TreeWAS – Variant ID: rs35513757

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O68 Labour and delivery complicated by foetal stress [distress]	0.006	0.994	0.000
O72 Postpartum haemorrhage	0.005	0.995	0.000
O60-O75 Complications of labour and delivery	0.005	0.995	0.000
K63.5 Polyp of colon	0.000	0.995	0.005
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.005	0.995	0.000
O72.0 Third-stage haemorrhage	0.005	0.995	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.005	0.995	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.005	0.995	0.000
O72.1 Other immediate postpartum haemorrhage	0.005	0.995	0.000
R10.1 Pain localised to upper abdomen	0.000	0.995	0.005
O64 Obstructed labour due to malposition and malpresentation of foetus	0.004	0.995	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.995	0.000
O73 Retained placenta and membranes, without haemorrhage	0.004	0.995	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.004	0.996	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.004	0.996	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.004	0.996	0.000
O66 Other obstructed labour	0.004	0.996	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.004	0.996	0.000
O72.3 Postpartum coagulation defects	0.004	0.996	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.004	0.996	0.000
O74 Complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O71 Other obstetric trauma	0.004	0.996	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.004	0.996	0.000
O62 Abnormalities of forces of labour	0.004	0.996	0.000
O61 Failed induction of labour	0.004	0.996	0.000
O60 Preterm delivery	0.004	0.996	0.000
O70 Perineal laceration during delivery	0.004	0.996	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.004	0.996	0.000
O73.0 Retained placenta, without haemorrhage	0.004	0.996	0.000
O63 Long labour	0.004	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.996	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.003	0.996	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.003	0.996	0.000
O64.5 Obstructed labour due to compound presentation	0.003	0.996	0.000
O64.4 Obstructed labour due to shoulder presentation	0.003	0.996	0.000
O64.3 Obstructed labour due to brow presentation	0.003	0.996	0.000
O64.2 Obstructed labour due to face presentation	0.003	0.996	0.000
O64.1 Obstructed labour due to breech presentation	0.003	0.996	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.996	0.000
O70.0 First degree perineal laceration during delivery	0.003	0.996	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.003	0.996	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.003	0.997	0.000
O75.9 Complication of labour and delivery, unspecified	0.003	0.997	0.000
O75.8 Other specified complications of labour and delivery	0.003	0.997	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.003	0.997	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.003	0.997	0.000
O75.4 Other complications of obstetric surgery and procedures	0.003	0.997	0.000
O75.3 Other infection during labour	0.003	0.997	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.003	0.997	0.000
O75.1 Shock during or following labour and delivery	0.003	0.997	0.000
O75.0 Maternal distress during labour and delivery	0.003	0.997	0.000
O66.9 Obstructed labour, unspecified	0.003	0.997	0.000
O66.8 Other specified obstructed labour	0.003	0.997	0.000
O66.4 Failed trial of labour, unspecified	0.003	0.997	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.003	0.997	0.000
O66.2 Obstructed labour due to unusually large foetus	0.003	0.997	0.000
O66.1 Obstructed labour due to locked twins	0.003	0.997	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.003	0.997	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.003	0.997	0.000
O69.8 Labour and delivery complicated by other cord complications	0.003	0.997	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.003	0.997	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.003	0.997	0.000
O69.3 Labour and delivery complicated by short cord	0.003	0.997	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.003	0.997	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.003	0.997	0.000
O70.2 Third degree perineal laceration during delivery	0.003	0.997	0.000
O60.3 Preterm delivery without spontaneous labour	0.003	0.997	0.000
O60.2 Preterm spontaneous labour with term delivery	0.003	0.997	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.003	0.997	0.000
O60.0 Preterm labour without delivery	0.003	0.997	0.000
O61.9 Failed induction of labour, unspecified	0.003	0.997	0.000
O61.8 Other failed induction of labour	0.003	0.997	0.000
O61.1 Failed instrumental induction of labour	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.003	0.997	0.000
O62.9 Abnormality of forces of labour, unspecified	0.003	0.997	0.000
O62.8 Other abnormalities of forces of labour	0.003	0.997	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.003	0.997	0.000
O62.3 Precipitate labour	0.003	0.997	0.000
O62.2 Other uterine inertia	0.003	0.997	0.000
O62.1 Secondary uterine inertia	0.003	0.997	0.000
O62.0 Primary inadequate contractions	0.003	0.997	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.003	0.997	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.003	0.997	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.003	0.997	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.003	0.997	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.003	0.997	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.003	0.997	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.003	0.997	0.000
O65.0 Obstructed labour due to deformed pelvis	0.003	0.997	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.003	0.997	0.000
O67.8 Other intrapartum haemorrhage	0.003	0.997	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.003	0.997	0.000
O71.9 Obstetric trauma, unspecified	0.003	0.997	0.000
O71.8 Other specified obstetric trauma	0.003	0.997	0.000
O71.7 Obstetric haematoma of pelvis	0.003	0.997	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.003	0.997	0.000
O71.5 Other obstetric injury to pelvic organs	0.003	0.997	0.000
O71.4 Obstetric high vaginal laceration alone	0.003	0.997	0.000
O71.3 Obstetric laceration of cervix	0.003	0.997	0.000
O71.2 Postpartum inversion of uterus	0.003	0.997	0.000
O71.1 Rupture of uterus during labour	0.003	0.997	0.000
O71.0 Rupture of uterus before onset of labour	0.003	0.997	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.003	0.997	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.003	0.997	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.003	0.997	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.003	0.997	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.003	0.997	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.003	0.997	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.003	0.997	0.000
O70.9 Perineal laceration during delivery, unspecified	0.003	0.997	0.000
O70.3 Fourth degree perineal laceration during delivery	0.003	0.997	0.000
O63.9 Long labour, unspecified	0.003	0.997	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.003	0.997	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.997	0.003
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
O63.0 Prolonged first stage (of labour)	0.002	0.997	0.000
S80.9 Superficial injury of lower leg, unspecified	0.003	0.997	0.000
R10 Abdominal and pelvic pain	0.000	0.997	0.003
S80 Superficial injury of lower leg	0.003	0.997	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.997	0.003
S82 Fracture of lower leg, including ankle	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.997	0.000
S82.6 Fracture of lateral malleolus	0.002	0.997	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.997	0.003
S89 Other and unspecified injuries of lower leg	0.002	0.997	0.000
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
R10.2 Pelvic and perineal pain	0.000	0.998	0.002
K92.0 Haematemesis	0.000	0.998	0.002
R10.4 Other and unspecified abdominal pain	0.000	0.998	0.002
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
H40.9 Glaucoma, unspecified	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.000	0.998	0.002
S88 Traumatic amputation of lower leg	0.002	0.998	0.000
S87 Crushing injury of lower leg	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.002	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
O70.1 Second degree perineal laceration during delivery	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
R10.0 Acute abdomen	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
S80.0 Contusion of knee	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.000	0.998	0.002
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.002	0.998	0.000
S89.8 Other specified injuries of lower leg	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.002	0.998	0.000
S89.1 Other specified injuries of lower leg	0.002	0.998	0.000
S89.0 Multiple injuries of lower leg	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
K92 Other diseases of digestive system	0.000	0.998	0.002
O36 Maternal care for other known or suspected foetal problems	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.002
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.998	0.002
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
S02.5 Fracture of tooth	0.002	0.998	0.000
R33 Retention of urine	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.002	0.998	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.002	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.002	0.998	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
R10.3 Pain localised to other parts of lower abdomen	0.000	0.998	0.002
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
O47 False labour	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
O85-O92 Complications predominantly related to the puerperium	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.002	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.002	0.998	0.000
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
O34.0 Maternal care for congenital malformation of uterus	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.001	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
O43 Placental disorders	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
O31 Complications specific to multiple gestation	0.002	0.998	0.000
O40 Polyhydramnios	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
K92.1 Melaena	0.000	0.998	0.002
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
O30 Multiple gestation	0.002	0.998	0.000
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
T33-T35 Frostbite	0.002	0.998	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.998	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998	0.000
T00-T07 Injuries involving multiple body regions	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
S00-S09 Injuries to the head	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
O02.1 Missed abortion	0.000	0.998	0.001
S42.0 Fracture of clavicle	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
S42.00 Fracture of clavicle (closed)	0.002	0.998	0.000
K92.9 Disease of digestive system, unspecified	0.000	0.998	0.002
K92.8 Other specified diseases of digestive system	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
S56 Injury of muscle and tendon at forearm level	0.001	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.001	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.001	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.001	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.001	0.998	0.000
O36.2 Maternal care for hydrops foetalis	0.001	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.001	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.002	0.998	0.000
W19.9 Unspecified place	0.002	0.998	0.000
S61 Open wound of wrist and hand	0.002	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.001	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.001	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.001	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.001	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.001	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.001	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.001	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.001	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.001	0.998	0.000
O22 Venous complications in pregnancy	0.001	0.998	0.000
O21 Excessive vomiting in pregnancy	0.001	0.998	0.000
O25 Malnutrition in pregnancy	0.001	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.001	0.998	0.000
S02.51 Fracture of tooth (open)	0.001	0.998	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.001	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.001	0.998	0.000
K14.8 Other diseases of tongue	0.002	0.998	0.000
O20.0 Threatened abortion	0.001	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.001	0.998	0.000
S48 Traumatic amputation of shoulder and upper arm	0.001	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.001	0.998	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.001	0.998	0.000
S44 Injury of nerves at shoulder and upper arm level	0.001	0.998	0.000
S41 Open wound of shoulder and upper arm	0.001	0.998	0.000
S40 Superficial injury of shoulder and upper arm	0.001	0.998	0.000
S47 Crushing injury of shoulder and upper arm	0.001	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.001	0.998	0.000
O80-O84 Delivery	0.001	0.998	0.000
O00-O08 Pregnancy with abortive outcome	0.001	0.998	0.000
S22.30 Fracture of rib (closed)	0.001	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.001	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.001	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.001	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.001	0.998	0.000
T50.8 Diagnostic agents	0.001	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
T50.5 Appetite depressants	0.001	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.001	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.001	0.998	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
O47.9 False labour, unspecified	0.001	0.998	0.000
O47.0 False labour before 37 completed weeks of gestation	0.001	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.998	0.000
S02.6 Fracture of mandible	0.001	0.998	0.000
S02.3 Fracture of orbital floor	0.001	0.998	0.000
S02.0 Fracture of vault of skull	0.001	0.998	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.001	0.998	0.000
O91 Infections of breast associated with childbirth	0.001	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.001	0.998	0.000
O89 Complications of anaesthesia during the puerperium	0.001	0.998	0.000
O88 Obstetric embolism	0.001	0.998	0.000
O87 Venous complications in the puerperium	0.001	0.998	0.000
O86 Other puerperal infections	0.001	0.998	0.000
O85 Puerperal sepsis	0.001	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.001	0.998	0.000
T75 Effects of other external causes	0.001	0.998	0.000
T74 Maltreatment syndromes	0.001	0.998	0.000
T73 Effects of other deprivation	0.001	0.998	0.000
T70 Effects of air pressure and water pressure	0.001	0.998	0.000
T69 Other effects of reduced temperature	0.001	0.998	0.000
T67 Effects of heat and light	0.001	0.998	0.000
T71 Asphyxiation	0.001	0.998	0.000
T68 Hypothermia	0.001	0.998	0.000
T66 Unspecified effects of radiation	0.001	0.998	0.000
S02.1 Fracture of base of skull	0.001	0.998	0.000
S22.3 Fracture of rib	0.001	0.998	0.000
S42.3 Fracture of shaft of humerus	0.001	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.001	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.001	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.001	0.998	0.000
T39.2 Pyrazolone derivatives	0.001	0.998	0.000
T39.0 Salicylates	0.001	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.001	0.998	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.001	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.001	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.001	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.001	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.001	0.998	0.000
O42 Premature rupture of membranes	0.001	0.998	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.001	0.998	0.000
O48 Prolonged pregnancy	0.001	0.998	0.000
R79 Other abnormal findings of blood chemistry	0.000	0.998	0.001
S22 Fracture of rib(s), sternum and thoracic spine	0.001	0.998	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.001	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.001	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.001	0.998	0.000
T86 Failure and rejection of transplanted organs and tissues	0.001	0.998	0.000
I77.1 Stricture of artery	0.000	0.998	0.001
S42.9 Fracture of shoulder girdle, part unspecified	0.001	0.998	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.001	0.998	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.001	0.998	0.000
S42.4 Fracture of lower end of humerus	0.001	0.998	0.000
S42.1 Fracture of scapula	0.001	0.998	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.001	0.998	0.000
O15 Eclampsia	0.001	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.998	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.001	0.998	0.000
S69 Other and unspecified injuries of wrist and hand	0.001	0.998	0.000
S68 Traumatic amputation of wrist and hand	0.001	0.998	0.000
S67 Crushing injury of wrist and hand	0.001	0.998	0.000
S65 Injury of blood vessels at wrist and hand level	0.001	0.998	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.001	0.998	0.000
S60 Superficial injury of wrist and hand	0.001	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.001	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.001	0.998	0.000
S02.2 Fracture of nasal bones	0.001	0.998	0.000
S42.2 Fracture of upper end of humerus	0.001	0.998	0.000
T39.1 4-Aminophenol derivatives	0.001	0.998	0.000
O02 Other abnormal products of conception	0.001	0.998	0.001
S29 Other and unspecified injuries of thorax	0.001	0.998	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.001	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.001	0.998	0.000
S26 Injury of heart	0.001	0.998	0.000
S25 Injury of blood vessels of thorax	0.001	0.998	0.000
S24 Injury of nerves and spinal cord at thorax level	0.001	0.998	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.001	0.998	0.000
S21 Open wound of thorax	0.001	0.998	0.000
S20 Superficial injury of thorax	0.001	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.001	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.998	0.000
T93 Sequelae of injuries of lower limb	0.001	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.001	0.998	0.000
O31.8 Other complications specific to multiple gestation	0.001	0.998	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.001	0.998	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.001	0.998	0.000
O31.0 Papyraceous foetus	0.001	0.998	0.000
O33.9 Maternal care for disproportion, unspecified	0.001	0.998	0.000
O33.8 Maternal care for disproportion of other origin	0.001	0.998	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.001	0.998	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.001	0.998	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.001	0.998	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.001	0.998	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.001	0.998	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.001	0.998	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.001	0.998	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.001	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.001	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.998	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.001	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.001	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.001	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.001	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.001	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.001	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.001	0.998	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.001	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.001	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.001	0.998	0.000
O41.0 Oligohydramnios	0.001	0.998	0.000
O43.9 Placental disorder, unspecified	0.001	0.998	0.000
O43.8 Other placental disorders	0.001	0.998	0.000
O43.2 Morbidly adherent placenta	0.001	0.998	0.000
O43.1 Malformation of placenta	0.001	0.998	0.000
O43.0 Placental transfusion syndromes	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations