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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3734575
log Bayes Factor = 15.1671
Chromosome 6   position 27,371,011  (GRCh37) Explore rs3734575 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.537 0.463
E10.9 Without complications
0.000 0.541 0.459
E10.4 With neurological complications
0.000 0.563 0.437
E10.5 With peripheral circulatory complications
0.000 0.574 0.426
E10.6 With other specified complications
0.000 0.583 0.417
E10.8 With unspecified complications
0.000 0.610 0.390
E10-E14 Diabetes mellitus
0.000 0.652 0.348
E10.1 With ketoacidosis
0.000 0.653 0.347
E10.2 With renal complications
0.000 0.660 0.340
E10.7 With multiple complications
0.000 0.668 0.332
E10.0 With coma
0.000 0.686 0.314
E83 Disorders of mineral metabolism
0.000 0.704 0.296
E13 Other specified diabetes mellitus
0.000 0.705 0.295
E10.3 With ophthalmic complications
0.000 0.706 0.294
K90 Intestinal malabsorption
0.000 0.711 0.289
E14 Unspecified diabetes mellitus
0.000 0.734 0.266
E13.9 Without complications
0.000 0.741 0.259
E14.3 With ophthalmic complications
0.000 0.746 0.254
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.749 0.251
E12 Malnutrition-related diabetes mellitus
0.000 0.750 0.250
E70-E90 Metabolic disorders
0.000 0.751 0.249
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.769 0.231
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.787 0.213
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.788 0.212
E83.8 Other disorders of mineral metabolism
0.000 0.788 0.212
E83.2 Disorders of zinc metabolism
0.000 0.788 0.212
E83.0 Disorders of copper metabolism
0.000 0.788 0.212
E13.8 With unspecified complications
0.000 0.788 0.211
E13.7 With multiple complications
0.000 0.788 0.211
E13.6 With other specified complications
0.000 0.788 0.211
E13.5 With peripheral circulatory complications
0.000 0.788 0.211
E13.4 With neurological complications
0.000 0.788 0.211
E13.2 With renal complications
0.000 0.788 0.211
E13.1 With ketoacidosis
0.000 0.788 0.211
E13.0 With coma
0.000 0.788 0.211
E40-E46 Malnutrition
0.000 0.790 0.210
E88 Other metabolic disorders
0.000 0.790 0.210
K90.3 Pancreatic steatorrhoea
0.000 0.793 0.207
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.793 0.207
K90.1 Tropical sprue
0.000 0.793 0.207
E13.3 With ophthalmic complications
0.000 0.793 0.207
E85 Amyloidosis
0.000 0.799 0.201
K90.8 Other intestinal malabsorption
0.000 0.801 0.199
E14.5 With peripheral circulatory complications
0.000 0.801 0.198
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.807 0.193
E14.7 With multiple complications
0.000 0.809 0.191
E14.6 With other specified complications
0.000 0.809 0.191
E14.2 Withrenal complications
0.000 0.809 0.191
E14.0 With coma
0.000 0.809 0.191
E16 Other disorders of pancreatic internal secretion
0.000 0.814 0.186
E14.4 With neurological complications
0.000 0.816 0.184
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.818 0.182
E46 Unspecified protein-energy malnutrition
0.000 0.819 0.181
E12.9 Without complications
0.000 0.821 0.179
E12.8 With unspecified complications
0.000 0.821 0.179
E12.7 With multiple complications
0.000 0.821 0.179
E12.6 With other specified complications
0.000 0.821 0.179
E12.5 With peripheral circulatory complications
0.000 0.821 0.179
E12.4 With neurological complications
0.000 0.821 0.179
E12.3 With ophthalmic complications
0.000 0.821 0.179
E12.2 With renal complications
0.000 0.821 0.179
E12.1 With ketoacidosis
0.000 0.821 0.179
E12.0 With coma
0.000 0.821 0.179
E84 Cystic fibrosis
0.000 0.821 0.178
E77 Disorders of glycoprotein metabolism
0.000 0.821 0.178
E76 Disorders of glycosaminoglycan metabolism
0.000 0.821 0.178
E72 Other disorders of amino-acid metabolism
0.000 0.821 0.178
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.821 0.178
E70 Disorders of aromatic amino-acid metabolism
0.000 0.821 0.178
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.821 0.178
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.823 0.177
E16.2 Hypoglycaemia, unspecified
0.000 0.827 0.173
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.829 0.171
E65-E68 Obesity and other hyperalimentation
0.000 0.829 0.171
E85.9 Amyloidosis, unspecified
0.000 0.832 0.168
E11 Non-insulin-dependent diabetes mellitus
0.000 0.836 0.164
E14.8 With unspecified complications
0.000 0.838 0.162
E14.1 With ketoacidosis
0.000 0.838 0.162
E79 Disorders of purine and pyrimidine metabolism
0.000 0.838 0.162
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.840 0.160
E88.8 Other specified metabolic disorders
0.000 0.840 0.160
E88.2 Lipomatosis, not elsewhere classified
0.000 0.842 0.158
E89.2 Postprocedural hypoparathyroidism
0.000 0.845 0.155
E15 Nondiabetic hypoglycaemic coma
0.000 0.847 0.153
E89.0 Postprocedural hypothyroidism
0.000 0.847 0.153
E85.4 Organ-limited amyloidosis
0.000 0.848 0.152
E88.3 Tumour lysis syndrome
0.000 0.848 0.151
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.849 0.151
E45 Retarded development following protein-energy malnutrition
0.000 0.849 0.151
E43 Unspecified severe protein-energy malnutrition
0.000 0.849 0.151
E42 Marasmic kwashiorkor
0.000 0.849 0.151
E41 Nutritional marasmus
0.000 0.849 0.151
E40 Kwashiorkor
0.000 0.849 0.151
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.850 0.149
E65 Localised adiposity
0.000 0.854 0.146
E85.8 Other amyloidosis
0.000 0.855 0.145
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.855 0.145
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.855 0.145
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.855 0.145
E89.4 Postprocedural ovarian failure
0.000 0.856 0.144
E74 Other disorders of carbohydrate metabolism
0.000 0.859 0.141
E11.5 With peripheral circulatory complications
0.000 0.860 0.140
E88.9 Metabolic disorder, unspecified
0.000 0.860 0.140
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.861 0.138
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.861 0.138
E89.5 Postprocedural testicular hypofunction
0.000 0.861 0.138
E89.1 Postprocedural hypoinsulinaemia
0.000 0.861 0.138
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.862 0.138
E83.3 Disorders of phosphorus metabolism
0.000 0.864 0.135
E80.4 Gilbert's syndrome
0.000 0.864 0.135
E85.3 Secondary systemic amyloidosis
0.000 0.865 0.135
E75.5 Other lipid storage disorders
0.000 0.865 0.134
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.866 0.134
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.866 0.134
E16.4 Abnormal secretion of gastrin
0.000 0.866 0.134
E16.3 Increased secretion of glucagon
0.000 0.866 0.134
E75.6 Lipid storage disorder, unspecified
0.000 0.869 0.131
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.869 0.131
E75.3 Sphingolipidosis, unspecified
0.000 0.869 0.131
E75.2 Other sphingolipidosis
0.000 0.869 0.131
E75.1 Other gangliosidosis
0.000 0.869 0.131
E75.0 GM2 gangliosidosis
0.000 0.869 0.131
E73 Lactose intolerance
0.001 0.871 0.129
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.872 0.128
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.872 0.128
E70.3 Albinism
0.000 0.872 0.128
E70.2 Disorders of tyrosine metabolism
0.000 0.872 0.128
E70.1 Other hyperphenylalaninaemias
0.000 0.872 0.128
E70.0 Classical phenylketonuria
0.000 0.872 0.128
E71.3 Disorders of fatty-acid metabolism
0.000 0.872 0.128
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.872 0.128
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.872 0.128
E71.0 Maple-syrup-urine disease
0.000 0.872 0.128
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.872 0.128
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.872 0.128
E72.5 Disorders of glycine metabolism
0.000 0.872 0.128
E72.4 Disorders of ornithine metabolism
0.000 0.872 0.128
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.872 0.128
E72.2 Disorders of urea cycle metabolism
0.000 0.872 0.128
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.872 0.128
E72.0 Disorders of amino-acid transport
0.000 0.872 0.128
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.872 0.128
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.872 0.128
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.872 0.128
E76.2 Other mucopolysaccharidoses
0.000 0.872 0.128
E76.1 Mucopolysaccharidosis, type II
0.000 0.872 0.128
E76.0 Mucopolysaccharidosis, type I
0.000 0.872 0.128
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.872 0.128
E77.8 Other disorders of glycoprotein metabolism
0.000 0.872 0.128
E77.1 Defects in glycoprotein degradation
0.000 0.872 0.128
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.872 0.128
E84.9 Cystic fibrosis, unspecified
0.000 0.872 0.128
E84.8 Cystic fibrosis with other manifestations
0.000 0.872 0.128
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.872 0.128
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.872 0.128
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.873 0.127
E80.5 Crigler-Najjar syndrome
0.000 0.873 0.127
E80.3 Defects of catalase and peroxydase
0.000 0.873 0.127
E80.1 Porphyria cutanea tarda
0.000 0.873 0.127
E80.0 Hereditary erythropoietic porphyria
0.000 0.873 0.127
E11.0 With coma
0.000 0.874 0.126
E11.8 With unspecified complications
0.000 0.877 0.123
E67 Other hyperalimentation
0.000 0.877 0.123
E68 Sequelae of hyperalimentation
0.000 0.877 0.123
E80.2 Other porphyria
0.000 0.878 0.122
E80.6 Other disorders of bilirubin metabolism
0.000 0.879 0.121
E11.1 With ketoacidosis
0.000 0.879 0.121
E11.7 With multiple complications
0.000 0.882 0.118
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.884 0.116
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.884 0.116
E79.1 Lesch-Nyhan syndrome
0.000 0.884 0.116
E83.4 Disorders of magnesium metabolism
0.000 0.884 0.116
E11.2 With renal complications
0.000 0.885 0.115
E11.6 With other specified complications
0.000 0.887 0.113
E11.4 With neurological complications
0.000 0.891 0.109
E44.1 Mild protein-energy malnutrition
0.000 0.891 0.108
E44.0 Moderate protein-energy malnutrition
0.000 0.891 0.108
E00-E07 Disorders of thyroid gland
0.000 0.895 0.105
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.897 0.103
E16.1 Other hypoglycaemia
0.000 0.898 0.101
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.899 0.101
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.899 0.101
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.899 0.101
E74.2 Disorders of galactose metabolism
0.000 0.899 0.101
E74.1 Disorders of fructose metabolism
0.000 0.899 0.101
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.900 0.100
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.901 0.099
E74.0 Glycogen storage disease
0.000 0.907 0.093
E73.8 Other lactose intolerance
0.001 0.907 0.092
E73.1 Secondary lactase deficiency
0.001 0.907 0.092
E73.0 Congenital lactase deficiency
0.001 0.907 0.092
K90.9 Intestinal malabsorption, unspecified
0.001 0.910 0.089
E67.8 Other specified hyperalimentation
0.000 0.912 0.088
E67.3 Hypervitaminosis D
0.000 0.912 0.088
E67.2 Megavitamin-B6 syndrome
0.000 0.912 0.088
E67.1 Hypercarotenaemia
0.000 0.912 0.088
E67.0 Hypervitaminosis A
0.000 0.912 0.088
E11.3 With ophthalmic complications
0.000 0.913 0.087
E89.3 Postprocedural hypopituitarism
0.000 0.916 0.084
E78.4 Other hyperlipidaemia
0.000 0.919 0.081
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.919 0.081
E50-E64 Other nutritional deficiencies
0.000 0.919 0.081
E07 Other disorders of thyroid
0.000 0.920 0.080
E04 Other non-toxic goitre
0.000 0.921 0.079
E83.5 Disorders of calcium metabolism
0.000 0.921 0.079
E78.6 Lipoprotein deficiency
0.000 0.922 0.078
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.923 0.077
E14.9 Without complications
0.000 0.923 0.077
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.925 0.075
E00 Congenital iodine-deficiency syndrome
0.000 0.925 0.075
E78.3 Hyperchylomicronaemia
0.000 0.926 0.074
E87.3 Alkalosis
0.000 0.926 0.074
E06 Thyroiditis
0.000 0.928 0.071
E78.1 Pure hyperglyceridaemia
0.000 0.930 0.070
E04.9 Non-toxic goitre, unspecified
0.000 0.931 0.069
E78.2 Mixed hyperlipidaemia
0.000 0.932 0.068
E07.9 Disorder of thyroid, unspecified
0.000 0.934 0.066
E87.0 Hyperosmolality and hypernatraemia
0.000 0.934 0.066
E03 Other hypothyroidism
0.000 0.934 0.066
E20-E35 Disorders of other endocrine glands
0.000 0.935 0.065
E66 Obesity
0.000 0.939 0.061
E04.0 Non-toxic diffuse goitre
0.000 0.940 0.060
E87.2 Acidosis
0.000 0.940 0.060
E87.7 Fluid overload
0.000 0.940 0.060
E03.8 Other specified hypothyroidism
0.000 0.941 0.059
E87.4 Mixed disorder of acid-base balance
0.000 0.942 0.058
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.942 0.058
E63 Other nutritional deficiencies
0.000 0.942 0.058
E56 Other vitamin deficiencies
0.000 0.942 0.058
E50 Vitamin A deficiency
0.000 0.942 0.058
E60 Dietary zinc deficiency
0.000 0.942 0.058
E59 Dietary selenium deficiency
0.000 0.942 0.058
E54 Ascorbic acid deficiency
0.000 0.942 0.058
E52 Niacin deficiency [pellagra]
0.000 0.942 0.058
E07.1 Dyshormogenetic goitre
0.000 0.942 0.058
E07.0 Hypersecretion of calcitonin
0.000 0.942 0.058
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.942 0.057
E58 Dietary calcium deficiency
0.000 0.942 0.057
E04.8 Other specified non-toxic goitre
0.000 0.943 0.057
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.946 0.054
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.946 0.054
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.946 0.054
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.946 0.054
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.946 0.054
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.946 0.054
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.946 0.054
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.946 0.054
E04.2 Non-toxic multinodular goitre
0.000 0.946 0.054
E51 Thiamine deficiency
0.000 0.946 0.053
E06.3 Autoimmune thyroiditis
0.000 0.947 0.053
E53 Deficiency of other B group vitamins
0.000 0.948 0.052
E06.5 Other chronic thyroiditis
0.000 0.948 0.051
E06.4 Drug-induced thyroiditis
0.000 0.948 0.051
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.948 0.051
E06.1 Subacute thyroiditis
0.000 0.948 0.051
E06.0 Acute thyroiditis
0.000 0.948 0.051
E07.8 Other specified disorders of thyroid
0.000 0.949 0.051
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.949 0.051
E20 Hypoparathyroidism
0.000 0.950 0.049
E26 Hyperaldosteronism
0.000 0.951 0.049
E28 Ovarian dysfunction
0.000 0.952 0.048
E03.5 Myxoedema coma
0.000 0.952 0.047
E03.4 Atrophy of thyroid (acquired)
0.000 0.952 0.047
E03.3 Postinfectious hypothyroidism
0.000 0.952 0.047
E03.1 Congenital hypothyroidism without goitre
0.000 0.952 0.047
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.952 0.047
E87.5 Hyperkalaemia
0.000 0.953 0.047
E29 Testicular dysfunction
0.000 0.953 0.047
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.953 0.047
E32 Diseases of thymus
0.000 0.953 0.047
E31 Polyglandular dysfunction
0.000 0.953 0.047
E30 Disorders of puberty, not elsewhere classified
0.000 0.953 0.047
E25 Adrenogenital disorders
0.000 0.953 0.047
E23 Hypofunction and other disorders of pituitary gland
0.000 0.954 0.046
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.954 0.046
E55 Vitamin D deficiency
0.000 0.955 0.045
E06.9 Thyroiditis, unspecified
0.000 0.955 0.045
E78.8 Other disorders of lipoprotein metabolism
0.000 0.956 0.044
E66.1 Drug-induced obesity
0.000 0.956 0.044
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.956 0.044
E73.9 Lactose intolerance, unspecified
0.001 0.956 0.043
E34 Other endocrine disorders
0.000 0.957 0.043
E23.2 Diabetes insipidus
0.000 0.957 0.043
E24 Cushing's syndrome
0.000 0.957 0.042
E28.2 Polycystic ovarian syndrome
0.000 0.958 0.042
R31 Unspecified haematuria
0.042 0.958 0.000
E66.0 Obesity due to excess calories
0.000 0.958 0.042
E50.9 Vitamin A deficiency, unspecified
0.000 0.958 0.042
E50.8 Other manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.958 0.042
E50.5 Vitamin A deficiency with night blindness
0.000 0.958 0.042
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.958 0.042
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.958 0.042
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.958 0.042
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.958 0.042
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.958 0.042
E56.9 Vitamin deficiency, unspecified
0.000 0.958 0.042
E56.8 Deficiency of other vitamins
0.000 0.958 0.042
E56.1 Deficiency of vitamin K
0.000 0.958 0.042
E56.0 Deficiency of vitamin E
0.000 0.958 0.042
E63.9 Nutritional deficiency, unspecified
0.000 0.958 0.042
E63.8 Other specified nutritional deficiencies
0.000 0.958 0.042
E63.1 Imbalance of constituents of food intake
0.000 0.958 0.042
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.958 0.042
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.958 0.042
E64.8 Sequelae of other nutritional deficiencies
0.000 0.958 0.042
E64.3 Sequelae of rickets
0.000 0.958 0.042
E64.2 Sequelae of vitamin C deficiency
0.000 0.958 0.042
E64.1 Sequelae of vitamin A deficiency
0.000 0.958 0.042
E64.0 Sequelae of protein-energy malnutrition
0.000 0.958 0.042
E04.1 Non-toxic single thyroid nodule
0.000 0.960 0.040
E51.9 Thiamine deficiency, unspecified
0.000 0.961 0.038
E51.8 Other manifestations of thiamine deficiency
0.000 0.961 0.038
E51.1 Beriberi
0.000 0.961 0.038
E20.9 Hypoparathyroidism, unspecified
0.000 0.962 0.038
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.962 0.038
E27 Other disorders of adrenal gland
0.000 0.962 0.038
E26.0 Primary hyperaldosteronism
0.000 0.963 0.037
E53.1 Pyridoxine deficiency
0.000 0.963 0.037
E53.0 Riboflavin deficiency
0.000 0.963 0.037
E53.9 Vitamin B deficiency, unspecified
0.000 0.963 0.037
E20.8 Other hypoparathyroidism
0.000 0.964 0.036
E20.1 Pseudohypoparathyroidism
0.000 0.964 0.036
E20.0 Idiopathic hypoparathyroidism
0.000 0.964 0.036
E24.2 Drug-induced Cushing's syndrome
0.000 0.965 0.035
E27.1 Primary adrenocortical insufficiency
0.000 0.965 0.035
E26.9 Hyperaldosteronism, unspecified
0.000 0.965 0.035
E26.8 Other hyperaldosteronism
0.000 0.965 0.035
E26.1 Secondary hyperaldosteronism
0.000 0.965 0.035
E28.9 Ovarian dysfunction, unspecified
0.000 0.965 0.035
E28.8 Other ovarian dysfunction
0.000 0.965 0.035
E28.1 Androgen excess
0.000 0.965 0.035
E28.0 Oestrogen excess
0.000 0.965 0.035
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.966 0.034
E51.2 Wernicke's encephalopathy
0.000 0.966 0.034
E29.1 Testicular hypofunction
0.000 0.966 0.034
E29.9 Testicular dysfunction, unspecified
0.000 0.966 0.034
E29.8 Other testicular dysfunction
0.000 0.966 0.034
E29.0 Testicular hyperfunction
0.000 0.966 0.034
E25.9 Adrenogenital disorder, unspecified
0.000 0.966 0.034
E25.8 Other adrenogenital disorders
0.000 0.966 0.034
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.966 0.034
E30.9 Disorder of puberty, unspecified
0.000 0.966 0.034
E30.8 Other disorders of puberty
0.000 0.966 0.034
E30.1 Precocious puberty
0.000 0.966 0.034
E30.0 Delayed puberty
0.000 0.966 0.034
E31.9 Polyglandular dysfunction, unspecified
0.000 0.966 0.034
E31.8 Other polyglandular dysfunction
0.000 0.966 0.034
E31.1 Polyglandular hyperfunction
0.000 0.966 0.034
E31.0 Autoimmune polyglandular failure
0.000 0.966 0.034
E32.9 Disease of thymus, unspecified
0.000 0.966 0.034
E32.8 Other diseases of thymus
0.000 0.966 0.034
E32.1 Abscess of thymus
0.000 0.966 0.034
E32.0 Persistent hyperplasia of thymus
0.000 0.966 0.034
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.966 0.034
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.966 0.034
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.966 0.034
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.966 0.033
E23.1 Drug-induced hypopituitarism
0.000 0.966 0.033
E23.7 Disorder of pituitary gland, unspecified
0.000 0.967 0.033
E05.8 Other thyrotoxicosis
0.000 0.967 0.033
E55.0 Rickets, active
0.000 0.967 0.032
E05.5 Thyroid crisis or storm
0.000 0.968 0.031
E05.4 Thyrotoxicosis factitia
0.000 0.968 0.031
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.968 0.031
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.968 0.031
E53.8 Deficiency of other specified B group vitamins
0.000 0.969 0.031
E61 Deficiency of other nutrient elements
0.001 0.969 0.030
E34.5 Androgen resistance syndrome
0.000 0.969 0.031
E34.4 Constitutional tall stature
0.000 0.969 0.031
E34.3 Short stature, not elsewhere classified
0.000 0.969 0.031
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.969 0.031
E34.1 Other hypersecretion of intestinal hormones
0.000 0.969 0.031
E24.8 Other Cushing's syndrome
0.000 0.969 0.031
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.969 0.031
E24.3 Ectopic ACTH syndrome
0.000 0.969 0.031
E24.1 Nelson's syndrome
0.000 0.969 0.031
E34.9 Endocrine disorder, unspecified
0.000 0.969 0.031
E34.8 Other specified endocrine disorders
0.000 0.970 0.030
E23.6 Other disorders of pituitary gland
0.000 0.971 0.029
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.971 0.029
E34.0 Carcinoid syndrome
0.000 0.972 0.028
E24.0 Pituitary-dependent Cushing's disease
0.000 0.973 0.027
E27.5 Adrenomedullary hyperfunction
0.000 0.973 0.027
E27.0 Other adrenocortical overactivity
0.000 0.973 0.027
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.973 0.027
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.973 0.027
E86 Volume depletion
0.000 0.976 0.024
E61.9 Deficiency of nutrient element, unspecified
0.001 0.977 0.022
E61.8 Deficiency of other specified nutrient elements
0.001 0.977 0.022
E61.7 Deficiency of multiple nutrient elements
0.001 0.977 0.022
E61.6 Vanadium deficiency
0.001 0.977 0.022
E61.5 Molybdenum deficiency
0.001 0.977 0.022
E61.4 Chromium deficiency
0.001 0.977 0.022
E61.3 Manganese deficiency
0.001 0.977 0.022
E61.0 Copper deficiency
0.001 0.977 0.022
E28.3 Primary ovarian failure
0.000 0.978 0.022
E24.9 Cushing's syndrome, unspecified
0.000 0.978 0.021
E27.2 Addisonian crisis
0.000 0.979 0.021
E21.3 Hyperparathyroidism, unspecified
0.000 0.979 0.021
E21.4 Other specified disorders of parathyroid gland
0.000 0.979 0.021
E21.2 Other hyperparathyroidism
0.000 0.979 0.021
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.979 0.021
E22 Hyperfunction of pituitary gland
0.000 0.980 0.020
E66.9 Obesity, unspecified
0.000 0.980 0.020
E55.9 Vitamin D deficiency, unspecified
0.000 0.980 0.020
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.981 0.019
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.981 0.019
K90-K93 Other diseases of the digestive system
0.000 0.982 0.018
E27.8 Other specified disorders of adrenal gland
0.000 0.982 0.018
E61.2 Magnesium deficiency
0.001 0.982 0.017
E23.0 Hypopituitarism
0.000 0.983 0.016
E27.9 Disorder of adrenal gland, unspecified
0.000 0.984 0.016
C71.2 Temporal lobe
0.016 0.984 0.000
C71 Malignant neoplasm of brain
0.016 0.984 0.000
C71.9 Brain, unspecified
0.015 0.985 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.985 0.015
E22.8 Other hyperfunction of pituitary gland
0.000 0.985 0.015
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.987 0.013
E22.1 Hyperprolactinaemia
0.000 0.987 0.013
C71.1 Frontal lobe
0.013 0.987 0.000
C71.3 Parietal lobe
0.013 0.987 0.000
C71.7 Brain stem
0.012 0.988 0.000
C71.0 Cerebrum, except lobes and ventricles
0.012 0.988 0.000
C71.6 Cerebellum
0.011 0.989 0.000
C71.5 Cerebral ventricle
0.011 0.989 0.000
C71.8 Overlapping lesion of brain
0.011 0.989 0.000
E21.0 Primary hyperparathyroidism
0.000 0.989 0.011
M41.9 Scoliosis, unspecified
0.011 0.989 0.000
E87.6 Hypokalaemia
0.000 0.990 0.010
M41.96 Scoliosis, unspecified (Lumbar region)
0.010 0.990 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.990 0.010
K93.1 Megacolon in Chagas' disease
0.000 0.990 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.990 0.010
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.010 0.990 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.010 0.990 0.000
E22.0 Acromegaly and pituitary gigantism
0.001 0.990 0.009
M41.94 Scoliosis, unspecified (Thoracic region)
0.010 0.990 0.000
C71.4 Occipital lobe
0.010 0.990 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.990 0.010
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.009 0.991 0.000
E66.8 Other obesity
0.000 0.991 0.009
G44.2 Tension-type headache
0.009 0.991 0.000
E61.1 Iron deficiency
0.001 0.991 0.007
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.008 0.992 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.008 0.992 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.008 0.992 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.008 0.992 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.992 0.007
C69 Malignant neoplasm of eye and adnexa
0.008 0.992 0.000
C70 Malignant neoplasm of meninges
0.007 0.993 0.000
G31.8 Other specified degenerative diseases of nervous system
0.000 0.993 0.007
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.007 0.993 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.007 0.993 0.000
C69.9 Eye, unspecified
0.007 0.993 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.006 0.994 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.994 0.006
C69.3 Choroid
0.006 0.994 0.000
G31.0 Circumscribed brain atrophy
0.000 0.994 0.006
G54.9 Nerve root and plexus disorder, unspecified
0.006 0.994 0.000
C70.0 Cerebral meninges
0.006 0.994 0.000
C69.8 Overlapping lesion of eye and adnexa
0.006 0.994 0.000
C69.5 Lachrymal gland and duct
0.006 0.994 0.000
C69.4 Ciliary body
0.006 0.994 0.000
C69.2 Retina
0.006 0.994 0.000
C69.1 Cornea
0.006 0.994 0.000
C69.6 Orbit
0.006 0.994 0.000
C69.0 Conjunctiva
0.005 0.994 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.994 0.006
C70.9 Meninges, unspecified
0.005 0.995 0.000
C70.1 Spinal meninges
0.005 0.995 0.000
N04.9 Unspecified
0.000 0.995 0.005
M79.10 Myalgia (Multiple sites)
0.005 0.995 0.000
M41 Scoliosis
0.005 0.995 0.000
C72.9 Central nervous system, unspecified
0.005 0.995 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.005 0.995 0.000
C72.5 Other and unspecified cranial nerves
0.005 0.995 0.000
C72.4 Acoustic nerve
0.005 0.995 0.000
C72.3 Optic nerve
0.005 0.995 0.000
C72.2 Olfactory nerve
0.005 0.995 0.000
C72.1 Cauda equina
0.005 0.995 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.995 0.005
C72.0 Spinal cord
0.004 0.995 0.000
K62.5 Haemorrhage of anus and rectum
0.005 0.995 0.000
M67.8 Other specified disorders of synovium and tendon
0.000 0.995 0.005
G44 Other headache syndromes
0.004 0.996 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.004 0.996 0.000
R52.1 Chronic intractable pain
0.004 0.996 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.996 0.004
G44.8 Other specified headache syndromes
0.004 0.996 0.000
M22.2 Patellofemoral disorders
0.004 0.996 0.000
M41.5 Other secondary scoliosis
0.004 0.996 0.000
M41.4 Neuromuscular scoliosis
0.004 0.996 0.000
M41.3 Thoracogenic scoliosis
0.004 0.996 0.000
M41.2 Other idiopathic scoliosis
0.004 0.996 0.000
M41.1 Juvenile idiopathic scoliosis
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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