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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35729753
log Bayes Factor = 17.3029
Chromosome 12   position 66,672,379  (GRCh37) Explore rs35729753 on Ensembl!
Variant rs35729753 is part of Cluster X0214

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Z51 Other medical care
0.997 0.003 0.000
Z51.1 Chemotherapy session for neoplasm
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.995 0.005 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.995 0.005 0.000
K90-K93 Other diseases of the digestive system
0.995 0.005 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.994 0.006 0.000
K92 Other diseases of digestive system
0.994 0.006 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.991 0.009 0.000
K92.0 Haematemesis
0.990 0.010 0.000
M15-M19 Arthrosis
0.989 0.011 0.000
M17.1 Other primary gonarthrosis
0.987 0.013 0.000
M17 Gonarthrosis [arthrosis of knee]
0.987 0.013 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.986 0.014 0.000
C15-C26 Malignant neoplasms of digestive organs
0.983 0.017 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.979 0.021 0.000
Z85 Personal history of malignant neoplasm
0.972 0.028 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.967 0.033 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.960 0.040 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.959 0.041 0.000
D50-D53 Nutritional anaemias
0.956 0.044 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.954 0.046 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.953 0.047 0.000
C79 Secondary malignant neoplasm of other sites
0.953 0.047 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.949 0.051 0.000
M23 Internal derangement of knee
0.938 0.062 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.937 0.063 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.935 0.065 0.000
K70-K77 Diseases of liver
0.935 0.065 0.000
C18 Malignant neoplasm of colon
0.924 0.076 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.924 0.076 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.920 0.080 0.000
C34 Malignant neoplasm of bronchus and lung
0.920 0.080 0.000
C15 Malignant neoplasm of oesophagus
0.918 0.082 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.917 0.083 0.000
D50 Iron deficiency anaemia
0.917 0.083 0.000
M23.8 Other internal derangements of knee
0.916 0.084 0.000
T81 Complications of procedures, not elsewhere classified
0.914 0.086 0.000
Z40 Prophylactic surgery
0.913 0.087 0.000
Z97 Presence of other devices
0.911 0.089 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.908 0.092 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.908 0.092 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.908 0.092 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.907 0.093 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.907 0.093 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.904 0.096 0.000
K92.1 Melaena
0.904 0.096 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.900 0.100 0.000
Z47 Other orthopaedic follow-up care
0.896 0.104 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.894 0.106 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.887 0.113 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.885 0.115 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.882 0.118 0.000
S60-S69 Injuries to the wrist and hand
0.881 0.119 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.881 0.119 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.880 0.120 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.879 0.121 0.000
C51-C58 Malignant neoplasms of female genital organs
0.879 0.121 0.000
K26 Duodenal ulcer
0.878 0.122 0.000
Z90.7 Acquired absence of genital organ(s)
0.875 0.125 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.875 0.125 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.875 0.125 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.871 0.129 0.000
M45-M49 Spondylopathies
0.871 0.129 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.870 0.130 0.000
C18.7 Sigmoid colon
0.867 0.133 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.864 0.136 0.000
C34.9 Bronchus or lung, unspecified
0.859 0.141 0.000
D50.8 Other iron deficiency anaemias
0.858 0.142 0.000
Z90.2 Acquired absence of lung [part of]
0.858 0.142 0.000
C85.1 B-cell lymphoma, unspecified
0.857 0.143 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.856 0.144 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.854 0.146 0.000
C90.0 Multiple myeloma
0.853 0.147 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.851 0.149 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.847 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.847 0.153 0.000
T42.4 Benzodiazepines
0.845 0.155 0.000
K65-K67 Diseases of peritoneum
0.843 0.157 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.842 0.158 0.000
C15.5 Lower third of oesophagus
0.842 0.158 0.000
C92 Myeloid leukaemia
0.833 0.167 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.829 0.171 0.000
Z46 Fitting and adjustment of other devices
0.828 0.172 0.000
Z82.3 Family history of stroke
0.823 0.177 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.823 0.177 0.000
D60-D64 Aplastic and other anaemias
0.822 0.178 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.822 0.178 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.816 0.184 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.812 0.188 0.000
Z92 Personal history of medical treatment
0.812 0.188 0.000
C54 Malignant neoplasm of corpus uteri
0.809 0.191 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.808 0.192 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.808 0.192 0.000
K31 Other diseases of stomach and duodenum
0.808 0.192 0.000
M31 Other necrotising vasculopathies
0.807 0.193 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.807 0.193 0.000
Z98 Other postsurgical states
0.806 0.194 0.000
Z94 Transplanted organ and tissue status
0.806 0.194 0.000
X60-X84 Intentional self-harm
0.802 0.198 0.000
O80-O84 Delivery
0.802 0.198 0.000
M21 Other acquired deformities of limbs
0.802 0.198 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.801 0.199 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.800 0.200 0.000
Z45 Adjustment and management of implanted device
0.798 0.202 0.000
O60-O75 Complications of labour and delivery
0.798 0.202 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.797 0.203 0.000
S80-S89 Injuries to the knee and lower leg
0.794 0.206 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.793 0.207 0.000
V80-V89 Other land transport accidents
0.792 0.208 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.790 0.210 0.000
K70 Alcoholic liver disease
0.789 0.211 0.000
Z85.6 Personal history of leukaemia
0.788 0.212 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.785 0.215 0.000
C34.1 Upper lobe, bronchus or lung
0.782 0.218 0.000
Z41 Procedures for purposes other than remedying health state
0.782 0.218 0.000
C16 Malignant neoplasm of stomach
0.782 0.218 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.781 0.219 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.780 0.220 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.780 0.220 0.000
Chapter XXII Codes for special purposes
0.780 0.220 0.000
M22 Disorders of patella
0.777 0.223 0.000
Z04 Examination and observation for other reasons
0.775 0.225 0.000
Chapter I Certain infectious and parasitic diseases
0.774 0.226 0.000
D68 Other coagulation defects
0.773 0.227 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.771 0.229 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.771 0.229 0.000
C64-C68 Malignant neoplasms of urinary tract
0.770 0.230 0.000
K22 Other diseases of oesophagus
0.770 0.230 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.768 0.232 0.000
Q60-Q64 Congenital malformations of the urinary system
0.767 0.233 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.767 0.233 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.765 0.235 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.764 0.236 0.000
Z84 Family history of other conditions
0.764 0.236 0.000
D75 Other diseases of blood and blood-forming organs
0.764 0.236 0.000
O80 Single spontaneous delivery
0.762 0.238 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.761 0.239 0.000
C45 Mesothelioma
0.760 0.240 0.000
K72 Hepatic failure, not elsewhere classified
0.760 0.240 0.000
C15.9 Oesophagus, unspecified
0.760 0.240 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.760 0.240 0.000
Z93 Artificial opening status
0.760 0.240 0.000
Y84.8 Other medical procedures
0.759 0.241 0.000
C54.1 Endometrium
0.759 0.241 0.000
S90-S99 Injuries to the ankle and foot
0.757 0.242 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.757 0.243 0.000
D80-D89 Certain disorders involving the immune mechanism
0.756 0.244 0.000
K75 Other inflammatory liver diseases
0.756 0.244 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.755 0.245 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.754 0.246 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.753 0.247 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.752 0.248 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.751 0.248 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.751 0.249 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.750 0.250 0.000
Z51.5 Palliative care
0.750 0.250 0.000
Z42 Follow-up care involving plastic surgery
0.750 0.250 0.000
M80-M85 Disorders of bone density and structure
0.749 0.251 0.000
Z43 Attention to artificial openings
0.749 0.251 0.000
C18.6 Descending colon
0.747 0.253 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.747 0.253 0.000
C18.0 Caecum
0.746 0.254 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.745 0.255 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.744 0.256 0.000
O80.0 Spontaneous vertex delivery
0.743 0.257 0.000
K76 Other diseases of liver
0.742 0.258 0.000
Z52 Donors of organs and tissues
0.741 0.259 0.000
D52 Folate deficiency anaemia
0.741 0.259 0.000
Z53.8 Procedure not carried out for other reasons
0.740 0.260 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.739 0.261 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.737 0.262 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.736 0.264 0.000
E70-E90 Metabolic disorders
0.735 0.265 0.000
K26.0 Acute with haemorrhage
0.732 0.268 0.000
K50-K52 Noninfective enteritis and colitis
0.732 0.268 0.000
D45 Polycythaemia vera
0.731 0.269 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.730 0.270 0.000
M91-M94 Chondropathies
0.730 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.730 0.270 0.000
K26.4 Chronic or unspecified with haemorrhage
0.729 0.271 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.729 0.271 0.000
M24 Other specific joint derangements
0.728 0.272 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.727 0.273 0.000
Z90.8 Acquired absence of other organs
0.727 0.273 0.000
Z97.4 Presence of external hearing-aid
0.726 0.274 0.000
W00-W19 Falls
0.725 0.275 0.000
M23.5 Chronic instability of knee
0.724 0.276 0.000
M86-M90 Other osteopathies
0.723 0.277 0.000
C79.6 Secondary malignant neoplasm of ovary
0.721 0.279 0.000
Y84.2 Radiological procedure and radiotherapy
0.720 0.280 0.000
D70 Agranulocytosis
0.720 0.280 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.720 0.280 0.000
K22.1 Ulcer of oesophagus
0.720 0.280 0.000
K26.7 Chronic without haemorrhage or perforation
0.719 0.281 0.000
D10-D36 Benign neoplasms
0.718 0.282 0.000
T93 Sequelae of injuries of lower limb
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.717 0.283 0.000
K66 Other disorders of peritoneum
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
O70 Perineal laceration during delivery
0.717 0.283 0.000
B35-B49 Mycoses
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
K31.7 Polyp of stomach and duodenum
0.717 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.715 0.285 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.715 0.285 0.000
Z51.9 Medical care, unspecified
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.715 0.285 0.000
D00-D09 In situ neoplasms
0.713 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
Z10 Routine general health check-up of defined subpopulation
0.713 0.287 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.713 0.287 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.713 0.287 0.000
M45 Ankylosing spondylitis
0.713 0.287 0.000
D51 Vitamin B12 deficiency anaemia
0.713 0.287 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.713 0.287 0.000
K92.9 Disease of digestive system, unspecified
0.713 0.287 0.000
K92.8 Other specified diseases of digestive system
0.713 0.287 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.712 0.287 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.712 0.288 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.712 0.288 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.712 0.288 0.000
Z82.2 Family history of deafness and hearing loss
0.712 0.288 0.000
Z82.1 Family history of blindness and visual loss
0.712 0.288 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
T87 Complications peculiar to reattachment and amputation
0.710 0.290 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.710 0.290 0.000
M15 Polyarthrosis
0.709 0.291 0.000
S68 Traumatic amputation of wrist and hand
0.709 0.291 0.000
C34.3 Lower lobe, bronchus or lung
0.709 0.291 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.708 0.292 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.708 0.292 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.708 0.292 0.000
M17.5 Other secondary gonarthrosis
0.707 0.292 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.707 0.292 0.000
M17.3 Other posttraumatic gonarthrosis
0.707 0.292 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.707 0.292 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
C95 Leukaemia of unspecified cell type
0.707 0.293 0.000
C94 Other leukaemias of specified cell type
0.707 0.293 0.000
C93 Monocytic leukaemia
0.707 0.293 0.000
C88 Malignant immunoproliferative diseases
0.707 0.293 0.000
C86 Other specified types of T/NK-cell lymphoma
0.707 0.293 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.707 0.293 0.000
K29 Gastritis and duodenitis
0.706 0.294 0.000
Z36 Antenatal screening
0.706 0.294 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.706 0.294 0.000
M18 Arthrosis of first carpometacarpal joint
0.705 0.295 0.000
D50.9 Iron deficiency anaemia, unspecified
0.705 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.705 0.295 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.705 0.295 0.000
C21 Malignant neoplasm of anus and anal canal
0.705 0.295 0.000
C17 Malignant neoplasm of small intestine
0.705 0.295 0.000
C23 Malignant neoplasm of gallbladder
0.705 0.295 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.704 0.296 0.000
Z90.3 Acquired absence of part of stomach
0.704 0.296 0.000
S64 Injury of nerves at wrist and hand level
0.703 0.297 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.703 0.297 0.000
K27 Peptic ulcer, site unspecified
0.701 0.299 0.000
Z49 Care involving dialysis
0.701 0.299 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.701 0.299 0.000
O00-O08 Pregnancy with abortive outcome
0.700 0.300 0.000
C79.2 Secondary malignant neoplasm of skin
0.700 0.300 0.000
Y84.0 Cardiac catheterisation
0.697 0.303 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.697 0.303 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.696 0.303 0.000
V10-V19 Pedal cyclist injured in transport accident
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.695 0.304 0.000
M34 Systemic sclerosis
0.695 0.304 0.000
M33 Dermatopolymyositis
0.695 0.304 0.000
M32 Systemic lupus erythematosus
0.695 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.695 0.304 0.000
M65-M68 Disorders of synovium and tendon
0.695 0.305 0.000
M35 Other systemic involvement of connective tissue
0.694 0.305 0.000
C92.0 Acute myeloid leukaemia
0.694 0.306 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.693 0.307 0.000
Z97.8 Presence of other specified devices
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
M31.6 Other giant cell arteritis
0.691 0.309 0.000
K29.8 Duodenitis
0.690 0.310 0.000
D69 Purpura and other haemorrhagic conditions
0.689 0.311 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
Y00-Y09 Assault
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.688 0.312 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.688 0.312 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.688 0.312 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.688 0.312 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.688 0.312 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.688 0.312 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.688 0.312 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.688 0.312 0.000
T36 Poisoning by systemic antibiotics
0.688 0.312 0.000
C81 Hodgkin's disease
0.687 0.312 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.686 0.314 0.000
D53 Other nutritional anaemias
0.685 0.315 0.000
M25 Other joint disorders, not elsewhere classified
0.684 0.316 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.684 0.316 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.684 0.316 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.684 0.316 0.000
T82.3 Mechanical complication of other vascular grafts
0.684 0.316 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.684 0.316 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.684 0.316 0.000
C51 Malignant neoplasm of vulva
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.683 0.316 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.683 0.316 0.000
C32 Malignant neoplasm of larynx
0.683 0.316 0.000
C31 Malignant neoplasm of accessory sinuses
0.683 0.316 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.683 0.316 0.000
C37 Malignant neoplasm of thymus
0.683 0.316 0.000
C33 Malignant neoplasm of trachea
0.683 0.316 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.683 0.317 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.683 0.317 0.000
Z51.8 Other specified medical care
0.683 0.317 0.000
K74 Fibrosis and cirrhosis of liver
0.682 0.318 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.682 0.318 0.000
Q80-Q89 Other congenital malformations
0.682 0.318 0.000
C34.0 Main bronchus
0.682 0.318 0.000
C20 Malignant neoplasm of rectum
0.680 0.320 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.678 0.322 0.000
K25 Gastric ulcer
0.678 0.322 0.000
M47 Spondylosis
0.677 0.323 0.000
M46 Other inflammatory spondylopathies
0.676 0.324 0.000
Z92.8 Personal history of other medical treatment
0.676 0.324 0.000
S61 Open wound of wrist and hand
0.674 0.326 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.674 0.326 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.674 0.326 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.674 0.326 0.000
D68.9 Coagulation defect, unspecified
0.674 0.326 0.000
C18.2 Ascending colon
0.673 0.327 0.000
M23.9 Internal derangement of knee, unspecified
0.673 0.327 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.673 0.327 0.000
M23.1 Discoid meniscus (congenital)
0.673 0.327 0.000
M23.0 Cystic meniscus
0.673 0.327 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.672 0.328 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.672 0.328 0.000
C85.0 Lymphosarcoma
0.672 0.328 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.671 0.329 0.000
O70.1 Second degree perineal laceration during delivery
0.670 0.330 0.000
K77 Liver disorders in diseases classified elsewhere
0.670 0.330 0.000
K73 Chronic hepatitis, not elsewhere classified
0.670 0.330 0.000
K71 Toxic liver disease
0.670 0.330 0.000
Z45.1 Adjustment and management of infusion pump
0.670 0.330 0.000
S69 Other and unspecified injuries of wrist and hand
0.669 0.331 0.000
Q50-Q56 Congenital malformations of genital organs
0.669 0.331 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.669 0.331 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.331 0.000
S50-S59 Injuries to the elbow and forearm
0.668 0.332 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.668 0.332 0.000
Chapter X Diseases of the respiratory system
0.667 0.333 0.000
S70-S79 Injuries to the hip and thigh
0.667 0.333 0.000
T40.2 Other opioids
0.667 0.333 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.666 0.334 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.666 0.334 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.665 0.334 0.000
W20-W49 Exposure to inanimate mechanical forces
0.664 0.336 0.000
Z29 Need for other prophylactic measures
0.664 0.336 0.000
Z94.8 Other transplanted organ and tissue status
0.663 0.337 0.000
C18.8 Overlapping lesion of colon
0.663 0.337 0.000
C18.5 Splenic flexure
0.663 0.337 0.000
C18.3 Hepatic flexure
0.663 0.337 0.000
C18.1 Appendix
0.663 0.337 0.000
D41.4 Bladder
0.662 0.338 0.000
O62 Abnormalities of forces of labour
0.662 0.338 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.661 0.339 0.000
D27 Benign neoplasm of ovary
0.660 0.340 0.000
K31.8 Other specified diseases of stomach and duodenum
0.660 0.340 0.000
C34.8 Overlapping lesion of bronchus and lung
0.659 0.340 0.000
C34.2 Middle lobe, bronchus or lung
0.659 0.340 0.000
C15.8 Overlapping lesion of oesophagus
0.658 0.342 0.000
C15.4 Middle third of oesophagus
0.658 0.342 0.000
C15.3 Upper third of oesophagus
0.658 0.342 0.000
C15.2 Abdominal part of oesophagus
0.658 0.342 0.000
C15.1 Thoracic part of oesophagus
0.658 0.342 0.000
C15.0 Cervical part of oesophagus
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.342 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.657 0.342 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.342 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.342 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.342 0.000
Q00-Q07 Congenital malformations of the nervous system
0.657 0.342 0.000
D50.1 Sideropenic dysphagia
0.657 0.343 0.000
C67 Malignant neoplasm of bladder
0.657 0.343 0.000
K76.8 Other specified diseases of liver
0.657 0.343 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.657 0.343 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.657 0.343 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.657 0.343 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.657 0.343 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.657 0.343 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.657 0.343 0.000
D75.1 Secondary polycythaemia
0.657 0.343 0.000
B37 Candidiasis
0.656 0.344 0.000
Z98.8 Other specified postsurgical states
0.656 0.344 0.000
T81.9 Unspecified complication of procedure
0.655 0.344 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.655 0.344 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.655 0.344 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.655 0.344 0.000
D62 Acute posthaemorrhagic anaemia
0.655 0.345 0.000
Z40.9 Prophylactic surgery, unspecified
0.654 0.345 0.000
Z40.8 Other prophylactic surgery
0.654 0.345 0.000
Z33 Pregnant state, incidental
0.654 0.346 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.654 0.346 0.000
T90 Sequelae of injuries of head
0.654 0.346 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.654 0.346 0.000
Z97.3 Presence of spectacles and contact lenses
0.653 0.346 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.653 0.346 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.653 0.346 0.000
Z97.0 Presence of artificial eye
0.653 0.346 0.000
K26.5 Chronic or unspecified with perforation
0.653 0.347 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.652 0.348 0.000
C90.3 Solitary plasmacytoma
0.651 0.349 0.000
C90.2 Plasmacytoma, extramedullary
0.651 0.349 0.000
C90.1 Plasma cell leukaemia
0.651 0.349 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.651 0.349 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.651 0.349 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.651 0.349 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.651 0.349 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.651 0.349 0.000
T83.2 Mechanical complication of graft of urinary organ
0.651 0.349 0.000
K28 Gastrojejunal ulcer
0.651 0.349 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.651 0.349 0.000
Z95.1 Presence of aortocoronary bypass graft
0.651 0.349 0.000
Z09.4 Follow-up examination after treatment of fracture
0.650 0.349 0.000
Z09.3 Follow-up examination after psychotherapy
0.650 0.349 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.650 0.349 0.000
Y95 Nosocomial condition
0.650 0.350 0.000
M19 Other arthrosis
0.650 0.350 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.648 0.352 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.648 0.352 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.648 0.352 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.648 0.352 0.000
C92.1 Chronic myeloid leukaemia
0.648 0.352 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.648 0.352 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.647 0.353 0.000
K70.9 Alcoholic liver disease, unspecified
0.647 0.353 0.000
C44 Other malignant neoplasms of skin
0.646 0.354 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.646 0.354 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.646 0.354 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.646 0.354 0.000
T42.3 Barbiturates
0.646 0.354 0.000
T42.2 Succinimides and oxazolidinediones
0.646 0.354 0.000
T42.1 Iminostilbenes
0.646 0.354 0.000
T42.0 Hydantoin derivatives
0.646 0.354 0.000
M05-M14 Inflammatory polyarthropathies
0.645 0.355 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.645 0.355 0.000
K51 Ulcerative colitis
0.644 0.356 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.644 0.356 0.000
M23.4 Loose body in knee
0.643 0.357 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.643 0.357 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.642 0.358 0.000
Z46.6 Fitting and adjustment of urinary device
0.642 0.358 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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