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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3757340
log Bayes Factor = 37.7898
Chromosome 6   position 30,921,882  (GRCh37) Explore rs3757340 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
0.992 0.008 0.000
E04 Other non-toxic goitre
0.000 0.090 0.910
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.098 0.902
E50-E64 Other nutritional deficiencies
0.000 0.105 0.895
E53 Deficiency of other B group vitamins
0.000 0.110 0.890
E53.8 Deficiency of other specified B group vitamins
0.000 0.115 0.885
E10-E14 Diabetes mellitus
0.000 0.145 0.855
E10 Insulin-dependent diabetes mellitus
0.000 0.147 0.853
E10.9 Without complications
0.000 0.172 0.828
E10.5 With peripheral circulatory complications
0.000 0.182 0.818
E04.2 Non-toxic multinodular goitre
0.000 0.188 0.812
L40.8 Other psoriasis
0.812 0.188 0.000
L40.4 Guttate psoriasis
0.799 0.201 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.205 0.795
E07 Other disorders of thyroid
0.000 0.211 0.789
L40.1 Generalised pustular psoriasis
0.787 0.213 0.000
E10.4 With neurological complications
0.000 0.221 0.779
E06 Thyroiditis
0.000 0.233 0.767
E04.0 Non-toxic diffuse goitre
0.000 0.244 0.755
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.255 0.744
E55 Vitamin D deficiency
0.000 0.256 0.744
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.263 0.737
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.715 0.285 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.287 0.713
E53.9 Vitamin B deficiency, unspecified
0.000 0.296 0.703
E03.1 Congenital hypothyroidism without goitre
0.000 0.326 0.674
E58 Dietary calcium deficiency
0.000 0.342 0.658
E04.8 Other specified non-toxic goitre
0.000 0.348 0.652
E06.3 Autoimmune thyroiditis
0.000 0.351 0.649
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.358 0.642
E63 Other nutritional deficiencies
0.000 0.358 0.642
E51 Thiamine deficiency
0.000 0.358 0.642
E50 Vitamin A deficiency
0.000 0.358 0.642
E60 Dietary zinc deficiency
0.000 0.358 0.642
E59 Dietary selenium deficiency
0.000 0.358 0.642
E54 Ascorbic acid deficiency
0.000 0.358 0.642
E52 Niacin deficiency [pellagra]
0.000 0.358 0.642
E53.1 Pyridoxine deficiency
0.000 0.362 0.638
E53.0 Riboflavin deficiency
0.000 0.362 0.638
E55.9 Vitamin D deficiency, unspecified
0.000 0.365 0.635
E10.2 With renal complications
0.000 0.370 0.630
E07.9 Disorder of thyroid, unspecified
0.000 0.371 0.629
E10.6 With other specified complications
0.000 0.380 0.620
E56 Other vitamin deficiencies
0.000 0.383 0.616
E12 Malnutrition-related diabetes mellitus
0.000 0.387 0.613
E10.7 With multiple complications
0.000 0.388 0.611
E10.0 With coma
0.000 0.389 0.611
E03.8 Other specified hypothyroidism
0.000 0.394 0.605
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.416 0.584
E07.8 Other specified disorders of thyroid
0.000 0.422 0.578
E10.3 With ophthalmic complications
0.000 0.431 0.569
E07.1 Dyshormogenetic goitre
0.000 0.434 0.565
E07.0 Hypersecretion of calcitonin
0.000 0.434 0.565
E05.8 Other thyrotoxicosis
0.000 0.441 0.559
E06.4 Drug-induced thyroiditis
0.000 0.450 0.550
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.450 0.550
E06.0 Acute thyroiditis
0.000 0.450 0.550
E13 Other specified diabetes mellitus
0.000 0.454 0.546
E06.9 Thyroiditis, unspecified
0.000 0.457 0.542
E06.5 Other chronic thyroiditis
0.000 0.458 0.541
E55.0 Rickets, active
0.000 0.467 0.533
E20-E35 Disorders of other endocrine glands
0.000 0.468 0.532
E65-E68 Obesity and other hyperalimentation
0.000 0.474 0.526
E10.8 With unspecified complications
0.000 0.478 0.522
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E61 Deficiency of other nutrient elements
0.000 0.492 0.508
E27 Other disorders of adrenal gland
0.000 0.505 0.495
K90 Intestinal malabsorption
0.000 0.505 0.495
E40-E46 Malnutrition
0.000 0.507 0.493
E27.1 Primary adrenocortical insufficiency
0.000 0.508 0.492
E06.1 Subacute thyroiditis
0.000 0.516 0.484
E50.9 Vitamin A deficiency, unspecified
0.000 0.540 0.460
E50.8 Other manifestations of vitamin A deficiency
0.000 0.540 0.460
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.540 0.460
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.540 0.460
E50.5 Vitamin A deficiency with night blindness
0.000 0.540 0.460
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.540 0.460
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.540 0.460
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.540 0.460
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.540 0.460
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.540 0.460
E51.9 Thiamine deficiency, unspecified
0.000 0.540 0.460
E51.8 Other manifestations of thiamine deficiency
0.000 0.540 0.460
E51.2 Wernicke's encephalopathy
0.000 0.540 0.460
E51.1 Beriberi
0.000 0.540 0.460
E63.9 Nutritional deficiency, unspecified
0.000 0.540 0.460
E63.8 Other specified nutritional deficiencies
0.000 0.540 0.460
E63.1 Imbalance of constituents of food intake
0.000 0.540 0.460
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.540 0.460
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.540 0.460
E64.8 Sequelae of other nutritional deficiencies
0.000 0.540 0.460
E64.3 Sequelae of rickets
0.000 0.540 0.460
E64.2 Sequelae of vitamin C deficiency
0.000 0.540 0.460
E64.1 Sequelae of vitamin A deficiency
0.000 0.540 0.460
E64.0 Sequelae of protein-energy malnutrition
0.000 0.540 0.460
E10.1 With ketoacidosis
0.000 0.541 0.459
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.548 0.452
E56.9 Vitamin deficiency, unspecified
0.000 0.558 0.442
E56.8 Deficiency of other vitamins
0.000 0.558 0.442
E56.0 Deficiency of vitamin E
0.000 0.558 0.442
E12.9 Without complications
0.000 0.560 0.439
E12.8 With unspecified complications
0.000 0.560 0.439
E12.7 With multiple complications
0.000 0.560 0.439
E12.6 With other specified complications
0.000 0.560 0.439
E12.5 With peripheral circulatory complications
0.000 0.560 0.439
E12.4 With neurological complications
0.000 0.560 0.439
E12.3 With ophthalmic complications
0.000 0.560 0.439
E12.2 With renal complications
0.000 0.560 0.439
E12.1 With ketoacidosis
0.000 0.560 0.439
E12.0 With coma
0.000 0.560 0.439
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.567 0.433
E15 Nondiabetic hypoglycaemic coma
0.000 0.581 0.419
E21.3 Hyperparathyroidism, unspecified
0.000 0.583 0.417
E56.1 Deficiency of vitamin K
0.000 0.583 0.417
E34 Other endocrine disorders
0.000 0.604 0.396
E27.2 Addisonian crisis
0.000 0.606 0.394
E13.8 With unspecified complications
0.000 0.609 0.391
E13.7 With multiple complications
0.000 0.609 0.391
E13.6 With other specified complications
0.000 0.609 0.391
E13.5 With peripheral circulatory complications
0.000 0.609 0.391
E13.4 With neurological complications
0.000 0.609 0.391
E13.3 With ophthalmic complications
0.000 0.609 0.391
E13.2 With renal complications
0.000 0.609 0.391
E13.1 With ketoacidosis
0.000 0.609 0.391
E13.0 With coma
0.000 0.609 0.391
E20 Hypoparathyroidism
0.000 0.615 0.385
E65 Localised adiposity
0.000 0.618 0.382
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.618 0.381
E32 Diseases of thymus
0.000 0.618 0.381
E31 Polyglandular dysfunction
0.000 0.618 0.381
E30 Disorders of puberty, not elsewhere classified
0.000 0.618 0.381
E21.0 Primary hyperparathyroidism
0.000 0.618 0.382
E67 Other hyperalimentation
0.000 0.623 0.377
E68 Sequelae of hyperalimentation
0.000 0.623 0.377
E28 Ovarian dysfunction
0.000 0.632 0.368
E61.9 Deficiency of nutrient element, unspecified
0.000 0.636 0.364
E61.8 Deficiency of other specified nutrient elements
0.000 0.636 0.364
E61.7 Deficiency of multiple nutrient elements
0.000 0.636 0.364
E61.6 Vanadium deficiency
0.000 0.636 0.364
E61.5 Molybdenum deficiency
0.000 0.636 0.364
E61.4 Chromium deficiency
0.000 0.636 0.364
E61.3 Manganese deficiency
0.000 0.636 0.364
E61.0 Copper deficiency
0.000 0.636 0.364
E16 Other disorders of pancreatic internal secretion
0.000 0.644 0.356
E27.5 Adrenomedullary hyperfunction
0.000 0.645 0.355
E27.0 Other adrenocortical overactivity
0.000 0.645 0.355
K90.3 Pancreatic steatorrhoea
0.000 0.645 0.355
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.645 0.355
K90.1 Tropical sprue
0.000 0.645 0.355
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.646 0.354
E45 Retarded development following protein-energy malnutrition
0.000 0.646 0.354
E43 Unspecified severe protein-energy malnutrition
0.000 0.646 0.354
E42 Marasmic kwashiorkor
0.000 0.646 0.354
E41 Nutritional marasmus
0.000 0.646 0.354
E40 Kwashiorkor
0.000 0.646 0.354
E14 Unspecified diabetes mellitus
0.000 0.648 0.352
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.347 0.653 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.657 0.343
T36-T50 Poisoning by drugs, medicaments and biological substances
0.341 0.659 0.000
E26 Hyperaldosteronism
0.000 0.662 0.337
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.333 0.667 0.000
E22 Hyperfunction of pituitary gland
0.000 0.672 0.328
T43.0 Tricyclic and tetracyclic antidepressants
0.327 0.673 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.675 0.325
E21.2 Other hyperparathyroidism
0.000 0.676 0.324
E13.9 Without complications
0.000 0.676 0.324
E61.2 Magnesium deficiency
0.000 0.678 0.322
T46 Poisoning by agents primarily affecting the cardiovascular system
0.321 0.679 0.000
L40-L45 Papulosquamous disorders
0.321 0.679 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.680 0.320
T43.2 Other and unspecified antidepressants
0.320 0.680 0.000
E25 Adrenogenital disorders
0.000 0.680 0.319
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.314 0.686 0.000
T43.6 Psychostimulants with abuse potential
0.313 0.687 0.000
E29 Testicular dysfunction
0.000 0.690 0.310
E34.8 Other specified endocrine disorders
0.000 0.691 0.309
E34.9 Endocrine disorder, unspecified
0.000 0.698 0.302
T43.4 Butyrophenone and thioxanthene neuroleptics
0.302 0.698 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.700 0.300
K90.8 Other intestinal malabsorption
0.000 0.701 0.299
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.299 0.701 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.296 0.704 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.295 0.705 0.000
E61.1 Iron deficiency
0.000 0.706 0.293
E28.3 Primary ovarian failure
0.000 0.707 0.293
E34.5 Androgen resistance syndrome
0.000 0.716 0.284
E34.4 Constitutional tall stature
0.000 0.716 0.284
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.716 0.284
E34.1 Other hypersecretion of intestinal hormones
0.000 0.716 0.284
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.282 0.718 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.721 0.279
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.721 0.278
E20.8 Other hypoparathyroidism
0.000 0.724 0.276
E20.1 Pseudohypoparathyroidism
0.000 0.724 0.276
E20.0 Idiopathic hypoparathyroidism
0.000 0.724 0.276
E14.8 With unspecified complications
0.000 0.726 0.274
E30.9 Disorder of puberty, unspecified
0.000 0.726 0.274
E30.8 Other disorders of puberty
0.000 0.726 0.274
E30.1 Precocious puberty
0.000 0.726 0.274
E30.0 Delayed puberty
0.000 0.726 0.274
E31.9 Polyglandular dysfunction, unspecified
0.000 0.726 0.274
E31.8 Other polyglandular dysfunction
0.000 0.726 0.274
E31.1 Polyglandular hyperfunction
0.000 0.726 0.274
E31.0 Autoimmune polyglandular failure
0.000 0.726 0.274
E32.9 Disease of thymus, unspecified
0.000 0.726 0.274
E32.8 Other diseases of thymus
0.000 0.726 0.274
E32.1 Abscess of thymus
0.000 0.726 0.274
E32.0 Persistent hyperplasia of thymus
0.000 0.726 0.274
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.726 0.274
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.726 0.274
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.726 0.274
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.272 0.728 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.729 0.271
E67.8 Other specified hyperalimentation
0.000 0.729 0.270
E67.3 Hypervitaminosis D
0.000 0.729 0.270
E67.2 Megavitamin-B6 syndrome
0.000 0.729 0.270
E67.1 Hypercarotenaemia
0.000 0.729 0.270
E67.0 Hypervitaminosis A
0.000 0.729 0.270
E21.4 Other specified disorders of parathyroid gland
0.000 0.729 0.270
M35 Other systemic involvement of connective tissue
0.000 0.730 0.270
E04.1 Non-toxic single thyroid nodule
0.000 0.731 0.268
E34.3 Short stature, not elsewhere classified
0.000 0.732 0.267
E34.0 Carcinoid syndrome
0.000 0.734 0.266
E28.9 Ovarian dysfunction, unspecified
0.000 0.736 0.264
E28.8 Other ovarian dysfunction
0.000 0.736 0.264
E28.1 Androgen excess
0.000 0.736 0.264
E28.0 Oestrogen excess
0.000 0.736 0.264
E14.5 With peripheral circulatory complications
0.000 0.736 0.264
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.260 0.739 0.000
E14.3 With ophthalmic complications
0.000 0.740 0.260
E14.6 With other specified complications
0.000 0.741 0.259
T46.5 Other antihypertensive drugs, not elsewhere classified
0.259 0.741 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.259 0.741 0.000
L42 Pityriasis rosea
0.258 0.742 0.000
T46.1 Calcium-channel blockers
0.258 0.742 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.744 0.255
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.744 0.255
E16.4 Abnormal secretion of gastrin
0.000 0.744 0.255
E16.3 Increased secretion of glucagon
0.000 0.744 0.255
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.745 0.255
E14.1 With ketoacidosis
0.000 0.745 0.254
E44.1 Mild protein-energy malnutrition
0.000 0.746 0.254
E44.0 Moderate protein-energy malnutrition
0.000 0.746 0.254
E23 Hypofunction and other disorders of pituitary gland
0.000 0.746 0.253
E22.1 Hyperprolactinaemia
0.000 0.747 0.253
E14.7 With multiple complications
0.000 0.747 0.252
E14.0 With coma
0.000 0.747 0.252
T47.4 Other laxatives
0.252 0.748 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.252 0.748 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.251 0.748 0.000
T43.9 Psychotropic drug, unspecified
0.249 0.751 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.249 0.751 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.249 0.751 0.000
E66 Obesity
0.000 0.753 0.247
T41 Poisoning by anaesthetics and therapeutic gases
0.244 0.756 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.244 0.756 0.000
M35.3 Polymyalgia rheumatica
0.000 0.757 0.243
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.243 0.757 0.000
E26.8 Other hyperaldosteronism
0.000 0.758 0.242
E26.1 Secondary hyperaldosteronism
0.000 0.758 0.242
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.239 0.761 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.239 0.761 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.239 0.761 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.239 0.761 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.239 0.761 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.239 0.761 0.000
T44.0 Anticholinesterase agents
0.239 0.761 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.238 0.762 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.237 0.763 0.000
T36 Poisoning by systemic antibiotics
0.236 0.764 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.765 0.235
E22.8 Other hyperfunction of pituitary gland
0.000 0.765 0.235
E26.9 Hyperaldosteronism, unspecified
0.000 0.766 0.234
E14.2 Withrenal complications
0.000 0.767 0.233
T43.3 Phenothiazine antipsychotics and neuroleptics
0.231 0.769 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.231 0.769 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.231 0.769 0.000
T46.7 Peripheral vasodilators
0.231 0.769 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.231 0.769 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.231 0.769 0.000
L44 Other papulosquamous disorders
0.230 0.770 0.000
L41 Parapsoriasis
0.230 0.770 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.230 0.770 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.771 0.229
E25.8 Other adrenogenital disorders
0.000 0.771 0.229
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.771 0.229
T47.1 Other antacids and anti-gastric-secretion drugs
0.228 0.772 0.000
M35.1 Other overlap syndromes
0.000 0.773 0.227
M35.7 Hypermobility syndrome
0.000 0.775 0.225
T45.0 Antiallergic and antiemetic drugs
0.225 0.775 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.225 0.775 0.000
T47.2 Stimulant laxatives
0.223 0.777 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.777 0.222
E29.8 Other testicular dysfunction
0.000 0.777 0.222
E29.0 Testicular hyperfunction
0.000 0.777 0.222
T48.5 Anti-common-cold drugs
0.222 0.777 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.221 0.779 0.000
E24 Cushing's syndrome
0.001 0.779 0.220
E16.2 Hypoglycaemia, unspecified
0.000 0.785 0.215
T46.3 Coronary vasodilators, not elsewhere classified
0.214 0.786 0.000
E66.8 Other obesity
0.000 0.787 0.213
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.213 0.787 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.213 0.787 0.000
T47.7 Emetics
0.213 0.787 0.000
T47.6 Antidiarrhoeal drugs
0.213 0.787 0.000
T47.5 Digestants
0.213 0.787 0.000
T47.3 Saline and osmotic laxatives
0.213 0.787 0.000
T47.0 Histamine H(2)-receptor antagonists
0.213 0.787 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.209 0.790 0.000
E26.0 Primary hyperaldosteronism
0.000 0.790 0.209
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.208 0.792 0.000
E16.1 Other hypoglycaemia
0.000 0.795 0.205
E28.2 Polycystic ovarian syndrome
0.000 0.795 0.205
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.204 0.796 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.203 0.797 0.000
T50.7 Analeptics and opioid receptor antagonists
0.202 0.798 0.000
T50.5 Appetite depressants
0.202 0.798 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.202 0.798 0.000
T50.1 Loop [high-ceiling] diuretics
0.202 0.798 0.000
T50.0 Mineralocorticoids and their antagonists
0.202 0.798 0.000
T50.8 Diagnostic agents
0.201 0.799 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.200 0.800 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.800 0.200
E46 Unspecified protein-energy malnutrition
0.000 0.800 0.200
E22.0 Acromegaly and pituitary gigantism
0.000 0.804 0.196
E27.9 Disorder of adrenal gland, unspecified
0.001 0.804 0.195
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.195 0.805 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.195 0.805 0.000
T48.4 Expectorants
0.195 0.805 0.000
T48.3 Antitussives
0.195 0.805 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.195 0.805 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.195 0.805 0.000
T48.0 Oxytocic drugs
0.195 0.805 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.195 0.805 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.806 0.194
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.806 0.194
M35.5 Multifocal fibrosclerosis
0.000 0.806 0.194
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.806 0.194
M35.2 Behcet's disease
0.000 0.808 0.192
T49.9 Topical agent, unspecified
0.187 0.813 0.000
T49.8 Other topical agents
0.187 0.813 0.000
T49.7 Dental drugs, topically applied
0.187 0.813 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.187 0.813 0.000
T49.5 Ophthalmological drugs and preparations
0.187 0.813 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.187 0.813 0.000
T49.3 Emollients, demulcents and protectants
0.187 0.813 0.000
T49.2 Local astringents and local detergents
0.187 0.813 0.000
T49.1 Antipruritics
0.187 0.813 0.000
T42.3 Barbiturates
0.187 0.813 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.818 0.182
E23.1 Drug-induced hypopituitarism
0.000 0.818 0.182
T38.9 Other and unspecified hormone antagonists
0.180 0.819 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.180 0.819 0.000
T38.7 Androgens and anabolic congeners
0.180 0.819 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.180 0.819 0.000
T38.5 Other oestrogens and progestogens
0.180 0.819 0.000
T38.4 Oral contraceptives
0.180 0.819 0.000
T38.2 Antithyroid drugs
0.180 0.819 0.000
T38.0 Glucocorticoids and synthetic analogues
0.180 0.819 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.180 0.819 0.000
T45.8 Other primarily systemic and haematological agents
0.180 0.819 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.180 0.819 0.000
T45.6 Fibrinolysis-affecting drugs
0.180 0.819 0.000
T45.4 Iron and its compounds
0.180 0.819 0.000
T45.3 Enzymes, not elsewhere classified
0.180 0.819 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.821 0.179
E66.1 Drug-induced obesity
0.000 0.823 0.177
E14.4 With neurological complications
0.000 0.824 0.175
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.175 0.825 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.175 0.825 0.000
T37.5 Antiviral drugs
0.175 0.825 0.000
T37.4 Anthelminthics
0.175 0.825 0.000
T37.3 Other antiprotozoal drugs
0.175 0.825 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.175 0.825 0.000
T37.1 Antimycobacterial drugs
0.175 0.825 0.000
T37.0 Sulphonamides
0.175 0.825 0.000
T41.5 Therapeutic gases
0.175 0.825 0.000
T41.4 Anaesthetic, unspecified
0.175 0.825 0.000
T41.3 Local anaesthetics
0.175 0.825 0.000
T41.2 Other and unspecified general anaesthetics
0.175 0.825 0.000
T41.1 Intravenous anaesthetics
0.175 0.825 0.000
T41.0 Inhaled anaesthetics
0.175 0.825 0.000
T50.4 Drugs affecting uric acid metabolism
0.174 0.825 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.174 0.826 0.000
T42.2 Succinimides and oxazolidinediones
0.174 0.826 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.826 0.174
T36.9 Systemic antibiotic, unspecified
0.169 0.830 0.000
T36.8 Other systemic antibiotics
0.169 0.830 0.000
T36.7 Antifungal antibiotics, systemically used
0.169 0.830 0.000
T36.6 Rifamycins
0.169 0.830 0.000
T36.5 Aminoglycosides
0.169 0.830 0.000
T36.4 Tetracyclines
0.169 0.830 0.000
T36.3 Macrolides
0.169 0.830 0.000
T36.2 Chloramphenicol group
0.169 0.830 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.169 0.830 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.832 0.167
L41.9 Parapsoriasis, unspecified
0.165 0.835 0.000
L41.8 Other parapsoriasis
0.165 0.835 0.000
L41.5 Retiform parapsoriasis
0.165 0.835 0.000
L41.4 Large plaque parapsoriasis
0.165 0.835 0.000
L41.3 Small plaque parapsoriasis
0.165 0.835 0.000
L41.2 Lymphomatoid papulosis
0.165 0.835 0.000
L41.1 Pityriasis lichenoides chronica
0.165 0.835 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.165 0.835 0.000
L44.9 Papulosquamous disorder, unspecified
0.165 0.835 0.000
L44.8 Other specified papulosquamous disorders
0.165 0.835 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.165 0.835 0.000
L44.3 Lichen ruber moniliformis
0.165 0.835 0.000
L44.2 Lichen striatus
0.165 0.835 0.000
L44.1 Lichen nitidus
0.165 0.835 0.000
L44.0 Pityriasis rubra pilaris
0.165 0.835 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.163 0.837 0.000
T36.0 Penicillins
0.161 0.838 0.000
T45.2 Vitamins, not elsewhere classified
0.160 0.839 0.000
E24.8 Other Cushing's syndrome
0.001 0.842 0.158
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.842 0.158
E24.3 Ectopic ACTH syndrome
0.001 0.842 0.158
E24.1 Nelson's syndrome
0.001 0.842 0.158
E23.6 Other disorders of pituitary gland
0.000 0.842 0.158
T38.1 Thyroid hormones and substitutes
0.157 0.843 0.000
E66.0 Obesity due to excess calories
0.000 0.844 0.156
E23.2 Diabetes insipidus
0.000 0.844 0.156
E23.0 Hypopituitarism
0.000 0.845 0.155
T42.1 Iminostilbenes
0.153 0.846 0.000
E29.1 Testicular hypofunction
0.000 0.849 0.151
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.856 0.144
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.861 0.139
E24.2 Drug-induced Cushing's syndrome
0.001 0.863 0.136
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.136 0.864 0.000
T42.0 Hydantoin derivatives
0.134 0.866 0.000
T42.4 Benzodiazepines
0.132 0.868 0.000
E24.0 Pituitary-dependent Cushing's disease
0.001 0.877 0.123
L43 Lichen planus
0.121 0.879 0.000
E24.9 Cushing's syndrome, unspecified
0.001 0.885 0.114
T39.0 Salicylates
0.114 0.886 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.107 0.892 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.098 0.902 0.000
T39.4 Antirheumatics, not elsewhere classified
0.098 0.902 0.000
T39.2 Pyrazolone derivatives
0.098 0.902 0.000
T39.1 4-Aminophenol derivatives
0.091 0.909 0.000
E70-E90 Metabolic disorders
0.000 0.910 0.090
L43.3 Subacute (active) lichen planus
0.087 0.913 0.000
L43.2 Lichenoid drug reaction
0.087 0.913 0.000
L43.1 Bullous lichen planus
0.087 0.913 0.000
L43.0 Hypertrophic lichen planus
0.087 0.913 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.914 0.086
T45.5 Anticoagulants
0.085 0.914 0.001
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.914 0.086
E89.0 Postprocedural hypothyroidism
0.000 0.917 0.083
M06.9 Rheumatoid arthritis, unspecified
0.000 0.919 0.081
E73 Lactose intolerance
0.000 0.923 0.077
M07.30 Other psoriatic arthropathies (Multiple sites)
0.077 0.923 0.000
T40.5 Cocaine
0.076 0.924 0.000
M07.3 Other psoriatic arthropathies
0.074 0.926 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.926 0.074
L43.8 Other lichen planus
0.073 0.926 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.928 0.072
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.071 0.929 0.000
T40.8 Lysergide [LSD]
0.071 0.929 0.000
T40.7 Cannabis (derivatives)
0.071 0.929 0.000
T40.3 Methadone
0.071 0.929 0.000
T40.1 Heroin
0.071 0.929 0.000
T40.0 Opium
0.071 0.929 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.930 0.070
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.931 0.069
E73.9 Lactose intolerance, unspecified
0.000 0.931 0.069
E88 Other metabolic disorders
0.000 0.932 0.068
E89.4 Postprocedural ovarian failure
0.000 0.933 0.067
E84 Cystic fibrosis
0.000 0.933 0.067
E89.2 Postprocedural hypoparathyroidism
0.000 0.933 0.067
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.933 0.067
M07.39 Other psoriatic arthropathies (Site unspecified)
0.066 0.934 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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