TreeWAS – Variant ID: rs3784589

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.998	0.002
Chapter II Neoplasms	0.998	0.002
N18 Chronic renal failure	0.998	0.002
Chapter IX Diseases of the circulatory system	0.996	0.004
N18.3 Chronic kidney disease, stage 3	0.996	0.004
N17-N19 Renal failure	0.991	0.009
C15-C26 Malignant neoplasms of digestive organs	0.988	0.012
I60-I69 Cerebrovascular diseases	0.987	0.013
Chapter XIV Diseases of the genitourinary system	0.985	0.015
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.984	0.016
Chapter VI Diseases of the nervous system	0.982	0.018
D37-D48 Neoplasms of uncertain or unknown behaviour	0.980	0.020
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.972	0.028
N18.9 Chronic renal failure, unspecified	0.971	0.029
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.969	0.031
C64-C68 Malignant neoplasms of urinary tract	0.968	0.032
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.966	0.034
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.965	0.035
I26 Pulmonary embolism	0.961	0.039
I69 Sequelae of cerebrovascular disease	0.961	0.039
N00-N08 Glomerular diseases	0.960	0.040
G80-G83 Cerebral palsy and other paralytic syndromes	0.956	0.044
C67 Malignant neoplasm of bladder	0.946	0.054
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.945	0.055
N18.5 Chronic kidney disease, stage 5	0.942	0.058
S00-S09 Injuries to the head	0.940	0.060
C20 Malignant neoplasm of rectum	0.939	0.061
I05-I09 Chronic rheumatic heart diseases	0.932	0.068
G81 Hemiplegia	0.928	0.072
D46 Myelodysplastic syndromes	0.927	0.073
I69.3 Sequelae of cerebral infarction	0.927	0.073
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.926	0.074
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.924	0.076
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.916	0.084
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.914	0.086
Y57 Other and unspecified drugs and medicaments	0.911	0.089
C21 Malignant neoplasm of anus and anal canal	0.908	0.092
G81.9 Hemiplegia, unspecified	0.908	0.092
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.908	0.092
C45 Mesothelioma	0.904	0.096
N03 Chronic nephritic syndrome	0.897	0.103
V10-V19 Pedal cyclist injured in transport accident	0.892	0.108
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.891	0.109
D46.9 Myelodysplastic syndrome, unspecified	0.889	0.111
S00 Superficial injury of head	0.884	0.116
G00-G09 Inflammatory diseases of the central nervous system	0.881	0.119
I08 Multiple valve diseases	0.879	0.121
S90-S99 Injuries to the ankle and foot	0.878	0.122
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.878	0.122
I27 Other pulmonary heart diseases	0.876	0.124
Y95 Nosocomial condition	0.874	0.126
N18.0 End-stage renal disease	0.873	0.127
D69 Purpura and other haemorrhagic conditions	0.871	0.129
I08.0 Disorders of both mitral and aortic valves	0.870	0.130
D66 Hereditary factor VIII deficiency	0.867	0.133
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.866	0.134
Y42.7 Androgens and anabolic congeners	0.866	0.134
N02 Recurrent and persistent haematuria	0.865	0.134
G83 Other paralytic syndromes	0.859	0.141
Q20-Q28 Congenital malformations of the circulatory system	0.858	0.142
I60 Subarachnoid haemorrhage	0.854	0.146
D41.4 Bladder	0.853	0.147
N03.9 Unspecified	0.853	0.147
M70-M79 Other soft tissue disorders	0.848	0.152
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.847	0.153
G90-G99 Other disorders of the nervous system	0.846	0.154
C67.5 Bladder neck	0.845	0.155
C79 Secondary malignant neoplasm of other sites	0.844	0.156
Y52 Agents primarily affecting the cardiovascular system	0.844	0.156
Y42.0 Glucocorticoids and synthetic analogs	0.841	0.159
M86-M90 Other osteopathies	0.840	0.160
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.838	0.162
Chapter I Certain infectious and parasitic diseases	0.836	0.164
T20-T25 Burns and corrosions of external body surface, specified by site	0.834	0.166
N18.2 Chronic kidney disease, stage 2	0.832	0.168
Y43 Primarily systemic agents	0.830	0.170
S50-S59 Injuries to the elbow and forearm	0.829	0.171
N19 Unspecified renal failure	0.826	0.174
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.826	0.174
S02 Fracture of skull and facial bones	0.823	0.177
C49 Malignant neoplasm of other connective and soft tissue	0.822	0.178
Q80-Q89 Other congenital malformations	0.820	0.180
S80-S89 Injuries to the knee and lower leg	0.819	0.181
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.817	0.183
C67.0 Trigone of bladder	0.814	0.186
S00.1 Contusion of eyelid and periocular area	0.808	0.192
D69.6 Thrombocytopenia, unspecified	0.807	0.193
W50-W64 Exposure to animate mechanical forces	0.806	0.194
N02.8 Other	0.806	0.194
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.804	0.196
I27.0 Primary pulmonary hypertension	0.804	0.196
W00-W19 Falls	0.803	0.197
N25-N29 Other disorders of kidney and ureter	0.802	0.198
I65.2 Occlusion and stenosis of carotid artery	0.799	0.201
C45.9 Mesothelioma, unspecified	0.799	0.201
Y57.9 Drug or medicament, unspecified	0.798	0.202
C21.0 Anus, unspecified	0.797	0.203
V18 Pedal cyclist injured in noncollision transport accident	0.796	0.204
S06 Intracranial injury	0.794	0.206
C67.9 Bladder, unspecified	0.794	0.206
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.793	0.207
C26 Malignant neoplasm of other and ill-defined digestive organs	0.790	0.210
G30-G32 Other degenerative diseases of the nervous system	0.790	0.210
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.788	0.212
I10-I15 Hypertensive diseases	0.787	0.213
Y47 Sedatives, hypnotics and antianxiety drugs	0.787	0.213
G62 Other polyneuropathies	0.785	0.215
S82 Fracture of lower leg, including ankle	0.784	0.216
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.784	0.216
S02.2 Fracture of nasal bones	0.783	0.217
C66 Malignant neoplasm of ureter	0.783	0.217
V40-V49 Car occupant injured in transport accident	0.782	0.218
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.782	0.218
D80-D89 Certain disorders involving the immune mechanism	0.779	0.221
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.777	0.223
C21.1 Anal canal	0.776	0.224
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.776	0.224
S00.0 Superficial injury of scalp	0.776	0.224
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.773	0.227
Y60-Y69 Misadventures to patients during surgical and medical care	0.773	0.227
C45.0 Mesothelioma of pleura	0.772	0.228
M80-M85 Disorders of bone density and structure	0.770	0.230
C67.8 Overlapping lesion of bladder	0.769	0.231
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.768	0.232
Y51 Drugs primarily affecting the autonomic nervous system	0.767	0.233
X58-X59 Accidental exposure to other and unspecified factors	0.765	0.235
X50-X57 Overexertion, travel and privation	0.764	0.236
M87 Osteonecrosis	0.763	0.237
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.763	0.237
Y46 Antiepileptics and anti-Parkinsonism drugs	0.762	0.238
I61 Intracerebral haemorrhage	0.762	0.238
C18 Malignant neoplasm of colon	0.761	0.239
C16 Malignant neoplasm of stomach	0.760	0.240
X10-X19 Contact with heat and hot substances	0.759	0.241
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.757	0.243
G83.2 Monoplegia of upper limb	0.756	0.244
Y49 Psychotropic drugs, not elsewhere classified	0.754	0.246
S02.20 Fracture of nasal bones (closed)	0.754	0.246
I69.1 Sequelae of intracerebral haemorrhage	0.754	0.246
T79-T79 Certain early complications of trauma	0.753	0.247
I67 Other cerebrovascular diseases	0.753	0.247
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.750	0.250
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.749	0.251
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.748	0.252
Q00-Q07 Congenital malformations of the nervous system	0.748	0.252
M77 Other enthesopathies	0.747	0.253
I69.0 Sequelae of subarachnoid haemorrhage	0.743	0.257
Y52.4 Angiotensin-converting-enzyme inhibitors	0.742	0.258
V18.0 Driver injured in nontraffic accident	0.741	0.259
Q50-Q56 Congenital malformations of genital organs	0.739	0.260
W20-W49 Exposure to inanimate mechanical forces	0.739	0.261
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.739	0.261
M71 Other bursopathies	0.738	0.262
D41.2 Ureter	0.738	0.262
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.737	0.263
Q38-Q45 Other congenital malformations of the digestive system	0.737	0.263
C23 Malignant neoplasm of gallbladder	0.736	0.264
S00.7 Multiple superficial injuries of head	0.736	0.264
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.733	0.267
Q66 Congenital deformities of feet	0.731	0.269
M91-M94 Chondropathies	0.730	0.270
M05-M14 Inflammatory polyarthropathies	0.730	0.270
Y42.5 Other oestrogens and progestogens	0.728	0.272
C17 Malignant neoplasm of small intestine	0.728	0.272
S82.6 Fracture of lateral malleolus	0.728	0.272
N04 Nephrotic syndrome	0.724	0.275
C67.2 Lateral wall of bladder	0.722	0.278
Y57.8 Other drugs and medicaments	0.722	0.278
D69.4 Other primary thrombocytopenia	0.721	0.279
X40-X49 Accidental poisoning by and exposure to noxious substances	0.720	0.280
B07 Viral warts	0.720	0.280
S92 Fracture of foot, except ankle	0.719	0.281
Y45.1 Salicylates	0.718	0.282
G62.9 Polyneuropathy, unspecified	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
Y00-Y09 Assault	0.717	0.283
X85-X99 Assault	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W75-W84 Other accidental threats to breathing	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V98-V99 Other and unspecified transport accidents	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
V01-V09 Pedestrian injured in transport accident	0.717	0.283
Y57.5 X-ray contrast media	0.716	0.284
Q76 Congenital malformations of spine and bony thorax	0.716	0.284
Y59 Other and unspecified vaccines and biological substances	0.716	0.284
Y58 Bacterial vaccines	0.716	0.284
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284
Y53 Agents primarily affecting the gastro-intestinal system	0.716	0.284
Y50 Central nervous system stimulants, not elsewhere classified	0.716	0.284
Y48 Anaesthetics and therapeutic gases	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.715	0.285
C40-C41 Malignant neoplasms of bone and articular cartilage	0.715	0.285
N18.8 Other chronic renal failure	0.715	0.285
N18.1 Chronic kidney disease, stage 1	0.715	0.285
S05 Injury of eye and orbit	0.714	0.286
T66-T78 Other and unspecified effects of external causes	0.714	0.286
I00-I02 Acute rheumatic fever	0.714	0.286
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.714	0.286
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.713	0.287
S10-S19 Injuries to the neck	0.713	0.287
I70-I79 Diseases of arteries, arterioles and capillaries	0.711	0.289
G09 Sequelae of inflammatory diseases of central nervous system	0.711	0.289
V20-V29 Motorcycle rider injured in transport accident	0.710	0.290
M70 Soft tissue disorders related to use, overuse and pressure	0.710	0.290
Y40 Systemic antibiotics	0.710	0.290
S82.3 Fracture of lower end of tibia	0.709	0.291
N05 Unspecified nephritic syndrome	0.709	0.291
M40-M43 Deforming dorsopathies	0.709	0.291
M87.9 Osteonecrosis, unspecified	0.708	0.291
I68 Cerebrovascular disorders in diseases classified elsewhere	0.708	0.292
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.708	0.292
Y43.1 Antineoplastic antimetabolites	0.706	0.294
I28 Other diseases of pulmonary vessels	0.705	0.295
G93 Other disorders of brain	0.704	0.296
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.702	0.297
S00.3 Superficial injury of nose	0.702	0.298
C49.2 Connective and soft tissue of lower limb, including hip	0.702	0.298
I05 Rheumatic mitral valve diseases	0.701	0.299
I64 Stroke, not specified as haemorrhage or infarction	0.701	0.299
G01 Meningitis in bacterial diseases classified elsewhere	0.700	0.300
X20-X29 Contact with venomous animals and plants	0.700	0.300
W18 Other fall on same level	0.699	0.301
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.699	0.301
Y44 Agents primarily affecting blood constituents	0.699	0.301
T00-T07 Injuries involving multiple body regions	0.698	0.301
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.697	0.303
Q35-Q37 Cleft lip and cleft palate	0.697	0.303
Q30-Q34 Congenital malformations of the respiratory system	0.697	0.303
V80-V89 Other land transport accidents	0.697	0.303
G35-G37 Demyelinating diseases of the central nervous system	0.697	0.303
Q23 Congenital malformations of aortic and mitral valves	0.696	0.304
T33-T35 Frostbite	0.695	0.305
T26-T28 Burns and corrosions confined to eye and internal organs	0.695	0.305
C45.7 Mesothelioma of other sites	0.694	0.305
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.694	0.306
C68 Malignant neoplasm of other and unspecified urinary organs	0.694	0.306
C65 Malignant neoplasm of renal pelvis	0.694	0.306
G04 Encephalitis, myelitis and encephalomyelitis	0.693	0.307
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.693	0.307
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.693	0.307
C46 Kaposi's sarcoma	0.693	0.307
Y42.9 Other and unspecified hormone antagonists	0.692	0.308
Y42.4 Oral contraceptives	0.692	0.308
Y42.2 Antithyroid drugs	0.692	0.308
Y42.1 Thyroid hormones and substitutes	0.692	0.308
D55-D59 Haemolytic anaemias	0.692	0.308
M72 Fibroblastic disorders	0.692	0.308
S06.0 Concussion	0.691	0.309
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.691	0.309
V11 Pedal cyclist injured in collision with other pedal cycle	0.690	0.310
I67.9 Cerebrovascular disease, unspecified	0.690	0.310
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.689	0.310
G95 Other diseases of spinal cord	0.689	0.311
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.689	0.311
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.689	0.311
B15-B19 Viral hepatitis	0.689	0.311
N07 Hereditary nephropathy, not elsewhere classified	0.688	0.311
N06 Isolated proteinuria with specified morphological lesion	0.688	0.311
N01 Rapidly progressive nephritic syndrome	0.688	0.311
N00 Acute nephritic syndrome	0.688	0.311
I60.8 Other subarachnoid haemorrhage	0.688	0.312
S82.60 Fracture of lateral malleolus (closed)	0.688	0.312
G70-G73 Diseases of myoneural junction and muscle	0.687	0.313
N08 Glomerular disorders in diseases classified elsewhere	0.687	0.313
C18.2 Ascending colon	0.686	0.314
S56 Injury of muscle and tendon at forearm level	0.685	0.314
C67.6 Ureteric orifice	0.685	0.315
S91 Open wound of ankle and foot	0.683	0.317
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.682	0.318
C79.9 Secondary malignant neoplasm, unspecified site	0.682	0.318
D40.0 Prostate	0.681	0.319
I63 Cerebral infarction	0.681	0.319
Q27 Other congenital malformations of peripheral vascular system	0.680	0.320
C67.7 Urachus	0.678	0.322
C67.4 Posterior wall of bladder	0.678	0.322
C67.1 Dome of bladder	0.678	0.322
C67.3 Anterior wall of bladder	0.676	0.324
Y41 Other systemic anti-infectives and antiparasitics	0.676	0.324
G83.4 Cauda equina syndrome	0.675	0.325
Q83 Congenital malformations of breast	0.674	0.326
D69.9 Haemorrhagic condition, unspecified	0.674	0.326
S08 Traumatic amputation of part of head	0.674	0.326
S07 Crushing injury of head	0.674	0.326
S04 Injury of cranial nerves	0.674	0.326
S03 Dislocation, sprain and strain of joints and ligaments of head	0.674	0.326
G96 Other disorders of central nervous system	0.673	0.327
D86 Sarcoidosis	0.673	0.327
X60-X84 Intentional self-harm	0.672	0.328
I12 Hypertensive renal disease	0.670	0.330
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.670	0.330
M89 Other disorders of bone	0.670	0.330
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.670	0.330
I95-I99 Other and unspecified disorders of the circulatory system	0.670	0.330
M77.4 Metatarsalgia	0.669	0.331
C16.0 Cardia	0.669	0.331
M13 Other arthritis	0.668	0.332
I09 Other rheumatic heart diseases	0.668	0.332
I06 Rheumatic aortic valve diseases	0.668	0.332
W55 Bitten or struck by other mammals	0.668	0.332
I07 Rheumatic tricuspid valve diseases	0.668	0.332
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.333
C25 Malignant neoplasm of pancreas	0.667	0.333
G98 Other disorders of nervous system, not elsewhere classified	0.667	0.333
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.666	0.333
S06.9 Intracranial injury, unspecified	0.666	0.334
N17 Acute renal failure	0.666	0.334
G81.1 Spastic hemiplegia	0.665	0.334
G81.0 Flaccid hemiplegia	0.665	0.334
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.665	0.335
D46.7 Other myelodysplastic syndromes	0.664	0.335
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.664	0.335
D46.5 Refractory anaemia with multi-lineage dysplasia	0.664	0.335
D46.4 Refractory anaemia, unspecified	0.664	0.335
D46.3 Refractory anaemia with excess of blasts with transformation	0.664	0.335
D46.2 Refractory anaemia with excess of blasts	0.664	0.335
D46.1 Refractory anaemia with sideroblasts	0.664	0.335
D46.0 Refractory anaemia without sideroblasts, so stated	0.664	0.335
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.664	0.336
Y98 Lifestyle-related condition	0.664	0.336
Y97 Environmental-pollution-related condition	0.664	0.336
Y96 Work-related condition	0.664	0.336
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.663	0.337
S82.8 Fractures of other parts of lower leg	0.663	0.337
Y45.0 Opioids and related analgesics	0.663	0.337
M84 Disorders of continuity of bone	0.662	0.338
N25 Disorders resulting from impaired renal tubular function	0.662	0.338
Y91 Evidence of alcohol involvement determined by level of intoxication	0.661	0.339
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.661	0.339
D68 Other coagulation defects	0.660	0.340
N26 Unspecified contracted kidney	0.660	0.340
M76 Enthesopathies of lower limb, excluding foot	0.660	0.340
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.660	0.340
W19 Unspecified fall	0.659	0.341
T31 Burns classified according to extent of body surface involved	0.658	0.342
D48.5 Skin	0.658	0.342
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.658	0.342
M86 Osteomyelitis	0.657	0.342
M60-M63 Disorders of muscles	0.657	0.343
I27.2 Other secondary pulmonary hypertension	0.656	0.344
S82.30 Fracture of lower end of tibia (closed)	0.656	0.344
D67 Hereditary factor IX deficiency	0.655	0.345
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.655	0.345
G06 Intracranial and intraspinal abscess and granuloma	0.655	0.345
M71.2 Synovial cyst of popliteal space [Baker]	0.654	0.346
D47.3 Essential (haemorrhagic) thrombocythaemia	0.654	0.346
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.654	0.346
Y57.7 Vitamins, not elsewhere classified	0.653	0.347
Y57.6 Other diagnostic agents	0.653	0.347
Y57.4 Pharmaceutical excipients	0.653	0.347
Y57.3 Alcohol deterrents	0.653	0.347
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.653	0.347
Y57.1 Lipotropic drugs	0.653	0.347
Y57.0 Appetite depressants [anorectics]	0.653	0.347
A50-A64 Infections with a predominantly sexual mode of transmission	0.652	0.348
C21.8 Overlapping lesion of rectum, anus and anal canal	0.651	0.349
C21.2 Cloacogenic zone	0.651	0.349
N27 Small kidney of unknown cause	0.651	0.349
D41.9 Urinary organ, unspecified	0.651	0.349
D41.7 Other urinary organs	0.651	0.349
D41.3 Urethra	0.651	0.349
D41.1 Renal pelvis	0.651	0.349
B25-B34 Other viral diseases	0.651	0.349
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.651	0.349
Q82 Other congenital malformations of skin	0.650	0.350
Q21 Congenital malformations of cardiac septa	0.649	0.351
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.649	0.351
M45-M49 Spondylopathies	0.648	0.352
S70-S79 Injuries to the hip and thigh	0.648	0.352
C45.2 Mesothelioma of pericardium	0.648	0.352
C45.1 Mesothelioma of peritoneum	0.648	0.352
C26.0 Intestinal tract, part unspecified	0.648	0.352
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.647	0.353
G62.0 Drug-induced polyneuropathy	0.647	0.353
S60-S69 Injuries to the wrist and hand	0.646	0.354
Q24 Other congenital malformations of heart	0.644	0.356
G83.1 Monoplegia of lower limb	0.644	0.356
N03.8 Other	0.643	0.356
N03.7 Diffuse crescentic glomerulonephritis	0.643	0.356
N03.6 Dense deposit disease	0.643	0.356
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.643	0.356
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.643	0.356
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.643	0.356
N03.2 Diffuse membranous glomerulonephritis	0.643	0.356
N03.1 Focal and segmental glomerular lesions	0.643	0.356
N03.0 Minor glomerular abnormality	0.643	0.356
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.643	0.357
T20 Burn and corrosion of head and neck	0.643	0.357
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.643	0.357
R00 Abnormalities of heart beat	0.642	0.358
R00.2 Palpitations	0.641	0.359
B02 Zoster [herpes zoster]	0.641	0.359
Y43.4 Immunosuppressive agents	0.641	0.359
V19 Pedal cyclist injured in other and unspecified transport accidents	0.640	0.360
V17 Pedal cyclist injured in collision with fixed or stationary object	0.640	0.360
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.640	0.360
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.640	0.360
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.640	0.360
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.640	0.360
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.640	0.360
V10 Pedal cyclist injured in collision with pedestrian or animal	0.640	0.360
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.639	0.360
A80-A89 Viral infections of the central nervous system	0.639	0.361
Q28 Other congenital malformations of circulatory system	0.639	0.361
C76 Malignant neoplasm of other and ill-defined sites	0.639	0.361
M00-M03 Infectious arthropathies	0.639	0.361
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.639	0.361
S50 Superficial injury of forearm	0.638	0.361
D69.3 Idiopathic thrombocytopenic purpura	0.638	0.362
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.638	0.362
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.638	0.362
Chapter XXII Codes for special purposes	0.637	0.362
R47-R49 Symptoms and signs involving speech and voice	0.635	0.365
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.635	0.365
Y47.1 Benzodiazepines	0.635	0.365
S00.5 Superficial injury of lip and oral cavity	0.634	0.366
S00.4 Superficial injury of ear	0.634	0.366
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.633	0.367
I60.9 Subarachnoid haemorrhage, unspecified	0.633	0.367
S90 Superficial injury of ankle and foot	0.632	0.368
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.632	0.368
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.632	0.368
G00 Bacterial meningitis, not elsewhere classified	0.632	0.368
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.632	0.368
T21 Burn and corrosion of trunk	0.631	0.368
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.631	0.369
C19 Malignant neoplasm of rectosigmoid junction	0.631	0.369
I08.9 Multiple valve disease, unspecified	0.630	0.370
S02.3 Fracture of orbital floor	0.630	0.370
S98 Traumatic amputation of ankle and foot	0.630	0.370
S97 Crushing injury of ankle and foot	0.630	0.370
S96 Injury of muscle and tendon at ankle and foot level	0.630	0.370
S95 Injury of blood vessels at ankle and foot level	0.630	0.370
S94 Injury of nerves at ankle and foot level	0.630	0.370
C18.6 Descending colon	0.630	0.370
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.629	0.371
I65.8 Occlusion and stenosis of other precerebral artery	0.629	0.371
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.629	0.371
I65.1 Occlusion and stenosis of basilar artery	0.629	0.371
I65.0 Occlusion and stenosis of vertebral artery	0.629	0.371
M13.9 Arthritis, unspecified	0.628	0.372
I27.8 Other specified pulmonary heart diseases	0.628	0.372
I27.1 Kyphoscoliotic heart disease	0.628	0.372
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.628	0.372
B90-B94 Sequelae of infectious and parasitic diseases	0.627	0.373
S99 Other and unspecified injuries of ankle and foot	0.625	0.375
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.625	0.375
D69.8 Other specified haemorrhagic conditions	0.625	0.375
D69.2 Other nonthrombocytopenic purpura	0.625	0.375
D69.1 Qualitative platelet defects	0.625	0.375
D69.0 Allergic purpura	0.625	0.375
S93.0 Dislocation of ankle joint	0.624	0.376
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.624	0.376
S81 Open wound of lower leg	0.624	0.376
B65-B83 Helminthiases	0.624	0.376
T15-T19 Effects of foreign body entering through natural orifice	0.624	0.376
S02.7 Multiple fractures involving skull and facial bones	0.623	0.377
Q60-Q64 Congenital malformations of the urinary system	0.623	0.377
C22.1 Intrahepatic bile duct carcinoma	0.622	0.377
C18.8 Overlapping lesion of colon	0.622	0.378
G03 Meningitis due to other and unspecified causes	0.621	0.378
S06.6 Traumatic subarachnoid haemorrhage	0.621	0.379
I08.2 Disorders of both aortic and tricuspid valves	0.621	0.379
B50-B64 Protozoal diseases	0.621	0.379
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.621	0.379
Q78 Other osteochondrodysplasias	0.621	0.379
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.621	0.379
Q75 Other congenital malformations of skull and face bones	0.621	0.379
Q74 Other congenital malformations of limb(s)	0.621	0.379
Q73 Reduction defects of unspecified limb	0.621	0.379
Q72 Reduction defects of lower limb	0.621	0.379
Q71 Reduction defects of upper limb	0.621	0.379
Q70 Syndactyly	0.621	0.379
Q69 Polydactyly	0.621	0.379
Q68 Other congenital musculoskeletal deformities	0.621	0.379
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.621	0.379
N02.7 Diffuse crescentic glomerulonephritis	0.620	0.379
N02.6 Dense deposit disease	0.620	0.379
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.620	0.379
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.620	0.379
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.620	0.379
N02.2 Diffuse membranous glomerulonephritis	0.620	0.379
N02.1 Focal and segmental glomerular lesions	0.620	0.379
N02.0 Minor glomerular abnormality	0.620	0.379
D40.1 Testis	0.620	0.380
C49.1 Connective and soft tissue of upper limb, including shoulder	0.620	0.380
S00.2 Other superficial injuries of eyelid and periocular area	0.620	0.380
C79.2 Secondary malignant neoplasm of skin	0.619	0.381
C78.1 Secondary malignant neoplasm of mediastinum	0.619	0.381
N18.4 Chronic kidney disease, stage 4	0.618	0.382

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations