	0.682	0.000
I72.2 Aneurysm of renal artery	0.309	0.691	0.000
I69 Sequelae of cerebrovascular disease	0.308	0.692	0.000
I62.1 Nontraumatic extradural haemorrhage	0.303	0.697	0.000
I72.1 Aneurysm of artery of upper extremity	0.300	0.700	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.287	0.713	0.001
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.284	0.715	0.001
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.282	0.718	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.278	0.722	0.000
I78 Diseases of capillaries	0.274	0.726	0.000
I70.1 Atherosclerosis of renal artery	0.270	0.730	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.269	0.730	0.000
I74.5 Embolism and thrombosis of iliac artery	0.265	0.735	0.000
I70.0 Atherosclerosis of aorta	0.264	0.736	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.258	0.742	0.000
I12 Hypertensive renal disease	0.255	0.745	0.000
I70.8 Atherosclerosis of other arteries	0.253	0.747	0.000
I70.9 Generalised and unspecified atherosclerosis	0.246	0.754	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.246	0.754	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.241	0.759	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.234	0.766	0.000
I05.1 Rheumatic mitral insufficiency	0.233	0.767	0.000
I05.2 Mitral stenosis with insufficiency	0.230	0.770	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.223	0.777	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.221	0.779	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.221	0.779	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.220	0.780	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.218	0.782	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.211	0.789	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.207	0.792	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.196	0.804	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.194	0.806	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.193	0.807	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.189	0.811	0.000
I78.9 Disease of capillaries, unspecified	0.186	0.813	0.000
I69.3 Sequelae of cerebral infarction	0.186	0.814	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.181	0.818	0.000
I71 Aortic aneurysm and dissection	0.181	0.819	0.000
I65.2 Occlusion and stenosis of carotid artery	0.179	0.821	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.178	0.822	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.178	0.822	0.000
I74.8 Embolism and thrombosis of other arteries	0.177	0.822	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.177	0.823	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.172	0.828	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.167	0.833	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.167	0.833	0.000
I78.8 Other diseases of capillaries	0.154	0.846	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.152	0.848	0.000
I28 Other diseases of pulmonary vessels	0.149	0.851	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.133	0.867	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.130	0.870	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.130	0.870	0.000
I71.0 Dissection of aorta [any part]	0.127	0.873	0.000
I73 Other peripheral vascular diseases	0.122	0.878	0.000
I78.1 Naevus, nonneoplastic	0.118	0.881	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.116	0.884	0.000
I77 Other disorders of arteries and arterioles	0.113	0.887	0.001
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.108	0.891	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.107	0.893	0.000
I28.1 Aneurysm of pulmonary artery	0.107	0.893	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.107	0.893	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.106	0.894	0.000
I28.8 Other specified diseases of pulmonary vessels	0.097	0.902	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.096	0.904	0.000
I77.3 Arterial fibromuscular dysplasia	0.095	0.905	0.000
I77.8 Other specified disorders of arteries and arterioles	0.094	0.906	0.000
I99 Other and unspecified disorders of circulatory system	0.093	0.907	0.000
I73.8 Other specified peripheral vascular diseases	0.089	0.911	0.000
I97.1 Other functional disturbances following cardiac surgery	0.088	0.911	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.082	0.918	0.000
I77.5 Necrosis of artery	0.081	0.918	0.001
I77.4 Coeliac artery compression syndrome	0.081	0.918	0.001
I12.0 Hypertensive renal disease with renal failure	0.080	0.920	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.079	0.921	0.000
I77.2 Rupture of artery	0.078	0.921	0.001
I97.9 Postprocedural disorder of circulatory system, unspecified	0.077	0.923	0.000
I97.0 Postcardiotomy syndrome	0.077	0.923	0.000
I77.0 Arteriovenous fistula, acquired	0.075	0.924	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.072	0.928	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.069	0.930	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.067	0.933	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.067	0.933	0.000
I26 Pulmonary embolism	0.067	0.933	0.000
I20-I25 Ischaemic heart diseases	0.059	0.941	0.000
S02.20 Fracture of nasal bones (closed)	0.056	0.944	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.053	0.947	0.000
I22 Subsequent myocardial infarction	0.052	0.948	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.051	0.949	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.049	0.950	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.049	0.950	0.001
I98.0 Cardiovascular syphilis	0.049	0.950	0.001
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.045	0.954	0.001
I23 Certain current complications following acute myocardial infarction	0.045	0.955	0.000
I95 Hypotension	0.045	0.955	0.000
I12.9 Hypertensive renal disease without renal failure	0.041	0.958	0.001
I63.9 Cerebral infarction, unspecified	0.041	0.959	0.000
I95.8 Other hypotension	0.038	0.962	0.000
I22.8 Subsequent myocardial infarction of other sites	0.038	0.962	0.000
S02.2 Fracture of nasal bones	0.036	0.964	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.035	0.964	0.000
I23.8 Other current complications following acute myocardial infarction	0.035	0.965	0.000
I95.2 Hypotension due to drugs	0.035	0.965	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.035	0.965	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.034	0.966	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.033	0.967	0.001
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.032	0.967	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.032	0.967	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.032	0.967	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.032	0.967	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.032	0.967	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.032	0.967	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.032	0.967	0.000
K61.0 Anal abscess	0.000	0.967	0.033
I27 Other pulmonary heart diseases	0.030	0.969	0.000
I77.1 Stricture of artery	0.029	0.971	0.000
S02.21 Fracture of nasal bones (open)	0.028	0.972	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.026	0.974	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.023	0.977	0.000
I27.1 Kyphoscoliotic heart disease	0.022	0.978	0.000
I88 Nonspecific lymphadenitis	0.022	0.978	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.022	0.978	0.000
N64.5 Other signs and symptoms in breast	0.000	0.979	0.021
I83 Varicose veins of lower extremities	0.021	0.979	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.020	0.980	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.020	0.980	0.000
S02 Fracture of skull and facial bones	0.019	0.981	0.000
I89.1 Lymphangitis	0.019	0.981	0.000
I88.8 Other nonspecific lymphadenitis	0.019	0.981	0.000
I27.9 Pulmonary heart disease, unspecified	0.019	0.981	0.000
I49.8 Other specified cardiac arrhythmias	0.019	0.981	0.000
I95.0 Idiopathic hypotension	0.018	0.982	0.001
S02.5 Fracture of tooth	0.018	0.982	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.018	0.982	0.000
I27.8 Other specified pulmonary heart diseases	0.017	0.982	0.000
H02.0 Entropion and trichiasis of eyelid	0.018	0.982	0.000
S02.50 Fracture of tooth (closed)	0.017	0.983	0.000
S02.8 Fractures of other skull and facial bones	0.017	0.983	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.016	0.984	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.016	0.984	0.000
I77.6 Arteritis, unspecified	0.007	0.984	0.009
S02.7 Multiple fractures involving skull and facial bones	0.016	0.984	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.015	0.985	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.015	0.985	0.000
I49 Other cardiac arrhythmias	0.015	0.985	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.015	0.985	0.000
I30-I52 Other forms of heart disease	0.015	0.985	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.014	0.985	0.000
I20 Angina pectoris	0.014	0.986	0.000
I20.1 Angina pectoris with documented spasm	0.014	0.986	0.000
B37.8 Candidiasis of other sites	0.014	0.986	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.014	0.986	0.000
I95.1 Orthostatic hypotension	0.014	0.986	0.000
I49.9 Cardiac arrhythmia, unspecified	0.013	0.987	0.000
O48 Prolonged pregnancy	0.000	0.987	0.013
S02.70 Multiple fractures involving skull and facial bones (closed)	0.013	0.987	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.987	0.013
S02.51 Fracture of tooth (open)	0.013	0.987	0.000
I36 Nonrheumatic tricuspid valve disorders	0.013	0.987	0.000
S02.0 Fracture of vault of skull	0.013	0.987	0.000
I49.1 Atrial premature depolarisation	0.013	0.987	0.000
B37 Candidiasis	0.013	0.987	0.000
I87 Other disorders of veins	0.013	0.987	0.000
S02.6 Fracture of mandible	0.013	0.987	0.000
S02.4 Fracture of malar and maxillary bones	0.012	0.988	0.000
I38 Endocarditis, valve unspecified	0.012	0.988	0.000
S02.81 Fractures of other skull and facial bones (open)	0.012	0.988	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.012	0.988	0.000
B37.3 Candidiasis of vulva and vagina	0.012	0.988	0.000
S02.1 Fracture of base of skull	0.012	0.988	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.011	0.988	0.000
I33 Acute and subacute endocarditis	0.011	0.988	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.011	0.988	0.000
I37 Pulmonary valve disorders	0.011	0.989	0.000
B37.7 Candidal septicaemia	0.011	0.989	0.000
I49.3 Ventricular premature depolarisation	0.011	0.989	0.000
I49.2 Junctional premature depolarisation	0.011	0.989	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.011	0.989	0.000
B37.4 Candidiasis of other urogenital sites	0.011	0.989	0.000
I52 Other heart disorders in diseases classified elsewhere	0.011	0.989	0.000
I48 Atrial fibrillation and flutter	0.011	0.989	0.000
I41 Myocarditis in diseases classified elsewhere	0.011	0.989	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.011	0.989	0.000
I32 Pericarditis in diseases classified elsewhere	0.011	0.989	0.000
I81 Portal vein thrombosis	0.011	0.989	0.000
I30 Acute pericarditis	0.011	0.989	0.000
S02.3 Fracture of orbital floor	0.010	0.989	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.989	0.011
I43 Cardiomyopathy in diseases classified elsewhere	0.010	0.989	0.000
I82 Other venous embolism and thrombosis	0.010	0.990	0.000
I33.0 Acute and subacute infective endocarditis	0.010	0.990	0.000
I40 Acute myocarditis	0.010	0.990	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.990	0.010
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.990	0.010
B35-B49 Mycoses	0.010	0.990	0.000
I37.1 Pulmonary valve insufficiency	0.010	0.990	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.010	0.990	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.009	0.990	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.009	0.990	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.009	0.990	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.009	0.990	0.000
S02.01 Fracture of vault of skull (open)	0.009	0.990	0.000
I85 Oesophageal varices	0.008	0.990	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.007	0.990	0.002
B37.6 Candidal endocarditis	0.009	0.991	0.000
B37.5 Candidal meningitis	0.009	0.991	0.000
B37.0 Candidal stomatitis	0.009	0.991	0.000
I87.0 Postphlebitic syndrome	0.009	0.991	0.000
S02.61 Fracture of mandible (open)	0.009	0.991	0.000
I80 Phlebitis and thrombophlebitis	0.009	0.991	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.009	0.991	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.009	0.991	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
I30.1 Infective pericarditis	0.009	0.991	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.991	0.009
B49 Unspecified mycosis	0.009	0.991	0.000
I35 Nonrheumatic aortic valve disorders	0.009	0.991	0.000
I37.9 Pulmonary valve disorder, unspecified	0.008	0.992	0.000
I37.8 Other pulmonary valve disorders	0.008	0.992	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.008	0.992	0.000
I87.8 Other specified disorders of veins	0.008	0.992	0.000
I82.3 Embolism and thrombosis of renal vein	0.008	0.992	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.008	0.992	0.000
I87.9 Disorder of vein, unspecified	0.008	0.992	0.000
S02.00 Fracture of vault of skull (closed)	0.008	0.992	0.000
B35 Dermatophytosis	0.008	0.992	0.000
I24 Other acute ischaemic heart diseases	0.008	0.992	0.000
I49.0 Ventricular fibrillation and flutter	0.008	0.992	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.008	0.992	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.008	0.992	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.008	0.992	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.008	0.992	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.008	0.992	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.008	0.992	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.008	0.992	0.000
I48.4 Atypical atrial flutter	0.008	0.992	0.000
I48.3 Typical atrial flutter	0.008	0.992	0.000
I48.2 Chronic atrial fibrillation	0.008	0.992	0.000
I48.1 Persistent atrial fibrillation	0.008	0.992	0.000
I48.0 Paroxysmal atrial fibrillation	0.008	0.992	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.008	0.992	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.008	0.992	0.000
I30.8 Other forms of acute pericarditis	0.008	0.992	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.008	0.992	0.000
S02.31 Fracture of orbital floor (open)	0.008	0.992	0.000
I35.1 Aortic (valve) insufficiency	0.008	0.992	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.008	0.992	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.008	0.992	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.008	0.992	0.000
B44 Aspergillosis	0.008	0.992	0.000
B37.2 Candidiasis of skin and nail	0.008	0.992	0.000
S02.10 Fracture of base of skull (closed)	0.008	0.992	0.000
I82.1 Thrombophlebitis migrans	0.008	0.992	0.000
Z57.2 Occupational exposure to dust	0.008	0.992	0.000
I40.8 Other acute myocarditis	0.008	0.992	0.000
I40.1 Isolated myocarditis	0.008	0.992	0.000
B37.1 Pulmonary candidiasis	0.008	0.992	0.000
I37.0 Pulmonary valve stenosis	0.007	0.992	0.000
I40.9 Acute myocarditis, unspecified	0.007	0.992	0.000
S02.60 Fracture of mandible (closed)	0.008	0.992	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.007	0.992	0.000
I40.0 Infective myocarditis	0.007	0.992	0.000
I87.1 Compression of vein	0.007	0.993	0.000
B35.1 Tinea unguium	0.007	0.993	0.000
B48 Other mycoses, not elsewhere classified	0.007	0.993	0.000
B47 Mycetoma	0.007	0.993	0.000
B46 Zygomycosis	0.007	0.993	0.000
B45 Cryptococcosis	0.007	0.993	0.000
B43 Chromomycosis and phaeomycotic abscess	0.007	0.993	0.000
B42 Sporotrichosis	0.007	0.993	0.000
B41 Paracoccidioidomycosis	0.007	0.993	0.000
B40 Blastomycosis	0.007	0.993	0.000
B39 Histoplasmosis	0.007	0.993	0.000
B38 Coccidioidomycosis	0.007	0.993	0.000
I27.2 Other secondary pulmonary hypertension	0.007	0.993	0.000
B36 Other superficial mycoses	0.007	0.993	0.000
I51 Complications and ill-defined descriptions of heart disease	0.007	0.993	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.007	0.993	0.000
S02.11 Fracture of base of skull (open)	0.007	0.993	0.000
I82.8 Embolism and thrombosis of other specified veins	0.007	0.993	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.993	0.007
I35.9 Aortic valve disorder, unspecified	0.007	0.993	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.993	0.007
B35.9 Dermatophytosis, unspecified	0.007	0.993	0.000
M34 Systemic sclerosis	0.000	0.993	0.007
I33.9 Acute endocarditis, unspecified	0.006	0.993	0.000
B35.4 Tinea corporis	0.007	0.993	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.993	0.007
B44.1 Other pulmonary aspergillosis	0.007	0.993	0.000
I30.9 Acute pericarditis, unspecified	0.006	0.993	0.000
B37.9 Candidiasis, unspecified	0.006	0.994	0.000
M54.29 Cervicalgia-Site unspe	0.000	0.994	0.006
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.994	0.006
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.006	0.994	0.000
I27.0 Primary pulmonary hypertension	0.006	0.994	0.000
B35.8 Other dermatophytoses	0.006	0.994	0.000
B35.5 Tinea imbricata	0.006	0.994	0.000
B35.2 Tinea manuum	0.006	0.994	0.000
B35.0 Tinea barbae and tinea capitis	0.006	0.994	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.006	0.994	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.994	0.006
I82.0 Budd-Chiari syndrome	0.006	0.994	0.000
I31 Other diseases of pericardium	0.006	0.994	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.994	0.006
I35.2 Aortic (valve) stenosis with insufficiency	0.006	0.994	0.000
M34.1 CR(E)ST syndrome	0.000	0.994	0.006
B44.7 Disseminated aspergillosis	0.006	0.994	0.000
B44.2 Tonsillar aspergillosis	0.006	0.994	0.000
B44.0 Invasive pulmonary aspergillosis	0.006	0.994	0.000
I82.2 Embolism and thrombosis of vena cava	0.006	0.994	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.006	0.994	0.000
B44.8 Other forms of aspergillosis	0.006	0.994	0.000
B35.6 Tinea cruris	0.006	0.994	0.000
B44.9 Aspergillosis, unspecified	0.006	0.994	0.000
Q54.9 Hypospadias, unspecified	0.000	0.994	0.006
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.000	0.994	0.006
I35.8 Other aortic valve disorders	0.006	0.994	0.000
K61 Abscess of anal and rectal regions	0.000	0.994	0.006
I46 Cardiac arrest	0.006	0.994	0.000
Q54.0 Hypospadias, balanic	0.000	0.994	0.006
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.994	0.006
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.006	0.994	0.000
I24.1 Dressler's syndrome	0.005	0.994	0.000
B38.9 Coccidioidomycosis, unspecified	0.005	0.994	0.000
B38.8 Other forms of coccidioidomycosis	0.005	0.994	0.000
B38.7 Disseminated coccidioidomycosis	0.005	0.994	0.000
B38.4 Coccidioidomycosis meningitis	0.005	0.994	0.000
B38.3 Cutaneous coccidioidomycosis	0.005	0.994	0.000
B38.2 Pulmonary coccidioidomycosis, unspecified	0.005	0.994	0.000
B38.1 Chronic pulmonary coccidioidomycosis	0.005	0.994	0.000
B38.0 Acute pulmonary coccidioidomycosis	0.005	0.994	0.000
B39.9 Histoplasmosis, unspecified	0.005	0.994	0.000
B39.5 Histoplasmosis duboisii	0.005	0.994	0.000
B39.4 Histoplasmosis capsulati, unspecified	0.005	0.994	0.000
B39.3 Disseminated histoplasmosis capsulati	0.005	0.994	0.000
B39.2 Pulmonary histoplasmosis capsulati, unspecified	0.005	0.994	0.000
B39.1 Chronic pulmonary histoplasmosis capsulati	0.005	0.994	0.000
B39.0 Acute pulmonary histoplasmosis capsulati	0.005	0.994	0.000
B40.9 Blastomycosis, unspecified	0.005	0.994	0.000
B40.8 Other forms of blastomycosis	0.005	0.994	0.000
B40.7 Disseminated blastomycosis	0.005	0.994	0.000
B40.3 Cutaneous blastomycosis	0.005	0.994	0.000
B40.2 Pulmonary blastomycosis, unspecified	0.005	0.994	0.000
B40.1 Chronic pulmonary blastomycosis	0.005	0.994	0.000
B40.0 Acute pulmonary blastomycosis	0.005	0.994	0.000
B41.9 Paracoccidioidomycosis, unspecified	0.005	0.994	0.000
B41.8 Other forms of paracoccidioidomycosis	0.005	0.994	0.000
B41.7 Disseminated paracoccidioidomycosis	0.005	0.994	0.000
B41.0 Pulmonary paracoccidioidomycosis	0.005	0.994	0.000
B42.9 Sporotrichosis, unspecified	0.005	0.994	0.000
B42.8 Other forms of sporotrichosis	0.005	0.994	0.000
B42.7 Disseminated sporotrichosis	0.005	0.994	0.000
B42.1 Lymphocutaneous sporotrichosis	0.005	0.994	0.000
B42.0 Pulmonary sporotrichosis	0.005	0.994	0.000
B43.9 Chromomycosis, unspecified	0.005	0.994	0.000
B43.8 Other forms of chromomycosis	0.005	0.994	0.000
B43.2 Subcutaneous phaeomycotic abscess and cyst	0.005	0.994	0.000
B43.1 Phaeomycotic brain abscess	0.005	0.994	0.000
B43.0 Cutaneous chromomycosis	0.005	0.994	0.000
B45.9 Cryptococcosis, unspecified	0.005	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations