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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35221806
log Bayes Factor = 7.30552
Chromosome 7   position 7,350,418  (GRCh37) Explore rs35221806 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
E86 Volume depletion
0.984 0.016 0.000
H90-H95 Other disorders of ear
0.981 0.019 0.000
H65-H75 Diseases of middle ear and mastoid
0.979 0.021 0.000
M80-M85 Disorders of bone density and structure
0.974 0.026 0.000
Chapter V Mental and behavioural disorders
0.971 0.029 0.000
M86-M90 Other osteopathies
0.971 0.029 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.969 0.031 0.000
M20-M25 Other joint disorders
0.966 0.034 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.959 0.041 0.000
Chapter IX Diseases of the circulatory system
0.959 0.041 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.956 0.044 0.000
E20-E35 Disorders of other endocrine glands
0.956 0.044 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.953 0.047 0.000
T39.1 4-Aminophenol derivatives
0.953 0.047 0.000
M45-M49 Spondylopathies
0.951 0.049 0.000
E00-E07 Disorders of thyroid gland
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.942 0.058 0.000
H60-H62 Diseases of external ear
0.942 0.058 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.940 0.060 0.000
M35 Other systemic involvement of connective tissue
0.934 0.066 0.000
M46 Other inflammatory spondylopathies
0.930 0.070 0.000
I74 Arterial embolism and thrombosis
0.929 0.071 0.000
H66 Suppurative and unspecified otitis media
0.925 0.075 0.000
E83 Disorders of mineral metabolism
0.918 0.082 0.000
F30-F39 Mood [affective] disorders
0.917 0.083 0.000
M35.0 Sicca syndrome [Sjogren]
0.916 0.084 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.916 0.084 0.000
H90 Conductive and sensorineural hearing loss
0.913 0.087 0.000
S50-S59 Injuries to the elbow and forearm
0.911 0.089 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.910 0.090 0.000
I77 Other disorders of arteries and arterioles
0.908 0.092 0.000
W20-W49 Exposure to inanimate mechanical forces
0.904 0.096 0.000
E88 Other metabolic disorders
0.895 0.105 0.000
H93 Other disorders of ear, not elsewhere classified
0.894 0.106 0.000
M65-M68 Disorders of synovium and tendon
0.890 0.110 0.000
I30-I52 Other forms of heart disease
0.886 0.114 0.000
Y88 Sequelae of surgical and medical care as external cause
0.886 0.114 0.000
M85 Other disorders of bone density and structure
0.885 0.115 0.000
E03 Other hypothyroidism
0.884 0.115 0.000
F32 Depressive episode
0.882 0.118 0.000
M80 Osteoporosis with pathological fracture
0.880 0.120 0.000
M24 Other specific joint derangements
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.873 0.127 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.873 0.127 0.000
S40-S49 Injuries to the shoulder and upper arm
0.869 0.131 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.865 0.135 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.864 0.136 0.000
F32.9 Depressive episode, unspecified
0.861 0.139 0.000
E83.5 Disorders of calcium metabolism
0.860 0.140 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.850 0.150 0.000
H66.9 Otitis media, unspecified
0.849 0.151 0.000
M89 Other disorders of bone
0.848 0.152 0.000
M25 Other joint disorders, not elsewhere classified
0.847 0.153 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.847 0.153 0.000
I50 Heart failure
0.846 0.154 0.000
I74.5 Embolism and thrombosis of iliac artery
0.845 0.155 0.000
V40-V49 Car occupant injured in transport accident
0.844 0.156 0.000
E03.9 Hypothyroidism, unspecified
0.840 0.160 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.840 0.160 0.000
M86 Osteomyelitis
0.839 0.161 0.000
H61 Other disorders of external ear
0.839 0.161 0.000
E04 Other non-toxic goitre
0.836 0.163 0.000
H60 Otitis externa
0.836 0.164 0.000
T23 Burn and corrosion of wrist and hand
0.834 0.166 0.000
H93.1 Tinnitus
0.832 0.168 0.000
A00-A09 Intestinal infectious diseases
0.831 0.169 0.000
I44 Atrioventricular and left bundle-branch block
0.830 0.170 0.000
H72 Perforation of tympanic membrane
0.829 0.171 0.000
I31 Other diseases of pericardium
0.827 0.173 0.000
M87 Osteonecrosis
0.826 0.174 0.000
H71 Cholesteatoma of middle ear
0.823 0.177 0.000
E34 Other endocrine disorders
0.822 0.178 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.822 0.178 0.000
E29 Testicular dysfunction
0.822 0.178 0.000
M85.8 Other specified disorders of bone density and structure
0.821 0.179 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.820 0.180 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.817 0.183 0.000
T21 Burn and corrosion of trunk
0.817 0.183 0.000
B35-B49 Mycoses
0.814 0.186 0.000
I70 Atherosclerosis
0.813 0.187 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.802 0.198 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.801 0.199 0.000
M90 Osteopathies in diseases classified elsewhere
0.800 0.200 0.000
M84 Disorders of continuity of bone
0.799 0.201 0.000
I77.1 Stricture of artery
0.798 0.202 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.797 0.203 0.000
I50.1 Left ventricular failure
0.796 0.204 0.000
Chapter X Diseases of the respiratory system
0.796 0.204 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.795 0.205 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.794 0.206 0.000
H91 Other hearing loss
0.794 0.206 0.000
M65 Synovitis and tenosynovitis
0.792 0.208 0.000
H66.3 Other chronic suppurative otitis media
0.791 0.209 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.791 0.209 0.000
I50.0 Congestive heart failure
0.790 0.210 0.000
F60-F69 Disorders of adult personality and behaviour
0.790 0.210 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.790 0.210 0.000
A04 Other bacterial intestinal infections
0.789 0.211 0.000
E87.3 Alkalosis
0.789 0.211 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.787 0.213 0.000
M35.7 Hypermobility syndrome
0.787 0.213 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.786 0.214 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.782 0.218 0.000
M91-M94 Chondropathies
0.781 0.219 0.000
M22 Disorders of patella
0.781 0.219 0.000
E20 Hypoparathyroidism
0.780 0.220 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.780 0.220 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.780 0.220 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.778 0.222 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.778 0.222 0.000
A30-A49 Other bacterial diseases
0.777 0.222 0.000
E85 Amyloidosis
0.776 0.224 0.000
H70 Mastoiditis and related conditions
0.775 0.225 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
H74 Other disorders of middle ear and mastoid
0.773 0.226 0.000
H61.0 Perichondritis of external ear
0.771 0.229 0.000
J84 Other interstitial pulmonary diseases
0.770 0.230 0.000
E27 Other disorders of adrenal gland
0.770 0.230 0.000
W50-W64 Exposure to animate mechanical forces
0.769 0.231 0.000
B15-B19 Viral hepatitis
0.768 0.232 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.768 0.232 0.000
E87.0 Hyperosmolality and hypernatraemia
0.767 0.233 0.000
E04.1 Non-toxic single thyroid nodule
0.767 0.233 0.000
E06 Thyroiditis
0.767 0.233 0.000
H90.5 Sensorineural hearing loss, unspecified
0.765 0.235 0.000
W29 Contact with other powered hand tools and household machinery
0.764 0.236 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.763 0.237 0.000
B44 Aspergillosis
0.762 0.238 0.000
S40 Superficial injury of shoulder and upper arm
0.761 0.239 0.000
X10-X19 Contact with heat and hot substances
0.761 0.239 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.759 0.241 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.757 0.243 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.756 0.244 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.756 0.244 0.000
M00-M03 Infectious arthropathies
0.755 0.245 0.000
F34 Persistent mood [affective] disorders
0.755 0.245 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.751 0.249 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.751 0.249 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.751 0.249 0.000
H90.3 Sensorineural hearing loss, bilateral
0.751 0.249 0.000
S51 Open wound of forearm
0.751 0.249 0.000
I95 Hypotension
0.750 0.249 0.000
T20 Burn and corrosion of head and neck
0.746 0.253 0.000
M86.9 Osteomyelitis, unspecified
0.745 0.255 0.000
H60.9 Otitis externa, unspecified
0.745 0.255 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.743 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
J81 Pulmonary oedema
0.741 0.259 0.000
I74.8 Embolism and thrombosis of other arteries
0.739 0.261 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.739 0.261 0.000
I38 Endocarditis, valve unspecified
0.738 0.262 0.000
S56 Injury of muscle and tendon at forearm level
0.737 0.263 0.000
X60-X84 Intentional self-harm
0.736 0.263 0.000
M82 Osteoporosis in diseases classified elsewhere
0.736 0.264 0.000
S54 Injury of nerves at forearm level
0.736 0.264 0.000
M89.9 Disorder of bone, unspecified
0.735 0.265 0.000
A65-A69 Other spirochaetal diseases
0.735 0.265 0.000
M25.8 Other specified joint disorders
0.735 0.265 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.735 0.265 0.000
Y86 Sequelae of other accidents
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.732 0.268 0.000
I31.9 Disease of pericardium, unspecified
0.730 0.269 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
E04.2 Non-toxic multinodular goitre
0.728 0.272 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.727 0.273 0.000
M49 Spondylopathies in diseases classified elsewhere
0.727 0.273 0.000
T36 Poisoning by systemic antibiotics
0.726 0.273 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.726 0.274 0.000
E29.1 Testicular hypofunction
0.726 0.274 0.000
E78.2 Mixed hyperlipidaemia
0.724 0.276 0.000
E73 Lactose intolerance
0.724 0.276 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.724 0.276 0.000
M30 Polyarteritis nodosa and related conditions
0.724 0.276 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.724 0.276 0.000
I31.3 Pericardial effusion (noninflammatory)
0.723 0.277 0.000
B44.9 Aspergillosis, unspecified
0.723 0.277 0.000
M24.5 Contracture of joint
0.723 0.277 0.000
M87.9 Osteonecrosis, unspecified
0.722 0.278 0.000
X50-X57 Overexertion, travel and privation
0.721 0.278 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.721 0.279 0.000
E50-E64 Other nutritional deficiencies
0.720 0.280 0.000
I44.0 Atrioventricular block, first degree
0.720 0.280 0.000
I95.1 Orthostatic hypotension
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E84 Cystic fibrosis
0.716 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
I77.0 Arteriovenous fistula, acquired
0.716 0.284 0.000
E23 Hypofunction and other disorders of pituitary gland
0.715 0.285 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.715 0.285 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
Q80-Q89 Other congenital malformations
0.711 0.289 0.000
M24.1 Other articular cartilage disorders
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.290 0.000
T39.0 Salicylates
0.710 0.290 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.291 0.000
S80-S89 Injuries to the knee and lower leg
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
E88.2 Lipomatosis, not elsewhere classified
0.706 0.294 0.000
W25 Contact with sharp glass
0.705 0.295 0.000
I71 Aortic aneurysm and dissection
0.705 0.295 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.704 0.296 0.000
E83.3 Disorders of phosphorus metabolism
0.704 0.296 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.703 0.297 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.703 0.297 0.000
M34 Systemic sclerosis
0.703 0.297 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.702 0.298 0.000
H68 Eustachian salpingitis and obstruction
0.702 0.298 0.000
H67 Otitis media in diseases classified elsewhere
0.702 0.298 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.701 0.299 0.000
I78 Diseases of capillaries
0.701 0.299 0.000
Y95 Nosocomial condition
0.701 0.299 0.000
B65-B83 Helminthiases
0.700 0.300 0.000
S42 Fracture of shoulder and upper arm
0.699 0.301 0.000
M83 Adult osteomalacia
0.698 0.302 0.000
I45 Other conduction disorders
0.698 0.302 0.000
F32.1 Moderate depressive episode
0.698 0.302 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.697 0.302 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.697 0.303 0.000
F20 Schizophrenia
0.697 0.303 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.696 0.304 0.000
F70-F79 Mental retardation
0.696 0.304 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.694 0.305 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.694 0.305 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.694 0.305 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.694 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.694 0.305 0.000
F32.0 Mild depressive episode
0.694 0.306 0.000
W20 Struck by thrown, projected or falling object
0.694 0.306 0.000
E28 Ovarian dysfunction
0.694 0.306 0.000
H69 Other disorders of Eustachian tube
0.692 0.308 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.692 0.308 0.000
M33 Dermatopolymyositis
0.692 0.308 0.000
M32 Systemic lupus erythematosus
0.692 0.308 0.000
M21 Other acquired deformities of limbs
0.691 0.309 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.691 0.309 0.000
I72 Other aneurysm
0.690 0.310 0.000
M67 Other disorders of synovium and tendon
0.689 0.311 0.000
S59 Other and unspecified injuries of forearm
0.689 0.311 0.000
M95.0 Acquired deformity of nose
0.689 0.311 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.688 0.312 0.000
T39.4 Antirheumatics, not elsewhere classified
0.688 0.312 0.000
T39.2 Pyrazolone derivatives
0.688 0.312 0.000
I00-I02 Acute rheumatic fever
0.687 0.313 0.000
F22 Persistent delusional disorders
0.687 0.313 0.000
M24.2 Disorder of ligament
0.686 0.314 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.686 0.314 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.686 0.314 0.000
E32 Diseases of thymus
0.686 0.314 0.000
E31 Polyglandular dysfunction
0.686 0.314 0.000
E30 Disorders of puberty, not elsewhere classified
0.686 0.314 0.000
E26 Hyperaldosteronism
0.686 0.314 0.000
E25 Adrenogenital disorders
0.686 0.314 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.685 0.315 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.684 0.316 0.000
F03 Unspecified dementia
0.684 0.316 0.000
T25 Burn and corrosion of ankle and foot
0.683 0.317 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.683 0.317 0.000
A49 Bacterial infection of unspecified site
0.683 0.317 0.000
I36 Nonrheumatic tricuspid valve disorders
0.682 0.318 0.000
W44 Foreign body entering into or through eye or natural orifice
0.681 0.319 0.000
F30 Manic episode
0.679 0.320 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.679 0.321 0.000
T23.2 Burn of second degree of wrist and hand
0.679 0.321 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.679 0.321 0.000
M88 Paget's disease of bone [osteitis deformans]
0.678 0.322 0.000
Y85 Sequelae of transport accidents
0.678 0.322 0.000
M90.7 Fracture of bone in neoplastic disease
0.678 0.322 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.678 0.322 0.000
I42 Cardiomyopathy
0.677 0.323 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.677 0.323 0.000
E00 Congenital iodine-deficiency syndrome
0.677 0.323 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.677 0.323 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.677 0.323 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.677 0.323 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.675 0.324 0.000
T21.0 Burn of unspecified degree of trunk
0.675 0.324 0.000
F29 Unspecified nonorganic psychosis
0.675 0.325 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.674 0.326 0.000
Y89 Sequelae of other external causes
0.674 0.326 0.000
H90.2 Conductive hearing loss, unspecified
0.673 0.327 0.000
S52 Fracture of forearm
0.673 0.327 0.000
I77.6 Arteritis, unspecified
0.672 0.328 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.672 0.328 0.000
M81 Osteoporosis without pathological fracture
0.672 0.328 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.671 0.329 0.000
M40-M43 Deforming dorsopathies
0.670 0.329 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.670 0.330 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.670 0.330 0.000
M35.8 Other specified systemic involvement of connective tissue
0.670 0.330 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.670 0.330 0.000
M35.5 Multifocal fibrosclerosis
0.670 0.330 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.670 0.330 0.000
M35.2 Behcet's disease
0.670 0.330 0.000
M35.1 Other overlap syndromes
0.670 0.330 0.000
B25-B34 Other viral diseases
0.669 0.331 0.000
E34.0 Carcinoid syndrome
0.668 0.332 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.668 0.332 0.000
H72.0 Central perforation of tympanic membrane
0.668 0.332 0.000
E83.4 Disorders of magnesium metabolism
0.668 0.332 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.667 0.333 0.000
M46.8 Other specified inflammatory spondylopathies
0.667 0.333 0.000
M46.5 Other infective spondylopathies
0.667 0.333 0.000
M46.4 Discitis, unspecified
0.667 0.333 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.667 0.333 0.000
M46.2 Osteomyelitis of vertebra
0.667 0.333 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.667 0.333 0.000
M46.0 Spinal enthesopathy
0.667 0.333 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.666 0.334 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.666 0.334 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.666 0.334 0.000
S40.0 Contusion of shoulder and upper arm
0.666 0.334 0.000
E87.5 Hyperkalaemia
0.666 0.334 0.000
M84.0 Malunion of fracture
0.664 0.336 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.664 0.336 0.000
B99-B99 Other infectious diseases
0.664 0.336 0.000
S50 Superficial injury of forearm
0.664 0.336 0.000
W29.9 Unspecified place
0.664 0.336 0.000
M25.4 Effusion of joint
0.664 0.336 0.000
H66.4 Suppurative otitis media, unspecified
0.663 0.337 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.663 0.337 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.663 0.337 0.000
H66.0 Acute suppurative otitis media
0.663 0.337 0.000
Q50-Q56 Congenital malformations of genital organs
0.663 0.337 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.662 0.338 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.661 0.339 0.000
I44.2 Atrioventricular block, complete
0.661 0.339 0.000
E65-E68 Obesity and other hyperalimentation
0.661 0.339 0.000
F60 Specific personality disorders
0.660 0.340 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.660 0.340 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.659 0.341 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.658 0.342 0.000
E83.8 Other disorders of mineral metabolism
0.658 0.342 0.000
E83.2 Disorders of zinc metabolism
0.658 0.342 0.000
E83.0 Disorders of copper metabolism
0.658 0.342 0.000
F38 Other mood [affective] disorders
0.657 0.343 0.000
F39 Unspecified mood [affective] disorder
0.657 0.343 0.000
I44.3 Other and unspecified atrioventricular block
0.657 0.343 0.000
T23.3 Burn of third degree of wrist and hand
0.657 0.343 0.000
T21.2 Burn of second degree of trunk
0.657 0.343 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.656 0.343 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.656 0.343 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.656 0.343 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.656 0.343 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.656 0.343 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.656 0.343 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.656 0.343 0.000
M25.84 Other specified joint disorders (Hand)
0.656 0.344 0.000
S00-S09 Injuries to the head
0.656 0.344 0.000
F31 Bipolar affective disorder
0.655 0.345 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.655 0.345 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.655 0.345 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.655 0.345 0.000
H90.0 Conductive hearing loss, bilateral
0.655 0.345 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.654 0.346 0.000
E20.9 Hypoparathyroidism, unspecified
0.654 0.346 0.000
H91.9 Hearing loss, unspecified
0.653 0.347 0.000
S58 Traumatic amputation of forearm
0.653 0.347 0.000
S57 Crushing injury of forearm
0.653 0.347 0.000
S55 Injury of blood vessels at forearm level
0.653 0.347 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.653 0.347 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.653 0.347 0.000
E87.4 Mixed disorder of acid-base balance
0.653 0.347 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.652 0.348 0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot
0.651 0.348 0.000
I77.5 Necrosis of artery
0.651 0.349 0.000
I77.4 Coeliac artery compression syndrome
0.651 0.349 0.000
I77.3 Arterial fibromuscular dysplasia
0.651 0.349 0.000
I77.2 Rupture of artery
0.651 0.349 0.000
Q60-Q64 Congenital malformations of the urinary system
0.651 0.349 0.000
H73 Other disorders of tympanic membrane
0.650 0.349 0.000
A04.5 Campylobacter enteritis
0.650 0.350 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.650 0.350 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.649 0.351 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.649 0.351 0.000
I44.6 Other and unspecified fascicular block
0.648 0.351 0.000
W46 Contact with hypodermic needle
0.648 0.352 0.000
W45 Foreign body or object entering through skin
0.648 0.352 0.000
W43 Exposure to vibration
0.648 0.352 0.000
W42 Exposure to noise
0.648 0.352 0.000
W41 Exposure to high-pressure jet
0.648 0.352 0.000
W40 Explosion of other materials
0.648 0.352 0.000
W39 Discharge of firework
0.648 0.352 0.000
W38 Explosion and rupture of other specified pressurised devices
0.648 0.352 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.648 0.352 0.000
W36 Explosion and rupture of gas cylinder
0.648 0.352 0.000
W35 Explosion and rupture of boiler
0.648 0.352 0.000
W34 Discharge from other and unspecified firearms
0.648 0.352 0.000
W33 Rifle, shotgun and larger firearm discharge
0.648 0.352 0.000
W32 Handgun discharge
0.648 0.352 0.000
W31 Contact with other and unspecified machinery
0.648 0.352 0.000
W30 Contact with agricultural machinery
0.648 0.352 0.000
W28 Contact with powered lawn mower
0.648 0.352 0.000
W27 Contact with nonpowered hand tool
0.648 0.352 0.000
W26 Contact with knife, sword or dagger
0.648 0.352 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.648 0.352 0.000
W21 Striking against or struck by sports equipment
0.648 0.352 0.000
M22.2 Patellofemoral disorders
0.648 0.352 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
H61.3 Acquired stenosis of external ear canal
0.648 0.352 0.000
A04.8 Other specified bacterial intestinal infections
0.647 0.353 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.647 0.353 0.000
T17 Foreign body in respiratory tract
0.645 0.354 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.645 0.355 0.000
E34.8 Other specified endocrine disorders
0.644 0.356 0.000
H92 Otalgia and effusion of ear
0.643 0.357 0.000
M25.3 Other instability of joint
0.643 0.357 0.000
I45.6 Preexcitation syndrome
0.643 0.357 0.000
F02 Dementia in other diseases classified elsewhere
0.643 0.357 0.000
F23 Acute and transient psychotic disorders
0.642 0.357 0.000
M45 Ankylosing spondylitis
0.642 0.358 0.000
M89.3 Hypertrophy of bone
0.642 0.358 0.000
E88.9 Metabolic disorder, unspecified
0.642 0.358 0.000
E88.8 Other specified metabolic disorders
0.642 0.358 0.000
E88.3 Tumour lysis syndrome
0.642 0.358 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.642 0.358 0.000
E03.8 Other specified hypothyroidism
0.641 0.358 0.000
H93.9 Disorder of ear, unspecified
0.641 0.359 0.000
H93.8 Other specified disorders of ear
0.641 0.359 0.000
H93.3 Disorders of acoustic nerve
0.641 0.359 0.000
H93.2 Other abnormal auditory perceptions
0.641 0.359 0.000
H93.0 Degenerative and vascular disorders of ear
0.641 0.359 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.641 0.359 0.000
E24 Cushing's syndrome
0.640 0.359 0.000
F25 Schizoaffective disorders
0.640 0.360 0.000
E06.3 Autoimmune thyroiditis
0.639 0.361 0.000
E07 Other disorders of thyroid
0.639 0.361 0.000
F34.1 Dysthymia
0.639 0.361 0.000
M25.83 Other specified joint disorders (Forearm)
0.638 0.362 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.638 0.362 0.000
M66 Spontaneous rupture of synovium and tendon
0.638 0.362 0.000
S10-S19 Injuries to the neck
0.638 0.362 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.638 0.362 0.000
E10-E14 Diabetes mellitus
0.638 0.362 0.000
H60.8 Other otitis externa
0.637 0.363 0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.636 0.364 0.000
I52 Other heart disorders in diseases classified elsewhere
0.635 0.364 0.000
I48 Atrial fibrillation and flutter
0.635 0.364 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.635 0.364 0.000
I41 Myocarditis in diseases classified elsewhere
0.635 0.364 0.000
I40 Acute myocarditis
0.635 0.364 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.635 0.364 0.000
I32 Pericarditis in diseases classified elsewhere
0.635 0.364 0.000
E87.6 Hypokalaemia
0.635 0.365 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.635 0.365 0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use
0.635 0.365 0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures
0.635 0.365 0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use
0.635 0.365 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.635 0.365 0.000
A02 Other Salmonella infections
0.635 0.365 0.000
M85.9 Disorder of bone density and structure, unspecified
0.634 0.366 0.000
M85.6 Other cyst of bone
0.634 0.366 0.000
M85.5 Aneurysmal bone cyst
0.634 0.366 0.000
M85.4 Solitary bone cyst
0.634 0.366 0.000
M85.3 Osteitis condensans
0.634 0.366 0.000
M85.2 Hyperostosis of skull
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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