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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3734574
log Bayes Factor = 15.3464
Chromosome 6   position 27,371,193  (GRCh37) Explore rs3734574 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.479 0.521
E10.9 Without complications
0.000 0.485 0.515
E10.4 With neurological complications
0.000 0.512 0.488
E10.5 With peripheral circulatory complications
0.000 0.521 0.479
E10.6 With other specified complications
0.000 0.531 0.469
E10.8 With unspecified complications
0.000 0.561 0.439
E10-E14 Diabetes mellitus
0.000 0.595 0.405
E10.1 With ketoacidosis
0.000 0.610 0.390
E10.2 With renal complications
0.000 0.611 0.388
E10.7 With multiple complications
0.000 0.627 0.373
E10.3 With ophthalmic complications
0.000 0.633 0.367
E10.0 With coma
0.000 0.647 0.352
E13 Other specified diabetes mellitus
0.000 0.660 0.339
E83 Disorders of mineral metabolism
0.000 0.666 0.334
E14 Unspecified diabetes mellitus
0.000 0.679 0.321
E14.3 With ophthalmic complications
0.000 0.693 0.307
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.704 0.296
E13.9 Without complications
0.000 0.705 0.295
E70-E90 Metabolic disorders
0.000 0.708 0.292
E12 Malnutrition-related diabetes mellitus
0.000 0.709 0.290
K90 Intestinal malabsorption
0.000 0.712 0.288
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.745 0.255
E40-E46 Malnutrition
0.000 0.752 0.248
E88 Other metabolic disorders
0.000 0.754 0.246
E13.8 With unspecified complications
0.000 0.756 0.243
E13.7 With multiple complications
0.000 0.756 0.243
E13.6 With other specified complications
0.000 0.756 0.243
E13.5 With peripheral circulatory complications
0.000 0.756 0.243
E13.4 With neurological complications
0.000 0.756 0.243
E13.2 With renal complications
0.000 0.756 0.243
E13.1 With ketoacidosis
0.000 0.756 0.243
E13.0 With coma
0.000 0.756 0.243
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.760 0.240
E83.8 Other disorders of mineral metabolism
0.000 0.760 0.240
E83.2 Disorders of zinc metabolism
0.000 0.760 0.240
E83.0 Disorders of copper metabolism
0.000 0.760 0.240
E14.5 With peripheral circulatory complications
0.000 0.761 0.239
E13.3 With ophthalmic complications
0.000 0.762 0.238
E85 Amyloidosis
0.000 0.764 0.236
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.770 0.230
E14.7 With multiple complications
0.000 0.770 0.230
E14.6 With other specified complications
0.000 0.770 0.230
E14.2 Withrenal complications
0.000 0.770 0.230
E14.0 With coma
0.000 0.770 0.230
E16 Other disorders of pancreatic internal secretion
0.000 0.775 0.225
E14.4 With neurological complications
0.000 0.778 0.222
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.783 0.217
E46 Unspecified protein-energy malnutrition
0.000 0.786 0.214
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.786 0.214
E16.2 Hypoglycaemia, unspecified
0.000 0.789 0.211
E14.1 With ketoacidosis
0.000 0.789 0.210
E84 Cystic fibrosis
0.000 0.790 0.209
E77 Disorders of glycoprotein metabolism
0.000 0.790 0.209
E76 Disorders of glycosaminoglycan metabolism
0.000 0.790 0.209
E72 Other disorders of amino-acid metabolism
0.000 0.790 0.209
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.790 0.209
E70 Disorders of aromatic amino-acid metabolism
0.000 0.790 0.209
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.790 0.209
E12.9 Without complications
0.000 0.791 0.208
E12.8 With unspecified complications
0.000 0.791 0.208
E12.7 With multiple complications
0.000 0.791 0.208
E12.6 With other specified complications
0.000 0.791 0.208
E12.5 With peripheral circulatory complications
0.000 0.791 0.208
E12.4 With neurological complications
0.000 0.791 0.208
E12.3 With ophthalmic complications
0.000 0.791 0.208
E12.2 With renal complications
0.000 0.791 0.208
E12.1 With ketoacidosis
0.000 0.791 0.208
E12.0 With coma
0.000 0.791 0.208
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.793 0.207
K90.3 Pancreatic steatorrhoea
0.000 0.793 0.206
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.793 0.206
K90.1 Tropical sprue
0.000 0.793 0.206
E65-E68 Obesity and other hyperalimentation
0.000 0.798 0.202
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.799 0.201
K90.8 Other intestinal malabsorption
0.000 0.801 0.198
E11 Non-insulin-dependent diabetes mellitus
0.000 0.802 0.198
E85.9 Amyloidosis, unspecified
0.000 0.803 0.197
E14.8 With unspecified complications
0.000 0.810 0.190
E79 Disorders of purine and pyrimidine metabolism
0.000 0.810 0.190
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.812 0.188
E88.8 Other specified metabolic disorders
0.000 0.813 0.187
E88.2 Lipomatosis, not elsewhere classified
0.000 0.814 0.185
E15 Nondiabetic hypoglycaemic coma
0.000 0.817 0.183
E85.4 Organ-limited amyloidosis
0.000 0.822 0.178
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.822 0.178
E45 Retarded development following protein-energy malnutrition
0.000 0.822 0.178
E43 Unspecified severe protein-energy malnutrition
0.000 0.822 0.178
E42 Marasmic kwashiorkor
0.000 0.822 0.178
E41 Nutritional marasmus
0.000 0.822 0.178
E40 Kwashiorkor
0.000 0.822 0.178
E88.3 Tumour lysis syndrome
0.000 0.822 0.177
E89.2 Postprocedural hypoparathyroidism
0.000 0.826 0.174
E74 Other disorders of carbohydrate metabolism
0.000 0.827 0.173
E65 Localised adiposity
0.000 0.828 0.172
E85.8 Other amyloidosis
0.000 0.830 0.170
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.830 0.170
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.830 0.170
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.830 0.170
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.832 0.168
E11.5 With peripheral circulatory complications
0.000 0.833 0.167
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.833 0.167
E88.9 Metabolic disorder, unspecified
0.000 0.836 0.164
E89.0 Postprocedural hypothyroidism
0.000 0.838 0.162
E89.4 Postprocedural ovarian failure
0.000 0.838 0.162
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.839 0.161
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.839 0.161
E16.4 Abnormal secretion of gastrin
0.000 0.839 0.161
E16.3 Increased secretion of glucagon
0.000 0.839 0.161
E80.4 Gilbert's syndrome
0.000 0.842 0.158
E85.3 Secondary systemic amyloidosis
0.000 0.842 0.158
E75.5 Other lipid storage disorders
0.000 0.842 0.158
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.844 0.155
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.844 0.155
E89.5 Postprocedural testicular hypofunction
0.000 0.844 0.155
E89.1 Postprocedural hypoinsulinaemia
0.000 0.844 0.155
E75.6 Lipid storage disorder, unspecified
0.000 0.846 0.153
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.846 0.153
E75.3 Sphingolipidosis, unspecified
0.000 0.846 0.153
E75.2 Other sphingolipidosis
0.000 0.846 0.153
E75.1 Other gangliosidosis
0.000 0.846 0.153
E75.0 GM2 gangliosidosis
0.000 0.846 0.153
E11.0 With coma
0.000 0.848 0.152
E73 Lactose intolerance
0.001 0.848 0.151
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.849 0.150
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.849 0.150
E70.3 Albinism
0.000 0.849 0.150
E70.2 Disorders of tyrosine metabolism
0.000 0.849 0.150
E70.1 Other hyperphenylalaninaemias
0.000 0.849 0.150
E70.0 Classical phenylketonuria
0.000 0.849 0.150
E71.3 Disorders of fatty-acid metabolism
0.000 0.849 0.150
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.849 0.150
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.849 0.150
E71.0 Maple-syrup-urine disease
0.000 0.849 0.150
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.849 0.150
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.849 0.150
E72.5 Disorders of glycine metabolism
0.000 0.849 0.150
E72.4 Disorders of ornithine metabolism
0.000 0.849 0.150
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.849 0.150
E72.2 Disorders of urea cycle metabolism
0.000 0.849 0.150
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.849 0.150
E72.0 Disorders of amino-acid transport
0.000 0.849 0.150
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.849 0.150
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.849 0.150
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.849 0.150
E76.2 Other mucopolysaccharidoses
0.000 0.849 0.150
E76.1 Mucopolysaccharidosis, type II
0.000 0.849 0.150
E76.0 Mucopolysaccharidosis, type I
0.000 0.849 0.150
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.849 0.150
E77.8 Other disorders of glycoprotein metabolism
0.000 0.849 0.150
E77.1 Defects in glycoprotein degradation
0.000 0.849 0.150
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.849 0.150
E84.9 Cystic fibrosis, unspecified
0.000 0.849 0.150
E84.8 Cystic fibrosis with other manifestations
0.000 0.849 0.150
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.849 0.150
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.849 0.150
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.851 0.149
E80.5 Crigler-Najjar syndrome
0.000 0.851 0.149
E80.3 Defects of catalase and peroxydase
0.000 0.851 0.149
E80.1 Porphyria cutanea tarda
0.000 0.851 0.149
E80.0 Hereditary erythropoietic porphyria
0.000 0.851 0.149
E11.8 With unspecified complications
0.000 0.852 0.148
E11.1 With ketoacidosis
0.000 0.854 0.146
E67 Other hyperalimentation
0.000 0.855 0.145
E68 Sequelae of hyperalimentation
0.000 0.855 0.145
E83.3 Disorders of phosphorus metabolism
0.000 0.856 0.144
E80.2 Other porphyria
0.000 0.857 0.143
E11.7 With multiple complications
0.000 0.858 0.142
E80.6 Other disorders of bilirubin metabolism
0.000 0.858 0.142
E00-E07 Disorders of thyroid gland
0.000 0.860 0.140
E11.2 With renal complications
0.000 0.861 0.138
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.864 0.136
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.864 0.136
E79.1 Lesch-Nyhan syndrome
0.000 0.864 0.136
E11.6 With other specified complications
0.000 0.864 0.136
E11.4 With neurological complications
0.000 0.864 0.136
E83.4 Disorders of magnesium metabolism
0.000 0.870 0.130
E44.1 Mild protein-energy malnutrition
0.000 0.872 0.128
E44.0 Moderate protein-energy malnutrition
0.000 0.872 0.128
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.875 0.124
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.875 0.124
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.875 0.124
E74.2 Disorders of galactose metabolism
0.000 0.875 0.124
E74.1 Disorders of fructose metabolism
0.000 0.875 0.124
E16.1 Other hypoglycaemia
0.000 0.878 0.122
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.880 0.120
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.883 0.116
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.884 0.116
E74.0 Glycogen storage disease
0.000 0.886 0.114
E11.3 With ophthalmic complications
0.000 0.887 0.113
E04 Other non-toxic goitre
0.000 0.888 0.112
E73.8 Other lactose intolerance
0.001 0.891 0.108
E73.1 Secondary lactase deficiency
0.001 0.891 0.108
E73.0 Congenital lactase deficiency
0.001 0.891 0.108
E07 Other disorders of thyroid
0.000 0.894 0.106
E67.8 Other specified hyperalimentation
0.000 0.896 0.104
E67.3 Hypervitaminosis D
0.000 0.896 0.104
E67.2 Megavitamin-B6 syndrome
0.000 0.896 0.104
E67.1 Hypercarotenaemia
0.000 0.896 0.104
E67.0 Hypervitaminosis A
0.000 0.896 0.104
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.897 0.103
E04.9 Non-toxic goitre, unspecified
0.000 0.899 0.101
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.899 0.101
E00 Congenital iodine-deficiency syndrome
0.000 0.899 0.101
E50-E64 Other nutritional deficiencies
0.000 0.901 0.098
E14.9 Without complications
0.000 0.903 0.097
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.904 0.096
E06 Thyroiditis
0.000 0.904 0.095
E78.4 Other hyperlipidaemia
0.000 0.906 0.094
E89.3 Postprocedural hypopituitarism
0.000 0.906 0.094
E03 Other hypothyroidism
0.000 0.908 0.092
E78.6 Lipoprotein deficiency
0.000 0.909 0.091
K90.9 Intestinal malabsorption, unspecified
0.001 0.911 0.089
E83.5 Disorders of calcium metabolism
0.000 0.912 0.088
E87.3 Alkalosis
0.000 0.913 0.087
E07.9 Disorder of thyroid, unspecified
0.000 0.914 0.086
E78.3 Hyperchylomicronaemia
0.000 0.914 0.086
E04.0 Non-toxic diffuse goitre
0.000 0.915 0.085
E20-E35 Disorders of other endocrine glands
0.000 0.917 0.083
E03.8 Other specified hypothyroidism
0.000 0.917 0.083
E78.1 Pure hyperglyceridaemia
0.000 0.919 0.081
E04.8 Other specified non-toxic goitre
0.000 0.919 0.081
E87.0 Hyperosmolality and hypernatraemia
0.000 0.920 0.080
E78.2 Mixed hyperlipidaemia
0.000 0.921 0.079
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.923 0.077
E07.1 Dyshormogenetic goitre
0.000 0.924 0.076
E07.0 Hypersecretion of calcitonin
0.000 0.924 0.076
E04.2 Non-toxic multinodular goitre
0.000 0.926 0.074
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.927 0.072
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.927 0.072
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.927 0.072
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.927 0.072
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.927 0.072
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.927 0.072
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.927 0.072
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.927 0.072
E87.7 Fluid overload
0.000 0.928 0.072
E66 Obesity
0.000 0.929 0.071
E06.3 Autoimmune thyroiditis
0.000 0.929 0.071
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.929 0.071
E63 Other nutritional deficiencies
0.000 0.929 0.071
E56 Other vitamin deficiencies
0.000 0.929 0.071
E50 Vitamin A deficiency
0.000 0.929 0.071
E60 Dietary zinc deficiency
0.000 0.929 0.071
E59 Dietary selenium deficiency
0.000 0.929 0.071
E54 Ascorbic acid deficiency
0.000 0.929 0.071
E52 Niacin deficiency [pellagra]
0.000 0.929 0.071
E58 Dietary calcium deficiency
0.000 0.930 0.070
E87.4 Mixed disorder of acid-base balance
0.000 0.931 0.069
E06.5 Other chronic thyroiditis
0.000 0.931 0.069
E06.4 Drug-induced thyroiditis
0.000 0.931 0.069
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.931 0.069
E06.1 Subacute thyroiditis
0.000 0.931 0.069
E06.0 Acute thyroiditis
0.000 0.931 0.069
E07.8 Other specified disorders of thyroid
0.000 0.933 0.067
E87.2 Acidosis
0.000 0.934 0.066
E03.5 Myxoedema coma
0.000 0.934 0.066
E03.4 Atrophy of thyroid (acquired)
0.000 0.934 0.066
E03.3 Postinfectious hypothyroidism
0.000 0.934 0.066
E03.1 Congenital hypothyroidism without goitre
0.000 0.934 0.066
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.934 0.066
E51 Thiamine deficiency
0.000 0.934 0.065
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.935 0.065
E53 Deficiency of other B group vitamins
0.000 0.936 0.064
E20 Hypoparathyroidism
0.000 0.937 0.063
E26 Hyperaldosteronism
0.000 0.938 0.062
E28 Ovarian dysfunction
0.000 0.938 0.062
E06.9 Thyroiditis, unspecified
0.000 0.940 0.060
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.940 0.060
E29 Testicular dysfunction
0.000 0.940 0.060
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.940 0.060
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.940 0.060
E32 Diseases of thymus
0.000 0.940 0.060
E31 Polyglandular dysfunction
0.000 0.940 0.060
E30 Disorders of puberty, not elsewhere classified
0.000 0.940 0.060
E25 Adrenogenital disorders
0.000 0.940 0.060
E23 Hypofunction and other disorders of pituitary gland
0.000 0.941 0.059
E04.1 Non-toxic single thyroid nodule
0.000 0.942 0.058
E87.5 Hyperkalaemia
0.000 0.943 0.057
E55 Vitamin D deficiency
0.000 0.944 0.056
E34 Other endocrine disorders
0.000 0.946 0.054
E28.2 Polycystic ovarian syndrome
0.000 0.946 0.054
E23.2 Diabetes insipidus
0.000 0.946 0.054
E24 Cushing's syndrome
0.000 0.946 0.054
E66.1 Drug-induced obesity
0.000 0.949 0.051
E78.8 Other disorders of lipoprotein metabolism
0.000 0.949 0.051
E50.9 Vitamin A deficiency, unspecified
0.000 0.949 0.051
E50.8 Other manifestations of vitamin A deficiency
0.000 0.949 0.051
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.949 0.051
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.949 0.051
E50.5 Vitamin A deficiency with night blindness
0.000 0.949 0.051
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.949 0.051
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.949 0.051
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.949 0.051
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.949 0.051
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.949 0.051
E56.9 Vitamin deficiency, unspecified
0.000 0.949 0.051
E56.8 Deficiency of other vitamins
0.000 0.949 0.051
E56.1 Deficiency of vitamin K
0.000 0.949 0.051
E56.0 Deficiency of vitamin E
0.000 0.949 0.051
E63.9 Nutritional deficiency, unspecified
0.000 0.949 0.051
E63.8 Other specified nutritional deficiencies
0.000 0.949 0.051
E63.1 Imbalance of constituents of food intake
0.000 0.949 0.051
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.949 0.051
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.949 0.051
E64.8 Sequelae of other nutritional deficiencies
0.000 0.949 0.051
E64.3 Sequelae of rickets
0.000 0.949 0.051
E64.2 Sequelae of vitamin C deficiency
0.000 0.949 0.051
E64.1 Sequelae of vitamin A deficiency
0.000 0.949 0.051
E64.0 Sequelae of protein-energy malnutrition
0.000 0.949 0.051
E73.9 Lactose intolerance, unspecified
0.001 0.949 0.050
E27 Other disorders of adrenal gland
0.000 0.950 0.050
E66.0 Obesity due to excess calories
0.000 0.951 0.049
E20.9 Hypoparathyroidism, unspecified
0.000 0.951 0.049
E26.0 Primary hyperaldosteronism
0.000 0.952 0.047
E51.9 Thiamine deficiency, unspecified
0.000 0.953 0.047
E51.8 Other manifestations of thiamine deficiency
0.000 0.953 0.047
E51.1 Beriberi
0.000 0.953 0.047
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.953 0.047
E27.1 Primary adrenocortical insufficiency
0.000 0.953 0.047
E53.1 Pyridoxine deficiency
0.000 0.954 0.046
E53.0 Riboflavin deficiency
0.000 0.954 0.046
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.954 0.046
E53.9 Vitamin B deficiency, unspecified
0.000 0.954 0.046
E20.8 Other hypoparathyroidism
0.000 0.954 0.045
E20.1 Pseudohypoparathyroidism
0.000 0.954 0.045
E20.0 Idiopathic hypoparathyroidism
0.000 0.954 0.045
E26.9 Hyperaldosteronism, unspecified
0.000 0.955 0.045
E26.8 Other hyperaldosteronism
0.000 0.955 0.045
E26.1 Secondary hyperaldosteronism
0.000 0.955 0.045
E05.8 Other thyrotoxicosis
0.000 0.955 0.045
E24.2 Drug-induced Cushing's syndrome
0.000 0.955 0.045
E28.9 Ovarian dysfunction, unspecified
0.000 0.955 0.044
E28.8 Other ovarian dysfunction
0.000 0.955 0.044
E28.1 Androgen excess
0.000 0.955 0.044
E28.0 Oestrogen excess
0.000 0.955 0.044
E05.5 Thyroid crisis or storm
0.000 0.957 0.043
E05.4 Thyrotoxicosis factitia
0.000 0.957 0.043
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.957 0.043
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.957 0.043
E29.1 Testicular hypofunction
0.000 0.957 0.043
E29.9 Testicular dysfunction, unspecified
0.000 0.957 0.043
E29.8 Other testicular dysfunction
0.000 0.957 0.043
E29.0 Testicular hyperfunction
0.000 0.957 0.043
E25.9 Adrenogenital disorder, unspecified
0.000 0.957 0.043
E25.8 Other adrenogenital disorders
0.000 0.957 0.043
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.957 0.043
E30.9 Disorder of puberty, unspecified
0.000 0.957 0.043
E30.8 Other disorders of puberty
0.000 0.957 0.043
E30.1 Precocious puberty
0.000 0.957 0.043
E30.0 Delayed puberty
0.000 0.957 0.043
E31.9 Polyglandular dysfunction, unspecified
0.000 0.957 0.043
E31.8 Other polyglandular dysfunction
0.000 0.957 0.043
E31.1 Polyglandular hyperfunction
0.000 0.957 0.043
E31.0 Autoimmune polyglandular failure
0.000 0.957 0.043
E32.9 Disease of thymus, unspecified
0.000 0.957 0.043
E32.8 Other diseases of thymus
0.000 0.957 0.043
E32.1 Abscess of thymus
0.000 0.957 0.043
E32.0 Persistent hyperplasia of thymus
0.000 0.957 0.043
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.957 0.043
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.957 0.043
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.957 0.043
E23.7 Disorder of pituitary gland, unspecified
0.000 0.957 0.043
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.957 0.043
E23.1 Drug-induced hypopituitarism
0.000 0.957 0.043
E51.2 Wernicke's encephalopathy
0.000 0.958 0.041
E55.0 Rickets, active
0.000 0.959 0.040
E53.8 Deficiency of other specified B group vitamins
0.000 0.960 0.040
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.961 0.039
E34.5 Androgen resistance syndrome
0.000 0.961 0.039
E34.4 Constitutional tall stature
0.000 0.961 0.039
E34.3 Short stature, not elsewhere classified
0.000 0.961 0.039
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.961 0.039
E34.1 Other hypersecretion of intestinal hormones
0.000 0.961 0.039
E34.9 Endocrine disorder, unspecified
0.000 0.961 0.039
E24.8 Other Cushing's syndrome
0.000 0.961 0.039
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.961 0.039
E24.3 Ectopic ACTH syndrome
0.000 0.961 0.039
E24.1 Nelson's syndrome
0.000 0.961 0.039
E34.8 Other specified endocrine disorders
0.000 0.962 0.038
E61 Deficiency of other nutrient elements
0.001 0.962 0.037
E23.6 Other disorders of pituitary gland
0.000 0.963 0.037
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.963 0.037
E27.5 Adrenomedullary hyperfunction
0.000 0.964 0.036
E27.0 Other adrenocortical overactivity
0.000 0.964 0.036
E34.0 Carcinoid syndrome
0.000 0.964 0.035
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.965 0.035
E24.0 Pituitary-dependent Cushing's disease
0.000 0.965 0.034
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.970 0.030
E21.3 Hyperparathyroidism, unspecified
0.000 0.971 0.029
E28.3 Primary ovarian failure
0.000 0.971 0.028
E21.4 Other specified disorders of parathyroid gland
0.000 0.971 0.028
E21.2 Other hyperparathyroidism
0.000 0.971 0.028
E27.2 Addisonian crisis
0.000 0.972 0.028
E22 Hyperfunction of pituitary gland
0.000 0.972 0.028
E86 Volume depletion
0.000 0.972 0.028
R31 Unspecified haematuria
0.027 0.973 0.000
E61.9 Deficiency of nutrient element, unspecified
0.001 0.973 0.027
E61.8 Deficiency of other specified nutrient elements
0.001 0.973 0.027
E61.7 Deficiency of multiple nutrient elements
0.001 0.973 0.027
E61.6 Vanadium deficiency
0.001 0.973 0.027
E61.5 Molybdenum deficiency
0.001 0.973 0.027
E61.4 Chromium deficiency
0.001 0.973 0.027
E61.3 Manganese deficiency
0.001 0.973 0.027
E61.0 Copper deficiency
0.001 0.973 0.027
E24.9 Cushing's syndrome, unspecified
0.000 0.973 0.026
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.974 0.026
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.974 0.026
E55.9 Vitamin D deficiency, unspecified
0.000 0.974 0.026
E27.8 Other specified disorders of adrenal gland
0.000 0.976 0.023
E66.9 Obesity, unspecified
0.000 0.976 0.024
E23.0 Hypopituitarism
0.000 0.978 0.022
E61.2 Magnesium deficiency
0.001 0.979 0.021
E27.9 Disorder of adrenal gland, unspecified
0.000 0.979 0.021
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.980 0.020
E22.8 Other hyperfunction of pituitary gland
0.000 0.980 0.020
K90-K93 Other diseases of the digestive system
0.000 0.982 0.018
E22.1 Hyperprolactinaemia
0.000 0.982 0.018
E21.0 Primary hyperparathyroidism
0.000 0.983 0.017
E22.0 Acromegaly and pituitary gigantism
0.000 0.986 0.014
C71.2 Temporal lobe
0.014 0.986 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.986 0.014
C71 Malignant neoplasm of brain
0.014 0.986 0.000
C71.9 Brain, unspecified
0.013 0.987 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.987 0.013
E87.6 Hypokalaemia
0.000 0.988 0.012
C71.3 Parietal lobe
0.011 0.988 0.000
C71.1 Frontal lobe
0.011 0.989 0.000
C71.7 Brain stem
0.010 0.989 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.990 0.010
M41.9 Scoliosis, unspecified
0.010 0.990 0.000
C71.6 Cerebellum
0.010 0.990 0.000
C71.5 Cerebral ventricle
0.010 0.990 0.000
C71.0 Cerebrum, except lobes and ventricles
0.010 0.990 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.010 0.990 0.000
C71.8 Overlapping lesion of brain
0.010 0.990 0.000
E61.1 Iron deficiency
0.001 0.990 0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.990 0.010
K93.1 Megacolon in Chagas' disease
0.000 0.990 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.990 0.010
E66.8 Other obesity
0.000 0.990 0.010
G44.2 Tension-type headache
0.010 0.990 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.010 0.990 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.009 0.990 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.009 0.991 0.000
G31.8 Other specified degenerative diseases of nervous system
0.000 0.991 0.009
C71.4 Occipital lobe
0.008 0.991 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.008 0.992 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.992 0.008
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.008 0.992 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.008 0.992 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.008 0.992 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.008 0.992 0.000
G31.0 Circumscribed brain atrophy
0.000 0.993 0.007
C69 Malignant neoplasm of eye and adnexa
0.007 0.993 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.993 0.007
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.007 0.993 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.006 0.993 0.000
C70 Malignant neoplasm of meninges
0.006 0.994 0.000
C69.9 Eye, unspecified
0.006 0.994 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.994 0.006
M79.10 Myalgia (Multiple sites)
0.006 0.994 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.006 0.994 0.000
N04.9 Unspecified
0.000 0.994 0.006
K22.8 Other specified diseases of oesophagus
0.006 0.994 0.000
C69.3 Choroid
0.006 0.994 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.006 0.994 0.000
C69.8 Overlapping lesion of eye and adnexa
0.005 0.995 0.000
C69.5 Lachrymal gland and duct
0.005 0.995 0.000
C69.4 Ciliary body
0.005 0.995 0.000
C69.2 Retina
0.005 0.995 0.000
C69.1 Cornea
0.005 0.995 0.000
C70.0 Cerebral meninges
0.005 0.995 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.005 0.995 0.000
C69.6 Orbit
0.005 0.995 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.995 0.005
C69.0 Conjunctiva
0.005 0.995 0.000
M41 Scoliosis
0.005 0.995 0.000
C70.9 Meninges, unspecified
0.005 0.995 0.000
C70.1 Spinal meninges
0.005 0.995 0.000
G44 Other headache syndromes
0.005 0.995 0.000
K62.5 Haemorrhage of anus and rectum
0.005 0.995 0.000
G30-G32 Other degenerative diseases of the nervous system
0.000 0.995 0.005
M67.8 Other specified disorders of synovium and tendon
0.000 0.995 0.005
C72.9 Central nervous system, unspecified
0.004 0.996 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.004 0.996 0.000
C72.5 Other and unspecified cranial nerves
0.004 0.996 0.000
C72.4 Acoustic nerve
0.004 0.996 0.000
C72.3 Optic nerve
0.004 0.996 0.000
C72.2 Olfactory nerve
0.004 0.996 0.000
C72.1 Cauda equina
0.004 0.996 0.000
G44.8 Other specified headache syndromes
0.004 0.996 0.000
G30 Alzheimer's disease
0.000 0.996 0.004
C72.0 Spinal cord
0.004 0.996 0.000
M79.19 Myalgia (Site unspecified)
0.004 0.996 0.000
G30.0 Alzheimer's disease with early onset
0.000 0.996 0.004
M41.5 Other secondary scoliosis
0.004 0.996 0.000
M41.4 Neuromuscular scoliosis
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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