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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3763354
log Bayes Factor = 37.1041
Chromosome 6   position 32,786,917  (GRCh37) Explore rs3763354 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.992 0.008 0.000
G37 Other demyelinating diseases of central nervous system
0.990 0.010 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.985 0.015 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.891 0.109 0.000
E03 Other hypothyroidism
0.000 0.158 0.842
G36 Other acute disseminated demyelination
0.779 0.220 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.760 0.240 0.000
E03.8 Other specified hypothyroidism
0.000 0.260 0.740
G37.5 Concentric sclerosis [Balo]
0.710 0.290 0.000
G37.4 Subacute necrotising myelitis
0.710 0.290 0.000
G37.2 Central pontine myelinolysis
0.710 0.290 0.000
G37.1 Central demyelination of corpus callosum
0.710 0.290 0.000
G37.0 Diffuse sclerosis
0.710 0.290 0.000
G36.0 Neuromyelitis optica [Devic]
0.627 0.373 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.383 0.617
E03.5 Myxoedema coma
0.000 0.396 0.604
E03.4 Atrophy of thyroid (acquired)
0.000 0.396 0.604
E03.3 Postinfectious hypothyroidism
0.000 0.396 0.604
E03.1 Congenital hypothyroidism without goitre
0.000 0.396 0.604
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.396 0.604
E83.1 Disorders of iron metabolism
0.574 0.425 0.000
E00-E07 Disorders of thyroid gland
0.000 0.439 0.561
G36.9 Acute disseminated demyelination, unspecified
0.559 0.441 0.000
G36.8 Other specified acute disseminated demyelination
0.559 0.441 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.559 0.441 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.511 0.489
E06 Thyroiditis
0.000 0.536 0.464
E05.9 Thyrotoxicosis, unspecified
0.000 0.579 0.421
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.582 0.418
E06.3 Autoimmune thyroiditis
0.000 0.582 0.418
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.586 0.414
E20-E35 Disorders of other endocrine glands
0.000 0.587 0.413
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.597 0.403
E00 Congenital iodine-deficiency syndrome
0.000 0.597 0.403
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.598 0.402
E23 Hypofunction and other disorders of pituitary gland
0.000 0.603 0.397
E21.0 Primary hyperparathyroidism
0.000 0.623 0.377
E24 Cushing's syndrome
0.000 0.629 0.371
E78.0 Pure hypercholesterolaemia
0.000 0.633 0.367
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.637 0.363
E70-E90 Metabolic disorders
0.000 0.645 0.355
E05.5 Thyroid crisis or storm
0.000 0.649 0.351
E05.4 Thyrotoxicosis factitia
0.000 0.649 0.351
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.649 0.351
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.649 0.351
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.650 0.350
E23.6 Other disorders of pituitary gland
0.000 0.651 0.349
E23.7 Disorder of pituitary gland, unspecified
0.000 0.653 0.347
E06.9 Thyroiditis, unspecified
0.000 0.658 0.342
E05.8 Other thyrotoxicosis
0.000 0.660 0.340
E21.3 Hyperparathyroidism, unspecified
0.000 0.660 0.340
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.662 0.337
E78.5 Hyperlipidaemia, unspecified
0.000 0.667 0.333
E06.4 Drug-induced thyroiditis
0.000 0.667 0.333
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.667 0.333
E06.0 Acute thyroiditis
0.000 0.667 0.333
E23.2 Diabetes insipidus
0.000 0.669 0.331
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.674 0.325
E24.9 Cushing's syndrome, unspecified
0.000 0.675 0.325
E06.5 Other chronic thyroiditis
0.000 0.687 0.312
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.688 0.312
E28 Ovarian dysfunction
0.000 0.693 0.307
E24.2 Drug-induced Cushing's syndrome
0.000 0.696 0.304
E26 Hyperaldosteronism
0.000 0.697 0.303
E78.1 Pure hyperglyceridaemia
0.000 0.700 0.300
E25 Adrenogenital disorders
0.000 0.701 0.299
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.704 0.296
E32 Diseases of thymus
0.000 0.704 0.296
E31 Polyglandular dysfunction
0.000 0.704 0.296
E30 Disorders of puberty, not elsewhere classified
0.000 0.704 0.296
E29 Testicular dysfunction
0.000 0.704 0.296
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.706 0.294
E23.0 Hypopituitarism
0.000 0.710 0.290
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.711 0.289
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.711 0.289
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.711 0.289
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.711 0.289
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.711 0.289
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.711 0.289
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.711 0.289
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.711 0.289
E85 Amyloidosis
0.000 0.711 0.288
E21.4 Other specified disorders of parathyroid gland
0.000 0.712 0.288
E21.2 Other hyperparathyroidism
0.000 0.712 0.288
E78.6 Lipoprotein deficiency
0.000 0.713 0.287
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.715 0.285
E23.1 Drug-induced hypopituitarism
0.000 0.715 0.285
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.717 0.283
E16 Other disorders of pancreatic internal secretion
0.000 0.720 0.280
E06.1 Subacute thyroiditis
0.000 0.720 0.280
E24.8 Other Cushing's syndrome
0.000 0.733 0.266
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.733 0.266
E24.3 Ectopic ACTH syndrome
0.000 0.733 0.266
E24.1 Nelson's syndrome
0.000 0.733 0.266
E24.0 Pituitary-dependent Cushing's disease
0.000 0.733 0.266
E34 Other endocrine disorders
0.000 0.734 0.266
E07 Other disorders of thyroid
0.000 0.738 0.262
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.743 0.257
E28.2 Polycystic ovarian syndrome
0.000 0.743 0.257
E40-E46 Malnutrition
0.000 0.743 0.257
E88 Other metabolic disorders
0.000 0.745 0.255
E84 Cystic fibrosis
0.000 0.745 0.254
E77 Disorders of glycoprotein metabolism
0.000 0.745 0.254
E76 Disorders of glycosaminoglycan metabolism
0.000 0.745 0.254
E72 Other disorders of amino-acid metabolism
0.000 0.745 0.254
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.745 0.254
E70 Disorders of aromatic amino-acid metabolism
0.000 0.745 0.254
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.745 0.254
L57.0 Actinic keratosis
0.000 0.746 0.254
E78.8 Other disorders of lipoprotein metabolism
0.000 0.749 0.251
E20 Hypoparathyroidism
0.000 0.751 0.249
E79 Disorders of purine and pyrimidine metabolism
0.000 0.753 0.247
E74 Other disorders of carbohydrate metabolism
0.000 0.754 0.246
E04 Other non-toxic goitre
0.000 0.754 0.246
E85.9 Amyloidosis, unspecified
0.000 0.756 0.244
E15 Nondiabetic hypoglycaemic coma
0.000 0.758 0.242
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.759 0.241
E78.4 Other hyperlipidaemia
0.000 0.765 0.235
E80.4 Gilbert's syndrome
0.000 0.765 0.234
E16.1 Other hypoglycaemia
0.000 0.767 0.233
E26.0 Primary hyperaldosteronism
0.000 0.775 0.224
E78.3 Hyperchylomicronaemia
0.000 0.776 0.224
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.776 0.224
E28.9 Ovarian dysfunction, unspecified
0.000 0.780 0.220
E28.8 Other ovarian dysfunction
0.000 0.780 0.220
E28.1 Androgen excess
0.000 0.780 0.220
E28.0 Oestrogen excess
0.000 0.780 0.220
E26.9 Hyperaldosteronism, unspecified
0.000 0.782 0.217
E26.8 Other hyperaldosteronism
0.000 0.782 0.217
E26.1 Secondary hyperaldosteronism
0.000 0.782 0.217
E65-E68 Obesity and other hyperalimentation
0.000 0.783 0.217
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.783 0.216
E78.2 Mixed hyperlipidaemia
0.000 0.785 0.214
E25.9 Adrenogenital disorder, unspecified
0.000 0.786 0.214
E25.8 Other adrenogenital disorders
0.000 0.786 0.214
E30.9 Disorder of puberty, unspecified
0.000 0.787 0.212
E30.8 Other disorders of puberty
0.000 0.787 0.212
E30.1 Precocious puberty
0.000 0.787 0.212
E30.0 Delayed puberty
0.000 0.787 0.212
E31.9 Polyglandular dysfunction, unspecified
0.000 0.787 0.212
E31.8 Other polyglandular dysfunction
0.000 0.787 0.212
E31.1 Polyglandular hyperfunction
0.000 0.787 0.212
E31.0 Autoimmune polyglandular failure
0.000 0.787 0.212
E32.9 Disease of thymus, unspecified
0.000 0.787 0.212
E32.8 Other diseases of thymus
0.000 0.787 0.212
E32.1 Abscess of thymus
0.000 0.787 0.212
E32.0 Persistent hyperplasia of thymus
0.000 0.787 0.212
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.787 0.212
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.787 0.212
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.787 0.212
E29.9 Testicular dysfunction, unspecified
0.000 0.787 0.212
E29.8 Other testicular dysfunction
0.000 0.787 0.212
E29.0 Testicular hyperfunction
0.000 0.787 0.212
E29.1 Testicular hypofunction
0.000 0.787 0.212
E85.8 Other amyloidosis
0.000 0.793 0.207
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.793 0.207
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.793 0.207
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.793 0.207
E80.6 Other disorders of bilirubin metabolism
0.000 0.794 0.206
E85.4 Organ-limited amyloidosis
0.000 0.795 0.204
E85.3 Secondary systemic amyloidosis
0.000 0.796 0.204
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.797 0.203
E80.5 Crigler-Najjar syndrome
0.000 0.797 0.203
E80.3 Defects of catalase and peroxydase
0.000 0.797 0.203
E80.2 Other porphyria
0.000 0.797 0.203
E80.0 Hereditary erythropoietic porphyria
0.000 0.797 0.203
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.799 0.201
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.799 0.201
E16.4 Abnormal secretion of gastrin
0.000 0.799 0.201
E16.3 Increased secretion of glucagon
0.000 0.799 0.201
E73 Lactose intolerance
0.000 0.803 0.197
E80.1 Porphyria cutanea tarda
0.000 0.805 0.195
L72.1 Trichilemmal cyst
0.195 0.805 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.806 0.194
E34.8 Other specified endocrine disorders
0.000 0.806 0.194
E34.5 Androgen resistance syndrome
0.000 0.809 0.191
E34.4 Constitutional tall stature
0.000 0.809 0.191
E34.3 Short stature, not elsewhere classified
0.000 0.809 0.191
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.809 0.191
E34.1 Other hypersecretion of intestinal hormones
0.000 0.809 0.191
E10-E14 Diabetes mellitus
0.000 0.811 0.189
E07.1 Dyshormogenetic goitre
0.000 0.812 0.188
E07.0 Hypersecretion of calcitonin
0.000 0.812 0.188
E75.5 Other lipid storage disorders
0.000 0.813 0.187
E75.6 Lipid storage disorder, unspecified
0.000 0.816 0.184
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.816 0.184
E75.3 Sphingolipidosis, unspecified
0.000 0.816 0.184
E75.2 Other sphingolipidosis
0.000 0.816 0.184
E75.1 Other gangliosidosis
0.000 0.816 0.184
E75.0 GM2 gangliosidosis
0.000 0.816 0.184
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.816 0.184
E45 Retarded development following protein-energy malnutrition
0.000 0.816 0.184
E43 Unspecified severe protein-energy malnutrition
0.000 0.816 0.184
E42 Marasmic kwashiorkor
0.000 0.816 0.184
E41 Nutritional marasmus
0.000 0.816 0.184
E40 Kwashiorkor
0.000 0.816 0.184
E34.9 Endocrine disorder, unspecified
0.000 0.816 0.184
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.817 0.183
E88.9 Metabolic disorder, unspecified
0.000 0.817 0.183
E88.8 Other specified metabolic disorders
0.000 0.817 0.183
E88.3 Tumour lysis syndrome
0.000 0.817 0.183
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.817 0.183
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.817 0.183
E70.3 Albinism
0.000 0.817 0.183
E70.2 Disorders of tyrosine metabolism
0.000 0.817 0.183
E70.1 Other hyperphenylalaninaemias
0.000 0.817 0.183
E70.0 Classical phenylketonuria
0.000 0.817 0.183
E71.3 Disorders of fatty-acid metabolism
0.000 0.817 0.183
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.817 0.183
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.817 0.183
E71.0 Maple-syrup-urine disease
0.000 0.817 0.183
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.817 0.183
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.817 0.183
E72.5 Disorders of glycine metabolism
0.000 0.817 0.183
E72.4 Disorders of ornithine metabolism
0.000 0.817 0.183
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.817 0.183
E72.2 Disorders of urea cycle metabolism
0.000 0.817 0.183
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.817 0.183
E72.0 Disorders of amino-acid transport
0.000 0.817 0.183
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.817 0.183
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.817 0.183
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.817 0.183
E76.2 Other mucopolysaccharidoses
0.000 0.817 0.183
E76.1 Mucopolysaccharidosis, type II
0.000 0.817 0.183
E76.0 Mucopolysaccharidosis, type I
0.000 0.817 0.183
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.817 0.183
E77.8 Other disorders of glycoprotein metabolism
0.000 0.817 0.183
E77.1 Defects in glycoprotein degradation
0.000 0.817 0.183
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.817 0.183
E84.9 Cystic fibrosis, unspecified
0.000 0.817 0.183
E84.8 Cystic fibrosis with other manifestations
0.000 0.817 0.183
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.817 0.183
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.817 0.183
E04.9 Non-toxic goitre, unspecified
0.000 0.821 0.179
E20.8 Other hypoparathyroidism
0.000 0.821 0.178
E20.1 Pseudohypoparathyroidism
0.000 0.821 0.178
E20.0 Idiopathic hypoparathyroidism
0.000 0.821 0.178
E07.8 Other specified disorders of thyroid
0.000 0.821 0.178
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.822 0.177
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.822 0.177
E79.1 Lesch-Nyhan syndrome
0.000 0.822 0.177
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.823 0.177
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.823 0.177
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.823 0.177
E74.2 Disorders of galactose metabolism
0.000 0.823 0.177
E74.1 Disorders of fructose metabolism
0.000 0.823 0.177
E74.0 Glycogen storage disease
0.000 0.823 0.177
E04.8 Other specified non-toxic goitre
0.000 0.824 0.176
E28.3 Primary ovarian failure
0.000 0.824 0.175
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.826 0.174
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.830 0.170
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.830 0.170
E83 Disorders of mineral metabolism
0.036 0.830 0.134
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.831 0.169
E22 Hyperfunction of pituitary gland
0.000 0.833 0.167
E34.0 Carcinoid syndrome
0.000 0.834 0.166
E65 Localised adiposity
0.000 0.835 0.165
E67 Other hyperalimentation
0.000 0.844 0.155
E68 Sequelae of hyperalimentation
0.000 0.844 0.155
E13 Other specified diabetes mellitus
0.000 0.844 0.155
E04.0 Non-toxic diffuse goitre
0.000 0.846 0.154
E04.1 Non-toxic single thyroid nodule
0.000 0.849 0.151
E73.8 Other lactose intolerance
0.000 0.858 0.141
E73.1 Secondary lactase deficiency
0.000 0.858 0.141
E73.0 Congenital lactase deficiency
0.000 0.858 0.141
E46 Unspecified protein-energy malnutrition
0.000 0.859 0.141
E16.2 Hypoglycaemia, unspecified
0.000 0.860 0.140
K90 Intestinal malabsorption
0.000 0.862 0.137
E27 Other disorders of adrenal gland
0.000 0.864 0.136
E12 Malnutrition-related diabetes mellitus
0.000 0.864 0.135
E44.1 Mild protein-energy malnutrition
0.000 0.868 0.132
E44.0 Moderate protein-energy malnutrition
0.000 0.868 0.132
E13.9 Without complications
0.000 0.868 0.132
E20.9 Hypoparathyroidism, unspecified
0.000 0.869 0.131
E89.3 Postprocedural hypopituitarism
0.000 0.874 0.126
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.875 0.125
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.875 0.125
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.875 0.125
E89.5 Postprocedural testicular hypofunction
0.000 0.875 0.125
E89.2 Postprocedural hypoparathyroidism
0.000 0.876 0.124
E83.9 Disorder of mineral metabolism, unspecified
0.026 0.878 0.096
E83.8 Other disorders of mineral metabolism
0.026 0.878 0.096
E83.2 Disorders of zinc metabolism
0.026 0.878 0.096
E83.0 Disorders of copper metabolism
0.026 0.878 0.096
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.880 0.120
E22.8 Other hyperfunction of pituitary gland
0.000 0.880 0.120
E89.4 Postprocedural ovarian failure
0.000 0.882 0.117
E10 Insulin-dependent diabetes mellitus
0.000 0.887 0.113
E04.2 Non-toxic multinodular goitre
0.000 0.887 0.113
E67.8 Other specified hyperalimentation
0.000 0.888 0.112
E67.3 Hypervitaminosis D
0.000 0.888 0.112
E67.2 Megavitamin-B6 syndrome
0.000 0.888 0.112
E67.1 Hypercarotenaemia
0.000 0.888 0.112
E67.0 Hypervitaminosis A
0.000 0.888 0.112
E13.8 With unspecified complications
0.000 0.888 0.112
E13.7 With multiple complications
0.000 0.888 0.112
E13.6 With other specified complications
0.000 0.888 0.112
E13.5 With peripheral circulatory complications
0.000 0.888 0.112
E13.4 With neurological complications
0.000 0.888 0.112
E13.3 With ophthalmic complications
0.000 0.888 0.112
E13.2 With renal complications
0.000 0.888 0.112
E13.1 With ketoacidosis
0.000 0.888 0.112
E13.0 With coma
0.000 0.888 0.112
E89.1 Postprocedural hypoinsulinaemia
0.000 0.889 0.110
E83.3 Disorders of phosphorus metabolism
0.018 0.892 0.091
E83.4 Disorders of magnesium metabolism
0.009 0.892 0.099
E11 Non-insulin-dependent diabetes mellitus
0.000 0.892 0.108
L57 Skin changes due to chronic exposure to nonionising radiation
0.003 0.893 0.103
E22.1 Hyperprolactinaemia
0.000 0.894 0.106
E10.3 With ophthalmic complications
0.000 0.899 0.101
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.899 0.101
E50-E64 Other nutritional deficiencies
0.001 0.901 0.098
K90.3 Pancreatic steatorrhoea
0.000 0.901 0.099
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.901 0.099
K90.1 Tropical sprue
0.000 0.901 0.099
E27.5 Adrenomedullary hyperfunction
0.000 0.902 0.098
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.902 0.098
E27.0 Other adrenocortical overactivity
0.000 0.902 0.098
E12.9 Without complications
0.000 0.903 0.097
E12.8 With unspecified complications
0.000 0.903 0.097
E12.7 With multiple complications
0.000 0.903 0.097
E12.6 With other specified complications
0.000 0.903 0.097
E12.5 With peripheral circulatory complications
0.000 0.903 0.097
E12.4 With neurological complications
0.000 0.903 0.097
E12.3 With ophthalmic complications
0.000 0.903 0.097
E12.2 With renal complications
0.000 0.903 0.097
E12.1 With ketoacidosis
0.000 0.903 0.097
E12.0 With coma
0.000 0.903 0.097
L40.5 Arthropathic psoriasis
0.000 0.905 0.095
E11.9 Without complications
0.000 0.907 0.093
E27.9 Disorder of adrenal gland, unspecified
0.000 0.908 0.092
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.909 0.091
L40 Psoriasis
0.001 0.909 0.090
E27.8 Other specified disorders of adrenal gland
0.000 0.910 0.090
E10.0 With coma
0.000 0.910 0.090
K90.8 Other intestinal malabsorption
0.000 0.912 0.088
E11.6 With other specified complications
0.000 0.913 0.087
E10.5 With peripheral circulatory complications
0.000 0.913 0.087
L40.9 Psoriasis, unspecified
0.000 0.913 0.087
E89.0 Postprocedural hypothyroidism
0.000 0.914 0.086
E10.6 With other specified complications
0.000 0.914 0.086
E11.2 With renal complications
0.000 0.916 0.084
E73.9 Lactose intolerance, unspecified
0.001 0.916 0.083
E10.7 With multiple complications
0.000 0.919 0.081
E11.1 With ketoacidosis
0.000 0.919 0.081
E10.8 With unspecified complications
0.000 0.922 0.078
L40-L45 Papulosquamous disorders
0.003 0.922 0.075
E11.7 With multiple complications
0.000 0.923 0.077
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.002 0.923 0.075
L57.5 Actinic granuloma
0.002 0.923 0.074
L57.3 Poikiloderma of Civatte
0.002 0.923 0.074
L57.2 Cutis rhomboidalis nuchae
0.002 0.923 0.074
L57.1 Actinic reticuloid
0.002 0.923 0.074
E11.8 With unspecified complications
0.000 0.923 0.076
E27.1 Primary adrenocortical insufficiency
0.000 0.924 0.076
E10.2 With renal complications
0.000 0.928 0.072
L43 Lichen planus
0.001 0.928 0.071
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.929 0.071
E56 Other vitamin deficiencies
0.001 0.929 0.071
E51 Thiamine deficiency
0.001 0.929 0.071
E50 Vitamin A deficiency
0.001 0.929 0.071
E60 Dietary zinc deficiency
0.001 0.929 0.071
E59 Dietary selenium deficiency
0.001 0.929 0.071
E54 Ascorbic acid deficiency
0.001 0.929 0.071
E52 Niacin deficiency [pellagra]
0.001 0.929 0.071
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.007 0.929 0.064
E07.9 Disorder of thyroid, unspecified
0.000 0.929 0.071
E22.0 Acromegaly and pituitary gigantism
0.001 0.930 0.070
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.930 0.070
E10.4 With neurological complications
0.000 0.930 0.070
L40.1 Generalised pustular psoriasis
0.000 0.931 0.069
E58 Dietary calcium deficiency
0.001 0.931 0.069
E11.0 With coma
0.000 0.932 0.068
L43.9 Lichen planus, unspecified
0.000 0.932 0.068
E14 Unspecified diabetes mellitus
0.000 0.933 0.067
E11.5 With peripheral circulatory complications
0.000 0.933 0.067
L57.4 Cutis laxa senilis
0.003 0.933 0.064
E63 Other nutritional deficiencies
0.001 0.935 0.065
L40.4 Guttate psoriasis
0.001 0.935 0.065
L40.3 Pustulosis palmaris et plantaris
0.001 0.935 0.065
L40.2 Acrodermatitis continua
0.001 0.935 0.065
E11.3 With ophthalmic complications
0.000 0.939 0.061
E61 Deficiency of other nutrient elements
0.000 0.940 0.059
L40.0 Psoriasis vulgaris
0.000 0.940 0.059
E27.2 Addisonian crisis
0.001 0.943 0.056
L42 Pityriasis rosea
0.002 0.944 0.054
L44 Other papulosquamous disorders
0.003 0.944 0.054
L41 Parapsoriasis
0.003 0.944 0.054
L45 Papulosquamous disorders in diseases classified elsewhere
0.003 0.944 0.054
L56 Other acute skin changes due to ultraviolet radiation
0.004 0.944 0.052
L43.8 Other lichen planus
0.001 0.945 0.054
E10.1 With ketoacidosis
0.000 0.945 0.055
K90.9 Intestinal malabsorption, unspecified
0.000 0.947 0.052
E86 Volume depletion
0.000 0.948 0.052
L43.3 Subacute (active) lichen planus
0.001 0.948 0.051
L43.2 Lichenoid drug reaction
0.001 0.948 0.051
L43.1 Bullous lichen planus
0.001 0.948 0.051
L43.0 Hypertrophic lichen planus
0.001 0.948 0.051
E50.9 Vitamin A deficiency, unspecified
0.001 0.949 0.051
E50.8 Other manifestations of vitamin A deficiency
0.001 0.949 0.051
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.949 0.051
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.949 0.051
E50.5 Vitamin A deficiency with night blindness
0.001 0.949 0.051
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.949 0.051
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.949 0.051
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.949 0.051
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.949 0.051
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.949 0.051
E51.9 Thiamine deficiency, unspecified
0.001 0.949 0.051
E51.8 Other manifestations of thiamine deficiency
0.001 0.949 0.051
E51.2 Wernicke's encephalopathy
0.001 0.949 0.051
E51.1 Beriberi
0.001 0.949 0.051
E56.9 Vitamin deficiency, unspecified
0.001 0.949 0.051
E56.8 Deficiency of other vitamins
0.001 0.949 0.051
E56.1 Deficiency of vitamin K
0.001 0.949 0.051
E56.0 Deficiency of vitamin E
0.001 0.949 0.051
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.949 0.051
E64.8 Sequelae of other nutritional deficiencies
0.001 0.949 0.051
E64.3 Sequelae of rickets
0.001 0.949 0.051
E64.2 Sequelae of vitamin C deficiency
0.001 0.949 0.051
E64.1 Sequelae of vitamin A deficiency
0.001 0.949 0.051
E64.0 Sequelae of protein-energy malnutrition
0.001 0.949 0.051
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.005 0.949 0.046
L58 Radiodermatitis
0.005 0.949 0.046
L55 Sunburn
0.005 0.949 0.046
E14.1 With ketoacidosis
0.000 0.950 0.050
E14.4 With neurological complications
0.000 0.950 0.049
E83.5 Disorders of calcium metabolism
0.007 0.951 0.043
E14.7 With multiple complications
0.000 0.951 0.048
E14.0 With coma
0.000 0.951 0.048
E14.3 With ophthalmic complications
0.000 0.952 0.048
E14.5 With peripheral circulatory complications
0.000 0.952 0.048
L72 Follicular cysts of skin and subcutaneous tissue
0.047 0.953 0.001
E63.8 Other specified nutritional deficiencies
0.001 0.953 0.047
E63.1 Imbalance of constituents of food intake
0.001 0.953 0.047
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.953 0.047
E14.8 With unspecified complications
0.000 0.953 0.047
E14.2 Withrenal complications
0.000 0.954 0.046
L40.8 Other psoriasis
0.001 0.954 0.045
E55 Vitamin D deficiency
0.001 0.954 0.045
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.002 0.955 0.043
E66 Obesity
0.000 0.955 0.045
E14.6 With other specified complications
0.000 0.956 0.044
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.002 0.956 0.041
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.002 0.957 0.041
E61.9 Deficiency of nutrient element, unspecified
0.000 0.957 0.043
E61.8 Deficiency of other specified nutrient elements
0.000 0.957 0.043
E61.7 Deficiency of multiple nutrient elements
0.000 0.957 0.043
E61.6 Vanadium deficiency
0.000 0.957 0.043
E61.5 Molybdenum deficiency
0.000 0.957 0.043
E61.4 Chromium deficiency
0.000 0.957 0.043
E61.3 Manganese deficiency
0.000 0.957 0.043
E61.0 Copper deficiency
0.000 0.957 0.043
E63.9 Nutritional deficiency, unspecified
0.001 0.959 0.041
L41.9 Parapsoriasis, unspecified
0.002 0.959 0.039
L41.8 Other parapsoriasis
0.002 0.959 0.039
L41.5 Retiform parapsoriasis
0.002 0.959 0.039
L41.4 Large plaque parapsoriasis
0.002 0.959 0.039
L41.3 Small plaque parapsoriasis
0.002 0.959 0.039
L41.2 Lymphomatoid papulosis
0.002 0.959 0.039
L41.1 Pityriasis lichenoides chronica
0.002 0.959 0.039
L41.0 Pityriasis lichenoides et varioliformis acuta
0.002 0.959 0.039
L44.9 Papulosquamous disorder, unspecified
0.002 0.959 0.039
L44.8 Other specified papulosquamous disorders
0.002 0.959 0.039
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.002 0.959 0.039
L44.3 Lichen ruber moniliformis
0.002 0.959 0.039
L44.2 Lichen striatus
0.002 0.959 0.039
L44.1 Lichen nitidus
0.002 0.959 0.039
L44.0 Pityriasis rubra pilaris
0.002 0.959 0.039
L56.4 Polymorphous light eruption
0.003 0.959 0.038
L56.3 Solar urticaria
0.003 0.959 0.038
L56.2 Photocontact dermatitis [berloque dermatitis]
0.003 0.959 0.038
L56.1 Drug photoallergic response
0.003 0.959 0.038
L56.0 Drug phototoxic response
0.003 0.959 0.038
E61.2 Magnesium deficiency
0.001 0.960 0.039
Chapter XII Diseases of the skin and subcutaneous tissue
0.016 0.962 0.022
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.038 0.962 0.000
L55.9 Sunburn, unspecified
0.004 0.963 0.033
L55.8 Other sunburn
0.004 0.963 0.033
L55.2 Sunburn of third degree
0.004 0.963 0.033
L55.1 Sunburn of second degree
0.004 0.963 0.033
L55.0 Sunburn of first degree
0.004 0.963 0.033
L58.9 Radiodermatitis, unspecified
0.004 0.963 0.033
L58.1 Chronic radiodermatitis
0.004 0.963 0.033
L58.0 Acute radiodermatitis
0.004 0.963 0.033
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.004 0.963 0.033
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.004 0.963 0.033
L59.0 Erythema ab igne [dermatitis ab igne]
0.004 0.963 0.033
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.036 0.964 0.000
E61.1 Iron deficiency
0.000 0.964 0.036
E10.9 Without complications
0.000 0.964 0.036
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.965 0.034
L72.2 Steatocystoma multiplex
0.034 0.966 0.001
E53 Deficiency of other B group vitamins
0.001 0.966 0.033
E55.0 Rickets, active
0.001 0.967 0.032
E66.1 Drug-induced obesity
0.000 0.968 0.032
E66.0 Obesity due to excess calories
0.000 0.969 0.031

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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