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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3752728
log Bayes Factor = 6.24552
Chromosome 12   position 20,192,972  (GRCh37) Explore rs3752728 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.013 0.987
I25 Chronic ischaemic heart disease
0.000 0.020 0.980
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.038 0.962
I25.5 Ischaemic cardiomyopathy
0.000 0.101 0.899
I25.2 Old myocardial infarction
0.000 0.142 0.858
I25.4 Coronary artery aneurysm
0.000 0.184 0.816
I25.6 Silent myocardial ischaemia
0.000 0.297 0.703
I20-I25 Ischaemic heart diseases
0.000 0.324 0.676
I25.3 Aneurysm of heart
0.000 0.328 0.672
I20 Angina pectoris
0.000 0.366 0.634
I20.8 Other forms of angina pectoris
0.000 0.400 0.600
I20.9 Angina pectoris, unspecified
0.000 0.413 0.587
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.428 0.572
I23 Certain current complications following acute myocardial infarction
0.000 0.477 0.523
I24 Other acute ischaemic heart diseases
0.000 0.510 0.490
I24.8 Other forms of acute ischaemic heart disease
0.000 0.547 0.453
I25.0 Atherosclerotic cardiovascular disease, so described
0.001 0.549 0.451
I20.1 Angina pectoris with documented spasm
0.000 0.568 0.432
I23.8 Other current complications following acute myocardial infarction
0.000 0.587 0.413
I24.1 Dressler's syndrome
0.000 0.606 0.394
I22 Subsequent myocardial infarction
0.000 0.614 0.386
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.625 0.375
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.625 0.375
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.625 0.375
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.625 0.375
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.625 0.375
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.625 0.375
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.625 0.375
I21 Acute myocardial infarction
0.000 0.631 0.369
I10-I15 Hypertensive diseases
0.000 0.648 0.352
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.688 0.312
I22.8 Subsequent myocardial infarction of other sites
0.000 0.717 0.283
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.729 0.271
I12 Hypertensive renal disease
0.000 0.735 0.265
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.735 0.265
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.746 0.253
I13 Hypertensive heart and renal disease
0.000 0.747 0.253
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.750 0.250
I21.9 Acute myocardial infarction, unspecified
0.000 0.753 0.247
I12.9 Hypertensive renal disease without renal failure
0.000 0.754 0.246
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.759 0.241
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.768 0.232
I21.4 Acute subendocardial myocardial infarction
0.000 0.786 0.214
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.798 0.202
I11 Hypertensive heart disease
0.000 0.812 0.188
I15 Secondary hypertension
0.000 0.818 0.182
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.819 0.181
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.819 0.181
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.819 0.181
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.819 0.181
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.820 0.180
Chapter IX Diseases of the circulatory system
0.000 0.836 0.164
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.858 0.142
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.864 0.136
I15.8 Other secondary hypertension
0.000 0.869 0.131
I15.2 Hypertension secondary to endocrine disorders
0.000 0.869 0.131
I00-I02 Acute rheumatic fever
0.000 0.880 0.119
I15.0 Renovascular hypertension
0.000 0.883 0.117
I15.1 Hypertension secondary to other renal disorders
0.000 0.887 0.112
I15.9 Seconday hypertension, unspecified
0.000 0.889 0.111
I00 Rheumatic fever without mention of heart involvement
0.000 0.912 0.088
I02 Rheumatic chorea
0.000 0.914 0.086
I01 Rheumatic fever with heart involvement
0.000 0.914 0.086
I20.0 Unstable angina
0.000 0.924 0.076
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.930 0.069
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.935 0.065
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.938 0.062
I01.8 Other acute rheumatic heart disease
0.000 0.938 0.062
I01.2 Acute rheumatic myocarditis
0.000 0.938 0.062
I01.1 Acute rheumatic endocarditis
0.000 0.938 0.062
I01.0 Acute rheumatic pericarditis
0.000 0.938 0.062
I02.9 Rheumatic chorea without heart involvement
0.000 0.938 0.062
I02.0 Rheumatic chorea with heart involvement
0.000 0.938 0.062
I28 Other diseases of pulmonary vessels
0.000 0.952 0.047
I28.8 Other specified diseases of pulmonary vessels
0.000 0.961 0.039
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.961 0.039
I28.1 Aneurysm of pulmonary artery
0.000 0.966 0.034
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.966 0.034
I27 Other pulmonary heart diseases
0.000 0.969 0.031
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.972 0.028
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.972 0.028
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.972 0.028
C44.0 Skin of lip
0.027 0.973 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.975 0.025
I26 Pulmonary embolism
0.000 0.976 0.024
I27.9 Pulmonary heart disease, unspecified
0.000 0.977 0.023
I27.1 Kyphoscoliotic heart disease
0.000 0.978 0.022
I27.8 Other specified pulmonary heart diseases
0.000 0.978 0.022
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.979 0.021
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.979 0.020
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.980 0.020
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.980 0.020
I98.0 Cardiovascular syphilis
0.000 0.980 0.020
I27.0 Primary pulmonary hypertension
0.000 0.980 0.020
I97.0 Postcardiotomy syndrome
0.000 0.981 0.019
I97.1 Other functional disturbances following cardiac surgery
0.000 0.981 0.019
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.981 0.019
I05-I09 Chronic rheumatic heart diseases
0.001 0.982 0.017
I12.0 Hypertensive renal disease with renal failure
0.000 0.983 0.017
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.983 0.017
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.984 0.016
I99 Other and unspecified disorders of circulatory system
0.000 0.987 0.012
I06 Rheumatic aortic valve diseases
0.001 0.988 0.012
I09 Other rheumatic heart diseases
0.001 0.988 0.011
J32.0 Chronic maxillary sinusitis
0.000 0.989 0.011
S02.20 Fracture of nasal bones (closed)
0.011 0.989 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.990 0.010
I06.0 Rheumatic aortic stenosis
0.001 0.991 0.009
I06.9 Rheumatic aortic valve disease, unspecified
0.001 0.991 0.008
I06.8 Other rheumatic aortic valve diseases
0.001 0.991 0.008
I06.2 Rheumatic aortic stenosis with insufficiency
0.001 0.991 0.008
I07 Rheumatic tricuspid valve diseases
0.001 0.991 0.008
I09.8 Other specified rheumatic heart diseases
0.001 0.991 0.008
I09.2 Chronic rheumatic pericarditis
0.001 0.991 0.008
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.001 0.991 0.008
I09.0 Rheumatic myocarditis
0.001 0.991 0.008
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.000 0.991 0.009
C78.7 Secondary malignant neoplasm of liver
0.000 0.991 0.009
H18.8 Other specified disorders of cornea
0.000 0.991 0.009
I06.1 Rheumatic aortic insufficiency
0.001 0.992 0.008
Z63.7 Other stressful life events affecting family and household
0.008 0.992 0.000
H18.4 Corneal degeneration
0.000 0.992 0.008
Z63 Other problems related to primary support group, including family circumstances
0.008 0.992 0.000
Z63.0 Problems in relationship with spouse or partner
0.008 0.992 0.000
I09.9 Rheumatic heart disease, unspecified
0.001 0.992 0.007
M22.8 Other disorders of patella
0.008 0.992 0.000
J32 Chronic sinusitis
0.000 0.992 0.008
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.992 0.008
H18 Other disorders of cornea
0.000 0.993 0.007
H18.5 Hereditary corneal dystrophies
0.000 0.993 0.007
Z63.8 Other specified problems related to primary support group
0.007 0.993 0.000
C81.9 Hodgkin's disease, unspecified
0.000 0.993 0.007
H18.6 Keratoconus
0.000 0.993 0.007
Z63.6 Dependent relative needing care at home
0.007 0.993 0.000
I07.9 Tricuspid valve disease, unspecified
0.001 0.993 0.006
I07.8 Other tricuspid valve diseases
0.001 0.993 0.006
I07.2 Tricuspid stenosis with insufficiency
0.001 0.993 0.006
I07.0 Tricuspid stenosis
0.001 0.993 0.006
J32.2 Chronic ethmoidal sinusitis
0.000 0.993 0.007
J32.1 Chronic frontal sinusitis
0.000 0.993 0.007
S02.2 Fracture of nasal bones
0.007 0.993 0.000
Z63.4 Disappearance and death of family member
0.006 0.994 0.000
E21.0 Primary hyperparathyroidism
0.000 0.994 0.006
Y45.0 Opioids and related analgesics
0.000 0.994 0.006
J32.3 Chronic sphenoidal sinusitis
0.000 0.994 0.006
Z63.9 Problem related to primary support group, unspecified
0.006 0.994 0.000
Z63.3 Absence of family member
0.006 0.994 0.000
Z63.2 Inadequate family support
0.006 0.994 0.000
Z63.1 Problems in relationship with parents and in-laws
0.006 0.994 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.994 0.006
M22.2 Patellofemoral disorders
0.006 0.994 0.000
I71 Aortic aneurysm and dissection
0.000 0.994 0.006
E78.0 Pure hypercholesterolaemia
0.000 0.994 0.006
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.994 0.006
J32.9 Chronic sinusitis, unspecified
0.000 0.994 0.006
C20 Malignant neoplasm of rectum
0.000 0.994 0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.994 0.006
Z63.5 Disruption of family by separation and divorce
0.006 0.994 0.000
Z89.5 Acquired absence of leg at or below knee
0.006 0.994 0.000
E11.5 With peripheral circulatory complications
0.006 0.994 0.000
H18.7 Other corneal deformities
0.000 0.994 0.005
Z89.4 Acquired absence of foot and ankle
0.006 0.994 0.000
Z89 Acquired absence of limb
0.005 0.995 0.000
M22 Disorders of patella
0.005 0.995 0.000
J32.8 Other chronic sinusitis
0.000 0.995 0.005
S02.21 Fracture of nasal bones (open)
0.005 0.995 0.000
H18.0 Corneal pigmentations and deposits
0.000 0.995 0.005
J32.4 Chronic pansinusitis
0.000 0.995 0.005
Z89.8 Acquired absence of upper and lower limbs [any level]
0.005 0.995 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.995 0.005
H18.1 Bullous keratopathy
0.000 0.995 0.005
Z89.6 Acquired absence of leg above knee
0.005 0.995 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.005 0.995 0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]
0.005 0.995 0.000
H53.0 Amblyopia ex anopsia
0.005 0.995 0.000
H18.3 Changes in corneal membranes
0.000 0.995 0.004
H18.9 Disorder of cornea, unspecified
0.000 0.995 0.004
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.995 0.005
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.996 0.004
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.996 0.004
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.996 0.004
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.996 0.004
E11.6 With other specified complications
0.004 0.996 0.000
N43.3 Hydrocele, unspecified
0.004 0.996 0.000
I05 Rheumatic mitral valve diseases
0.002 0.996 0.002
H18.2 Other corneal oedema
0.000 0.996 0.004
F06.7 Mild cognitive disorder
0.004 0.996 0.000
M22.3 Other derangements of patella
0.004 0.996 0.000
Z89.3 Acquired absence of both upper limbs [any level]
0.004 0.996 0.000
Z89.1 Acquired absence of hand and wrist
0.004 0.996 0.000
M22.1 Recurrent subluxation of patella
0.004 0.996 0.000
M86.9 Osteomyelitis, unspecified
0.004 0.996 0.000
M22.0 Recurrent dislocation of patella
0.004 0.996 0.000
I08 Multiple valve diseases
0.000 0.996 0.004
M22.9 Disorder of patella, unspecified
0.004 0.996 0.000
Z89.9 Acquired absence of limb, unspecified
0.004 0.996 0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.004 0.996 0.000
Z89.2 Acquired absence of upper limb above wrist
0.004 0.996 0.000
N48.6 Balanitis xerotica obliterans
0.004 0.996 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.004 0.996 0.000
N02.8 Other
0.004 0.996 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.996 0.004
M22.4 Chondromalacia patellae
0.004 0.996 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.003 0.996 0.000
I71.0 Dissection of aorta [any part]
0.000 0.997 0.003
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.997 0.003
M86.94 Osteomyelitis, unspecified (Hand)
0.003 0.997 0.000
I05.8 Other mitral valve diseases
0.002 0.997 0.002
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.003 0.997 0.000
M22.10 Recurrent subluxation of patella, unspecified knee
0.003 0.997 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.003 0.997 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.003 0.997 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.003 0.997 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.003 0.997 0.000
I08.9 Multiple valve disease, unspecified
0.000 0.997 0.003
M07.3 Other psoriatic arthropathies
0.000 0.997 0.003
I08.8 Other multiple valve diseases
0.000 0.997 0.003
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.997 0.003
D21.2 Connective and other soft tissue of lower limb, including hip
0.000 0.997 0.003
Z74.0 Reduced mobility
0.000 0.997 0.003
I05.1 Rheumatic mitral insufficiency
0.002 0.997 0.001
H47.3 Other disorders of optic disk
0.003 0.997 0.000
I05.2 Mitral stenosis with insufficiency
0.002 0.997 0.001
I05.0 Mitral stenosis
0.002 0.997 0.001
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.003 0.997 0.000
S00.9 Superficial injury of head, part unspecified
0.003 0.997 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.003 0.997 0.000
E34.9 Endocrine disorder, unspecified
0.003 0.997 0.000
O69.8 Labour and delivery complicated by other cord complications
0.003 0.997 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.997 0.003
M86 Osteomyelitis
0.003 0.997 0.000
E21.3 Hyperparathyroidism, unspecified
0.003 0.997 0.000
R76.8 Other specified abnormal immunological findings in serum
0.003 0.997 0.000
I07.1 Tricuspid insufficiency
0.002 0.997 0.001
E21.5 Disorder of parathyroid gland, unspecified
0.003 0.997 0.000
E24.9 Cushing's syndrome, unspecified
0.003 0.997 0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.997 0.003
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.997 0.003
E21.2 Other hyperparathyroidism
0.003 0.997 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.997 0.003
I05.9 Mitral valve disease, unspecified
0.002 0.997 0.001
E34 Other endocrine disorders
0.003 0.997 0.000
E24 Cushing's syndrome
0.003 0.997 0.000
I70 Atherosclerosis
0.000 0.997 0.003
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.997 0.003
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.003 0.997 0.000
Z58.8 Other problems related to physical environment
0.003 0.997 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.003 0.997 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.003 0.997 0.000
I79.1 Aortitis in diseases classified elsewhere
0.000 0.997 0.002
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.997 0.002
S02 Fracture of skull and facial bones
0.003 0.997 0.000
E34.8 Other specified endocrine disorders
0.003 0.997 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.003 0.997 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.003 0.997 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.997 0.003
E11 Non-insulin-dependent diabetes mellitus
0.003 0.997 0.000
E24.0 Pituitary-dependent Cushing's disease
0.003 0.997 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.997 0.003
I73 Other peripheral vascular diseases
0.000 0.997 0.003
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.003 0.997 0.000
I74 Arterial embolism and thrombosis
0.000 0.997 0.003
E11.2 With renal complications
0.003 0.997 0.000
K50.9 Crohn's disease, unspecified
0.003 0.997 0.000
M86.6 Other chronic osteomyelitis
0.002 0.997 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.997 0.002
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.997 0.002
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.997 0.002
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.997 0.002
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.997 0.002
I78 Diseases of capillaries
0.000 0.997 0.003
M86.4 Chronic osteomyelitis with draining sinus
0.002 0.997 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.002 0.997 0.000
M86.1 Other acute osteomyelitis
0.002 0.997 0.000
S02.6 Fracture of mandible
0.002 0.997 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.998 0.002
Z58 Problems related to physical environment
0.002 0.998 0.000
T23 Burn and corrosion of wrist and hand
0.000 0.998 0.002
E28.3 Primary ovarian failure
0.002 0.998 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.998 0.002
M21.1 Varus deformity, not elsewhere classified
0.002 0.998 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.000 0.998 0.002
E21.4 Other specified disorders of parathyroid gland
0.002 0.998 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.002 0.998 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.002 0.998 0.000
M86.3 Chronic multifocal osteomyelitis
0.002 0.998 0.000
M86.2 Subacute osteomyelitis
0.002 0.998 0.000
M86.0 Acute haematogenous osteomyelitis
0.002 0.998 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.998 0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.002 0.998 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.998 0.002
S02.4 Fracture of malar and maxillary bones
0.002 0.998 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
S02.60 Fracture of mandible (closed)
0.002 0.998 0.000
E24.2 Drug-induced Cushing's syndrome
0.002 0.998 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.002 0.998 0.000
S02.7 Multiple fractures involving skull and facial bones
0.002 0.998 0.000
T23.3 Burn of third degree of wrist and hand
0.000 0.998 0.002
I70.1 Atherosclerosis of renal artery
0.000 0.998 0.002
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.002 0.998 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.000 0.998 0.002
E20-E35 Disorders of other endocrine glands
0.002 0.998 0.000
I60-I69 Cerebrovascular diseases
0.000 0.998 0.002
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.998 0.002
E34.5 Androgen resistance syndrome
0.002 0.998 0.000
E34.4 Constitutional tall stature
0.002 0.998 0.000
E34.3 Short stature, not elsewhere classified
0.002 0.998 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.002 0.998 0.000
E34.1 Other hypersecretion of intestinal hormones
0.002 0.998 0.000
M86.8 Other osteomyelitis
0.002 0.998 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.002 0.998 0.000
Z61 Problems related to negative life events in childhood
0.002 0.998 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.998 0.002
E24.8 Other Cushing's syndrome
0.002 0.998 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.002 0.998 0.000
E24.3 Ectopic ACTH syndrome
0.002 0.998 0.000
E24.1 Nelson's syndrome
0.002 0.998 0.000
E34.0 Carcinoid syndrome
0.002 0.998 0.000
G80.9 Infantile cerebral palsy, unspecified
0.002 0.998 0.000
K50.8 Other Crohn's disease
0.002 0.998 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.000 0.998 0.002
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.998 0.002
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
T79.8 Other early complications of trauma
0.002 0.998 0.000
E28 Ovarian dysfunction
0.002 0.998 0.000
Z56 Problems related to employment and unemployment
0.002 0.998 0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)
0.002 0.998 0.000
C02.9 Tongue, unspecified
0.000 0.998 0.002
K50.1 Crohn's disease of large intestine
0.002 0.998 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.000 0.998 0.002
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
I95 Hypotension
0.000 0.998 0.002
I73.8 Other specified peripheral vascular diseases
0.000 0.998 0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.002 0.998 0.000
I70.9 Generalised and unspecified atherosclerosis
0.000 0.998 0.002
T23.2 Burn of second degree of wrist and hand
0.000 0.998 0.002
M86.17 Other acute osteomyelitis (Ankle and foot)
0.002 0.998 0.000
E11.7 With multiple complications
0.002 0.998 0.000
R12 Heartburn
0.002 0.998 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.002 0.998 0.000
C78.0 Secondary malignant neoplasm of lung
0.000 0.998 0.002
I70.8 Atherosclerosis of other arteries
0.000 0.998 0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.998 0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.998 0.002
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium
0.000 0.998 0.002
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium
0.000 0.998 0.002
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium
0.000 0.998 0.002
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
E25 Adrenogenital disorders
0.002 0.998 0.000
E11.3 With ophthalmic complications
0.002 0.998 0.000
Z65 Problems related to other psychosocial circumstances
0.002 0.998 0.000
Z62 Other problems related to upbringing
0.002 0.998 0.000
Z55 Problems related to education and literacy
0.002 0.998 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.68 Other chronic osteomyelitis (Other)
0.002 0.998 0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.64 Other chronic osteomyelitis (Hand)
0.002 0.998 0.000
M86.63 Other chronic osteomyelitis (Forearm)
0.002 0.998 0.000
M86.62 Other chronic osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.61 Other chronic osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.60 Other chronic osteomyelitis (Multiple sites)
0.002 0.998 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.998 0.002
S02.40 Fracture of malar and maxillary bones (closed)
0.002 0.998 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.998 0.002
Z56.6 Other physical and mental strain related to work
0.002 0.998 0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)
0.002 0.998 0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)
0.002 0.998 0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)
0.002 0.998 0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)
0.002 0.998 0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)
0.002 0.998 0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)
0.002 0.998 0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)
0.002 0.998 0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)
0.002 0.998 0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)
0.002 0.998 0.000
M86.66 Other chronic osteomyelitis (Lower leg)
0.002 0.998 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.002 0.998 0.000
S02.70 Multiple fractures involving skull and facial bones (closed)
0.002 0.998 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.998 0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.002 0.998 0.000
T23.1 Burn of first degree of wrist and hand
0.000 0.998 0.002
M86.19 Other acute osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.18 Other acute osteomyelitis (Other)
0.002 0.998 0.000
M86.16 Other acute osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.14 Other acute osteomyelitis (Hand)
0.002 0.998 0.000
M86.13 Other acute osteomyelitis (Forearm)
0.002 0.998 0.000
M86.12 Other acute osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.11 Other acute osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.10 Other acute osteomyelitis (Multiple sites)
0.002 0.998 0.000
S02.61 Fracture of mandible (open)
0.002 0.998 0.000
G82.1 Spastic paraplegia
0.002 0.998 0.000
S02.3 Fracture of orbital floor
0.002 0.998 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.002 0.998 0.000
Z58.5 Exposure to other pollution
0.002 0.998 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.002 0.998 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.000 0.998 0.002
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.998 0.002
G80 Infantile cerebral palsy
0.002 0.998 0.000
Z64 Problems related to certain psychosocial circumstances
0.002 0.998 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.998 0.002
C78.2 Secondary malignant neoplasm of pleura
0.000 0.998 0.002
T23.7 Corrosion of third degree of wrist and hand
0.000 0.998 0.002
T23.6 Corrosion of second degree of wrist and hand
0.000 0.998 0.002
T23.5 Corrosion of first degree of wrist and hand
0.000 0.998 0.002
T23.4 Corrosion of unspecified degree of wrist and hand
0.000 0.998 0.002
Z58.9 Problem related to physical environment, unspecified
0.002 0.998 0.000
Z58.7 Exposure to tobacco smoke
0.002 0.998 0.000
Z58.6 Inadequate drinking-water supply
0.002 0.998 0.000
Z58.4 Exposure to radiation
0.002 0.998 0.000
Z58.3 Exposure to soil pollution
0.002 0.998 0.000
Z58.2 Exposure to water pollution
0.002 0.998 0.000
Z58.0 Exposure to noise
0.002 0.998 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.002 0.998 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.000 0.998 0.002
M19.92 Arthrosis, unspecified (Upper arm)
0.000 0.998 0.002
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.002 0.998 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.002 0.998 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.002 0.998 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.002 0.998 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.002 0.998 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.002 0.998 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.002 0.998 0.000
G80.1 Spastic diplegia
0.002 0.998 0.000
Q89.2 Congenital malformations of other endocrine glands
0.002 0.998 0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group
0.002 0.998 0.000
K50 Crohn's disease [regional enteritis]
0.002 0.998 0.000
O15 Eclampsia
0.000 0.998 0.002
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.002 0.998 0.000
I73.0 Raynaud's syndrome
0.000 0.998 0.002
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.002 0.998 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.998 0.002
M86.09 Acute haematogenous osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.08 Acute haematogenous osteomyelitis (Other)
0.002 0.998 0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.04 Acute haematogenous osteomyelitis (Hand)
0.002 0.998 0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)
0.002 0.998 0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.29 Subacute osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.28 Subacute osteomyelitis (Other)
0.002 0.998 0.000
M86.27 Subacute osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.26 Subacute osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.24 Subacute osteomyelitis (Hand)
0.002 0.998 0.000
M86.23 Subacute osteomyelitis (Forearm)
0.002 0.998 0.000
M86.22 Subacute osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.21 Subacute osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.20 Subacute osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.38 Chronic multifocal osteomyelitis (Other)
0.002 0.998 0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.34 Chronic multifocal osteomyelitis (Hand)
0.002 0.998 0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)
0.002 0.998 0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)
0.002 0.998 0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)
0.002 0.998 0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)
0.002 0.998 0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)
0.002 0.998 0.000
E11.0 With coma
0.002 0.998 0.000
N48.2 Other inflammatory disorders of penis
0.002 0.998 0.000
S02.41 Fracture of malar and maxillary bones (open)
0.002 0.998 0.000
M21.4 Flat foot [pes planus] (acquired)
0.002 0.998 0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand
0.000 0.998 0.002
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group
0.002 0.998 0.000
M21 Other acquired deformities of limbs
0.002 0.998 0.000
S02.71 Multiple fractures involving skull and facial bones (open)
0.002 0.998 0.000
D40.1 Testis
0.002 0.998 0.000
N43 Hydrocele and spermatocele
0.002 0.998 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.998 0.002
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns
0.002 0.998 0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other
0.002 0.998 0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le
0.002 0.998 0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t
0.002 0.998 0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)
0.002 0.998 0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm
0.002 0.998 0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar
0.002 0.998 0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re
0.002 0.998 0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)
0.002 0.998 0.000
M86.87 Other osteomyelitis (Ankle and foot)
0.002 0.998 0.000
E23.2 Diabetes insipidus
0.002 0.998 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.000 0.998 0.002
I70.0 Atherosclerosis of aorta
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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