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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs376877
log Bayes Factor = 56.0585
Chromosome 6   position 33,024,606  (GRCh37) Explore rs376877 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
E10.1 With ketoacidosis
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.986 0.014 0.000
E10.4 With neurological complications
0.966 0.034 0.000
E10.2 With renal complications
0.966 0.034 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.949 0.051 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.944 0.056 0.000
E05.9 Thyrotoxicosis, unspecified
0.940 0.060 0.000
E00-E07 Disorders of thyroid gland
0.938 0.062 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.933 0.067 0.000
E14 Unspecified diabetes mellitus
0.932 0.068 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.931 0.069 0.000
E16 Other disorders of pancreatic internal secretion
0.921 0.079 0.000
E16.2 Hypoglycaemia, unspecified
0.914 0.086 0.000
E10.5 With peripheral circulatory complications
0.901 0.099 0.000
K90 Intestinal malabsorption
0.898 0.102 0.000
E14.3 With ophthalmic complications
0.868 0.132 0.000
K90.9 Intestinal malabsorption, unspecified
0.822 0.178 0.000
E10.0 With coma
0.802 0.198 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.801 0.199 0.000
E14.8 With unspecified complications
0.796 0.204 0.000
E10.8 With unspecified complications
0.789 0.211 0.000
E14.4 With neurological complications
0.758 0.242 0.000
E13 Other specified diabetes mellitus
0.750 0.250 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.723 0.277 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E14.6 With other specified complications
0.713 0.286 0.000
E10.6 With other specified complications
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.707 0.293 0.000
K90.8 Other intestinal malabsorption
0.706 0.294 0.000
E20-E35 Disorders of other endocrine glands
0.697 0.303 0.000
E14.1 With ketoacidosis
0.694 0.306 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.687 0.313 0.000
E05.5 Thyroid crisis or storm
0.677 0.323 0.000
E05.4 Thyrotoxicosis factitia
0.677 0.323 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.677 0.323 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.677 0.323 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.673 0.327 0.000
E00 Congenital iodine-deficiency syndrome
0.673 0.327 0.000
E14.5 With peripheral circulatory complications
0.670 0.330 0.000
E15 Nondiabetic hypoglycaemic coma
0.669 0.331 0.000
E14.7 With multiple complications
0.668 0.332 0.000
E14.2 Withrenal complications
0.668 0.332 0.000
E14.0 With coma
0.668 0.332 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.660 0.340 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.660 0.340 0.000
E16.4 Abnormal secretion of gastrin
0.660 0.340 0.000
E16.3 Increased secretion of glucagon
0.660 0.340 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.659 0.341 0.000
K90.3 Pancreatic steatorrhoea
0.644 0.356 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.644 0.356 0.000
K90.1 Tropical sprue
0.644 0.356 0.000
E65-E68 Obesity and other hyperalimentation
0.643 0.357 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.641 0.359 0.000
E21.0 Primary hyperparathyroidism
0.631 0.369 0.000
E26 Hyperaldosteronism
0.603 0.397 0.000
E05.8 Other thyrotoxicosis
0.587 0.413 0.000
E13.9 Without complications
0.581 0.419 0.000
E40-E46 Malnutrition
0.571 0.429 0.000
E11 Non-insulin-dependent diabetes mellitus
0.542 0.458 0.000
E13.8 With unspecified complications
0.538 0.462 0.000
E13.7 With multiple complications
0.538 0.462 0.000
E13.6 With other specified complications
0.538 0.462 0.000
E13.5 With peripheral circulatory complications
0.538 0.462 0.000
E13.4 With neurological complications
0.538 0.462 0.000
E13.3 With ophthalmic complications
0.538 0.462 0.000
E13.2 With renal complications
0.538 0.462 0.000
E13.1 With ketoacidosis
0.538 0.462 0.000
E13.0 With coma
0.538 0.462 0.000
E20 Hypoparathyroidism
0.536 0.464 0.000
E26.0 Primary hyperaldosteronism
0.535 0.465 0.000
E03 Other hypothyroidism
0.535 0.465 0.000
E24 Cushing's syndrome
0.531 0.469 0.000
E22 Hyperfunction of pituitary gland
0.516 0.484 0.000
E21.2 Other hyperparathyroidism
0.515 0.485 0.000
E11.3 With ophthalmic complications
0.515 0.485 0.000
E07 Other disorders of thyroid
0.509 0.491 0.000
E12.9 Without complications
0.507 0.493 0.000
E12.8 With unspecified complications
0.507 0.493 0.000
E12.7 With multiple complications
0.507 0.493 0.000
E12.6 With other specified complications
0.507 0.493 0.000
E12.5 With peripheral circulatory complications
0.507 0.493 0.000
E12.4 With neurological complications
0.507 0.493 0.000
E12.3 With ophthalmic complications
0.507 0.493 0.000
E12.2 With renal complications
0.507 0.493 0.000
E12.1 With ketoacidosis
0.507 0.493 0.000
E12.0 With coma
0.507 0.493 0.000
E16.1 Other hypoglycaemia
0.501 0.499 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.500 0.500 0.000
E32 Diseases of thymus
0.500 0.500 0.000
E31 Polyglandular dysfunction
0.500 0.500 0.000
E30 Disorders of puberty, not elsewhere classified
0.500 0.500 0.000
E25 Adrenogenital disorders
0.500 0.500 0.000
E34 Other endocrine disorders
0.488 0.512 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.482 0.518 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.482 0.518 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.482 0.518 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.482 0.518 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.482 0.518 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.482 0.518 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.482 0.518 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.482 0.518 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.472 0.527 0.000
E21.4 Other specified disorders of parathyroid gland
0.472 0.527 0.000
E67 Other hyperalimentation
0.461 0.539 0.000
E68 Sequelae of hyperalimentation
0.461 0.539 0.000
E21.3 Hyperparathyroidism, unspecified
0.458 0.542 0.000
E66 Obesity
0.448 0.552 0.000
E11.1 With ketoacidosis
0.446 0.554 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.441 0.559 0.000
E65 Localised adiposity
0.438 0.562 0.000
E06 Thyroiditis
0.434 0.566 0.000
E26.9 Hyperaldosteronism, unspecified
0.432 0.568 0.000
E26.8 Other hyperaldosteronism
0.432 0.568 0.000
E26.1 Secondary hyperaldosteronism
0.432 0.568 0.000
E03.8 Other specified hypothyroidism
0.429 0.571 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.423 0.577 0.000
E20.9 Hypoparathyroidism, unspecified
0.421 0.579 0.000
E11.5 With peripheral circulatory complications
0.417 0.583 0.000
E24.2 Drug-induced Cushing's syndrome
0.413 0.587 0.000
E22.1 Hyperprolactinaemia
0.411 0.589 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.409 0.590 0.000
E45 Retarded development following protein-energy malnutrition
0.409 0.590 0.000
E43 Unspecified severe protein-energy malnutrition
0.409 0.590 0.000
E42 Marasmic kwashiorkor
0.409 0.590 0.000
E41 Nutritional marasmus
0.409 0.590 0.000
E40 Kwashiorkor
0.409 0.590 0.000
E50-E64 Other nutritional deficiencies
0.407 0.592 0.000
E11.7 With multiple complications
0.389 0.611 0.000
E20.8 Other hypoparathyroidism
0.384 0.615 0.000
E20.1 Pseudohypoparathyroidism
0.384 0.615 0.000
E20.0 Idiopathic hypoparathyroidism
0.384 0.615 0.000
E03.5 Myxoedema coma
0.384 0.616 0.000
E03.4 Atrophy of thyroid (acquired)
0.384 0.616 0.000
E03.3 Postinfectious hypothyroidism
0.384 0.616 0.000
E03.1 Congenital hypothyroidism without goitre
0.384 0.616 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.384 0.616 0.000
E66.8 Other obesity
0.383 0.617 0.000
E24.9 Cushing's syndrome, unspecified
0.382 0.617 0.000
E24.8 Other Cushing's syndrome
0.381 0.619 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.381 0.619 0.000
E24.3 Ectopic ACTH syndrome
0.381 0.619 0.000
E24.1 Nelson's syndrome
0.381 0.619 0.000
E11.8 With unspecified complications
0.379 0.621 0.000
E24.0 Pituitary-dependent Cushing's disease
0.379 0.621 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.370 0.630 0.000
E22.8 Other hyperfunction of pituitary gland
0.370 0.630 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.369 0.631 0.000
E34.9 Endocrine disorder, unspecified
0.368 0.632 0.000
E07.8 Other specified disorders of thyroid
0.367 0.633 0.000
E29 Testicular dysfunction
0.366 0.633 0.000
E07.1 Dyshormogenetic goitre
0.365 0.635 0.000
E07.0 Hypersecretion of calcitonin
0.365 0.635 0.000
E25.9 Adrenogenital disorder, unspecified
0.358 0.641 0.000
E25.8 Other adrenogenital disorders
0.358 0.641 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.358 0.641 0.000
E30.9 Disorder of puberty, unspecified
0.358 0.641 0.000
E30.8 Other disorders of puberty
0.358 0.641 0.000
E30.1 Precocious puberty
0.358 0.641 0.000
E30.0 Delayed puberty
0.358 0.641 0.000
E31.9 Polyglandular dysfunction, unspecified
0.358 0.641 0.000
E31.8 Other polyglandular dysfunction
0.358 0.641 0.000
E31.1 Polyglandular hyperfunction
0.358 0.641 0.000
E31.0 Autoimmune polyglandular failure
0.358 0.641 0.000
E32.9 Disease of thymus, unspecified
0.358 0.641 0.000
E32.8 Other diseases of thymus
0.358 0.641 0.000
E32.1 Abscess of thymus
0.358 0.641 0.000
E32.0 Persistent hyperplasia of thymus
0.358 0.641 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.358 0.641 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.358 0.641 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.358 0.641 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.357 0.643 0.000
E23 Hypofunction and other disorders of pituitary gland
0.352 0.648 0.000
E11.0 With coma
0.351 0.649 0.000
E11.2 With renal complications
0.351 0.649 0.000
E34.5 Androgen resistance syndrome
0.350 0.650 0.000
E34.4 Constitutional tall stature
0.350 0.650 0.000
E34.3 Short stature, not elsewhere classified
0.350 0.650 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.350 0.650 0.000
E34.1 Other hypersecretion of intestinal hormones
0.350 0.650 0.000
E34.0 Carcinoid syndrome
0.348 0.652 0.000
E67.8 Other specified hyperalimentation
0.330 0.669 0.000
E67.3 Hypervitaminosis D
0.330 0.669 0.000
E67.2 Megavitamin-B6 syndrome
0.330 0.669 0.000
E67.1 Hypercarotenaemia
0.330 0.669 0.000
E67.0 Hypervitaminosis A
0.330 0.669 0.000
E66.1 Drug-induced obesity
0.321 0.679 0.000
E34.8 Other specified endocrine disorders
0.319 0.680 0.000
E06.5 Other chronic thyroiditis
0.311 0.689 0.000
E06.4 Drug-induced thyroiditis
0.311 0.689 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.311 0.689 0.000
E06.1 Subacute thyroiditis
0.311 0.689 0.000
E06.0 Acute thyroiditis
0.311 0.689 0.000
E58 Dietary calcium deficiency
0.306 0.694 0.000
E28 Ovarian dysfunction
0.303 0.697 0.000
E46 Unspecified protein-energy malnutrition
0.300 0.700 0.000
E14.9 Without complications
0.294 0.706 0.000
E44.1 Mild protein-energy malnutrition
0.294 0.706 0.000
E44.0 Moderate protein-energy malnutrition
0.294 0.706 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.292 0.708 0.000
E63 Other nutritional deficiencies
0.292 0.708 0.000
E56 Other vitamin deficiencies
0.292 0.708 0.000
E51 Thiamine deficiency
0.292 0.708 0.000
E50 Vitamin A deficiency
0.292 0.708 0.000
E60 Dietary zinc deficiency
0.292 0.708 0.000
E59 Dietary selenium deficiency
0.292 0.708 0.000
E54 Ascorbic acid deficiency
0.292 0.708 0.000
E52 Niacin deficiency [pellagra]
0.292 0.708 0.000
E11.6 With other specified complications
0.288 0.712 0.000
E06.9 Thyroiditis, unspecified
0.269 0.730 0.000
E29.9 Testicular dysfunction, unspecified
0.263 0.737 0.000
E29.8 Other testicular dysfunction
0.263 0.737 0.000
E29.0 Testicular hyperfunction
0.263 0.737 0.000
E23.7 Disorder of pituitary gland, unspecified
0.262 0.737 0.000
E61 Deficiency of other nutrient elements
0.252 0.748 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.252 0.748 0.000
E23.1 Drug-induced hypopituitarism
0.252 0.748 0.000
E66.0 Obesity due to excess calories
0.245 0.754 0.000
E23.2 Diabetes insipidus
0.239 0.760 0.000
E23.6 Other disorders of pituitary gland
0.238 0.762 0.000
E22.0 Acromegaly and pituitary gigantism
0.230 0.769 0.000
E55 Vitamin D deficiency
0.219 0.781 0.000
E28.9 Ovarian dysfunction, unspecified
0.217 0.782 0.000
E28.8 Other ovarian dysfunction
0.217 0.782 0.000
E28.1 Androgen excess
0.217 0.782 0.000
E28.0 Oestrogen excess
0.217 0.782 0.000
E66.9 Obesity, unspecified
0.210 0.790 0.000
E50.9 Vitamin A deficiency, unspecified
0.210 0.790 0.000
E50.8 Other manifestations of vitamin A deficiency
0.210 0.790 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.210 0.790 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.210 0.790 0.000
E50.5 Vitamin A deficiency with night blindness
0.210 0.790 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.210 0.790 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.210 0.790 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.210 0.790 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.210 0.790 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.210 0.790 0.000
E51.9 Thiamine deficiency, unspecified
0.210 0.790 0.000
E51.8 Other manifestations of thiamine deficiency
0.210 0.790 0.000
E51.2 Wernicke's encephalopathy
0.210 0.790 0.000
E51.1 Beriberi
0.210 0.790 0.000
E56.9 Vitamin deficiency, unspecified
0.210 0.790 0.000
E56.8 Deficiency of other vitamins
0.210 0.790 0.000
E56.1 Deficiency of vitamin K
0.210 0.790 0.000
E56.0 Deficiency of vitamin E
0.210 0.790 0.000
E63.9 Nutritional deficiency, unspecified
0.210 0.790 0.000
E63.8 Other specified nutritional deficiencies
0.210 0.790 0.000
E63.1 Imbalance of constituents of food intake
0.210 0.790 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.210 0.790 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.210 0.790 0.000
E64.8 Sequelae of other nutritional deficiencies
0.210 0.790 0.000
E64.3 Sequelae of rickets
0.210 0.790 0.000
E64.2 Sequelae of vitamin C deficiency
0.210 0.790 0.000
E64.1 Sequelae of vitamin A deficiency
0.210 0.790 0.000
E64.0 Sequelae of protein-energy malnutrition
0.210 0.790 0.000
E53 Deficiency of other B group vitamins
0.207 0.793 0.000
E27 Other disorders of adrenal gland
0.207 0.793 0.000
E61.2 Magnesium deficiency
0.200 0.800 0.000
E07.9 Disorder of thyroid, unspecified
0.196 0.804 0.000
E11.4 With neurological complications
0.189 0.811 0.000
Z89.5 Acquired absence of leg at or below knee
0.188 0.812 0.000
Z89 Acquired absence of limb
0.185 0.815 0.000
E61.9 Deficiency of nutrient element, unspecified
0.181 0.819 0.000
E61.8 Deficiency of other specified nutrient elements
0.181 0.819 0.000
E61.7 Deficiency of multiple nutrient elements
0.181 0.819 0.000
E61.6 Vanadium deficiency
0.181 0.819 0.000
E61.5 Molybdenum deficiency
0.181 0.819 0.000
E61.4 Chromium deficiency
0.181 0.819 0.000
E61.3 Manganese deficiency
0.181 0.819 0.000
E61.0 Copper deficiency
0.181 0.819 0.000
Z89.6 Acquired absence of leg above knee
0.180 0.820 0.000
E28.3 Primary ovarian failure
0.178 0.821 0.001
E06.3 Autoimmune thyroiditis
0.164 0.836 0.001
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]
0.162 0.838 0.000
E03.9 Hypothyroidism, unspecified
0.159 0.841 0.000
E55.0 Rickets, active
0.157 0.843 0.000
E53.9 Vitamin B deficiency, unspecified
0.154 0.845 0.000
Z89.4 Acquired absence of foot and ankle
0.152 0.848 0.000
E53.1 Pyridoxine deficiency
0.149 0.851 0.000
E53.0 Riboflavin deficiency
0.149 0.851 0.000
E27.5 Adrenomedullary hyperfunction
0.149 0.851 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.149 0.851 0.000
E27.0 Other adrenocortical overactivity
0.149 0.851 0.000
Z89.8 Acquired absence of upper and lower limbs [any level]
0.145 0.855 0.000
E27.2 Addisonian crisis
0.145 0.855 0.000
Z89.9 Acquired absence of limb, unspecified
0.142 0.858 0.000
Z89.2 Acquired absence of upper limb above wrist
0.140 0.860 0.000
E23.0 Hypopituitarism
0.137 0.863 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.865 0.135
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.133 0.867 0.000
Z89.3 Acquired absence of both upper limbs [any level]
0.133 0.867 0.000
Z89.1 Acquired absence of hand and wrist
0.133 0.867 0.000
E29.1 Testicular hypofunction
0.129 0.870 0.001
E04 Other non-toxic goitre
0.126 0.874 0.000
E27.1 Primary adrenocortical insufficiency
0.125 0.875 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.124 0.876 0.000
E27.8 Other specified disorders of adrenal gland
0.110 0.889 0.000
E28.2 Polycystic ovarian syndrome
0.108 0.891 0.001
E27.9 Disorder of adrenal gland, unspecified
0.106 0.894 0.000
E61.1 Iron deficiency
0.100 0.899 0.000
E04.8 Other specified non-toxic goitre
0.090 0.909 0.000
Q50-Q56 Congenital malformations of genital organs
0.088 0.912 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.084 0.916 0.000
E55.9 Vitamin D deficiency, unspecified
0.083 0.916 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.083 0.917 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.081 0.919 0.000
Q51 Congenital malformations of uterus and cervix
0.079 0.921 0.000
Q80-Q89 Other congenital malformations
0.077 0.923 0.000
Q23 Congenital malformations of aortic and mitral valves
0.077 0.923 0.000
Q21 Congenital malformations of cardiac septa
0.077 0.923 0.000
Q55 Other congenital malformations of male genital organs
0.075 0.925 0.000
Q23.1 Congenital insufficiency of aortic valve
0.074 0.926 0.000
Q21.1 Atrial septal defect
0.074 0.926 0.000
Q54 Hypospadias
0.072 0.928 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.072 0.928 0.000
Q24 Other congenital malformations of heart
0.071 0.929 0.000
Q51.3 Bicornate uterus
0.071 0.929 0.000
Q85 Phakomatoses, not elsewhere classified
0.070 0.930 0.000
Q50.5 Embryonic cyst of broad ligament
0.070 0.930 0.000
E04.0 Non-toxic diffuse goitre
0.068 0.931 0.000
E04.2 Non-toxic multinodular goitre
0.068 0.932 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.068 0.932 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.067 0.933 0.000
Q53 Undescended testicle
0.067 0.933 0.000
Q55.6 Other congenital malformations of penis
0.066 0.934 0.000
Q52 Other congenital malformations of female genitalia
0.063 0.936 0.000
Q89 Other congenital malformations, not elsewhere classified
0.063 0.937 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.063 0.937 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.063 0.937 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.063 0.937 0.000
Q25 Congenital malformations of great arteries
0.063 0.937 0.000
Q54.0 Hypospadias, balanic
0.062 0.938 0.000
Q54.1 Hypospadias, penile
0.061 0.939 0.000
Q35-Q37 Cleft lip and cleft palate
0.060 0.939 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.060 0.939 0.000
Q26 Congenital malformations of great veins
0.060 0.940 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.060 0.940 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.060 0.940 0.000
Q39 Congenital malformations of oesophagus
0.059 0.940 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.059 0.941 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.059 0.941 0.000
Q00-Q07 Congenital malformations of the nervous system
0.059 0.941 0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament
0.058 0.941 0.000
Q50.3 Other congenital malformations of ovary
0.058 0.941 0.000
Q50.2 Congenital torsion of ovary
0.058 0.941 0.000
Q50.1 Developmental ovarian cyst
0.058 0.941 0.000
Q50.0 Congenital absence of ovary
0.058 0.941 0.000
K90-K93 Other diseases of the digestive system
0.057 0.943 0.000
Q24.8 Other specified congenital malformations of heart
0.057 0.943 0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified
0.057 0.943 0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts
0.057 0.943 0.000
Q51.6 Embryonic cyst of cervix
0.057 0.943 0.000
Q51.5 Agenesis and aplasia of cervix
0.057 0.943 0.000
Q51.4 Unicornate uterus
0.057 0.943 0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina
0.057 0.943 0.000
Q51.0 Agenesis and aplasia of uterus
0.057 0.943 0.000
Q83 Congenital malformations of breast
0.056 0.944 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.056 0.944 0.000
Q84 Other congenital malformations of integument
0.056 0.944 0.000
Q81 Epidermolysis bullosa
0.056 0.944 0.000
Q80 Congenital ichthyosis
0.056 0.944 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.055 0.944 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.055 0.944 0.000
Q23.4 Hypoplastic left heart syndrome
0.055 0.944 0.000
Q23.3 Congenital mitral insufficiency
0.055 0.944 0.000
Q23.2 Congenital mitral stenosis
0.055 0.944 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.055 0.944 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.055 0.945 0.000
Q21.8 Other congenital malformations of cardiac septa
0.055 0.945 0.000
Q21.4 Aortopulmonary septal defect
0.055 0.945 0.000
Q21.3 Tetralogy of Fallot
0.055 0.945 0.000
Q21.2 Atrioventricular septal defect
0.055 0.945 0.000
Q60-Q64 Congenital malformations of the urinary system
0.055 0.945 0.000
Q24.0 Dextrocardia
0.054 0.946 0.000
Q55.9 Congenital malformation of male genital organ, unspecified
0.054 0.946 0.000
Q55.8 Other specified congenital malformations of male genital organs
0.054 0.946 0.000
Q55.5 Congenital absence and aplasia of penis
0.054 0.946 0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate
0.054 0.946 0.000
Q55.3 Atresia of vas deferens
0.054 0.946 0.000
Q55.2 Other congenital malformations of testis and scrotum
0.054 0.946 0.000
Q55.1 Hypoplasia of testis and scrotum
0.054 0.946 0.000
Q55.0 Absence and aplasia of testis
0.054 0.946 0.000
Q24.5 Malformation of coronary vessels
0.053 0.947 0.000
Q89.2 Congenital malformations of other endocrine glands
0.053 0.947 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.053 0.947 0.000
Q39.4 Oesophageal web
0.052 0.948 0.000
Q28 Other congenital malformations of circulatory system
0.052 0.948 0.000
Q54.8 Other hypospadias
0.052 0.948 0.000
Q54.4 Congenital chordee
0.052 0.948 0.000
Q54.3 Hypospadias, perineal
0.052 0.948 0.000
Q54.2 Hypospadias, penoscrotal
0.052 0.948 0.000
Q23.0 Congenital stenosis of aortic valve
0.052 0.948 0.000
Q53.1 Undescended testicle, unilateral
0.052 0.948 0.000
Q82 Other congenital malformations of skin
0.051 0.949 0.000
Q27 Other congenital malformations of peripheral vascular system
0.051 0.949 0.000
Q24.6 Congenital heart block
0.051 0.949 0.000
Q24.4 Congenital subaortic stenosis
0.051 0.949 0.000
Q24.3 Pulmonary infundibular stenosis
0.051 0.949 0.000
Q24.2 Cor triatriatum
0.051 0.949 0.000
Q24.1 Levocardia
0.051 0.949 0.000
Q85.1 Tuberous sclerosis
0.050 0.949 0.000
Q85.9 Phakomatosis, unspecified
0.050 0.950 0.000
Q25.4 Other congenital malformations of aorta
0.049 0.951 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.049 0.951 0.000
Q45 Other congenital malformations of digestive system
0.049 0.951 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.049 0.951 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.049 0.951 0.000
Q40 Other congenital malformations of upper alimentary tract
0.049 0.951 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.049 0.951 0.000
Q51.2 Other doubling of uterus
0.048 0.952 0.000
E53.8 Deficiency of other specified B group vitamins
0.048 0.952 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.048 0.952 0.000
Q53.9 Undescended testicle, unspecified
0.048 0.952 0.000
Q53.2 Undescended testicle, bilateral
0.048 0.952 0.000
Q53.0 Ectopic testis
0.048 0.952 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.047 0.953 0.000
Q21.0 Ventricular septal defect
0.047 0.953 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.046 0.953 0.000
Q52.5 Fusion of labia
0.046 0.954 0.000
H36.0 Diabetic retinopathy
0.046 0.954 0.000
Q52.9 Congenital malformation of female genitalia, unspecified
0.046 0.954 0.000
Q52.8 Other specified congenital malformations of female genitalia
0.046 0.954 0.000
Q52.7 Other congenital malformations of vulva
0.046 0.954 0.000
Q52.6 Congenital malformation of clitoris
0.046 0.954 0.000
Q52.4 Other congenital malformations of vagina
0.046 0.954 0.000
Q52.3 Imperforate hymen
0.046 0.954 0.000
Q52.2 Congenital rectovaginal fistula
0.046 0.954 0.000
Q52.1 Doubling of vagina
0.046 0.954 0.000
Q52.0 Congenital absence of vagina
0.046 0.954 0.000
Q89.9 Congenital malformation, unspecified
0.046 0.954 0.000
Q89.8 Other specified congenital malformations
0.046 0.954 0.000
Q89.7 Multiple congenital malformations, not elsewhere classified
0.046 0.954 0.000
Q89.4 Conjoined twins
0.046 0.954 0.000
Q89.3 Situs inversus
0.046 0.954 0.000
Q89.1 Congenital malformations of adrenal gland
0.046 0.954 0.000
Q89.0 Congenital malformations of spleen
0.046 0.954 0.000
Q39.6 Diverticulum of oesophagus
0.045 0.954 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.045 0.954 0.000
Q96 Turner's syndrome
0.045 0.954 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.045 0.954 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.045 0.954 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.045 0.954 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.045 0.954 0.000
Q90 Down's syndrome
0.045 0.954 0.000
Q56.4 Indeterminate sex, unspecified
0.045 0.955 0.000
Q56.3 Pseudohermaphroditism, unspecified
0.045 0.955 0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified
0.045 0.955 0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified
0.045 0.955 0.000
Q56.0 Hermaphroditism, not elsewhere classified
0.045 0.955 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.045 0.955 0.000
Q25.8 Other congenital malformations of great arteries
0.045 0.955 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.045 0.955 0.000
Q25.6 Stenosis of pulmonary artery
0.045 0.955 0.000
Q25.5 Atresia of pulmonary artery
0.045 0.955 0.000
Q25.3 Stenosis of aorta
0.045 0.955 0.000
Q25.2 Atresia of aorta
0.045 0.955 0.000
Q25.0 Patent ductus arteriosus
0.045 0.955 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.045 0.955 0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance
0.045 0.955 0.000
Q87.4 Marfan's syndrome
0.044 0.955 0.000
Q61 Cystic kidney disease
0.044 0.956 0.000
Q12 Congenital lens malformations
0.044 0.956 0.000
Q25.1 Coarctation of aorta
0.044 0.956 0.000
Q34 Other congenital malformations of respiratory system
0.043 0.956 0.000
Q33 Congenital malformations of lung
0.043 0.956 0.000
Q32 Congenital malformations of trachea and bronchus
0.043 0.956 0.000
Q31 Congenital malformations of larynx
0.043 0.956 0.000
Q30 Congenital malformations of nose
0.043 0.956 0.000
Q37 Cleft palate with cleft lip
0.043 0.956 0.000
Q36 Cleft lip
0.043 0.956 0.000
Q35 Cleft palate
0.043 0.956 0.000
Q17 Other congenital malformations of ear
0.043 0.957 0.000
Q07 Other congenital malformations of nervous system
0.043 0.957 0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.043 0.957 0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.043 0.957 0.000
Q20.6 Isomerism of atrial appendages
0.043 0.957 0.000
Q20.5 Discordant atrioventricular connexion
0.043 0.957 0.000
Q20.4 Double inlet ventricle
0.043 0.957 0.000
Q20.3 Discordant ventriculoarterial connexion
0.043 0.957 0.000
Q20.2 Double outlet left ventricle
0.043 0.957 0.000
Q20.1 Double outlet right ventricle
0.043 0.957 0.000
Q20.0 Common arterial trunk
0.043 0.957 0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.043 0.957 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.043 0.957 0.000
Q22.6 Hypoplastic right heart syndrome
0.043 0.957 0.000
Q22.5 Ebstein's anomaly
0.043 0.957 0.000
Q22.4 Congenital tricuspid stenosis
0.043 0.957 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.043 0.957 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.043 0.957 0.000
Q22.1 Congenital pulmonary valve stenosis
0.043 0.957 0.000
Q22.0 Pulmonary valve atresia
0.043 0.957 0.000
Q26.9 Congenital malformation of great vein, unspecified
0.043 0.957 0.000
Q26.8 Other congenital malformations of great veins
0.043 0.957 0.000
Q26.6 Portal vein-hepatic artery fistula
0.043 0.957 0.000
Q26.5 Anomalous portal venous connexion
0.043 0.957 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.043 0.957 0.000
Q26.3 Partial anomalous pulmonary venous connexion
0.043 0.957 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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