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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3734543
log Bayes Factor = 141.479
Chromosome 6   position 26,468,545  (GRCh37) Explore rs3734543 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E03 Other hypothyroidism
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
M17 Gonarthrosis [arthrosis of knee]
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
M17.9 Gonarthrosis, unspecified
0.999 0.001 0.000
K90 Intestinal malabsorption
0.999 0.001 0.000
N40 Hyperplasia of prostate
0.000 0.002 0.998
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.002 0.998
Chapter XI Diseases of the digestive system
0.996 0.002 0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.995 0.003 0.002
K70-K77 Diseases of liver
0.996 0.004 0.000
E16 Other disorders of pancreatic internal secretion
0.995 0.005 0.000
M06 Other rheumatoid arthritis
0.995 0.005 0.000
K40 Inguinal hernia
0.000 0.005 0.995
K75 Other inflammatory liver diseases
0.995 0.005 0.000
K44 Diaphragmatic hernia
0.000 0.005 0.994
K40-K46 Hernia
0.001 0.006 0.992
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
M06.9 Rheumatoid arthritis, unspecified
0.993 0.007 0.000
K75.4 Autoimmune hepatitis
0.992 0.008 0.000
E20-E35 Disorders of other endocrine glands
0.990 0.010 0.000
E27 Other disorders of adrenal gland
0.990 0.010 0.000
M35 Other systemic involvement of connective tissue
0.989 0.011 0.000
E27.1 Primary adrenocortical insufficiency
0.989 0.011 0.000
M31 Other necrotising vasculopathies
0.989 0.011 0.000
S40-S49 Injuries to the shoulder and upper arm
0.986 0.014 0.000
E10.3 With ophthalmic complications
0.985 0.015 0.000
H34 Retinal vascular occlusions
0.982 0.018 0.000
D80-D89 Certain disorders involving the immune mechanism
0.981 0.019 0.000
M35.0 Sicca syndrome [Sjogren]
0.981 0.019 0.000
H25-H28 Disorders of lens
0.980 0.020 0.000
H35 Other retinal disorders
0.980 0.020 0.000
M31.6 Other giant cell arteritis
0.977 0.023 0.000
H35.8 Other specified retinal disorders
0.975 0.025 0.000
S00-S09 Injuries to the head
0.974 0.026 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.973 0.027 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.972 0.028 0.000
N40-N51 Diseases of male genital organs
0.000 0.031 0.969
H26 Other cataract
0.967 0.033 0.000
H43-H45 Disorders of vitreous body and globe
0.965 0.035 0.000
M23 Internal derangement of knee
0.964 0.036 0.000
M34 Systemic sclerosis
0.963 0.037 0.000
S90-S99 Injuries to the ankle and foot
0.963 0.037 0.000
N42 Other disorders of prostate
0.000 0.037 0.963
H26.9 Cataract, unspecified
0.962 0.038 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.958 0.042 0.000
M17.0 Primary gonarthrosis, bilateral
0.958 0.042 0.000
D50-D53 Nutritional anaemias
0.955 0.045 0.000
M22 Disorders of patella
0.955 0.045 0.000
D86 Sarcoidosis
0.952 0.048 0.000
E10.2 With renal complications
0.951 0.049 0.000
N30-N39 Other diseases of urinary system
0.000 0.051 0.949
M18 Arthrosis of first carpometacarpal joint
0.949 0.051 0.000
N32 Other disorders of bladder
0.000 0.052 0.948
N32.0 Bladder-neck obstruction
0.000 0.053 0.947
E50-E64 Other nutritional deficiencies
0.943 0.057 0.000
M07 Psoriatic and enteropathic arthropathies
0.943 0.057 0.000
H43 Disorders of vitreous body
0.943 0.057 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.942 0.058 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.939 0.061 0.000
M10 Gout
0.937 0.063 0.000
S09 Other and unspecified injuries of head
0.936 0.064 0.000
D50 Iron deficiency anaemia
0.935 0.065 0.000
N39 Other disorders of urinary system
0.000 0.065 0.935
H46-H48 Disorders of optic nerve and visual pathways
0.934 0.066 0.000
L20-L30 Dermatitis and eczema
0.930 0.070 0.000
H36 Retinal disorders in diseases classified elsewhere
0.930 0.070 0.000
N42.8 Other specified disorders of prostate
0.000 0.073 0.927
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.924 0.076 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.923 0.077 0.000
E10.1 With ketoacidosis
0.922 0.078 0.000
H34.8 Other retinal vascular occlusions
0.920 0.080 0.000
H43.1 Vitreous haemorrhage
0.919 0.081 0.000
K75.8 Other specified inflammatory liver diseases
0.918 0.082 0.000
M23.3 Other meniscus derangements
0.918 0.082 0.000
D50.9 Iron deficiency anaemia, unspecified
0.918 0.082 0.000
D86.9 Sarcoidosis, unspecified
0.918 0.082 0.000
K72 Hepatic failure, not elsewhere classified
0.916 0.084 0.000
M24 Other specific joint derangements
0.916 0.084 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.915 0.085 0.000
S09.9 Unspecified injury of head
0.913 0.087 0.000
M60-M63 Disorders of muscles
0.913 0.087 0.000
L30 Other dermatitis
0.912 0.088 0.000
K73 Chronic hepatitis, not elsewhere classified
0.912 0.088 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.093 0.907
Chapter XX External causes of morbidity and mortality
0.906 0.094 0.000
M07.3 Other psoriatic arthropathies
0.903 0.097 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.902 0.098 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.902 0.098 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.901 0.099 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.100 0.900
M11 Other crystal arthropathies
0.900 0.100 0.000
S80-S89 Injuries to the knee and lower leg
0.900 0.100 0.000
K75.9 Inflammatory liver disease, unspecified
0.899 0.101 0.000
M17.1 Other primary gonarthrosis
0.897 0.103 0.000
Chapter XIV Diseases of the genitourinary system
0.000 0.104 0.896
L30.9 Dermatitis, unspecified
0.895 0.105 0.000
E14 Unspecified diabetes mellitus
0.895 0.105 0.000
H34.2 Other retinal artery occlusions
0.892 0.108 0.000
E53 Deficiency of other B group vitamins
0.889 0.111 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.888 0.112 0.000
M22.3 Other derangements of patella
0.886 0.114 0.000
W00-W19 Falls
0.886 0.114 0.000
H36.0 Diabetic retinopathy
0.880 0.120 0.000
N39.8 Other specified disorders of urinary system
0.000 0.121 0.879
S49.9 Unspecified injury of shoulder and upper arm
0.878 0.122 0.000
T79-T79 Certain early complications of trauma
0.876 0.124 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.875 0.125 0.000
H02 Other disorders of eyelid
0.873 0.127 0.000
M25 Other joint disorders, not elsewhere classified
0.873 0.127 0.000
S02 Fracture of skull and facial bones
0.872 0.128 0.000
S93.1 Dislocation of toe(s)
0.871 0.129 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.870 0.130 0.000
E70-E90 Metabolic disorders
0.869 0.131 0.000
E11 Non-insulin-dependent diabetes mellitus
0.869 0.131 0.000
S20-S29 Injuries to the thorax
0.867 0.133 0.000
S92 Fracture of foot, except ankle
0.866 0.134 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.863 0.137 0.000
M34.9 Systemic sclerosis, unspecified
0.862 0.138 0.000
S80 Superficial injury of lower leg
0.862 0.138 0.000
H27 Other disorders of lens
0.861 0.139 0.000
L50-L54 Urticaria and erythema
0.860 0.140 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.859 0.141 0.000
N34 Urethritis and urethral syndrome
0.000 0.141 0.859
Q38-Q45 Other congenital malformations of the digestive system
0.858 0.142 0.000
M34.1 CR(E)ST syndrome
0.858 0.142 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.855 0.145 0.000
E10.4 With neurological complications
0.853 0.147 0.000
H02.1 Ectropion of eyelid
0.852 0.148 0.000
M62 Other disorders of muscle
0.851 0.149 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.847 0.153 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.153 0.847
N32.8 Other specified disorders of bladder
0.000 0.154 0.846
E53.8 Deficiency of other specified B group vitamins
0.845 0.155 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.841 0.159 0.000
K90.9 Intestinal malabsorption, unspecified
0.840 0.160 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.840 0.160 0.000
T00-T07 Injuries involving multiple body regions
0.837 0.163 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.836 0.164 0.000
M14 Arthropathies in other diseases classified elsewhere
0.836 0.164 0.000
M70-M79 Other soft tissue disorders
0.836 0.164 0.000
M25.7 Osteophyte
0.836 0.164 0.000
S05 Injury of eye and orbit
0.836 0.164 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.832 0.168 0.000
H02.6 Xanthelasma of eyelid
0.832 0.168 0.000
N30 Cystitis
0.000 0.168 0.832
E10.5 With peripheral circulatory complications
0.831 0.169 0.000
M10.9 Gout, unspecified
0.831 0.169 0.000
D55-D59 Haemolytic anaemias
0.830 0.170 0.000
M24.1 Other articular cartilage disorders
0.830 0.170 0.000
M11.2 Other chondrocalcinosis
0.828 0.172 0.000
N48 Other disorders of penis
0.000 0.172 0.828
M10.0 Idiopathic gout
0.825 0.175 0.000
L27 Dermatitis due to substances taken internally
0.824 0.176 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.824 0.176 0.000
E23 Hypofunction and other disorders of pituitary gland
0.823 0.177 0.000
W19 Unspecified fall
0.823 0.177 0.000
E11.5 With peripheral circulatory complications
0.822 0.178 0.000
Chapter II Neoplasms
0.821 0.179 0.000
M72 Fibroblastic disorders
0.821 0.179 0.000
H26.4 After-cataract
0.820 0.180 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.820 0.180 0.000
H02.5 Other disorders affecting eyelid function
0.819 0.181 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.818 0.182 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.817 0.183 0.000
S92.3 Fracture of metatarsal bone
0.816 0.184 0.000
M23.0 Cystic meniscus
0.814 0.186 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.813 0.187 0.000
S93.0 Dislocation of ankle joint
0.813 0.187 0.000
H05 Disorders of orbit
0.812 0.188 0.000
H31 Other disorders of choroid
0.812 0.188 0.000
E10.8 With unspecified complications
0.811 0.189 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.811 0.189 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.811 0.189 0.000
D50.8 Other iron deficiency anaemias
0.810 0.190 0.000
S80.0 Contusion of knee
0.810 0.190 0.000
H46 Optic neuritis
0.809 0.191 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.809 0.191 0.000
M23.9 Internal derangement of knee, unspecified
0.807 0.193 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.807 0.193 0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level
0.807 0.193 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.805 0.195 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.805 0.195 0.000
Q50-Q56 Congenital malformations of genital organs
0.804 0.196 0.000
M25.76 Osteophyte (Lower leg)
0.803 0.197 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.802 0.198 0.000
E14.3 With ophthalmic complications
0.800 0.200 0.000
E10.6 With other specified complications
0.800 0.200 0.000
K72.0 Acute and subacute hepatic failure
0.798 0.202 0.000
N39.9 Disorder of urinary system, unspecified
0.000 0.202 0.798
S02.4 Fracture of malar and maxillary bones
0.798 0.202 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.797 0.203 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.797 0.203 0.000
S46.3 Injury of muscle and tendon of triceps
0.797 0.203 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.796 0.204 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.795 0.205 0.000
D86.0 Sarcoidosis of lung
0.795 0.205 0.000
M22.8 Other disorders of patella
0.795 0.205 0.000
D84 Other immunodeficiencies
0.794 0.206 0.000
L28 Lichen simplex chronicus and prurigo
0.793 0.207 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.792 0.208 0.000
N36 Other disorders of urethra
0.000 0.208 0.792
K72.9 Hepatic failure, unspecified
0.791 0.209 0.000
N32.1 Vesicointestinal fistula
0.000 0.210 0.790
T79 Certain early complications of trauma, not elsewhere classified
0.789 0.211 0.000
S21 Open wound of thorax
0.789 0.211 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.212 0.788
L52 Erythema nodosum
0.788 0.212 0.000
E27.2 Addisonian crisis
0.787 0.213 0.000
E11.3 With ophthalmic complications
0.787 0.213 0.000
N34.2 Other urethritis
0.000 0.215 0.785
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.785 0.215 0.000
M00-M03 Infectious arthropathies
0.782 0.218 0.000
S92.30 Fracture of metatarsal bone (closed)
0.780 0.220 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.220 0.780
L10-L14 Bullous disorders
0.780 0.220 0.000
H30 Chorioretinal inflammation
0.779 0.221 0.000
M34.8 Other forms of systemic sclerosis
0.779 0.221 0.000
H26.1 Traumatic cataract
0.778 0.222 0.000
S80.8 Other superficial injuries of lower leg
0.777 0.223 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.777 0.223 0.000
E20 Hypoparathyroidism
0.777 0.223 0.000
N39.3 Stress incontinence
0.000 0.224 0.776
M24.4 Recurrent dislocation and subluxation of joint
0.774 0.226 0.000
W07 Fall involving chair
0.774 0.226 0.000
N30.2 Other chronic cystitis
0.000 0.227 0.773
M25.9 Joint disorder, unspecified
0.773 0.227 0.000
M62.8 Other specified disorders of muscle
0.773 0.227 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.772 0.227 0.000
S46.1 Injury of muscle and tendon of long head of biceps
0.772 0.228 0.000
E61 Deficiency of other nutrient elements
0.769 0.231 0.000
D83 Common variable immunodeficiency
0.767 0.233 0.000
M25.71 Osteophyte (Shoulder region)
0.766 0.234 0.000
V20-V29 Motorcycle rider injured in transport accident
0.766 0.234 0.000
M65-M68 Disorders of synovium and tendon
0.765 0.235 0.000
C81 Hodgkin's disease
0.764 0.236 0.000
X20-X29 Contact with venomous animals and plants
0.763 0.237 0.000
D61 Other aplastic anaemias
0.763 0.237 0.000
H34.1 Central retinal artery occlusion
0.760 0.240 0.000
M06.4 Inflammatory polyarthropathy
0.760 0.240 0.000
L40-L45 Papulosquamous disorders
0.760 0.240 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.760 0.240 0.000
N48.1 Balanoposthitis
0.000 0.240 0.760
H27.0 Aphakia
0.760 0.240 0.000
H34.9 Retinal vascular occlusion, unspecified
0.758 0.242 0.000
M15 Polyarthrosis
0.758 0.242 0.000
M13 Other arthritis
0.758 0.242 0.000
N30.3 Trigonitis
0.000 0.243 0.757
N48.4 Impotence of organic origin
0.000 0.244 0.756
E10.0 With coma
0.753 0.246 0.000
S02.3 Fracture of orbital floor
0.753 0.247 0.000
H43.8 Other disorders of vitreous body
0.752 0.248 0.000
M22.2 Patellofemoral disorders
0.751 0.249 0.000
M35.7 Hypermobility syndrome
0.751 0.249 0.000
L50 Urticaria
0.750 0.250 0.000
E13 Other specified diabetes mellitus
0.750 0.250 0.000
H43.9 Disorder of vitreous body, unspecified
0.750 0.250 0.000
M23.1 Discoid meniscus (congenital)
0.748 0.252 0.000
M32 Systemic lupus erythematosus
0.747 0.252 0.000
S43.1 Dislocation of acromioclavicular joint
0.747 0.253 0.000
E16.1 Other hypoglycaemia
0.746 0.254 0.000
L23 Allergic contact dermatitis
0.745 0.255 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.745 0.255 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.745 0.255 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.744 0.256 0.000
W50-W64 Exposure to animate mechanical forces
0.743 0.257 0.000
D80 Immunodeficiency with predominantly antibody defects
0.742 0.258 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.742 0.258 0.000
E73 Lactose intolerance
0.742 0.258 0.000
K35-K38 Diseases of appendix
0.741 0.259 0.001
H43.2 Crystalline deposits in vitreous body
0.736 0.264 0.000
W75-W84 Other accidental threats to breathing
0.736 0.264 0.000
E78.6 Lipoprotein deficiency
0.735 0.265 0.000
E83 Disorders of mineral metabolism
0.664 0.265 0.071
H35.4 Peripheral retinal degeneration
0.734 0.266 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.733 0.267 0.000
H53-H54 Visual disturbances and blindness
0.733 0.267 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.732 0.268 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.731 0.269 0.000
M35.3 Polymyalgia rheumatica
0.730 0.270 0.000
M33 Dermatopolymyositis
0.728 0.272 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.728 0.272 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.728 0.272 0.000
H35.2 Other proliferative retinopathy
0.728 0.272 0.000
D86.3 Sarcoidosis of skin
0.728 0.272 0.000
M10.94 Gout, unspecified (Hand)
0.727 0.273 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.726 0.274 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.726 0.274 0.000
W06 Fall involving bed
0.725 0.275 0.000
M21 Other acquired deformities of limbs
0.725 0.275 0.000
M22.0 Recurrent dislocation of patella
0.724 0.276 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.724 0.276 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.722 0.278 0.000
E78.1 Pure hyperglyceridaemia
0.722 0.278 0.000
H05.0 Acute inflammation of orbit
0.721 0.279 0.000
S06 Intracranial injury
0.721 0.279 0.000
H35.7 Separation of retinal layers
0.721 0.279 0.000
S84 Injury of nerves at lower leg level
0.720 0.280 0.000
V01-V09 Pedestrian injured in transport accident
0.720 0.280 0.000
M14.6 Neuropathic arthropathy
0.719 0.281 0.000
M17.5 Other secondary gonarthrosis
0.718 0.282 0.000
H47.2 Optic atrophy
0.718 0.282 0.000
D62 Acute posthaemorrhagic anaemia
0.718 0.282 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
M62.6 Muscle strain
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.717 0.283 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.717 0.283 0.000
T16 Foreign body in ear
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
L30.8 Other specified dermatitis
0.717 0.283 0.000
Q39 Congenital malformations of oesophagus
0.716 0.284 0.000
K90.3 Pancreatic steatorrhoea
0.716 0.284 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.716 0.284 0.000
K90.1 Tropical sprue
0.716 0.284 0.000
N99-N99 Other disorders of the genitourinary system
0.000 0.284 0.716
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.714 0.285 0.002
E11.6 With other specified complications
0.714 0.286 0.000
K77 Liver disorders in diseases classified elsewhere
0.714 0.286 0.000
K71 Toxic liver disease
0.714 0.286 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
M06.8 Other specified rheumatoid arthritis
0.714 0.286 0.000
M06.2 Rheumatoid bursitis
0.714 0.286 0.000
M06.1 Adult-onset Still's disease
0.714 0.286 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.286 0.713
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.286 0.713
K75.3 Granulomatous hepatitis, not elsewhere classified
0.713 0.286 0.000
K75.2 Nonspecific reactive hepatitis
0.713 0.286 0.000
K75.1 Phlebitis of portal vein
0.713 0.286 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.287 0.713
W19.9 Unspecified place
0.713 0.287 0.000
C85.1 B-cell lymphoma, unspecified
0.713 0.287 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.712 0.288 0.000
E14.2 Withrenal complications
0.711 0.289 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.711 0.289 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.710 0.290 0.000
E32 Diseases of thymus
0.710 0.290 0.000
E31 Polyglandular dysfunction
0.710 0.290 0.000
E30 Disorders of puberty, not elsewhere classified
0.710 0.290 0.000
E25 Adrenogenital disorders
0.710 0.290 0.000
E27.5 Adrenomedullary hyperfunction
0.710 0.290 0.000
E27.0 Other adrenocortical overactivity
0.710 0.290 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.709 0.291 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.709 0.291 0.000
M35.8 Other specified systemic involvement of connective tissue
0.709 0.291 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.709 0.291 0.000
M35.5 Multifocal fibrosclerosis
0.709 0.291 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.709 0.291 0.000
M31.9 Necrotising vasculopathy, unspecified
0.709 0.291 0.000
M31.8 Other specified necrotising vasculopathies
0.709 0.291 0.000
M31.7 Microscopic polyangiitis
0.709 0.291 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.709 0.291 0.000
M31.2 Lethal midline granuloma
0.709 0.291 0.000
M31.1 Thrombotic microangiopathy
0.709 0.291 0.000
M31.0 Hypersensitivity angiitis
0.709 0.291 0.000
N32.3 Diverticulum of bladder
0.000 0.291 0.709
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.291 0.708
W09 Fall involving playground equipment
0.708 0.292 0.000
S48 Traumatic amputation of shoulder and upper arm
0.707 0.293 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.707 0.293 0.000
S44 Injury of nerves at shoulder and upper arm level
0.707 0.293 0.000
S47 Crushing injury of shoulder and upper arm
0.707 0.293 0.000
K73.9 Chronic hepatitis, unspecified
0.707 0.293 0.000
S20 Superficial injury of thorax
0.705 0.295 0.000
E23.2 Diabetes insipidus
0.705 0.295 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.705 0.295 0.000
Q00-Q07 Congenital malformations of the nervous system
0.704 0.295 0.000
W19.3 Sports and athletics area
0.704 0.296 0.000
H34.0 Transient retinal artery occlusion
0.704 0.296 0.000
C04 Malignant neoplasm of floor of mouth
0.704 0.296 0.000
D82 Immunodeficiency associated with other major defects
0.704 0.296 0.000
D81 Combined immunodeficiencies
0.704 0.296 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.703 0.297 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.703 0.297 0.000
H35.1 Retinopathy of prematurity
0.702 0.298 0.000
E05.8 Other thyrotoxicosis
0.702 0.298 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.702 0.298 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.299 0.701
M35.2 Behcet's disease
0.701 0.299 0.000
M10.90 Gout, unspecified (Multiple sites)
0.701 0.299 0.000
T79.8 Other early complications of trauma
0.701 0.299 0.000
K46 Unspecified abdominal hernia
0.001 0.300 0.700
S08 Traumatic amputation of part of head
0.699 0.301 0.000
S07 Crushing injury of head
0.699 0.301 0.000
S04 Injury of cranial nerves
0.699 0.301 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.699 0.301 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.698 0.302 0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level
0.697 0.302 0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level
0.697 0.302 0.000
W19.2 School, other institution and public administrative area
0.697 0.303 0.000
M24.2 Disorder of ligament
0.696 0.304 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.305 0.695
N44 Torsion of testis
0.000 0.305 0.695
M62.86 Other specified disorders of muscle (Lower leg)
0.695 0.305 0.000
W13 Fall from, out of or through building or structure
0.694 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
E84 Cystic fibrosis
0.693 0.306 0.000
H26.3 Drug-induced cataract
0.693 0.307 0.000
M76 Enthesopathies of lower limb, excluding foot
0.693 0.307 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.692 0.308 0.000
X60-X84 Intentional self-harm
0.691 0.309 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.691 0.309 0.000
M34.0 Progressive systemic sclerosis
0.691 0.309 0.000
S98 Traumatic amputation of ankle and foot
0.690 0.309 0.000
S97 Crushing injury of ankle and foot
0.690 0.309 0.000
S95 Injury of blood vessels at ankle and foot level
0.690 0.309 0.000
S94 Injury of nerves at ankle and foot level
0.690 0.309 0.000
N42.3 Dysplasia of prostate
0.000 0.310 0.690
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
N42.2 Atrophy of prostate
0.000 0.310 0.689
M13.0 Polyarthritis, unspecified
0.688 0.312 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.688 0.312 0.000
D59 Acquired haemolytic anaemia
0.687 0.312 0.000
D53 Other nutritional anaemias
0.687 0.313 0.000
K35 Acute appendicitis
0.687 0.313 0.000
M24.5 Contracture of joint
0.687 0.313 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.686 0.314 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.685 0.315 0.000
K90.8 Other intestinal malabsorption
0.685 0.315 0.000
M22.1 Recurrent subluxation of patella
0.684 0.315 0.000
M22.9 Disorder of patella, unspecified
0.684 0.315 0.000
M06.3 Rheumatoid nodule
0.684 0.316 0.000
H35.3 Degeneration of macula and posterior pole
0.684 0.316 0.000
H35.0 Background retinopathy and retinal vascular changes
0.683 0.317 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.683 0.317 0.000
H33 Retinal detachments and breaks
0.682 0.318 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.682 0.318 0.000
Q43 Other congenital malformations of intestine
0.682 0.318 0.000
T02 Fractures involving multiple body regions
0.681 0.319 0.000
N37 Urethral disorders in diseases classified elsewhere
0.000 0.319 0.681
N33 Bladder disorders in diseases classified elsewhere
0.000 0.319 0.681
S02.8 Fractures of other skull and facial bones
0.681 0.319 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.680 0.320 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.680 0.320 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.680 0.320 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.680 0.320 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.320 0.680
N32.2 Vesical fistula, not elsewhere classified
0.000 0.320 0.680
T20 Burn and corrosion of head and neck
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
N42.0 Calculus of prostate
0.000 0.320 0.680
Q45 Other congenital malformations of digestive system
0.679 0.321 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.679 0.321 0.000
Q51 Congenital malformations of uterus and cervix
0.679 0.321 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.678 0.322 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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