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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3749970
log Bayes Factor = 47.4542
Chromosome 6   position 29,342,825  (GRCh37) Explore rs3749970 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E10 Insulin-dependent diabetes mellitus
0.000 0.007 0.993
E10.9 Without complications
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.014 0.986
E16 Other disorders of pancreatic internal secretion
0.000 0.016 0.984
E16.2 Hypoglycaemia, unspecified
0.000 0.016 0.984
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.017 0.983
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.017 0.983
E00-E07 Disorders of thyroid gland
0.000 0.019 0.981
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.036 0.964
E10.3 With ophthalmic complications
0.000 0.046 0.954
E10.2 With renal complications
0.000 0.058 0.942
E10.4 With neurological complications
0.000 0.085 0.915
E16.1 Other hypoglycaemia
0.000 0.178 0.822
E13 Other specified diabetes mellitus
0.000 0.183 0.817
E05.8 Other thyrotoxicosis
0.000 0.203 0.797
E10.1 With ketoacidosis
0.000 0.205 0.795
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.215 0.785
E14 Unspecified diabetes mellitus
0.000 0.262 0.738
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
E10.7 With multiple complications
0.000 0.291 0.709
E13.9 Without complications
0.000 0.292 0.708
E12 Malnutrition-related diabetes mellitus
0.000 0.293 0.707
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.295 0.705
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.295 0.705
E16.4 Abnormal secretion of gastrin
0.000 0.295 0.705
E16.3 Increased secretion of glucagon
0.000 0.295 0.705
E15 Nondiabetic hypoglycaemic coma
0.000 0.295 0.705
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.297 0.703
E00 Congenital iodine-deficiency syndrome
0.000 0.297 0.703
E10.6 With other specified complications
0.000 0.298 0.702
E10.0 With coma
0.000 0.306 0.694
E40-E46 Malnutrition
0.000 0.336 0.664
E14.3 With ophthalmic complications
0.000 0.363 0.637
E14.6 With other specified complications
0.000 0.409 0.591
E13.8 With unspecified complications
0.000 0.414 0.586
E13.7 With multiple complications
0.000 0.414 0.586
E13.6 With other specified complications
0.000 0.414 0.586
E13.5 With peripheral circulatory complications
0.000 0.414 0.586
E13.4 With neurological complications
0.000 0.414 0.586
E13.2 With renal complications
0.000 0.414 0.586
E13.1 With ketoacidosis
0.000 0.414 0.586
E13.0 With coma
0.000 0.414 0.586
E14.8 With unspecified complications
0.000 0.414 0.586
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.415 0.585
E07 Other disorders of thyroid
0.000 0.425 0.575
E13.3 With ophthalmic complications
0.000 0.440 0.560
E14.4 With neurological complications
0.000 0.443 0.557
E10.5 With peripheral circulatory complications
0.000 0.446 0.554
E14.1 With ketoacidosis
0.000 0.451 0.549
E06 Thyroiditis
0.000 0.452 0.548
E14.7 With multiple complications
0.000 0.471 0.529
E14.0 With coma
0.000 0.471 0.529
E12.9 Without complications
0.000 0.493 0.507
E12.8 With unspecified complications
0.000 0.493 0.507
E12.7 With multiple complications
0.000 0.493 0.507
E12.6 With other specified complications
0.000 0.493 0.507
E12.5 With peripheral circulatory complications
0.000 0.493 0.507
E12.4 With neurological complications
0.000 0.493 0.507
E12.3 With ophthalmic complications
0.000 0.493 0.507
E12.2 With renal complications
0.000 0.493 0.507
E12.1 With ketoacidosis
0.000 0.493 0.507
E12.0 With coma
0.000 0.493 0.507
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.495 0.504
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.495 0.504
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.495 0.504
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.495 0.504
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.495 0.504
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.495 0.504
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.495 0.504
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.495 0.504
E14.2 Withrenal complications
0.000 0.503 0.497
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.524 0.476
E45 Retarded development following protein-energy malnutrition
0.000 0.524 0.476
E43 Unspecified severe protein-energy malnutrition
0.000 0.524 0.476
E42 Marasmic kwashiorkor
0.000 0.524 0.476
E41 Nutritional marasmus
0.000 0.524 0.476
E40 Kwashiorkor
0.000 0.524 0.476
K90 Intestinal malabsorption
0.000 0.525 0.475
E14.5 With peripheral circulatory complications
0.000 0.531 0.469
E07.8 Other specified disorders of thyroid
0.000 0.546 0.454
E10.8 With unspecified complications
0.001 0.548 0.452
E46 Unspecified protein-energy malnutrition
0.000 0.564 0.436
E06.9 Thyroiditis, unspecified
0.000 0.573 0.427
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.581 0.418
E03 Other hypothyroidism
0.000 0.586 0.414
E07.1 Dyshormogenetic goitre
0.000 0.588 0.412
E07.0 Hypersecretion of calcitonin
0.000 0.588 0.412
E06.1 Subacute thyroiditis
0.000 0.591 0.409
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.601 0.399
E06.4 Drug-induced thyroiditis
0.000 0.607 0.393
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.607 0.393
E06.0 Acute thyroiditis
0.000 0.607 0.393
E06.5 Other chronic thyroiditis
0.000 0.611 0.389
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.385 0.615 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.654 0.346
E44.1 Mild protein-energy malnutrition
0.000 0.658 0.342
E44.0 Moderate protein-energy malnutrition
0.000 0.658 0.342
K90.3 Pancreatic steatorrhoea
0.000 0.659 0.341
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.659 0.341
K90.1 Tropical sprue
0.000 0.659 0.341
E83 Disorders of mineral metabolism
0.332 0.668 0.001
E50-E64 Other nutritional deficiencies
0.000 0.675 0.325
K90.9 Intestinal malabsorption, unspecified
0.000 0.681 0.319
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.689 0.311
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.692 0.308
E83.3 Disorders of phosphorus metabolism
0.306 0.694 0.000
K90.8 Other intestinal malabsorption
0.000 0.696 0.304
E03.5 Myxoedema coma
0.000 0.703 0.297
E03.4 Atrophy of thyroid (acquired)
0.000 0.703 0.297
E03.3 Postinfectious hypothyroidism
0.000 0.703 0.297
E03.1 Congenital hypothyroidism without goitre
0.000 0.705 0.295
E03.8 Other specified hypothyroidism
0.000 0.739 0.261
E83.9 Disorder of mineral metabolism, unspecified
0.248 0.751 0.000
E67 Other hyperalimentation
0.000 0.751 0.248
E68 Sequelae of hyperalimentation
0.000 0.751 0.248
E51 Thiamine deficiency
0.000 0.757 0.242
E83.8 Other disorders of mineral metabolism
0.238 0.762 0.001
E83.2 Disorders of zinc metabolism
0.238 0.762 0.001
E83.0 Disorders of copper metabolism
0.238 0.762 0.001
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.767 0.233
E50 Vitamin A deficiency
0.000 0.767 0.233
E60 Dietary zinc deficiency
0.000 0.767 0.233
E59 Dietary selenium deficiency
0.000 0.767 0.233
E54 Ascorbic acid deficiency
0.000 0.767 0.233
E52 Niacin deficiency [pellagra]
0.000 0.767 0.233
E56 Other vitamin deficiencies
0.000 0.782 0.218
E65 Localised adiposity
0.000 0.789 0.210
E63 Other nutritional deficiencies
0.000 0.790 0.209
E58 Dietary calcium deficiency
0.000 0.791 0.209
E61 Deficiency of other nutrient elements
0.000 0.802 0.198
E55 Vitamin D deficiency
0.000 0.807 0.193
E51.2 Wernicke's encephalopathy
0.000 0.816 0.183
E07.9 Disorder of thyroid, unspecified
0.000 0.817 0.182
E67.8 Other specified hyperalimentation
0.000 0.822 0.178
E67.3 Hypervitaminosis D
0.000 0.822 0.178
E67.2 Megavitamin-B6 syndrome
0.000 0.822 0.178
E67.1 Hypercarotenaemia
0.000 0.822 0.178
E67.0 Hypervitaminosis A
0.000 0.822 0.178
E53 Deficiency of other B group vitamins
0.000 0.822 0.178
E51.9 Thiamine deficiency, unspecified
0.000 0.826 0.174
E51.8 Other manifestations of thiamine deficiency
0.000 0.826 0.174
E51.1 Beriberi
0.000 0.826 0.174
E50.9 Vitamin A deficiency, unspecified
0.000 0.833 0.167
E50.8 Other manifestations of vitamin A deficiency
0.000 0.833 0.167
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.833 0.167
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.833 0.167
E50.5 Vitamin A deficiency with night blindness
0.000 0.833 0.167
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.833 0.167
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.833 0.167
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.833 0.167
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.833 0.167
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.833 0.167
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.833 0.167
E64.8 Sequelae of other nutritional deficiencies
0.000 0.833 0.167
E64.3 Sequelae of rickets
0.000 0.833 0.167
E64.2 Sequelae of vitamin C deficiency
0.000 0.833 0.167
E64.1 Sequelae of vitamin A deficiency
0.000 0.833 0.167
E64.0 Sequelae of protein-energy malnutrition
0.000 0.833 0.167
E11 Non-insulin-dependent diabetes mellitus
0.000 0.837 0.163
E83.4 Disorders of magnesium metabolism
0.160 0.840 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.843 0.156
E56.8 Deficiency of other vitamins
0.000 0.843 0.156
E56.0 Deficiency of vitamin E
0.000 0.843 0.156
E11.6 With other specified complications
0.000 0.847 0.153
E63.8 Other specified nutritional deficiencies
0.000 0.849 0.150
E63.1 Imbalance of constituents of food intake
0.000 0.849 0.150
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.849 0.150
E61.9 Deficiency of nutrient element, unspecified
0.000 0.858 0.142
E61.8 Deficiency of other specified nutrient elements
0.000 0.858 0.142
E61.7 Deficiency of multiple nutrient elements
0.000 0.858 0.142
E61.6 Vanadium deficiency
0.000 0.858 0.142
E61.5 Molybdenum deficiency
0.000 0.858 0.142
E61.4 Chromium deficiency
0.000 0.858 0.142
E61.3 Manganese deficiency
0.000 0.858 0.142
E61.0 Copper deficiency
0.000 0.858 0.142
E56.1 Deficiency of vitamin K
0.000 0.858 0.142
E55.0 Rickets, active
0.000 0.861 0.139
E53.9 Vitamin B deficiency, unspecified
0.000 0.862 0.138
E61.1 Iron deficiency
0.000 0.864 0.136
E53.1 Pyridoxine deficiency
0.000 0.872 0.128
E53.0 Riboflavin deficiency
0.000 0.872 0.128
E63.9 Nutritional deficiency, unspecified
0.000 0.873 0.127
E11.1 With ketoacidosis
0.000 0.875 0.125
E11.7 With multiple complications
0.000 0.883 0.117
E61.2 Magnesium deficiency
0.000 0.883 0.116
E06.3 Autoimmune thyroiditis
0.001 0.884 0.115
E14.9 Without complications
0.000 0.886 0.114
E11.8 With unspecified complications
0.000 0.894 0.106
E55.9 Vitamin D deficiency, unspecified
0.000 0.901 0.099
E11.0 With coma
0.000 0.901 0.099
E11.2 With renal complications
0.000 0.903 0.096
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.912 0.088
E11.5 With peripheral circulatory complications
0.000 0.922 0.078
C20 Malignant neoplasm of rectum
0.000 0.927 0.073
E20-E35 Disorders of other endocrine glands
0.000 0.931 0.069
C15-C26 Malignant neoplasms of digestive organs
0.000 0.932 0.068
E11.3 With ophthalmic complications
0.000 0.935 0.065
C15 Malignant neoplasm of oesophagus
0.000 0.937 0.063
C25 Malignant neoplasm of pancreas
0.000 0.940 0.060
I83 Varicose veins of lower extremities
0.059 0.941 0.000
C15.4 Middle third of oesophagus
0.000 0.941 0.059
E24 Cushing's syndrome
0.000 0.943 0.057
C17 Malignant neoplasm of small intestine
0.000 0.943 0.056
C15.5 Lower third of oesophagus
0.000 0.946 0.054
C17.0 Duodenum
0.000 0.946 0.054
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.949 0.051
E25 Adrenogenital disorders
0.000 0.949 0.051
C25.3 Pancreatic duct
0.000 0.949 0.051
C25.1 Body of pancreas
0.000 0.950 0.050
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.950 0.050
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.950 0.050
E32 Diseases of thymus
0.000 0.950 0.050
E30 Disorders of puberty, not elsewhere classified
0.000 0.950 0.050
E20 Hypoparathyroidism
0.000 0.951 0.049
E53.8 Deficiency of other specified B group vitamins
0.000 0.952 0.048
E04 Other non-toxic goitre
0.003 0.952 0.045
E31 Polyglandular dysfunction
0.000 0.953 0.047
C15.0 Cervical part of oesophagus
0.000 0.953 0.047
C25.8 Overlapping lesion of pancreas
0.000 0.954 0.046
C25.4 Endocrine pancreas
0.000 0.954 0.046
C24.0 Extrahepatic bile duct
0.000 0.954 0.046
E22 Hyperfunction of pituitary gland
0.000 0.954 0.046
E21.3 Hyperparathyroidism, unspecified
0.000 0.954 0.046
E24.2 Drug-induced Cushing's syndrome
0.000 0.954 0.045
C15.8 Overlapping lesion of oesophagus
0.000 0.955 0.045
C15.2 Abdominal part of oesophagus
0.000 0.955 0.045
E11.4 With neurological complications
0.000 0.955 0.045
C25.2 Tail of pancreas
0.000 0.955 0.045
E24.0 Pituitary-dependent Cushing's disease
0.000 0.956 0.044
E29 Testicular dysfunction
0.000 0.956 0.044
C15.1 Thoracic part of oesophagus
0.000 0.956 0.044
C25.9 Pancreas, unspecified
0.000 0.957 0.043
E24.8 Other Cushing's syndrome
0.000 0.957 0.043
C17.1 Jejunum
0.000 0.958 0.042
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.959 0.041
E24.3 Ectopic ACTH syndrome
0.000 0.959 0.041
E24.1 Nelson's syndrome
0.000 0.959 0.041
C15.3 Upper third of oesophagus
0.000 0.959 0.041
C17.8 Overlapping lesion of small intestine
0.000 0.959 0.041
C17.3 Meckel's diverticulum
0.000 0.959 0.041
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.040 0.960 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.960 0.040
E34 Other endocrine disorders
0.000 0.960 0.040
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.960 0.039
C25.7 Other parts of pancreas
0.000 0.961 0.038
I83.0 Varicose veins of lower extremities with ulcer
0.038 0.962 0.000
C15.9 Oesophagus, unspecified
0.000 0.962 0.038
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.963 0.037
E22.1 Hyperprolactinaemia
0.000 0.963 0.037
C24.8 Overlapping lesion of biliary tract
0.000 0.963 0.037
C24.9 Biliary tract, unspecified
0.000 0.963 0.037
E25.9 Adrenogenital disorder, unspecified
0.000 0.963 0.036
E25.8 Other adrenogenital disorders
0.000 0.963 0.036
E21.4 Other specified disorders of parathyroid gland
0.000 0.964 0.036
E30.9 Disorder of puberty, unspecified
0.000 0.964 0.036
E30.8 Other disorders of puberty
0.000 0.964 0.036
E30.1 Precocious puberty
0.000 0.964 0.036
E30.0 Delayed puberty
0.000 0.964 0.036
E32.9 Disease of thymus, unspecified
0.000 0.964 0.036
E32.8 Other diseases of thymus
0.000 0.964 0.036
E32.1 Abscess of thymus
0.000 0.964 0.036
E32.0 Persistent hyperplasia of thymus
0.000 0.964 0.036
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.964 0.036
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.964 0.036
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.964 0.036
E21.2 Other hyperparathyroidism
0.000 0.964 0.036
E28 Ovarian dysfunction
0.000 0.964 0.036
E11.9 Without complications
0.000 0.964 0.036
E20.8 Other hypoparathyroidism
0.000 0.964 0.035
E20.1 Pseudohypoparathyroidism
0.000 0.964 0.035
E20.0 Idiopathic hypoparathyroidism
0.000 0.964 0.035
E03.9 Hypothyroidism, unspecified
0.000 0.965 0.035
C18.9 Colon, unspecified
0.000 0.965 0.035
E20.9 Hypoparathyroidism, unspecified
0.000 0.965 0.034
E04.8 Other specified non-toxic goitre
0.002 0.966 0.032
E31.9 Polyglandular dysfunction, unspecified
0.000 0.966 0.034
E31.8 Other polyglandular dysfunction
0.000 0.966 0.034
E31.1 Polyglandular hyperfunction
0.000 0.966 0.034
E26 Hyperaldosteronism
0.000 0.966 0.033
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.966 0.034
C25.0 Head of pancreas
0.000 0.966 0.034
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.966 0.034
K14.8 Other diseases of tongue
0.000 0.966 0.034
C17.9 Small intestine, unspecified
0.000 0.967 0.033
E22.8 Other hyperfunction of pituitary gland
0.000 0.967 0.033
C18 Malignant neoplasm of colon
0.000 0.967 0.033
E29.9 Testicular dysfunction, unspecified
0.000 0.968 0.032
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.968 0.032
E29.8 Other testicular dysfunction
0.000 0.968 0.032
E29.0 Testicular hyperfunction
0.000 0.968 0.032
E31.0 Autoimmune polyglandular failure
0.000 0.968 0.031
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.969 0.031
E34.9 Endocrine disorder, unspecified
0.000 0.970 0.030
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.971 0.029
E34.3 Short stature, not elsewhere classified
0.000 0.971 0.029
E34.5 Androgen resistance syndrome
0.000 0.971 0.029
E34.4 Constitutional tall stature
0.000 0.971 0.029
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.971 0.029
E34.1 Other hypersecretion of intestinal hormones
0.000 0.971 0.029
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
C23 Malignant neoplasm of gallbladder
0.000 0.972 0.028
C18.1 Appendix
0.000 0.972 0.028
E22.0 Acromegaly and pituitary gigantism
0.000 0.973 0.026
E28.9 Ovarian dysfunction, unspecified
0.000 0.974 0.026
E28.8 Other ovarian dysfunction
0.000 0.974 0.026
E28.1 Androgen excess
0.000 0.974 0.026
E28.0 Oestrogen excess
0.000 0.974 0.026
E29.1 Testicular hypofunction
0.000 0.974 0.025
C22.9 Liver, unspecified
0.000 0.975 0.025
C17.2 Ileum
0.000 0.975 0.025
C18.8 Overlapping lesion of colon
0.000 0.975 0.025
E26.8 Other hyperaldosteronism
0.000 0.975 0.024
E26.1 Secondary hyperaldosteronism
0.000 0.975 0.024
C22.7 Other specified carcinomas of liver
0.000 0.975 0.024
C22.4 Other sarcomas of liver
0.000 0.975 0.024
C22.3 Angiosarcoma of liver
0.000 0.975 0.024
C22.2 Hepatoblastoma
0.000 0.975 0.024
E04.0 Non-toxic diffuse goitre
0.002 0.976 0.022
C26.8 Overlapping lesion of digestive system
0.000 0.976 0.024
C26.1 Spleen
0.000 0.976 0.024
C21 Malignant neoplasm of anus and anal canal
0.000 0.976 0.024
E34.8 Other specified endocrine disorders
0.000 0.976 0.023
E23 Hypofunction and other disorders of pituitary gland
0.000 0.976 0.024
C22.1 Intrahepatic bile duct carcinoma
0.000 0.977 0.023
E34.0 Carcinoid syndrome
0.000 0.977 0.023
E26.9 Hyperaldosteronism, unspecified
0.000 0.978 0.022
C18.2 Ascending colon
0.000 0.978 0.022
E28.3 Primary ovarian failure
0.000 0.978 0.021
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.020
E28.2 Polycystic ovarian syndrome
0.000 0.981 0.019
E83.5 Disorders of calcium metabolism
0.019 0.981 0.000
C26.0 Intestinal tract, part unspecified
0.000 0.981 0.019
C24.1 Ampulla of Vater
0.001 0.981 0.018
C18.6 Descending colon
0.000 0.981 0.018
C18.4 Transverse colon
0.000 0.982 0.018
E23.7 Disorder of pituitary gland, unspecified
0.000 0.982 0.018
C26.9 Ill-defined sites within the digestive system
0.000 0.982 0.018
C21.2 Cloacogenic zone
0.000 0.983 0.017
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.983 0.017
E23.1 Drug-induced hypopituitarism
0.000 0.983 0.017
E66 Obesity
0.000 0.983 0.017
E27 Other disorders of adrenal gland
0.000 0.983 0.017
E21.0 Primary hyperparathyroidism
0.000 0.983 0.017
E70-E90 Metabolic disorders
0.007 0.983 0.009
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.984 0.015
H40.2 Primary angle-closure glaucoma
0.015 0.985 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.015
K93.1 Megacolon in Chagas' disease
0.000 0.985 0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.985 0.015
R31 Unspecified haematuria
0.015 0.985 0.000
Z71.8 Other specified counselling
0.014 0.986 0.000
K14 Diseases of tongue
0.000 0.986 0.014
E23.2 Diabetes insipidus
0.000 0.986 0.014
K14.6 Glossodynia
0.000 0.986 0.013
M45.X9 Ankylosing spondylitis (Site unspecified)
0.013 0.987 0.000
E23.6 Other disorders of pituitary gland
0.000 0.987 0.013
E26.0 Primary hyperaldosteronism
0.001 0.987 0.012
E27.1 Primary adrenocortical insufficiency
0.000 0.987 0.013
C18.3 Hepatic flexure
0.000 0.987 0.013
C18.7 Sigmoid colon
0.000 0.987 0.013
I83.1 Varicose veins of lower extremities with inflammation
0.012 0.987 0.000
E66.1 Drug-induced obesity
0.000 0.987 0.012
E27.5 Adrenomedullary hyperfunction
0.000 0.988 0.012
E27.0 Other adrenocortical overactivity
0.000 0.988 0.012
E77 Disorders of glycoprotein metabolism
0.005 0.988 0.007
E76 Disorders of glycosaminoglycan metabolism
0.005 0.988 0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.005 0.988 0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.005 0.988 0.007
E04.9 Non-toxic goitre, unspecified
0.001 0.988 0.011
E70 Disorders of aromatic amino-acid metabolism
0.006 0.988 0.006
E72 Other disorders of amino-acid metabolism
0.006 0.988 0.006
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.005 0.988 0.007
E79 Disorders of purine and pyrimidine metabolism
0.006 0.988 0.006
E84 Cystic fibrosis
0.006 0.988 0.006
E73 Lactose intolerance
0.004 0.988 0.007
E74 Other disorders of carbohydrate metabolism
0.005 0.989 0.007
C21.1 Anal canal
0.000 0.989 0.011
K14.1 Geographic tongue
0.000 0.989 0.011
K14.3 Hypertrophy of tongue papillae
0.000 0.989 0.011
E27.9 Disorder of adrenal gland, unspecified
0.000 0.989 0.011
E85 Amyloidosis
0.005 0.989 0.006
K14.5 Plicated tongue
0.000 0.989 0.010
K14.4 Atrophy of tongue papillae
0.000 0.989 0.010
C21.0 Anus, unspecified
0.000 0.990 0.010
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.990 0.010
C22.0 Liver cell carcinoma
0.000 0.990 0.009
E27.2 Addisonian crisis
0.000 0.990 0.009
C18.5 Splenic flexure
0.000 0.991 0.009
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.991 0.009
K14.2 Median rhomboid glossitis
0.000 0.991 0.009
E88 Other metabolic disorders
0.003 0.991 0.006
C16 Malignant neoplasm of stomach
0.000 0.991 0.009
E71.3 Disorders of fatty-acid metabolism
0.004 0.991 0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.004 0.991 0.005
E71.1 Other disorders of branched-chain amino-acid metabolism
0.004 0.991 0.005
E71.0 Maple-syrup-urine disease
0.004 0.991 0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.004 0.991 0.005
E76.8 Other disorders of glucosaminoglycan metabolism
0.004 0.991 0.005
E76.3 Mucopolysaccharidosis, unspecified
0.004 0.991 0.005
E76.2 Other mucopolysaccharidoses
0.004 0.991 0.005
E76.1 Mucopolysaccharidosis, type II
0.004 0.991 0.005
E76.0 Mucopolysaccharidosis, type I
0.004 0.991 0.005
E77.9 Disorder of glycoprotein metabolism, unspecified
0.004 0.991 0.005
E77.8 Other disorders of glycoprotein metabolism
0.004 0.991 0.005
E77.1 Defects in glycoprotein degradation
0.004 0.991 0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.004 0.991 0.005
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.991 0.009
H66.3 Other chronic suppurative otitis media
0.009 0.991 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.006 0.991 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.004 0.991 0.005
E70.8 Other disorders of aromatic amino-acid metabolism
0.004 0.991 0.005
E70.2 Disorders of tyrosine metabolism
0.004 0.991 0.005
E70.1 Other hyperphenylalaninaemias
0.004 0.991 0.005
E70.0 Classical phenylketonuria
0.004 0.991 0.005
E72.9 Disorder of amino-acid metabolism, unspecified
0.004 0.991 0.005
E72.8 Other specified disorders of amino-acid metabolism
0.004 0.991 0.005
E72.5 Disorders of glycine metabolism
0.004 0.991 0.005
E72.4 Disorders of ornithine metabolism
0.004 0.991 0.005
E72.3 Disorders of lysine and hydroxylysine metabolism
0.004 0.991 0.005
E72.2 Disorders of urea cycle metabolism
0.004 0.991 0.005
E75.6 Lipid storage disorder, unspecified
0.004 0.991 0.005
E75.4 Neuronal ceroid lipofuscinosis
0.004 0.991 0.005
E75.3 Sphingolipidosis, unspecified
0.004 0.991 0.005
E75.1 Other gangliosidosis
0.004 0.991 0.005
E75.0 GM2 gangliosidosis
0.004 0.991 0.005
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.004 0.991 0.005
E79.8 Other disorders of purine and pyrimidine metabolism
0.004 0.991 0.005
E79.1 Lesch-Nyhan syndrome
0.004 0.991 0.005
E72.0 Disorders of amino-acid transport
0.004 0.991 0.005
E84.8 Cystic fibrosis with other manifestations
0.004 0.991 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.004 0.991 0.004
E70.3 Albinism
0.004 0.991 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.004 0.991 0.004
E75.2 Other sphingolipidosis
0.004 0.991 0.005
E75.5 Other lipid storage disorders
0.003 0.991 0.005
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.991 0.009
E84.0 Cystic fibrosis with pulmonary manifestations
0.004 0.991 0.004
H40.5 Glaucoma secondary to other eye disorders
0.009 0.991 0.000
E73.8 Other lactose intolerance
0.003 0.991 0.005
E73.1 Secondary lactase deficiency
0.003 0.991 0.005
E73.0 Congenital lactase deficiency
0.003 0.991 0.005
K14.0 Glossitis
0.000 0.991 0.008
E74.9 Disorder of carbohydrate metabolism, unspecified
0.004 0.992 0.005
E74.8 Other specified disorders of carbohydrate metabolism
0.004 0.992 0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.004 0.992 0.005
E74.2 Disorders of galactose metabolism
0.004 0.992 0.005
E74.1 Disorders of fructose metabolism
0.004 0.992 0.005
E74.0 Glycogen storage disease
0.004 0.992 0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.005 0.992 0.004
E84.9 Cystic fibrosis, unspecified
0.005 0.992 0.004
E78.5 Hyperlipidaemia, unspecified
0.000 0.992 0.008
E23.0 Hypopituitarism
0.000 0.992 0.008
E85.8 Other amyloidosis
0.004 0.992 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.004 0.992 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.004 0.992 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.004 0.992 0.004
E66.0 Obesity due to excess calories
0.001 0.992 0.007
C18.0 Caecum
0.000 0.992 0.008
E27.8 Other specified disorders of adrenal gland
0.000 0.992 0.008
E73.9 Lactose intolerance, unspecified
0.002 0.992 0.006
E74.3 Other disorders of intestinal carbohydrate absorption
0.003 0.992 0.004
E78.2 Mixed hyperlipidaemia
0.000 0.992 0.008
E85.3 Secondary systemic amyloidosis
0.003 0.992 0.004
E78.1 Pure hyperglyceridaemia
0.000 0.992 0.008
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.992 0.008
E78.6 Lipoprotein deficiency
0.000 0.992 0.007
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.993 0.007
E88.9 Metabolic disorder, unspecified
0.002 0.993 0.006
E85.4 Organ-limited amyloidosis
0.003 0.993 0.004
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.993 0.007
H40 Glaucoma
0.007 0.993 0.000
E85.9 Amyloidosis, unspecified
0.005 0.993 0.003
I97.1 Other functional disturbances following cardiac surgery
0.000 0.993 0.007
E88.1 Lipodystrophy, not elsewhere classified
0.002 0.993 0.005
E80.1 Porphyria cutanea tarda
0.005 0.993 0.002
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.993 0.007
E88.2 Lipomatosis, not elsewhere classified
0.002 0.993 0.005
E80.7 Disorder of bilirubin metabolism, unspecified
0.004 0.993 0.002
E80.5 Crigler-Najjar syndrome
0.004 0.993 0.002
E80.3 Defects of catalase and peroxydase
0.004 0.993 0.002
E80.0 Hereditary erythropoietic porphyria
0.004 0.993 0.002
C16.5 Lesser curvature of stomach, unspecified
0.000 0.993 0.007
E80.6 Other disorders of bilirubin metabolism
0.005 0.993 0.002
W22 Striking against or struck by other objects
0.000 0.993 0.007
C16.8 Overlapping lesion of stomach
0.000 0.993 0.006
E88.8 Other specified metabolic disorders
0.003 0.993 0.004
E78.3 Hyperchylomicronaemia
0.000 0.994 0.006
E04.1 Non-toxic single thyroid nodule
0.003 0.994 0.004
S20.8 Superficial injuries of other and unspecified parts of thorax
0.000 0.994 0.006
E88.3 Tumour lysis syndrome
0.003 0.994 0.003
W22.3 Sports and athletics area
0.000 0.994 0.006
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.004 0.994 0.002
E80.2 Other porphyria
0.004 0.994 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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