TreeWAS – Variant ID: rs3752630

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.005	0.995
I21 Acute myocardial infarction	0.000	0.007	0.993
E03.9 Hypothyroidism, unspecified	0.000	0.007	0.993
I20-I25 Ischaemic heart diseases	0.000	0.008	0.992
I25 Chronic ischaemic heart disease	0.000	0.008	0.992
I25.1 Atherosclerotic heart disease	0.000	0.018	0.982
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.021	0.979
I25.5 Ischaemic cardiomyopathy	0.000	0.073	0.927
I22 Subsequent myocardial infarction	0.000	0.085	0.915
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.126	0.874
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.140	0.860
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.140	0.860
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.164	0.836
Z95.0 Presence of cardiac pacemaker	0.000	0.172	0.828
Z95.4 Presence of other heart-valve replacement	0.000	0.191	0.809
I24 Other acute ischaemic heart diseases	0.000	0.193	0.807
Z95.1 Presence of aortocoronary bypass graft	0.000	0.208	0.792
I21.9 Acute myocardial infarction, unspecified	0.000	0.218	0.782
Z95.3 Presence of xenogenic heart valve	0.000	0.237	0.763
I25.4 Coronary artery aneurysm	0.000	0.243	0.757
Z95.2 Presence of prosthetic heart valve	0.000	0.248	0.752
I24.8 Other forms of acute ischaemic heart disease	0.000	0.262	0.738
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.288	0.712
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.289	0.711
I25.6 Silent myocardial ischaemia	0.000	0.289	0.711
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.304	0.696
I23 Certain current complications following acute myocardial infarction	0.000	0.312	0.688
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.342	0.658
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.370	0.630
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.371	0.629
I25.3 Aneurysm of heart	0.000	0.383	0.617
I24.1 Dressler's syndrome	0.000	0.395	0.605
I22.8 Subsequent myocardial infarction of other sites	0.000	0.405	0.595
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.410	0.590
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.411	0.589
I25.2 Old myocardial infarction	0.000	0.417	0.583
E03 Other hypothyroidism	0.000	0.432	0.568
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.457	0.543
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.507	0.493
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.507	0.493
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.507	0.493
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.507	0.493
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.507	0.493
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.507	0.493
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.507	0.493
I23.8 Other current complications following acute myocardial infarction	0.000	0.530	0.470
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.537	0.463
I21.4 Acute subendocardial myocardial infarction	0.000	0.563	0.437
E03.5 Myxoedema coma	0.000	0.592	0.407
E03.4 Atrophy of thyroid (acquired)	0.000	0.592	0.407
E03.3 Postinfectious hypothyroidism	0.000	0.592	0.407
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.592	0.407
E03.8 Other specified hypothyroidism	0.000	0.605	0.395
E03.1 Congenital hypothyroidism without goitre	0.000	0.621	0.378
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.682	0.318
I20 Angina pectoris	0.000	0.771	0.229
Chapter IX Diseases of the circulatory system	0.000	0.778	0.222
I10 Essential (primary) hypertension	0.000	0.779	0.221
I10-I15 Hypertensive diseases	0.000	0.785	0.215
I20.8 Other forms of angina pectoris	0.000	0.789	0.211
E00-E07 Disorders of thyroid gland	0.000	0.795	0.205
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.804	0.196
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.806	0.193
E05.9 Thyrotoxicosis, unspecified	0.000	0.811	0.189
I99 Other and unspecified disorders of circulatory system	0.000	0.818	0.182
I30-I52 Other forms of heart disease	0.000	0.819	0.181
I49 Other cardiac arrhythmias	0.000	0.823	0.177
I50 Heart failure	0.000	0.826	0.174
I49.3 Ventricular premature depolarisation	0.000	0.827	0.173
I24.9 Acute ischaemic heart disease, unspecified	0.001	0.827	0.173
I47 Paroxysmal tachycardia	0.000	0.827	0.173
I49.9 Cardiac arrhythmia, unspecified	0.000	0.827	0.173
I47.2 Ventricular tachycardia	0.000	0.828	0.172
I35 Nonrheumatic aortic valve disorders	0.000	0.832	0.168
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.832	0.168
I50.1 Left ventricular failure	0.000	0.839	0.161
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.839	0.161
I00-I02 Acute rheumatic fever	0.000	0.841	0.159
I35.0 Aortic (valve) stenosis	0.000	0.843	0.157
I13 Hypertensive heart and renal disease	0.000	0.845	0.154
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.847	0.153
I42 Cardiomyopathy	0.000	0.848	0.152
I15 Secondary hypertension	0.000	0.849	0.151
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.850	0.150
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.852	0.148
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.853	0.147
E00 Congenital iodine-deficiency syndrome	0.000	0.853	0.147
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.854	0.146
I50.0 Congestive heart failure	0.000	0.855	0.145
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.857	0.143
I49.0 Ventricular fibrillation and flutter	0.000	0.860	0.140
I50.9 Heart failure, unspecified	0.000	0.861	0.139
E05.5 Thyroid crisis or storm	0.000	0.861	0.139
E05.4 Thyrotoxicosis factitia	0.000	0.861	0.139
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.861	0.139
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.861	0.139
I36 Nonrheumatic tricuspid valve disorders	0.000	0.862	0.138
I97.1 Other functional disturbances following cardiac surgery	0.000	0.867	0.132
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.868	0.132
I33 Acute and subacute endocarditis	0.000	0.869	0.131
I42.0 Dilated cardiomyopathy	0.000	0.869	0.131
I52 Other heart disorders in diseases classified elsewhere	0.000	0.870	0.130
I48 Atrial fibrillation and flutter	0.000	0.870	0.130
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.870	0.130
I41 Myocarditis in diseases classified elsewhere	0.000	0.870	0.130
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.870	0.130
I32 Pericarditis in diseases classified elsewhere	0.000	0.870	0.130
I49.4 Other and unspecified premature depolarisation	0.000	0.870	0.130
E05.8 Other thyrotoxicosis	0.000	0.870	0.129
I49.2 Junctional premature depolarisation	0.000	0.873	0.127
E06 Thyroiditis	0.000	0.873	0.127
I42.9 Cardiomyopathy, unspecified	0.000	0.875	0.125
I35.9 Aortic valve disorder, unspecified	0.000	0.875	0.125
I37 Pulmonary valve disorders	0.000	0.877	0.123
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.879	0.120
I97.0 Postcardiotomy syndrome	0.000	0.879	0.120
I40 Acute myocarditis	0.000	0.881	0.119
I47.0 Reentry ventricular arrhythmia	0.000	0.882	0.118
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.882	0.118
E07 Other disorders of thyroid	0.000	0.885	0.115
I02 Rheumatic chorea	0.000	0.886	0.114
I01 Rheumatic fever with heart involvement	0.000	0.886	0.114
I00 Rheumatic fever without mention of heart involvement	0.000	0.886	0.114
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.889	0.111
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.889	0.111
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.889	0.111
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.889	0.111
I42.5 Other restrictive cardiomyopathy	0.000	0.891	0.109
I42.4 Endocardial fibroelastosis	0.000	0.891	0.109
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.891	0.109
I15.1 Hypertension secondary to other renal disorders	0.000	0.891	0.109
I15.8 Other secondary hypertension	0.000	0.892	0.108
I15.2 Hypertension secondary to endocrine disorders	0.000	0.892	0.108
I15.0 Renovascular hypertension	0.000	0.892	0.108
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.892	0.108
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.892	0.108
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.892	0.108
I98.0 Cardiovascular syphilis	0.000	0.892	0.108
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.892	0.108
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.893	0.107
I42.2 Other hypertrophic cardiomyopathy	0.000	0.893	0.107
I11 Hypertensive heart disease	0.000	0.894	0.106
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.894	0.106
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.894	0.105
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.894	0.105
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.894	0.105
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.894	0.105
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.894	0.105
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.894	0.105
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.894	0.105
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.894	0.105
I49.5 Sick sinus syndrome	0.000	0.896	0.104
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.896	0.104
I15.9 Seconday hypertension, unspecified	0.000	0.896	0.103
I42.6 Alcoholic cardiomyopathy	0.000	0.897	0.102
I85 Oesophageal varices	0.000	0.898	0.102
I30 Acute pericarditis	0.000	0.900	0.100
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.901	0.099
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.901	0.099
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.901	0.099
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.901	0.099
I85.0 Oesophageal varices with bleeding	0.000	0.902	0.098
I33.0 Acute and subacute infective endocarditis	0.000	0.905	0.095
I80 Phlebitis and thrombophlebitis	0.000	0.906	0.094
I33.9 Acute endocarditis, unspecified	0.000	0.906	0.094
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.906	0.093
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.906	0.093
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.906	0.093
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.906	0.093
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.906	0.093
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.906	0.093
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.906	0.093
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.906	0.093
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.906	0.093
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.906	0.093
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.906	0.093
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.906	0.093
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.906	0.093
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.906	0.093
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.906	0.093
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.906	0.093
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.906	0.093
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.906	0.093
I48.4 Atypical atrial flutter	0.000	0.906	0.093
I48.3 Typical atrial flutter	0.000	0.906	0.093
I48.2 Chronic atrial fibrillation	0.000	0.906	0.093
I48.1 Persistent atrial fibrillation	0.000	0.906	0.093
I48.0 Paroxysmal atrial fibrillation	0.000	0.906	0.093
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.906	0.093
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.906	0.093
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.906	0.093
I86 Varicose veins of other sites	0.000	0.906	0.094
E06.4 Drug-induced thyroiditis	0.000	0.909	0.091
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.909	0.091
E06.1 Subacute thyroiditis	0.000	0.909	0.091
E06.0 Acute thyroiditis	0.000	0.909	0.091
I86.4 Gastric varices	0.000	0.909	0.091
E06.9 Thyroiditis, unspecified	0.000	0.910	0.090
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.910	0.090
I35.1 Aortic (valve) insufficiency	0.000	0.911	0.089
I37.9 Pulmonary valve disorder, unspecified	0.000	0.912	0.088
I37.8 Other pulmonary valve disorders	0.000	0.912	0.088
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.912	0.088
I37.0 Pulmonary valve stenosis	0.000	0.912	0.088
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.913	0.087
I35.8 Other aortic valve disorders	0.000	0.914	0.086
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.914	0.086
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.915	0.085
I40.9 Acute myocarditis, unspecified	0.000	0.915	0.085
I40.8 Other acute myocarditis	0.000	0.915	0.085
I40.1 Isolated myocarditis	0.000	0.915	0.085
E06.3 Autoimmune thyroiditis	0.000	0.916	0.084
E07.1 Dyshormogenetic goitre	0.000	0.918	0.082
E07.0 Hypersecretion of calcitonin	0.000	0.918	0.082
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.918	0.082
I01.8 Other acute rheumatic heart disease	0.000	0.918	0.082
I01.2 Acute rheumatic myocarditis	0.000	0.918	0.082
I01.1 Acute rheumatic endocarditis	0.000	0.918	0.082
I01.0 Acute rheumatic pericarditis	0.000	0.918	0.082
I02.9 Rheumatic chorea without heart involvement	0.000	0.918	0.082
I02.0 Rheumatic chorea with heart involvement	0.000	0.918	0.082
I37.1 Pulmonary valve insufficiency	0.000	0.919	0.081
E06.5 Other chronic thyroiditis	0.000	0.919	0.080
I42.8 Other cardiomyopathies	0.000	0.920	0.080
I12 Hypertensive renal disease	0.000	0.921	0.079
I05-I09 Chronic rheumatic heart diseases	0.000	0.922	0.078
I44 Atrioventricular and left bundle-branch block	0.000	0.923	0.077
E07.8 Other specified disorders of thyroid	0.000	0.924	0.076
I85.9 Oesophageal varices without bleeding	0.000	0.924	0.076
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.926	0.073
I40.0 Infective myocarditis	0.000	0.926	0.073
I30.1 Infective pericarditis	0.000	0.928	0.072
I30.8 Other forms of acute pericarditis	0.000	0.928	0.071
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.928	0.071
I38 Endocarditis, valve unspecified	0.000	0.928	0.072
I49.1 Atrial premature depolarisation	0.000	0.929	0.071
I83 Varicose veins of lower extremities	0.000	0.930	0.070
I86.2 Pelvic varices	0.000	0.931	0.069
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.932	0.068
I82 Other venous embolism and thrombosis	0.000	0.932	0.068
I86.3 Vulval varices	0.000	0.933	0.067
I86.0 Sublingual varices	0.000	0.933	0.067
J34.2 Deviated nasal septum	0.066	0.934	0.000
I88 Nonspecific lymphadenitis	0.000	0.934	0.066
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.935	0.064
I44.7 Left bundle-branch block, unspecified	0.000	0.936	0.064
I73 Other peripheral vascular diseases	0.000	0.937	0.063
I45 Other conduction disorders	0.000	0.937	0.063
I26 Pulmonary embolism	0.000	0.940	0.060
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.940	0.060
E07.9 Disorder of thyroid, unspecified	0.000	0.940	0.060
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.941	0.059
I07 Rheumatic tricuspid valve diseases	0.000	0.941	0.059
I44.3 Other and unspecified atrioventricular block	0.000	0.943	0.057
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.943	0.057
I31 Other diseases of pericardium	0.000	0.943	0.057
I28 Other diseases of pulmonary vessels	0.000	0.943	0.056
I73.0 Raynaud's syndrome	0.000	0.943	0.057
I06 Rheumatic aortic valve diseases	0.000	0.944	0.056
I44.5 Left posterior fascicular block	0.000	0.945	0.055
I44.4 Left anterior fascicular block	0.000	0.945	0.055
I78 Diseases of capillaries	0.000	0.946	0.054
I44.6 Other and unspecified fascicular block	0.000	0.946	0.054
I46 Cardiac arrest	0.000	0.947	0.053
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.947	0.053
I86.1 Scrotal varices	0.000	0.948	0.052
I87 Other disorders of veins	0.000	0.949	0.051
I45.4 Nonspecific intraventricular block	0.000	0.950	0.050
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.950	0.050
I12.9 Hypertensive renal disease without renal failure	0.000	0.950	0.050
I82.3 Embolism and thrombosis of renal vein	0.000	0.951	0.049
I82.1 Thrombophlebitis migrans	0.000	0.951	0.049
I82.0 Budd-Chiari syndrome	0.000	0.951	0.049
I73.9 Peripheral vascular disease, unspecified	0.000	0.951	0.049
I73.8 Other specified peripheral vascular diseases	0.000	0.951	0.049
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.951	0.049
I45.9 Conduction disorder, unspecified	0.000	0.952	0.048
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.952	0.047
I88.8 Other nonspecific lymphadenitis	0.000	0.952	0.047
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.952	0.047
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.952	0.047
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.953	0.047
I09 Other rheumatic heart diseases	0.000	0.953	0.047
I45.6 Preexcitation syndrome	0.000	0.953	0.047
I45.2 Bifascicular block	0.000	0.953	0.047
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.953	0.047
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.954	0.046
I81 Portal vein thrombosis	0.000	0.954	0.046
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.954	0.046
I86.8 Varicose veins of other specified sites	0.000	0.954	0.045
I07.1 Tricuspid insufficiency	0.000	0.955	0.045
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.955	0.045
I45.0 Right fascicular block	0.000	0.955	0.045
I82.2 Embolism and thrombosis of vena cava	0.000	0.955	0.044
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.956	0.044
I07.9 Tricuspid valve disease, unspecified	0.000	0.957	0.042
I07.8 Other tricuspid valve diseases	0.000	0.957	0.042
I07.2 Tricuspid stenosis with insufficiency	0.000	0.957	0.042
I07.0 Tricuspid stenosis	0.000	0.957	0.042
I44.2 Atrioventricular block, complete	0.000	0.958	0.042
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.958	0.042
I20.1 Angina pectoris with documented spasm	0.002	0.958	0.040
I78.8 Other diseases of capillaries	0.000	0.958	0.042
I45.5 Other specified heart block	0.000	0.958	0.042
I31.8 Other specified diseases of pericardium	0.000	0.959	0.041
I31.2 Haemopericardium, not elsewhere classified	0.000	0.959	0.041
I31.1 Chronic constrictive pericarditis	0.000	0.959	0.041
I31.0 Chronic adhesive pericarditis	0.000	0.959	0.041
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.959	0.040
I28.1 Aneurysm of pulmonary artery	0.000	0.959	0.040
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.959	0.040
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.960	0.040
I06.8 Other rheumatic aortic valve diseases	0.000	0.960	0.040
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.960	0.040
I06.1 Rheumatic aortic insufficiency	0.000	0.960	0.040
I06.0 Rheumatic aortic stenosis	0.000	0.960	0.040
I30.9 Acute pericarditis, unspecified	0.000	0.960	0.040
I82.8 Embolism and thrombosis of other specified veins	0.000	0.960	0.040
I87.8 Other specified disorders of veins	0.000	0.960	0.040
I78.9 Disease of capillaries, unspecified	0.000	0.961	0.039
I45.8 Other specified conduction disorders	0.000	0.961	0.039
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.961	0.039
I72 Other aneurysm	0.000	0.961	0.038
I74 Arterial embolism and thrombosis	0.000	0.962	0.038
I46.1 Sudden cardiac death, so described	0.000	0.962	0.038
I87.9 Disorder of vein, unspecified	0.000	0.963	0.037
I87.0 Postphlebitic syndrome	0.000	0.963	0.037
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.964	0.036
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.964	0.036
I08 Multiple valve diseases	0.000	0.964	0.036
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.964	0.036
T93.2 Sequelae of other fractures of lower limb	0.036	0.964	0.000
I28.8 Other specified diseases of pulmonary vessels	0.001	0.964	0.035
I20.9 Angina pectoris, unspecified	0.000	0.966	0.034
I44.1 Atrioventricular block, second degree	0.000	0.966	0.034
I09.8 Other specified rheumatic heart diseases	0.000	0.966	0.034
I09.2 Chronic rheumatic pericarditis	0.000	0.966	0.034
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.966	0.034
I09.0 Rheumatic myocarditis	0.000	0.966	0.034
I70 Atherosclerosis	0.000	0.966	0.034
I79.1 Aortitis in diseases classified elsewhere	0.000	0.967	0.033
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.967	0.033
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.967	0.033
I49.8 Other specified cardiac arrhythmias	0.001	0.967	0.033
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.967	0.033
I05 Rheumatic mitral valve diseases	0.000	0.967	0.033
I72.8 Aneurysm of other specified arteries	0.000	0.968	0.032
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.968	0.032
I89.1 Lymphangitis	0.000	0.969	0.031
I78.1 Naevus, nonneoplastic	0.000	0.969	0.031
S22.40 Multiple fractures of ribs (closed)	0.031	0.969	0.000
I44.0 Atrioventricular block, first degree	0.000	0.969	0.031
S22 Fracture of rib(s), sternum and thoracic spine	0.031	0.969	0.000
S22.4 Multiple fractures of ribs	0.031	0.969	0.000
E04 Other non-toxic goitre	0.000	0.969	0.031
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.969	0.030
S66 Injury of muscle and tendon at wrist and hand level	0.030	0.970	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.029	0.971	0.000
S20-S29 Injuries to the thorax	0.029	0.971	0.000
R25.1 Tremor, unspecified	0.029	0.971	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.971	0.029
R25 Abnormal involuntary movements	0.028	0.972	0.000
I95 Hypotension	0.000	0.972	0.028
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.972	0.028
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.028	0.972	0.000
S22.0 Fracture of thoracic vertebra	0.028	0.972	0.000
I72.9 Aneurysm of unspecified site	0.000	0.972	0.028
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.972	0.028
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.972	0.028
I72.2 Aneurysm of renal artery	0.000	0.972	0.028
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.972	0.028
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.972	0.028
S27 Injury of other and unspecified intrathoracic organs	0.028	0.972	0.000
R25.2 Cramp and spasm	0.027	0.973	0.000
I77 Other disorders of arteries and arterioles	0.000	0.973	0.027
S32 Fracture of lumbar spine and pelvis	0.027	0.973	0.000
S27.0 Traumatic pneumothorax	0.027	0.973	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.027	0.973	0.000
S60-S69 Injuries to the wrist and hand	0.027	0.973	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.026	0.974	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.974	0.026
S32.0 Fracture of lumbar vertebra	0.026	0.974	0.000
T92 Sequelae of injuries of upper limb	0.026	0.974	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.026	0.974	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.026	0.974	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.974	0.026
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.974	0.026
T43.2 Other and unspecified antidepressants	0.026	0.974	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.026	0.974	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.026	0.974	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.026	0.974	0.000
I72.1 Aneurysm of artery of upper extremity	0.000	0.975	0.025
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.025	0.975	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.975	0.025
I09.9 Rheumatic heart disease, unspecified	0.001	0.975	0.025
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.025	0.975	0.000
T93 Sequelae of injuries of lower limb	0.025	0.975	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.025	0.975	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.025	0.975	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.975	0.024
I72.4 Aneurysm of artery of lower extremity	0.000	0.975	0.024
S22.1 Multiple fractures of thoracic spine	0.024	0.976	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.976	0.024
T92.1 Sequelae of fracture of arm	0.024	0.976	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.976	0.024
I05.8 Other mitral valve diseases	0.000	0.976	0.024
S65 Injury of blood vessels at wrist and hand level	0.024	0.976	0.000
I45.3 Trifascicular block	0.001	0.976	0.023
I74.8 Embolism and thrombosis of other arteries	0.000	0.976	0.023
I51 Complications and ill-defined descriptions of heart disease	0.000	0.976	0.024
S32.4 Fracture of acetabulum	0.024	0.976	0.000
I87.1 Compression of vein	0.000	0.976	0.023
I72.3 Aneurysm of iliac artery	0.000	0.977	0.023
T92.0 Sequelae of open wound of upper limb	0.023	0.977	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.023	0.977	0.000
S22.5 Flail chest	0.023	0.977	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.023	0.977	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.977	0.023
S22.3 Fracture of rib	0.023	0.977	0.000
I72.0 Aneurysm of carotid artery	0.000	0.977	0.023
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.023	0.977	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.977	0.023
I70.8 Atherosclerosis of other arteries	0.000	0.977	0.023
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.977	0.023
I77.6 Arteritis, unspecified	0.000	0.977	0.023
S36 Injury of intra-abdominal organs	0.023	0.977	0.000
S22.9 Fracture of bony thorax, part unspecified	0.022	0.977	0.000
S22.8 Fracture of other parts of bony thorax	0.022	0.977	0.000
S27.2 Traumatic heamopneumothorax	0.022	0.978	0.000
R26 Abnormalities of gait and mobility	0.022	0.978	0.000
S64 Injury of nerves at wrist and hand level	0.022	0.978	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.022	0.978	0.000
S22.41 Multiple fractures of ribs (open)	0.022	0.978	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.978	0.022
T92.8 Sequelae of other specified injuries of upper limb	0.022	0.978	0.000
S69 Other and unspecified injuries of wrist and hand	0.022	0.978	0.000
S10-S19 Injuries to the neck	0.022	0.978	0.000
E04.8 Other specified non-toxic goitre	0.000	0.978	0.022
T20-T25 Burns and corrosions of external body surface, specified by site	0.022	0.978	0.000
I05.0 Mitral stenosis	0.000	0.978	0.022
S61.9 Open wound of wrist and hand, part unspecified	0.022	0.978	0.000
T98 Sequelae of other and unspecified effects of external causes	0.022	0.978	0.000
I71 Aortic aneurysm and dissection	0.000	0.978	0.022
T31 Burns classified according to extent of body surface involved	0.022	0.978	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.022	0.978	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.022	0.978	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.022	0.978	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.022	0.978	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.022	0.978	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.021	0.978	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.021	0.978	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.022	0.978	0.000
I47.1 Supraventricular tachycardia	0.000	0.979	0.021
R26.3 Immobility	0.021	0.979	0.000
S61 Open wound of wrist and hand	0.021	0.979	0.000
I08.8 Other multiple valve diseases	0.000	0.979	0.021
I05.1 Rheumatic mitral insufficiency	0.000	0.979	0.021
S32.40 Fracture of acetabulum (closed)	0.021	0.979	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.021	0.979	0.000
S26 Injury of heart	0.021	0.979	0.000
S25 Injury of blood vessels of thorax	0.021	0.979	0.000
S24 Injury of nerves and spinal cord at thorax level	0.021	0.979	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.021	0.979	0.000
S65.5 Injury of blood vessel(s) of other finger	0.021	0.979	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.979	0.021
T43.3 Phenothiazine antipsychotics and neuroleptics	0.021	0.979	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.979	0.021
R25.0 Abnormal head movements	0.021	0.979	0.000
S10 Superficial injury of neck	0.021	0.979	0.000
S21 Open wound of thorax	0.020	0.979	0.000
S27.3 Other injuries of lung	0.020	0.979	0.000
R27 Other lack of coordination	0.020	0.980	0.000
S22.01 Fracture of thoracic vertebra (open)	0.020	0.980	0.000
S32.1 Fracture of sacrum	0.020	0.980	0.000
T95 Sequelae of burns, corrosions and frostbite	0.020	0.980	0.000
S32.3 Fracture of ilium	0.020	0.980	0.000
S27.9 Injury of unspecified intrathoracic organ	0.020	0.980	0.000
S27.8 Injury of other specified intrathoracic organs	0.020	0.980	0.000
S27.7 Multiple injuries of intrathoracic organs	0.020	0.980	0.000
S27.6 Injury of pleura	0.020	0.980	0.000
S27.5 Injury of thoracic trachea	0.020	0.980	0.000
S27.4 Injury of bronchus	0.020	0.980	0.000
T31.0 Burns involving less than 10% of body surface	0.020	0.980	0.000
S37 Injury of urinary and pelvic organs	0.020	0.980	0.000
I95.8 Other hypotension	0.000	0.980	0.020
I95.2 Hypotension due to drugs	0.000	0.980	0.020
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.020	0.980	0.000
S29 Other and unspecified injuries of thorax	0.020	0.980	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.020	0.980	0.000
I77.5 Necrosis of artery	0.000	0.980	0.020
I77.4 Coeliac artery compression syndrome	0.000	0.980	0.020
I77.3 Arterial fibromuscular dysplasia	0.000	0.980	0.020
I77.2 Rupture of artery	0.000	0.980	0.020
S32.2 Fracture of coccyx	0.020	0.980	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.020	0.980	0.000
S22.2 Fracture of sternum	0.020	0.980	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.019	0.980	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.020	0.980	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.020	0.980	0.000
I70.0 Atherosclerosis of aorta	0.000	0.980	0.019

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations