TreeWAS – Variant ID: rs362296

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.9 Rheumatoid arthritis, unspecified	0.000	0.919	0.081
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.920	0.080
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.925	0.075
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.929	0.071
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.931	0.069
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.936	0.064
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.937	0.063
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.937	0.063
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.938	0.062
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.940	0.060
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.944	0.056
S42.00 Fracture of clavicle (closed)	0.052	0.948	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.954	0.046
S06.30 Focal brain injury (without open intracranial wound)	0.032	0.968	0.000
S06.3 Focal brain injury	0.031	0.969	0.000
S06 Intracranial injury	0.030	0.970	0.000
S06.8 Other intracranial injuries	0.028	0.972	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.027	0.973	0.000
K80 Cholelithiasis	0.000	0.973	0.027
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.974	0.026
S06.80 Other intracranial injuries (without open intracranial wound)	0.026	0.974	0.000
S06.1 Traumatic cerebral oedema	0.025	0.974	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.025	0.975	0.000
S06.0 Concussion	0.025	0.975	0.000
S42.0 Fracture of clavicle	0.025	0.975	0.000
S06.9 Intracranial injury, unspecified	0.024	0.976	0.000
S06.4 Epidural haemorrhage	0.024	0.976	0.000
S06.2 Diffuse brain injury	0.024	0.976	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.977	0.023
S06.31 Focal brain injury (with open intracranial wound)	0.022	0.978	0.000
S06.7 Intracranial injury with prolonged coma	0.022	0.978	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.022	0.978	0.000
S06.00 Concussion (without open intracranial wound)	0.021	0.979	0.000
S06.5 Traumatic subdural haemorrhage	0.020	0.980	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.020	0.980	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.020	0.980	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.020	0.980	0.000
K80.3 Calculus of bile duct with cholangitis	0.000	0.980	0.019
S06.40 Epidural haemorrhage (without open intracranial wound)	0.019	0.981	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.019	0.981	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.018	0.981	0.000
S06.01 Concussion (with open intracranial wound)	0.018	0.982	0.000
S42.01 Fracture of clavicle (open)	0.018	0.982	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.017	0.982	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.982	0.018
S06.41 Epidural haemorrhage (with open intracranial wound)	0.017	0.983	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.017	0.983	0.000
M06 Other rheumatoid arthritis	0.000	0.983	0.017
E53.8 Deficiency of other specified B group vitamins	0.000	0.984	0.016
K80.4 Calculus of bile duct with cholecystitis	0.000	0.984	0.016
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.016	0.984	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.016	0.984	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.985	0.015
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.015	0.985	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.986	0.014
M06.3 Rheumatoid nodule	0.000	0.987	0.013
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.013	0.987	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.987	0.013
M06.2 Rheumatoid bursitis	0.000	0.988	0.012
M06.1 Adult-onset Still's disease	0.000	0.988	0.012
R29.6 Tendency to fall, not elsewhere classified	0.000	0.988	0.012
E53 Deficiency of other B group vitamins	0.000	0.988	0.012
M06.4 Inflammatory polyarthropathy	0.000	0.989	0.011
M06.8 Other specified rheumatoid arthritis	0.000	0.989	0.011
R29.2 Abnormal reflex	0.000	0.989	0.011
E53.9 Vitamin B deficiency, unspecified	0.000	0.990	0.010
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.990	0.010
M06.34 Rheumatoid nodule (Hand)	0.000	0.990	0.010
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.990	0.010
R29.1 Meningismus	0.000	0.990	0.010
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.990	0.009
M06.38 Rheumatoid nodule (Other)	0.000	0.990	0.009
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.990	0.009
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.990	0.009
M06.33 Rheumatoid nodule (Forearm)	0.000	0.990	0.009
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.990	0.009
R29.4 Clicking hip	0.000	0.991	0.009
R29.3 Abnormal posture	0.000	0.991	0.009
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.991	0.009
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.991	0.009
R29.0 Tetany	0.000	0.991	0.009
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.991	0.009
M06.18 Adult-onset Still's disease (Other)	0.000	0.991	0.009
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.991	0.009
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.991	0.009
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.991	0.009
M06.14 Adult-onset Still's disease (Hand)	0.000	0.991	0.009
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.991	0.009
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.991	0.009
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.991	0.009
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.991	0.009
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.991	0.009
M06.28 Rheumatoid bursitis (Other)	0.000	0.991	0.009
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.991	0.009
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.991	0.009
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.991	0.009
M06.24 Rheumatoid bursitis (Hand)	0.000	0.991	0.009
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.991	0.009
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.991	0.009
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.991	0.009
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.991	0.009
K80.8 Other cholelithiasis	0.000	0.991	0.009
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.991	0.009
E53.1 Pyridoxine deficiency	0.000	0.991	0.008
E53.0 Riboflavin deficiency	0.000	0.991	0.008
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.992	0.008
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.992	0.008
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.992	0.008
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.992	0.008
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.992	0.008
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.992	0.008
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.992	0.008
Y57.9 Drug or medicament, unspecified	0.008	0.992	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.992	0.008
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.992	0.008
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.992	0.008
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.992	0.008
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.992	0.008
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.992	0.008
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.992	0.008
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.992	0.008
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.992	0.008
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.992	0.008
R47.0 Dysphasia and aphasia	0.000	0.993	0.007
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.993	0.007
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.993	0.006
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.007	0.993	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.994	0.006
T84.0 Mechanical complication of internal joint prosthesis	0.006	0.994	0.000
D86 Sarcoidosis	0.000	0.994	0.006
R47.1 Dysarthria and anarthria	0.000	0.994	0.006
D86.0 Sarcoidosis of lung	0.000	0.994	0.006
R47 Speech disturbances, not elsewhere classified	0.000	0.994	0.006
D86.1 Sarcoidosis of lymph nodes	0.000	0.994	0.006
M06.0 Seronegative rheumatoid arthritis	0.000	0.994	0.005
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.995	0.005
Z36.0 Antenatal screening for chromosomal anomalies	0.005	0.995	0.000
Y83.4 Other reconstructive surgery	0.005	0.995	0.000
Z47.8 Other specified orthopaedic follow-up care	0.005	0.995	0.000
N81.3 Complete uterovaginal prolapse	0.005	0.995	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.995	0.005
S42 Fracture of shoulder and upper arm	0.005	0.995	0.000
D86.3 Sarcoidosis of skin	0.000	0.995	0.005
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.005	0.995	0.000
S00-S09 Injuries to the head	0.005	0.995	0.000
R87.6 Abnormal cytological findings	0.000	0.995	0.005
S02.10 Fracture of base of skull (closed)	0.005	0.995	0.000
M16.0 Primary coxarthrosis, bilateral	0.004	0.996	0.000
M16.3 Other dysplastic coxarthrosis	0.004	0.996	0.000
S02.1 Fracture of base of skull	0.004	0.996	0.000
L60.8 Other nail disorders	0.004	0.996	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.996	0.004
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.996	0.004
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.996	0.004
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.996	0.004
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.996	0.004
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.996	0.004
S02 Fracture of skull and facial bones	0.004	0.996	0.000
E50-E64 Other nutritional deficiencies	0.000	0.996	0.004
M16 Coxarthrosis [arthrosis of hip]	0.004	0.996	0.000
M16.5 Other posttraumatic coxarthrosis	0.004	0.996	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.996	0.004
R47.8 Other and unspecified speech disturbances	0.000	0.996	0.004
S46.2 Injury of muscle and tendon of other parts of biceps	0.004	0.996	0.000
S04 Injury of cranial nerves	0.004	0.996	0.000
T78.4 Allergy, unspecified	0.004	0.996	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.996	0.004
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.004	0.996	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.996	0.004
S42.7 Multiple fractures of clavicle, scapula and humerus	0.004	0.996	0.000
S02.2 Fracture of nasal bones	0.004	0.996	0.000
N43.3 Hydrocele, unspecified	0.004	0.996	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.004	0.996	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.004	0.996	0.000
I86.1 Scrotal varices	0.004	0.996	0.000
S08 Traumatic amputation of part of head	0.003	0.996	0.000
S07 Crushing injury of head	0.003	0.996	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.004	0.996	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.003	0.996	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
S04.5 Injury of facial nerve	0.003	0.997	0.000
S42.4 Fracture of lower end of humerus	0.003	0.997	0.000
W50.9 Unspecified place	0.003	0.997	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
J06.9 Acute upper respiratory infection, unspecified	0.003	0.997	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.997	0.003
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
S02.11 Fracture of base of skull (open)	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
S02.6 Fracture of mandible	0.003	0.997	0.000
M16.7 Other secondary coxarthrosis	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
E58 Dietary calcium deficiency	0.000	0.997	0.003
K75.0 Abscess of liver	0.000	0.997	0.003
S05 Injury of eye and orbit	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.003	0.997	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.997	0.003
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.003
E63 Other nutritional deficiencies	0.000	0.997	0.003
E50 Vitamin A deficiency	0.000	0.997	0.003
E60 Dietary zinc deficiency	0.000	0.997	0.003
E59 Dietary selenium deficiency	0.000	0.997	0.003
E52 Niacin deficiency [pellagra]	0.000	0.997	0.003
M16.4 Posttraumatic coxarthrosis, bilateral	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
E61.2 Magnesium deficiency	0.000	0.997	0.003
K75.9 Inflammatory liver disease, unspecified	0.000	0.997	0.003
S01.2 Open wound of nose	0.003	0.997	0.000
E51 Thiamine deficiency	0.000	0.997	0.003
E54 Ascorbic acid deficiency	0.000	0.997	0.003
S04.9 Injury of unspecified cranial nerve	0.003	0.997	0.000
S04.8 Injury of other cranial nerves	0.003	0.997	0.000
S04.7 Injury of accessory nerve	0.003	0.997	0.000
S04.6 Injury of acoustic nerve	0.003	0.997	0.000
S04.4 Injury of abducent nerve	0.003	0.997	0.000
S04.3 Injury of trigeminal nerve	0.003	0.997	0.000
S04.2 Injury of trochlear nerve	0.003	0.997	0.000
S04.1 Injury of oculomotor nerve	0.003	0.997	0.000
S04.0 Injury of optic nerve and pathways	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.000	0.997	0.003
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.000	0.997	0.003
E56 Other vitamin deficiencies	0.000	0.997	0.003
I86.8 Varicose veins of other specified sites	0.003	0.997	0.000
S01.4 Open wound of cheek and temporomandibular area	0.003	0.997	0.000
S01 Open wound of head	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.000	0.997	0.003
S05.8 Other injuries of eye and orbit	0.003	0.997	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.003	0.997	0.000
S02.5 Fracture of tooth	0.003	0.997	0.000
S01.3 Open wound of ear	0.003	0.997	0.000
S46.3 Injury of muscle and tendon of triceps	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.003	0.997	0.000
K75.4 Autoimmune hepatitis	0.000	0.997	0.003
T92.0 Sequelae of open wound of upper limb	0.003	0.997	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.997	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.000	0.997	0.003
I86 Varicose veins of other sites	0.003	0.997	0.000
S07.9 Crushing injury of head, part unspecified	0.003	0.997	0.000
S07.8 Crushing injury of other parts of head	0.003	0.997	0.000
S07.1 Crushing injury of skull	0.003	0.997	0.000
S07.0 Crushing injury of face	0.003	0.997	0.000
S08.9 Traumatic amputation of unspecified part of head	0.003	0.997	0.000
S08.8 Traumatic amputation of other parts of head	0.003	0.997	0.000
S08.1 Traumatic amputation of ear	0.003	0.997	0.000
S08.0 Avulsion of scalp	0.003	0.997	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
M16.1 Other primary coxarthrosis	0.003	0.997	0.000
S01.7 Multiple open wounds of head	0.003	0.997	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.003	0.997	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.003	0.997	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.003	0.997	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
S42.41 Fracture of lower end of humerus (open)	0.003	0.997	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.003	0.997	0.000
S03.4 Sprain and strain of jaw	0.003	0.997	0.000
S03.3 Dislocation of other and unspecified parts of head	0.003	0.997	0.000
S03.1 Dislocation of septal cartilage of nose	0.003	0.997	0.000
S03.0 Dislocation of jaw	0.003	0.997	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.997	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.003	0.997	0.000
E80.4 Gilbert's syndrome	0.000	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.003	0.997	0.000
E24 Cushing's syndrome	0.000	0.997	0.003
S02.81 Fractures of other skull and facial bones (open)	0.002	0.997	0.000
S42.1 Fracture of scapula	0.003	0.997	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.003	0.997	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.003	0.997	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.002	0.997	0.000
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
S02.61 Fracture of mandible (open)	0.002	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.003	0.997	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.002	0.997	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.003	0.997	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.997	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.003	0.997	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.003
S05.7 Avulsion of eye	0.002	0.997	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.997	0.000
Y57.6 Other diagnostic agents	0.002	0.997	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.997	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.997	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.997	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.997	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.997	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.997	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.997	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.997	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.997	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.997	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.997	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.997	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.997	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.997	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.997	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.997	0.002
E64.3 Sequelae of rickets	0.000	0.997	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.997	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.997	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.997	0.002
I86.2 Pelvic varices	0.003	0.997	0.000
E26 Hyperaldosteronism	0.000	0.997	0.003
S02.60 Fracture of mandible (closed)	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003
S03.2 Dislocation of tooth	0.002	0.997	0.000
W50.0 Home	0.002	0.997	0.000
S05.9 Injury of eye and orbit, part unspecified	0.002	0.997	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.997	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.997	0.002
E51.1 Beriberi	0.000	0.997	0.002
E61.9 Deficiency of nutrient element, unspecified	0.000	0.997	0.002
E61.8 Deficiency of other specified nutrient elements	0.000	0.997	0.002
E61.7 Deficiency of multiple nutrient elements	0.000	0.997	0.002
E61.6 Vanadium deficiency	0.000	0.997	0.002
E61.5 Molybdenum deficiency	0.000	0.997	0.002
E61.4 Chromium deficiency	0.000	0.997	0.002
E61.3 Manganese deficiency	0.000	0.997	0.002
E61.0 Copper deficiency	0.000	0.997	0.002
E28 Ovarian dysfunction	0.000	0.997	0.003
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.997	0.002
E26.0 Primary hyperaldosteronism	0.000	0.997	0.002
J98.0 Diseases of bronchus, not elsewhere classified	0.003	0.997	0.000
W50.2 School, other institution and public administrative area	0.002	0.997	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
S05.1 Contusion of eyeball and orbital tissues	0.002	0.998	0.000
E20 Hypoparathyroidism	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.002
E56.8 Deficiency of other vitamins	0.000	0.998	0.002
E56.0 Deficiency of vitamin E	0.000	0.998	0.002
L20.9 Atopic dermatitis, unspecified	0.002	0.998	0.000
W50.4 Street and highway	0.002	0.998	0.000
L60 Nail disorders	0.002	0.998	0.000
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
I86.4 Gastric varices	0.002	0.998	0.000
E40-E46 Malnutrition	0.000	0.998	0.002
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
Y60.0 During surgical operation	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
L60.3 Nail dystrophy	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
W10.4 Street and highway	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.000	0.998	0.002
W50.3 Sports and athletics area	0.002	0.998	0.000
W50.8 Other specified place	0.002	0.998	0.000
W50.7 Farm	0.002	0.998	0.000
W50.6 Industrial and construction area	0.002	0.998	0.000
W50.5 Trade and service area	0.002	0.998	0.000
W50.1 Residential institution	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E32 Diseases of thymus	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E25 Adrenogenital disorders	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
K11.1 Hypertrophy of salivary gland	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
E29 Testicular dysfunction	0.000	0.998	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.000	0.998	0.002
E55 Vitamin D deficiency	0.000	0.998	0.002
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
Z36 Antenatal screening	0.002	0.998	0.000
I86.3 Vulval varices	0.002	0.998	0.000
L60.9 Nail disorder, unspecified	0.002	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.002	0.998	0.000
E27.2 Addisonian crisis	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
E65 Localised adiposity	0.000	0.998	0.002
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
L60.5 Yellow nail syndrome	0.002	0.998	0.000
L60.4 Beau's lines	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
L20.8 Other atopic dermatitis	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
L60.1 Onycholysis	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.998	0.002
E45 Retarded development following protein-energy malnutrition	0.000	0.998	0.002
E43 Unspecified severe protein-energy malnutrition	0.000	0.998	0.002
E42 Marasmic kwashiorkor	0.000	0.998	0.002
E41 Nutritional marasmus	0.000	0.998	0.002
E40 Kwashiorkor	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
V28.5 Passenger injured in traffic accident	0.002	0.998	0.000
S40 Superficial injury of shoulder and upper arm	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
S48 Traumatic amputation of shoulder and upper arm	0.002	0.998	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S44 Injury of nerves at shoulder and upper arm level	0.002	0.998	0.000
S47 Crushing injury of shoulder and upper arm	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
H05.2 Exophthalmic conditions	0.000	0.998	0.002
W50.30 Hit, struck, kicked, twisted, bitten or scratched by another person; Sports and athletics area;While engaged in sports activity	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
N76.2 Acute vulvitis	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
I82 Other venous embolism and thrombosis	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
I25.2 Old myocardial infarction	0.000	0.998	0.002
L60.2 Onychogryphosis	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.000	0.998	0.002
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
S42.21 Fracture of upper end of humerus (open)	0.002	0.998	0.000
E55.0 Rickets, active	0.000	0.998	0.002
K11.9 Disease of salivary gland, unspecified	0.002	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
L60.0 Ingrowing nail	0.002	0.998	0.000
Z36.5 Antenatal screening for isoimmunisation	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations