TreeWAS – Variant ID: rs35518360

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
M75 Shoulder lesions	1.000	0.000
M15-M19 Arthrosis	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M70-M79 Other soft tissue disorders	1.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
M13 Other arthritis	1.000	0.000
M50-M54 Other dorsopathies	1.000	0.000
M13.9 Arthritis, unspecified	1.000	0.000
M13.99 Arthritis, unspecified (Site unspecified)	1.000	0.000
M75.1 Rotator cuff syndrome	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
M54 Dorsalgia	0.999	0.001
M54.5 Low back pain	0.999	0.001
M54.56 Low back pain (Lumbar region)	0.999	0.001
M19 Other arthrosis	0.999	0.001
M45-M49 Spondylopathies	0.999	0.001
M25 Other joint disorders, not elsewhere classified	0.999	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.998	0.002
M19.9 Arthrosis, unspecified	0.998	0.002
M19.91 Arthrosis, unspecified (Shoulder region)	0.997	0.003
Chapter V Mental and behavioural disorders	0.997	0.003
Chapter II Neoplasms	0.995	0.005
M16 Coxarthrosis [arthrosis of hip]	0.993	0.007
M17 Gonarthrosis [arthrosis of knee]	0.993	0.007
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.991	0.009
M20 Acquired deformities of fingers and toes	0.991	0.009
Chapter XI Diseases of the digestive system	0.989	0.011
M77 Other enthesopathies	0.987	0.013
Chapter IV Endocrine, nutritional and metabolic diseases	0.986	0.014
M25.7 Osteophyte	0.984	0.016
M17.9 Gonarthrosis, unspecified	0.984	0.016
E11.9 Without complications	0.983	0.017
C15-C26 Malignant neoplasms of digestive organs	0.983	0.017
E11 Non-insulin-dependent diabetes mellitus	0.983	0.017
E10-E14 Diabetes mellitus	0.982	0.018
M16.9 Coxarthrosis, unspecified	0.982	0.018
M75.0 Adhesive capsulitis of shoulder	0.981	0.019
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.980	0.020
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.978	0.022
M75.5 Bursitis of shoulder	0.970	0.030
K40-K46 Hernia	0.970	0.030
K50-K52 Noninfective enteritis and colitis	0.970	0.030
M86-M90 Other osteopathies	0.967	0.033
M13.90 Arthritis, unspecified (Multiple sites)	0.966	0.034
K51 Ulcerative colitis	0.965	0.035
M77.1 Lateral epicondylitis	0.965	0.035
F30-F39 Mood [affective] disorders	0.964	0.036
T20-T25 Burns and corrosions of external body surface, specified by site	0.964	0.036
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.963	0.037
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.962	0.038
K44 Diaphragmatic hernia	0.962	0.038
M25.4 Effusion of joint	0.961	0.039
F60-F69 Disorders of adult personality and behaviour	0.961	0.039
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.959	0.041
M19.99 Arthrosis, unspecified (Site unspecified)	0.957	0.043
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.957	0.043
M16.7 Other secondary coxarthrosis	0.957	0.043
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.956	0.044
Chapter VI Diseases of the nervous system	0.954	0.046
M40-M43 Deforming dorsopathies	0.951	0.049
M46 Other inflammatory spondylopathies	0.951	0.049
M77.12 Lateral epicondylitis (Upper arm)	0.949	0.051
M20.1 Hallux valgus (acquired)	0.949	0.051
M25.76 Osteophyte (Lower leg)	0.947	0.053
D00-D09 In situ neoplasms	0.943	0.057
F31 Bipolar affective disorder	0.942	0.058
T39.0 Salicylates	0.942	0.058
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.942	0.058
K82 Other diseases of gallbladder	0.939	0.061
M17.0 Primary gonarthrosis, bilateral	0.937	0.063
M75.4 Impingement syndrome of shoulder	0.937	0.063
F99-F99 Unspecified mental disorder	0.936	0.064
M45 Ankylosing spondylitis	0.935	0.065
M20.3 Other deformity of hallux (acquired)	0.934	0.066
K51.9 Ulcerative colitis, unspecified	0.932	0.068
T15-T19 Effects of foreign body entering through natural orifice	0.928	0.072
S10-S19 Injuries to the neck	0.926	0.074
K82.8 Other specified diseases of gallbladder	0.925	0.075
M48 Other spondylopathies	0.924	0.076
F60 Specific personality disorders	0.924	0.076
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.923	0.077
C15 Malignant neoplasm of oesophagus	0.915	0.085
M46.9 Inflammatory spondylopathy, unspecified	0.913	0.087
M50 Cervical disk disorders	0.912	0.088
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.908	0.092
G62 Other polyneuropathies	0.900	0.100
M80-M85 Disorders of bone density and structure	0.899	0.101
M75.3 Calcific tendinitis of shoulder	0.898	0.102
T46 Poisoning by agents primarily affecting the cardiovascular system	0.898	0.102
M19.92 Arthrosis, unspecified (Upper arm)	0.895	0.105
D06 Carcinoma in situ of cervix uteri	0.894	0.106
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.894	0.106
M20.4 Other hammer toe(s) (acquired)	0.894	0.106
C78.0 Secondary malignant neoplasm of lung	0.892	0.108
F99 Mental disorder, not otherwise specified	0.892	0.108
C16 Malignant neoplasm of stomach	0.889	0.111
M48.0 Spinal stenosis	0.889	0.111
M25.46 Effusion of joint (Lower leg)	0.889	0.111
M77.9 Enthesopathy, unspecified	0.888	0.112
G62.9 Polyneuropathy, unspecified	0.887	0.113
M87 Osteonecrosis	0.886	0.114
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.885	0.115
C50-C50 Malignant neoplasm of breast	0.882	0.118
D04 Carcinoma in situ of skin	0.880	0.120
M41 Scoliosis	0.879	0.121
M40 Kyphosis and lordosis	0.879	0.121
C51-C58 Malignant neoplasms of female genital organs	0.877	0.123
M23 Internal derangement of knee	0.876	0.124
M15 Polyarthrosis	0.875	0.125
K51.2 Ulcerative (chronic) proctitis	0.872	0.128
M22 Disorders of patella	0.871	0.129
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.870	0.130
C78.2 Secondary malignant neoplasm of pleura	0.868	0.132
E11.4 With neurological complications	0.866	0.134
T92 Sequelae of injuries of upper limb	0.866	0.134
K86 Other diseases of pancreas	0.865	0.135
F31.9 Bipolar affective disorder, unspecified	0.864	0.136
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.864	0.136
T91 Sequelae of injuries of neck and trunk	0.863	0.137
K51.3 Ulcerative (chronic) rectosigmoiditis	0.863	0.137
C56 Malignant neoplasm of ovary	0.860	0.140
S90-S99 Injuries to the ankle and foot	0.860	0.140
D06.9 Cervix, unspecified	0.859	0.141
M23.3 Other meniscus derangements	0.855	0.145
M50.2 Other cervical disk displacement	0.854	0.146
M86 Osteomyelitis	0.849	0.151
C19 Malignant neoplasm of rectosigmoid junction	0.849	0.151
E65-E68 Obesity and other hyperalimentation	0.848	0.152
M06 Other rheumatoid arthritis	0.846	0.154
M48.06 Spinal stenosis (Lumbar region)	0.845	0.155
T23 Burn and corrosion of wrist and hand	0.844	0.156
E11.3 With ophthalmic complications	0.841	0.159
M25.72 Osteophyte (Upper arm)	0.839	0.161
F60.9 Personality disorder, unspecified	0.839	0.161
M49 Spondylopathies in diseases classified elsewhere	0.838	0.162
G35-G37 Demyelinating diseases of the central nervous system	0.838	0.162
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.837	0.163
M25.8 Other specified joint disorders	0.837	0.163
T21 Burn and corrosion of trunk	0.836	0.164
M87.9 Osteonecrosis, unspecified	0.835	0.165
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.833	0.167
M54.55 Low back pain (Thoracolumbar region)	0.832	0.168
M47 Spondylosis	0.832	0.168
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.832	0.168
G90-G99 Other disorders of the nervous system	0.830	0.170
M07 Psoriatic and enteropathic arthropathies	0.830	0.170
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.828	0.172
M41.9 Scoliosis, unspecified	0.828	0.172
K41 Femoral hernia	0.827	0.173
M40.2 Other and unspecified kyphosis	0.827	0.173
C15.9 Oesophagus, unspecified	0.827	0.173
M25.75 Osteophyte (Pelvic region and thigh)	0.826	0.174
M13.0 Polyarthritis, unspecified	0.826	0.174
T17 Foreign body in respiratory tract	0.825	0.175
M25.9 Joint disorder, unspecified	0.823	0.177
F60.3 Emotionally unstable personality disorder	0.819	0.181
F34 Persistent mood [affective] disorders	0.818	0.182
M25.45 Effusion of joint (Pelvic region and thigh)	0.814	0.186
T46.4 Angiotensin-converting-enzyme inhibitors	0.814	0.186
M89 Other disorders of bone	0.812	0.188
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.811	0.189
M54.2 Cervicalgia	0.811	0.189
M06.0 Seronegative rheumatoid arthritis	0.811	0.189
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.810	0.190
K85 Acute pancreatitis	0.810	0.190
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.808	0.192
M25.5 Pain in joint	0.808	0.192
K51.0 Ulcerative (chronic) enterocolitis	0.807	0.192
F80-F89 Disorders of psychological development	0.805	0.195
M45.X2 Ankylosing spondylitis (Cervical region)	0.805	0.195
T47.1 Other antacids and anti-gastric-secretion drugs	0.805	0.195
C50 Malignant neoplasm of breast	0.802	0.198
K65-K67 Diseases of peritoneum	0.800	0.200
M54.1 Radiculopathy	0.800	0.200
M45.X9 Ankylosing spondylitis (Site unspecified)	0.798	0.202
T98 Sequelae of other and unspecified effects of external causes	0.797	0.203
M20.6 Acquired deformity of toe(s), unspecified	0.796	0.204
C76 Malignant neoplasm of other and ill-defined sites	0.794	0.206
Z91 Personal history of risk-factors, not elsewhere classified	0.793	0.207
G95 Other diseases of spinal cord	0.793	0.207
T18 Foreign body in alimentary tract	0.792	0.208
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.792	0.208
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.791	0.209
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.791	0.209
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.789	0.211
S90 Superficial injury of ankle and foot	0.788	0.212
M81 Osteoporosis without pathological fracture	0.788	0.212
F20 Schizophrenia	0.787	0.213
E20-E35 Disorders of other endocrine glands	0.787	0.213
S19 Other and unspecified injuries of neck	0.787	0.213
M80 Osteoporosis with pathological fracture	0.786	0.214
T43.5 Other and unspecified antipsychotics and neuroleptics	0.785	0.215
C25 Malignant neoplasm of pancreas	0.782	0.218
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.782	0.218
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.781	0.219
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.779	0.220
M53 Other dorsopathies, not elsewhere classified	0.779	0.221
C78.1 Secondary malignant neoplasm of mediastinum	0.779	0.221
M20.0 Deformity of finger(s)	0.778	0.221
M19.0 Primary arthrosis of other joints	0.776	0.224
M41.99 Scoliosis, unspecified (Site unspecified)	0.775	0.225
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.775	0.225
M50.3 Other cervical disk degeneration	0.774	0.226
E11.8 With unspecified complications	0.773	0.226
M25.78 Osteophyte (Other)	0.772	0.228
T92.0 Sequelae of open wound of upper limb	0.771	0.229
M91-M94 Chondropathies	0.770	0.230
Q38-Q45 Other congenital malformations of the digestive system	0.767	0.233
Z91.5 Personal history of self-harm	0.767	0.233
M54.59 Low back pain (Site unspecified)	0.765	0.235
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.765	0.235
T95 Sequelae of burns, corrosions and frostbite	0.764	0.236
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.764	0.236
M25.41 Effusion of joint (Shoulder region)	0.764	0.236
K43 Ventral hernia	0.763	0.237
T39.1 4-Aminophenol derivatives	0.761	0.239
Q20-Q28 Congenital malformations of the circulatory system	0.760	0.240
G95.2 Cord compression, unspecified	0.760	0.240
F31.0 Bipolar affective disorder, current episode hypomanic	0.760	0.240
F69 Unspecified disorder of adult personality and behaviour	0.759	0.241
M19.2 Other secondary arthrosis	0.759	0.241
C16.9 Stomach, unspecified	0.758	0.242
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.758	0.242
M77.4 Metatarsalgia	0.757	0.243
T00-T07 Injuries involving multiple body regions	0.757	0.243
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.756	0.244
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.755	0.244
D04.2 Skin of ear and external auricular canal	0.755	0.245
F33 Recurrent depressive disorder	0.755	0.245
Z90 Acquired absence of organs, not elsewhere classified	0.755	0.245
C15.5 Lower third of oesophagus	0.755	0.245
M13.1 Monoarthritis, not elsewhere classified	0.754	0.246
M25.71 Osteophyte (Shoulder region)	0.753	0.247
T92.2 Sequelae of fracture at wrist and hand level	0.753	0.247
T20 Burn and corrosion of head and neck	0.751	0.249
T94 Sequelae of injuries involving multiple and unspecified body regions	0.751	0.249
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.751	0.249
D04.1 Skin of eyelid, including canthus	0.750	0.250
E66 Obesity	0.749	0.251
C16.1 Fundus of stomach	0.748	0.252
M75.2 Bicipital tendinitis	0.748	0.252
E13 Other specified diabetes mellitus	0.748	0.252
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.747	0.252
C20 Malignant neoplasm of rectum	0.747	0.253
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.746	0.254
C50.1 Central portion of breast	0.744	0.256
M54.8 Other dorsalgia	0.744	0.256
Chapter XXI Factors influencing health status and contact with health services	0.743	0.257
K86.0 Alcohol-induced chronic pancreatitis	0.742	0.258
C24.9 Biliary tract, unspecified	0.741	0.259
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.741	0.259
T36 Poisoning by systemic antibiotics	0.741	0.259
M25.56 Pain in joint (Lower leg)	0.740	0.260
T91.1 Sequelae of fracture of spine	0.738	0.262
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.738	0.262
C21 Malignant neoplasm of anus and anal canal	0.737	0.263
K83 Other diseases of biliary tract	0.737	0.263
M19.1 Posttraumatic arthrosis of other joints	0.736	0.264
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.736	0.264
G35 Multiple sclerosis	0.735	0.265
T91.3 Sequelae of injury of spinal cord	0.735	0.265
S14 Injury of nerves and spinal cord at neck level	0.734	0.266
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.734	0.266
M77.91 Enthesopathy, unspecified (Shoulder region)	0.733	0.266
M48.07 Spinal stenosis (Lumbosacral region)	0.733	0.267
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.733	0.267
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.731	0.269
T43.0 Tricyclic and tetracyclic antidepressants	0.730	0.270
C50.8 Overlapping lesion of breast	0.730	0.270
G63 Polyneuropathy in diseases classified elsewhere	0.729	0.271
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.728	0.272
M87.96 Osteonecrosis, unspecified (Lower leg)	0.728	0.272
M15.8 Other polyarthrosis	0.726	0.273
M90 Osteopathies in diseases classified elsewhere	0.725	0.274
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.725	0.275
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.725	0.275
T23.2 Burn of second degree of wrist and hand	0.724	0.276
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.724	0.276
G98 Other disorders of nervous system, not elsewhere classified	0.724	0.276
M77.96 Enthesopathy, unspecified (Lower leg)	0.724	0.276
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.724	0.276
M54.4 Lumbago with sciatica	0.723	0.277
M49.5 Collapsed vertebra in diseases classified elsewhere	0.723	0.277
C23 Malignant neoplasm of gallbladder	0.723	0.277
D04.6 Skin of upper limb, including shoulder	0.723	0.277
K86.3 Pseudocyst of pancreas	0.722	0.278
G30-G32 Other degenerative diseases of the nervous system	0.722	0.278
F60.6 Anxious [avoidant] personality disorder	0.722	0.278
M76 Enthesopathies of lower limb, excluding foot	0.721	0.279
M22.0 Recurrent dislocation of patella	0.720	0.280
C40-C41 Malignant neoplasms of bone and articular cartilage	0.719	0.281
M11 Other crystal arthropathies	0.718	0.281
M17.3 Other posttraumatic gonarthrosis	0.718	0.282
K82.1 Hydrops of gallbladder	0.718	0.282
M40.29 Other and unspecified kyphosis (Site unspecified)	0.718	0.282
M75.8 Other shoulder lesions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M73 Soft tissue disorders in diseases classified elsewhere	0.717	0.283
M12 Other specific arthropathies	0.717	0.283
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283
M08 Juvenile arthritis	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M13.8 Other specified arthritis	0.717	0.283
C64-C68 Malignant neoplasms of urinary tract	0.717	0.283
M81.9 Osteoporosis, unspecified	0.717	0.283
F20.0 Paranoid schizophrenia	0.717	0.283
T33-T35 Frostbite	0.716	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283
M54.0 Panniculitis affecting regions of neck and back	0.716	0.284
M54.54 Low back pain-Thoracic	0.716	0.284
M54.53 Low back pain-Cervicothoracic	0.716	0.284
M54.52 Low back pain-Cervical	0.716	0.284
M54.51 Low back pain-Occipit-atl-axl	0.716	0.284
M19.8 Other specified arthrosis	0.716	0.284
M25.2 Flail joint	0.716	0.284
M25.1 Fistula of joint	0.716	0.284
Z90.4 Acquired absence of other parts of digestive tract	0.716	0.284
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284
S11 Open wound of neck	0.715	0.285
Chapter XX External causes of morbidity and mortality	0.715	0.285
K82.3 Fistula of gallbladder	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.285
F70-F79 Mental retardation	0.715	0.285
M25.84 Other specified joint disorders (Hand)	0.715	0.285
S10 Superficial injury of neck	0.714	0.286
M22.3 Other derangements of patella	0.714	0.286
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.713	0.287
Z90.8 Acquired absence of other organs	0.713	0.287
F34.1 Dysthymia	0.713	0.287
M86.8 Other osteomyelitis	0.712	0.287
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.712	0.288
S60-S69 Injuries to the wrist and hand	0.712	0.288
M16.6 Other secondary coxarthrosis, bilateral	0.712	0.288
M16.4 Posttraumatic coxarthrosis, bilateral	0.712	0.288
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.712	0.288
M17.4 Other secondary gonarthrosis, bilateral	0.712	0.288
M17.2 Posttraumatic gonarthrosis, bilateral	0.712	0.288
M80.9 Unspecified osteoporosis with pathological fracture	0.712	0.288
C80 Malignant neoplasm without specification of site	0.711	0.289
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.711	0.289
T39.4 Antirheumatics, not elsewhere classified	0.711	0.289
T39.2 Pyrazolone derivatives	0.711	0.289
M60-M63 Disorders of muscles	0.711	0.289
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.711	0.289
M46.4 Discitis, unspecified	0.708	0.291
M07.3 Other psoriatic arthropathies	0.707	0.292
M77.8 Other enthesopathies, not elsewhere classified	0.707	0.293
M77.5 Other enthesopathy of foot	0.707	0.293
M77.3 Calcaneal spur	0.707	0.293
M77.2 Periarthritis of wrist	0.707	0.293
F31.7 Bipolar affective disorder, currently in remission	0.707	0.293
M25.79 Osteophyte (Site unspecified)	0.706	0.294
M25.73 Osteophyte (Forearm)	0.706	0.294
M25.70 Osteophyte (Multiple sites)	0.706	0.294
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.705	0.295
E11.7 With multiple complications	0.705	0.295
T17.8 Foreign body in other and multiple parts of respiratory tract	0.705	0.295
E12 Malnutrition-related diabetes mellitus	0.704	0.296
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.704	0.296
M14 Arthropathies in other diseases classified elsewhere	0.704	0.296
M10 Gout	0.703	0.297
F64 Gender identity disorders	0.703	0.297
D02 Carcinoma in situ of middle ear and respiratory system	0.703	0.297
E11.5 With peripheral circulatory complications	0.703	0.297
Z90.5 Acquired absence of kidney	0.702	0.298
Q50-Q56 Congenital malformations of genital organs	0.702	0.298
M13.92 Arthritis, unspecified (Upper arm)	0.701	0.299
S40-S49 Injuries to the shoulder and upper arm	0.700	0.300
C16.2 Body of stomach	0.700	0.300
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.700	0.300
M25.74 Osteophyte (Hand)	0.700	0.300
M15.2 Bouchard's nodes (with arthropathy)	0.700	0.300
M86.9 Osteomyelitis, unspecified	0.700	0.300
M25.47 Effusion of joint (Ankle and foot)	0.699	0.301
K52 Other non-infective gastro-enteritis and colitis	0.699	0.301
Z90.1 Acquired absence of breast(s)	0.699	0.301
M48.09 Spinal stenosis (Site unspecified)	0.699	0.301
M13.93 Arthritis, unspecified (Forearm)	0.696	0.303
C25.2 Tail of pancreas	0.696	0.304
E23 Hypofunction and other disorders of pituitary gland	0.696	0.304
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.696	0.304
T21.2 Burn of second degree of trunk	0.695	0.305
M25.0 Haemarthrosis	0.695	0.305
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.694	0.306
K65 Peritonitis	0.693	0.307
G62.0 Drug-induced polyneuropathy	0.693	0.307
M54.50 Low back pain (Multiple sites in spine)	0.693	0.307
M75.9 Shoulder lesion, unspecified	0.693	0.307
K51.1 Ulcerative (chronic) ileocolitis	0.692	0.308
M77.19 Lateral epicondylitis (Site unspecified)	0.692	0.308
M77.18 Lateral epicondylitis-Other	0.692	0.308
M77.17 Lateral epicondylitis-Ankle/Foot	0.692	0.308
M77.16 Lateral epicondylitis (Lower leg)	0.692	0.308
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.692	0.308
M77.14 Lateral epicondylitis-Hand	0.692	0.308
M77.13 Lateral epicondylitis-Forearm	0.692	0.308
M77.11 Lateral epicondylitis-Shldr region	0.692	0.308
M77.10 Lateral epicondylitis (Multiple sites)	0.692	0.308
F38 Other mood [affective] disorders	0.691	0.309
T25 Burn and corrosion of ankle and foot	0.691	0.309
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.690	0.310
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.690	0.310
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.690	0.310
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.690	0.310
S91 Open wound of ankle and foot	0.690	0.310
K44.1 Diaphragmatic hernia with gangrene	0.689	0.311
M32 Systemic lupus erythematosus	0.689	0.311
M25.49 Effusion of joint (Site unspecified)	0.689	0.311
M25.48 Effusion of joint (Other)	0.689	0.311
M25.44 Effusion of joint (Hand)	0.689	0.311
M25.43 Effusion of joint (Forearm)	0.689	0.311
M25.42 Effusion of joint (Upper arm)	0.689	0.311
M25.40 Effusion of joint (Multiple sites)	0.689	0.311
F68 Other disorders of adult personality and behaviour	0.689	0.311
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.689	0.311
F65 Disorders of sexual preference	0.689	0.311
F63 Habit and impulse disorders	0.689	0.311
F62 Enduring personality changes, not attributable to brain damage and disease	0.689	0.311
F61 Mixed and other personality disorders	0.689	0.311
M50.9 Cervical disk disorder, unspecified	0.688	0.311
K45 Other abdominal hernia	0.688	0.312
S19.9 Unspecified injury of neck	0.687	0.313
M54.22 Cervicalgia (Cervical region)	0.687	0.313
C15.4 Middle third of oesophagus	0.686	0.314
E40-E46 Malnutrition	0.686	0.314
Z89 Acquired absence of limb	0.686	0.314
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.686	0.314
M16.5 Other posttraumatic coxarthrosis	0.684	0.316
F33.1 Recurrent depressive disorder, current episode moderate	0.683	0.317
K42 Umbilical hernia	0.683	0.317
M79 Other soft tissue disorders, not elsewhere classified	0.683	0.317
V80-V89 Other land transport accidents	0.683	0.317
M23.6 Other spontaneous disruption of ligament(s) of knee	0.682	0.318
M42 Spinal osteochondrosis	0.682	0.318
M46.8 Other specified inflammatory spondylopathies	0.682	0.318
M46.5 Other infective spondylopathies	0.682	0.318
M46.3 Infection of intervertebral disk (pyogenic)	0.682	0.318
M46.2 Osteomyelitis of vertebra	0.682	0.318
M46.1 Sacro-iliitis, not elsewhere classified	0.682	0.318
M46.0 Spinal enthesopathy	0.682	0.318
S12 Fracture of neck	0.681	0.319
T43.6 Psychostimulants with abuse potential	0.680	0.320
M23.9 Internal derangement of knee, unspecified	0.679	0.321
M00-M03 Infectious arthropathies	0.679	0.321
M22.9 Disorder of patella, unspecified	0.679	0.321
M25.58 Pain in joint (Other)	0.679	0.321
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.678	0.321
S90.8 Other superficial injuries of ankle and foot	0.678	0.322
T48.6 Antiasthmatics, not elsewhere classified	0.678	0.322
M50.0 Cervical disk disorder with myelopathy	0.677	0.323
T16 Foreign body in ear	0.676	0.324
D01 Carcinoma in situ of other and unspecified digestive organs	0.676	0.324
T21.3 Burn of third degree of trunk	0.676	0.324
F31.8 Other bipolar affective disorders	0.676	0.324
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.676	0.324
T23.3 Burn of third degree of wrist and hand	0.675	0.325
C49 Malignant neoplasm of other connective and soft tissue	0.675	0.325
M16.3 Other dysplastic coxarthrosis	0.674	0.325
M81.99 Osteoporosis, unspecified (Site unspecified)	0.674	0.326
K82.0 Obstruction of gallbladder	0.673	0.327
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.673	0.327
K82.2 Perforation of gallbladder	0.673	0.327
T17.2 Foreign body in pharynx	0.672	0.328
D04.4 Skin of scalp and neck	0.671	0.329
M33 Dermatopolymyositis	0.671	0.329
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.671	0.329
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.670	0.330
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.670	0.330
M45.X6 Ankylosing spondylitis (Lumbar region)	0.670	0.330
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.670	0.330
M45.X4 Ankylosing spondylitis (Thoracic region)	0.670	0.330
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.670	0.330
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.670	0.330
C67 Malignant neoplasm of bladder	0.669	0.331
Q60-Q64 Congenital malformations of the urinary system	0.669	0.331
S90.9 Superficial injury of ankle and foot, unspecified	0.669	0.331
M89.8 Other specified disorders of bone	0.668	0.332
D04.3 Skin of other and unspecified parts of face	0.667	0.332
M25.96 Joint disorder, unspecified (Lower leg)	0.667	0.333
M47.8 Other spondylosis	0.667	0.333
K90-K93 Other diseases of the digestive system	0.667	0.333
M79.5 Residual foreign body in soft tissue	0.667	0.333
M25.6 Stiffness of joint, not elsewhere classified	0.666	0.333
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.666	0.333
M22.2 Patellofemoral disorders	0.666	0.334
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.666	0.334
M15.1 Heberden's nodes (with arthropathy)	0.666	0.334
Q21 Congenital malformations of cardiac septa	0.666	0.334
T19 Foreign body in genito-urinary tract	0.665	0.334
T15 Foreign body on external eye	0.665	0.334
G80-G83 Cerebral palsy and other paralytic syndromes	0.665	0.335
F31.6 Bipolar affective disorder, current episode mixed	0.664	0.335
K51.5 Mucosal proctocolitis	0.664	0.335
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.664	0.335
S17 Crushing injury of neck	0.664	0.336
S15 Injury of blood vessels at neck level	0.664	0.336

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations