TreeWAS – Variant ID: rs3756008

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I26.9 Pulmonary embolism without mention of acute cor pulmonale	1.000	0.000	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	1.000	0.000	0.000
Z86.7 Personal history of diseases of the circulatory system	1.000	0.000	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.994	0.006	0.000
I80 Phlebitis and thrombophlebitis	0.772	0.228	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.766	0.234	0.000
I26 Pulmonary embolism	0.681	0.319	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.568	0.432	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.501	0.499	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.487	0.513	0.000
I27 Other pulmonary heart diseases	0.473	0.527	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.436	0.563	0.000
I27.0 Primary pulmonary hypertension	0.432	0.568	0.000
I27.2 Other secondary pulmonary hypertension	0.405	0.595	0.000
I27.9 Pulmonary heart disease, unspecified	0.375	0.625	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.344	0.656	0.000
I27.1 Kyphoscoliotic heart disease	0.339	0.661	0.000
I28 Other diseases of pulmonary vessels	0.311	0.689	0.000
I27.8 Other specified pulmonary heart diseases	0.294	0.706	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.228	0.771	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.224	0.776	0.000
I28.1 Aneurysm of pulmonary artery	0.223	0.777	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.223	0.777	0.000
I28.8 Other specified diseases of pulmonary vessels	0.173	0.827	0.000
I44.2 Atrioventricular block, complete	0.092	0.908	0.000
I44.0 Atrioventricular block, first degree	0.089	0.911	0.000
I44 Atrioventricular and left bundle-branch block	0.082	0.918	0.000
I44.3 Other and unspecified atrioventricular block	0.065	0.935	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.937	0.063
I44.5 Left posterior fascicular block	0.059	0.941	0.000
I44.6 Other and unspecified fascicular block	0.057	0.943	0.000
I44.7 Left bundle-branch block, unspecified	0.045	0.955	0.000
I44.4 Left anterior fascicular block	0.040	0.959	0.000
H73 Other disorders of tympanic membrane	0.000	0.965	0.035
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.967	0.033
Chapter IX Diseases of the circulatory system	0.027	0.973	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.973	0.027
H73.1 Chronic myringitis	0.000	0.974	0.026
I30 Acute pericarditis	0.026	0.974	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.026	0.974	0.000
I30-I52 Other forms of heart disease	0.026	0.974	0.000
I30.9 Acute pericarditis, unspecified	0.026	0.974	0.000
I34.0 Mitral (valve) insufficiency	0.025	0.975	0.000
H73.0 Acute myringitis	0.000	0.975	0.025
I34 Nonrheumatic mitral valve disorders	0.025	0.975	0.000
I31 Other diseases of pericardium	0.023	0.977	0.000
I30.1 Infective pericarditis	0.022	0.978	0.000
I31.9 Disease of pericardium, unspecified	0.021	0.979	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.021	0.979	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.979	0.021
I31.0 Chronic adhesive pericarditis	0.020	0.980	0.000
I00-I02 Acute rheumatic fever	0.020	0.980	0.000
I88 Nonspecific lymphadenitis	0.020	0.980	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.980	0.020
H02.6 Xanthelasma of eyelid	0.000	0.980	0.020
I30.8 Other forms of acute pericarditis	0.020	0.980	0.000
I45.3 Trifascicular block	0.020	0.980	0.000
I45 Other conduction disorders	0.020	0.980	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.019	0.980	0.000
D47.4 Osteomyelofibrosis	0.000	0.981	0.019
I30.0 Acute nonspecific idiopathic pericarditis	0.019	0.981	0.000
M13.94 Arthritis, unspecified (Hand)	0.000	0.981	0.019
I52 Other heart disorders in diseases classified elsewhere	0.019	0.981	0.000
I48 Atrial fibrillation and flutter	0.019	0.981	0.000
I41 Myocarditis in diseases classified elsewhere	0.019	0.981	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.019	0.981	0.000
I32 Pericarditis in diseases classified elsewhere	0.019	0.981	0.000
I44.1 Atrioventricular block, second degree	0.018	0.982	0.000
I45.9 Conduction disorder, unspecified	0.018	0.982	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.018	0.982	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.982	0.018
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.983	0.017
M13.9 Arthritis, unspecified	0.000	0.983	0.017
I40 Acute myocarditis	0.017	0.983	0.000
I31.8 Other specified diseases of pericardium	0.017	0.983	0.000
I31.2 Haemopericardium, not elsewhere classified	0.017	0.983	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.017	0.983	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.983	0.017
I45.5 Other specified heart block	0.016	0.984	0.000
I42 Cardiomyopathy	0.016	0.984	0.000
I00 Rheumatic fever without mention of heart involvement	0.016	0.984	0.000
I42.0 Dilated cardiomyopathy	0.016	0.984	0.000
I05-I09 Chronic rheumatic heart diseases	0.015	0.985	0.000
D47.2 Monoclonal gammopathy	0.000	0.985	0.015
I37 Pulmonary valve disorders	0.015	0.985	0.000
I34.1 Mitral (valve) prolapse	0.015	0.985	0.000
I33 Acute and subacute endocarditis	0.015	0.985	0.000
I31.1 Chronic constrictive pericarditis	0.015	0.985	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.015	0.985	0.000
I02 Rheumatic chorea	0.015	0.985	0.000
I01 Rheumatic fever with heart involvement	0.015	0.985	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.015	0.985	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.985	0.015
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.985	0.015
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.985	0.014
I45.4 Nonspecific intraventricular block	0.014	0.986	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.014	0.986	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.014	0.986	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.014	0.986	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
I46 Cardiac arrest	0.014	0.986	0.000
I88.8 Other nonspecific lymphadenitis	0.014	0.986	0.000
I45.0 Right fascicular block	0.014	0.986	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.014	0.986	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.014	0.986	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.014	0.986	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.014	0.986	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.014	0.986	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.014	0.986	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.014	0.986	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.014	0.986	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.014	0.986	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.014	0.986	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.014	0.986	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.014	0.986	0.000
I48.4 Atypical atrial flutter	0.014	0.986	0.000
I48.3 Typical atrial flutter	0.014	0.986	0.000
I48.2 Chronic atrial fibrillation	0.014	0.986	0.000
I48.1 Persistent atrial fibrillation	0.014	0.986	0.000
I48.0 Paroxysmal atrial fibrillation	0.014	0.986	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.014	0.986	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.014	0.986	0.000
I81 Portal vein thrombosis	0.014	0.986	0.000
I86 Varicose veins of other sites	0.014	0.986	0.000
I45.8 Other specified conduction disorders	0.013	0.986	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.013	0.987	0.000
I36 Nonrheumatic tricuspid valve disorders	0.012	0.987	0.001
I06 Rheumatic aortic valve diseases	0.013	0.987	0.000
I09 Other rheumatic heart diseases	0.013	0.987	0.000
I40.9 Acute myocarditis, unspecified	0.013	0.987	0.000
I85 Oesophageal varices	0.013	0.987	0.000
I40.8 Other acute myocarditis	0.012	0.988	0.000
I40.1 Isolated myocarditis	0.012	0.988	0.000
F52.2 Failure of genital response	0.012	0.988	0.000
D41.0 Kidney	0.000	0.988	0.012
I10-I15 Hypertensive diseases	0.012	0.988	0.000
I51 Complications and ill-defined descriptions of heart disease	0.012	0.988	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.012	0.988	0.000
R82.9 Other and unspecified abnormal finding in urine	0.012	0.988	0.000
I42.5 Other restrictive cardiomyopathy	0.012	0.988	0.000
I42.4 Endocardial fibroelastosis	0.012	0.988	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.012	0.988	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.988	0.012
I42.2 Other hypertrophic cardiomyopathy	0.012	0.988	0.000
I86.1 Scrotal varices	0.011	0.989	0.000
I06.0 Rheumatic aortic stenosis	0.011	0.989	0.000
I82 Other venous embolism and thrombosis	0.011	0.989	0.000
I09.9 Rheumatic heart disease, unspecified	0.011	0.989	0.000
I37.9 Pulmonary valve disorder, unspecified	0.011	0.989	0.000
I37.8 Other pulmonary valve disorders	0.011	0.989	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.011	0.989	0.000
I31.3 Pericardial effusion (noninflammatory)	0.011	0.989	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.011	0.989	0.000
I01.8 Other acute rheumatic heart disease	0.011	0.989	0.000
I01.2 Acute rheumatic myocarditis	0.011	0.989	0.000
I01.1 Acute rheumatic endocarditis	0.011	0.989	0.000
I01.0 Acute rheumatic pericarditis	0.011	0.989	0.000
I02.9 Rheumatic chorea without heart involvement	0.011	0.989	0.000
I02.0 Rheumatic chorea with heart involvement	0.011	0.989	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.989	0.011
I07 Rheumatic tricuspid valve diseases	0.011	0.989	0.000
I37.0 Pulmonary valve stenosis	0.010	0.989	0.000
I51.0 Cardiac septal defect, acquired	0.011	0.989	0.000
Z01.6 Radiological examination, not elsewhere classified	0.011	0.989	0.000
I42.6 Alcoholic cardiomyopathy	0.010	0.989	0.000
I33.9 Acute endocarditis, unspecified	0.010	0.989	0.000
I46.1 Sudden cardiac death, so described	0.010	0.990	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.010	0.990	0.000
I86.0 Sublingual varices	0.010	0.990	0.000
I40.0 Infective myocarditis	0.010	0.990	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.010	0.990	0.000
I51.4 Myocarditis, unspecified	0.010	0.990	0.000
I86.2 Pelvic varices	0.010	0.990	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.990	0.010
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.009	0.990	0.001
I36.8 Other nonrheumatic tricuspid valve disorders	0.009	0.990	0.001
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.009	0.990	0.001
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.009	0.990	0.001
I13 Hypertensive heart and renal disease	0.010	0.990	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.009	0.990	0.000
I06.8 Other rheumatic aortic valve diseases	0.009	0.990	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.009	0.990	0.000
I06.1 Rheumatic aortic insufficiency	0.009	0.990	0.000
I09.8 Other specified rheumatic heart diseases	0.009	0.990	0.000
I09.2 Chronic rheumatic pericarditis	0.009	0.990	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.009	0.990	0.000
I09.0 Rheumatic myocarditis	0.009	0.990	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.990	0.009
I15 Secondary hypertension	0.009	0.990	0.000
Z92 Personal history of medical treatment	0.009	0.991	0.000
I86.3 Vulval varices	0.009	0.991	0.000
I82.0 Budd-Chiari syndrome	0.009	0.991	0.000
D43.2 Brain, unspecified	0.000	0.991	0.009
E10.3 With ophthalmic complications	0.009	0.991	0.000
I46.0 Cardiac arrest with successful resuscitation	0.009	0.991	0.000
I05 Rheumatic mitral valve diseases	0.009	0.991	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.991	0.009
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.991	0.009
I51.2 Rupture of papillary muscle, not elsewhere classified	0.009	0.991	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.991	0.009
I51.5 Myocardial degeneration	0.009	0.991	0.000
I38 Endocarditis, valve unspecified	0.009	0.991	0.000
I51.9 Heart disease, unspecified	0.009	0.991	0.000
I12 Hypertensive renal disease	0.008	0.992	0.000
I82.1 Thrombophlebitis migrans	0.008	0.992	0.000
I05.0 Mitral stenosis	0.008	0.992	0.000
I11 Hypertensive heart disease	0.008	0.992	0.000
I87 Other disorders of veins	0.008	0.992	0.000
I37.1 Pulmonary valve insufficiency	0.008	0.992	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.008	0.992	0.000
I42.9 Cardiomyopathy, unspecified	0.008	0.992	0.000
I33.0 Acute and subacute infective endocarditis	0.008	0.992	0.000
I07.9 Tricuspid valve disease, unspecified	0.008	0.992	0.000
I07.8 Other tricuspid valve diseases	0.008	0.992	0.000
I07.2 Tricuspid stenosis with insufficiency	0.008	0.992	0.000
I07.0 Tricuspid stenosis	0.008	0.992	0.000
I85.0 Oesophageal varices with bleeding	0.008	0.992	0.000
I82.3 Embolism and thrombosis of renal vein	0.008	0.992	0.000
I51.8 Other ill-defined heart diseases	0.008	0.992	0.000
I86.4 Gastric varices	0.008	0.992	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.008	0.992	0.000
I83 Varicose veins of lower extremities	0.008	0.992	0.000
I46.9 Cardiac arrest, unspecified	0.008	0.992	0.000
I51.6 Cardiovascular disease, unspecified	0.008	0.992	0.000
I82.2 Embolism and thrombosis of vena cava	0.008	0.992	0.000
Z92.5 Personal history of rehabilitation measures	0.008	0.992	0.000
I42.8 Other cardiomyopathies	0.007	0.992	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.992	0.008
I15.9 Seconday hypertension, unspecified	0.008	0.992	0.000
I07.1 Tricuspid insufficiency	0.008	0.992	0.000
I15.2 Hypertension secondary to endocrine disorders	0.007	0.993	0.000
I15.0 Renovascular hypertension	0.007	0.993	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.993	0.007
F52 Sexual dysfunction, not caused by organic disorder or disease	0.007	0.993	0.000
E87.6 Hypokalaemia	0.000	0.993	0.007
I12.9 Hypertensive renal disease without renal failure	0.007	0.993	0.000
D43.0 Brain, supratentorial	0.000	0.993	0.007
M13.93 Arthritis, unspecified (Forearm)	0.000	0.993	0.007
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.007	0.993	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.007	0.993	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.007	0.993	0.000
I15.8 Other secondary hypertension	0.007	0.993	0.000
Z92.9 Personal history of medical treatment, unspecified	0.007	0.993	0.000
D44.3 Pituitary gland	0.000	0.993	0.007
D46 Myelodysplastic syndromes	0.000	0.993	0.007
D43.1 Brain, infratentorial	0.000	0.993	0.007
R82 Other abnormal findings in urine	0.007	0.993	0.000
I05.8 Other mitral valve diseases	0.007	0.993	0.000
D43.9 Central nervous system, unspecified	0.000	0.993	0.007
D43.7 Other parts of central nervous system	0.000	0.993	0.007
D43.3 Cranial nerves	0.000	0.993	0.007
D41.9 Urinary organ, unspecified	0.000	0.993	0.007
D41.7 Other urinary organs	0.000	0.993	0.007
D41.3 Urethra	0.000	0.993	0.007
I83.0 Varicose veins of lower extremities with ulcer	0.007	0.993	0.000
D41.2 Ureter	0.000	0.993	0.007
I45.2 Bifascicular block	0.006	0.993	0.001
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.993	0.007
I86.8 Varicose veins of other specified sites	0.006	0.993	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.993	0.007
I82.9 Embolism and thrombosis of unspecified vein	0.006	0.993	0.000
D43.4 Spinal cord	0.000	0.993	0.006
D41.1 Renal pelvis	0.000	0.994	0.006
I11.0 Hypertensive heart disease with (congestive) heart failure	0.006	0.994	0.000
I87.0 Postphlebitic syndrome	0.006	0.994	0.000
D44.4 Craniopharyngeal duct	0.000	0.994	0.006
I15.1 Hypertension secondary to other renal disorders	0.006	0.994	0.000
M13 Other arthritis	0.000	0.994	0.006
D48.7 Other specified sites	0.000	0.994	0.006
I50 Heart failure	0.006	0.994	0.000
D46.4 Refractory anaemia, unspecified	0.000	0.994	0.006
I95-I99 Other and unspecified disorders of the circulatory system	0.006	0.994	0.000
D48.1 Connective and other soft tissue	0.000	0.994	0.006
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.006	0.994	0.000
I87.9 Disorder of vein, unspecified	0.006	0.994	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.006	0.994	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.994	0.006
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.994	0.006
D46.1 Refractory anaemia with sideroblasts	0.000	0.994	0.006
R82.4 Acetonuria	0.006	0.994	0.000
F52.0 Lack or loss of sexual desire	0.006	0.994	0.000
D44.8 Pluriglandular involvement	0.000	0.994	0.006
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.994	0.006
H65-H75 Diseases of middle ear and mastoid	0.000	0.994	0.006
D46.2 Refractory anaemia with excess of blasts	0.000	0.994	0.006
D48.0 Bone and articular cartilage	0.000	0.994	0.006
D44.9 Endocrine gland, unspecified	0.000	0.994	0.005
D44.5 Pineal gland	0.000	0.994	0.005
D44.2 Parathyroid gland	0.000	0.994	0.005
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.005	0.994	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.005	0.994	0.000
F52.7 Excessive sexual drive	0.005	0.994	0.000
F52.6 Nonorganic dyspareunia	0.005	0.994	0.000
F52.5 Nonorganic vaginismus	0.005	0.994	0.000
F52.4 Premature ejaculation	0.005	0.994	0.000
F52.3 Orgasmic dysfunction	0.005	0.994	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.005	0.994	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.005	0.994	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.995	0.005
E83.3 Disorders of phosphorus metabolism	0.000	0.995	0.005
D48.4 Peritoneum	0.000	0.995	0.005
Z92.8 Personal history of other medical treatment	0.005	0.995	0.000
D44.0 Thyroid gland	0.000	0.995	0.005
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.995	0.005
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.995	0.005
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.995	0.005
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.995	0.005
H71 Cholesteatoma of middle ear	0.000	0.995	0.005
D44.7 Aortic body and other paraganglia	0.000	0.995	0.005
I85.9 Oesophageal varices without bleeding	0.005	0.995	0.000
S81.9 Open wound of lower leg, part unspecified	0.005	0.995	0.000
D38.1 Trachea, bronchus and lung	0.000	0.995	0.005
I05.9 Mitral valve disease, unspecified	0.005	0.995	0.000
H02.8 Other specified disorders of eyelid	0.000	0.995	0.005
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
R82.3 Haemoglobinuria	0.005	0.995	0.000
R82.2 Biliuria	0.005	0.995	0.000
R82.0 Chyluria	0.005	0.995	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.005	0.995	0.000
D44.6 Carotid body	0.000	0.995	0.005
I87.8 Other specified disorders of veins	0.005	0.995	0.000
D42.9 Meninges, unspecified	0.000	0.995	0.005
D42.1 Spinal meninges	0.000	0.995	0.005
D42.0 Cerebral meninges	0.000	0.995	0.005
D48.3 Retroperitoneum	0.000	0.995	0.005
R82.1 Myoglobinuria	0.005	0.995	0.000
I05.2 Mitral stenosis with insufficiency	0.005	0.995	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.995	0.005
I50.9 Heart failure, unspecified	0.005	0.995	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.995	0.005
I05.1 Rheumatic mitral insufficiency	0.005	0.995	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.995	0.005
N02.8 Other	0.005	0.995	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.995	0.005
M13.8 Other specified arthritis	0.000	0.995	0.005
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.005	0.995	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.995	0.005
S81.7 Multiple open wounds of lower leg	0.005	0.995	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.995	0.005
C43.5 Malignant melanoma of trunk	0.005	0.995	0.000
M13.1 Monoarthritis, not elsewhere classified	0.000	0.995	0.004
D38.6 Respiratory organ, unspecified	0.000	0.995	0.004
D38.4 Thymus	0.000	0.995	0.004
D38.2 Pleura	0.000	0.995	0.004
D46.7 Other myelodysplastic syndromes	0.000	0.995	0.004
D40.9 Male genital organ, unspecified	0.000	0.996	0.004
D40.7 Other male genital organs	0.000	0.996	0.004
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.003	0.996	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.996	0.004
H68 Eustachian salpingitis and obstruction	0.000	0.996	0.004
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.996	0.004
H67 Otitis media in diseases classified elsewhere	0.000	0.996	0.004
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
I87.2 Venous insufficiency (chronic) (peripheral)	0.004	0.996	0.000
H02 Other disorders of eyelid	0.000	0.996	0.004
D40.0 Prostate	0.000	0.996	0.004
E83.4 Disorders of magnesium metabolism	0.000	0.996	0.004
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.996	0.004
D44.1 Adrenal gland	0.000	0.996	0.004
M06.4 Inflammatory polyarthropathy	0.000	0.996	0.004
M06 Other rheumatoid arthritis	0.000	0.996	0.004
Z47.8 Other specified orthopaedic follow-up care	0.004	0.996	0.000
I45.6 Preexcitation syndrome	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.000	0.996	0.004
D38.5 Other respiratory organs	0.000	0.996	0.004
D38.3 Mediastinum	0.000	0.996	0.004
S81 Open wound of lower leg	0.004	0.996	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.996	0.004
H74.4 Polyp of middle ear	0.000	0.996	0.004
M06.0 Seronegative rheumatoid arthritis	0.000	0.996	0.004
E83 Disorders of mineral metabolism	0.000	0.996	0.004
D38.0 Larynx	0.000	0.996	0.004
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.996	0.004
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
H74.1 Adhesive middle ear disease	0.000	0.996	0.004
M13.80 Other specified arthritis (Multiple sites)	0.000	0.996	0.004
S81.0 Open wound of knee	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.004	0.996	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.996	0.004
D39.9 Female genital organ, unspecified	0.000	0.996	0.004
D39.2 Placenta	0.000	0.996	0.004
D40.1 Testis	0.000	0.996	0.004
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
H70 Mastoiditis and related conditions	0.000	0.996	0.004
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.996	0.004
H65.0 Acute serous otitis media	0.000	0.996	0.004
M21.26 Flexion deformity (Lower leg)	0.004	0.996	0.000
I87.1 Compression of vein	0.003	0.996	0.000
M13.88 Other specified arthritis (Other)	0.000	0.996	0.003
M13.87 Other specified arthritis (Ankle and foot)	0.000	0.996	0.003
M13.85 Other specified arthritis (Pelvic region and thigh)	0.000	0.996	0.003
M13.84 Other specified arthritis (Hand)	0.000	0.996	0.003
M13.83 Other specified arthritis (Forearm)	0.000	0.996	0.003
M13.82 Other specified arthritis (Upper arm)	0.000	0.996	0.003
M13.81 Other specified arthritis (Shoulder region)	0.000	0.996	0.003
D66 Hereditary factor VIII deficiency	0.000	0.996	0.004
D39.7 Other female genital organs	0.000	0.996	0.003
M13.86 Other specified arthritis (Lower leg)	0.000	0.996	0.003
K22.0 Achalasia of cardia	0.000	0.996	0.004
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.000	0.996	0.003
M13.18 Monoarthritis, not elsewhere classified (Other)	0.000	0.996	0.003
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.000	0.996	0.003
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.003
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.000	0.996	0.003
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.000	0.996	0.003
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.000	0.996	0.003
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.000	0.996	0.003
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.000	0.996	0.003
M21.27 Flexion deformity (Ankle and foot)	0.004	0.996	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.996	0.004
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.996	0.003
D39.0 Uterus	0.000	0.996	0.003
M13.89 Other specified arthritis (Site unspecified)	0.000	0.997	0.003
H65.2 Chronic serous otitis media	0.000	0.997	0.003
H68.1 Obstruction of Eustachian tube	0.000	0.997	0.003
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.997	0.003
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.000	0.997	0.003
H68.0 Eustachian salpingitis	0.000	0.997	0.003
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.997	0.003
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.997	0.003
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.997	0.003
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.997	0.003
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.003
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.997	0.003
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.000	0.997	0.003
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.003
E83.5 Disorders of calcium metabolism	0.000	0.997	0.003
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.997	0.003
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.997	0.003
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.997	0.003
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.997	0.003
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.997	0.003
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.997	0.003
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.997	0.003
M06.2 Rheumatoid bursitis	0.000	0.997	0.003
M06.1 Adult-onset Still's disease	0.000	0.997	0.003
I35 Nonrheumatic aortic valve disorders	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.997	0.003
H02.5 Other disorders affecting eyelid function	0.000	0.997	0.003
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.997	0.003
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.997	0.003
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.997	0.003
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.997	0.003
M13.98 Arthritis, unspecified (Other)	0.001	0.997	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.997	0.003
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.997	0.003
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.997	0.003
E83.8 Other disorders of mineral metabolism	0.000	0.997	0.003
E83.2 Disorders of zinc metabolism	0.000	0.997	0.003
E83.0 Disorders of copper metabolism	0.000	0.997	0.003
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.003	0.997	0.000
I95 Hypotension	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.003
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.997	0.003
I97.9 Postprocedural disorder of circulatory system, unspecified	0.003	0.997	0.000
I97.0 Postcardiotomy syndrome	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.000	0.997	0.003
H02.0 Entropion and trichiasis of eyelid	0.000	0.997	0.003
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.997	0.003
H70.2 Petrositis	0.000	0.997	0.003
R82.8 Abnormal findings on cytological and histological examination of urine	0.003	0.997	0.000
G54.0 Brachial plexus disorders	0.003	0.997	0.000
W55.8 Other specified place	0.003	0.997	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.003	0.997	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
D39.1 Ovary	0.000	0.997	0.003
I97.1 Other functional disturbances following cardiac surgery	0.003	0.997	0.000
D48.6 Breast	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.997	0.003
E10.0 With coma	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.000	0.997	0.003
M06.8 Other specified rheumatoid arthritis	0.000	0.997	0.003
M21.2 Flexion deformity	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.997	0.003
Q38.7 Pharyngeal pouch	0.000	0.997	0.003
H69 Other disorders of Eustachian tube	0.000	0.997	0.003
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.003	0.997	0.000
Z92.0 Personal history of contraception	0.002	0.997	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.000	0.997	0.003
I95.0 Idiopathic hypotension	0.003	0.997	0.000
F51 Nonorganic sleep disorders	0.003	0.997	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I98.0 Cardiovascular syphilis	0.003	0.997	0.000
M06.3 Rheumatoid nodule	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations