TreeWAS – Variant ID: rs3778638

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03 Other hypothyroidism	0.597	0.402	0.001
L40.9 Psoriasis, unspecified	0.000	0.433	0.567
L40 Psoriasis	0.000	0.494	0.506
E03.8 Other specified hypothyroidism	0.476	0.523	0.001
L40.5 Arthropathic psoriasis	0.000	0.528	0.472
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.431	0.568	0.001
E03.5 Myxoedema coma	0.428	0.571	0.001
E03.4 Atrophy of thyroid (acquired)	0.428	0.571	0.001
E03.3 Postinfectious hypothyroidism	0.428	0.571	0.001
E03.1 Congenital hypothyroidism without goitre	0.428	0.571	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.428	0.571	0.001
L40.0 Psoriasis vulgaris	0.000	0.571	0.429
L40.4 Guttate psoriasis	0.000	0.637	0.363
L40.3 Pustulosis palmaris et plantaris	0.000	0.637	0.363
L40.2 Acrodermatitis continua	0.000	0.637	0.363
L40.1 Generalised pustular psoriasis	0.000	0.637	0.363
L40.8 Other psoriasis	0.000	0.639	0.361
K90 Intestinal malabsorption	0.000	0.675	0.325
K90.3 Pancreatic steatorrhoea	0.000	0.767	0.233
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.767	0.233
K90.1 Tropical sprue	0.000	0.767	0.233
K90.8 Other intestinal malabsorption	0.000	0.771	0.229
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.786	0.214
K90.9 Intestinal malabsorption, unspecified	0.000	0.794	0.206
E00-E07 Disorders of thyroid gland	0.186	0.808	0.006
E07 Other disorders of thyroid	0.184	0.814	0.003
E07.9 Disorder of thyroid, unspecified	0.185	0.815	0.000
S64.4 Injury of digital nerve of other finger	0.173	0.827	0.000
L40-L45 Papulosquamous disorders	0.000	0.830	0.170
E02 Subclinical iodine-deficiency hypothyroidism	0.136	0.860	0.004
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.134	0.862	0.004
E00 Congenital iodine-deficiency syndrome	0.134	0.862	0.004
E07.1 Dyshormogenetic goitre	0.132	0.866	0.002
E07.0 Hypersecretion of calcitonin	0.132	0.866	0.002
L44 Other papulosquamous disorders	0.000	0.878	0.122
L41 Parapsoriasis	0.000	0.878	0.122
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.878	0.122
L42 Pityriasis rosea	0.000	0.884	0.116
E07.8 Other specified disorders of thyroid	0.110	0.887	0.002
L43 Lichen planus	0.000	0.890	0.110
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.096	0.901	0.003
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.096	0.901	0.003
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.096	0.901	0.003
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.096	0.901	0.003
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.096	0.901	0.003
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.096	0.901	0.003
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.096	0.901	0.003
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.096	0.901	0.003
R05 Cough	0.000	0.908	0.092
L41.9 Parapsoriasis, unspecified	0.000	0.912	0.088
L41.8 Other parapsoriasis	0.000	0.912	0.088
L41.5 Retiform parapsoriasis	0.000	0.912	0.088
L41.4 Large plaque parapsoriasis	0.000	0.912	0.088
L41.3 Small plaque parapsoriasis	0.000	0.912	0.088
L41.2 Lymphomatoid papulosis	0.000	0.912	0.088
L41.1 Pityriasis lichenoides chronica	0.000	0.912	0.088
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.912	0.088
L44.9 Papulosquamous disorder, unspecified	0.000	0.912	0.088
L44.8 Other specified papulosquamous disorders	0.000	0.912	0.088
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.912	0.088
L44.3 Lichen ruber moniliformis	0.000	0.912	0.088
L44.2 Lichen striatus	0.000	0.912	0.088
L44.1 Lichen nitidus	0.000	0.912	0.088
L44.0 Pityriasis rubra pilaris	0.000	0.912	0.088
E06 Thyroiditis	0.076	0.919	0.005
L43.3 Subacute (active) lichen planus	0.000	0.921	0.079
L43.2 Lichenoid drug reaction	0.000	0.921	0.079
L43.1 Bullous lichen planus	0.000	0.921	0.079
L43.0 Hypertrophic lichen planus	0.000	0.921	0.079
L43.8 Other lichen planus	0.000	0.925	0.074
L43.9 Lichen planus, unspecified	0.000	0.928	0.072
S64 Injury of nerves at wrist and hand level	0.066	0.934	0.000
E06.5 Other chronic thyroiditis	0.058	0.938	0.003
E06.4 Drug-induced thyroiditis	0.054	0.942	0.004
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.054	0.942	0.004
E06.1 Subacute thyroiditis	0.054	0.942	0.004
E06.0 Acute thyroiditis	0.054	0.942	0.004
S64.2 Injury of radial nerve at wrist and hand level	0.057	0.943	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.053	0.947	0.000
N21.0 Calculus in bladder	0.053	0.947	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.048	0.952	0.000
S64.8 Injury of other nerves at wrist and hand level	0.048	0.952	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.046	0.954	0.000
S64.1 Injury of median nerve at wrist and hand level	0.041	0.959	0.000
E06.9 Thyroiditis, unspecified	0.031	0.964	0.005
E06.3 Autoimmune thyroiditis	0.030	0.966	0.004
E05 Thyrotoxicosis [hyperthyroidism]	0.024	0.968	0.008
K90-K93 Other diseases of the digestive system	0.000	0.970	0.030
S64.3 Injury of digital nerve of thumb	0.028	0.972	0.000
I27 Other pulmonary heart diseases	0.000	0.974	0.026
E04 Other non-toxic goitre	0.024	0.974	0.002
I27.2 Other secondary pulmonary hypertension	0.000	0.974	0.026
I27.9 Pulmonary heart disease, unspecified	0.000	0.975	0.025
I27.0 Primary pulmonary hypertension	0.000	0.976	0.024
E05.5 Thyroid crisis or storm	0.017	0.977	0.006
E05.4 Thyrotoxicosis factitia	0.017	0.977	0.006
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.017	0.977	0.006
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.017	0.977	0.006
N21 Calculus of lower urinary tract	0.022	0.978	0.000
E05.8 Other thyrotoxicosis	0.016	0.978	0.006
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.978	0.022
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.015	0.980	0.006
I27.8 Other specified pulmonary heart diseases	0.000	0.981	0.019
I27.1 Kyphoscoliotic heart disease	0.000	0.981	0.019
E04.8 Other specified non-toxic goitre	0.017	0.981	0.001
J47 Bronchiectasis	0.000	0.982	0.018
R47.0 Dysphasia and aphasia	0.000	0.982	0.018
N21.1 Calculus in urethra	0.018	0.982	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.983	0.017
I26 Pulmonary embolism	0.000	0.984	0.016
N21.9 Calculus of lower urinary tract, unspecified	0.016	0.984	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.984	0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.984	0.016
K93.1 Megacolon in Chagas' disease	0.000	0.984	0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.984	0.016
I47.1 Supraventricular tachycardia	0.016	0.984	0.000
E04.0 Non-toxic diffuse goitre	0.014	0.984	0.002
I47 Paroxysmal tachycardia	0.015	0.985	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.015	0.985	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.001	0.986	0.013
I47.2 Ventricular tachycardia	0.014	0.986	0.000
N21.8 Other lower urinary tract calculus	0.013	0.987	0.000
I47.0 Reentry ventricular arrhythmia	0.013	0.987	0.000
Y45.0 Opioids and related analgesics	0.000	0.987	0.013
I28 Other diseases of pulmonary vessels	0.000	0.988	0.012
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.988	0.012
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.989	0.011
J40 Bronchitis, not specified as acute or chronic	0.000	0.990	0.010
E04.2 Non-toxic multinodular goitre	0.009	0.990	0.001
E04.1 Non-toxic single thyroid nodule	0.009	0.990	0.001
E04.9 Non-toxic goitre, unspecified	0.008	0.991	0.001
E11 Non-insulin-dependent diabetes mellitus	0.000	0.991	0.009
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.991	0.009
I28.1 Aneurysm of pulmonary artery	0.000	0.991	0.009
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.991	0.009
E11.4 With neurological complications	0.000	0.991	0.009
E10.2 With renal complications	0.000	0.991	0.009
N75.0 Cyst of Bartholin's gland	0.000	0.991	0.009
E10.3 With ophthalmic complications	0.000	0.992	0.008
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.992	0.008
E11.8 With unspecified complications	0.000	0.992	0.008
K91.4 Colostomy and enterostomy malfunction	0.000	0.992	0.008
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.008	0.992	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.992	0.008
E10-E14 Diabetes mellitus	0.000	0.992	0.008
E11.5 With peripheral circulatory complications	0.000	0.992	0.008
I28.8 Other specified diseases of pulmonary vessels	0.000	0.992	0.008
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.992	0.008
K91.1 Postgastric surgery syndromes	0.000	0.992	0.008
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.992	0.008
D86.9 Sarcoidosis, unspecified	0.000	0.992	0.008
J40-J47 Chronic lower respiratory diseases	0.000	0.992	0.008
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.992	0.008
K91.5 Postcholecystectomy syndrome	0.000	0.992	0.008
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.992	0.008
D75 Other diseases of blood and blood-forming organs	0.000	0.992	0.008
E11.0 With coma	0.000	0.993	0.007
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.993	0.007
E16.2 Hypoglycaemia, unspecified	0.000	0.993	0.007
E10.8 With unspecified complications	0.000	0.993	0.007
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.993	0.007
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.993	0.007
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.993	0.006
E16 Other disorders of pancreatic internal secretion	0.000	0.993	0.007
D75.1 Secondary polycythaemia	0.000	0.993	0.007
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.993	0.006
E11.2 With renal complications	0.000	0.993	0.007
E11.7 With multiple complications	0.000	0.993	0.007
E10.1 With ketoacidosis	0.000	0.993	0.007
E83.1 Disorders of iron metabolism	0.000	0.993	0.007
D86 Sarcoidosis	0.000	0.993	0.007
E13 Other specified diabetes mellitus	0.000	0.993	0.006
E11.6 With other specified complications	0.000	0.994	0.006
D75.0 Familial erythrocytosis	0.000	0.994	0.006
Y45.2 Propionic acid derivatives	0.000	0.994	0.006
E11.1 With ketoacidosis	0.000	0.994	0.006
E11.3 With ophthalmic complications	0.000	0.994	0.006
E65-E68 Obesity and other hyperalimentation	0.000	0.994	0.006
E10.7 With multiple complications	0.000	0.994	0.006
E12 Malnutrition-related diabetes mellitus	0.000	0.994	0.006
E50-E64 Other nutritional deficiencies	0.000	0.994	0.006
E05.9 Thyrotoxicosis, unspecified	0.002	0.994	0.004
D75.2 Essential thrombocytosis	0.000	0.994	0.006
J41 Simple and mucopurulent chronic bronchitis	0.000	0.994	0.006
Y45.4 Antirheumatics	0.000	0.994	0.006
R63.0 Anorexia	0.000	0.994	0.006
E10.0 With coma	0.000	0.994	0.006
E10.6 With other specified complications	0.000	0.994	0.006
K91.3 Postoperative intestinal obstruction	0.000	0.994	0.006
J46 Status asthmaticus	0.000	0.994	0.006
D86.8 Sarcoidosis of other and combined sites	0.000	0.994	0.006
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.994	0.006
E55 Vitamin D deficiency	0.000	0.994	0.005
E66 Obesity	0.000	0.994	0.006
D86.1 Sarcoidosis of lymph nodes	0.000	0.994	0.006
D86.0 Sarcoidosis of lung	0.000	0.994	0.006
Y45.8 Other analgesics and antipyretics	0.000	0.994	0.005
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.994	0.006
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.995	0.005
E55.9 Vitamin D deficiency, unspecified	0.000	0.995	0.005
Y45.5 4-Aminophenol derivatives	0.000	0.995	0.005
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.995	0.005
Y45.1 Salicylates	0.000	0.995	0.005
E10.5 With peripheral circulatory complications	0.000	0.995	0.005
R03.1 Nonspecific low blood-pressure reading	0.000	0.995	0.005
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.995	0.005
E13.9 Without complications	0.000	0.995	0.005
E10.4 With neurological complications	0.000	0.995	0.005
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.995	0.005
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.995	0.005
E16.4 Abnormal secretion of gastrin	0.000	0.995	0.005
E16.3 Increased secretion of glucagon	0.000	0.995	0.005
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.995	0.005
E16.1 Other hypoglycaemia	0.000	0.995	0.005
E66.8 Other obesity	0.000	0.995	0.005
E66.0 Obesity due to excess calories	0.000	0.995	0.005
E15 Nondiabetic hypoglycaemic coma	0.000	0.995	0.005
E65 Localised adiposity	0.000	0.995	0.005
D70 Agranulocytosis	0.000	0.995	0.005
D72 Other disorders of white blood cells	0.000	0.995	0.005
D86.3 Sarcoidosis of skin	0.000	0.995	0.005
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.995	0.005
E13.8 With unspecified complications	0.000	0.995	0.005
E13.7 With multiple complications	0.000	0.995	0.005
E13.6 With other specified complications	0.000	0.995	0.005
E13.5 With peripheral circulatory complications	0.000	0.995	0.005
E13.4 With neurological complications	0.000	0.995	0.005
E13.3 With ophthalmic complications	0.000	0.995	0.005
E13.2 With renal complications	0.000	0.995	0.005
E13.1 With ketoacidosis	0.000	0.995	0.005
E13.0 With coma	0.000	0.995	0.005
Z51.4 Preparatory care for treatment, not elsewhere classified	0.000	0.995	0.005
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
J44 Other chronic obstructive pulmonary disease	0.000	0.995	0.005
E40-E46 Malnutrition	0.000	0.995	0.004
C71.9 Brain, unspecified	0.005	0.995	0.000
E67 Other hyperalimentation	0.000	0.995	0.004
E68 Sequelae of hyperalimentation	0.000	0.995	0.004
D72.8 Other specified disorders of white blood cells	0.000	0.995	0.005
E12.9 Without complications	0.000	0.995	0.004
E12.8 With unspecified complications	0.000	0.995	0.004
E12.7 With multiple complications	0.000	0.995	0.004
E12.6 With other specified complications	0.000	0.995	0.004
E12.5 With peripheral circulatory complications	0.000	0.995	0.004
E12.4 With neurological complications	0.000	0.995	0.004
E12.3 With ophthalmic complications	0.000	0.995	0.004
E12.2 With renal complications	0.000	0.995	0.004
E12.1 With ketoacidosis	0.000	0.995	0.004
E12.0 With coma	0.000	0.995	0.004
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.995	0.004
E63 Other nutritional deficiencies	0.000	0.995	0.004
E56 Other vitamin deficiencies	0.000	0.995	0.004
E51 Thiamine deficiency	0.000	0.995	0.004
E50 Vitamin A deficiency	0.000	0.995	0.004
E60 Dietary zinc deficiency	0.000	0.995	0.004
E59 Dietary selenium deficiency	0.000	0.995	0.004
E58 Dietary calcium deficiency	0.000	0.995	0.004
E54 Ascorbic acid deficiency	0.000	0.995	0.004
E52 Niacin deficiency [pellagra]	0.000	0.995	0.004
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.995	0.005
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.995	0.004
J41.1 Mucopurulent chronic bronchitis	0.000	0.995	0.004
J41.0 Simple chronic bronchitis	0.000	0.995	0.004
J42 Unspecified chronic bronchitis	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.004	0.996	0.000
E61 Deficiency of other nutrient elements	0.000	0.996	0.004
E55.0 Rickets, active	0.000	0.996	0.004
E66.1 Drug-induced obesity	0.000	0.996	0.004
I80 Phlebitis and thrombophlebitis	0.000	0.996	0.004
C71 Malignant neoplasm of brain	0.004	0.996	0.000
D74 Methaemoglobinaemia	0.000	0.996	0.004
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.996	0.004
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.996	0.004
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.996	0.004
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.996	0.004
I84.9 Unspecified haemorrhoids without complication	0.004	0.996	0.000
C71.2 Temporal lobe	0.004	0.996	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.996	0.004
D72.1 Eosinophilia	0.000	0.996	0.004
O47.0 False labour before 37 completed weeks of gestation	0.000	0.996	0.004
D72.9 Disorder of white blood cells, unspecified	0.000	0.996	0.004
D72.0 Genetic anomalies of leukocytes	0.000	0.996	0.004
R02 Gangrene, not elsewhere classified	0.000	0.996	0.004
E27.1 Primary adrenocortical insufficiency	0.000	0.996	0.004
E53.1 Pyridoxine deficiency	0.000	0.996	0.004
E53.0 Riboflavin deficiency	0.000	0.996	0.004
N84.1 Polyp of cervix uteri	0.004	0.996	0.000
R31 Unspecified haematuria	0.004	0.996	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.996	0.004
E53.8 Deficiency of other specified B group vitamins	0.000	0.996	0.004
E14 Unspecified diabetes mellitus	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.996	0.003
E45 Retarded development following protein-energy malnutrition	0.000	0.996	0.003
E43 Unspecified severe protein-energy malnutrition	0.000	0.996	0.003
E42 Marasmic kwashiorkor	0.000	0.996	0.003
E41 Nutritional marasmus	0.000	0.996	0.003
E40 Kwashiorkor	0.000	0.996	0.003
E67.8 Other specified hyperalimentation	0.000	0.996	0.003
E67.3 Hypervitaminosis D	0.000	0.996	0.003
E67.2 Megavitamin-B6 syndrome	0.000	0.996	0.003
E67.1 Hypercarotenaemia	0.000	0.996	0.003
E67.0 Hypervitaminosis A	0.000	0.996	0.003
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.996	0.004
E50.9 Vitamin A deficiency, unspecified	0.000	0.996	0.003
E50.8 Other manifestations of vitamin A deficiency	0.000	0.996	0.003
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.996	0.003
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.996	0.003
E50.5 Vitamin A deficiency with night blindness	0.000	0.996	0.003
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.996	0.003
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.996	0.003
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.996	0.003
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.996	0.003
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.996	0.003
E51.9 Thiamine deficiency, unspecified	0.000	0.996	0.003
E51.8 Other manifestations of thiamine deficiency	0.000	0.996	0.003
E51.2 Wernicke's encephalopathy	0.000	0.996	0.003
E51.1 Beriberi	0.000	0.996	0.003
E56.9 Vitamin deficiency, unspecified	0.000	0.996	0.003
E56.8 Deficiency of other vitamins	0.000	0.996	0.003
E56.1 Deficiency of vitamin K	0.000	0.996	0.003
E56.0 Deficiency of vitamin E	0.000	0.996	0.003
E63.9 Nutritional deficiency, unspecified	0.000	0.996	0.003
E63.8 Other specified nutritional deficiencies	0.000	0.996	0.003
E63.1 Imbalance of constituents of food intake	0.000	0.996	0.003
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.996	0.003
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.996	0.003
E64.8 Sequelae of other nutritional deficiencies	0.000	0.996	0.003
E64.3 Sequelae of rickets	0.000	0.996	0.003
E64.2 Sequelae of vitamin C deficiency	0.000	0.996	0.003
E64.1 Sequelae of vitamin A deficiency	0.000	0.996	0.003
E64.0 Sequelae of protein-energy malnutrition	0.000	0.996	0.003
C71.4 Occipital lobe	0.003	0.996	0.000
C71.3 Parietal lobe	0.003	0.996	0.000
N85.2 Hypertrophy of uterus	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.997	0.003
E61.8 Deficiency of other specified nutrient elements	0.000	0.997	0.003
E61.7 Deficiency of multiple nutrient elements	0.000	0.997	0.003
E61.6 Vanadium deficiency	0.000	0.997	0.003
E61.5 Molybdenum deficiency	0.000	0.997	0.003
E61.4 Chromium deficiency	0.000	0.997	0.003
E61.3 Manganese deficiency	0.000	0.997	0.003
E61.2 Magnesium deficiency	0.000	0.997	0.003
E61.0 Copper deficiency	0.000	0.997	0.003
J43 Emphysema	0.000	0.997	0.003
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.997	0.003
C71.7 Brain stem	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
D12.7 Rectosigmoid junction	0.003	0.997	0.000
D74.9 Methaemoglobinaemia, unspecified	0.000	0.997	0.003
D74.8 Other methaemoglobinaemias	0.000	0.997	0.003
D74.0 Congenital methaemoglobinaemia	0.000	0.997	0.003
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.997	0.003
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.000	0.997	0.003
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.997	0.003
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.997	0.003
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.997	0.003
D76.3 Other histiocytosis syndromes	0.000	0.997	0.003
O69.1 Labour and delivery complicated by cord around neck, with compression	0.003	0.997	0.000
S00.8 Superficial injury of other parts of head	0.003	0.997	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.997	0.003
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
M20.1 Hallux valgus (acquired)	0.003	0.997	0.000
E61.1 Iron deficiency	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.000	0.997	0.003
K92.8 Other specified diseases of digestive system	0.000	0.997	0.003
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.000	0.997	0.003
E14.6 With other specified complications	0.000	0.997	0.003
E14.5 With peripheral circulatory complications	0.000	0.997	0.003
E14.8 With unspecified complications	0.000	0.997	0.003
E14.7 With multiple complications	0.000	0.997	0.003
E14.2 Withrenal complications	0.000	0.997	0.003
E14.0 With coma	0.000	0.997	0.003
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.002
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.002
J43.2 Centrilobular emphysema	0.000	0.997	0.003
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
E14.4 With neurological complications	0.000	0.997	0.003
D73 Diseases of spleen	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.000	0.997	0.003
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.997	0.003
K92.9 Disease of digestive system, unspecified	0.002	0.997	0.000
R63 Symptoms and signs concerning food and fluid intake	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.002
Y57.8 Other drugs and medicaments	0.000	0.997	0.003
J43.1 Panlobular emphysema	0.000	0.997	0.003
J43.0 MacLeod's syndrome	0.000	0.997	0.003
D80-D89 Certain disorders involving the immune mechanism	0.000	0.997	0.003
K92 Other diseases of digestive system	0.000	0.997	0.002
E14.1 With ketoacidosis	0.000	0.997	0.002
Y57.5 X-ray contrast media	0.000	0.997	0.003
C61 Malignant neoplasm of prostate	0.000	0.997	0.003
E34 Other endocrine disorders	0.000	0.997	0.002
Y57.6 Other diagnostic agents	0.000	0.997	0.003
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.997	0.003
E14.3 With ophthalmic complications	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.002
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.997	0.003
R63.5 Abnormal weight gain	0.000	0.997	0.002
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.002
Y57.7 Vitamins, not elsewhere classified	0.000	0.998	0.002
Y57.4 Pharmaceutical excipients	0.000	0.998	0.002
Y57.3 Alcohol deterrents	0.000	0.998	0.002
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
Y57.1 Lipotropic drugs	0.000	0.998	0.002
Y57.0 Appetite depressants [anorectics]	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
R63.3 Feeding difficulties and mismanagement	0.000	0.998	0.002
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
J43.8 Other emphysema	0.000	0.998	0.002
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.998	0.002
K50.8 Other Crohn's disease	0.000	0.998	0.002
D73.8 Other diseases of spleen	0.000	0.998	0.002
D73.4 Cyst of spleen	0.000	0.998	0.002
D73.3 Abscess of spleen	0.000	0.998	0.002
D73.2 Chronic congestive splenomegaly	0.000	0.998	0.002
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.000	0.998	0.002
R63.6 Insufficient intake of food and water due to self neglect	0.000	0.998	0.002
R63.2 Polyphagia	0.000	0.998	0.002
D84 Other immunodeficiencies	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E32 Diseases of thymus	0.000	0.998	0.002
E31 Polyglandular dysfunction	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E25 Adrenogenital disorders	0.000	0.998	0.002
N75 Diseases of Bartholin's gland	0.000	0.998	0.002
D73.1 Hypersplenism	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.000	0.998	0.002
D73.5 Infarction of spleen	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.998	0.002
C71.1 Frontal lobe	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
R09.0 Asphyxia	0.000	0.998	0.002
K50 Crohn's disease [regional enteritis]	0.000	0.998	0.002
E20 Hypoparathyroidism	0.000	0.998	0.002
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
E83 Disorders of mineral metabolism	0.000	0.998	0.002
K50.0 Crohn's disease of small intestine	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
R09.3 Abnormal sputum	0.000	0.998	0.002
R09.1 Pleurisy	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.000	0.998	0.002
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.998	0.002
E26 Hyperaldosteronism	0.000	0.998	0.002
R01 Cardiac murmurs and other cardiac sounds	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.998	0.002
R01.0 Benign and innocent cardiac murmurs	0.000	0.998	0.002
E29 Testicular dysfunction	0.000	0.998	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.998	0.002
E85 Amyloidosis	0.000	0.998	0.002
E28 Ovarian dysfunction	0.001	0.998	0.001
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
C21.0 Anus, unspecified	0.002	0.998	0.000
R63.4 Abnormal weight loss	0.000	0.998	0.002
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.998	0.002
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.998	0.002
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.998	0.002
E27.2 Addisonian crisis	0.000	0.998	0.002
K82.9 Disease of gallbladder, unspecified	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.001
E25.8 Other adrenogenital disorders	0.000	0.998	0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.001
E30.8 Other disorders of puberty	0.000	0.998	0.001
E30.1 Precocious puberty	0.000	0.998	0.001
E30.0 Delayed puberty	0.000	0.998	0.001
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.001
E31.8 Other polyglandular dysfunction	0.000	0.998	0.001
E31.1 Polyglandular hyperfunction	0.000	0.998	0.001
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations