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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3752420
log Bayes Factor = 135.006
Chromosome 6   position 26,027,135  (GRCh37) Explore rs3752420 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.343 0.657
D64.9 Anaemia, unspecified
0.000 0.538 0.462
D64 Other anaemias
0.000 0.748 0.252
D64.4 Congenital dyserythropoietic anaemia
0.000 0.819 0.181
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.819 0.181
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.819 0.181
D64.0 Hereditary sideroblastic anaemia
0.000 0.819 0.181
D64.8 Other specified anaemias
0.000 0.829 0.171
D64.3 Other sideroblastic anaemias
0.000 0.832 0.167
D60-D64 Aplastic and other anaemias
0.000 0.859 0.141
D62 Acute posthaemorrhagic anaemia
0.000 0.866 0.134
K90 Intestinal malabsorption
0.000 0.872 0.128
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.899 0.101
K90.3 Pancreatic steatorrhoea
0.000 0.908 0.092
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.908 0.092
K90.1 Tropical sprue
0.000 0.908 0.092
K90.9 Intestinal malabsorption, unspecified
0.000 0.916 0.084
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.927 0.073
D60.8 Other acquired pure red cell aplasias
0.000 0.927 0.073
D60.1 Transient acquired pure red cell aplasia
0.000 0.927 0.073
D60.0 Chronic acquired pure red cell aplasia
0.000 0.927 0.073
K90.8 Other intestinal malabsorption
0.000 0.927 0.073
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.930 0.070
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.932 0.067
D61 Other aplastic anaemias
0.000 0.935 0.065
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.949 0.050
D61.0 Constitutional aplastic anaemia
0.000 0.951 0.049
D45 Polycythaemia vera
0.047 0.953 0.000
K60.2 Anal fissure, unspecified
0.000 0.953 0.047
D61.8 Other specified aplastic anaemias
0.000 0.953 0.047
D61.3 Idiopathic aplastic anaemia
0.000 0.953 0.047
D61.2 Aplastic anaemia due to other external agents
0.000 0.953 0.047
D50.9 Iron deficiency anaemia, unspecified
0.000 0.957 0.043
D61.1 Drug-induced aplastic anaemia
0.000 0.957 0.043
D63.0 Anaemia in neoplastic disease
0.000 0.958 0.042
F06.7 Mild cognitive disorder
0.040 0.960 0.000
E83 Disorders of mineral metabolism
0.038 0.961 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.966 0.034
E83.9 Disorder of mineral metabolism, unspecified
0.031 0.969 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.031 0.969 0.000
R04.0 Epistaxis
0.029 0.971 0.000
D50 Iron deficiency anaemia
0.000 0.971 0.029
E83.8 Other disorders of mineral metabolism
0.028 0.972 0.000
E83.2 Disorders of zinc metabolism
0.028 0.972 0.000
E83.0 Disorders of copper metabolism
0.028 0.972 0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.027 0.972 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.973 0.027
D50-D53 Nutritional anaemias
0.000 0.973 0.027
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.025 0.975 0.000
F06.2 Organic delusional [schizophrenia-like] disorder
0.024 0.976 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.977 0.023
F06.6 Organic emotionally labile [asthenic] disorder
0.022 0.978 0.000
F06.5 Organic dissociative disorder
0.022 0.978 0.000
F06.4 Organic anxiety disorder
0.022 0.978 0.000
F06.3 Organic mood [affective] disorders
0.022 0.978 0.000
F06.1 Organic catatonic disorder
0.022 0.978 0.000
F06.0 Organic hallucinosis
0.022 0.978 0.000
D50.1 Sideropenic dysphagia
0.000 0.978 0.021
D53 Other nutritional anaemias
0.000 0.979 0.021
R04 Haemorrhage from respiratory passages
0.021 0.979 0.000
D52 Folate deficiency anaemia
0.000 0.980 0.020
D80-D89 Certain disorders involving the immune mechanism
0.000 0.981 0.019
R04.2 Haemoptysis
0.019 0.981 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.983 0.017
R41.3 Other amnesia
0.017 0.983 0.000
D53.9 Nutritional anaemia, unspecified
0.000 0.983 0.016
R04.8 Haemorrhage from other sites in respiratory passages
0.016 0.984 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.984 0.016
D53.8 Other specified nutritional anaemias
0.000 0.985 0.015
D53.2 Scorbutic anaemia
0.000 0.985 0.015
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.985 0.015
D53.0 Protein deficiency anaemia
0.000 0.985 0.015
D83 Common variable immunodeficiency
0.000 0.985 0.015
R04.9 Haemorrhage from respiratory passages, unspecified
0.015 0.985 0.000
K60 Fissure and fistula of anal and rectal regions
0.000 0.985 0.015
R04.1 Haemorrhage from throat
0.015 0.985 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.985 0.015
D52.8 Other folate deficiency anaemias
0.000 0.986 0.014
D52.1 Drug-induced folate deficiency anaemia
0.000 0.986 0.014
D52.0 Dietary folate deficiency anaemia
0.000 0.986 0.014
D52.9 Folate deficiency anaemia, unspecified
0.000 0.986 0.014
D80 Immunodeficiency with predominantly antibody defects
0.000 0.986 0.014
D81 Combined immunodeficiencies
0.000 0.986 0.014
D84 Other immunodeficiencies
0.000 0.986 0.014
K60.1 Chronic anal fissure
0.000 0.986 0.014
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.986 0.014
D55-D59 Haemolytic anaemias
0.000 0.986 0.013
L27 Dermatitis due to substances taken internally
0.000 0.987 0.013
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.987 0.013
D82 Immunodeficiency associated with other major defects
0.000 0.987 0.013
S92.30 Fracture of metatarsal bone (closed)
0.000 0.987 0.013
D83.9 Common variable immunodeficiency, unspecified
0.000 0.988 0.012
D89.1 Cryoglobulinaemia
0.000 0.988 0.012
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.988 0.012
D89.3 Immune reconstitution syndrome
0.000 0.988 0.012
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.988 0.011
E83.3 Disorders of phosphorus metabolism
0.011 0.988 0.001
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.988 0.011
S82.30 Fracture of lower end of tibia (closed)
0.000 0.989 0.011
D83.8 Other common variable immunodeficiencies
0.000 0.989 0.011
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.989 0.011
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.989 0.011
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.989 0.011
K60.3 Anal fistula
0.000 0.989 0.011
S64.4 Injury of digital nerve of other finger
0.011 0.989 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.989 0.011
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.011 0.989 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.989 0.011
D51 Vitamin B12 deficiency anaemia
0.000 0.989 0.011
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.989 0.010
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.989 0.010
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.989 0.010
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.989 0.010
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.989 0.010
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.989 0.010
D84.9 Immunodeficiency, unspecified
0.000 0.990 0.010
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.990 0.010
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.990 0.010
D81.9 Combined immunodeficiency, unspecified
0.000 0.990 0.010
D81.8 Other combined immunodeficiencies
0.000 0.990 0.010
D81.7 Major histocompatibility complex class II deficiency
0.000 0.990 0.010
D81.6 Major histocompatibility complex class I deficiency
0.000 0.990 0.010
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.990 0.010
D81.4 Nezelof's syndrome
0.000 0.990 0.010
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.990 0.010
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.990 0.010
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.990 0.010
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.990 0.010
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.990 0.010
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.990 0.010
D57 Sickle-cell disorders
0.000 0.990 0.010
D55 Anaemia due to enzyme disorders
0.000 0.990 0.010
D84.8 Other specified immunodeficiencies
0.000 0.990 0.010
K60.4 Rectal fistula
0.000 0.990 0.010
D86 Sarcoidosis
0.000 0.990 0.010
D84.1 Defects in the complement system
0.000 0.990 0.010
L27.2 Dermatitis due to ingested food
0.000 0.990 0.010
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.990 0.010
L27.8 Dermatitis due to other substances taken internally
0.000 0.990 0.010
D56 Thalassaemia
0.000 0.990 0.009
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.990 0.009
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.990 0.009
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.990 0.009
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.990 0.009
D82.2 Immunodeficiency with short-limbed stature
0.000 0.990 0.009
D82.0 Wiskott-Aldrich syndrome
0.000 0.990 0.009
D50.8 Other iron deficiency anaemias
0.000 0.991 0.009
S92.3 Fracture of metatarsal bone
0.000 0.991 0.009
D59 Acquired haemolytic anaemia
0.000 0.991 0.009
K60.5 Anorectal fistula
0.000 0.991 0.009
D86.8 Sarcoidosis of other and combined sites
0.000 0.992 0.008
R41 Other symptoms and signs involving cognitive functions and awareness
0.008 0.992 0.000
D82.1 Di George's syndrome
0.000 0.992 0.008
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.992 0.008
D51.2 Transcobalamin II deficiency
0.000 0.992 0.008
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.992 0.008
K90-K93 Other diseases of the digestive system
0.000 0.992 0.008
D56.1 Beta thalassaemia
0.000 0.992 0.007
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.992 0.008
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.993 0.007
D55.8 Other anaemias due to enzyme disorders
0.000 0.993 0.007
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.993 0.007
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.993 0.007
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.993 0.007
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.993 0.007
D57.8 Other sickle-cell disorders
0.000 0.993 0.007
D57.3 Sickle-cell trait
0.000 0.993 0.007
D57.2 Double heterozygous sickling disorders
0.000 0.993 0.007
D57.1 Sickle-cell anaemia without crisis
0.000 0.993 0.007
D57.0 Sickle-cell anaemia with crisis
0.000 0.993 0.007
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.007 0.993 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.993 0.007
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.993 0.007
D56.9 Thalassaemia, unspecified
0.000 0.993 0.007
D56.8 Other thalassaemias
0.000 0.993 0.007
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.993 0.007
D56.2 Delta-beta thalassaemia
0.000 0.993 0.007
D56.0 Alpha thalassaemia
0.000 0.993 0.007
D59.1 Other autoimmune haemolytic anaemias
0.000 0.993 0.007
R41.1 Anterograde amnesia
0.007 0.993 0.000
S92.31 Fracture of metatarsal bone (open)
0.000 0.993 0.007
E10.1 With ketoacidosis
0.000 0.993 0.007
D59.8 Other acquired haemolytic anaemias
0.000 0.993 0.006
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.993 0.006
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.993 0.006
D59.3 Haemolytic-uraemic syndrome
0.000 0.993 0.006
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.993 0.006
K82.4 Cholesterolosis of gallbladder
0.000 0.993 0.007
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.993 0.006
D86.3 Sarcoidosis of skin
0.000 0.993 0.006
D86.0 Sarcoidosis of lung
0.000 0.994 0.006
R41.2 Retrograde amnesia
0.006 0.994 0.000
K60.0 Acute anal fissure
0.000 0.994 0.006
D58 Other hereditary haemolytic anaemias
0.001 0.994 0.006
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.994 0.006
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.994 0.006
Y60.0 During surgical operation
0.000 0.994 0.006
D56.3 Thalassaemia trait
0.000 0.994 0.006
Y60.4 During endoscopic examination
0.000 0.994 0.006
N28.9 Disorder of kidney and ureter, unspecified
0.000 0.994 0.006
S92 Fracture of foot, except ankle
0.000 0.994 0.006
E83.4 Disorders of magnesium metabolism
0.005 0.994 0.001
N28 Other disorders of kidney and ureter, not elsewhere classified
0.000 0.994 0.006
S92.20 Fracture of other tarsal bone(s) (closed)
0.000 0.994 0.006
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.994 0.006
S92.2 Fracture of other tarsal bone(s)
0.000 0.994 0.006
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.000 0.994 0.006
D86.1 Sarcoidosis of lymph nodes
0.000 0.994 0.006
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.994 0.006
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.994 0.005
F00-F09 Organic, including symptomatic, mental disorders
0.006 0.994 0.000
E10.2 With renal complications
0.000 0.994 0.006
M95.0 Acquired deformity of nose
0.006 0.994 0.000
N28.1 Cyst of kidney, acquired
0.000 0.995 0.005
N28.8 Other specified disorders of kidney and ureter
0.000 0.995 0.005
E10.3 With ophthalmic complications
0.000 0.995 0.005
E10 Insulin-dependent diabetes mellitus
0.000 0.995 0.005
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.005 0.995 0.000
Y60.5 During heart catheterisation
0.000 0.995 0.005
N28.0 Ischaemia and infarction of kidney
0.000 0.995 0.005
S92.1 Fracture of talus
0.000 0.995 0.005
F07.0 Organic personality disorder
0.005 0.995 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.995 0.005
D58.8 Other specified hereditary haemolytic anaemias
0.001 0.995 0.004
D58.1 Hereditary elliptocytosis
0.001 0.995 0.004
E21.2 Other hyperparathyroidism
0.000 0.995 0.005
F02 Dementia in other diseases classified elsewhere
0.005 0.995 0.000
S92.9 Fracture of foot, unspecified
0.000 0.995 0.005
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.995 0.005
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.005 0.995 0.000
Y60.8 During other surgical and medical care
0.000 0.995 0.005
Z83.5 Family history of eye and ear disorders
0.005 0.995 0.000
S92.21 Fracture of other tarsal bone(s) (open)
0.000 0.995 0.004
Y60.9 During unspecified surgical and medical care
0.000 0.995 0.004
Y60.7 During administration of enema
0.000 0.995 0.004
Y60.6 During aspiration, puncture and other catheterisation
0.000 0.995 0.004
Y60.3 During injection or immunisation
0.000 0.995 0.004
Y60.2 During kidney dialysis or other perfusion
0.000 0.995 0.004
Y60.1 During infusion or transfusion
0.000 0.995 0.004
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.995 0.004
K93.1 Megacolon in Chagas' disease
0.000 0.995 0.004
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.995 0.004
D58.9 Hereditary haemolytic anaemia, unspecified
0.001 0.996 0.004
S82.3 Fracture of lower end of tibia
0.000 0.996 0.004
S92.10 Fracture of talus (closed)
0.000 0.996 0.004
Z83.3 Family history of diabetes mellitus
0.004 0.996 0.000
F09 Unspecified organic or symptomatic mental disorder
0.004 0.996 0.000
E10.0 With coma
0.000 0.996 0.004
S92.0 Fracture of calcaneus
0.000 0.996 0.004
F02.3 Dementia in Parkinson's disease
0.004 0.996 0.000
S92.7 Multiple fractures of foot
0.000 0.996 0.004
D67 Hereditary factor IX deficiency
0.000 0.996 0.004
D68.9 Coagulation defect, unspecified
0.000 0.996 0.004
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.004 0.996 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.996 0.004
S92.4 Fracture of great toe
0.000 0.996 0.004
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.996 0.004
R52.0 Acute pain
0.004 0.996 0.000
D58.2 Other haemoglobinopathies
0.001 0.996 0.004
E21.4 Other specified disorders of parathyroid gland
0.000 0.996 0.004
D86.9 Sarcoidosis, unspecified
0.000 0.996 0.004
E10.7 With multiple complications
0.000 0.996 0.004
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.004 0.996 0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.004 0.996 0.000
F07.2 Postconcussional syndrome
0.004 0.996 0.000
F07.1 Postencephalitic syndrome
0.004 0.996 0.000
S92.5 Fracture of other toe
0.000 0.996 0.004
S92.11 Fracture of talus (open)
0.000 0.996 0.004
E10.8 With unspecified complications
0.000 0.996 0.004
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.996 0.004
D76.3 Other histiocytosis syndromes
0.000 0.996 0.004
D74 Methaemoglobinaemia
0.000 0.996 0.004
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.996 0.004
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.996 0.004
S00.9 Superficial injury of head, part unspecified
0.000 0.996 0.004
F00 Dementia in Alzheimer's disease
0.004 0.996 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.996 0.004
D69.0 Allergic purpura
0.000 0.996 0.004
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.996 0.004
S92.90 Fracture of foot, unspecified (closed)
0.000 0.996 0.003
E10.6 With other specified complications
0.000 0.996 0.004
M87.9 Osteonecrosis, unspecified
0.004 0.996 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.003 0.996 0.000
F02.2 Dementia in Huntington's disease
0.003 0.996 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.003 0.996 0.000
S92.91 Fracture of foot, unspecified (open)
0.000 0.996 0.003
S61.9 Open wound of wrist and hand, part unspecified
0.004 0.996 0.000
E10.4 With neurological complications
0.000 0.996 0.003
D46.2 Refractory anaemia with excess of blasts
0.003 0.997 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.003 0.997 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.000 0.997 0.003
S92.01 Fracture of calcaneus (open)
0.000 0.997 0.003
S92.71 Multiple fractures of foot (open)
0.000 0.997 0.003
D58.0 Hereditary spherocytosis
0.001 0.997 0.003
D46 Myelodysplastic syndromes
0.003 0.997 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.003 0.997 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.003 0.997 0.000
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.997 0.003
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.997 0.003
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.997 0.003
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.003 0.997 0.000
D68 Other coagulation defects
0.000 0.997 0.003
D46.1 Refractory anaemia with sideroblasts
0.003 0.997 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.003 0.997 0.000
F01 Vascular dementia
0.003 0.997 0.000
Z83 Family history of other specific disorders
0.003 0.997 0.000
K82.2 Perforation of gallbladder
0.000 0.997 0.003
D66 Hereditary factor VIII deficiency
0.000 0.997 0.003
S92.41 Fracture of great toe (open)
0.000 0.997 0.003
C77.1 Intrathoracic lymph nodes
0.000 0.997 0.003
F02.0 Dementia in Pick's disease
0.003 0.997 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.003 0.997 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.003 0.997 0.000
R41.0 Disorientation, unspecified
0.003 0.997 0.000
S92.40 Fracture of great toe (closed)
0.000 0.997 0.003
S92.70 Multiple fractures of foot (closed)
0.000 0.997 0.003
G61.0 Guillain-Barre syndrome
0.000 0.997 0.003
R63.0 Anorexia
0.000 0.997 0.003
S92.00 Fracture of calcaneus (closed)
0.000 0.997 0.003
E10.5 With peripheral circulatory complications
0.000 0.997 0.003
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.003 0.997 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.003 0.997 0.000
C69.3 Choroid
0.000 0.997 0.003
K86.3 Pseudocyst of pancreas
0.000 0.997 0.003
S82.31 Fracture of lower end of tibia (open)
0.000 0.997 0.003
C69.9 Eye, unspecified
0.000 0.997 0.003
D74.9 Methaemoglobinaemia, unspecified
0.000 0.997 0.003
D74.8 Other methaemoglobinaemias
0.000 0.997 0.003
D74.0 Congenital methaemoglobinaemia
0.000 0.997 0.003
D69.4 Other primary thrombocytopenia
0.000 0.997 0.003
S92.51 Fracture of other toe (open)
0.000 0.997 0.003
D69.1 Qualitative platelet defects
0.000 0.997 0.003
R79.0 Abnormal level of blood mineral
0.003 0.997 0.000
C69 Malignant neoplasm of eye and adnexa
0.000 0.997 0.003
D72 Other disorders of white blood cells
0.000 0.997 0.003
E06.3 Autoimmune thyroiditis
0.000 0.997 0.003
E10.9 Without complications
0.000 0.997 0.003
D25.2 Subserosal leiomyoma of uterus
0.000 0.997 0.003
D69.2 Other nonthrombocytopenic purpura
0.000 0.997 0.003
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.003 0.997 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.003 0.997 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.003 0.997 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.003 0.997 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.003 0.997 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.997 0.003
N25-N29 Other disorders of kidney and ureter
0.000 0.997 0.003
D69.8 Other specified haemorrhagic conditions
0.000 0.997 0.003
V23.4 Driver injured in traffic accident
0.000 0.997 0.003
S93.0 Dislocation of ankle joint
0.000 0.997 0.003
K82 Other diseases of gallbladder
0.000 0.997 0.003
D46.5 Refractory anaemia with multi-lineage dysplasia
0.003 0.997 0.000
D73 Diseases of spleen
0.000 0.997 0.003
M87.98 Osteonecrosis, unspecified (Other)
0.003 0.997 0.000
C69.6 Orbit
0.000 0.997 0.003
F00.0 Dementia in Alzheimer's disease with early onset
0.003 0.997 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.003 0.997 0.000
D68.4 Acquired coagulation factor deficiency
0.000 0.997 0.003
R00.8 Other and unspecified abnormalities of heart beat
0.003 0.997 0.000
Z83.6 Family history of diseases of the respiratory system
0.003 0.997 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.003 0.997 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.003 0.997 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.003 0.997 0.000
M95.4 Acquired deformity of chest and rib
0.003 0.997 0.000
F01.1 Multi-infarct dementia
0.003 0.997 0.000
M95.1 Cauliflower ear
0.003 0.997 0.000
S92.50 Fracture of other toe (closed)
0.000 0.997 0.002
N26 Unspecified contracted kidney
0.000 0.997 0.003
D46.7 Other myelodysplastic syndromes
0.003 0.997 0.000
F01.8 Other vascular dementia
0.002 0.997 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.002 0.997 0.000
F01.2 Subcortical vascular dementia
0.002 0.997 0.000
F01.0 Vascular dementia of acute onset
0.002 0.997 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.002 0.997 0.000
D46.4 Refractory anaemia, unspecified
0.003 0.997 0.000
D68.6 Other Thrombophilia
0.000 0.997 0.003
D69.9 Haemorrhagic condition, unspecified
0.000 0.997 0.002
H93.1 Tinnitus
0.003 0.997 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.997 0.003
C69.0 Conjunctiva
0.000 0.997 0.002
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.000 0.997 0.002
K82.1 Hydrops of gallbladder
0.000 0.997 0.003
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.002 0.997 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.003 0.997 0.000
S32.50 Fracture of pubis (closed)
0.000 0.997 0.003
D73.0 Hyposplenism
0.000 0.997 0.003
H54.7 Unspecified visual loss
0.000 0.997 0.003
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.002 0.997 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.002 0.997 0.000
M95.5 Acquired deformity of pelvis
0.002 0.997 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.002 0.997 0.000
A08.4 Viral intestinal infection, unspecified
0.003 0.997 0.000
C48.0 Retroperitoneum
0.000 0.997 0.002
Z83.7 Family history of diseases of the digestive system
0.000 0.998 0.002
C71.1 Frontal lobe
0.000 0.998 0.002
E13.9 Without complications
0.000 0.998 0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.998 0.002
C69.8 Overlapping lesion of eye and adnexa
0.000 0.998 0.002
C69.5 Lachrymal gland and duct
0.000 0.998 0.002
C69.4 Ciliary body
0.000 0.998 0.002
C69.1 Cornea
0.000 0.998 0.002
D72.9 Disorder of white blood cells, unspecified
0.000 0.998 0.002
D72.0 Genetic anomalies of leukocytes
0.000 0.998 0.002
K72.0 Acute and subacute hepatic failure
0.000 0.998 0.002
E28.2 Polycystic ovarian syndrome
0.000 0.998 0.002
G61 Inflammatory polyneuropathy
0.000 0.998 0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.998 0.002
D68.1 Hereditary factor XI deficiency
0.000 0.998 0.002
H90 Conductive and sensorineural hearing loss
0.002 0.998 0.000
H90.0 Conductive hearing loss, bilateral
0.002 0.998 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.000 0.998 0.002
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere
0.000 0.998 0.002
S93.3 Dislocation of other and unspecified parts of foot
0.000 0.998 0.002
Y83.3 Surgical operation with formation of external stoma
0.000 0.998 0.002
C69.2 Retina
0.000 0.998 0.002
D73.3 Abscess of spleen
0.000 0.998 0.002
E27.1 Primary adrenocortical insufficiency
0.000 0.998 0.002
H93 Other disorders of ear, not elsewhere classified
0.002 0.998 0.000
M95.3 Acquired deformity of neck
0.002 0.998 0.000
D73.2 Chronic congestive splenomegaly
0.000 0.998 0.002
K82.8 Other specified diseases of gallbladder
0.000 0.998 0.002
H93.3 Disorders of acoustic nerve
0.002 0.998 0.000
I99 Other and unspecified disorders of circulatory system
0.002 0.998 0.000
R63 Symptoms and signs concerning food and fluid intake
0.000 0.998 0.002
D73.5 Infarction of spleen
0.000 0.998 0.002
E20-E35 Disorders of other endocrine glands
0.000 0.998 0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.998 0.002
K81.0 Acute cholecystitis
0.002 0.998 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.998 0.002
R63.6 Insufficient intake of food and water due to self neglect
0.000 0.998 0.002
F03 Unspecified dementia
0.002 0.998 0.000
D68.8 Other specified coagulation defects
0.000 0.998 0.002
M95.2 Other acquired deformity of head
0.002 0.998 0.000
E28 Ovarian dysfunction
0.000 0.998 0.002
Z83.1 Family history of other infectious and parasitic diseases
0.002 0.998 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.000 0.998 0.002
D72.8 Other specified disorders of white blood cells
0.000 0.998 0.002
D75.0 Familial erythrocytosis
0.000 0.998 0.002
H90.2 Conductive hearing loss, unspecified
0.002 0.998 0.000
N25 Disorders resulting from impaired renal tubular function
0.000 0.998 0.002
G37.9 Demyelinating disease of central nervous system, unspecified
0.002 0.998 0.000
S83.2 Tear of meniscus, current
0.000 0.998 0.002
F05.1 Delirium superimposed on dementia
0.002 0.998 0.000
C71 Malignant neoplasm of brain
0.000 0.998 0.002
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere
0.000 0.998 0.002
N29.0 Late syphilis of kidney
0.000 0.998 0.002
Q28.2 Arteriovenous malformation of cerebral vessels
0.000 0.998 0.002
R63.4 Abnormal weight loss
0.000 0.998 0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.002 0.998 0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified
0.002 0.998 0.000
D73.9 Disease of spleen, unspecified
0.000 0.998 0.002
G61.8 Other inflammatory polyneuropathies
0.000 0.998 0.002
H93.2 Other abnormal auditory perceptions
0.002 0.998 0.000
E13 Other specified diabetes mellitus
0.000 0.998 0.002
R63.3 Feeding difficulties and mismanagement
0.000 0.998 0.002
S90-S99 Injuries to the ankle and foot
0.000 0.998 0.002
D73.4 Cyst of spleen
0.000 0.998 0.002
H90.3 Sensorineural hearing loss, bilateral
0.002 0.998 0.000
Q24.8 Other specified congenital malformations of heart
0.002 0.998 0.000
Q27.3 Peripheral arteriovenous malformation
0.000 0.998 0.002
Y40.8 Other systemic antibiotics
0.000 0.998 0.002
D75 Other diseases of blood and blood-forming organs
0.000 0.998 0.002
D73.1 Hypersplenism
0.000 0.998 0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.998 0.002
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.002 0.998 0.000
Q05.9 Spina bifida, unspecified
0.000 0.998 0.002
E22 Hyperfunction of pituitary gland
0.000 0.998 0.002
G61.1 Serum neuropathy
0.000 0.998 0.002
J93.9 Pneumothorax, unspecified
0.000 0.998 0.002
N27 Small kidney of unknown cause
0.000 0.998 0.002
F05.8 Other delirium
0.002 0.998 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.002 0.998 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.000 0.998 0.002
D68.0 Von Willebrand's disease
0.000 0.998 0.002
H53.2 Diplopia
0.002 0.998 0.000
S93.4 Sprain and strain of ankle
0.000 0.998 0.002
S93.5 Sprain and strain of toe(s)
0.000 0.998 0.002
H93.0 Degenerative and vascular disorders of ear
0.002 0.998 0.000
C71.4 Occipital lobe
0.000 0.998 0.002
C71.0 Cerebrum, except lobes and ventricles
0.000 0.998 0.002
K82.0 Obstruction of gallbladder
0.000 0.998 0.002
E25 Adrenogenital disorders
0.000 0.998 0.002
C71.8 Overlapping lesion of brain
0.000 0.998 0.002
C71.3 Parietal lobe
0.000 0.998 0.002
K75.4 Autoimmune hepatitis
0.000 0.998 0.002
R63.2 Polyphagia
0.000 0.998 0.002
E83.5 Disorders of calcium metabolism
0.001 0.998 0.001
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.000 0.998 0.002
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.998 0.002
E32 Diseases of thymus
0.000 0.998 0.002
E31 Polyglandular dysfunction
0.000 0.998 0.002
E30 Disorders of puberty, not elsewhere classified
0.000 0.998 0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.002 0.998 0.000
S93.6 Sprain and strain of other and unspecified parts of foot
0.000 0.998 0.002
E28.9 Ovarian dysfunction, unspecified
0.000 0.998 0.002
E28.8 Other ovarian dysfunction
0.000 0.998 0.002
E28.1 Androgen excess
0.000 0.998 0.002
E28.0 Oestrogen excess
0.000 0.998 0.002
R63.5 Abnormal weight gain
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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