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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs359312
log Bayes Factor = 3.58094
Chromosome 10   position 17,388,143  (GRCh37) Explore rs359312 on Ensembl!
Variant rs359312 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.981 0.019 0.000
Chapter XXI Factors influencing health status and contact with health services
0.980 0.020 0.000
R10 Abdominal and pelvic pain
0.972 0.028 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.966 0.034 0.000
Chapter II Neoplasms
0.965 0.035 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.954 0.046 0.000
Chapter XIV Diseases of the genitourinary system
0.948 0.052 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.927 0.073 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.925 0.075 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.919 0.081 0.000
D10-D36 Benign neoplasms
0.918 0.082 0.000
R10.4 Other and unspecified abdominal pain
0.916 0.084 0.000
Chapter XI Diseases of the digestive system
0.908 0.092 0.000
R19.4 Change in bowel habit
0.887 0.113 0.000
Z92 Personal history of medical treatment
0.887 0.113 0.000
R10.1 Pain localised to upper abdomen
0.886 0.114 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.874 0.126 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.868 0.132 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.868 0.132 0.000
H30-H36 Disorders of choroid and retina
0.867 0.133 0.000
K55-K64 Other diseases of intestines
0.863 0.137 0.000
R11 Nausea and vomiting
0.858 0.142 0.000
R19.5 Other fecal abnormalities
0.857 0.142 0.000
H25-H28 Disorders of lens
0.841 0.159 0.000
N40-N51 Diseases of male genital organs
0.839 0.161 0.000
Z02 Examination and encounter for administrative purposes
0.832 0.168 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.817 0.183 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.811 0.189 0.000
M15-M19 Arthrosis
0.802 0.198 0.000
Z96 Presence of other functional implants
0.798 0.202 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.794 0.206 0.000
R13 Dysphagia
0.793 0.207 0.000
Z95.0 Presence of cardiac pacemaker
0.789 0.211 0.000
H53-H54 Visual disturbances and blindness
0.788 0.212 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.788 0.212 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.786 0.214 0.000
R15 Faecal incontinence
0.786 0.214 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.785 0.215 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.784 0.216 0.000
R30-R39 Symptoms and signs involving the urinary system
0.782 0.218 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.782 0.218 0.000
K57 Diverticular disease of intestine
0.779 0.221 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.778 0.222 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.776 0.224 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.776 0.224 0.000
D12.0 Caecum
0.769 0.231 0.000
H35 Other retinal disorders
0.766 0.234 0.000
Z02.8 Other examinations for administrative purposes
0.765 0.235 0.000
K62 Other diseases of anus and rectum
0.762 0.238 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.762 0.238 0.000
H40-H42 Glaucoma
0.759 0.241 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.757 0.243 0.000
Chapter VI Diseases of the nervous system
0.753 0.247 0.000
N30-N39 Other diseases of urinary system
0.748 0.252 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.742 0.258 0.000
N93 Other abnormal uterine and vaginal bleeding
0.739 0.261 0.000
D00-D09 In situ neoplasms
0.734 0.265 0.000
M05-M14 Inflammatory polyarthropathies
0.734 0.266 0.000
K62.5 Haemorrhage of anus and rectum
0.733 0.267 0.000
Z12 Special screening examination for neoplasms
0.732 0.267 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.732 0.268 0.000
D12.5 Sigmoid colon
0.732 0.268 0.000
Chapter IX Diseases of the circulatory system
0.731 0.269 0.000
M50-M54 Other dorsopathies
0.728 0.272 0.000
Z95.1 Presence of aortocoronary bypass graft
0.728 0.272 0.000
D17 Benign lipomatous neoplasm
0.728 0.272 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.724 0.276 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.724 0.276 0.000
H25 Senile cataract
0.723 0.277 0.000
M20-M25 Other joint disorders
0.723 0.277 0.000
R14 Flatulence and related conditions
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Chapter VIII Diseases of the ear and mastoid process
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
R47-R49 Symptoms and signs involving speech and voice
0.716 0.284 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.716 0.284 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.715 0.285 0.000
R18 Ascites
0.715 0.285 0.000
R17 Unspecified jaundice
0.715 0.285 0.000
R12 Heartburn
0.710 0.290 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
H43-H45 Disorders of vitreous body and globe
0.703 0.297 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.703 0.297 0.000
H10-H13 Disorders of conjunctiva
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.703 0.297 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.702 0.298 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.701 0.299 0.000
Z92.3 Personal history of irradiation
0.698 0.302 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.697 0.303 0.000
R10.2 Pelvic and perineal pain
0.697 0.303 0.000
R10.0 Acute abdomen
0.697 0.303 0.000
Z85 Personal history of malignant neoplasm
0.696 0.303 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.696 0.304 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.696 0.304 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.694 0.306 0.000
H35.3 Degeneration of macula and posterior pole
0.694 0.306 0.000
Z80 Family history of malignant neoplasm
0.693 0.307 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.693 0.307 0.000
R19.6 Halitosis
0.693 0.307 0.000
R19.3 Abdominal rigidity
0.693 0.307 0.000
R19.2 Visible peristalsis
0.693 0.307 0.000
R19.1 Abnormal bowel sounds
0.693 0.307 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.692 0.308 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.692 0.308 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.692 0.308 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.692 0.308 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.692 0.308 0.000
C51-C58 Malignant neoplasms of female genital organs
0.692 0.308 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.692 0.308 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.692 0.308 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.692 0.308 0.000
C15-C26 Malignant neoplasms of digestive organs
0.692 0.308 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.692 0.308 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.689 0.311 0.000
H02 Other disorders of eyelid
0.687 0.312 0.000
K63 Other diseases of intestine
0.687 0.313 0.000
C64-C68 Malignant neoplasms of urinary tract
0.686 0.314 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.685 0.315 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.684 0.316 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.684 0.316 0.000
Z98 Other postsurgical states
0.684 0.316 0.000
Z97 Presence of other devices
0.684 0.316 0.000
Z94 Transplanted organ and tissue status
0.684 0.316 0.000
Z93 Artificial opening status
0.684 0.316 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.684 0.316 0.000
Z89 Acquired absence of limb
0.684 0.316 0.000
Z84 Family history of other conditions
0.684 0.316 0.000
Z83 Family history of other specific disorders
0.684 0.316 0.000
Z81 Family history of mental and behavioural disorders
0.684 0.316 0.000
N97 Female infertility
0.681 0.319 0.000
R10.3 Pain localised to other parts of lower abdomen
0.681 0.319 0.000
N99-N99 Other disorders of the genitourinary system
0.680 0.320 0.000
N60-N64 Disorders of breast
0.680 0.320 0.000
N25-N29 Other disorders of kidney and ureter
0.680 0.320 0.000
N10-N16 Renal tubulo-interstitial diseases
0.680 0.320 0.000
N00-N08 Glomerular diseases
0.680 0.320 0.000
D25 Leiomyoma of uterus
0.679 0.321 0.000
Chapter I Certain infectious and parasitic diseases
0.675 0.324 0.000
M19 Other arthrosis
0.671 0.329 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.671 0.329 0.000
C60-C63 Malignant neoplasms of male genital organs
0.671 0.329 0.000
Chapter V Mental and behavioural disorders
0.670 0.330 0.000
N40 Hyperplasia of prostate
0.669 0.331 0.000
H36 Retinal disorders in diseases classified elsewhere
0.668 0.332 0.000
K20 Oesophagitis
0.668 0.332 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.667 0.333 0.000
Chapter XX External causes of morbidity and mortality
0.666 0.333 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.665 0.335 0.000
Z95.4 Presence of other heart-valve replacement
0.665 0.335 0.000
Z95.3 Presence of xenogenic heart valve
0.665 0.335 0.000
Z95.2 Presence of prosthetic heart valve
0.665 0.335 0.000
D12.3 Transverse colon
0.664 0.335 0.000
Z96.6 Presence of orthopaedic joint implants
0.664 0.336 0.000
Z13 Special screening examination for other diseases and disorders
0.663 0.337 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.663 0.337 0.000
Z10 Routine general health check-up of defined subpopulation
0.663 0.337 0.000
Z04 Examination and observation for other reasons
0.663 0.337 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.663 0.337 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.663 0.337 0.000
D12.8 Rectum
0.659 0.340 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.659 0.341 0.000
M91-M94 Chondropathies
0.659 0.341 0.000
M86-M90 Other osteopathies
0.659 0.341 0.000
M65-M68 Disorders of synovium and tendon
0.659 0.341 0.000
M60-M63 Disorders of muscles
0.659 0.341 0.000
M45-M49 Spondylopathies
0.659 0.341 0.000
M40-M43 Deforming dorsopathies
0.659 0.341 0.000
M00-M03 Infectious arthropathies
0.659 0.341 0.000
D36 Benign neoplasm of other and unspecified sites
0.658 0.342 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.658 0.342 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.658 0.342 0.000
D32 Benign neoplasm of meninges
0.658 0.342 0.000
D31 Benign neoplasm of eye and adnexa
0.658 0.342 0.000
D30 Benign neoplasm of urinary organs
0.658 0.342 0.000
D29 Benign neoplasm of male genital organs
0.658 0.342 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.658 0.342 0.000
D26 Other benign neoplasms of uterus
0.658 0.342 0.000
D23 Other benign neoplasms of skin
0.658 0.342 0.000
D22 Melanocytic naevi
0.658 0.342 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.658 0.342 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.658 0.342 0.000
D19 Benign neoplasm of mesothelial tissue
0.658 0.342 0.000
D18 Haemangioma and lymphangioma, any site
0.658 0.342 0.000
D16 Benign neoplasm of bone and articular cartilage
0.658 0.342 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.658 0.342 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.658 0.342 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.658 0.342 0.000
D11 Benign neoplasm of major salivary glands
0.658 0.342 0.000
D10 Benign neoplasm of mouth and pharynx
0.658 0.342 0.000
D34 Benign neoplasm of thyroid gland
0.658 0.342 0.000
D27 Benign neoplasm of ovary
0.658 0.342 0.000
D24 Benign neoplasm of breast
0.658 0.342 0.000
K70-K77 Diseases of liver
0.658 0.342 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.658 0.342 0.000
N48 Other disorders of penis
0.657 0.343 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.656 0.344 0.000
M17 Gonarthrosis [arthrosis of knee]
0.656 0.344 0.000
K35-K38 Diseases of appendix
0.651 0.349 0.000
H53 Visual disturbances
0.650 0.350 0.000
D12.4 Descending colon
0.647 0.353 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.646 0.354 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.645 0.355 0.000
I20-I25 Ischaemic heart diseases
0.644 0.356 0.000
K30 Dyspepsia
0.643 0.357 0.000
C44 Other malignant neoplasms of skin
0.640 0.360 0.000
H26 Other cataract
0.640 0.360 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.639 0.361 0.000
H52 Disorders of refraction and accommodation
0.639 0.361 0.000
Z86 Personal history of certain other diseases
0.639 0.361 0.000
H25.1 Senile nuclear cataract
0.639 0.361 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.636 0.363 0.000
Z92.9 Personal history of medical treatment, unspecified
0.636 0.364 0.000
Z92.8 Personal history of other medical treatment
0.636 0.364 0.000
Z92.5 Personal history of rehabilitation measures
0.636 0.364 0.000
Z92.0 Personal history of contraception
0.636 0.364 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.635 0.365 0.000
N20-N23 Urolithiasis
0.633 0.367 0.000
E10-E14 Diabetes mellitus
0.633 0.367 0.000
C50-C50 Malignant neoplasm of breast
0.633 0.367 0.000
R79 Other abnormal findings of blood chemistry
0.632 0.368 0.000
N85.2 Hypertrophy of uterus
0.631 0.369 0.000
M80-M85 Disorders of bone density and structure
0.630 0.369 0.000
K65-K67 Diseases of peritoneum
0.627 0.373 0.000
R04 Haemorrhage from respiratory passages
0.627 0.373 0.000
D12.2 Ascending colon
0.625 0.374 0.000
M70-M79 Other soft tissue disorders
0.623 0.377 0.000
N98 Complications associated with artificial fertilisation
0.622 0.377 0.000
N91 Absent, scanty and rare menstruation
0.622 0.377 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.622 0.377 0.000
N89 Other noninflammatory disorders of vagina
0.622 0.377 0.000
N88 Other noninflammatory disorders of cervix uteri
0.622 0.377 0.000
N87 Dysplasia of cervix uteri
0.622 0.377 0.000
N82 Fistulae involving female genital tract
0.622 0.377 0.000
N80 Endometriosis
0.622 0.377 0.000
N96 Habitual aborter
0.622 0.377 0.000
N86 Erosion and ectropion of cervix uteri
0.622 0.377 0.000
D12.9 Anus and anal canal
0.622 0.377 0.000
D12.7 Rectosigmoid junction
0.622 0.377 0.000
D12.1 Appendix
0.622 0.377 0.000
H34 Retinal vascular occlusions
0.621 0.378 0.000
H33 Retinal detachments and breaks
0.621 0.378 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.621 0.378 0.000
H31 Other disorders of choroid
0.621 0.378 0.000
H30 Chorioretinal inflammation
0.621 0.378 0.000
R35 Polyuria
0.621 0.379 0.000
R33 Retention of urine
0.620 0.380 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.620 0.380 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.619 0.381 0.000
K61 Abscess of anal and rectal regions
0.619 0.381 0.000
K60 Fissure and fistula of anal and rectal regions
0.619 0.381 0.000
K55 Vascular disorders of intestine
0.619 0.381 0.000
K22 Other diseases of oesophagus
0.617 0.382 0.000
D12.6 Colon, unspecified
0.614 0.386 0.000
N93.0 Postcoital and contact bleeding
0.610 0.390 0.000
Z96.1 Presence of intraocular lens
0.608 0.392 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.608 0.392 0.000
K58 Irritable bowel syndrome
0.608 0.392 0.000
H00 Hordeolum and chalazion
0.606 0.394 0.000
S70-S79 Injuries to the hip and thigh
0.605 0.395 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.603 0.397 0.000
H27 Other disorders of lens
0.603 0.397 0.000
M51 Other intervertebral disk disorders
0.602 0.397 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.602 0.398 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.602 0.398 0.000
N50 Other disorders of male genital organs
0.602 0.398 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.602 0.398 0.000
N45 Orchitis and epididymitis
0.602 0.398 0.000
N43 Hydrocele and spermatocele
0.602 0.398 0.000
N42 Other disorders of prostate
0.602 0.398 0.000
N41 Inflammatory diseases of prostate
0.602 0.398 0.000
N46 Male infertility
0.602 0.398 0.000
N44 Torsion of testis
0.602 0.398 0.000
N84 Polyp of female genital tract
0.601 0.399 0.000
R30 Pain associated with micturition
0.601 0.399 0.000
H40 Glaucoma
0.600 0.399 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.600 0.400 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.599 0.401 0.000
E00-E07 Disorders of thyroid gland
0.598 0.402 0.000
M23 Internal derangement of knee
0.598 0.402 0.000
K90-K93 Other diseases of the digestive system
0.596 0.403 0.000
Z02.9 Examination for administrative purposes, unspecified
0.596 0.404 0.000
Z02.7 Issue of medical certificate
0.596 0.404 0.000
Z02.6 Examination for insurance purposes
0.596 0.404 0.000
Z02.5 Examination for participation in sport
0.596 0.404 0.000
Z02.4 Examination for driving licence
0.596 0.404 0.000
Z02.3 Examination for recruitment to armed forces
0.596 0.404 0.000
Z02.2 Examination for admission to residential institution
0.596 0.404 0.000
Z02.1 Pre-employment examination
0.596 0.404 0.000
Z02.0 Examination for admission to educational institution
0.596 0.404 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.595 0.405 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.591 0.409 0.000
N39 Other disorders of urinary system
0.590 0.410 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.590 0.410 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.589 0.411 0.000
N17-N19 Renal failure
0.589 0.411 0.000
S00-S09 Injuries to the head
0.587 0.412 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.586 0.414 0.000
H05 Disorders of orbit
0.586 0.414 0.000
H04 Disorders of lachrymal system
0.586 0.414 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.586 0.414 0.000
H01 Other inflammation of eyelid
0.586 0.414 0.000
N95 Menopausal and other perimenopausal disorders
0.585 0.414 0.000
M17.1 Other primary gonarthrosis
0.585 0.415 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.582 0.418 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.582 0.418 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.581 0.418 0.000
Z09.4 Follow-up examination after treatment of fracture
0.581 0.418 0.000
Z09.3 Follow-up examination after psychotherapy
0.581 0.418 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.581 0.418 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.581 0.418 0.000
N32 Other disorders of bladder
0.579 0.421 0.000
H02.8 Other specified disorders of eyelid
0.579 0.421 0.000
M19.9 Arthrosis, unspecified
0.578 0.422 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.578 0.422 0.000
K40-K46 Hernia
0.577 0.423 0.000
M16 Coxarthrosis [arthrosis of hip]
0.577 0.423 0.000
Z86.0 Personal history of other neoplasms
0.576 0.424 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.576 0.424 0.000
M18 Arthrosis of first carpometacarpal joint
0.575 0.425 0.000
M15 Polyarthrosis
0.575 0.425 0.000
S80-S89 Injuries to the knee and lower leg
0.575 0.425 0.000
M06 Other rheumatoid arthritis
0.573 0.426 0.000
E70-E90 Metabolic disorders
0.573 0.427 0.000
Z96.9 Presence of functional implant, unspecified
0.572 0.428 0.000
Z96.8 Presence of other specified functional implants
0.572 0.428 0.000
Z96.7 Presence of other bone and tendon implants
0.572 0.428 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.572 0.428 0.000
Z96.4 Presence of endocrine implants
0.572 0.428 0.000
Z96.3 Presence of artificial larynx
0.572 0.428 0.000
Z96.2 Presence of otological and audiological implants
0.572 0.428 0.000
Z96.0 Presence of urogenital implants
0.572 0.428 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.571 0.429 0.000
K50-K52 Noninfective enteritis and colitis
0.570 0.430 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.569 0.431 0.000
T79-T79 Certain early complications of trauma
0.569 0.431 0.000
T66-T78 Other and unspecified effects of external causes
0.569 0.431 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.569 0.431 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.569 0.431 0.000
T33-T35 Frostbite
0.569 0.431 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.569 0.431 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.569 0.431 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.569 0.431 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.569 0.431 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.569 0.431 0.000
T00-T07 Injuries involving multiple body regions
0.569 0.431 0.000
S90-S99 Injuries to the ankle and foot
0.569 0.431 0.000
S60-S69 Injuries to the wrist and hand
0.569 0.431 0.000
S40-S49 Injuries to the shoulder and upper arm
0.569 0.431 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.569 0.431 0.000
S20-S29 Injuries to the thorax
0.569 0.431 0.000
S10-S19 Injuries to the neck
0.569 0.431 0.000
D05 Carcinoma in situ of breast
0.569 0.431 0.000
K08 Other disorders of teeth and supporting structures
0.569 0.431 0.000
S50-S59 Injuries to the elbow and forearm
0.565 0.435 0.000
H54 Blindness and low vision
0.565 0.435 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.565 0.435 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.565 0.435 0.000
N85.7 Haematometra
0.565 0.435 0.000
N85.6 Intra-uterine synechiae
0.565 0.435 0.000
N85.5 Inversion of uterus
0.565 0.435 0.000
N85.4 Malposition of uterus
0.565 0.435 0.000
N85.3 Subinvolution of uterus
0.565 0.435 0.000
N85.1 Endometrial adenomatous hyperplasia
0.565 0.435 0.000
N85.0 Endometrial glandular hyperplasia
0.565 0.435 0.000
K31 Other diseases of stomach and duodenum
0.565 0.435 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.564 0.436 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.563 0.437 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.563 0.437 0.000
R77 Other abnormalities of plasma proteins
0.563 0.437 0.000
R76 Other abnormal immunological findings in serum
0.563 0.437 0.000
R74 Abnormal serum enzyme levels
0.563 0.437 0.000
R73 Elevated blood glucose level
0.563 0.437 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.563 0.437 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.563 0.437 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.563 0.437 0.000
R71 Abnormality of red blood cells
0.563 0.437 0.000
C80 Malignant neoplasm without specification of site
0.562 0.437 0.000
C79 Secondary malignant neoplasm of other sites
0.562 0.437 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.562 0.437 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.562 0.438 0.000
K63.5 Polyp of colon
0.562 0.438 0.000
R36 Urethral discharge
0.561 0.439 0.000
R34 Anuria and oliguria
0.561 0.439 0.000
R32 Unspecified urinary incontinence
0.561 0.439 0.000
H51 Other disorders of binocular movement
0.560 0.439 0.000
H50 Other strabismus
0.560 0.439 0.000
H49 Paralytic strabismus
0.560 0.439 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.558 0.441 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.558 0.441 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.558 0.441 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.558 0.441 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.558 0.441 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.558 0.441 0.000
E50-E64 Other nutritional deficiencies
0.557 0.442 0.000
E40-E46 Malnutrition
0.557 0.442 0.000
E20-E35 Disorders of other endocrine glands
0.557 0.442 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.557 0.442 0.000
C43 Malignant melanoma of skin
0.556 0.443 0.000
D25.2 Subserosal leiomyoma of uterus
0.556 0.444 0.000
M13 Other arthritis
0.553 0.447 0.000
R06 Abnormalities of breathing
0.551 0.448 0.000
H53.0 Amblyopia ex anopsia
0.550 0.449 0.000
K26 Duodenal ulcer
0.549 0.450 0.000
R05 Cough
0.549 0.451 0.000
H35.9 Retinal disorder, unspecified
0.549 0.451 0.000
H35.8 Other specified retinal disorders
0.549 0.451 0.000
H35.7 Separation of retinal layers
0.549 0.451 0.000
H35.6 Retinal haemorrhage
0.549 0.451 0.000
H35.5 Hereditary retinal dystrophy
0.549 0.451 0.000
H35.4 Peripheral retinal degeneration
0.549 0.451 0.000
H35.2 Other proliferative retinopathy
0.549 0.451 0.000
H35.1 Retinopathy of prematurity
0.549 0.451 0.000
H35.0 Background retinopathy and retinal vascular changes
0.549 0.451 0.000
K62.9 Disease of anus and rectum, unspecified
0.546 0.453 0.000
K62.7 Radiation proctitis
0.546 0.453 0.000
K62.6 Ulcer of anus and rectum
0.546 0.453 0.000
K62.4 Stenosis of anus and rectum
0.546 0.453 0.000
K62.3 Rectal prolapse
0.546 0.453 0.000
K62.2 Anal prolapse
0.546 0.453 0.000
K62.0 Anal polyp
0.546 0.453 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.546 0.454 0.000
R01 Cardiac murmurs and other cardiac sounds
0.546 0.454 0.000
R02 Gangrene, not elsewhere classified
0.546 0.454 0.000
N97.9 Female infertility, unspecified
0.546 0.454 0.000
R00 Abnormalities of heart beat
0.546 0.454 0.000
N92 Excessive, frequent and irregular menstruation
0.546 0.454 0.000
R42 Dizziness and giddiness
0.546 0.454 0.000
Z90.1 Acquired absence of breast(s)
0.545 0.455 0.000
H42 Glaucoma in diseases classified elsewhere
0.544 0.455 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.544 0.455 0.000
R20 Disturbances of skin sensation
0.544 0.456 0.000
K28 Gastrojejunal ulcer
0.543 0.457 0.000
K27 Peptic ulcer, site unspecified
0.543 0.457 0.000
K25 Gastric ulcer
0.543 0.457 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.543 0.457 0.000
I20 Angina pectoris
0.541 0.459 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.541 0.459 0.000
G90-G99 Other disorders of the nervous system
0.540 0.460 0.000
G70-G73 Diseases of myoneural junction and muscle
0.540 0.460 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.540 0.460 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.540 0.460 0.000
G30-G32 Other degenerative diseases of the nervous system
0.540 0.460 0.000
G20-G26 Extrapyramidal and movement disorders
0.540 0.460 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.540 0.460 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.540 0.460 0.000
M10 Gout
0.538 0.462 0.000
Chapter X Diseases of the respiratory system
0.537 0.462 0.000
H52.1 Myopia
0.537 0.463 0.000
N37 Urethral disorders in diseases classified elsewhere
0.537 0.463 0.000
N36 Other disorders of urethra
0.537 0.463 0.000
N34 Urethritis and urethral syndrome
0.537 0.463 0.000
N33 Bladder disorders in diseases classified elsewhere
0.537 0.463 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.537 0.463 0.000
N30 Cystitis
0.537 0.463 0.000
C77.3 Axillary and upper limb lymph nodes
0.534 0.466 0.000
N72 Inflammatory disease of cervix uteri
0.533 0.467 0.000
C44.5 Skin of trunk
0.532 0.468 0.000
K59 Other functional intestinal disorders
0.531 0.469 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.530 0.470 0.000
R04.2 Haemoptysis
0.530 0.470 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.527 0.473 0.000
M25 Other joint disorders, not elsewhere classified
0.527 0.473 0.000
N48.6 Balanitis xerotica obliterans
0.527 0.473 0.000
D09 Carcinoma in situ of other and unspecified sites
0.527 0.473 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.527 0.473 0.000
D06 Carcinoma in situ of cervix uteri
0.527 0.473 0.000
D04 Carcinoma in situ of skin
0.527 0.473 0.000
D03 Melanoma in situ
0.527 0.473 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.527 0.473 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.527 0.473 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.527 0.473 0.000
M14 Arthropathies in other diseases classified elsewhere
0.526 0.473 0.000
M12 Other specific arthropathies
0.526 0.473 0.000
M11 Other crystal arthropathies
0.526 0.473 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.526 0.473 0.000
M08 Juvenile arthritis
0.526 0.473 0.000
M07 Psoriatic and enteropathic arthropathies
0.526 0.473 0.000
M05 Seropositive rheumatoid arthritis
0.526 0.473 0.000
H36.0 Diabetic retinopathy
0.526 0.474 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.525 0.475 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.525 0.475 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.525 0.475 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.525 0.475 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.525 0.475 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.525 0.475 0.000
Z12.3 Special screening examination for neoplasm of breast
0.525 0.475 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.525 0.475 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.525 0.475 0.000
R23 Other skin changes
0.525 0.475 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.525 0.475 0.000
I05-I09 Chronic rheumatic heart diseases
0.524 0.476 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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