TreeWAS – Variant ID: rs362540

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.082	0.918
N40 Hyperplasia of prostate	0.909	0.091	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.096	0.904
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.101	0.899
E00-E07 Disorders of thyroid gland	0.000	0.110	0.890
N42 Other disorders of prostate	0.881	0.119	0.000
N42.8 Other specified disorders of prostate	0.875	0.125	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.136	0.864
N42.1 Congestion and haemorrhage of prostate	0.861	0.139	0.000
N40-N51 Diseases of male genital organs	0.854	0.146	0.000
N42.2 Atrophy of prostate	0.851	0.149	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.267	0.733
N43 Hydrocele and spermatocele	0.725	0.275	0.000
N44 Torsion of testis	0.700	0.300	0.000
N42.9 Disorder of prostate, unspecified	0.686	0.314	0.000
E03.5 Myxoedema coma	0.000	0.342	0.658
E03.4 Atrophy of thyroid (acquired)	0.000	0.342	0.658
E03.3 Postinfectious hypothyroidism	0.000	0.342	0.658
E05.5 Thyroid crisis or storm	0.000	0.355	0.644
E05.4 Thyrotoxicosis factitia	0.000	0.355	0.644
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.355	0.644
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.355	0.644
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.362	0.638
E00 Congenital iodine-deficiency syndrome	0.000	0.362	0.638
N42.3 Dysplasia of prostate	0.606	0.393	0.000
E06 Thyroiditis	0.000	0.400	0.600
N43.3 Hydrocele, unspecified	0.595	0.405	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.593	0.407	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.419	0.581
E03.8 Other specified hypothyroidism	0.000	0.436	0.564
N43.2 Other hydrocele	0.554	0.446	0.000
N43.1 Infected hydrocele	0.539	0.461	0.000
N43.4 Spermatocele	0.532	0.468	0.000
N41 Inflammatory diseases of prostate	0.525	0.475	0.000
N43.0 Encysted hydrocele	0.520	0.480	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.501	0.499	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.505	0.495
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.507	0.493
N46 Male infertility	0.481	0.518	0.000
E06.5 Other chronic thyroiditis	0.000	0.521	0.479
N50 Other disorders of male genital organs	0.459	0.541	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.543	0.457
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.543	0.457
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.543	0.457
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.543	0.457
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.543	0.457
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.543	0.457
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.543	0.457
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.543	0.457
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.545	0.454
E07 Other disorders of thyroid	0.000	0.568	0.432
E06.4 Drug-induced thyroiditis	0.000	0.569	0.430
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.569	0.430
E06.0 Acute thyroiditis	0.000	0.569	0.430
E05.8 Other thyrotoxicosis	0.001	0.571	0.429
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.425	0.575	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.425	0.575	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.425	0.575	0.000
E06.3 Autoimmune thyroiditis	0.000	0.581	0.419
N41.2 Abscess of prostate	0.417	0.583	0.000
N50.9 Disorder of male genital organs, unspecified	0.413	0.586	0.000
N51.2 Balanitis in diseases classified elsewhere	0.406	0.594	0.000
E06.1 Subacute thyroiditis	0.000	0.601	0.399
N41.3 Prostatocystitis	0.376	0.624	0.000
N41.8 Other inflammatory diseases of prostate	0.373	0.626	0.000
E06.9 Thyroiditis, unspecified	0.000	0.630	0.370
N41.0 Acute prostatitis	0.362	0.638	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.359	0.641	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.359	0.641	0.000
E83 Disorders of mineral metabolism	0.000	0.659	0.341
N49.8 Inflammatory disorders of other specified male genital organs	0.339	0.660	0.000
N41.1 Chronic prostatitis	0.331	0.669	0.000
N45 Orchitis and epididymitis	0.328	0.672	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.327	0.673	0.000
N50.1 Vascular disorders of male genital organs	0.325	0.675	0.000
N49.2 Inflammatory disorders of scrotum	0.319	0.681	0.000
E83.5 Disorders of calcium metabolism	0.000	0.687	0.313
E07.1 Dyshormogenetic goitre	0.000	0.690	0.309
E07.0 Hypersecretion of calcitonin	0.000	0.690	0.309
K90 Intestinal malabsorption	0.000	0.694	0.306
N41.9 Inflammatory disease of prostate, unspecified	0.302	0.698	0.000
N42.0 Calculus of prostate	0.288	0.711	0.001
E07.8 Other specified disorders of thyroid	0.000	0.750	0.249
E83.8 Other disorders of mineral metabolism	0.000	0.755	0.244
E83.2 Disorders of zinc metabolism	0.000	0.755	0.244
E83.0 Disorders of copper metabolism	0.000	0.755	0.244
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.767	0.233
G35 Multiple sclerosis	0.000	0.778	0.222
K90.3 Pancreatic steatorrhoea	0.000	0.780	0.220
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.780	0.220
K90.1 Tropical sprue	0.000	0.780	0.220
K90.8 Other intestinal malabsorption	0.000	0.788	0.212
E07.9 Disorder of thyroid, unspecified	0.000	0.789	0.211
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.794	0.206
N50.0 Atrophy of testis	0.189	0.811	0.000
M20.1 Hallux valgus (acquired)	0.185	0.815	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.173	0.827	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.833	0.167
E83.4 Disorders of magnesium metabolism	0.000	0.847	0.153
K90.9 Intestinal malabsorption, unspecified	0.000	0.860	0.140
K72.9 Hepatic failure, unspecified	0.000	0.892	0.108
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.101	0.899	0.000
N50.8 Other specified disorders of male genital organs	0.089	0.911	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.915	0.085
N47 Redundant prepuce, phimosis and paraphimosis	0.083	0.917	0.000
E04 Other non-toxic goitre	0.001	0.923	0.077
K72.0 Acute and subacute hepatic failure	0.000	0.928	0.072
K72.1 Chronic hepatic failure	0.000	0.938	0.062
C44.3 Skin of other and unspecified parts of face	0.000	0.939	0.061
E04.0 Non-toxic diffuse goitre	0.000	0.942	0.057
K70-K77 Diseases of liver	0.000	0.944	0.056
E04.8 Other specified non-toxic goitre	0.001	0.944	0.055
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.945	0.054
K75 Other inflammatory liver diseases	0.000	0.948	0.052
K74 Fibrosis and cirrhosis of liver	0.000	0.950	0.050
K75.4 Autoimmune hepatitis	0.000	0.952	0.048
K73 Chronic hepatitis, not elsewhere classified	0.000	0.956	0.044
K74.0 Hepatic fibrosis	0.000	0.956	0.044
K75.8 Other specified inflammatory liver diseases	0.000	0.957	0.043
K74.5 Biliary cirrhosis, unspecified	0.000	0.959	0.041
K71 Toxic liver disease	0.000	0.959	0.041
K77 Liver disorders in diseases classified elsewhere	0.000	0.960	0.040
G36 Other acute disseminated demyelination	0.000	0.961	0.039
K74.3 Primary biliary cirrhosis	0.000	0.961	0.039
K73.9 Chronic hepatitis, unspecified	0.000	0.962	0.038
K75.9 Inflammatory liver disease, unspecified	0.000	0.962	0.038
K75.2 Nonspecific reactive hepatitis	0.000	0.963	0.037
K75.1 Phlebitis of portal vein	0.000	0.963	0.037
M35.0 Sicca syndrome [Sjogren]	0.000	0.963	0.037
K74.4 Secondary biliary cirrhosis	0.000	0.964	0.036
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.964	0.036
K74.1 Hepatic sclerosis	0.000	0.964	0.036
S62.20 Fracture of first metacarpal bone (closed)	0.036	0.964	0.000
N48 Other disorders of penis	0.036	0.964	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.965	0.035
M45.X9 Ankylosing spondylitis (Site unspecified)	0.035	0.965	0.000
K75.0 Abscess of liver	0.000	0.966	0.034
M20.3 Other deformity of hallux (acquired)	0.034	0.966	0.000
M20 Acquired deformities of fingers and toes	0.033	0.967	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.967	0.033
K71.0 Toxic liver disease with cholestasis	0.000	0.967	0.032
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.968	0.032
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.968	0.032
K74.6 Other and unspecified cirrhosis of liver	0.000	0.969	0.031
K71.9 Toxic liver disease, unspecified	0.000	0.971	0.029
K71.8 Toxic liver disease with other disorders of liver	0.000	0.971	0.029
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.971	0.029
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.971	0.029
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.971	0.029
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.971	0.029
K71.2 Toxic liver disease with acute hepatitis	0.000	0.971	0.029
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.971	0.029
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.971	0.029
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.971	0.029
G36.0 Neuromyelitis optica [Devic]	0.000	0.971	0.028
G36.9 Acute disseminated demyelination, unspecified	0.000	0.971	0.028
G36.8 Other specified acute disseminated demyelination	0.000	0.971	0.028
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.971	0.028
N48.5 Ulcer of penis	0.027	0.973	0.000
K76.6 Portal hypertension	0.000	0.974	0.026
M20.6 Acquired deformity of toe(s), unspecified	0.026	0.974	0.000
N48.1 Balanoposthitis	0.026	0.974	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.974	0.025
K90-K93 Other diseases of the digestive system	0.000	0.974	0.025
N48.3 Priapism	0.025	0.975	0.000
K76 Other diseases of liver	0.000	0.975	0.025
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.975	0.025
M45 Ankylosing spondylitis	0.025	0.975	0.000
K11.5 Sialolithiasis	0.023	0.977	0.000
N48.6 Balanitis xerotica obliterans	0.023	0.977	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.022	0.978	0.000
J38.4 Oedema of larynx	0.000	0.979	0.021
G37 Other demyelinating diseases of central nervous system	0.000	0.979	0.020
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.020	0.980	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.980	0.020
M89.94 Disorder of bone, unspecified (Hand)	0.019	0.981	0.000
M89.9 Disorder of bone, unspecified	0.019	0.981	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.019	0.981	0.000
N48.9 Disorder of penis, unspecified	0.019	0.981	0.000
S62.2 Fracture of first metacarpal bone	0.019	0.981	0.000
I84.6 Residual haemorrhoidal skin tags	0.000	0.981	0.019
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.981	0.018
Z99.1 Dependence on respirator	0.018	0.982	0.000
J38.3 Other diseases of vocal cords	0.000	0.982	0.018
K76.5 Hepatic veno-occlusive disease	0.000	0.982	0.018
K76.4 Peliosis hepatis	0.000	0.982	0.018
K76.2 Central haemorrhagic necrosis of liver	0.000	0.982	0.018
J38.2 Nodules of vocal cords	0.000	0.982	0.018
K76.1 Chronic passive congestion of liver	0.000	0.982	0.018
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.018	0.982	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.018	0.982	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.018	0.982	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.018	0.982	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.018	0.982	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.018	0.982	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.018	0.982	0.000
M89 Other disorders of bone	0.018	0.982	0.000
K70 Alcoholic liver disease	0.000	0.983	0.017
J38.7 Other diseases of larynx	0.000	0.983	0.017
M89.0 Algoneurodystrophy	0.016	0.984	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.984	0.016
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.016	0.984	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.016	0.984	0.000
K76.3 Infarction of liver	0.000	0.984	0.016
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.984	0.015
K76.7 Hepatorenal syndrome	0.000	0.984	0.015
J38.1 Polyp of vocal cord and larynx	0.000	0.985	0.015
M89.92 Disorder of bone, unspecified (Upper arm)	0.015	0.985	0.000
N48.2 Other inflammatory disorders of penis	0.015	0.985	0.000
K70.1 Alcoholic hepatitis	0.000	0.985	0.015
G37.5 Concentric sclerosis [Balo]	0.000	0.985	0.015
G37.4 Subacute necrotising myelitis	0.000	0.985	0.015
G37.2 Central pontine myelinolysis	0.000	0.985	0.015
G37.1 Central demyelination of corpus callosum	0.000	0.985	0.015
G37.0 Diffuse sclerosis	0.000	0.985	0.015
E70-E90 Metabolic disorders	0.000	0.985	0.015
M89.07 Algoneurodystrophy (Ankle and foot)	0.015	0.985	0.000
K76.9 Liver disease, unspecified	0.000	0.985	0.015
N48.0 Leukoplakia of penis	0.015	0.985	0.000
J38.5 Laryngeal spasm	0.000	0.985	0.015
M84.1 Nonunion of fracture [pseudarthrosis]	0.015	0.985	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.014	0.986	0.000
M89.5 Osteolysis	0.014	0.986	0.000
M89.3 Hypertrophy of bone	0.014	0.986	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.014	0.986	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.014	0.986	0.000
M20.0 Deformity of finger(s)	0.014	0.986	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.014	0.986	0.000
M89.03 Algoneurodystrophy (Forearm)	0.014	0.986	0.000
S62.21 Fracture of first metacarpal bone (open)	0.014	0.986	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.986	0.013
K93.1 Megacolon in Chagas' disease	0.000	0.986	0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.986	0.013
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.013	0.987	0.000
M84 Disorders of continuity of bone	0.013	0.987	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.987	0.013
M89.4 Other hypertrophic osteo-arthropathy	0.013	0.987	0.000
J38.6 Stenosis of larynx	0.000	0.987	0.013
E04.1 Non-toxic single thyroid nodule	0.001	0.987	0.013
M62.8 Other specified disorders of muscle	0.013	0.987	0.000
M94.88 Other specified disorders of cartilage (Other)	0.013	0.987	0.000
K11 Diseases of salivary glands	0.013	0.987	0.000
M89.6 Osteopathy after poliomyelitis	0.013	0.987	0.000
M89.2 Other disorders of bone development and growth	0.013	0.987	0.000
M89.1 Epiphyseal arrest	0.013	0.987	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.013	0.987	0.000
M62 Other disorders of muscle	0.013	0.987	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.987	0.013
M89.8 Other specified disorders of bone	0.013	0.987	0.000
M21.3 Wrist or foot drop (acquired)	0.013	0.987	0.000
M89.04 Algoneurodystrophy (Hand)	0.013	0.987	0.000
K11.2 Sialoadenitis	0.013	0.987	0.000
M20.5 Other deformities of toe(s) (acquired)	0.013	0.987	0.000
M89.98 Disorder of bone, unspecified (Other)	0.012	0.987	0.000
M62.88 Other specified disorders of muscle (Other)	0.012	0.987	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.012	0.988	0.000
M80-M85 Disorders of bone density and structure	0.012	0.988	0.000
M45-M49 Spondylopathies	0.012	0.988	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.012	0.988	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.988	0.012
M89.08 Algoneurodystrophy (Other)	0.012	0.988	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.012	0.988	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.012	0.988	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.012	0.988	0.000
M82 Osteoporosis in diseases classified elsewhere	0.012	0.988	0.000
M82.1 Osteoporosis in endocrine disorders	0.012	0.988	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.012	0.988	0.000
M86-M90 Other osteopathies	0.012	0.988	0.000
K70.0 Alcoholic fatty liver	0.000	0.988	0.012
M89.09 Algoneurodystrophy (Site unspecified)	0.012	0.988	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.988	0.011
M60-M63 Disorders of muscles	0.012	0.988	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.011	0.989	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.011	0.989	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.011	0.989	0.000
M84.2 Delayed union of fracture	0.011	0.989	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.011	0.989	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.989	0.011
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.011	0.989	0.000
K11.7 Disturbances of salivary secretion	0.011	0.989	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.011	0.989	0.000
E40-E46 Malnutrition	0.000	0.989	0.011
M94.8 Other specified disorders of cartilage	0.011	0.989	0.000
M85 Other disorders of bone density and structure	0.011	0.989	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.011	0.989	0.000
E76 Disorders of glycosaminoglycan metabolism	0.000	0.989	0.011
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.989	0.011
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.989	0.011
H34.8 Other retinal vascular occlusions	0.000	0.989	0.011
E84 Cystic fibrosis	0.000	0.989	0.011
M89.56 Osteolysis (Lower leg)	0.011	0.989	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.011	0.989	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.011	0.989	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.011	0.989	0.000
M89.38 Hypertrophy of bone (Other)	0.011	0.989	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.011	0.989	0.000
M62.4 Contracture of muscle	0.011	0.989	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.990	0.010
M62.83 Other specified disorders of muscle (Forearm)	0.010	0.990	0.000
M89.59 Osteolysis (Site unspecified)	0.010	0.990	0.000
M89.58 Osteolysis (Other)	0.010	0.990	0.000
M89.57 Osteolysis (Ankle and foot)	0.010	0.990	0.000
M89.54 Osteolysis (Hand)	0.010	0.990	0.000
M89.53 Osteolysis (Forearm)	0.010	0.990	0.000
M89.52 Osteolysis (Upper arm)	0.010	0.990	0.000
M89.51 Osteolysis (Shoulder region)	0.010	0.990	0.000
M89.50 Osteolysis (Multiple sites)	0.010	0.990	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.010	0.990	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.010	0.990	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.010	0.990	0.000
M89.34 Hypertrophy of bone (Hand)	0.010	0.990	0.000
M89.33 Hypertrophy of bone (Forearm)	0.010	0.990	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.010	0.990	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.010	0.990	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.010	0.990	0.000
M84.3 Stress fracture, not elsewhere classified	0.010	0.990	0.000
E70 Disorders of aromatic amino-acid metabolism	0.000	0.990	0.010
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.010	0.990	0.000
N48.8 Other specified disorders of penis	0.010	0.990	0.000
M91-M94 Chondropathies	0.010	0.990	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.990	0.010
M94 Other disorders of cartilage	0.010	0.990	0.000
M62.6 Muscle strain	0.010	0.990	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.990	0.010
K11.9 Disease of salivary gland, unspecified	0.010	0.990	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.010	0.990	0.000
E77 Disorders of glycoprotein metabolism	0.000	0.990	0.010
M62.0 Diastasis of muscle	0.010	0.990	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.990	0.010
E89.1 Postprocedural hypoinsulinaemia	0.000	0.990	0.010
M89.00 Algoneurodystrophy (Multiple sites)	0.010	0.990	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.990	0.010
M84.9 Disorder of continuity of bone, unspecified	0.010	0.990	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.010	0.990	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.990	0.010
E89.5 Postprocedural testicular hypofunction	0.000	0.990	0.010
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.010	0.990	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.010	0.990	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.010	0.990	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.010	0.990	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.010	0.990	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.010	0.990	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.010	0.990	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.010	0.990	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.010	0.990	0.000
M49 Spondylopathies in diseases classified elsewhere	0.010	0.990	0.000
E72 Other disorders of amino-acid metabolism	0.000	0.990	0.010
M62.87 Other specified disorders of muscle (Ankle and foot)	0.010	0.990	0.000
K11.4 Fistula of salivary gland	0.010	0.990	0.000
K11.0 Atrophy of salivary gland	0.010	0.990	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.010	0.990	0.000
M85.6 Other cyst of bone	0.010	0.990	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.010	0.990	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.990	0.009
M89.19 Epiphyseal arrest (Site unspecified)	0.009	0.990	0.000
M89.18 Epiphyseal arrest (Other)	0.009	0.990	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.009	0.990	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.009	0.990	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.009	0.990	0.000
M89.14 Epiphyseal arrest (Hand)	0.009	0.990	0.000
M89.13 Epiphyseal arrest (Forearm)	0.009	0.990	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.009	0.990	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.009	0.990	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.009	0.990	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.009	0.990	0.000
M89.28 Other disorders of bone development and growth (Other)	0.009	0.990	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.009	0.990	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.009	0.990	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.009	0.990	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.009	0.990	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.009	0.990	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.009	0.990	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.009	0.990	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.009	0.990	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.009	0.990	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.009	0.990	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.009	0.990	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.009	0.990	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.009	0.990	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.009	0.990	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.009	0.990	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.009	0.990	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.009	0.990	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.009	0.990	0.000
M99 Biomechanical lesions, not elsewhere classified	0.010	0.990	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.009	0.990	0.000
M84.8 Other disorders of continuity of bone	0.009	0.990	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.009	0.990	0.000
M62.3 Immobility syndrome (paraplegic)	0.009	0.990	0.000
M84.0 Malunion of fracture	0.009	0.990	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.009	0.991	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.009	0.991	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.009	0.991	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.009	0.991	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.009	0.991	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.009	0.991	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.009	0.991	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.009	0.991	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.009	0.991	0.000
M47.82 Other spondylosis (Cervical region)	0.009	0.991	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.009	0.991	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.009	0.991	0.000
M62.2 Ischaemic infarction of muscle	0.009	0.991	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.991	0.009
M62.81 Other specified disorders of muscle (Shoulder region)	0.009	0.991	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.009	0.991	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.009	0.991	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.991	0.009
K11.1 Hypertrophy of salivary gland	0.009	0.991	0.000
M85.4 Solitary bone cyst	0.009	0.991	0.000
C50.8 Overlapping lesion of breast	0.009	0.991	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.991	0.009
M35 Other systemic involvement of connective tissue	0.001	0.991	0.008
K11.3 Abscess of salivary gland	0.009	0.991	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.009	0.991	0.000
M62.46 Contracture of muscle (Lower leg)	0.009	0.991	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.009	0.991	0.000
K11.6 Mucocele of salivary gland	0.009	0.991	0.000
K70.4 Alcoholic hepatic failure	0.000	0.991	0.009
M00-M03 Infectious arthropathies	0.009	0.991	0.000
M83 Adult osteomalacia	0.009	0.991	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.009	0.991	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.009	0.991	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.009	0.991	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.009	0.991	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.009	0.991	0.000
M85.2 Hyperostosis of skull	0.009	0.991	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.009	0.991	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.009	0.991	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.009	0.991	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.009	0.991	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.009	0.991	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.009	0.991	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.009	0.991	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.009	0.991	0.000
M84.4 Pathological fracture, not elsewhere classified	0.009	0.991	0.000
M62.9 Disorder of muscle, unspecified	0.009	0.991	0.000
M92 Other juvenile osteochondrosis	0.009	0.991	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.008	0.991	0.000
M89.88 Other specified disorders of bone (Other)	0.008	0.991	0.000
M85.8 Other specified disorders of bone density and structure	0.009	0.991	0.000
E89.4 Postprocedural ovarian failure	0.000	0.991	0.008
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.009	0.991	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.008	0.991	0.000
M61 Calcification and ossification of muscle	0.008	0.991	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.008	0.991	0.000
M85.9 Disorder of bone density and structure, unspecified	0.008	0.991	0.000
M84.26 Delayed union of fracture (Lower leg)	0.008	0.991	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.991	0.008
M92.7 Juvenile osteochondrosis of metatarsus	0.008	0.991	0.000
M40-M43 Deforming dorsopathies	0.008	0.992	0.000
M62.84 Other specified disorders of muscle (Hand)	0.008	0.992	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.008	0.992	0.000
M21 Other acquired deformities of limbs	0.008	0.992	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.008	0.992	0.000
M87 Osteonecrosis	0.008	0.992	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.008	0.992	0.000
M84.28 Delayed union of fracture (Other)	0.008	0.992	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.008	0.992	0.000
M84.24 Delayed union of fracture (Hand)	0.008	0.992	0.000
M84.23 Delayed union of fracture (Forearm)	0.008	0.992	0.000
M84.22 Delayed union of fracture (Upper arm)	0.008	0.992	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.008	0.992	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.008	0.992	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
M89.84 Other specified disorders of bone (Hand)	0.008	0.992	0.000
M89.83 Other specified disorders of bone (Forearm)	0.008	0.992	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.992	0.008
E45 Retarded development following protein-energy malnutrition	0.000	0.992	0.008
E43 Unspecified severe protein-energy malnutrition	0.000	0.992	0.008
E42 Marasmic kwashiorkor	0.000	0.992	0.008
E41 Nutritional marasmus	0.000	0.992	0.008
E40 Kwashiorkor	0.000	0.992	0.008
M84.02 Malunion of fracture (Upper arm)	0.008	0.992	0.000
M85.64 Other cyst of bone (Hand)	0.008	0.992	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.008	0.992	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.008	0.992	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.008	0.992	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.008	0.992	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.008	0.992	0.000
M85.5 Aneurysmal bone cyst	0.008	0.992	0.000
M85.3 Osteitis condensans	0.008	0.992	0.000
M85.1 Skeletal fluorosis	0.008	0.992	0.000
M21.2 Flexion deformity	0.008	0.992	0.000
E71.3 Disorders of fatty-acid metabolism	0.000	0.992	0.008
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.992	0.008
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.992	0.008
E71.0 Maple-syrup-urine disease	0.000	0.992	0.008
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.992	0.008
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.992	0.008
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.992	0.008
E76.2 Other mucopolysaccharidoses	0.000	0.992	0.008
E76.1 Mucopolysaccharidosis, type II	0.000	0.992	0.008
E76.0 Mucopolysaccharidosis, type I	0.000	0.992	0.008
M99.8 Other biomechanical lesions	0.008	0.992	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations