TreeWAS – Variant ID: rs3749981

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.999	0.001	0.000
E14.9 Without complications	0.998	0.002	0.000
E10.1 With ketoacidosis	0.998	0.002	0.000
J00-J06 Acute upper respiratory infections	0.997	0.003	0.000
J33.9 Nasal polyp, unspecified	0.995	0.005	0.000
E00-E07 Disorders of thyroid gland	0.994	0.006	0.000
J33 Nasal polyp	0.994	0.006	0.000
J30-J39 Other diseases of upper respiratory tract	0.991	0.009	0.000
E03 Other hypothyroidism	0.990	0.010	0.000
E11 Non-insulin-dependent diabetes mellitus	0.989	0.011	0.000
E10.4 With neurological complications	0.989	0.011	0.000
E03.9 Hypothyroidism, unspecified	0.988	0.012	0.000
E11.9 Without complications	0.982	0.018	0.000
J02 Acute pharyngitis	0.980	0.020	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.978	0.022	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.978	0.022	0.000
J40-J47 Chronic lower respiratory diseases	0.978	0.022	0.000
J45 Asthma	0.976	0.024	0.000
J45.9 Asthma, unspecified	0.975	0.025	0.000
Chapter VII Diseases of the eye and adnexa	0.974	0.026	0.000
H36.0 Diabetic retinopathy	0.971	0.029	0.000
J02.9 Acute pharyngitis, unspecified	0.969	0.031	0.000
H36 Retinal disorders in diseases classified elsewhere	0.969	0.031	0.000
H30-H36 Disorders of choroid and retina	0.967	0.033	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.966	0.034	0.000
E16 Other disorders of pancreatic internal secretion	0.962	0.038	0.000
E16.2 Hypoglycaemia, unspecified	0.949	0.051	0.000
E14.3 With ophthalmic complications	0.944	0.056	0.000
M31 Other necrotising vasculopathies	0.937	0.063	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.933	0.067	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.925	0.075	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.925	0.075	0.000
J00 Acute nasopharyngitis [common cold]	0.924	0.076	0.000
M65-M68 Disorders of synovium and tendon	0.921	0.079	0.000
E10.5 With peripheral circulatory complications	0.921	0.079	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.920	0.080	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.919	0.081	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.919	0.081	0.000
M86-M90 Other osteopathies	0.918	0.081	0.000
M06.3 Rheumatoid nodule	0.917	0.083	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.902	0.098	0.000
K90.0 Coeliac disease	0.000	0.102	0.898
J33.0 Polyp of nasal cavity	0.896	0.104	0.000
E10.2 With renal complications	0.895	0.105	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.894	0.106	0.000
M80-M85 Disorders of bone density and structure	0.885	0.115	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.881	0.119	0.000
E14.6 With other specified complications	0.878	0.122	0.000
E10.0 With coma	0.877	0.123	0.000
T92 Sequelae of injuries of upper limb	0.875	0.125	0.000
J06.9 Acute upper respiratory infection, unspecified	0.874	0.126	0.000
E06 Thyroiditis	0.869	0.131	0.000
M24 Other specific joint derangements	0.866	0.134	0.000
M30 Polyarteritis nodosa and related conditions	0.863	0.137	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.863	0.137	0.000
M14 Arthropathies in other diseases classified elsewhere	0.861	0.139	0.000
H20 Iridocyclitis	0.855	0.145	0.000
T92.1 Sequelae of fracture of arm	0.847	0.153	0.000
M06.4 Inflammatory polyarthropathy	0.846	0.154	0.000
E50-E64 Other nutritional deficiencies	0.834	0.166	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.831	0.169	0.000
E07 Other disorders of thyroid	0.829	0.171	0.000
M06.34 Rheumatoid nodule (Hand)	0.829	0.171	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.824	0.176	0.000
E10.6 With other specified complications	0.824	0.176	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.823	0.177	0.000
S90-S99 Injuries to the ankle and foot	0.819	0.181	0.000
M31.3 Wegener's granulomatosis	0.816	0.184	0.000
M31.6 Other giant cell arteritis	0.813	0.187	0.000
Chapter XX External causes of morbidity and mortality	0.809	0.191	0.000
M35.7 Hypermobility syndrome	0.809	0.191	0.000
M66 Spontaneous rupture of synovium and tendon	0.808	0.192	0.000
M65 Synovitis and tenosynovitis	0.808	0.192	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.806	0.194	0.000
T91 Sequelae of injuries of neck and trunk	0.805	0.195	0.000
M89 Other disorders of bone	0.804	0.196	0.000
Q80-Q89 Other congenital malformations	0.801	0.199	0.000
E11.6 With other specified complications	0.801	0.199	0.000
M60-M63 Disorders of muscles	0.799	0.201	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.798	0.202	0.000
M86 Osteomyelitis	0.796	0.204	0.000
M35.1 Other overlap syndromes	0.795	0.205	0.000
M24.5 Contracture of joint	0.794	0.206	0.000
S00-S09 Injuries to the head	0.787	0.213	0.000
J42 Unspecified chronic bronchitis	0.786	0.214	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.782	0.218	0.000
J01 Acute sinusitis	0.781	0.219	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.780	0.220	0.000
H20.0 Acute and subacute iridocyclitis	0.777	0.223	0.000
E10.8 With unspecified complications	0.776	0.224	0.000
E11.3 With ophthalmic complications	0.774	0.226	0.000
M22 Disorders of patella	0.772	0.228	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.769	0.231	0.000
M00-M03 Infectious arthropathies	0.766	0.234	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.764	0.236	0.000
M80 Osteoporosis with pathological fracture	0.763	0.237	0.000
M14.6 Neuropathic arthropathy	0.761	0.239	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.760	0.240	0.000
H30 Chorioretinal inflammation	0.758	0.242	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.758	0.242	0.000
E06.3 Autoimmune thyroiditis	0.758	0.242	0.000
J35 Chronic diseases of tonsils and adenoids	0.757	0.243	0.000
L08 Other local infections of skin and subcutaneous tissue	0.757	0.243	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.755	0.245	0.000
J60-J70 Lung diseases due to external agents	0.753	0.247	0.000
H21 Other disorders of iris and ciliary body	0.753	0.247	0.000
M87 Osteonecrosis	0.747	0.253	0.000
M91-M94 Chondropathies	0.743	0.257	0.000
T79-T79 Certain early complications of trauma	0.739	0.261	0.000
S09 Other and unspecified injuries of head	0.738	0.262	0.000
J45.0 Predominantly allergic asthma	0.736	0.264	0.000
H31 Other disorders of choroid	0.734	0.266	0.000
M84 Disorders of continuity of bone	0.731	0.269	0.000
Chapter VI Diseases of the nervous system	0.729	0.271	0.000
E11.4 With neurological complications	0.729	0.271	0.000
E11.0 With coma	0.728	0.272	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.727	0.273	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.727	0.273	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.726	0.273	0.000
E11.2 With renal complications	0.726	0.274	0.000
M33 Dermatopolymyositis	0.725	0.275	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.725	0.275	0.000
H17 Corneal scars and opacities	0.723	0.277	0.000
E61 Deficiency of other nutrient elements	0.723	0.277	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.723	0.277	0.000
M24.54 Contracture of joint (Hand)	0.723	0.277	0.000
W00-W19 Falls	0.721	0.279	0.000
M32 Systemic lupus erythematosus	0.719	0.281	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.719	0.281	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.719	0.281	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.718	0.282	0.000
E11.8 With unspecified complications	0.718	0.282	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E14.8 With unspecified complications	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.5 With peripheral circulatory complications	0.717	0.283	0.000
E14.4 With neurological complications	0.717	0.283	0.000
E14.2 Withrenal complications	0.717	0.283	0.000
E14.1 With ketoacidosis	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
Q78 Other osteochondrodysplasias	0.717	0.283	0.000
M05.8 Other seropositive rheumatoid arthritis	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.1 Rheumatoid lung disease	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.717	0.283	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.717	0.283	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M35.2 Behcet's disease	0.717	0.283	0.000
S10-S19 Injuries to the neck	0.717	0.283	0.000
J46 Status asthmaticus	0.716	0.284	0.000
H15 Disorders of sclera	0.716	0.284	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.716	0.284	0.000
M22.2 Patellofemoral disorders	0.715	0.285	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.715	0.285	0.000
M25 Other joint disorders, not elsewhere classified	0.714	0.286	0.000
S09.9 Unspecified injury of head	0.714	0.286	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.713	0.287	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.712	0.288	0.000
E00 Congenital iodine-deficiency syndrome	0.712	0.288	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.712	0.288	0.000
J33.1 Polypoid sinus degeneration	0.712	0.288	0.000
E07.9 Disorder of thyroid, unspecified	0.712	0.288	0.000
E03.5 Myxoedema coma	0.709	0.290	0.000
E03.4 Atrophy of thyroid (acquired)	0.709	0.290	0.000
E03.3 Postinfectious hypothyroidism	0.709	0.290	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.709	0.290	0.000
E03.1 Congenital hypothyroidism without goitre	0.709	0.290	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.709	0.290	0.000
S80-S89 Injuries to the knee and lower leg	0.709	0.291	0.000
E11.7 With multiple complications	0.709	0.291	0.000
T00-T07 Injuries involving multiple body regions	0.707	0.293	0.000
G63.2 Diabetic polyneuropathy	0.705	0.295	0.000
H52 Disorders of refraction and accommodation	0.705	0.295	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.703	0.297	0.000
J02.0 Streptococcal pharyngitis	0.703	0.297	0.000
H55-H59 Other disorders of eye and adnexa	0.702	0.297	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.701	0.299	0.000
T91.3 Sequelae of injury of spinal cord	0.701	0.299	0.000
E15 Nondiabetic hypoglycaemic coma	0.701	0.299	0.000
J41 Simple and mucopurulent chronic bronchitis	0.701	0.299	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.701	0.299	0.000
Q24 Other congenital malformations of heart	0.701	0.299	0.000
J45.8 Mixed asthma	0.700	0.300	0.000
J45.1 Nonallergic asthma	0.700	0.300	0.000
M86.9 Osteomyelitis, unspecified	0.699	0.300	0.000
H53-H54 Visual disturbances and blindness	0.698	0.302	0.000
S02 Fracture of skull and facial bones	0.697	0.303	0.000
E13 Other specified diabetes mellitus	0.697	0.303	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.695	0.305	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.694	0.305	0.000
S82 Fracture of lower leg, including ankle	0.694	0.306	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.694	0.306	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.693	0.306	0.000
M66.0 Rupture of popliteal cyst	0.693	0.307	0.000
S92 Fracture of foot, except ankle	0.692	0.308	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.692	0.308	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.691	0.309	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.691	0.309	0.000
M89.0 Algoneurodystrophy	0.691	0.309	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.690	0.310	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.690	0.310	0.000
E16.4 Abnormal secretion of gastrin	0.690	0.310	0.000
E16.3 Increased secretion of glucagon	0.690	0.310	0.000
E16.1 Other hypoglycaemia	0.690	0.310	0.000
J33.8 Other polyp of sinus	0.689	0.311	0.000
M30.0 Polyarteritis nodosa	0.687	0.312	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.686	0.314	0.000
M24.6 Ankylosis of joint	0.686	0.314	0.000
T66-T78 Other and unspecified effects of external causes	0.684	0.316	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.682	0.318	0.000
S99 Other and unspecified injuries of ankle and foot	0.682	0.318	0.000
S70-S79 Injuries to the hip and thigh	0.681	0.319	0.000
M82 Osteoporosis in diseases classified elsewhere	0.680	0.320	0.000
M11 Other crystal arthropathies	0.678	0.322	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.678	0.322	0.000
H50 Other strabismus	0.676	0.324	0.000
H34 Retinal vascular occlusions	0.672	0.328	0.000
M31.9 Necrotising vasculopathy, unspecified	0.672	0.328	0.000
M31.8 Other specified necrotising vasculopathies	0.672	0.328	0.000
M31.7 Microscopic polyangiitis	0.672	0.328	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.672	0.328	0.000
M31.2 Lethal midline granuloma	0.672	0.328	0.000
M31.1 Thrombotic microangiopathy	0.672	0.328	0.000
M31.0 Hypersensitivity angiitis	0.672	0.328	0.000
E06.9 Thyroiditis, unspecified	0.671	0.329	0.000
S50-S59 Injuries to the elbow and forearm	0.671	0.329	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.671	0.329	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.670	0.330	0.000
H20.9 Iridocyclitis, unspecified	0.669	0.331	0.000
Q35-Q37 Cleft lip and cleft palate	0.669	0.331	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.669	0.331	0.000
T91.1 Sequelae of fracture of spine	0.667	0.333	0.000
V40-V49 Car occupant injured in transport accident	0.666	0.334	0.000
M85 Other disorders of bone density and structure	0.665	0.335	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.663	0.337	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.663	0.337	0.000
J06.0 Acute laryngopharyngitis	0.663	0.337	0.000
M24.2 Disorder of ligament	0.662	0.338	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.661	0.339	0.000
T33-T35 Frostbite	0.660	0.340	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.660	0.340	0.000
J38.6 Stenosis of larynx	0.660	0.340	0.000
H52.3 Anisometropia and aniseikonia	0.659	0.341	0.000
J86 Pyothorax	0.659	0.341	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.658	0.342	0.000
M06.38 Rheumatoid nodule (Other)	0.658	0.342	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.658	0.342	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.658	0.342	0.000
M06.33 Rheumatoid nodule (Forearm)	0.658	0.342	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.658	0.342	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.658	0.342	0.000
M65.1 Other infective (teno)synovitis	0.657	0.343	0.000
Q85 Phakomatoses, not elsewhere classified	0.655	0.345	0.000
Y84.2 Radiological procedure and radiotherapy	0.654	0.346	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.654	0.346	0.000
G62 Other polyneuropathies	0.654	0.346	0.000
H20.8 Other iridocyclitis	0.653	0.346	0.000
M87.2 Osteonecrosis due to previous trauma	0.653	0.347	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.651	0.349	0.000
S82.8 Fractures of other parts of lower leg	0.649	0.351	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.648	0.352	0.000
M24.7 Protrusio acetabuli	0.648	0.352	0.000
J40 Bronchitis, not specified as acute or chronic	0.648	0.352	0.000
L04 Acute lymphadenitis	0.647	0.353	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.647	0.353	0.000
M84.0 Malunion of fracture	0.646	0.354	0.000
M40-M43 Deforming dorsopathies	0.646	0.354	0.000
L20-L30 Dermatitis and eczema	0.646	0.354	0.000
Q66 Congenital deformities of feet	0.645	0.355	0.000
W13 Fall from, out of or through building or structure	0.645	0.355	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.644	0.356	0.000
E40-E46 Malnutrition	0.643	0.357	0.000
E61.1 Iron deficiency	0.643	0.357	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.643	0.357	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.641	0.358	0.000
T95 Sequelae of burns, corrosions and frostbite	0.641	0.359	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.641	0.359	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.641	0.359	0.000
X50-X57 Overexertion, travel and privation	0.640	0.360	0.000
M66.3 Spontaneous rupture of flexor tendons	0.640	0.360	0.000
S02.4 Fracture of malar and maxillary bones	0.640	0.360	0.000
W07 Fall involving chair	0.639	0.361	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.639	0.361	0.000
M62 Other disorders of muscle	0.638	0.362	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.637	0.363	0.000
Q78.0 Osteogenesis imperfecta	0.635	0.365	0.000
M83 Adult osteomalacia	0.635	0.365	0.000
W50-W64 Exposure to animate mechanical forces	0.634	0.366	0.000
E03.8 Other specified hypothyroidism	0.633	0.367	0.000
T98 Sequelae of other and unspecified effects of external causes	0.632	0.367	0.000
M24.51 Contracture of joint (Shoulder region)	0.632	0.368	0.000
S40-S49 Injuries to the shoulder and upper arm	0.632	0.368	0.000
J04 Acute laryngitis and tracheitis	0.631	0.369	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.630	0.370	0.000
M06.0 Seronegative rheumatoid arthritis	0.628	0.372	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.627	0.373	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.627	0.373	0.000
M22.9 Disorder of patella, unspecified	0.627	0.373	0.000
Chapter XXII Codes for special purposes	0.626	0.374	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.626	0.374	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.626	0.374	0.000
J01.9 Acute sinusitis, unspecified	0.626	0.374	0.000
T63 Toxic effect of contact with venomous animals	0.625	0.375	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.625	0.375	0.000
J35.0 Chronic tonsillitis	0.625	0.375	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.624	0.376	0.000
M67 Other disorders of synovium and tendon	0.624	0.376	0.000
J38.5 Laryngeal spasm	0.624	0.376	0.000
E06.5 Other chronic thyroiditis	0.623	0.377	0.000
E06.4 Drug-induced thyroiditis	0.623	0.377	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.623	0.377	0.000
E06.1 Subacute thyroiditis	0.623	0.377	0.000
E06.0 Acute thyroiditis	0.623	0.377	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.622	0.377	0.000
M24.9 Joint derangement, unspecified	0.621	0.379	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.621	0.379	0.000
M65.8 Other synovitis and tenosynovitis	0.620	0.380	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.619	0.381	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.619	0.381	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.619	0.381	0.000
M30.2 Juvenile polyarteritis	0.619	0.381	0.000
H43-H45 Disorders of vitreous body and globe	0.618	0.382	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.617	0.383	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.617	0.383	0.000
M14.4 Arthropathy in amyloidosis	0.617	0.383	0.000
M14.3 Lipoid dermatoarthritis	0.617	0.383	0.000
M14.2 Diabetic arthropathy	0.617	0.383	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.617	0.383	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.617	0.383	0.000
Q76 Congenital malformations of spine and bony thorax	0.617	0.383	0.000
V98-V99 Other and unspecified transport accidents	0.617	0.383	0.000
J38.2 Nodules of vocal cords	0.614	0.386	0.000
M89.3 Hypertrophy of bone	0.614	0.386	0.000
Q28 Other congenital malformations of circulatory system	0.614	0.386	0.000
H20.2 Lens-induced iridocyclitis	0.613	0.387	0.000
H20.1 Chronic iridocyclitis	0.613	0.387	0.000
G62.8 Other specified polyneuropathies	0.612	0.388	0.000
Q82 Other congenital malformations of skin	0.611	0.388	0.000
M34 Systemic sclerosis	0.611	0.389	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.611	0.389	0.000
Q50-Q56 Congenital malformations of genital organs	0.610	0.390	0.000
H16 Keratitis	0.610	0.390	0.000
H52.1 Myopia	0.610	0.390	0.000
Q89 Other congenital malformations, not elsewhere classified	0.610	0.390	0.000
E55 Vitamin D deficiency	0.609	0.391	0.000
Q24.8 Other specified congenital malformations of heart	0.609	0.391	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.609	0.391	0.000
T56 Toxic effect of metals	0.609	0.391	0.000
H30.9 Chorioretinal inflammation, unspecified	0.608	0.392	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.608	0.392	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.606	0.394	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.606	0.394	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.606	0.394	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.606	0.394	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.606	0.394	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.606	0.394	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.606	0.394	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.606	0.394	0.000
S90 Superficial injury of ankle and foot	0.606	0.394	0.000
T59 Toxic effect of other gases, fumes and vapours	0.606	0.394	0.000
J39 Other diseases of upper respiratory tract	0.606	0.394	0.000
S82.4 Fracture of fibula alone	0.605	0.395	0.000
M89.5 Osteolysis	0.605	0.395	0.000
S70 Superficial injury of hip and thigh	0.605	0.395	0.000
M94 Other disorders of cartilage	0.605	0.395	0.000
J38.7 Other diseases of larynx	0.605	0.395	0.000
Q83 Congenital malformations of breast	0.604	0.396	0.000
J31.2 Chronic pharyngitis	0.604	0.396	0.000
J35.1 Hypertrophy of tonsils	0.602	0.398	0.000
Y00-Y09 Assault	0.602	0.398	0.000
V80-V89 Other land transport accidents	0.600	0.399	0.000
M25.9 Joint disorder, unspecified	0.600	0.400	0.000
L05 Pilonidal cyst	0.600	0.400	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.600	0.400	0.000
S82.1 Fracture of upper end of tibia	0.599	0.401	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.599	0.401	0.000
Q27 Other congenital malformations of peripheral vascular system	0.599	0.401	0.000
M00 Pyogenic arthritis	0.598	0.401	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.598	0.402	0.000
E63 Other nutritional deficiencies	0.598	0.402	0.000
E56 Other vitamin deficiencies	0.598	0.402	0.000
E51 Thiamine deficiency	0.598	0.402	0.000
E50 Vitamin A deficiency	0.598	0.402	0.000
E60 Dietary zinc deficiency	0.598	0.402	0.000
E59 Dietary selenium deficiency	0.598	0.402	0.000
E58 Dietary calcium deficiency	0.598	0.402	0.000
E54 Ascorbic acid deficiency	0.598	0.402	0.000
E52 Niacin deficiency [pellagra]	0.598	0.402	0.000
M60 Myositis	0.598	0.402	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.596	0.404	0.000
Q75 Other congenital malformations of skull and face bones	0.596	0.404	0.000
Q74 Other congenital malformations of limb(s)	0.596	0.404	0.000
Q73 Reduction defects of unspecified limb	0.596	0.404	0.000
Q72 Reduction defects of lower limb	0.596	0.404	0.000
Q71 Reduction defects of upper limb	0.596	0.404	0.000
Q70 Syndactyly	0.596	0.404	0.000
Q69 Polydactyly	0.596	0.404	0.000
Q68 Other congenital musculoskeletal deformities	0.596	0.404	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.596	0.404	0.000
T58 Toxic effect of carbon monoxide	0.595	0.405	0.000
M07 Psoriatic and enteropathic arthropathies	0.595	0.405	0.000
E07.8 Other specified disorders of thyroid	0.595	0.405	0.000
E07.1 Dyshormogenetic goitre	0.595	0.405	0.000
E07.0 Hypersecretion of calcitonin	0.595	0.405	0.000
S02.2 Fracture of nasal bones	0.594	0.406	0.000
Q65 Congenital deformities of hip	0.593	0.407	0.000
M25.0 Haemarthrosis	0.593	0.407	0.000
J37 Chronic laryngitis and laryngotracheitis	0.592	0.407	0.000
M86.6 Other chronic osteomyelitis	0.591	0.408	0.000
Q23 Congenital malformations of aortic and mitral valves	0.591	0.409	0.000
H51 Other disorders of binocular movement	0.591	0.409	0.000
M88 Paget's disease of bone [osteitis deformans]	0.591	0.409	0.000
M21 Other acquired deformities of limbs	0.591	0.409	0.000
Q26 Congenital malformations of great veins	0.590	0.410	0.000
Q25 Congenital malformations of great arteries	0.590	0.410	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.590	0.410	0.000
J38.0 Paralysis of vocal cords and larynx	0.590	0.410	0.000
W13.9 Unspecified place	0.590	0.410	0.000
M65.3 Trigger finger	0.590	0.410	0.000
M66.2 Spontaneous rupture of extensor tendons	0.589	0.411	0.000
L01 Impetigo	0.588	0.411	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.588	0.412	0.000
S98 Traumatic amputation of ankle and foot	0.587	0.413	0.000
S97 Crushing injury of ankle and foot	0.587	0.413	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.587	0.413	0.000
S95 Injury of blood vessels at ankle and foot level	0.587	0.413	0.000
S94 Injury of nerves at ankle and foot level	0.587	0.413	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.587	0.413	0.000
Chapter VIII Diseases of the ear and mastoid process	0.587	0.413	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.586	0.414	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.585	0.415	0.000
H18 Other disorders of cornea	0.584	0.416	0.000
S99.9 Unspecified injury of ankle and foot	0.584	0.416	0.000
G82 Paraplegia and tetraplegia	0.583	0.417	0.000
S02.7 Multiple fractures involving skull and facial bones	0.583	0.417	0.000
H31.0 Chorioretinal scars	0.582	0.417	0.000
M90 Osteopathies in diseases classified elsewhere	0.581	0.418	0.000
M89.9 Disorder of bone, unspecified	0.581	0.419	0.000
M84.03 Malunion of fracture (Forearm)	0.581	0.419	0.000
S32 Fracture of lumbar spine and pelvis	0.580	0.420	0.000
Y35-Y36 Legal intervention and operations of war	0.580	0.420	0.000
Y10-Y34 Event of undetermined intent	0.580	0.420	0.000
X85-X99 Assault	0.580	0.420	0.000
X30-X39 Exposure to forces of nature	0.580	0.420	0.000
X00-X09 Exposure to smoke, fire and flames	0.580	0.420	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.580	0.420	0.000
W75-W84 Other accidental threats to breathing	0.580	0.420	0.000
W65-W74 Accidental drowning and submersion	0.580	0.420	0.000
V95-V97 Air and space transport accidents	0.580	0.420	0.000
V90-V94 Water transport accidents	0.580	0.420	0.000
V70-V79 Bus occupant injured in transport accident	0.580	0.420	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.580	0.420	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.580	0.420	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.580	0.420	0.000
V01-V09 Pedestrian injured in transport accident	0.580	0.420	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.580	0.420	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.579	0.420	0.000
M66.4 Spontaneous rupture of other tendons	0.579	0.420	0.000
M66.1 Rupture of synovium	0.579	0.420	0.000
M65.2 Calcific tendinitis	0.579	0.421	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations