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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35775808
log Bayes Factor = 0.734475
Chromosome 9   position 102,225,544  (GRCh37) Explore rs35775808 on Ensembl!
Variant rs35775808 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.581 0.419 0.000
G43.9 Migraine, unspecified
0.552 0.448 0.000
G43 Migraine
0.548 0.452 0.000
G40-G47 Episodic and paroxysmal disorders
0.542 0.458 0.000
G47 Sleep disorders
0.524 0.476 0.000
G47.9 Sleep disorder, unspecified
0.499 0.501 0.000
Chapter VI Diseases of the nervous system
0.489 0.511 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.481 0.519 0.000
G44 Other headache syndromes
0.474 0.526 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.451 0.549 0.000
G43.8 Other migraine
0.447 0.553 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.440 0.560 0.000
G41 Status epilepticus
0.428 0.572 0.000
G20-G26 Extrapyramidal and movement disorders
0.426 0.574 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.424 0.576 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.424 0.576 0.000
G43.1 Migraine with aura [classical migraine]
0.423 0.577 0.000
G44.0 Cluster headache syndrome
0.410 0.590 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.400 0.600 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.398 0.602 0.000
G43.3 Complicated migraine
0.393 0.607 0.000
G43.2 Status migrainosus
0.393 0.607 0.000
G43.0 Migraine without aura [common migraine]
0.393 0.607 0.000
G90-G99 Other disorders of the nervous system
0.393 0.607 0.000
G47.8 Other sleep disorders
0.391 0.609 0.000
G03 Meningitis due to other and unspecified causes
0.391 0.609 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.389 0.611 0.000
G47.4 Narcolepsy and cataplexy
0.383 0.617 0.000
G44.8 Other specified headache syndromes
0.382 0.618 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.380 0.620 0.000
G47.2 Disorders of the sleep-wake schedule
0.376 0.624 0.000
G24 Dystonia
0.368 0.632 0.000
G80 Infantile cerebral palsy
0.364 0.636 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.364 0.636 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.357 0.643 0.000
G00 Bacterial meningitis, not elsewhere classified
0.356 0.643 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.351 0.649 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.350 0.650 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.348 0.652 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.346 0.654 0.000
G41.9 Status epilepticus, unspecified
0.346 0.654 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.345 0.655 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.345 0.655 0.000
G93 Other disorders of brain
0.341 0.659 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.340 0.660 0.000
G44.3 Chronic posttraumatic headache
0.340 0.660 0.000
G44.1 Vascular headache, not elsewhere classified
0.340 0.660 0.000
G83 Other paralytic syndromes
0.336 0.664 0.000
G82 Paraplegia and tetraplegia
0.333 0.667 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.327 0.673 0.000
G03.9 Meningitis, unspecified
0.326 0.674 0.000
G44.2 Tension-type headache
0.324 0.675 0.000
G20 Parkinson's disease
0.322 0.678 0.000
G80.9 Infantile cerebral palsy, unspecified
0.322 0.678 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.319 0.681 0.000
G70-G73 Diseases of myoneural junction and muscle
0.316 0.684 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.316 0.684 0.000
G04.1 Tropical spastic paraplegia
0.316 0.684 0.000
G04.0 Acute disseminated encephalitis
0.316 0.684 0.000
G25 Other extrapyramidal and movement disorders
0.315 0.685 0.000
G95 Other diseases of spinal cord
0.311 0.689 0.000
G41.8 Other status epilepticus
0.307 0.693 0.000
G41.2 Complex partial status epilepticus
0.307 0.693 0.000
G41.1 Petit mal status epilepticus
0.307 0.693 0.000
G41.0 Grand mal status epilepticus
0.307 0.693 0.000
G23 Other degenerative diseases of basal ganglia
0.305 0.695 0.000
G21 Secondary Parkinsonism
0.305 0.695 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.305 0.695 0.000
G22 Parkinsonism in diseases classified elsewhere
0.305 0.695 0.000
G93.3 Postviral fatigue syndrome
0.305 0.695 0.000
E03 Other hypothyroidism
0.304 0.696 0.000
G24.9 Dystonia, unspecified
0.302 0.698 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.302 0.698 0.000
G47.3 Sleep apnoea
0.300 0.700 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.296 0.704 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.295 0.705 0.000
G24.8 Other dystonia
0.288 0.712 0.000
G45.4 Transient global amnesia
0.288 0.712 0.000
G93.4 Encephalopathy, unspecified
0.287 0.713 0.000
G93.2 Benign intracranial hypertension
0.285 0.715 0.000
G24.5 Blepharospasm
0.285 0.715 0.000
G92 Toxic encephalopathy
0.282 0.718 0.000
G03.8 Meningitis due to other specified causes
0.280 0.720 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.280 0.720 0.000
G03.1 Chronic meningitis
0.280 0.720 0.000
G03.0 Nonpyogenic meningitis
0.280 0.720 0.000
G83.1 Monoplegia of lower limb
0.280 0.720 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.279 0.721 0.000
G46.7 Other lacunar syndromes
0.279 0.721 0.000
G46.6 Pure sensory lacunar syndrome
0.279 0.721 0.000
G46.5 Pure motor lacunar syndrome
0.279 0.721 0.000
G46.4 Cerebellar stroke syndrome
0.279 0.721 0.000
G46.3 Brain stem stroke syndrome
0.279 0.721 0.000
G46.2 Posterior cerebral artery syndrome
0.279 0.721 0.000
G46.1 Anterior cerebral artery syndrome
0.279 0.721 0.000
G46.0 Middle cerebral artery syndrome
0.279 0.721 0.000
G35 Multiple sclerosis
0.277 0.723 0.000
G96 Other disorders of central nervous system
0.272 0.728 0.000
G90 Disorders of autonomic nervous system
0.269 0.731 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.268 0.731 0.000
G00.9 Bacterial meningitis, unspecified
0.267 0.733 0.000
G24.4 Idiopathic orofacial dystonia
0.264 0.736 0.000
G24.3 Spasmodic torticollis
0.264 0.736 0.000
G24.2 Idiopathic nonfamilial dystonia
0.264 0.736 0.000
G24.1 Idiopathic familial dystonia
0.264 0.736 0.000
G24.0 Drug-induced dystonia
0.264 0.736 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.261 0.738 0.000
G80.8 Other infantile cerebral palsy
0.261 0.739 0.000
G80.4 Ataxic cerebral palsy
0.261 0.739 0.000
G80.3 Dyskinetic cerebral palsy
0.261 0.739 0.000
G80.2 Infantile hemiplegia
0.261 0.739 0.000
G80.1 Spastic diplegia
0.261 0.739 0.000
G80.0 Spastic cerebral palsy
0.261 0.739 0.000
G36 Other acute disseminated demyelination
0.261 0.739 0.000
G61 Inflammatory polyneuropathy
0.261 0.739 0.000
G83.9 Paralytic syndrome, unspecified
0.260 0.740 0.000
G06.1 Intraspinal abscess and granuloma
0.258 0.742 0.000
G37 Other demyelinating diseases of central nervous system
0.257 0.742 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.256 0.744 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.256 0.744 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.256 0.744 0.000
G82.1 Spastic paraplegia
0.256 0.744 0.000
G00.8 Other bacterial meningitis
0.256 0.744 0.000
G00.3 Staphylococcal meningitis
0.256 0.744 0.000
G00.2 Streptococcal meningitis
0.256 0.744 0.000
G00.1 Pneumococcal meningitis
0.256 0.744 0.000
G00.0 Haemophilus meningitis
0.256 0.744 0.000
G30-G32 Other degenerative diseases of the nervous system
0.252 0.748 0.000
G81 Hemiplegia
0.252 0.748 0.000
G06.2 Extradural and subdural abscess, unspecified
0.252 0.748 0.000
G06.0 Intracranial abscess and granuloma
0.252 0.748 0.000
G82.2 Paraplegia, unspecified
0.251 0.749 0.000
G95.8 Other specified diseases of spinal cord
0.249 0.751 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.248 0.752 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.248 0.752 0.000
G45.0 Vertebro-basilar artery syndrome
0.248 0.752 0.000
G25.2 Other specified forms of tremor
0.248 0.752 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.247 0.752 0.000
G02.1 Meningitis in mycoses
0.247 0.752 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.247 0.752 0.000
G93.0 Cerebral cysts
0.247 0.753 0.000
G95.2 Cord compression, unspecified
0.247 0.753 0.000
G93.7 Reye's syndrome
0.245 0.755 0.000
G93.5 Compression of brain
0.245 0.755 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.245 0.755 0.000
G62 Other polyneuropathies
0.243 0.757 0.000
G82.5 Tetraplegia, unspecified
0.243 0.757 0.000
G40 Epilepsy
0.242 0.758 0.000
G83.5 Locked-in syndrome
0.241 0.759 0.000
G83.3 Monoplegia, unspecified
0.241 0.759 0.000
G83.2 Monoplegia of upper limb
0.241 0.759 0.000
G83.0 Diplegia of upper limbs
0.241 0.759 0.000
G93.6 Cerebral oedema
0.240 0.760 0.000
G83.8 Other specified paralytic syndromes
0.239 0.760 0.000
G82.4 Spastic tetraplegia
0.239 0.761 0.000
G82.3 Flaccid tetraplegia
0.239 0.761 0.000
G82.0 Flaccid paraplegia
0.239 0.761 0.000
G93.9 Disorder of brain, unspecified
0.235 0.765 0.000
G72 Other myopathies
0.234 0.765 0.000
G64 Other disorders of peripheral nervous system
0.234 0.765 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.229 0.771 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.228 0.772 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.227 0.773 0.000
G94.1 Hydrocephalus in neoplastic disease
0.226 0.774 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.226 0.774 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.226 0.774 0.000
G25.5 Other chorea
0.226 0.774 0.000
G25.4 Drug-induced chorea
0.226 0.774 0.000
G25.1 Drug-induced tremor
0.226 0.774 0.000
G25.3 Myoclonus
0.225 0.775 0.000
G25.0 Essential tremor
0.224 0.776 0.000
G97.8 Other postprocedural disorders of nervous system
0.223 0.777 0.000
G95.0 Syringomyelia and syringobulbia
0.223 0.777 0.000
G71 Primary disorders of muscles
0.222 0.778 0.000
G95.1 Vascular myelopathies
0.220 0.780 0.000
G21.9 Secondary Parkinsonism, unspecified
0.219 0.781 0.000
G21.8 Other secondary Parkinsonism
0.219 0.781 0.000
G21.4 Vascular parkinsonism
0.219 0.781 0.000
G21.3 Postencephalitic Parkinsonism
0.219 0.781 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.219 0.781 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.219 0.781 0.000
G21.0 Malignant neuroleptic syndrome
0.219 0.781 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.219 0.781 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.219 0.781 0.000
G23.3 Multiple system atrophy, cerebellar type
0.219 0.781 0.000
G23.2 Striatonigral degeneration
0.219 0.781 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.219 0.781 0.000
G23.0 Hallervorden-Spatz disease
0.219 0.781 0.000
G62.8 Other specified polyneuropathies
0.219 0.781 0.000
E03.5 Myxoedema coma
0.218 0.782 0.000
E03.4 Atrophy of thyroid (acquired)
0.218 0.782 0.000
E03.3 Postinfectious hypothyroidism
0.218 0.782 0.000
E03.1 Congenital hypothyroidism without goitre
0.218 0.782 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.218 0.782 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.216 0.784 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.216 0.784 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.213 0.787 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.212 0.787 0.000
G14 Postpolio syndrome
0.212 0.787 0.000
G10 Huntington's disease
0.212 0.787 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.212 0.788 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.212 0.788 0.000
G83.4 Cauda equina syndrome
0.208 0.792 0.000
G61.0 Guillain-Barre syndrome
0.207 0.793 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.204 0.795 0.000
G91 Hydrocephalus
0.204 0.795 0.000
G96.0 Cerebrospinal fluid leak
0.204 0.796 0.000
G90.2 Horner's syndrome
0.203 0.797 0.000
G45.3 Amaurosis fugax
0.203 0.797 0.000
G11 Hereditary ataxia
0.202 0.798 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.200 0.800 0.000
G95.9 Disease of spinal cord, unspecified
0.198 0.802 0.000
G60 Hereditary and idiopathic neuropathy
0.197 0.803 0.000
G96.9 Disorder of central nervous system, unspecified
0.195 0.805 0.000
G96.8 Other specified disorders of central nervous system
0.195 0.805 0.000
G61.8 Other inflammatory polyneuropathies
0.195 0.805 0.000
G90.8 Other disorders of autonomic nervous system
0.193 0.807 0.000
G90.4 Autonomic dysreflexia
0.193 0.807 0.000
G90.3 Multisystem degeneration
0.193 0.807 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.193 0.807 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.193 0.807 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.192 0.808 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.189 0.810 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.189 0.811 0.000
G70 Myasthenia gravis and other myoneural disorders
0.188 0.812 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.188 0.812 0.000
G36.9 Acute disseminated demyelination, unspecified
0.187 0.813 0.000
G36.8 Other specified acute disseminated demyelination
0.187 0.813 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.187 0.813 0.000
G36.0 Neuromyelitis optica [Devic]
0.187 0.813 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.187 0.813 0.000
G61.1 Serum neuropathy
0.187 0.813 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.185 0.815 0.000
G37.5 Concentric sclerosis [Balo]
0.185 0.815 0.000
G37.4 Subacute necrotising myelitis
0.185 0.815 0.000
G37.2 Central pontine myelinolysis
0.185 0.815 0.000
G37.1 Central demyelination of corpus callosum
0.185 0.815 0.000
G37.0 Diffuse sclerosis
0.185 0.815 0.000
E03.8 Other specified hypothyroidism
0.184 0.815 0.000
G40.5 Special epileptic syndromes
0.184 0.816 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.181 0.819 0.000
G81.1 Spastic hemiplegia
0.181 0.819 0.000
G81.0 Flaccid hemiplegia
0.181 0.819 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.178 0.822 0.000
G72.9 Myopathy, unspecified
0.176 0.824 0.000
G62.2 Polyneuropathy due to other toxic agents
0.175 0.825 0.000
G62.1 Alcoholic polyneuropathy
0.175 0.825 0.000
G40.8 Other epilepsy
0.174 0.825 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.174 0.826 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.174 0.826 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.174 0.826 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.173 0.826 0.000
G12 Spinal muscular atrophy and related syndromes
0.173 0.827 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.172 0.828 0.000
G72.8 Other specified myopathies
0.168 0.832 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.168 0.832 0.000
G72.3 Periodic paralysis
0.168 0.832 0.000
G72.2 Myopathy due to other toxic agents
0.168 0.832 0.000
G72.1 Alcoholic myopathy
0.168 0.832 0.000
G72.0 Drug-induced myopathy
0.168 0.832 0.000
G30 Alzheimer's disease
0.167 0.833 0.000
G73.7 Myopathy other diseases classified elsewhere
0.163 0.837 0.000
G73.6 Myopathy in metabolic diseases
0.163 0.837 0.000
G73.5 Myopathy in endocrine diseases
0.163 0.837 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.163 0.837 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.163 0.837 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.163 0.837 0.000
G73.1 Eaton-Lambert syndrome
0.163 0.837 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.163 0.837 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.161 0.839 0.000
G71.1 Myotonic disorders
0.160 0.840 0.000
G71.9 Primary disorder of muscle, unspecified
0.159 0.841 0.000
G71.8 Other primary disorders of muscles
0.159 0.841 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.159 0.841 0.000
G71.2 Congenital myopathies
0.159 0.841 0.000
G93.8 Other specified disorders of brain
0.158 0.842 0.000
G40.9 Epilepsy, unspecified
0.156 0.844 0.000
G62.0 Drug-induced polyneuropathy
0.154 0.846 0.000
G71.0 Muscular dystrophy
0.153 0.847 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.152 0.847 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.152 0.847 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.152 0.847 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.152 0.847 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.148 0.852 0.000
G91.8 Other hydrocephalus
0.147 0.853 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.147 0.853 0.000
G91.2 Normal-pressure hydrocephalus
0.147 0.853 0.000
G91.0 Communicating hydrocephalus
0.147 0.853 0.000
G11.8 Other hereditary ataxias
0.145 0.855 0.000
G11.4 Hereditary spastic paraplegia
0.145 0.855 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.145 0.855 0.000
G11.2 Late-onset cerebellar ataxia
0.145 0.855 0.000
G11.1 Early-onset cerebellar ataxia
0.145 0.855 0.000
G11.0 Congenital nonprogressive ataxia
0.145 0.855 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.143 0.856 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.143 0.856 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.143 0.856 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.143 0.856 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.143 0.856 0.000
G63.1 Polyneuropathy in neoplastic disease
0.143 0.856 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.143 0.856 0.000
H26.9 Cataract, unspecified
0.143 0.857 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.141 0.859 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.141 0.859 0.000
G60.3 Idiopathic progressive neuropathy
0.141 0.859 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.141 0.859 0.000
G60.1 Refsum's disease
0.141 0.859 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.136 0.864 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.136 0.864 0.000
G11.9 Hereditary ataxia, unspecified
0.135 0.865 0.000
G70.9 Myoneural disorder, unspecified
0.135 0.865 0.000
G70.8 Other specified myoneural disorders
0.135 0.865 0.000
G70.2 Congenital and developmental myasthenia
0.135 0.865 0.000
G70.1 Toxic myoneural disorders
0.135 0.865 0.000
G30.0 Alzheimer's disease with early onset
0.130 0.870 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.130 0.870 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.130 0.870 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.130 0.870 0.000
G81.9 Hemiplegia, unspecified
0.129 0.871 0.000
G12.9 Spinal muscular atrophy, unspecified
0.124 0.876 0.000
G12.8 Other spinal muscular atrophies and related syndromes
0.124 0.876 0.000
G12.1 Other inherited spinal muscular atrophy
0.124 0.876 0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.124 0.876 0.000
H26 Other cataract
0.123 0.877 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.121 0.878 0.000
G30.8 Other Alzheimer's disease
0.120 0.880 0.000
G30.1 Alzheimer's disease with late onset
0.120 0.880 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.119 0.881 0.000
G91.1 Obstructive hydrocephalus
0.118 0.882 0.000
G62.9 Polyneuropathy, unspecified
0.116 0.884 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.114 0.885 0.000
G91.9 Hydrocephalus, unspecified
0.114 0.886 0.000
H26.8 Other specified cataract
0.114 0.886 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.111 0.889 0.000
J44 Other chronic obstructive pulmonary disease
0.111 0.889 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.111 0.889 0.000
H26.1 Traumatic cataract
0.109 0.891 0.000
G63.2 Diabetic polyneuropathy
0.109 0.891 0.000
G60.0 Hereditary motor and sensory neuropathy
0.103 0.896 0.001
E00-E07 Disorders of thyroid gland
0.098 0.902 0.000
G70.0 Myasthenia gravis
0.095 0.904 0.001
H25-H28 Disorders of lens
0.092 0.908 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.091 0.909 0.000
H26.3 Drug-induced cataract
0.088 0.912 0.000
G30.9 Alzheimer's disease, unspecified
0.087 0.913 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.086 0.914 0.000
G12.2 Motor neuron disease
0.084 0.915 0.001
H26.0 Infantile, juvenile and presenile cataract
0.083 0.916 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.080 0.920 0.000
J40-J47 Chronic lower respiratory diseases
0.079 0.921 0.000
G31.0 Circumscribed brain atrophy
0.076 0.924 0.000
G31.2 Degeneration of nervous system due to alcohol
0.076 0.924 0.000
G50 Disorders of trigeminal nerve
0.073 0.927 0.000
H26.2 Complicated cataract
0.072 0.927 0.000
H25.1 Senile nuclear cataract
0.072 0.928 0.000
H25 Senile cataract
0.072 0.928 0.000
E06 Thyroiditis
0.072 0.928 0.000
J47 Bronchiectasis
0.072 0.928 0.000
G31.8 Other specified degenerative diseases of nervous system
0.071 0.929 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.070 0.929 0.000
E00 Congenital iodine-deficiency syndrome
0.070 0.929 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.070 0.929 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.070 0.930 0.000
G58 Other mononeuropathies
0.069 0.930 0.000
Chapter VII Diseases of the eye and adnexa
0.067 0.933 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.067 0.933 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.067 0.933 0.000
H43 Disorders of vitreous body
0.067 0.933 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.066 0.934 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.066 0.934 0.000
H43-H45 Disorders of vitreous body and globe
0.066 0.934 0.000
G52 Disorders of other cranial nerves
0.065 0.935 0.000
H43.1 Vitreous haemorrhage
0.065 0.935 0.000
# Top node
0.065 0.935 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.064 0.936 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.064 0.936 0.000
E07 Other disorders of thyroid
0.063 0.937 0.000
H27 Other disorders of lens
0.063 0.937 0.000
J42 Unspecified chronic bronchitis
0.062 0.938 0.000
J43 Emphysema
0.061 0.939 0.000
G58.8 Other specified mononeuropathies
0.061 0.939 0.000
G50.0 Trigeminal neuralgia
0.060 0.940 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.059 0.941 0.000
J46 Status asthmaticus
0.059 0.941 0.000
Q28 Other congenital malformations of circulatory system
0.058 0.942 0.000
Q27 Other congenital malformations of peripheral vascular system
0.058 0.942 0.000
Q80-Q89 Other congenital malformations
0.058 0.942 0.000
J41 Simple and mucopurulent chronic bronchitis
0.057 0.943 0.000
C64-C68 Malignant neoplasms of urinary tract
0.056 0.944 0.000
Chapter II Neoplasms
0.056 0.944 0.000
Chapter XX External causes of morbidity and mortality
0.056 0.944 0.000
E06.3 Autoimmune thyroiditis
0.056 0.944 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.056 0.944 0.000
G51 Facial nerve disorders
0.055 0.944 0.000
G54 Nerve root and plexus disorders
0.055 0.944 0.000
D73.0 Hyposplenism
0.055 0.945 0.000
H43.2 Crystalline deposits in vitreous body
0.055 0.945 0.000
Q21 Congenital malformations of cardiac septa
0.055 0.945 0.000
D73 Diseases of spleen
0.055 0.945 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.054 0.946 0.000
H43.9 Disorder of vitreous body, unspecified
0.054 0.946 0.000
H43.3 Other vitreous opacities
0.054 0.946 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.054 0.946 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.053 0.946 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.053 0.947 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.053 0.947 0.000
Q50-Q56 Congenital malformations of genital organs
0.053 0.947 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.053 0.947 0.000
Q27.3 Peripheral arteriovenous malformation
0.053 0.947 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.052 0.947 0.000
G50.8 Other disorders of trigeminal nerve
0.052 0.947 0.000
G50.1 Atypical facial pain
0.052 0.947 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.053 0.947 0.000
C43 Malignant melanoma of skin
0.052 0.948 0.000
D72 Other disorders of white blood cells
0.052 0.948 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.052 0.948 0.000
H25.2 Senile cataract, morgagnian type
0.052 0.948 0.000
E06.5 Other chronic thyroiditis
0.052 0.948 0.000
E06.4 Drug-induced thyroiditis
0.052 0.948 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.052 0.948 0.000
E06.1 Subacute thyroiditis
0.052 0.948 0.000
E06.0 Acute thyroiditis
0.052 0.948 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.051 0.949 0.000
Q23 Congenital malformations of aortic and mitral valves
0.051 0.949 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.051 0.949 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.051 0.949 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.051 0.949 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.051 0.949 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.051 0.949 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.051 0.949 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.051 0.949 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.051 0.949 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.051 0.949 0.000
W20-W49 Exposure to inanimate mechanical forces
0.051 0.949 0.000
Chapter X Diseases of the respiratory system
0.051 0.949 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.050 0.949 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.050 0.950 0.000
Q25 Congenital malformations of great arteries
0.050 0.950 0.000
G59.0 Diabetic mononeuropathy
0.050 0.950 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.050 0.950 0.000
G58.7 Mononeuritis multiplex
0.050 0.950 0.000
G58.0 Intercostal neuropathy
0.050 0.950 0.000
D72.8 Other specified disorders of white blood cells
0.050 0.950 0.000
E65-E68 Obesity and other hyperalimentation
0.049 0.951 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.048 0.951 0.000
V20-V29 Motorcycle rider injured in transport accident
0.049 0.951 0.000
H43.8 Other disorders of vitreous body
0.049 0.951 0.000
E06.9 Thyroiditis, unspecified
0.048 0.951 0.000
C67 Malignant neoplasm of bladder
0.049 0.951 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.048 0.951 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.048 0.952 0.000
Q35-Q37 Cleft lip and cleft palate
0.048 0.952 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.048 0.952 0.000
C43.5 Malignant melanoma of trunk
0.048 0.952 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.048 0.952 0.000
H43.0 Vitreous prolapse
0.048 0.952 0.000
C65 Malignant neoplasm of renal pelvis
0.048 0.952 0.000
Q85 Phakomatoses, not elsewhere classified
0.048 0.952 0.000
E07.8 Other specified disorders of thyroid
0.048 0.952 0.000
H28.8 Other disorders of lens in diseases classified elsewhere
0.048 0.952 0.000
H28.2 Cataract in other diseases classified elsewhere
0.048 0.952 0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases
0.048 0.952 0.000
H28.0 Diabetic cataract
0.048 0.952 0.000
Q26 Congenital malformations of great veins
0.048 0.952 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.048 0.952 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.048 0.952 0.000
Q21.0 Ventricular septal defect
0.047 0.952 0.000
G51.3 Clonic hemifacial spasm
0.047 0.953 0.000
D75 Other diseases of blood and blood-forming organs
0.047 0.953 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.047 0.953 0.000
G52.9 Cranial nerve disorder, unspecified
0.047 0.953 0.000
G52.8 Disorders of other specified cranial nerves
0.047 0.953 0.000
G52.7 Disorders of multiple cranial nerves
0.047 0.953 0.000
G52.3 Disorders of hypoglossal nerve
0.047 0.953 0.000
G52.2 Disorders of vagus nerve
0.047 0.953 0.000
G52.1 Disorders of glossopharyngeal nerve
0.047 0.953 0.000
G52.0 Disorders of olfactory nerve
0.047 0.953 0.000
Q24 Other congenital malformations of heart
0.047 0.953 0.000
J43.9 Emphysema, unspecified
0.047 0.953 0.000
W75-W84 Other accidental threats to breathing
0.047 0.953 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.046 0.953 0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere
0.046 0.954 0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease
0.046 0.954 0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis
0.046 0.954 0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere
0.046 0.954 0.000
H55-H59 Other disorders of eye and adnexa
0.046 0.954 0.000
Q00-Q07 Congenital malformations of the nervous system
0.046 0.954 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.046 0.954 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.046 0.954 0.000
J43.2 Centrilobular emphysema
0.046 0.954 0.000
E07.1 Dyshormogenetic goitre
0.045 0.954 0.000
E07.0 Hypersecretion of calcitonin
0.045 0.954 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.046 0.954 0.000
V70-V79 Bus occupant injured in transport accident
0.045 0.955 0.000
G53.0 Postzoster neuralgia
0.045 0.955 0.000
H27.9 Disorder of lens, unspecified
0.045 0.955 0.000
Q83 Congenital malformations of breast
0.045 0.955 0.000
Q89 Other congenital malformations, not elsewhere classified
0.045 0.955 0.000
Q12 Congenital lens malformations
0.045 0.955 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.045 0.955 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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