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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs365053
log Bayes Factor = 58.5247
Chromosome 6   position 32,195,988  (GRCh37) Explore rs365053 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.010 0.990
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.011 0.989
E03 Other hypothyroidism
0.000 0.013 0.987
M06 Other rheumatoid arthritis
0.000 0.014 0.986
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.017 0.983
E03.9 Hypothyroidism, unspecified
0.000 0.017 0.983
E10.4 With neurological complications
0.000 0.019 0.981
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.023 0.977
K90.0 Coeliac disease
0.000 0.027 0.973
E10.2 With renal complications
0.000 0.035 0.965
E14.3 With ophthalmic complications
0.000 0.036 0.964
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.049 0.951
M06.3 Rheumatoid nodule
0.000 0.060 0.940
L40.9 Psoriasis, unspecified
0.000 0.060 0.940
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.064 0.936
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.072 0.928
E10.5 With peripheral circulatory complications
0.000 0.080 0.920
H36.0 Diabetic retinopathy
0.000 0.083 0.917
E14.9 Without complications
0.000 0.089 0.911
E10.0 With coma
0.000 0.092 0.908
E50-E64 Other nutritional deficiencies
0.000 0.096 0.904
M05-M14 Inflammatory polyarthropathies
0.000 0.136 0.864
M05 Seropositive rheumatoid arthritis
0.000 0.138 0.862
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.139 0.861
E06 Thyroiditis
0.000 0.139 0.861
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.141 0.859
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.156 0.844
E10.6 With other specified complications
0.000 0.167 0.833
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.167 0.833
M06.4 Inflammatory polyarthropathy
0.000 0.176 0.824
M06.34 Rheumatoid nodule (Hand)
0.000 0.183 0.817
E04 Other non-toxic goitre
0.000 0.187 0.813
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.196 0.804
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.199 0.801
E05.9 Thyrotoxicosis, unspecified
0.000 0.205 0.795
E06.3 Autoimmune thyroiditis
0.000 0.219 0.781
E53 Deficiency of other B group vitamins
0.000 0.220 0.780
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.224 0.776
E55 Vitamin D deficiency
0.000 0.225 0.775
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.236 0.764
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.243 0.757
M06.0 Seronegative rheumatoid arthritis
0.000 0.244 0.756
E07 Other disorders of thyroid
0.000 0.252 0.748
E10.8 With unspecified complications
0.000 0.255 0.745
G37 Other demyelinating diseases of central nervous system
0.000 0.257 0.743
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.258 0.742
E14.1 With ketoacidosis
0.000 0.265 0.735
E14.8 With unspecified complications
0.000 0.277 0.723
E14.4 With neurological complications
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.290 0.709
E14.6 With other specified complications
0.000 0.290 0.709
E14.5 With peripheral circulatory complications
0.000 0.290 0.709
E14.0 With coma
0.000 0.290 0.709
E05.5 Thyroid crisis or storm
0.000 0.290 0.709
E05.4 Thyrotoxicosis factitia
0.000 0.290 0.709
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.290 0.709
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.290 0.709
E04.0 Non-toxic diffuse goitre
0.000 0.291 0.709
E03.5 Myxoedema coma
0.000 0.292 0.707
E03.4 Atrophy of thyroid (acquired)
0.000 0.292 0.707
E03.3 Postinfectious hypothyroidism
0.000 0.292 0.707
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.292 0.707
M06.8 Other specified rheumatoid arthritis
0.000 0.293 0.707
M06.2 Rheumatoid bursitis
0.000 0.293 0.707
M06.1 Adult-onset Still's disease
0.000 0.293 0.707
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.297 0.703
E61 Deficiency of other nutrient elements
0.000 0.298 0.702
E04.2 Non-toxic multinodular goitre
0.000 0.310 0.690
E55.9 Vitamin D deficiency, unspecified
0.000 0.318 0.682
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.326 0.674
M06.38 Rheumatoid nodule (Other)
0.000 0.326 0.674
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.326 0.674
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.326 0.674
M06.33 Rheumatoid nodule (Forearm)
0.000 0.326 0.674
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.326 0.674
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.326 0.674
E03.1 Congenital hypothyroidism without goitre
0.000 0.331 0.669
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.332 0.668
E53.9 Vitamin B deficiency, unspecified
0.000 0.335 0.665
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.340 0.660
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.342 0.658
E40-E46 Malnutrition
0.000 0.342 0.658
E05.8 Other thyrotoxicosis
0.000 0.347 0.653
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.352 0.648
E63 Other nutritional deficiencies
0.000 0.352 0.648
E56 Other vitamin deficiencies
0.000 0.352 0.648
E50 Vitamin A deficiency
0.000 0.352 0.648
E60 Dietary zinc deficiency
0.000 0.352 0.648
E59 Dietary selenium deficiency
0.000 0.352 0.648
E54 Ascorbic acid deficiency
0.000 0.352 0.648
E52 Niacin deficiency [pellagra]
0.000 0.352 0.648
H36 Retinal disorders in diseases classified elsewhere
0.000 0.355 0.644
E14.2 Withrenal complications
0.000 0.356 0.644
E07.8 Other specified disorders of thyroid
0.000 0.365 0.635
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.369 0.631
E51 Thiamine deficiency
0.000 0.374 0.626
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.375 0.625
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.380 0.620
M08 Juvenile arthritis
0.000 0.380 0.620
M05.8 Other seropositive rheumatoid arthritis
0.000 0.382 0.618
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.382 0.618
M05.2 Rheumatoid vasculitis
0.000 0.382 0.618
M05.1 Rheumatoid lung disease
0.000 0.382 0.618
M05.0 Felty's syndrome
0.000 0.382 0.618
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.383 0.617
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.383 0.617
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.383 0.617
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.383 0.617
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.383 0.617
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.383 0.617
E06.5 Other chronic thyroiditis
0.000 0.383 0.617
E06.4 Drug-induced thyroiditis
0.000 0.383 0.617
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.383 0.617
E06.1 Subacute thyroiditis
0.000 0.383 0.617
E06.0 Acute thyroiditis
0.000 0.383 0.617
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.389 0.610
E53.8 Deficiency of other specified B group vitamins
0.000 0.392 0.608
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.392 0.608
M14 Arthropathies in other diseases classified elsewhere
0.000 0.398 0.602
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.399 0.601
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.402 0.598
E61.1 Iron deficiency
0.000 0.402 0.598
M12 Other specific arthropathies
0.000 0.405 0.595
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.409 0.590
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.409 0.590
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.409 0.590
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.409 0.590
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.409 0.590
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.409 0.590
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.409 0.590
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.409 0.590
E16.1 Other hypoglycaemia
0.000 0.417 0.583
E04.8 Other specified non-toxic goitre
0.000 0.417 0.583
E70-E90 Metabolic disorders
0.000 0.418 0.582
E58 Dietary calcium deficiency
0.000 0.420 0.580
L40 Psoriasis
0.000 0.420 0.580
G36 Other acute disseminated demyelination
0.000 0.424 0.576
E03.8 Other specified hypothyroidism
0.000 0.427 0.573
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.429 0.571
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.433 0.566
E86 Volume depletion
0.000 0.438 0.562
E53.1 Pyridoxine deficiency
0.000 0.441 0.559
E53.0 Riboflavin deficiency
0.000 0.441 0.559
E06.9 Thyroiditis, unspecified
0.000 0.442 0.558
C85.1 B-cell lymphoma, unspecified
0.000 0.442 0.558
E55.0 Rickets, active
0.000 0.444 0.555
M10 Gout
0.000 0.451 0.549
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.457 0.542
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.457 0.542
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.457 0.542
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.457 0.542
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.457 0.542
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.457 0.542
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.459 0.541
E07.1 Dyshormogenetic goitre
0.000 0.463 0.536
E07.0 Hypersecretion of calcitonin
0.000 0.463 0.536
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.464 0.536
G37.5 Concentric sclerosis [Balo]
0.000 0.467 0.533
G37.4 Subacute necrotising myelitis
0.000 0.467 0.533
G37.2 Central pontine myelinolysis
0.000 0.467 0.533
G37.1 Central demyelination of corpus callosum
0.000 0.467 0.533
G37.0 Diffuse sclerosis
0.000 0.467 0.533
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.471 0.529
E73 Lactose intolerance
0.000 0.476 0.524
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.493 0.507
M06.18 Adult-onset Still's disease (Other)
0.000 0.493 0.507
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.493 0.507
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.493 0.507
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.493 0.507
M06.14 Adult-onset Still's disease (Hand)
0.000 0.493 0.507
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.493 0.507
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.493 0.507
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.493 0.507
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.493 0.507
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.493 0.507
M06.28 Rheumatoid bursitis (Other)
0.000 0.493 0.507
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.493 0.507
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.493 0.507
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.493 0.507
M06.24 Rheumatoid bursitis (Hand)
0.000 0.493 0.507
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.493 0.507
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.493 0.507
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.493 0.507
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.493 0.507
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.493 0.507
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.493 0.507
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.493 0.507
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.493 0.507
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.493 0.507
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.493 0.507
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.493 0.507
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.493 0.507
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.493 0.507
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.493 0.507
E13 Other specified diabetes mellitus
0.001 0.496 0.504
E61.9 Deficiency of nutrient element, unspecified
0.000 0.497 0.503
E61.8 Deficiency of other specified nutrient elements
0.000 0.497 0.503
E61.7 Deficiency of multiple nutrient elements
0.000 0.497 0.503
E61.6 Vanadium deficiency
0.000 0.497 0.503
E61.5 Molybdenum deficiency
0.000 0.497 0.503
E61.4 Chromium deficiency
0.000 0.497 0.503
E61.3 Manganese deficiency
0.000 0.497 0.503
E61.0 Copper deficiency
0.000 0.497 0.503
L40.5 Arthropathic psoriasis
0.000 0.516 0.484
E73.9 Lactose intolerance, unspecified
0.000 0.517 0.483
M11 Other crystal arthropathies
0.000 0.517 0.483
E04.9 Non-toxic goitre, unspecified
0.000 0.525 0.475
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.528 0.472
E45 Retarded development following protein-energy malnutrition
0.000 0.528 0.472
E43 Unspecified severe protein-energy malnutrition
0.000 0.528 0.472
E42 Marasmic kwashiorkor
0.000 0.528 0.472
E41 Nutritional marasmus
0.000 0.528 0.472
E40 Kwashiorkor
0.000 0.528 0.472
E50.9 Vitamin A deficiency, unspecified
0.000 0.535 0.465
E50.8 Other manifestations of vitamin A deficiency
0.000 0.535 0.465
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.535 0.465
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.535 0.465
E50.5 Vitamin A deficiency with night blindness
0.000 0.535 0.465
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.535 0.465
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.535 0.465
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.535 0.465
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.535 0.465
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.535 0.465
E56.9 Vitamin deficiency, unspecified
0.000 0.535 0.465
E56.8 Deficiency of other vitamins
0.000 0.535 0.465
E56.1 Deficiency of vitamin K
0.000 0.535 0.465
E56.0 Deficiency of vitamin E
0.000 0.535 0.465
E63.9 Nutritional deficiency, unspecified
0.000 0.535 0.465
E63.8 Other specified nutritional deficiencies
0.000 0.535 0.465
E63.1 Imbalance of constituents of food intake
0.000 0.535 0.465
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.535 0.465
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.535 0.465
E64.8 Sequelae of other nutritional deficiencies
0.000 0.535 0.465
E64.3 Sequelae of rickets
0.000 0.535 0.465
E64.2 Sequelae of vitamin C deficiency
0.000 0.535 0.465
E64.1 Sequelae of vitamin A deficiency
0.000 0.535 0.465
E64.0 Sequelae of protein-energy malnutrition
0.000 0.535 0.465
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.535 0.465
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.538 0.462
M07 Psoriatic and enteropathic arthropathies
0.000 0.540 0.459
E51.9 Thiamine deficiency, unspecified
0.000 0.551 0.449
E51.8 Other manifestations of thiamine deficiency
0.000 0.551 0.449
E51.1 Beriberi
0.000 0.551 0.449
H30-H36 Disorders of choroid and retina
0.000 0.551 0.449
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.552 0.448
M08.9 Juvenile arthritis, unspecified
0.000 0.556 0.444
M08.8 Other juvenile arthritis
0.000 0.556 0.444
M08.4 Pauciarticular juvenile arthritis
0.000 0.556 0.444
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.556 0.444
M08.2 Juvenile arthritis with systemic onset
0.000 0.556 0.444
M08.1 Juvenile ankylosing spondylitis
0.000 0.556 0.444
M08.0 Juvenile rheumatoid arthritis
0.000 0.556 0.444
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.556 0.444
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.556 0.444
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.556 0.444
M09.0 Juvenile arthritis in psoriasis
0.000 0.556 0.444
M05.09 Felty's syndrome (Site unspecified)
0.000 0.557 0.443
M05.08 Felty's syndrome (Other)
0.000 0.557 0.443
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.557 0.443
M05.06 Felty's syndrome (Lower leg)
0.000 0.557 0.443
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.557 0.443
M05.04 Felty's syndrome (Hand)
0.000 0.557 0.443
M05.03 Felty's syndrome (Forearm)
0.000 0.557 0.443
M05.02 Felty's syndrome (Upper arm)
0.000 0.557 0.443
M05.01 Felty's syndrome (Shoulder region)
0.000 0.557 0.443
M05.00 Felty's syndrome (Multiple sites)
0.000 0.557 0.443
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.557 0.443
M05.18 Rheumatoid lung disease (Other)
0.000 0.557 0.443
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.557 0.443
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.557 0.443
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.557 0.443
M05.14 Rheumatoid lung disease (Hand)
0.000 0.557 0.443
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.557 0.443
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.557 0.443
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.557 0.443
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.557 0.443
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.557 0.443
M05.28 Rheumatoid vasculitis (Other)
0.000 0.557 0.443
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.557 0.443
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.557 0.443
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.557 0.443
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.557 0.443
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.557 0.443
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.557 0.443
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.557 0.443
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.557 0.443
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.557 0.443
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.557 0.443
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.557 0.443
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.557 0.443
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.557 0.443
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.557 0.443
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.557 0.443
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.557 0.443
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.557 0.443
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.557 0.443
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.557 0.443
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.557 0.443
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.557 0.443
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.557 0.443
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.557 0.443
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.557 0.443
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.557 0.443
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.557 0.443
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.557 0.443
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.557 0.443
E88 Other metabolic disorders
0.000 0.558 0.441
M10.0 Idiopathic gout
0.000 0.560 0.440
E04.1 Non-toxic single thyroid nodule
0.000 0.561 0.439
L40.0 Psoriasis vulgaris
0.000 0.565 0.435
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.568 0.431
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.568 0.431
M14.4 Arthropathy in amyloidosis
0.000 0.568 0.431
M14.3 Lipoid dermatoarthritis
0.000 0.568 0.431
M14.2 Diabetic arthropathy
0.000 0.568 0.431
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.568 0.431
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.568 0.431
E89.0 Postprocedural hypothyroidism
0.000 0.569 0.431
H33 Retinal detachments and breaks
0.000 0.569 0.431
E11 Non-insulin-dependent diabetes mellitus
0.000 0.572 0.428
E51.2 Wernicke's encephalopathy
0.000 0.573 0.427
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.573 0.426
M12.5 Traumatic arthropathy
0.000 0.573 0.426
M12.4 Intermittent hydrarthrosis
0.000 0.573 0.426
M12.3 Palindromic rheumatism
0.000 0.573 0.426
M12.1 Kaschin-Beck disease
0.000 0.573 0.426
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.573 0.426
E61.2 Magnesium deficiency
0.000 0.576 0.423
K90 Intestinal malabsorption
0.000 0.578 0.422
E79 Disorders of purine and pyrimidine metabolism
0.000 0.581 0.419
H33.2 Serous retinal detachment
0.000 0.581 0.419
E77 Disorders of glycoprotein metabolism
0.000 0.583 0.417
E76 Disorders of glycosaminoglycan metabolism
0.000 0.583 0.417
E72 Other disorders of amino-acid metabolism
0.000 0.583 0.417
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.583 0.417
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.583 0.417
L40.3 Pustulosis palmaris et plantaris
0.000 0.584 0.416
L40.2 Acrodermatitis continua
0.000 0.584 0.416
E84 Cystic fibrosis
0.000 0.585 0.415
M13 Other arthritis
0.000 0.586 0.414
H33.3 Retinal breaks without detachment
0.000 0.586 0.414
M14.6 Neuropathic arthropathy
0.000 0.586 0.413
G36.9 Acute disseminated demyelination, unspecified
0.000 0.587 0.413
G36.8 Other specified acute disseminated demyelination
0.000 0.587 0.413
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.587 0.413
G36.0 Neuromyelitis optica [Devic]
0.000 0.587 0.413
E46 Unspecified protein-energy malnutrition
0.000 0.587 0.413
E07.9 Disorder of thyroid, unspecified
0.000 0.588 0.412
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.590 0.409
C85.0 Lymphosarcoma
0.000 0.590 0.409
L40.1 Generalised pustular psoriasis
0.000 0.591 0.409
M12.2 Villonodular synovitis (pigmented)
0.000 0.598 0.402
M10.4 Other secondary gout
0.000 0.606 0.394
M10.3 Gout due to impairment of renal function
0.000 0.606 0.394
M10.2 Drug-induced gout
0.000 0.606 0.394
M10.1 Lead-induced gout
0.000 0.606 0.394
E74 Other disorders of carbohydrate metabolism
0.000 0.609 0.391
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.618 0.382
E83 Disorders of mineral metabolism
0.000 0.618 0.382
E11.8 With unspecified complications
0.000 0.623 0.377
E73.8 Other lactose intolerance
0.000 0.624 0.376
E73.1 Secondary lactase deficiency
0.000 0.624 0.376
E73.0 Congenital lactase deficiency
0.000 0.624 0.376
E11.3 With ophthalmic complications
0.000 0.624 0.376
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.631 0.368
E70 Disorders of aromatic amino-acid metabolism
0.000 0.632 0.368
E20-E35 Disorders of other endocrine glands
0.000 0.635 0.365
E13.8 With unspecified complications
0.001 0.638 0.361
E13.7 With multiple complications
0.001 0.638 0.361
E13.6 With other specified complications
0.001 0.638 0.361
E13.5 With peripheral circulatory complications
0.001 0.638 0.361
E13.4 With neurological complications
0.001 0.638 0.361
E13.3 With ophthalmic complications
0.001 0.638 0.361
E13.2 With renal complications
0.001 0.638 0.361
E13.1 With ketoacidosis
0.001 0.638 0.361
E13.0 With coma
0.001 0.638 0.361
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.641 0.358
H30 Chorioretinal inflammation
0.000 0.642 0.358
E89.4 Postprocedural ovarian failure
0.000 0.642 0.358
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.643 0.357
E83.1 Disorders of iron metabolism
0.000 0.644 0.356
L40.8 Other psoriasis
0.000 0.644 0.356
E27 Other disorders of adrenal gland
0.000 0.646 0.354
E11.1 With ketoacidosis
0.000 0.646 0.354
E27.1 Primary adrenocortical insufficiency
0.000 0.651 0.349
M11.8 Other specified crystal arthropathies
0.000 0.653 0.347
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.653 0.347
M11.1 Familial chondrocalcinosis
0.000 0.653 0.346
M11.0 Hydroxyapatite deposition disease
0.000 0.653 0.346
L40.4 Guttate psoriasis
0.000 0.654 0.345
J33.0 Polyp of nasal cavity
0.000 0.659 0.341
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.661 0.339
E44.1 Mild protein-energy malnutrition
0.000 0.661 0.338
E44.0 Moderate protein-energy malnutrition
0.000 0.661 0.338
M13.8 Other specified arthritis
0.000 0.663 0.337
J33 Nasal polyp
0.000 0.663 0.337
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.667 0.333
E89.5 Postprocedural testicular hypofunction
0.000 0.667 0.333
E89.1 Postprocedural hypoinsulinaemia
0.000 0.667 0.333
L40-L45 Papulosquamous disorders
0.000 0.667 0.333
E88.8 Other specified metabolic disorders
0.000 0.670 0.330
M07.6 Other enteropathic arthropathies
0.000 0.670 0.329
M07.5 Arthropathy in ulcerative colitis
0.000 0.670 0.329
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.670 0.329
M07.2 Psoriatic spondylitis
0.000 0.670 0.329
M07.1 Arthritis mutilans
0.000 0.670 0.329
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.670 0.329
H33.4 Traction detachment of retina
0.000 0.670 0.330
E89.3 Postprocedural hypopituitarism
0.000 0.673 0.327
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.678 0.322
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.000 0.681 0.319
M08.08 Juvenile rheumatoid arthritis (Other)
0.000 0.681 0.319
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.000 0.681 0.319
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.000 0.681 0.319
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.000 0.681 0.319
M08.04 Juvenile rheumatoid arthritis (Hand)
0.000 0.681 0.319
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.000 0.681 0.319
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.000 0.681 0.319
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.000 0.681 0.319
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.000 0.681 0.319
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.000 0.681 0.319
M08.18 Juvenile ankylosing spondylitis (Other)
0.000 0.681 0.319
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.000 0.681 0.319
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.000 0.681 0.319
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.000 0.681 0.319
M08.14 Juvenile ankylosing spondylitis (Hand)
0.000 0.681 0.319
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.000 0.681 0.319
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.000 0.681 0.319
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.000 0.681 0.319
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.000 0.681 0.319
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.000 0.681 0.319
M08.28 Juvenile arthritis with systemic onset (Other)
0.000 0.681 0.319
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.000 0.681 0.319
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.000 0.681 0.319
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.000 0.681 0.319
M08.24 Juvenile arthritis with systemic onset (Hand)
0.000 0.681 0.319
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.000 0.681 0.319
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.000 0.681 0.319
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.000 0.681 0.319
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.000 0.681 0.319
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.000 0.681 0.319
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.000 0.681 0.319
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.000 0.681 0.319
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.000 0.681 0.319
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.000 0.681 0.319
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.000 0.681 0.319
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.000 0.681 0.319
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.000 0.681 0.319
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.000 0.681 0.319
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.000 0.681 0.319
M08.49 Pauciarticular juvenile arthritis (Site unspecified)
0.000 0.681 0.319
M08.48 Pauciarticular juvenile arthritis (Other)
0.000 0.681 0.319
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)
0.000 0.681 0.319
M08.46 Pauciarticular juvenile arthritis (Lower leg)
0.000 0.681 0.319
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)
0.000 0.681 0.319
M08.44 Pauciarticular juvenile arthritis (Hand)
0.000 0.681 0.319
M08.43 Pauciarticular juvenile arthritis (Forearm)
0.000 0.681 0.319
M08.42 Pauciarticular juvenile arthritis (Upper arm)
0.000 0.681 0.319

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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