TreeWAS – Variant ID: rs35700460

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I25.2 Old myocardial infarction	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000	0.000
Z95.1 Presence of aortocoronary bypass graft	0.999	0.001	0.000
I22 Subsequent myocardial infarction	0.997	0.003	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.996	0.004	0.000
I20 Angina pectoris	0.993	0.007	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.990	0.010	0.000
I20.9 Angina pectoris, unspecified	0.990	0.010	0.000
I21.9 Acute myocardial infarction, unspecified	0.983	0.017	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.977	0.023	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.975	0.025	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.957	0.043	0.000
I21.4 Acute subendocardial myocardial infarction	0.941	0.059	0.000
Z95.2 Presence of prosthetic heart valve	0.930	0.070	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.882	0.118	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.865	0.135	0.000
I20.8 Other forms of angina pectoris	0.857	0.143	0.000
I25.3 Aneurysm of heart	0.849	0.151	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.826	0.174	0.000
I25.5 Ischaemic cardiomyopathy	0.806	0.194	0.000
I22.8 Subsequent myocardial infarction of other sites	0.797	0.203	0.000
I25.6 Silent myocardial ischaemia	0.755	0.245	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.718	0.282	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.707	0.293	0.000
I23 Certain current complications following acute myocardial infarction	0.704	0.296	0.000
I24 Other acute ischaemic heart diseases	0.651	0.349	0.000
I24.8 Other forms of acute ischaemic heart disease	0.594	0.406	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.543	0.457	0.000
I20.1 Angina pectoris with documented spasm	0.530	0.470	0.000
I23.8 Other current complications following acute myocardial infarction	0.524	0.476	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.504	0.495	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.504	0.495	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.504	0.495	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.504	0.495	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.504	0.495	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.504	0.495	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.502	0.498	0.000
Z95.3 Presence of xenogenic heart valve	0.479	0.521	0.000
I24.1 Dressler's syndrome	0.474	0.526	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.468	0.532	0.000
I20.0 Unstable angina	0.454	0.546	0.000
Z95.4 Presence of other heart-valve replacement	0.440	0.560	0.000
I25.4 Coronary artery aneurysm	0.429	0.571	0.001
I24.9 Acute ischaemic heart disease, unspecified	0.271	0.729	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.245	0.755	0.000
Z95.0 Presence of cardiac pacemaker	0.173	0.827	0.000
I50.1 Left ventricular failure	0.046	0.954	0.000
I50.9 Heart failure, unspecified	0.032	0.968	0.000
I50 Heart failure	0.032	0.968	0.000
D12.6 Colon, unspecified	0.000	0.978	0.022
D12.7 Rectosigmoid junction	0.000	0.979	0.021
D12.2 Ascending colon	0.000	0.980	0.020
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.980	0.020
D12.1 Appendix	0.000	0.982	0.018
D12.3 Transverse colon	0.000	0.983	0.017
S22.30 Fracture of rib (closed)	0.014	0.986	0.000
D12.0 Caecum	0.000	0.986	0.014
D41.4 Bladder	0.000	0.986	0.014
D12.8 Rectum	0.000	0.988	0.012
D12.9 Anus and anal canal	0.000	0.989	0.011
S22.3 Fracture of rib	0.011	0.989	0.000
Y44.2 Anticoagulants	0.009	0.991	0.000
Y40 Systemic antibiotics	0.009	0.991	0.000
Y40.0 Penicillins	0.009	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.008	0.992	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.008	0.992	0.000
I50.0 Congestive heart failure	0.008	0.992	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.008	0.992	0.000
S22.31 Fracture of rib (open)	0.008	0.992	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.008	0.992	0.000
D12.4 Descending colon	0.000	0.992	0.008
Y40.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.008	0.992	0.000
Y40.4 Tetracyclines	0.007	0.992	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.007	0.993	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.993	0.007
S27 Injury of other and unspecified intrathoracic organs	0.007	0.993	0.000
Y40.3 Macrolides	0.007	0.993	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
H36.0 Diabetic retinopathy	0.000	0.993	0.007
S20-S29 Injuries to the thorax	0.007	0.993	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.007	0.993	0.000
Y42.7 Androgens and anabolic congeners	0.007	0.993	0.000
S22.4 Multiple fractures of ribs	0.007	0.993	0.000
Y44.5 Thrombolytic drugs	0.007	0.993	0.000
Y40.8 Other systemic antibiotics	0.007	0.993	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.007	0.993	0.000
Y40.2 Chloramphenicol group	0.006	0.993	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.007	0.993	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.993	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.006	0.994	0.000
Y42.5 Other oestrogens and progestogens	0.006	0.994	0.000
S27.3 Other injuries of lung	0.006	0.994	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.994	0.000
Y44.7 Plasma substitutes	0.006	0.994	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.994	0.000
S22.0 Fracture of thoracic vertebra	0.006	0.994	0.000
Y42.2 Antithyroid drugs	0.006	0.994	0.000
S22.9 Fracture of bony thorax, part unspecified	0.006	0.994	0.000
S22.8 Fracture of other parts of bony thorax	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
D41.2 Ureter	0.000	0.994	0.006
Y46.2 Hydantoin derivatives	0.006	0.994	0.000
S27.0 Traumatic pneumothorax	0.006	0.994	0.000
S22.2 Fracture of sternum	0.006	0.994	0.000
S27.1 Traumatic haemothorax	0.006	0.994	0.000
Y44.6 Natural blood and blood products	0.006	0.994	0.000
S27.8 Injury of other specified intrathoracic organs	0.006	0.994	0.000
Z29.2 Other prophylactic chemotherapy	0.006	0.994	0.000
Y41.5 Antiviral drugs	0.006	0.994	0.000
S24 Injury of nerves and spinal cord at thorax level	0.006	0.994	0.000
D41.1 Renal pelvis	0.000	0.994	0.006
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.006	0.994	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.006	0.994	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.006	0.994	0.000
Y58 Bacterial vaccines	0.006	0.994	0.000
S22.5 Flail chest	0.006	0.994	0.000
Y40.5 Aminoglycosides	0.006	0.994	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.006	0.994	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
S29 Other and unspecified injuries of thorax	0.006	0.994	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
Y46.6 Other and unspecified antiepileptics	0.006	0.994	0.000
Y59 Other and unspecified vaccines and biological substances	0.005	0.994	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.994	0.006
Y42.4 Oral contraceptives	0.005	0.994	0.000
Y46.5 Valproic acid	0.005	0.994	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.006	0.994	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.005	0.994	0.000
S22.40 Multiple fractures of ribs (closed)	0.006	0.994	0.000
Y40.6 Rifamycins	0.005	0.994	0.000
Y42.9 Other and unspecified hormone antagonists	0.005	0.994	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.005	0.995	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.005	0.995	0.000
Y53.2 Stimulant laxatives	0.005	0.995	0.000
D41.9 Urinary organ, unspecified	0.000	0.995	0.005
D41.7 Other urinary organs	0.000	0.995	0.005
D41.3 Urethra	0.000	0.995	0.005
S24.1 Other and unspecified injuries of thoracic spinal cord	0.005	0.995	0.000
S09.9 Unspecified injury of head	0.005	0.995	0.000
S22.1 Multiple fractures of thoracic spine	0.005	0.995	0.000
S27.9 Injury of unspecified intrathoracic organ	0.005	0.995	0.000
S27.7 Multiple injuries of intrathoracic organs	0.005	0.995	0.000
S27.6 Injury of pleura	0.005	0.995	0.000
S27.5 Injury of thoracic trachea	0.005	0.995	0.000
S27.4 Injury of bronchus	0.005	0.995	0.000
Y46.7 Anti-Parkinsonism drugs	0.005	0.995	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.005	0.995	0.000
S26 Injury of heart	0.005	0.995	0.000
S25 Injury of blood vessels of thorax	0.005	0.995	0.000
Y53.4 Other laxatives	0.005	0.995	0.000
Y54.4 Loop [high-ceiling] diuretics	0.005	0.995	0.000
Y57 Other and unspecified drugs and medicaments	0.005	0.995	0.000
Y46.8 Antispasticity drugs	0.005	0.995	0.000
Y46.3 Deoxybarbiturates	0.005	0.995	0.000
Y46.1 Oxazolidinediones	0.005	0.995	0.000
Y46.0 Succinimides	0.005	0.995	0.000
Y41.0 Sulphonamides	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
Y42.1 Thyroid hormones and substitutes	0.005	0.995	0.000
S22.41 Multiple fractures of ribs (open)	0.005	0.995	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
Y53.7 Emetics	0.005	0.995	0.000
Y53.5 Digestants	0.005	0.995	0.000
Y53.0 Histamine H2-receptor antagonists	0.005	0.995	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
Y41.4 Anthelminthics	0.005	0.995	0.000
Y41.3 Other antiprotozoal drugs	0.005	0.995	0.000
Y53.6 Antidiarrhoeal drugs	0.005	0.995	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
Y55.5 Anticommon cold drugs	0.005	0.995	0.000
Y55.3 Antitussives	0.005	0.995	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
Y55.0 Oxytocic drugs	0.005	0.995	0.000
Y54.5 Other diuretics	0.005	0.995	0.000
Y55.4 Expectorants	0.005	0.995	0.000
S29.9 Unspecified injury of thorax	0.005	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.005	0.995	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.005	0.995	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.005	0.995	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.005	0.995	0.000
S22.01 Fracture of thoracic vertebra (open)	0.005	0.995	0.000
Y54.3 Benzothiadiazine derivatives	0.005	0.995	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.005	0.995	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.005	0.995	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.005	0.995	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.005	0.995	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
Y54.9 Mineral salts, not elsewhere classified	0.005	0.995	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.005	0.995	0.000
Y53.3 Saline and osmotic laxatives	0.005	0.995	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
Y54.0 Mineralocorticoids	0.005	0.995	0.000
S22.21 Fracture of sternum (open)	0.005	0.995	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.005	0.995	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.004	0.995	0.000
S23.4 Sprain and strain of ribs and sternum	0.005	0.995	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.005	0.995	0.000
S20 Superficial injury of thorax	0.005	0.995	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.004	0.995	0.000
S24.6 Injury of unspecified nerve of thorax	0.004	0.995	0.000
S24.5 Injury of other nerves of thorax	0.004	0.995	0.000
S24.4 Injury of thoracic sympathetic nerves	0.004	0.995	0.000
S24.3 Injury of peripheral nerves of thorax	0.004	0.995	0.000
S24.2 Injury of nerve root of thoracic spine	0.004	0.995	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.004	0.995	0.000
Y54.7 Agents affecting calcification	0.004	0.995	0.000
Y49.2 Other and unspecified antidepressants	0.004	0.995	0.000
S22.20 Fracture of sternum (closed)	0.004	0.995	0.000
C25.2 Tail of pancreas	0.000	0.995	0.005
Y41.1 Antimycobacterial drugs	0.004	0.995	0.000
Y58.0 BCG vaccine	0.004	0.995	0.000
Y57.8 Other drugs and medicaments	0.004	0.995	0.000
Y50.9 Central nervous system stimulant, unspecified	0.004	0.995	0.000
Y50.8 Other central nervous system stimulants	0.004	0.995	0.000
Y50.1 Opioid receptor antagonists	0.004	0.995	0.000
Y50.0 Analeptics	0.004	0.995	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
Y58.9 Other and unspecified bacterial vaccines	0.004	0.996	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.004	0.996	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.004	0.996	0.000
Y58.5 Diphtheria vaccine	0.004	0.996	0.000
Y58.4 Tetanus vaccine	0.004	0.996	0.000
Y58.3 Plague vaccine	0.004	0.996	0.000
Y58.2 Cholera vaccine	0.004	0.996	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
S22.51 Flail chest (open)	0.004	0.996	0.000
S27.2 Traumatic heamopneumothorax	0.004	0.996	0.000
S29.8 Other specified injuries of thorax	0.004	0.996	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.004	0.996	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
Y49.9 Psychotropic drug, unspecified	0.004	0.996	0.000
Y49.7 Psychostimulants with abuse potential	0.004	0.996	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.004	0.996	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
S21 Open wound of thorax	0.004	0.996	0.000
S29.7 Multiple injuries of thorax	0.004	0.996	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.004	0.996	0.000
S23.3 Sprain and strain of thoracic spine	0.004	0.996	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.004	0.996	0.000
S23.1 Dislocation of thoracic vertebra	0.004	0.996	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.004	0.996	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.996	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.996	0.000
Y59.2 Protozoal vaccines	0.004	0.996	0.000
Y59.1 Rickettsial vaccines	0.004	0.996	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.004	0.996	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.004	0.996	0.000
Y47.4 Bromine compounds	0.004	0.996	0.000
Y47.3 Paraldehyde	0.004	0.996	0.000
Y47.2 Chloral derivatives	0.004	0.996	0.000
Y47.0 Barbiturates, not elsewhere classified	0.004	0.996	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
Y57.5 X-ray contrast media	0.004	0.996	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.004	0.996	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.004	0.996	0.000
S29.0 Injury of muscle and tendon at thorax level	0.004	0.996	0.000
Y47.1 Benzodiazepines	0.004	0.996	0.000
S20.1 Other and unspecified superficial injuries of breast	0.004	0.996	0.000
D41.0 Kidney	0.000	0.996	0.004
S25.9 Injury of unspecified blood vessel of thorax	0.004	0.996	0.000
S25.8 Injury of other blood vessels of thorax	0.004	0.996	0.000
S25.7 Injury of multiple blood vessels of thorax	0.004	0.996	0.000
S25.5 Injury of intercostal blood vessels	0.004	0.996	0.000
S25.4 Injury of pulmonary blood vessels	0.004	0.996	0.000
S25.3 Injury of innominate or subclavian vein	0.004	0.996	0.000
S25.2 Injury of superior vena cava	0.004	0.996	0.000
S25.1 Injury of innominate or subclavian artery	0.004	0.996	0.000
S25.0 Injury of thoracic aorta	0.004	0.996	0.000
S26.9 Injury of heart, unspecified	0.004	0.996	0.000
S26.8 Other injuries of heart	0.004	0.996	0.000
S26.0 Injury of heart with haemopericardium	0.004	0.996	0.000
S28.1 Traumatic amputation of part of thorax	0.004	0.996	0.000
S28.0 Crushed chest	0.004	0.996	0.000
Y57.7 Vitamins, not elsewhere classified	0.004	0.996	0.000
Y57.4 Pharmaceutical excipients	0.004	0.996	0.000
Y57.3 Alcohol deterrents	0.004	0.996	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
Y57.1 Lipotropic drugs	0.004	0.996	0.000
Y57.0 Appetite depressants [anorectics]	0.004	0.996	0.000
Y48.5 Therapeutic gases	0.004	0.996	0.000
Y48.1 Parenteral anaesthetics	0.004	0.996	0.000
Y48.0 Inhaled anaesthetics	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
Y43 Primarily systemic agents	0.004	0.996	0.000
Z29.1 Prophylactic immunotherapy	0.004	0.996	0.000
C25.9 Pancreas, unspecified	0.000	0.996	0.004
C25 Malignant neoplasm of pancreas	0.000	0.996	0.004
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.004	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
H57.1 Ocular pain	0.004	0.996	0.000
Y56.3 Emollients, demulcents and protectants	0.004	0.996	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.004	0.996	0.000
Y56.9 Topical agent, unspecified	0.004	0.996	0.000
Y56.8 Other topical agents	0.004	0.996	0.000
Y56.7 Dental drugs, topically applied	0.004	0.996	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
Y56.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
Y56.2 Local astringents and local detergents	0.004	0.996	0.000
Y56.1 Antipruritics	0.004	0.996	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.004	0.996	0.000
S20.0 Contusion of breast	0.004	0.996	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.996	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.996	0.000
Z29 Need for other prophylactic measures	0.004	0.996	0.000
S20.4 Other superficial injuries of back wall of thorax	0.003	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.996	0.000
C25.4 Endocrine pancreas	0.000	0.996	0.003
S21.2 Open wound of back wall of thorax	0.003	0.996	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
C25.7 Other parts of pancreas	0.000	0.997	0.003
Y57.6 Other diagnostic agents	0.003	0.997	0.000
S20.3 Other superficial injuries of front wall of thorax	0.003	0.997	0.000
S21.8 Open wound of other parts of thorax	0.003	0.997	0.000
S21.7 Multiple open wounds of thoracic wall	0.003	0.997	0.000
S21.0 Open wound of breast	0.003	0.997	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.997	0.003
S20.7 Multiple superficial injuries of thorax	0.003	0.997	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.003	0.997	0.000
N04.9 Unspecified	0.000	0.997	0.003
C25.1 Body of pancreas	0.000	0.997	0.003
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.003	0.997	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.003	0.997	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.003	0.997	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.003	0.997	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.003	0.997	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.003	0.997	0.000
S20.2 Contusion of thorax	0.003	0.997	0.000
W44.0 Home	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
Y48.3 Local anaesthetics	0.003	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
C25.0 Head of pancreas	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
S21.9 Open wound of thorax, part unspecified	0.003	0.997	0.000
S21.1 Open wound of front wall of thorax	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.997	0.003
D17.6 Benign lipomatous neoplasm of spermatic cord	0.003	0.997	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.003	0.997	0.000
C25.3 Pancreatic duct	0.000	0.997	0.003
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
C21.0 Anus, unspecified	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.003	0.997	0.000
O47 False labour	0.000	0.997	0.003
Q21.1 Atrial septal defect	0.000	0.997	0.003
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.003	0.997	0.000
N64.9 Disorder of breast, unspecified	0.003	0.997	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.997	0.003
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Y83.5 Amputation of limb(s)	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
O03.4 Incomplete, without complication	0.000	0.997	0.003
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.003	0.997	0.000
I67.9 Cerebrovascular disease, unspecified	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
S09 Other and unspecified injuries of head	0.003	0.997	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.997	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.003	0.997	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.997	0.000
Z29.8 Other specified prophylactic measures	0.002	0.997	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.002	0.998	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.002	0.998	0.000
O47.9 False labour, unspecified	0.000	0.998	0.002
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
S09.8 Other specified injuries of head	0.002	0.998	0.000
S09.2 Traumatic rupture of ear drum	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.998	0.002
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
T87.6 Other and unspecified complications of amputation stump	0.002	0.998	0.000
C17.0 Duodenum	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
S09.7 Multiple injuries of head	0.002	0.998	0.000
S09.1 Injury of muscle and tendon of head	0.002	0.998	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
I47.2 Ventricular tachycardia	0.002	0.998	0.000
Z82.1 Family history of blindness and visual loss	0.002	0.998	0.000
Z82.2 Family history of deafness and hearing loss	0.002	0.998	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
W22.9 Unspecified place	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.002	0.998	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.002	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
G00.1 Pneumococcal meningitis	0.002	0.998	0.000
Z29.0 Isolation	0.002	0.998	0.000
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
D12.5 Sigmoid colon	0.000	0.998	0.002
G25.0 Essential tremor	0.000	0.998	0.002
G00 Bacterial meningitis, not elsewhere classified	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
I51.6 Cardiovascular disease, unspecified	0.002	0.998	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.000	0.998	0.002
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.002	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
C21.1 Anal canal	0.002	0.998	0.000
G00.3 Staphylococcal meningitis	0.002	0.998	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.998	0.000
O04 Medical abortion	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.002	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.998	0.000
R09.1 Pleurisy	0.000	0.998	0.002
S60 Superficial injury of wrist and hand	0.000	0.998	0.002
C79.7 Secondary malignant neoplasm of adrenal gland	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.998	0.002
G00.2 Streptococcal meningitis	0.002	0.998	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
K63.0 Abscess of intestine	0.000	0.998	0.002
S60.2 Contusion of other parts of wrist and hand	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations