TreeWAS – Variant ID: rs35814746

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
G35 Multiple sclerosis	0.999	0.001	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.996	0.004	0.000
Chapter VI Diseases of the nervous system	0.992	0.008	0.000
G40-G47 Episodic and paroxysmal disorders	0.968	0.032	0.000
G20-G26 Extrapyramidal and movement disorders	0.963	0.037	0.000
G40 Epilepsy	0.945	0.055	0.000
G30-G32 Other degenerative diseases of the nervous system	0.942	0.058	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.904	0.096	0.000
G47 Sleep disorders	0.889	0.111	0.000
G90-G99 Other disorders of the nervous system	0.882	0.118	0.000
G25 Other extrapyramidal and movement disorders	0.876	0.124	0.000
G47.9 Sleep disorder, unspecified	0.872	0.128	0.000
G24 Dystonia	0.862	0.138	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.849	0.151	0.000
G95 Other diseases of spinal cord	0.842	0.158	0.000
G30 Alzheimer's disease	0.837	0.163	0.000
G37 Other demyelinating diseases of central nervous system	0.824	0.176	0.000
G44 Other headache syndromes	0.812	0.188	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.807	0.193	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.797	0.203	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.797	0.203	0.000
G20 Parkinson's disease	0.779	0.221	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.764	0.236	0.000
G95.2 Cord compression, unspecified	0.763	0.237	0.000
G95.0 Syringomyelia and syringobulbia	0.763	0.237	0.000
G31.2 Degeneration of nervous system due to alcohol	0.755	0.245	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.752	0.248	0.000
G40.9 Epilepsy, unspecified	0.750	0.250	0.000
G91 Hydrocephalus	0.749	0.251	0.000
G70-G73 Diseases of myoneural junction and muscle	0.742	0.258	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.730	0.270	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.725	0.275	0.000
G47.2 Disorders of the sleep-wake schedule	0.720	0.280	0.000
G36 Other acute disseminated demyelination	0.714	0.286	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.706	0.294	0.000
G25.0 Essential tremor	0.704	0.296	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.692	0.308	0.000
G95.8 Other specified diseases of spinal cord	0.692	0.308	0.000
G24.3 Spasmodic torticollis	0.692	0.308	0.000
G30.9 Alzheimer's disease, unspecified	0.690	0.309	0.000
G23 Other degenerative diseases of basal ganglia	0.690	0.310	0.000
G21 Secondary Parkinsonism	0.690	0.310	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.690	0.310	0.000
G22 Parkinsonism in diseases classified elsewhere	0.690	0.310	0.000
G41 Status epilepticus	0.690	0.310	0.000
G24.8 Other dystonia	0.688	0.312	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.687	0.313	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.679	0.320	0.000
G44.2 Tension-type headache	0.679	0.321	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.677	0.323	0.000
G24.5 Blepharospasm	0.676	0.324	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.675	0.325	0.000
G24.9 Dystonia, unspecified	0.671	0.329	0.000
G30.8 Other Alzheimer's disease	0.668	0.332	0.000
G30.0 Alzheimer's disease with early onset	0.667	0.333	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.659	0.341	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.658	0.342	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.645	0.354	0.000
G91.1 Obstructive hydrocephalus	0.642	0.358	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.633	0.367	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.633	0.367	0.000
G92 Toxic encephalopathy	0.633	0.367	0.000
K70 Alcoholic liver disease	0.631	0.369	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.630	0.370	0.000
G47.8 Other sleep disorders	0.629	0.371	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.628	0.372	0.000
G25.5 Other chorea	0.628	0.372	0.000
G25.4 Drug-induced chorea	0.628	0.372	0.000
G25.2 Other specified forms of tremor	0.628	0.372	0.000
G25.1 Drug-induced tremor	0.628	0.372	0.000
G44.8 Other specified headache syndromes	0.628	0.372	0.000
K70-K77 Diseases of liver	0.628	0.372	0.000
G24.4 Idiopathic orofacial dystonia	0.618	0.382	0.000
G24.2 Idiopathic nonfamilial dystonia	0.618	0.382	0.000
G24.1 Idiopathic familial dystonia	0.618	0.382	0.000
G24.0 Drug-induced dystonia	0.618	0.382	0.000
K76 Other diseases of liver	0.617	0.383	0.000
K74 Fibrosis and cirrhosis of liver	0.615	0.385	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.609	0.391	0.000
G40.5 Special epileptic syndromes	0.604	0.396	0.000
K76.6 Portal hypertension	0.602	0.398	0.000
G40.8 Other epilepsy	0.602	0.398	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.600	0.400	0.000
G30.1 Alzheimer's disease with late onset	0.600	0.400	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.599	0.401	0.000
G46.7 Other lacunar syndromes	0.597	0.403	0.000
G47.4 Narcolepsy and cataplexy	0.594	0.406	0.000
G37.5 Concentric sclerosis [Balo]	0.591	0.409	0.000
G37.4 Subacute necrotising myelitis	0.591	0.409	0.000
G37.2 Central pontine myelinolysis	0.591	0.409	0.000
G37.1 Central demyelination of corpus callosum	0.591	0.409	0.000
G37.0 Diffuse sclerosis	0.591	0.409	0.000
K70.3 Alcoholic cirrhosis of liver	0.591	0.409	0.000
G96 Other disorders of central nervous system	0.589	0.411	0.000
G11 Hereditary ataxia	0.589	0.411	0.000
G31.8 Other specified degenerative diseases of nervous system	0.588	0.412	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.586	0.413	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.582	0.418	0.000
G44.3 Chronic posttraumatic headache	0.582	0.418	0.000
G44.1 Vascular headache, not elsewhere classified	0.582	0.418	0.000
G25.3 Myoclonus	0.579	0.421	0.000
G95.1 Vascular myelopathies	0.576	0.424	0.000
K70.4 Alcoholic hepatic failure	0.574	0.426	0.000
K74.0 Hepatic fibrosis	0.574	0.426	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.571	0.429	0.000
G44.0 Cluster headache syndrome	0.571	0.429	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.570	0.430	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.568	0.432	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.565	0.435	0.000
K70.0 Alcoholic fatty liver	0.564	0.436	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.563	0.437	0.000
G91.9 Hydrocephalus, unspecified	0.561	0.439	0.000
G71 Primary disorders of muscles	0.551	0.449	0.000
G83 Other paralytic syndromes	0.549	0.450	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.548	0.452	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.548	0.452	0.000
G31.0 Circumscribed brain atrophy	0.547	0.453	0.000
K74.6 Other and unspecified cirrhosis of liver	0.547	0.453	0.000
G00 Bacterial meningitis, not elsewhere classified	0.547	0.453	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.543	0.457	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.541	0.459	0.000
G97.8 Other postprocedural disorders of nervous system	0.541	0.459	0.000
G72 Other myopathies	0.541	0.459	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.539	0.461	0.000
G46.6 Pure sensory lacunar syndrome	0.539	0.461	0.000
G46.5 Pure motor lacunar syndrome	0.539	0.461	0.000
G46.4 Cerebellar stroke syndrome	0.539	0.461	0.000
G46.3 Brain stem stroke syndrome	0.539	0.461	0.000
G46.2 Posterior cerebral artery syndrome	0.539	0.461	0.000
G46.1 Anterior cerebral artery syndrome	0.539	0.461	0.000
G46.0 Middle cerebral artery syndrome	0.539	0.461	0.000
G91.8 Other hydrocephalus	0.537	0.463	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.537	0.463	0.000
G91.2 Normal-pressure hydrocephalus	0.537	0.463	0.000
G91.0 Communicating hydrocephalus	0.537	0.463	0.000
G70 Myasthenia gravis and other myoneural disorders	0.536	0.464	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.532	0.468	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.525	0.475	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.523	0.477	0.000
G36.9 Acute disseminated demyelination, unspecified	0.512	0.488	0.000
G36.8 Other specified acute disseminated demyelination	0.512	0.488	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.512	0.488	0.000
G36.0 Neuromyelitis optica [Devic]	0.512	0.488	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.506	0.494	0.000
G14 Postpolio syndrome	0.506	0.494	0.000
G10 Huntington's disease	0.506	0.494	0.000
G41.0 Grand mal status epilepticus	0.503	0.496	0.000
K70.1 Alcoholic hepatitis	0.499	0.501	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.496	0.503	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.496	0.503	0.000
G82 Paraplegia and tetraplegia	0.496	0.504	0.000
G21.9 Secondary Parkinsonism, unspecified	0.495	0.505	0.000
G21.8 Other secondary Parkinsonism	0.495	0.505	0.000
G21.4 Vascular parkinsonism	0.495	0.505	0.000
G21.3 Postencephalitic Parkinsonism	0.495	0.505	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.495	0.505	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.495	0.505	0.000
G21.0 Malignant neuroleptic syndrome	0.495	0.505	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.495	0.505	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.495	0.505	0.000
G23.3 Multiple system atrophy, cerebellar type	0.495	0.505	0.000
G23.2 Striatonigral degeneration	0.495	0.505	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.495	0.505	0.000
G23.0 Hallervorden-Spatz disease	0.495	0.505	0.000
G41.8 Other status epilepticus	0.494	0.505	0.000
G41.2 Complex partial status epilepticus	0.494	0.505	0.000
G41.1 Petit mal status epilepticus	0.494	0.505	0.000
G03 Meningitis due to other and unspecified causes	0.494	0.506	0.000
E83 Disorders of mineral metabolism	0.493	0.507	0.000
G11.4 Hereditary spastic paraplegia	0.489	0.511	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.487	0.513	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.484	0.516	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.484	0.516	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.483	0.517	0.000
G41.9 Status epilepticus, unspecified	0.481	0.519	0.000
K74.3 Primary biliary cirrhosis	0.480	0.520	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.480	0.520	0.000
K76.7 Hepatorenal syndrome	0.480	0.520	0.000
G90 Disorders of autonomic nervous system	0.477	0.523	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.476	0.524	0.000
G06.2 Extradural and subdural abscess, unspecified	0.475	0.525	0.000
K74.5 Biliary cirrhosis, unspecified	0.473	0.527	0.000
G95.9 Disease of spinal cord, unspecified	0.469	0.530	0.000
L40 Psoriasis	0.011	0.537	0.452
L40.5 Arthropathic psoriasis	0.001	0.543	0.456
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.454	0.546	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.454	0.546	0.000
G94.1 Hydrocephalus in neoplastic disease	0.454	0.546	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.454	0.546	0.000
L40.9 Psoriasis, unspecified	0.000	0.547	0.453
K77 Liver disorders in diseases classified elsewhere	0.450	0.550	0.000
K71 Toxic liver disease	0.450	0.550	0.000
G43 Migraine	0.450	0.550	0.000
G11.9 Hereditary ataxia, unspecified	0.448	0.552	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.442	0.557	0.000
K76.5 Hepatic veno-occlusive disease	0.442	0.558	0.000
K76.4 Peliosis hepatis	0.442	0.558	0.000
K76.3 Infarction of liver	0.442	0.558	0.000
K76.2 Central haemorrhagic necrosis of liver	0.442	0.558	0.000
K76.1 Chronic passive congestion of liver	0.442	0.558	0.000
K74.4 Secondary biliary cirrhosis	0.441	0.559	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.441	0.559	0.000
K74.1 Hepatic sclerosis	0.441	0.559	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.430	0.569	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.430	0.569	0.000
G04.1 Tropical spastic paraplegia	0.430	0.569	0.000
G04.0 Acute disseminated encephalitis	0.430	0.569	0.000
G06.1 Intraspinal abscess and granuloma	0.430	0.570	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.429	0.571	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.429	0.571	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.429	0.571	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.428	0.572	0.000
E70-E90 Metabolic disorders	0.427	0.573	0.000
# Top node	0.425	0.575	0.000
Chapter V Mental and behavioural disorders	0.425	0.575	0.000
G96.9 Disorder of central nervous system, unspecified	0.422	0.577	0.000
G96.8 Other specified disorders of central nervous system	0.422	0.577	0.000
G93 Other disorders of brain	0.422	0.578	0.000
G11.8 Other hereditary ataxias	0.422	0.578	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.422	0.578	0.000
G11.2 Late-onset cerebellar ataxia	0.422	0.578	0.000
G11.1 Early-onset cerebellar ataxia	0.422	0.578	0.000
G11.0 Congenital nonprogressive ataxia	0.422	0.578	0.000
G83.9 Paralytic syndrome, unspecified	0.421	0.579	0.000
G83.2 Monoplegia of upper limb	0.421	0.579	0.000
G71.0 Muscular dystrophy	0.420	0.580	0.000
G83.8 Other specified paralytic syndromes	0.419	0.581	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.417	0.583	0.000
G83.4 Cauda equina syndrome	0.417	0.583	0.000
K72 Hepatic failure, not elsewhere classified	0.415	0.585	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.414	0.586	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.414	0.586	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.407	0.592	0.000
Chapter XX External causes of morbidity and mortality	0.405	0.595	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.404	0.596	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.404	0.596	0.000
Chapter XI Diseases of the digestive system	0.403	0.597	0.000
G00.1 Pneumococcal meningitis	0.403	0.597	0.000
G70.9 Myoneural disorder, unspecified	0.401	0.599	0.000
K73 Chronic hepatitis, not elsewhere classified	0.401	0.599	0.000
K70.9 Alcoholic liver disease, unspecified	0.400	0.600	0.000
G72.9 Myopathy, unspecified	0.396	0.604	0.000
G71.9 Primary disorder of muscle, unspecified	0.395	0.604	0.000
G71.8 Other primary disorders of muscles	0.395	0.604	0.000
G71.2 Congenital myopathies	0.395	0.604	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.395	0.605	0.000
G83.5 Locked-in syndrome	0.394	0.606	0.000
G83.3 Monoplegia, unspecified	0.394	0.606	0.000
G83.0 Diplegia of upper limbs	0.394	0.606	0.000
G82.1 Spastic paraplegia	0.394	0.606	0.000
W00-W19 Falls	0.394	0.606	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.393	0.607	0.000
G02.1 Meningitis in mycoses	0.393	0.607	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.393	0.607	0.000
G00.8 Other bacterial meningitis	0.392	0.608	0.000
G00.3 Staphylococcal meningitis	0.392	0.608	0.000
G00.2 Streptococcal meningitis	0.392	0.608	0.000
G00.0 Haemophilus meningitis	0.392	0.608	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.390	0.610	0.000
G83.1 Monoplegia of lower limb	0.389	0.610	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.388	0.612	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.388	0.612	0.000
G72.8 Other specified myopathies	0.388	0.612	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.388	0.612	0.000
G72.3 Periodic paralysis	0.388	0.612	0.000
G72.2 Myopathy due to other toxic agents	0.388	0.612	0.000
G72.1 Alcoholic myopathy	0.388	0.612	0.000
G72.0 Drug-induced myopathy	0.388	0.612	0.000
V40-V49 Car occupant injured in transport accident	0.386	0.614	0.000
G06.0 Intracranial abscess and granuloma	0.386	0.614	0.000
L40.0 Psoriasis vulgaris	0.005	0.615	0.380
F00-F09 Organic, including symptomatic, mental disorders	0.385	0.615	0.000
G70.8 Other specified myoneural disorders	0.384	0.616	0.000
G70.2 Congenital and developmental myasthenia	0.384	0.616	0.000
G70.1 Toxic myoneural disorders	0.384	0.616	0.000
G73.7 Myopathy other diseases classified elsewhere	0.381	0.618	0.000
G73.6 Myopathy in metabolic diseases	0.381	0.618	0.000
G73.5 Myopathy in endocrine diseases	0.381	0.618	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.381	0.618	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.381	0.618	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.381	0.618	0.000
G73.1 Eaton-Lambert syndrome	0.381	0.618	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.381	0.618	0.000
G80 Infantile cerebral palsy	0.380	0.620	0.000
E89.2 Postprocedural hypoparathyroidism	0.380	0.620	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.380	0.620	0.000
G00.9 Bacterial meningitis, unspecified	0.379	0.621	0.000
F10.0 Acute intoxication	0.378	0.622	0.000
L03.1 Cellulitis of other parts of limb	0.378	0.622	0.000
G93.4 Encephalopathy, unspecified	0.375	0.625	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.375	0.625	0.000
F10.2 Dependence syndrome	0.372	0.628	0.000
L20-L30 Dermatitis and eczema	0.371	0.629	0.000
E89.0 Postprocedural hypothyroidism	0.370	0.630	0.000
G70.0 Myasthenia gravis	0.370	0.630	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.369	0.631	0.000
Q80-Q89 Other congenital malformations	0.368	0.632	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.367	0.633	0.000
K40 Inguinal hernia	0.365	0.635	0.000
K40-K46 Hernia	0.365	0.635	0.000
L03 Cellulitis	0.363	0.637	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.363	0.637	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.363	0.637	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.363	0.637	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.363	0.637	0.000
G82.4 Spastic tetraplegia	0.361	0.639	0.000
K76.9 Liver disease, unspecified	0.359	0.641	0.000
E83.3 Disorders of phosphorus metabolism	0.359	0.641	0.000
F99-F99 Unspecified mental disorder	0.359	0.641	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.358	0.642	0.000
G12 Spinal muscular atrophy and related syndromes	0.356	0.643	0.001
F10.1 Harmful use	0.356	0.644	0.000
F60-F69 Disorders of adult personality and behaviour	0.356	0.644	0.000
G82.3 Flaccid tetraplegia	0.355	0.644	0.000
G82.0 Flaccid paraplegia	0.355	0.644	0.000
G03.8 Meningitis due to other specified causes	0.354	0.646	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.354	0.646	0.000
G03.1 Chronic meningitis	0.354	0.646	0.000
G03.0 Nonpyogenic meningitis	0.354	0.646	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.353	0.646	0.000
E83.8 Other disorders of mineral metabolism	0.353	0.646	0.000
E83.2 Disorders of zinc metabolism	0.353	0.646	0.000
E83.0 Disorders of copper metabolism	0.353	0.646	0.000
F10.5 Psychotic disorder	0.350	0.650	0.000
G96.0 Cerebrospinal fluid leak	0.350	0.650	0.000
Q23 Congenital malformations of aortic and mitral valves	0.347	0.653	0.000
G71.1 Myotonic disorders	0.347	0.653	0.000
G81 Hemiplegia	0.347	0.653	0.000
G82.5 Tetraplegia, unspecified	0.345	0.655	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.344	0.656	0.000
L40-L45 Papulosquamous disorders	0.252	0.656	0.092
W18 Other fall on same level	0.343	0.657	0.000
G90.8 Other disorders of autonomic nervous system	0.342	0.658	0.000
G90.4 Autonomic dysreflexia	0.342	0.658	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.342	0.658	0.000
Q25 Congenital malformations of great arteries	0.340	0.660	0.000
G82.2 Paraplegia, unspecified	0.339	0.660	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.339	0.661	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.339	0.661	0.000
K41 Femoral hernia	0.338	0.662	0.000
V10-V19 Pedal cyclist injured in transport accident	0.336	0.663	0.000
V80-V89 Other land transport accidents	0.335	0.665	0.000
E80.1 Porphyria cutanea tarda	0.332	0.668	0.000
L40.8 Other psoriasis	0.008	0.668	0.324
L40.4 Guttate psoriasis	0.008	0.668	0.324
L40.3 Pustulosis palmaris et plantaris	0.008	0.668	0.324
L40.2 Acrodermatitis continua	0.008	0.668	0.324
L40.1 Generalised pustular psoriasis	0.008	0.668	0.324
G90.3 Multisystem degeneration	0.332	0.668	0.000
F11 Mental and behavioural disorders due to use of opioids	0.331	0.668	0.000
Q27 Other congenital malformations of peripheral vascular system	0.329	0.671	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.328	0.672	0.000
L50-L54 Urticaria and erythema	0.327	0.673	0.000
W06 Fall involving bed	0.324	0.676	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.324	0.676	0.000
F80-F89 Disorders of psychological development	0.323	0.677	0.000
K71.9 Toxic liver disease, unspecified	0.323	0.677	0.000
K71.8 Toxic liver disease with other disorders of liver	0.323	0.677	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.323	0.677	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.323	0.677	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.323	0.677	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.323	0.677	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.323	0.677	0.000
K71.2 Toxic liver disease with acute hepatitis	0.323	0.677	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.323	0.677	0.000
K71.0 Toxic liver disease with cholestasis	0.323	0.677	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.323	0.677	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.323	0.677	0.000
G43.3 Complicated migraine	0.322	0.677	0.000
G43.2 Status migrainosus	0.322	0.677	0.000
G43.0 Migraine without aura [common migraine]	0.322	0.677	0.000
E00-E07 Disorders of thyroid gland	0.322	0.678	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.322	0.678	0.000
Chapter XXII Codes for special purposes	0.322	0.678	0.000
Q89 Other congenital malformations, not elsewhere classified	0.321	0.679	0.000
Q24 Other congenital malformations of heart	0.320	0.680	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.319	0.681	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.319	0.681	0.000
F70-F79 Mental retardation	0.319	0.681	0.000
W17 Other fall from one level to another	0.318	0.682	0.000
X50-X57 Overexertion, travel and privation	0.316	0.684	0.000
I83 Varicose veins of lower extremities	0.316	0.684	0.000
G43.8 Other migraine	0.315	0.685	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.314	0.686	0.000
W19 Unspecified fall	0.314	0.686	0.000
L30 Other dermatitis	0.313	0.687	0.000
F10.4 Withdrawal state with delirium	0.312	0.687	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.312	0.688	0.000
K50-K52 Noninfective enteritis and colitis	0.312	0.688	0.000
W50-W64 Exposure to animate mechanical forces	0.312	0.688	0.000
F99 Mental disorder, not otherwise specified	0.312	0.688	0.000
Q00-Q07 Congenital malformations of the nervous system	0.312	0.688	0.000
X00-X09 Exposure to smoke, fire and flames	0.311	0.689	0.000
K76.8 Other specified diseases of liver	0.311	0.689	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.311	0.689	0.000
F10.6 Amnesic syndrome	0.311	0.689	0.000
V70-V79 Bus occupant injured in transport accident	0.310	0.690	0.000
F00 Dementia in Alzheimer's disease	0.309	0.691	0.000
Q23.1 Congenital insufficiency of aortic valve	0.309	0.691	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.308	0.692	0.000
G93.0 Cerebral cysts	0.308	0.692	0.000
L28 Lichen simplex chronicus and prurigo	0.307	0.693	0.000
L20 Atopic dermatitis	0.307	0.693	0.000
E84 Cystic fibrosis	0.306	0.694	0.000
E79 Disorders of purine and pyrimidine metabolism	0.306	0.694	0.000
E77 Disorders of glycoprotein metabolism	0.306	0.694	0.000
E76 Disorders of glycosaminoglycan metabolism	0.306	0.694	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.306	0.694	0.000
E72 Other disorders of amino-acid metabolism	0.306	0.694	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.306	0.694	0.000
E70 Disorders of aromatic amino-acid metabolism	0.306	0.694	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.306	0.694	0.000
Q82 Other congenital malformations of skin	0.305	0.695	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.305	0.695	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.305	0.695	0.000
E04 Other non-toxic goitre	0.305	0.695	0.000
Y00-Y09 Assault	0.304	0.696	0.000
K51 Ulcerative colitis	0.304	0.696	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.304	0.696	0.000
W08 Fall involving other furniture	0.303	0.697	0.000
G93.7 Reye's syndrome	0.303	0.697	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.301	0.699	0.000
G93.5 Compression of brain	0.301	0.699	0.000
V43 Car occupant injured in collision with car, pick-up truck or van	0.300	0.700	0.000
G03.9 Meningitis, unspecified	0.299	0.700	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.299	0.701	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.299	0.701	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.299	0.701	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.299	0.701	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.299	0.701	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.299	0.701	0.000
K72.1 Chronic hepatic failure	0.298	0.702	0.000
W10 Fall on and from stairs and steps	0.298	0.702	0.000
F01 Vascular dementia	0.297	0.703	0.000
F10.8 Other mental and behavioural disorders	0.297	0.703	0.000
F10.7 Residual and late-onset psychotic disorder	0.297	0.703	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.297	0.703	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.297	0.703	0.000
E89.5 Postprocedural testicular hypofunction	0.297	0.703	0.000
E89.4 Postprocedural ovarian failure	0.297	0.703	0.000
E89.1 Postprocedural hypoinsulinaemia	0.297	0.703	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.295	0.705	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.295	0.705	0.000
X10-X19 Contact with heat and hot substances	0.295	0.705	0.000
L03.2 Cellulitis of face	0.294	0.706	0.000
V48 Car occupant injured in noncollision transport accident	0.293	0.707	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.293	0.707	0.000
W18.3 Sports and athletics area	0.292	0.708	0.000
L29 Pruritus	0.292	0.708	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.292	0.708	0.000
E04.2 Non-toxic multinodular goitre	0.292	0.708	0.000
E89.3 Postprocedural hypopituitarism	0.291	0.709	0.000
Y35-Y36 Legal intervention and operations of war	0.291	0.709	0.000
Y10-Y34 Event of undetermined intent	0.291	0.709	0.000
X85-X99 Assault	0.291	0.709	0.000
X30-X39 Exposure to forces of nature	0.291	0.709	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.291	0.709	0.000
W75-W84 Other accidental threats to breathing	0.291	0.709	0.000
W65-W74 Accidental drowning and submersion	0.291	0.709	0.000
V98-V99 Other and unspecified transport accidents	0.291	0.709	0.000
V95-V97 Air and space transport accidents	0.291	0.709	0.000
V90-V94 Water transport accidents	0.291	0.709	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.291	0.709	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.291	0.709	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.291	0.709	0.000
V01-V09 Pedestrian injured in transport accident	0.291	0.709	0.000
K72.9 Hepatic failure, unspecified	0.291	0.709	0.000
Q35-Q37 Cleft lip and cleft palate	0.290	0.710	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.290	0.710	0.000
Chapter IX Diseases of the circulatory system	0.290	0.710	0.000
G93.8 Other specified disorders of brain	0.289	0.711	0.000
L21 Seborrhoeic dermatitis	0.289	0.711	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.288	0.712	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.287	0.712	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.287	0.712	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.287	0.712	0.000
W19.4 Street and highway	0.288	0.712	0.000
Q89.2 Congenital malformations of other endocrine glands	0.287	0.713	0.000
E80.4 Gilbert's syndrome	0.284	0.716	0.000
L10-L14 Bullous disorders	0.283	0.717	0.000
G90.2 Horner's syndrome	0.283	0.717	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.283	0.717	0.000
Q25.1 Coarctation of aorta	0.283	0.717	0.000
F60 Specific personality disorders	0.283	0.717	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.282	0.717	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.282	0.718	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.282	0.718	0.000
W14 Fall from tree	0.282	0.718	0.000
W12 Fall on and from scaffolding	0.282	0.718	0.000
W09 Fall involving playground equipment	0.282	0.718	0.000
W05 Fall involving wheelchair	0.282	0.718	0.000
W04 Fall while being carried or supported by other persons	0.282	0.718	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.282	0.718	0.000
W00 Fall on same level involving ice and snow	0.282	0.718	0.000
W15 Fall from cliff	0.280	0.720	0.000
Q26 Congenital malformations of great veins	0.279	0.720	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.279	0.720	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.279	0.720	0.000
Q25.6 Stenosis of pulmonary artery	0.279	0.721	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations