TreeWAS – Variant ID: rs374186

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter VI Diseases of the nervous system	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
E11 Non-insulin-dependent diabetes mellitus	0.998	0.002
G90-G99 Other disorders of the nervous system	0.997	0.003
E65-E68 Obesity and other hyperalimentation	0.995	0.005
I30-I52 Other forms of heart disease	0.995	0.005
E66 Obesity	0.989	0.011
E66.8 Other obesity	0.987	0.013
E10 Insulin-dependent diabetes mellitus	0.974	0.026
I60-I69 Cerebrovascular diseases	0.972	0.028
G99 Other disorders of nervous system in diseases classified elsewhere	0.959	0.041
I44 Atrioventricular and left bundle-branch block	0.955	0.045
Chapter VII Diseases of the eye and adnexa	0.951	0.049
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.950	0.050
E14 Unspecified diabetes mellitus	0.946	0.054
E11.3 With ophthalmic complications	0.942	0.058
G00-G09 Inflammatory diseases of the central nervous system	0.938	0.062
E11.5 With peripheral circulatory complications	0.937	0.063
I49 Other cardiac arrhythmias	0.936	0.064
E11.4 With neurological complications	0.932	0.068
I69 Sequelae of cerebrovascular disease	0.932	0.068
G93 Other disorders of brain	0.930	0.070
G95 Other diseases of spinal cord	0.927	0.073
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.924	0.076
H25-H28 Disorders of lens	0.923	0.077
G50-G59 Nerve, nerve root and plexus disorders	0.921	0.079
I51 Complications and ill-defined descriptions of heart disease	0.915	0.085
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.915	0.085
H26 Other cataract	0.912	0.088
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.909	0.091
S00-S09 Injuries to the head	0.908	0.092
Chapter XII Diseases of the skin and subcutaneous tissue	0.902	0.098
G99.2 Myelopathy in diseases classified elsewhere	0.902	0.098
I67 Other cerebrovascular diseases	0.901	0.099
I70-I79 Diseases of arteries, arterioles and capillaries	0.898	0.102
H26.9 Cataract, unspecified	0.894	0.106
E14.9 Without complications	0.890	0.110
G40-G47 Episodic and paroxysmal disorders	0.889	0.111
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.888	0.112
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.883	0.117
I46 Cardiac arrest	0.874	0.126
I49.8 Other specified cardiac arrhythmias	0.870	0.130
I44.0 Atrioventricular block, first degree	0.868	0.132
G20-G26 Extrapyramidal and movement disorders	0.868	0.132
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.860	0.140
Chapter XX External causes of morbidity and mortality	0.858	0.142
I44.1 Atrioventricular block, second degree	0.855	0.145
E10.9 Without complications	0.852	0.148
I51.9 Heart disease, unspecified	0.850	0.150
G70-G73 Diseases of myoneural junction and muscle	0.848	0.152
M50-M54 Other dorsopathies	0.845	0.155
H26.4 After-cataract	0.844	0.156
G59 Mononeuropathy in diseases classified elsewhere	0.843	0.157
I26 Pulmonary embolism	0.842	0.158
G30-G32 Other degenerative diseases of the nervous system	0.841	0.159
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.838	0.162
G95.2 Cord compression, unspecified	0.835	0.165
E10.5 With peripheral circulatory complications	0.834	0.166
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.831	0.169
E10.4 With neurological complications	0.831	0.169
I77 Other disorders of arteries and arterioles	0.830	0.170
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.830	0.170
Chapter V Mental and behavioural disorders	0.829	0.171
I42 Cardiomyopathy	0.829	0.171
L20-L30 Dermatitis and eczema	0.828	0.172
E20-E35 Disorders of other endocrine glands	0.826	0.174
H30-H36 Disorders of choroid and retina	0.821	0.179
E10.0 With coma	0.819	0.181
G40 Epilepsy	0.818	0.182
I67.8 Other specified cerebrovascular diseases	0.814	0.186
S00 Superficial injury of head	0.814	0.186
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.814	0.186
I50 Heart failure	0.813	0.187
M70-M79 Other soft tissue disorders	0.810	0.190
M54 Dorsalgia	0.808	0.192
G95.9 Disease of spinal cord, unspecified	0.808	0.192
I49.5 Sick sinus syndrome	0.807	0.193
E11.6 With other specified complications	0.807	0.193
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.806	0.194
Q80-Q89 Other congenital malformations	0.805	0.195
I77.9 Disorder of arteries and arterioles, unspecified	0.802	0.198
W00-W19 Falls	0.801	0.199
I69.3 Sequelae of cerebral infarction	0.799	0.201
S50-S59 Injuries to the elbow and forearm	0.798	0.202
E66.2 Extreme obesity with alveolar hypoventilation	0.797	0.203
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.796	0.204
Chapter I Certain infectious and parasitic diseases	0.796	0.204
E65 Localised adiposity	0.795	0.205
Chapter XXII Codes for special purposes	0.795	0.205
G50 Disorders of trigeminal nerve	0.794	0.206
E66.0 Obesity due to excess calories	0.790	0.210
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.789	0.211
I10-I15 Hypertensive diseases	0.788	0.212
E13 Other specified diabetes mellitus	0.787	0.213
G03 Meningitis due to other and unspecified causes	0.787	0.213
G59.0 Diabetic mononeuropathy	0.787	0.213
M60-M63 Disorders of muscles	0.787	0.213
G63 Polyneuropathy in diseases classified elsewhere	0.783	0.217
G94 Other disorders of brain in diseases classified elsewhere	0.782	0.218
G00 Bacterial meningitis, not elsewhere classified	0.781	0.219
I37 Pulmonary valve disorders	0.780	0.220
E11.9 Without complications	0.779	0.221
I67.9 Cerebrovascular disease, unspecified	0.778	0.221
S90-S99 Injuries to the ankle and foot	0.778	0.222
S06 Intracranial injury	0.774	0.226
E11.0 With coma	0.771	0.229
S01 Open wound of head	0.769	0.231
H55-H59 Other disorders of eye and adnexa	0.769	0.231
L80-L99 Other disorders of the skin and subcutaneous tissue	0.769	0.231
G93.9 Disorder of brain, unspecified	0.768	0.232
M79 Other soft tissue disorders, not elsewhere classified	0.766	0.234
Q50-Q56 Congenital malformations of genital organs	0.764	0.236
G93.5 Compression of brain	0.764	0.236
R47-R49 Symptoms and signs involving speech and voice	0.764	0.236
L29 Pruritus	0.763	0.237
E14.3 With ophthalmic complications	0.761	0.239
F00-F09 Organic, including symptomatic, mental disorders	0.761	0.239
M54.5 Low back pain	0.761	0.239
E16 Other disorders of pancreatic internal secretion	0.759	0.241
G60 Hereditary and idiopathic neuropathy	0.755	0.245
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.754	0.246
I45 Other conduction disorders	0.754	0.246
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.753	0.247
T15-T19 Effects of foreign body entering through natural orifice	0.752	0.247
E11.2 With renal complications	0.751	0.249
I46.0 Cardiac arrest with successful resuscitation	0.750	0.250
E10.1 With ketoacidosis	0.750	0.250
I42.2 Other hypertrophic cardiomyopathy	0.747	0.252
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.746	0.254
G93.3 Postviral fatigue syndrome	0.746	0.254
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.746	0.254
I67.2 Cerebral atherosclerosis	0.745	0.255
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.743	0.257
I33 Acute and subacute endocarditis	0.742	0.257
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.741	0.259
G09 Sequelae of inflammatory diseases of central nervous system	0.738	0.262
H46-H48 Disorders of optic nerve and visual pathways	0.737	0.263
G90 Disorders of autonomic nervous system	0.736	0.264
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.736	0.264
M86-M90 Other osteopathies	0.735	0.265
G24 Dystonia	0.735	0.265
S01.0 Open wound of scalp	0.734	0.266
T93 Sequelae of injuries of lower limb	0.733	0.267
R47 Speech disturbances, not elsewhere classified	0.732	0.268
H27 Other disorders of lens	0.731	0.269
Chapter XV Pregnancy, childbirth and the puerperium	0.731	0.269
M54.3 Sciatica	0.730	0.270
S80-S89 Injuries to the knee and lower leg	0.729	0.271
G93.8 Other specified disorders of brain	0.728	0.272
E00-E07 Disorders of thyroid gland	0.728	0.272
T79-T79 Certain early complications of trauma	0.727	0.273
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.726	0.274
Q38-Q45 Other congenital malformations of the digestive system	0.726	0.274
I64 Stroke, not specified as haemorrhage or infarction	0.726	0.274
I49.0 Ventricular fibrillation and flutter	0.725	0.275
H43-H45 Disorders of vitreous body and globe	0.725	0.275
I12 Hypertensive renal disease	0.724	0.276
G62 Other polyneuropathies	0.723	0.277
I36 Nonrheumatic tricuspid valve disorders	0.723	0.277
E28 Ovarian dysfunction	0.719	0.281
I44.3 Other and unspecified atrioventricular block	0.718	0.282
G40.8 Other epilepsy	0.718	0.282
I44.6 Other and unspecified fascicular block	0.718	0.282
I44.2 Atrioventricular block, complete	0.717	0.282
M54.59 Low back pain (Site unspecified)	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
H35 Other retinal disorders	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.284
E11.8 With unspecified complications	0.716	0.284
E11.7 With multiple complications	0.716	0.284
E11.1 With ketoacidosis	0.716	0.284
I63 Cerebral infarction	0.716	0.284
G53 Cranial nerve disorders in diseases classified elsewhere	0.715	0.285
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.715	0.285
I51.7 Cardiomegaly	0.715	0.285
G98 Other disorders of nervous system, not elsewhere classified	0.715	0.285
G92 Toxic encephalopathy	0.715	0.285
M62 Other disorders of muscle	0.714	0.286
L40-L45 Papulosquamous disorders	0.713	0.287
E67 Other hyperalimentation	0.713	0.287
E68 Sequelae of hyperalimentation	0.713	0.287
I52 Other heart disorders in diseases classified elsewhere	0.713	0.287
I48 Atrial fibrillation and flutter	0.713	0.287
I43 Cardiomyopathy in diseases classified elsewhere	0.713	0.287
I41 Myocarditis in diseases classified elsewhere	0.713	0.287
I40 Acute myocarditis	0.713	0.287
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.713	0.287
I32 Pericarditis in diseases classified elsewhere	0.713	0.287
M05-M14 Inflammatory polyarthropathies	0.711	0.289
E66.1 Drug-induced obesity	0.709	0.291
G93.4 Encephalopathy, unspecified	0.709	0.291
I72 Other aneurysm	0.708	0.292
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.708	0.292
S50 Superficial injury of forearm	0.706	0.294
M91-M94 Chondropathies	0.705	0.295
M79.0 Rheumatism, unspecified	0.704	0.296
G50.0 Trigeminal neuralgia	0.703	0.297
G45 Transient cerebral ischaemic attacks and related syndromes	0.702	0.298
G93.2 Benign intracranial hypertension	0.702	0.298
I27 Other pulmonary heart diseases	0.701	0.299
I46.9 Cardiac arrest, unspecified	0.701	0.299
H36 Retinal disorders in diseases classified elsewhere	0.701	0.299
G04 Encephalitis, myelitis and encephalomyelitis	0.700	0.300
I62 Other nontraumatic intracranial haemorrhage	0.700	0.300
M50 Cervical disk disorders	0.700	0.300
L97 Ulcer of lower limb, not elsewhere classified	0.699	0.301
E10.8 With unspecified complications	0.698	0.302
E10.7 With multiple complications	0.698	0.302
E10.6 With other specified complications	0.698	0.302
E10.2 With renal complications	0.698	0.302
R47.8 Other and unspecified speech disturbances	0.698	0.302
I42.1 Obstructive hypertrophic cardiomyopathy	0.698	0.302
L89 Decubitus ulcer	0.698	0.302
I68 Cerebrovascular disorders in diseases classified elsewhere	0.697	0.303
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.697	0.303
E05 Thyrotoxicosis [hyperthyroidism]	0.697	0.303
G44 Other headache syndromes	0.696	0.304
G71 Primary disorders of muscles	0.695	0.305
G63.2 Diabetic polyneuropathy	0.693	0.307
I49.9 Cardiac arrhythmia, unspecified	0.692	0.308
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.692	0.308
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.691	0.309
I30 Acute pericarditis	0.691	0.309
S00.9 Superficial injury of head, part unspecified	0.690	0.310
G30 Alzheimer's disease	0.688	0.312
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.687	0.312
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.687	0.312
E16.2 Hypoglycaemia, unspecified	0.687	0.313
M13 Other arthritis	0.686	0.314
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.686	0.314
S10-S19 Injuries to the neck	0.686	0.314
I44.5 Left posterior fascicular block	0.685	0.315
I44.4 Left anterior fascicular block	0.685	0.315
Q20-Q28 Congenital malformations of the circulatory system	0.684	0.316
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.683	0.317
I69.1 Sequelae of intracerebral haemorrhage	0.683	0.317
I50.9 Heart failure, unspecified	0.683	0.317
L29.9 Pruritus, unspecified	0.682	0.318
H34 Retinal vascular occlusions	0.682	0.318
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.681	0.318
I73 Other peripheral vascular diseases	0.681	0.318
T33-T35 Frostbite	0.681	0.319
T26-T28 Burns and corrosions confined to eye and internal organs	0.681	0.319
T20-T25 Burns and corrosions of external body surface, specified by site	0.681	0.319
T00-T07 Injuries involving multiple body regions	0.681	0.319
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.681	0.319
M80-M85 Disorders of bone density and structure	0.681	0.319
X58-X59 Accidental exposure to other and unspecified factors	0.681	0.319
G20 Parkinson's disease	0.680	0.320
S01.9 Open wound of head, part unspecified	0.679	0.321
G03.9 Meningitis, unspecified	0.679	0.321
E14.8 With unspecified complications	0.678	0.322
E14.7 With multiple complications	0.678	0.322
E14.6 With other specified complications	0.678	0.322
E14.5 With peripheral circulatory complications	0.678	0.322
E14.4 With neurological complications	0.678	0.322
E14.2 Withrenal complications	0.678	0.322
E14.1 With ketoacidosis	0.678	0.322
E14.0 With coma	0.678	0.322
E05.9 Thyrotoxicosis, unspecified	0.678	0.322
R30-R39 Symptoms and signs involving the urinary system	0.678	0.322
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.676	0.324
H40-H42 Glaucoma	0.676	0.324
L27 Dermatitis due to substances taken internally	0.674	0.326
G06 Intracranial and intraspinal abscess and granuloma	0.673	0.327
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.673	0.327
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.673	0.327
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.673	0.327
G01 Meningitis in bacterial diseases classified elsewhere	0.673	0.327
M72 Fibroblastic disorders	0.673	0.327
B25-B34 Other viral diseases	0.672	0.328
Chapter VIII Diseases of the ear and mastoid process	0.672	0.328
X60-X84 Intentional self-harm	0.672	0.328
W50-W64 Exposure to animate mechanical forces	0.672	0.328
M79.09 Rheumatism, unspecified (Site unspecified)	0.671	0.329
I49.2 Junctional premature depolarisation	0.671	0.329
I45.6 Preexcitation syndrome	0.670	0.329
F80-F89 Disorders of psychological development	0.670	0.330
E29 Testicular dysfunction	0.669	0.331
M13.9 Arthritis, unspecified	0.669	0.331
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.668	0.332
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.668	0.332
G00.1 Pneumococcal meningitis	0.668	0.332
W06 Fall involving bed	0.667	0.333
G93.7 Reye's syndrome	0.667	0.333
H21 Other disorders of iris and ciliary body	0.667	0.333
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.666	0.334
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.665	0.335
Q60-Q64 Congenital malformations of the urinary system	0.665	0.335
G95.1 Vascular myelopathies	0.665	0.335
G95.0 Syringomyelia and syringobulbia	0.665	0.335
I12.0 Hypertensive renal disease with renal failure	0.665	0.335
F00 Dementia in Alzheimer's disease	0.664	0.336
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.663	0.337
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.663	0.337
Q35-Q37 Cleft lip and cleft palate	0.663	0.337
Q30-Q34 Congenital malformations of the respiratory system	0.663	0.337
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.663	0.337
R32 Unspecified urinary incontinence	0.663	0.337
M62.8 Other specified disorders of muscle	0.662	0.338
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.662	0.338
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.661	0.339
M00-M03 Infectious arthropathies	0.661	0.339
X40-X49 Accidental poisoning by and exposure to noxious substances	0.660	0.340
G52 Disorders of other cranial nerves	0.660	0.340
T90 Sequelae of injuries of head	0.660	0.340
I77.0 Arteriovenous fistula, acquired	0.659	0.341
Q85 Phakomatoses, not elsewhere classified	0.659	0.341
H55 Nystagmus and other irregular eye movements	0.659	0.341
S30 Superficial injury of abdomen, lower back and pelvis	0.658	0.342
G93.0 Cerebral cysts	0.658	0.342
L50-L54 Urticaria and erythema	0.658	0.342
I51.6 Cardiovascular disease, unspecified	0.656	0.344
I51.5 Myocardial degeneration	0.656	0.344
I51.3 Intracardiac thrombosis, not elsewhere classified	0.656	0.344
I51.2 Rupture of papillary muscle, not elsewhere classified	0.656	0.344
I51.0 Cardiac septal defect, acquired	0.656	0.344
I28 Other diseases of pulmonary vessels	0.656	0.344
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.655	0.344
I51.4 Myocarditis, unspecified	0.655	0.344
L29.2 Pruritus vulvae	0.655	0.345
I70 Atherosclerosis	0.654	0.345
H26.3 Drug-induced cataract	0.654	0.346
H26.2 Complicated cataract	0.654	0.346
H26.1 Traumatic cataract	0.654	0.346
H26.0 Infantile, juvenile and presenile cataract	0.654	0.346
G93.1 Anoxic brain damage, not elsewhere classified	0.653	0.346
W02.9 Unspecified place	0.653	0.347
M50.1 Cervical disk disorder with radiculopathy	0.653	0.347
G64 Other disorders of peripheral nervous system	0.652	0.348
S08 Traumatic amputation of part of head	0.651	0.349
S07 Crushing injury of head	0.651	0.349
S04 Injury of cranial nerves	0.651	0.349
S03 Dislocation, sprain and strain of joints and ligaments of head	0.651	0.349
W05 Fall involving wheelchair	0.650	0.350
M54.4 Lumbago with sciatica	0.649	0.351
G93.6 Cerebral oedema	0.649	0.351
I49.1 Atrial premature depolarisation	0.648	0.352
L89.9 Decubitus ulcer and pressure area, unspecified	0.648	0.352
G72 Other myopathies	0.647	0.353
S06.5 Traumatic subdural haemorrhage	0.647	0.353
L10-L14 Bullous disorders	0.647	0.353
V10-V19 Pedal cyclist injured in transport accident	0.647	0.353
I67.7 Cerebral arteritis, not elsewhere classified	0.646	0.354
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.646	0.354
I67.5 Moyamoya disease	0.646	0.354
I67.4 Hypertensive encephalopathy	0.646	0.354
I67.3 Progressive vascular leukoencephalopathy	0.646	0.354
I67.0 Dissection of cerebral arteries, nonruptured	0.646	0.354
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.646	0.354
W07 Fall involving chair	0.645	0.355
M79.7 Fibromyalgia	0.645	0.355
S00.8 Superficial injury of other parts of head	0.644	0.356
G70 Myasthenia gravis and other myoneural disorders	0.643	0.357
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.643	0.357
M54.36 Sciatica (Lumbar region)	0.643	0.357
S09 Other and unspecified injuries of head	0.643	0.357
E28.2 Polycystic ovarian syndrome	0.643	0.357
I50.1 Left ventricular failure	0.642	0.358
O16 Unspecified maternal hypertension	0.641	0.359
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.641	0.359
W11 Fall on and from ladder	0.641	0.359
G58 Other mononeuropathies	0.640	0.359
S54 Injury of nerves at forearm level	0.640	0.359
S00.7 Multiple superficial injuries of head	0.640	0.360
S50.0 Contusion of elbow	0.639	0.361
G24.9 Dystonia, unspecified	0.639	0.361
G25 Other extrapyramidal and movement disorders	0.638	0.362
G46 Vascular syndromes of brain in cerebrovascular diseases	0.637	0.362
S05 Injury of eye and orbit	0.637	0.362
I49.3 Ventricular premature depolarisation	0.637	0.363
I42.8 Other cardiomyopathies	0.637	0.363
S86 Injury of muscle and tendon at lower leg level	0.635	0.365
E13.9 Without complications	0.635	0.365
A50-A64 Infections with a predominantly sexual mode of transmission	0.634	0.366
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.634	0.366
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.634	0.366
T36-T50 Poisoning by drugs, medicaments and biological substances	0.634	0.366
S02 Fracture of skull and facial bones	0.632	0.367
G41 Status epilepticus	0.632	0.367
Y60-Y69 Misadventures to patients during surgical and medical care	0.632	0.368
G80-G83 Cerebral palsy and other paralytic syndromes	0.631	0.369
Q00-Q07 Congenital malformations of the nervous system	0.629	0.371
G94.1 Hydrocephalus in neoplastic disease	0.629	0.371
R20 Disturbances of skin sensation	0.628	0.372
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.628	0.372
I11 Hypertensive heart disease	0.627	0.373
M77 Other enthesopathies	0.627	0.373
I46.1 Sudden cardiac death, so described	0.627	0.373
I37.1 Pulmonary valve insufficiency	0.625	0.374
F10 Mental and behavioural disorders due to use of alcohol	0.625	0.375
H10-H13 Disorders of conjunctiva	0.623	0.376
S00.0 Superficial injury of scalp	0.623	0.377
Q89 Other congenital malformations, not elsewhere classified	0.623	0.377
L91 Hypertrophic disorders of skin	0.623	0.377
T93.2 Sequelae of other fractures of lower limb	0.623	0.377
I35 Nonrheumatic aortic valve disorders	0.623	0.377
G23 Other degenerative diseases of basal ganglia	0.622	0.378
G21 Secondary Parkinsonism	0.622	0.378
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.622	0.378
G22 Parkinsonism in diseases classified elsewhere	0.622	0.378
M79.9 Soft tissue disorder, unspecified	0.621	0.378
R25 Abnormal involuntary movements	0.622	0.378
G91 Hydrocephalus	0.621	0.379
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.621	0.379
L20 Atopic dermatitis	0.620	0.380
T98 Sequelae of other and unspecified effects of external causes	0.620	0.380
I78 Diseases of capillaries	0.620	0.380
R91 Abnormal findings on diagnostic imaging of lung	0.619	0.381
G12 Spinal muscular atrophy and related syndromes	0.619	0.381
I73.9 Peripheral vascular disease, unspecified	0.619	0.381
F03 Unspecified dementia	0.618	0.382
G95.8 Other specified diseases of spinal cord	0.618	0.382
I63.8 Other cerebral infarction	0.618	0.382
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.617	0.383
E10.3 With ophthalmic complications	0.617	0.383
E15 Nondiabetic hypoglycaemic coma	0.616	0.384
O80-O84 Delivery	0.616	0.384
Y35-Y36 Legal intervention and operations of war	0.615	0.385
Y10-Y34 Event of undetermined intent	0.615	0.385
Y00-Y09 Assault	0.615	0.385
X85-X99 Assault	0.615	0.385
X50-X57 Overexertion, travel and privation	0.615	0.385
X30-X39 Exposure to forces of nature	0.615	0.385
X20-X29 Contact with venomous animals and plants	0.615	0.385
X10-X19 Contact with heat and hot substances	0.615	0.385
X00-X09 Exposure to smoke, fire and flames	0.615	0.385
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.615	0.385
W75-W84 Other accidental threats to breathing	0.615	0.385
W65-W74 Accidental drowning and submersion	0.615	0.385
V98-V99 Other and unspecified transport accidents	0.615	0.385
V95-V97 Air and space transport accidents	0.615	0.385
V90-V94 Water transport accidents	0.615	0.385
V70-V79 Bus occupant injured in transport accident	0.615	0.385
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.615	0.385
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.615	0.385
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.615	0.385
V01-V09 Pedestrian injured in transport accident	0.615	0.385
M54.50 Low back pain (Multiple sites in spine)	0.615	0.385
M13.99 Arthritis, unspecified (Site unspecified)	0.615	0.385
H36.0 Diabetic retinopathy	0.614	0.386
M13.96 Arthritis, unspecified (Lower leg)	0.613	0.387
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.613	0.387
B50-B64 Protozoal diseases	0.611	0.388
I44.7 Left bundle-branch block, unspecified	0.612	0.388
R20.2 Paraesthesia of skin	0.611	0.389
G60.8 Other hereditary and idiopathic neuropathies	0.611	0.389
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.611	0.389
G96 Other disorders of central nervous system	0.610	0.389
G11 Hereditary ataxia	0.610	0.390
V40-V49 Car occupant injured in transport accident	0.609	0.391
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.608	0.392
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.608	0.392
B20-B24 Human immunodeficiency virus [HIV] disease	0.608	0.392
B95-B98 Bacterial, viral and other infectious agents	0.606	0.394
Y52 Agents primarily affecting the cardiovascular system	0.606	0.394
G62.9 Polyneuropathy, unspecified	0.605	0.395
F99-F99 Unspecified mental disorder	0.605	0.395
I74 Arterial embolism and thrombosis	0.605	0.395
M71 Other bursopathies	0.605	0.395
L90 Atrophic disorders of skin	0.605	0.395
G59.8 Other mononeuropathies in diseases classified elsewhere	0.604	0.396
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.604	0.396
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.603	0.396
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.603	0.397
G61 Inflammatory polyneuropathy	0.602	0.397
H35.3 Degeneration of macula and posterior pole	0.602	0.398
E70-E90 Metabolic disorders	0.602	0.398
T93.1 Sequelae of fracture of femur	0.601	0.398
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.601	0.399
T93.8 Sequelae of other specified injuries of lower limb	0.600	0.400
I05-I09 Chronic rheumatic heart diseases	0.599	0.401
G51 Facial nerve disorders	0.599	0.401
E40-E46 Malnutrition	0.598	0.402
M54.39 Sciatica (Site unspecified)	0.598	0.402
I69.0 Sequelae of subarachnoid haemorrhage	0.597	0.403
S20-S29 Injuries to the thorax	0.597	0.403
H90-H95 Other disorders of ear	0.597	0.403
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.597	0.403
H47 Other disorders of optic [2nd] nerve and visual pathways	0.596	0.403
F00.9 Dementia in Alzheimer's disease, unspecified	0.595	0.405
I77.5 Necrosis of artery	0.595	0.405
I77.4 Coeliac artery compression syndrome	0.595	0.405
I77.3 Arterial fibromuscular dysplasia	0.595	0.405
I77.2 Rupture of artery	0.595	0.405
T95 Sequelae of burns, corrosions and frostbite	0.595	0.405
T94 Sequelae of injuries involving multiple and unspecified body regions	0.595	0.405
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.595	0.405
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.595	0.405
R47.0 Dysphasia and aphasia	0.595	0.405
M76 Enthesopathies of lower limb, excluding foot	0.595	0.405
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.594	0.405
F70-F79 Mental retardation	0.594	0.405
I42.7 Cardiomyopathy due to drugs and other external agents	0.594	0.406
I42.6 Alcoholic cardiomyopathy	0.594	0.406
I42.5 Other restrictive cardiomyopathy	0.594	0.406

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations